HORIGUCHI Shigetoshi 堀口茂俊

Researcher Number	30293468
External Links
Affiliation (based on the past Project Information) *help	2011: Chiba University, 医学(系)研究科(研究院), 講師 2007 – 2011: Chiba University, 大学院・医学研究院, 講師 2006: Chiba University, Graduate School of Medicine, Professor, Assistant Professor, 大学院医学研究院, 講師 2005: 千葉大学, 大学院・医学研究院, 助手
Review Section/Research Field	Principal Investigator Otorhinolaryngology Except Principal Investigator Otorhinolaryngology
Keywords	Principal Investigator アレルギー / 免疫 / 記憶免疫 / Th2細胞 / 花粉症 / Th2 細胞 / 鼻アレルギー / メモリーT細胞 / 免疫記憶 / 免疫学 / アレルギー・ぜんそく / ぜんそく … More Except Principal Investigator … More Th2細胞 / NKT細胞 / アレルギー性鼻炎 / upper respiratory infection / Th2 cell / Th1 cell / cedar pollinosis / allergic rhintis / 鼻粘膜過敏性 / ウイルス / 気道感染 / 上気道感染 / Th1細胞 / スギ花粉症 / 抗原提示細胞 / 粘膜投与 / 免疫療法 / 頭頸部癌 / Th2サイトカイン / Th2 細胞 / Th2 サイトカイン / NKT 細胞 / 好酸球性副鼻腔炎 Less

口腔底(舌下)粘膜から投与するワクチンの免疫応答の特殊性Principal Investigator
- Principal Investigator
  
  堀口茂俊
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Adjuvant cellular immnunotherapy for head and neck cancer
- Principal Investigator
  
  OKAMOTO Yoshitaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Role of NKT cells in the eosinophilic diseases in upper respiratory tract and approachfor a new treatment
- Principal Investigator
  
  OKAMOTO Yoshitaka
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Seasonal changes in antigen-specific T-helper clone sizes and their memory functions in patients with Japanese cedar pollinosisPrincipal Investigator
- Principal Investigator
  
  HORIGUCHI Shigetoshi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University
Role of infectious diseases in allergic rhinitis
- Principal Investigator
  
  OKAMOTO Yoshitaka
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Chiba University

All 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation Book

[Book] アレルギー疾患の治療2010
- Author(s)
  堀口茂俊
- Total Pages
  415
- Publisher
  中外医薬社
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] Migration and immunological reaction after the administration of α-GalCer-pulsed- antigen-presenting cells into the submucosa of patients with head and neck cancer2011
- Author(s)
  Kurosaki, M., Horiguchi, S., Yamasaki, K., Uchida, Y., Motohashi, S., Nakayama, T., Sugimoto, A., Okamoto, Y
- Journal Title
  
  Cancer Immunology and Immunotherapy
  
  Volume: 60 Pages: 207-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390458
[Journal Article] Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy2011
- Author(s)
  Yamasaki, K., Horiguchi, S., Kurosaki, M., Kunii, N., Nagato, K., Hanaoka, H., Shimizu, N., Ueno, N., Yamamoto, S., Taniguchi, M., Motohashi, S., Nakayama, T., Okamoto, Y
- Journal Title
  
  Clinical Immunology
  
  Volume: 138 Pages: 255-265
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390458
[Journal Article] Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy2011
- Author(s)
  Okamoto Y, Fujikawa A, Kurosaki M, Yamasaki K, Sakurai D, Horiguchi S, Nakayama T
- Journal Title
  
  Advances in Oto-Rhino-Laryngology
  
  Volume: 72 Pages: 149-152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390458
[Journal Article] Migration and immunological reaction after the administration of a Ga1Cer-pulsed antigen-presenting cells into the submucosa of patients with head and neck cancer.2011
- Author(s)
  Kurosaki M, Horiguchi S, Yamasaki K, Uchida Y, Motohashi S, Nakayama T, Sugimoto A, Okamoto Y.
- Journal Title
  
  Cancer Immunol Itnmunother.
  
  Volume: 60(2) Pages: 207-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591895
[Journal Article] スギ特異的免疫療法はヒノキ花粉にも有効ですか2010
- Author(s)
  堀口茂俊
- Journal Title
  
  アレルギーの臨床 29巻
  
  Pages: 184-186
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] 成人に対する舌下免疫療法2010
- Author(s)
  堀口茂俊
- Journal Title
  
  アレルギーの臨床 30-3
  
  Pages: 225-230
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer2010
- Author(s)
  Kobayashi, K., Tanaka, Y., Horiguchi, S., Yamamoto, S., Nakayama, T., Sugimoto, A., Okamoto, Y
- Journal Title
  
  Cancer Immunology and Immunotherapy
  
  Volume: 59 Pages: 1503-1509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390458
[Journal Article] 成人に対する舌下免疫療法2010
- Author(s)
  堀口茂俊
- Journal Title
  
  アレルギーの臨床 30巻
  
  Pages: 225-230
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] Combination Therapy of In vitro Expanded Natural Killer T Cells and α-Galactosylceramide-pulsed Antigen Presenting Cells in Patients with Recurrent Head and Neck Carcinoma2009
- Author(s)
  Kumii, N., Horiguchi, S., Motohashi, S., Yamamoto, H., Ueno, N., Yamamoto, S., Sakurai, D., Taniguchi, M., Nakayama, T., Okamoto, Y
- Journal Title
  
  Cancer Science
  
  Volume: 100 Pages: 1092-1098
- NAID
  10025146740
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390458
[Journal Article] アレルギー性鼻炎のメジャーアレルゲンについて2009
- Author(s)
  堀口茂俊
- Journal Title
  
  JOHNS 25巻
  
  Pages: 301-303
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] 花粉症の免疫治療の現状2009
- Author(s)
  堀口茂俊
- Journal Title
  
  Medical Science Digest 35
  
  Pages: 19-21
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] アレルギー性鼻炎のメジャー・アレルゲンについて教えてください(Q&A)2009
- Author(s)
  堀口茂俊
- Journal Title
  
  JOHNS 25-3
  
  Pages: 301-303
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] 花粉症の免疫治療の現状2009
- Author(s)
  堀口茂俊
- Journal Title
  
  Medical Science Digest 35巻
  
  Pages: 19-21
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] スギ特異的免疫療法はヒノキ花粉症にも有効ですか?(Q&A)2009
- Author(s)
  堀口茂俊
- Journal Title
  
  アレルギーの臨床 29-2
  
  Pages: 184-186
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] A randomized controled trial of subhngual immunotherapy for Japanese cedar pollinosis.2008
- Author(s)
  Horiguchi s
- Journal Title
  
  Int Arch Allergy Immunol. 146
  
  Pages: 76-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] Seasonal changes in antigen-specific T-helper clone sizes in patients with Japanese cedar pollinosis: a 2-years study.2008
- Author(s)
  Horiguchi S
- Journal Title
  
  Clin Exp Allergy 38
  
  Pages: 405-412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] Lowered effectiveness of immunotherapy for cypress pollinosis by using Japanese cedar pollen extract2008
- Author(s)
  Horiguchi S, Okamoto Y, Yonekura S, Okawa T, Kunii N, Yamamoto H, Sakurai D, Hanazawa T.
- Journal Title
  
  Arerugi 57(5)
  
  Pages: 558-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] Seasonal changes in antigen-specific T-helper clone sizes in patients with Japanese cedar pollinosis : a 2-year study2008
- Author(s)
  Horiguchi S, Tanaka Y, Uchida T, Chazono H, Okawa T, Sakurai D, Okamoto Y.
- Journal Title
  
  Clin Exp Allergy 38(3)
  
  Pages: 405-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] A randomized controlled trial of sublingual immunotherapy for Japanese cedar pollinosis2008
- Author(s)
  Horiguchi S, Okamoto Y, Yonekura S, Okawa T, Yamamoto H, Kunii N, Sakurai D, Fujimura T, Nakazawa K, Yasueda H.
- Journal Title
  
  Int Arch Allergy Immunol. 146(1)
  
  Pages: 76-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19591957
[Journal Article] Detection of natural killer T cells in the sinus mucosa from asthmatics with chronic sinusitis2007
- Author(s)
  Yamamoto H, Okamoto Y, Horiguchi S, Kunii N, Yonekura S, Nakayama T.
- Journal Title
  
  Allergy 62
  
  Pages: 1451-1455
- Data Source
  KAKENHI-PROJECT-19591956
[Journal Article] 急性感染症が上気道・下気道の慢性炎症に及ぼす影響について2006
- Author(s)
  堀口茂俊
- Journal Title
  
  アレルギー科 21・2
  
  Pages: 135-139
- Data Source
  KAKENHI-PROJECT-17591776
[Journal Article] Influence of viral infection on the development of nasal hypersensitivity2005
- Author(s)
  Y.Okamoto, Z.Matsuzaki, T.Matsuoka, S.Endo, H.Yamamoto, H.Chazono, S.Horiguchi, T.Hanazawa
- Journal Title
  
  Clinical and Experimental Allergy 35
  
  Pages: 679-684
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17591776
[Journal Article] Present situation of cedar pollinosis in Japan and its immune responses
- Author(s)
  Okamoto Y, Horiguchi S, YamamotoH, YonekuraS, Hanazawa T.
- Journal Title
  
  Allergology International (in press)
- NAID
  10025109444
- Data Source
  KAKENHI-PROJECT-19591956
[Presentation] 口腔底(舌下)粘膜から投与するワクチンの免疫応答の特殊性2011
- Author(s)
  堀口茂俊
- Organizer
  耳鼻咽喉科免疫アレルギー学会
- Place of Presentation
  大分
- Year and Date
  2011-02-12
- Data Source
  KAKENHI-PROJECT-22591895
[Presentation] 新しい頭頸部癌治療の展望:自然免疫系(NKT細胞)を利用した細胞免疫療法2011
- Author(s)
  山崎一樹, 茶薗英明, 堀口茂俊, 花澤豊行, 岡本美孝
- Organizer
  第35回日本頭頸部癌学会
- Place of Presentation
  名古屋
- Year and Date
  2011-06-09
- Data Source
  KAKENHI-PROJECT-21390458
[Presentation] 頭頸部扁平上皮癌に対する活性化NKT細胞とα-GalCerパルス抗原提示細胞投与による第二相臨床試験2010
- Author(s)
  山崎一樹, 堀口茂俊, 藤川陽, 佐々原剛, 米倉修二, 花澤豊行, 岡本美孝
- Organizer
  第111回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  仙台
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-21390458
[Presentation] アレルギーの感作成立=発症なのか?アレルギー性鼻炎に関して2009
- Author(s)
  堀口茂俊
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-19591957
[Presentation] 免疫療法の位置づけと展望 : スギ花粉症に対して (シンポジウム)2009
- Author(s)
  堀口茂俊
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-27
- Data Source
  KAKENHI-PROJECT-19591957
[Presentation] アレルギーの感作成立=発症なのか? アレルギー性鼻炎に関して (シンポジウム)2009
- Author(s)
  堀口茂俊
- Organizer
  第59回日本アレルギー学会秋季学術大会
- Place of Presentation
  秋田市
- Year and Date
  2009-10-29
- Data Source
  KAKENHI-PROJECT-19591957
[Presentation] アレルギー性鼻炎及び頭頸部癌における抗原特異的T細胞の検討と臨床への応用2008
- Author(s)
  堀口茂俊
- Organizer
  第47回日本鼻科学会学会賞記念講演
- Place of Presentation
  名古屋市
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19591957
[Presentation] アレルギー性鼻炎及び頭頸部癌における抗原特異的T細胞の検討と臨床への応用2008
- Author(s)
  堀口茂俊
- Organizer
  第47回日本鼻科学会学会賞記念講演
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-09-25
- Data Source
  KAKENHI-PROJECT-19591957
[Presentation] 慢性副鼻腔炎の病態形成に及ぼす喘息合併の意義2007
- Author(s)
  山本陛三朗. 堀口茂俊. 岡本美孝
- Organizer
  第57 回日本アレルギー学会秋季学術大会
- Place of Presentation
  横浜市
- Year and Date
  2007-11-01
- Data Source
  KAKENHI-PROJECT-19591956

1. OKAMOTO Yoshitaka (40169157)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. HANAZAWA Toyoyuki (90272327)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. YAMASAKI Kazuki (00422238)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. OKAWA Toru (40344981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

HORIGUCHI Shigetoshi 堀口 茂俊

Research Projects

Research Products

Co-Researchers

口腔底(舌下)粘膜から投与するワクチンの免疫応答の特殊性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Adjuvant cellular immnunotherapy for head and neck cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of NKT cells in the eosinophilic diseases in upper respiratory tract and approachfor a new treatment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Seasonal changes in antigen-specific T-helper clone sizes and their memory functions in patients with Japanese cedar pollinosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of infectious diseases in allergic rhinitis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] アレルギー疾患の治療2010

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Migration and immunological reaction after the administration of α-GalCer-pulsed- antigen-presenting cells into the submucosa of patients with head and neck cancer2011

Author(s)

Journal Title

Data Source

[Journal Article] Induction of NKT cell-specific immune responses in cancer tissues after NKT cell-targeted adoptive immunotherapy2011

Author(s)

Journal Title

Data Source

[Journal Article] Nasal submucosal administration of antigen-presenting cells induces effective immunological responses in cancer immunotherapy2011

Author(s)

Journal Title

Data Source

[Journal Article] Migration and immunological reaction after the administration of a Ga1Cer-pulsed antigen-presenting cells into the submucosa of patients with head and neck cancer.2011

Author(s)

Journal Title

Data Source

[Journal Article] スギ特異的免疫療法はヒノキ花粉にも有効ですか2010

Author(s)

Journal Title

Data Source

[Journal Article] 成人に対する舌下免疫療法2010

Author(s)

Journal Title

Data Source

[Journal Article] The effect of radiotherapy on NKT cells in patients with advanced head and neck cancer2010

Author(s)

Journal Title

Data Source

[Journal Article] 成人に対する舌下免疫療法2010

Author(s)

Journal Title

Data Source

[Journal Article] Combination Therapy of In vitro Expanded Natural Killer T Cells and α-Galactosylceramide-pulsed Antigen Presenting Cells in Patients with Recurrent Head and Neck Carcinoma2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] アレルギー性鼻炎のメジャーアレルゲンについて2009

Author(s)

Journal Title

Data Source

HORIGUCHI Shigetoshi 堀口茂俊