yano seiji 矢野聖二

… Alternative Names

YANO Seiji 矢野聖二

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Researcher Number	30294672
Other IDs
External Links
Affiliation (Current)	2022: 金沢大学, 医学系, 教授 2022: 金沢大学, がん進展制御研究所, 教授
Affiliation (based on the past Project Information) *help	2011 – 2021: 金沢大学, がん進展制御研究所, 教授 2015: 金沢大学, がん進展制御研究所・腫瘍内科, 教授 2007 – 2010: Kanazawa University, がん研究所, 教授 2006: The University of Tokushima, Institute of Health Biosciences, Associate Professor, 大学院ヘルスバイオサイエンス研究部, 助教授 2006: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 講師 … More 2003 – 2005: 徳島大学, 医学部・歯学部附属病院, 講師 2002: The University of Tokushima, University Hospital, Assistant Professor, 医学部附属病院, 講師 2000 – 2001: 徳島大学, 医学部・附属病院, 講師 Less
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Respiratory organ internal medicine / Biological Sciences / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Biological Sciences / Digestive surgery / Respiratory organ internal medicine / Respiratory organ internal medicine / Respiratory surgery
Keywords	Principal Investigator VEGF / 血管新生 / EGFR-TKI / 分子標的薬耐性 / 肺がん / 肺癌 / 脳転移 / 胸膜中皮腫 / 同所移植モデル / 胸水 … More / 薬剤耐性 / HGF / Met / 線維芽細胞 / 分子標的薬 / ALK阻害薬耐性 / MYO18B / MMP / MMP阻害剤 / 浸潤 / 癌性胸水 / VEGF受容体阻害剤 / 血管透過性 / RET / チロシンキナーゼ阻害薬 / 分子標的治療 / 抗体治療 / 抗癌剤 / EGFR遺伝子変異 / バイオマーカー / PI3K / 公子標的治療 / 肝細胞増殖因子 / MET / 上皮成長因子受容体 / ゲフィチニブ / 微小環境 / EGFR変異肺がん / ALK肺がん / 中皮腫 / ALK阻害薬 / EGFRリガンド / EMT / ヒストン脱メチル化酵素 / 腫瘍 / ALK-TKI / FGFR1 / PDGFR / 腫瘍血管 / EGFR / 骨転移 / がん性胸膜炎 / 転移 / イメージング / がん性胸水 / がん性髄膜炎 / BIM遺伝子多型 / EGFR阻害薬耐性 / mTOR阻害薬 / 個別化医療 / ボリノスタット / 悪性胸膜中皮腫 / 抗癌剤耐性 / EGF受容体 / malignant pleural mesothelioma / orthotopic implantation model / pleural effusion / resistance to anticancer drugs / EGF receptor / 髄膜がん腫症 / 髄膜がん種症 / 耐性変異 / 中枢神経系転移 / NTRK1融合遺伝子陽性がん / 抵抗性 / EGFR変異 / ALK融合遺伝子 / NTRK1融合遺伝子 / 耐性 / EML4-ALK / 抵抗性細胞 / AXL / インスリン様増殖因子受容体 / IGF-1R / 転写因子 / FOXA1 … More Except Principal Investigator 肺癌 / 血管新生 / VEGF / 分子標的治療 / 胃癌 / 癌性腹膜炎 / PTHrP / 癌性胸水 / 骨転移 / 多臓器転移 / 樹状細胞 / 免疫療法 / 薬剤耐性 / HGF / EGFR / HGF/MET axis / スキルス胃癌 / MRK16 / VEGF受容体 / 血管標的薬 / EGF受容体 / MMP / 臓器微小環境 / cDNAマイクロアレイ / 浸潤 / 免疫遺伝子治療 / KAI1 / CD82 / ガングリオシド / 抗体療法 / 破骨細胞 / 可溶性VEGF受容体 / EGFR阻害薬 / 肝細胞増殖因子 / 抗HM1.24抗原 / マルチキナーゼ阻害薬 / 胸膜中皮腫 / organotropism / 抗PTHrP抗体 / ビスフォスフォネート / HM1.24抗原 / ADCC / 耐性 / ゲフィチニブ / マイクロアレイ / プロテオーム解析 / 脳転移 / 蛍光気管支鏡 / MYO18B / Src / CD9 / 胃十二指腸外科学 / 腹膜播種(癌性腹膜炎) / CXCR4/CXCL12 axis / Amphiregulin / HB-EGF / EGFR ligands / 癌微小環境 / HER4 / CXCR4 / CXCL12 axis / EGF / 微小環境 / シグナル伝達 / 生体材料 / 生体イメージング / ゲノム科学 / がん微小環境 / がん浸潤 / 転移 / リンパ管新生 / ゲノム医学 / がん性腹膜炎 / MET/HGF / パラクリン活性経路 / MET TKI / パラクリン経路 / MET / DDX3X / Wnt/β-catenin / EGFR遺伝子変異陽性肺癌 / PD-1 / beta-catenin / VEGFR / β-catenin / 癌幹細胞 / 癌間質線維芽細胞 / 癌間質細胞 / HGF高産生性 / SMA陽性活性化線維芽細胞 / スキル胃癌 / 癌間質増生 / HGF/MET / α-SMA / Galectin-1 / CAF / galectin-1 / 多剤耐性 / P糖蛋白質 / single chain antibody fragment / P糖蛋白 / single chan抗体 / ケモカイン / 抗体治療 / MRK-16 / MCP-1 / Multi-drug resistance / P-glycoprotein / single chain antibody / EMT / EGFR肺癌 / AXL / EGFR変異肺癌 / 第3世代-TKI / 悪性胸膜中皮腫 / 温熱療法 / 化学療法 / 呼吸器外科学 Less

Formation of a non-clinical research base for treatment aimed to eradicate lung cancer by targeted drugsPrincipal Investigator
- Principal Investigator
  
  Yano Seiji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kanazawa University
Study to circumvent targeted drug resistance in leptomeningeal carcinomatosis of lung cancerPrincipal Investigator
- Principal Investigator
  
  Yano Seiji
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Combined treatment of hyperthermia therapy using novel ferromagnet and mTOR inhibitor for malignant pleural mesothelioma
- Principal Investigator
  
  TAMURA MASAYA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory surgery
- Research Institution
  Kanazawa University
Molecular targeted medicine to inhibit cancer stemness
- Principal Investigator
  
  Kagamu Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Saitama Medical University
  Niigata University
Elucidation of essential molecular mechanism by which cancer stroma cause the development of peritoneal carcinomatosis into scirrhous gastric cancer.
- Principal Investigator
  
  YASUMOTO Kazuo
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa Medical University
  Kanazawa University
Development of therapies for overcoming EMT-associated irreversible tyrosine kinase inhibitor resistance in EGFR lung cancer
- Principal Investigator
  
  Fukuda Koji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Study to overcome metastasis and targeted drug-resistance of lung cancerPrincipal Investigator
- Principal Investigator
  
  YANO Seiji
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Novel target therapy for the HGF/cMET axis and HB-EGF in gastric cancer
- Principal Investigator
  
  YASUMOTO Kazuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Integrative Research on Cancer Microenvironment Network
- Principal Investigator
  
  MIYAZONO Kohei
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Development of novel therapy targeting microenvironment in respiratory malignancyPrincipal Investigator
- Principal Investigator
  
  YANO Seiji
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kanazawa University
Development of individual therapy for overcoming HGF-induced molecular targeted drug-resistance in EGFR-mutant lung cancerPrincipal Investigator
- Principal Investigator
  
  YANO Seiji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Development of molecular target therapy for gastric cancer targeted for the CXCR4/CXCL12 axis and HB-EGF
- Principal Investigator
  
  YASUMOTO Kazuo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Digestive surgery
- Research Institution
  Kanazawa University
Identification of real target of VEGF receptor inhibitor which shows dramatic cytotoxic effect against pleural mesotheliomaPrincipal Investigator
- Principal Investigator
  
  YANO Seiji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kanazawa University
Development of molecular targeted therapy for lung cancer metastasis considering characteristics of organ microenvironment
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
Development of molecular targeted therapy for malignant pleural mesotheliomaPrincipal Investigator
- Principal Investigator
  
  YANO Seiji
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima
Studies on the generation and application of fusion protein of single chain antibody for P-glycoprotein and chemokine
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima
肺がんの転移・血管新生分子を標的とした生物学的制御法開発
- Principal Investigator
  
  SONE Saburo
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokushima
肺癌脳転移と癌性胸膜炎における血管新生の分子生物学的検討と新規治療法開発Principal Investigator
- Principal Investigator
  
  矢野聖二
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  The University of Tokushima

[Book] Cancer growth and progression : integration/interaction of oncologic growth2005
- Author(s)
  Yano S
- Total Pages
  454
- Publisher
  Organtropism of lung cancer metastasis and its molecular targeted therapy.
- Data Source
  KAKENHI-PROJECT-17590792
[Journal Article] STAT3 inhibition suppresses adaptive survival of ALK-rearranged lung cancer cells through transcriptional modulation of apoptosis2022
- Author(s)
  Yanagimura N, Takeuchi S, Fukuda K, Arai S, Tanimoto A, Nishiyama A, Ogo N, Takahashi H, Asai A, Watanabe S, Kikuchi T, Yano S.
- Journal Title
  
  npj Precision Oncology
  
  Volume: 6 Pages: 11-11
- DOI
  10.1038/s41698-022-00254-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18KT0019, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-20H03688, KAKENHI-PROJECT-21H02609, KAKENHI-PROJECT-20K08516
[Journal Article] Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer.2021
- Author(s)
  Fukuda Koji、Otani Sakiko、Takeuchi Shinji、Arai Sachiko、Nanjo Shigeki、Tanimoto Azusa、Nishiyama Akihiro、Naoki Katsuhiko、Yano Seiji
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Pages: 3784-3795
- DOI
  10.1111/cas.15035
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17213, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-21K07172
[Journal Article] Proteasome inhibition overcomes ALK-TKI resistance by p53 inactivation through Noxa expression in ALK-rearranged NSCLC.2021
- Author(s)
  Tanimoto Azusa、Matsumoto Shingo、Takeuchi Shinji、Arai Sachiko、Fukuda Koji、Nishiyama Akihiro、Yoh Kiyotaka、Ikeda Takaya、Furuya Naoki、Nishino Kazumi、Ohe Yuichiro、Goto Koichi、Yano Seiji
- Journal Title
  
  Clin Cancer Res
  
  Volume: 27 Pages: 1410-1420
- DOI
  10.1158/1078-0432.ccr-20-2853
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08516, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-18K15922
[Journal Article] MET amplification results in heterogenous responses to osimertinib in EGFR-mutant lung cancer previously treated with erlotinib.2020
- Author(s)
  Nishiyama Akihiro、Takeuchi Shinji、Adachi Yuta、Otani Sakiko、Tanimoto Azusa、Sasaki Motoko、Matsumoto Shingo、Goto Koichi、Yano Seiji
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Pages: 3813-23
- DOI
  10.1111/cas.14593
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08516, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-18K06985
[Journal Article] Glycogen synthase kinase-3 inhibition overcomes epithelial-mesenchymal transition-associated resistance to osimertinib in EGFR-mutant lung cancer.2020
- Author(s)
  Fukuda Koji、Takeuchi Shinji、Arai Sachiko、Kita Kenji、Tanimoto Azusa、Nishiyama Akihiro、Yano Seiji
- Journal Title
  
  Cancer Sci
  
  Volume: 111 Pages: 2374-2384
- DOI
  10.1111/cas.14454
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08516, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-18K07261
[Journal Article] Resminostat, a histone deacetylase inhibitor, circumvents tolerance to EGFR inhibitors in EGFR-mutated lung cancer cells with <i>BIM</i> deletion polymorphism2020
- Author(s)
  Arai S, Yano S, et al.
- Journal Title
  
  The Journal of Medical Investigation
  
  Volume: 67(3.4) Issue: 3.4 Pages: 343-350
- DOI
  10.2152/jmi.67.343
- NAID
  130007936892
- ISSN
  1343-1420, 1349-6867
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-17K09649
[Journal Article] Transient IGF-1R inhibition combined with osimertinib eradicates AXL-low expressing EGFR mutated lung cancer2020
- Author(s)
  Rong Wang, Tadaaki Yamada, Kenji Kita, Hirokazu Taniguchi, Sachiko Arai, Koji Fukuda, Minoru Terashima, Hisanori Uehara, Xujun Han, Kunio Matsumoto, Wei Wang, Takeshi Suzuki, Seiji Yano, et al.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Pages: 1-1
- DOI
  10.1038/s41467-020-18442-4
- NAID
  120007186801
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07346, KAKENHI-PROJECT-19K07686, KAKENHI-PROJECT-19K22578, KAKENHI-PROJECT-20K22837, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-19H03499, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-18K06057, KAKENHI-PROJECT-18K08141, KAKENHI-PROJECT-16H06279
[Journal Article] Phase I study of vorinostat with gefitinib in BIM deletion polymorphism/EGFR mutation double-positive lung cancer. Cancer Sci, 2019 Nov 29. doi: 10.1111/cas.14260.2020
- Author(s)
  Shinji Takeuchi, Tetsunari Hase, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 561-57
- DOI
  10.1111/cas.14260
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09649, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-18K07443
[Journal Article] Caput Medusae-like Venous Dilatation in Lung Cancer2019
- Author(s)
  Adachi Y, Yano S.
- Journal Title
  
  Internal Medicine
  
  Volume: 58(22) Issue: 22 Pages: 3341-2
- DOI
  10.2169/internalmedicine.2577-18
- NAID
  130007746035
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03665
[Journal Article] Epithelial-to-Mesenchymal Transition Is a Mechanism of ALK Inhibitor Resistance in Lung Cancer Independent of ALK Mutation Status2019
- Author(s)
  Fukuda K, Takeuchi S,Yano S, et al.
- Journal Title
  
  Cancer Research
  
  Volume: 79(7) Pages: 1658-1670
- DOI
  10.1158/0008-5472.can-18-2052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-16H04715, KAKENHI-PROJECT-17K09649, KAKENHI-PROJECT-19K07346, KAKENHI-PROJECT-19H03665
[Journal Article] Distribution and activity of lenvatinib in brain tumor models of human anaplastic thyroid cancer cells in severe combined immune deficient mice.2019
- Author(s)
  Wang Rong、Yamada Tadaaki、Arai Sachiko、Fukuda Koji、Taniguchi Hirokazu、Tanimoto Azusa、Nishiyama Akihiro、Takeuchi Shinji、Yamashita Kaname、Ohtsubo Koshiro、Matsui Junji、Onoda Naoyoshi、Hirata Eishu、Taira Shu、Yano Seiji
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: x Pages: 947-56
- DOI
  10.1158/1535-7163.mct-18-0695
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07181, KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-16K04890, KAKENHI-PROJECT-19H03665
[Journal Article] Patient - derived xenograft models of non - small cell lung cancer for evaluating targeted drugsensitivity and resistance2019
- Author(s)
  Kita K., Fukuda K., Takahashi H., Tanimoto A., Nishiyama A., Arai S., Takeuchi S., Yamashita K., Ohtsubo K., Otani S., Yanagimura N., Suzuki C., Ikeda H., Tamura M., Matsumoto I., Yano S.
- Journal Title
  
  Cancer Science
  
  Volume: 110(10) Pages: 3215-24
- DOI
  10.1111/cas.14171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08141, KAKENHI-PROJECT-19K06454, KAKENHI-PROJECT-19H03665, KAKENHI-PUBLICLY-17H05659, KAKENHI-PROJECT-19K22892, KAKENHI-PROJECT-18H03330
[Journal Article] AXL confers intrinsic resistance to osimertinib and advances the emergence of tolerant cells.2019
- Author(s)
  Taniguchi H, Yamada T, Wang R, Tanimura K, Adachi Y, Nishiyama A, Tanimoto A, Takeuchi S, Araujo LH, Boroni M, Yoshimura A, Shiotsu S, Matsumoto I, Watanabe S, Kikuchi T, Miura S, Tanaka H, Kitazaki T, Yamaguchi H, Mukae H, Uchino J, Uehara H, Takayama K, Yano S.
- Journal Title
  
  Nature Communications
  
  Volume: 10 Pages: 259-259
- DOI
  10.1038/s41467-018-08074-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09649, KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-18KT0019, KAKENHI-PROJECT-19K08608, KAKENHI-PROJECT-19H03665
[Journal Article] Distinct dependencies on receptor tyrosine kinases in the regulation of MAPK signaling between BRAF V600E and non-V600E mutant lung cancers.2018
- Author(s)
  Kotani Hiroshi、Adachi Yuta、Kitai Hidenori、Tomida Shuta、Bando Hideaki、Faber Anthony C.、Yoshino Takayuki、Voon Dominic C.、Yano Seiji、Ebi Hiromichi
- Journal Title
  
  Oncogene
  
  Volume: 37 Pages: 1775-1787
- DOI
  10.1038/s41388-017-0035-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10784, KAKENHI-PUBLICLY-16H01574, KAKENHI-PROJECT-15KK0303, KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-16K07164
[Journal Article] Foretinib Overcomes Entrectinib Resistance Associated with the NTRK1 G667C Mutation in NTRK1 Fusion-Positive Tumor Cells in a Brain Metastasis Model.2018
- Author(s)
  Akihiro Nishiyama
- Journal Title
  
  Clin Cancer Res
  
  Volume: 24 Pages: 23572369-23572369
- DOI
  10.1158/1078-0432.ccr-17-1623
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15308, KAKENHI-PROJECT-16H05308
[Journal Article] Pulmonary carcinosarcoma showing an obvious response to pazopanib: a case report.2018
- Author(s)
  Tanimoro A, Yano S, et al.
- Journal Title
  
  BMC Pulm Med
  
  Volume: 18(1) Pages: 193-193
- DOI
  10.1186/s12890-018-0757-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] Histone deacetylase inhibition enhances the antitumor activity of a MEK inhibitor in lung cancer cells harboring RAS mutations. Mol Cancer Ther 2018 17:17-25. doi: 10.1158/1535-7163.MCT-17-0146.2018
- Author(s)
  Yamada T, Amann JM, Tanimoto A, Taniguchi H, Shukuya T, Timmers C, Yano S, Shilo K, Carbone DP.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 17 Pages: 17-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] Foretinib overcomes entrectinib resistance associated with the NTRK1 G667C mutation in NTRK1 fusion-positive tumor cells in a brain metastasis model.2018
- Author(s)
  22.Nishiyama A, Yamada T, Kita K, Wang R, Arai S, Fukuda K, Tanimoto A, Takeuchi S, Tange S, Tajima A, Furuya N, Kinoshita T, Yano S.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] Amphiregulin triggered EGFR activation confers crizotinib-resistance in a mouse model with EML4-ALK cancer and its circumvention with EGFR inhibitors.2017
- Author(s)
  Taniguchi H, Takeuchi S, Fukuda K, Nakagawa T, Arai S, Yamada T, Yamaguchi H, Mukae H, Yano S.
- Journal Title
  
  Cancer Sci
  
  Volume: 108 Pages: 53-60
- DOI
  10.1111/cas.13111
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] Resistance mediated by alternative receptor tyrosine kinases in FGFR1-amplified lung cancer.2017
- Author(s)
  Adachi Yuta、Watanabe Kazuyoshi、Kita Kenji、Kitai Hidenori、Kotani Hiroshi、Sato Yuki、Inase Naohiko、Yano Seiji、Ebi Hiromichi
- Journal Title
  
  Carcinogenesis
  
  Volume: 38 Pages: 1063-1072
- DOI
  10.1093/carcin/bgx091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07164, KAKENHI-PROJECT-16H05308
[Journal Article] The impact of MET inhibition on small-cell lung cancer cells showing aberrant activation of the HGF/MET pathway.2017
- Author(s)
  Taniguchi H, Yamada T, Takeuchi S, Arai S, Fukuda K, Sakamoto S, Kawada M, Yamaguchi H, Mukae H, Yano S.
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 1378-1385
- DOI
  10.1111/cas.13268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09649, KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-15K06888
[Journal Article] n vitro and in vivo anti-tumor activity of alectinib in tumor cells with NCOA4-RET.2017
- Author(s)
  Arai S*, Kita K*, Tanimoto A, Takeuchi T, Fukuda K, Sato H, Yano S. *: equally contribution.
- Journal Title
  
  Oncotarget
  
  Volume: 8 Pages: 73766-73
- DOI
  10.18632/oncotarget.17900
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] Podoplanin promotes progression of malignant pleural mesothelioma by regulating motility and focus formation.2017
- Author(s)
  Takeuchi S, Fukuda K, Yamada T, Arai S, Takagi S, Ishii G, Ochiai A, Iwakiri S, Itoi K, Uehara H, Nishihara H, Fujita N, Yano S.
- Journal Title
  
  Cancer Science
  
  Volume: 108 Pages: 696-703
- DOI
  10.1111/cas.13190
- NAID
  120006306235
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09649, KAKENHI-PROJECT-16H05308
[Journal Article] MET copy number gain is associated with gefitinib resistance in leptomeningeal carcinomatosis of EGFR- mutant lung cancer.2017
- Author(s)
  Nanjo S, Arai S, Wang W, Takeuchi S, Yamada T, Hata A, Katakami N, Okada Y, Yano S.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 16 Pages: 506-515
- DOI
  10.1158/1535-7163.mct-16-0522
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] MET copy number gain is associated with gefitinib resistance in leptomeningeal carcinomatosis of EGFR-mutant lung cancer.2017
- Author(s)
  Nanjo S, Arai S, Wang W, Takeuchi S, Yamada T, Hata A, Katakami N, Okada Y, Yano S.
- Journal Title
  
  Molecular Cancer Therapeutics
  
  Volume: 16 Pages: 506-15
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] Histone deacetylase 3 inhibition overcomes BIM deletion polymorphism-mediated osimertinib-resistance in EGFR-mutant lung cancer.2017
- Author(s)
  Tanimoto A, Takeuchi S, Arai S, Fukuda K, Yamada T, Roca X, Ong ST, Yano S.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 23 Pages: 3139-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05308
[Journal Article] In vivo imaging xenograft models for the evaluation of anti-brain-tumor efficacy of targeted drugs.2017
- Author(s)
  Kita K, Arai S, Nishiyama A, Taniguchi H, Fukuda K, Wang R, Yamada T, Takeuchi S, Tange S, Tajima A, Nakada M, Yasumoto K, Motoo Y, Murakami T, Yano S.
- Journal Title
  
  Cancer Med.
  
  Volume: 6 Pages: 2972-2983
- DOI
  10.1002/cam4.1255
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09649, KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-26461700, KAKENHI-PROJECT-15K13100
[Journal Article] High efficacy of third generation EGFR inhibitor AZD9291 in a leptomeningeal carcinomatosis model with EGFR-mutant lung cancer cells.2016
- Author(s)
  Nanjo S, Ebi H, Arai S, Takeuchi S, Yamada T, Mochizuki S, Okada Y, Nakada M, Murakami T, Yano S.
- Journal Title
  
  Oncotarget
  
  Volume: 7(4) Pages: 3847-3856
- DOI
  10.18632/oncotarget.6758
- NAID
  120005830568
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461700, KAKENHI-PROJECT-26830105, KAKENHI-PROJECT-16H05308, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-16K07164
[Journal Article] In vivo imaging models of bone and brain metastases and pleural carcinomatosis with a novel human EML4-ALK lung cancer cell line.2015
- Author(s)
  Nanjo S, Yano S, et al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 106 Pages: 244-252
- DOI
  10.1111/cas.12600
- NAID
  120005830611
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PLANNED-23112101, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24650625, KAKENHI-PROJECT-24659403, KAKENHI-PROJECT-25860640, KAKENHI-PROJECT-26250028, KAKENHI-PROJECT-26293322, KAKENHI-PROJECT-25462190, KAKENHI-PROJECT-25462202
[Journal Article] Lack of association between the BIM deletion polymorphism and the risk of lung cancer with and without EGFR mutations.2015
- Author(s)
  Ebi H, Yano S, et al.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 10 Pages: 59-66
- DOI
  10.1097/jto.0000000000000371
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25860640, KAKENHI-PROJECT-26830105
[Journal Article] LPP inhibits collective cell migration during lung cancer dissemination.2015
- Author(s)
  Tanaka M, Yano S, et al.
- Journal Title
  
  Oncogene
  
  Volume: in preｓs
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] LPP inhibits collective cell migration during lung cancer dissemination.2015
- Author(s)
  Tanaka M, Yano S, et al.
- Journal Title
  
  Oncogene
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Therapeutic activity of glycoengineered anti-GM2 antibodies against malignant pleural mesothelioma.2015
- Author(s)
  Li Q, Yano S, et al.
- Journal Title
  
  Cancer Sci
  
  Volume: 106 Pages: 102-107
- DOI
  10.1111/cas.12575
- NAID
  120005666336
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25290053
[Journal Article] The current state of molecularly targeted drugs targeting HGF/Met.2014
- Author(s)
  Yano S, Nakagawa T.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 44 Pages: 9-12
- DOI
  10.1093/jjco/hyt188
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209
[Journal Article] Distinct allelic expression patterns of imprinted IGF2 in adenocarcinoma and squamous cell carcinoma of the lung.2014
- Author(s)
  Ozaki S, Yano S, et al.
- Journal Title
  
  Oncol Lett
  
  Volume: 8 Pages: 2561-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Triple inhibition of EGFR, Met, and VEGF suppresses regrowth of HGF-triggered, erlotinib-resistant lung cancer harboring an EGFR mutation.2014
- Author(s)
  Nakade J, Yano S, et al.
- Journal Title
  
  Journal of Thoracic Oncology
  
  Volume: 9 Pages: 775-783
- DOI
  10.1097/jto.0000000000000170
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209
[Journal Article] Surfactant protein A suppresses lung cancer progression by regulating the polarization of tumor-associated macrophages.2014
- Author(s)
  Mitsuhashi A, Yano S, et al.
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 182 Pages: 1843-1853
- DOI
  10.1016/j.ajpath.2013.01.030
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24390210, KAKENHI-PROJECT-24591167, KAKENHI-PROJECT-24790814
[Journal Article] Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.2014
- Author(s)
  Tanimoto A, Yano S, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 4920-8
- NAID
  120005830567
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Not just gRASping at flaws: finding vulnerabilities to develop novel therapies for treating KRAS mutant cancers2014
- Author(s)
  Ebi H, Yano S, et al.
- Journal Title
  
  Ｃａｎｃｅｒ　Ｓｃｉｅｎｃｅ
  
  Volume: 105 Pages: 499505-499505
- DOI
  10.1111/cas.12383
- NAID
  120005830600
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-26830105
[Journal Article] Antitumor effect and antiangiogenic potential of the mTOR inhibitor temsirolimus against malignant pleural mesothelioma.2014
- Author(s)
  Moriya M, Yano S, et al.
- Journal Title
  
  Oncol Rep
  
  Volume: 31 Pages: 1109-15
- DOI
  10.3892/or.2013.2948
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209
[Journal Article] Clinical Significance of EGFR-TKI: Sensitivity and Resistance2014
- Author(s)
  Takeuchi S, Yano S.
- Journal Title
  
  Respir Investig
  
  Volume: 52 Pages: 348-356
- DOI
  10.1016/j.resinv.2014.10.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-25860640
[Journal Article] Receptor ligand-triggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4-ALK lung cancer cells.2014
- Author(s)
  Tanimoto A, Yano S, et al.
- Journal Title
  
  Oncotarget
  
  Volume: 5 Pages: 4920-8
- NAID
  120005830567
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Distinct allelic expression patterns of imprinted IGF2 in adenocarcinoma and squamous cell carcinoma of the lung.2014
- Author(s)
  Ozaki S, Yano S, et al.
- Journal Title
  
  Oncol Lett
  
  Volume: 8 Pages: 2561-4
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Clinical significance of epidermal growth factor receptor tyrosine kinase inhibitors: Sensitivity and resistance.2014
- Author(s)
  Takeuchi S, Yano S.
- Journal Title
  
  Respir Investig
  
  Volume: 52 Pages: 348-56
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Expression of Akt kinase-interacting protein 1, a scaffold protein of the PI3K/PDK1/Akt pathway, in pancreatic cancer.2014
- Author(s)
  Ohtsubo K, Yano S, et al.
- Journal Title
  
  Pancreas
  
  Volume: 43 Pages: 1093-100
- DOI
  10.1097/mpa.0000000000000168
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-24390209
[Journal Article] PI3K regulates MEK/ERK signaling in breast cancer via the Rac-GEF, P-Rex1.2013
- Author(s)
  Ebi H, Yano S, et al.
- Journal Title
  
  PNAS
  
  Volume: 110 Pages: 21124-9
- DOI
  10.1073/pnas.1314124110
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209
[Journal Article] EGFR-TKI resistance due to BIM polymorphism can be circumvented by in combination with HDAC inhibition.2013
- Author(s)
  Nakagawa T, Yano S, et al.
- Journal Title
  
  Cancer Res
  
  Volume: 73(8) Pages: 2428-34
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.2013
- Author(s)
  Nanjo S, Yano S, et al.
- Journal Title
  
  PLoS ONE
  
  Volume: 8
- DOI
  10.1371/journal.pone.0084700
- NAID
  120005368227
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209
[Journal Article] EGFR-TKI resistance due to BIM polymorphism can be circumvented in combination with HDAC inhibition2013
- Author(s)
  Nakagawa T, Yano S, et al..
- Journal Title
  
  Cancer Res.
  
  Volume: 73 Pages: 2428-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] Synchronous triple cancers of the pancreas, stomach, and cecum treated with S-1 followed by pancrelipase treatment of pancreatic exocrine insufficiency.2013
- Author(s)
  Ohtsubo K, Yano S, et al.
- Journal Title
  
  JOP
  
  Volume: 14 Pages: 515-20
- DOI
  10.6092/1590-8577/1719
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209
[Journal Article] Epigenetic circumvention of EGFR-TKI resistance due to BIM deletion polymorphism by HDAC inhibitor and EGFR-TKI2013
- Author(s)
  Nakagawa T, Yano S, et al.
- Journal Title
  
  Cancer Res
  
  Volume: 73 Pages: 2428-2434
- DOI
  10.1158/0008-5472.can-12-3479
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25860638, KAKENHI-PROJECT-25860640, KAKENHI-ORGANIZER-22112001
[Journal Article] mTOR inhibitors control the growth of EGFR mutant lung cancer even after acquiring resistance by HGF2013
- Author(s)
  Ishikawa D, Yasumoto K, Yano S, et al.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] KDM5B histone demethylase controls epithelial-mesenchymal transition of cancer cells by regulating the expression of the microRNA-200 family.2013
- Author(s)
  Enkhbaatar Z, Yano S, et al.
- Journal Title
  
  Cell Cycle
  
  Volume: 12 Pages: 2100-12
- DOI
  10.4161/cc.25142
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24590346, KAKENHI-PROJECT-25460266
[Journal Article] Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer2013
- Author(s)
  Zhao, L, Yasumoto, K, Yano, Seiji, et al.
- Journal Title
  
  Cancer Sci.
  
  Volume: 104 Pages: 1640-6
- NAID
  120005830610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] mTOR inhibitors control the growth of EGFR mutant lung cancer even after acquiring resistance by HGF2013
- Author(s)
  Ishikawa D, Yano S, et al.
- Journal Title
  
  Plos One
  
  Volume: 8
- DOI
  10.1371/journal.pone.0062104
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23591141, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24591156, KAKENHI-PROJECT-25860638, KAKENHI-PROJECT-25860640
[Journal Article] EGFR-TKI resistance due to BIM polymorphism can be circumvented by incombination with HDAC inhibition.2013
- Author(s)
  Nakagawa T, Yano S, et al.
- Journal Title
  
  Cancer Res
  
  Volume: 73(8) Pages: 2428-34
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Akt kinase-interacting protein1, a novel therapeutic target for lung cancer with EGFR-activating and gatekeeper mutations2013
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Oncogene
  
  Volume: 32 Pages: 4427-35
- DOI
  10.1038/onc.2012.446
- NAID
  120004997024
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-24300344, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24390210, KAKENHI-PROJECT-25860638, KAKENHI-PLANNED-22112008
[Journal Article] Novel PI3K-mTOR inhibitor, BEZ235, circumvents erlotinib -resistance of EGFR mutant lung cancer cells triggering by HGF2013
- Author(s)
  Sano T, Yano S, et al.
- Journal Title
  
  Int J Cancer
  
  Volume: 133 Pages: 505-13
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] The novel phosphoinositide 3-kinase-mammalian target of rapamycin inhibitor, BEZ235, circumvents erlotinib resistance of epidermal growth factor receptor mutant lung cancer cells triggered by hepatocyte growth factor2013
- Author(s)
  Sano T, Yano S, et al.
- Journal Title
  
  IntJ Cancer
  
  Volume: 133 Pages: 505-13
- DOI
  10.1002/ijc.28034
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25860638
[Journal Article] Paracrine activation of MET promotes peritoneal carcinomatosis in scirrhous gastric cancer2013
- Author(s)
  Zhao L, Yano S, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 104 Pages: 1640-1646
- DOI
  10.1111/cas.12301
- NAID
  120005830610
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23501273, KAKENHI-PROJECT-23591632, KAKENHI-PROJECT-23591921, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-25860640
[Journal Article] Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer.2012
- Author(s)
  Wang W, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(6) Pages: 1663-71
- NAID
  120003830985
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR mutant lung cancer.2012
- Author(s)
  Nakagawa T,Yano S, et al.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11(10) Pages: 2149-57
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Prognostic value of acquired resistance-related molecules in Japanese patients with NSCLC treated with an EGFR-TKI.2012
- Author(s)
  Uramoto H, Yano S, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 32(9) Pages: 3785-90
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR mutant lung cancer by decreasing client protein expression and angiogenesis2012
- Author(s)
  Koizumi H, Yamada T, Takeuchi S, Nakagawa T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, Yano S.
- Journal Title
  
  J Thorac Oncol
  
  Volume: (in press)
- NAID
  40019570662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR mutant lung cancer by decreasing client protein expression and angiogenesis2012
- Author(s)
  Koizumi H, Yamada T, Takeuchi S, Nakagawa T, Kita K, Nakamura T, Matsumoto K, Suda K, Mitsudomi T, and Yano S
- Journal Title
  
  J Thoracic Oncol
  
  Volume: Vol. 7: no.7 Pages: 1078-1085
- DOI
  10.1097/jto.0b013e3182519a2c
- NAID
  40019570662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24659403, KAKENHI-PLANNED-22112010
[Journal Article] Hepatocyte growth factor induces resistance to anti-epidermal growth factor receptor antibody in lung cancer.2012
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 7(2) Pages: 272-80
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Hepatocyte Growth Factor Induces Resistance to Anti-Epidermal Growth Factor Receptor Antibody in Lung Cancer2012
- Author(s)
  Yamada T, Takeuchi S, Kita K, Bando H, Nakamura T, Matsumoto K, Yano S
- Journal Title
  
  J Thoracic Oncol
  
  Volume: 7 Pages: 272-280
- DOI
  10.1097/jto.0b013e3182398e69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209
[Journal Article] Prognostic value of acquired resistance-related molecules in Japanese patients with NSCLC treated with an EGFR-TKI.2012
- Author(s)
  Uramoto H, Yano S, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 32(9) Pages: 3785-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] T790M is associated with a favorable prognosis in Japanese patients treated with an EGFR-TKI.2012
- Author(s)
  Uramoto T, Yano S, Tanaka F
- Journal Title
  
  Lung Cancer
  
  Volume: 76 Pages: 129-130
- DOI
  10.1016/j.lungcan.2012.01.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24390335
[Journal Article] Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer.2012
- Author(s)
  Takeuchi S, Yano S, et al.
- Journal Title
  
  Am J Pathol
  
  Volume: 181(3) Pages: 1034-43
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer.2012
- Author(s)
  Takeuchi S, Yano S, et al.
- Journal Title
  
  Am J Pathol
  
  Volume: 181(3) Pages: 1034-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Endoscopic findings of upper gastrointestinal lesions in patients with pancreatic cancer.2012
- Author(s)
  Ohtsubo K, Yano S, et al.
- Journal Title
  
  JOP
  
  Volume: 13(4) Pages: 420-6
- DOI
  10.6092/1590-8577/749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390209, KAKENHI-PLANNED-22112010
[Journal Article] Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR mutant lung cancer by decreasing client protein expression and angiogenesis2012
- Author(s)
  Koizumi H, Yano S, et al
- Journal Title
  
  J Thorac Oncol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] E7050, a Met kinase inhibitor, reverses three different mechanisms of hepatocyte growth factor-induced resistance to tyrosine kinase inhibitorsin EGFR mutant lung cancer cells2012
- Author(s)
  Wang W, Li Q, Takeuchi S, Yamada T, Koizumi H, Nakamura T, Matsumoto K, Mukaida N, Nishioka Y, Sone S, Uenaka T, Yano S
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 18 Pages: 1663-1671
- DOI
  10.1158/1078-0432.ccr-11-1171
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790327, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903, KAKENHI-PROJECT-24300329, KAKENHI-PROJECT-24390209, KAKENHI-PROJECT-24390210
[Journal Article] Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor-resistance in EML4-ALK lung cancer cells.2012
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(13) Pages: 3592-602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor-resistance in EML4-ALK lung cancer cells2012
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 13 Pages: 3592-602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] Therapeutic antitumor efficacy of anti-epidermal growth factor receptorantibody, cetuximab, against malignant pleural mesothelioma.2012
- Author(s)
  Kurai J, Chikumi HT, Hamada H, Yano S, , Hashimoto K, Takata M, Sako T, Yamaguchi K, Kinoshita N, Watanabe M, Touge H, Makino H, Igishi Shimizu E
- Journal Title
  
  Int J Oncol
  
  Volume: 41 Pages: 1610-1618
- DOI
  10.3892/ijo.2012.1607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590863, KAKENHI-PROJECT-24390209, KAKENHI-PLANNED-22112010
[Journal Article] Ligand-triggered resistance to molecular targeted drugs in lung cancer: roles of HGF and EGFR ligands2012
- Author(s)
  Yano S, Takeuchi S, Nakagawa T, Yamada T
- Journal Title
  
  Cancer Sci.
  
  Volume: (In press) Pages: 1189-1194
- DOI
  10.1111/j.1349-7006.2012.02279.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] Dual inhibition of Met kinase and angiogenesis to overcome HGF-induced EGFR-TKI resistance in EGFR mutant lung cancer2012
- Author(s)
  Takeuchi S, Yano S, et al.
- Journal Title
  
  Am J Pathol
  
  Volume: 3 Pages: 1034-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor-resistance in EML4-ALK lung cancer cells.2012
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 18(13) Pages: 3592-602
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR mutant lung cancer.2012
- Author(s)
  Nakagawa T,Yano S, et al.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 11(10) Pages: 2149-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390209
[Journal Article] Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor-induced Tyrosine Kinase Inhibitor Resistance in EGFR Mutant Lung Cancer2012
- Author(s)
  Wang W, Yano S, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 6 Pages: 1663-71
- NAID
  120003830985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR mutant lung cancer by decreasing client protein expression and angiogenesis2012
- Author(s)
  Koizumi H, Yano S, et al.
- Journal Title
  
  J Thorac Oncol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Epithelioid glioblastoma changed to typical glioblastoma-the methylation status of MGMT promoter and 5-ALA fluorescence-.2011
- Author(s)
  Tanaka S, Yano S, et al.
- Journal Title
  
  Brain Tumor Pathol
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts.2011
- Author(s)
  Shiirevnyamba A, Yano S, et al.
- Journal Title
  
  Br J Cancer
  
  Volume: 104 Pages: 505-513
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.2011
- Author(s)
  Donev IS, Yano S, et al.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: (掲載確定(印刷中))
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22112001
[Journal Article] Pleural mesothelioma instigates tumor associated fibroblasts to promote progression via malignant cytokine network2011
- Author(s)
  Li Q, Yasumoto K, Yano S, et al.
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 1483-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] HGF-MET in resistance to EGFR tyrosine kinase inhibitors in lung cancer. Hepatocyte growth factor and its receptor signaling and the therapeutic implications.2011
- Author(s)
  Yano S, et al.
- Journal Title
  
  Curr Signal Transd T (in press)
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] A multi-institutional phase II study of combination chemotherapy with S-1 plus cisplatin in patients with advanced non-small cell lung cancer.2011
- Author(s)
  Tomimoto H, Yano S, et al.
- Journal Title
  
  Oncology Letter
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.2011
- Author(s)
  Donev IS, Wang W, Yamada T, Li Q, Takeuchi S, Matsumoto K, Yamori T, Nishioka Y, Sone S, Yano S
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Pages: 2260-2269
- DOI
  10.1158/1078-0432.ccr-10-1993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22240092, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] Pleural mesothelioma instigates tumor associated fibroblasts to promote progression via malignant cytokine network2011
- Author(s)
  Li Q, Wang W, Yamada T, Matsumoto K, Bando Y, Uehara H, Nishioka Y, Sone S, Iwakiri S, Itoi K, Utsugi T, Yano S.
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 1483-1493
- DOI
  10.1016/j.ajpath.2011.05.060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23659434, KAKENHI-PROJECT-23790221, KAKENHI-PROJECT-23790902
[Journal Article] A multi-institutional phase II study of combination chemotherapy with S-1 plus cisplatin in patients with advanced non-small cell lung cancer2011
- Author(s)
  Tomimoto H, Yano S, et al.
- Journal Title
  
  Oncology Letter
  
  Volume: 2 Pages: 465-470
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] The EGFR ligands amphiregulin and heparin-binding EGF-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.2011
- Author(s)
  Yasumoto K, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Reaction of plasma hepatocyte growth factor level in lung cancer patients treated with EGFR-TKIs2011
- Author(s)
  Tanaka H, Kimura T, Kudoh S, Mitsuoka S, Watanabe T, Suzumura T, Tachibana K, Noguchi M, Yano S, Hirata K.
- Journal Title
  
  Int J Cancer
  
  Volume: 126 Pages: 1410-1416
- DOI
  10.1002/ijc.25799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010
[Journal Article] H Uehara Enhancement of osteoclastgenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts British2011
- Author(s)
  Shiirevnyamba A, Yano S, et al.
- Journal Title
  
  British Journal of Cancer
  
  Volume: 104 Pages: 505-513
- DOI
  10.1038/sj.bjc.6606070
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PROJECT-21390442, KAKENHI-PROJECT-23592380
[Journal Article] Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2 expressing small cell lung cancer2011
- Author(s)
  Yamada T, Bando H, Takeuchi S, Kita K, Li Q, Wang W, Akinaga S, Nishioka Y, Sone S, Yano S.
- Journal Title
  
  Cancer Sci
  
  Volume: 102 Pages: 2157-2163
- DOI
  10.1111/j.1349-7006.2011.02093.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] Antiangiogenic therapies for malignant pleural mesothelioma.2011
- Author(s)
  Yano S, et al.
- Journal Title
  
  Front Biosci 16
  
  Pages: 740-748
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] The EGFR ligands amphiregulin and heparin-binding EGF-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer.2011
- Author(s)
  Yasumoto K, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] E7080 suppresses hematogenous multiple organ metastases of lung cancer cells with nonmutated epidermal growth factor recepto2011
- Author(s)
  Ogino H, Hanibuchi M, Kakiuchi S, Trung Van The, Goto H, Ikuta K, Yamada T, Uehara H, Tsuruoka A, Uenaka T, Wang W, Li Q, Takeuchi S, Yano S, Nishioka Y, Sone S.
- Journal Title
  
  Mol Cancer The
  
  Volume: 10 Pages: 1218-1228
- DOI
  10.1158/1535-7163.mct-10-0707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-22390166, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts2011
- Author(s)
  Shiirevnyamba A, Yano S, et al
- Journal Title
  
  Br J Cancer
  
  Volume: 104 Pages: 505-513
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Epithelioid glioblastoma changed to typical glioblastoma-the methylation status of MGMT promoter and 5-ALA fluorescence2011
- Author(s)
  Tanaka S, Yano S, et al.
- Journal Title
  
  Brain Tumor Pathol
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Transient P13K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.2011
- Author(s)
  Donev IS, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17(In press) Pages: 2260-2269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Transient PI3K inhibition induces apoptosis and overcomes HGF-mediated resistance to EGFR-TKIs in EGFR mutant lung cancer.2011
- Author(s)
  Donev IS, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 17 Pages: 2260-2269
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] EGFR ligands, Amphiregulin and Heparin-binding EGF-like Growth Factor Promote Peritoneal Carcinomatosis in CXCR4-expressing Gastric Cancer.2011
- Author(s)
  Yasumoto K, Yano S, et al.
- Journal Title
  
  Clin Cancer Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] A multi-institutional phase II study of combination chemotherapy with S-1 plus cisplatin in patients with advanced non-small cell lung cancer2011
- Author(s)
  Tomimoto H, Yano S, et al
- Journal Title
  
  Oncology Letter
  
  Volume: 2 Pages: 465-470
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Transient PI3K Inhibition Induces Apoptosis and Overcomes HGF-Mediated Resistance to EGFR-TKIs in EGFR Mutant Lung Cancer.2011
- Author(s)
  Donev IS, Yano S, et al.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 2260-2269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] A multi-institutional phase II study of combination chemotherapy with S-1 plus cisplatin in patients with advanced non-small cell lung cancer.2011
- Author(s)
  Tomimoto H, Yano S, et al.
- Journal Title
  
  Oncology Letter
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Reaction of plasma hepatocyte growth factor level in lung cancer patients treated with EGFR-TKIs.2011
- Author(s)
  Tanaka H, Yano S, et al.
- Journal Title
  
  Int J Cancer
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] The EGFR ligands amphiregulin and HB-EGF promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer2011
- Author(s)
  Yasumoto K, Yamada T, Kawashima A, Wang W, Li Q, Donev IS, Takeuchi S, Mouri H, Yamashita K, Ohtsubo K, Yano S.
- Journal Title
  
  Clinical Cancer Research
  
  Volume: 17 Pages: 3619-30
- DOI
  10.1158/1078-0432.ccr-10-2475
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-ORGANIZER-22112001, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23591921, KAKENHI-PROJECT-23790902
[Journal Article] The expression of ki-67, but not proliferating cell nuclear antigen, predicts poor disease free survival in patients with adenocarcinomaof the lung2011
- Author(s)
  Yano S, Yamada T, Takeuchi S, Tachibana K, Minami Y, Yatabe Y, Mitsudomi T, Tanaka H, Kimura T, Kudoh S, Nokihara H, Ohe Y, Yokota J, Uramoto U, Yasumoto Y, Kiura K, Higashiyama M, Oda M, Saito H, Yoshida J, Kondoh K, Noguchi M.
- Journal Title
  
  Anticancer Res
  
  Volume: 6 Pages: 2011-2017
- DOI
  10.1097/jto.0b013e31823ab0dd
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PROJECT-21591831, KAKENHI-PLANNED-22112010, KAKENHI-PROJECT-23790902, KAKENHI-PROJECT-23790903
[Journal Article] The EGFR ligands amphiregulin and heparin-binding EGF-like growth factor promote peritoneal carcinomatosis in CXCR4-expressing gastric cancer2011
- Author(s)
  Yasumoto K, Yano S, et al.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 17 Pages: 3619-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591921
[Journal Article] Reaction of plasma hepatocyte growth factor level in lung cancer patients treated with EGFR-TKIs.2010
- Author(s)
  Tanaka H, Yano S, et al.
- Journal Title
  
  Int J Cancer
  
  Volume: (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] The molecular mechanisms of gastric cancer metastasis : Role of the chemokine receptor CXCR4 and its ligand CXCL12 in peritoneal carcinomatosis.2010
- Author(s)
  Yasumoto K, Yano S.
- Journal Title
  
  Transworld Research Network 37
  
  Pages: 103-113
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] The role of percutaneous needle biopsy in differentiation of renal tumors.2010
- Author(s)
  Izumi K, Yano S, et al.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 40 Pages: 1081-1086
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Hepatocyte growth factor reduces susceptibility to irreversible epidermal growth factor receptor inhibitor in EGFR-T790M lung cancer.2010
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Clin Cancer Res 16
  
  Pages: 174-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Gender difference in bone metastasis of human small cell lung cancer, SBC-5 cells in natural killer-cell depleted severe combined immunodeficient mice2010
- Author(s)
  Sakaguchi S, Goto H, Hanibuchi M, Otsuka S, Ogino H, Kakiuchi S, Uehara H, Yano S, Nishioka Y, Sone S
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 27 Pages: 351-359
- DOI
  10.1007/s10585-010-9333-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256, KAKENHI-PROJECT-22390166
[Journal Article] The role of percutaneous needle biopsy in differentiation of renal tumors.2010
- Author(s)
  Izumi K, Yano S, et al.
- Journal Title
  
  Jpn J Clin Oncol
  
  Volume: 40 Pages: 1081-1086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Enhancement of osteoclastogenic activity in osteolytic prostate cancer cells by physical contact with osteoblasts.2010
- Author(s)
  Shiirevnyamba A, Yano S, et al.
- Journal Title
  
  Br J Cancer
  
  Volume: 104 Pages: 505-513
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Hepatocyte growth factor reduces susceptibility to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.2010
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 174-183
- NAID
  120001939468
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Metastatic renal cell carcinoma complicated with diffuse alveolar hemorrhage : a rare adverse effect of sunitinib.2010
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 15 Pages: 638-641
- NAID
  10027665563
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Hepatocyte growth factor reduces susceptibility to irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer2010
- Author(s)
  Yamada T, Matsumoto K, Wang W, Li Q, NishiokaY, Sekido Y, Sone S, Yano S.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 174-83
- DOI
  10.1158/1078-0432.ccr-09-1204
- NAID
  120001939468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] The molecular mechanisms of gastric cancer metastases : Role of the themokine receptor CXCR4 and its ligand CXCL12 in peritoneal carcinomatosis2010
- Author(s)
  Kazuo Yasumoto, Seiji Yano
- Journal Title
  
  Transworld Research Network
  
  Volume: 37,661(2) Pages: 103-113
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Epidemiological and clinical features of lung cancer patients from 1999 to 2009 in Tokushima Prefecture of Japan.2010
- Author(s)
  Kanematsu T, Yano S, et al.
- Journal Title
  
  J Med Invest
  
  Volume: 57 Pages: 326-333
- NAID
  130004465225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Hepatocvte growth factor reduces susceptibility to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.2010
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 174-183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Epidemiological and clinical features of lung cancer patients from 1999 to 2009 in Tokushima Prefecture of Japan.2010
- Author(s)
  Kanematsu T, Yano S, et al.
- Journal Title
  
  J Med Invest
  
  Volume: 57 Pages: 326-333
- NAID
  130004465225
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Gender difference in bone metastasis of human small cell lung cancer, SBC-5 cells in natural killer-cell depleted severe combined immunodeficient mice.2010
- Author(s)
  Sakaguchi S, Yano S, et al.
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 27 Pages: 351-359
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22112010
[Journal Article] Hepatocyte growth factor reduces susceptibility to an irreversible epidermal growth factor receptor inhibitor in EGFR-T790M mutant lung cancer.2010
- Author(s)
  Yamada T, Matsumoto K, Wang W, Li Q, Nishioka Y, Sekido Y, Sone S, Yano S.
- Journal Title
  
  Clin Cancer Res 16
  
  Pages: 174-183
- NAID
  120001939468
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Metastatic renal cell carcinoma complicated with diffuse alveolar hemorrhage : a rare adverse effect of sunitinib.2010
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 15 Pages: 638-641
- NAID
  10027665563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Gender difference in bone metastasis of human small cell lung cancer, SBC-5 cells in natural killer-cell depleted severe combined immunodeficient mice.2010
- Author(s)
  Sakaguchi S, Yano S, et al.
- Journal Title
  
  Clin Exp Metastasis
  
  Volume: 27 Pages: 351-359
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Metastatic renal cell carcinoma complicated with diffuse alveolar hemorrhage : a rare adverse effect of sunitinib.2010
- Author(s)
  Yamada T, Yasumoto K, Yano S, et al.
- Journal Title
  
  Int J Clin Oncol 15
  
  Pages: 638-641
- NAID
  10027665563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Crosstalk to stromal fibroblasts induces resistance of lung cancer to EGFR tyrosine kinase inhibitors2009
- Author(s)
  Wang W, Li Q, Yamada T, Matsumoto K, Matsumoto I, Oda M, Watanabe G, Kayano Y, Nishioka Y, Sone S, Yano S
- Journal Title
  
  Clin Cancer Res
  
  Volume: 15 Pages: 6630-8
- DOI
  10.1158/1078-0432.ccr-09-1001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Intensification therapy with anti-parathyroid hormonerelated protein antibody plus zoledronic acid for bone metastases of small cell lung cancer cells in severe combined immunodeficient mice.2009
- Author(s)
  Yamada T, Muguruma H, Yano S, Ikuta K, Ogino H, Kakiuchi S, Hanibuchi M, Uehara H, Nishioka Y, Sone S.
- Journal Title
  
  Mol Cancer Ther 8
  
  Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] A Bone metastasis model with osteolytic and osteoblastic properties of human lung cancer ACC-LC-319/bone2 in natural killer cell-depleted severe combined immunodeficient mice.2009
- Author(s)
  Otsuka S, Hanibuchi M, Ikuta K, Yano S, Goto H, Ogino H, Yamada T, Kakiuchi S, Nishioka Y, Takahashi T, Sone S.
- Journal Title
  
  Oncol Res 17
  
  Pages: 581-591
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.2009
- Author(s)
  Ikuta K, Yano S, Trung VT, Hanibuchi M, Goto H, Li Q, Wang W, Yamada T, Ogino H, Kakiuchi S, Uehara H, Sekido Y, Uenaka T, Nishioka Y, Sone S.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 7229-7237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangio-genic cytokine production profiles2009
- Author(s)
  Ikuta K, Yano S, Trung TV, Hanibuchi M, Goto H, Li Q, Wang W, Yamada T, Ogino H, Kakiuchi S, Uehara H, Sekido Y, Uenaka T, Nishioka Y, Sone S
- Journal Title
  
  Clin Cancer Res
  
  Volume: 15 Pages: 7229-37
- DOI
  10.1158/1078-0432.ccr-09-1980
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Novel osteoblastic bone metastasis model with osteolytic changes for lung cancer in natural killer-cell depleted SCID mice.2009
- Author(s)
  Ohtsuka S, Yano S, et al.
- Journal Title
  
  Oncol Res (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Combined chemotherapy with carboplatin plus irinotecan showed favo-rable efficacy in a case with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis.2009
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Int J Clin Oncol (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] E7080, a multi-tyrosine kinase inhibitor, suppresses the progression of malignant pleural mesothelioma with different proangiogenic cytokine production profiles.2009
- Author(s)
  Ikuta K, Yano S
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 7229-7237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Intensification therapy of anti-parathyroid hormone-related protein antibody combined with zoledronic acid for bone metastasis of small cell lung cancer cells in severe combined immunodeficient mice2009
- Author(s)
  Yamada T, Muguruma H, Yano S, Ikuta K, Ogino H, Kakiuchi S, Hanibuchi M, Uehara H, Nishioka Y, Sone S
- Journal Title
  
  Mol Cancer Ther 8
  
  Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Intensification therapy with anti-para-thyroid hormonerelated protein antibody plus zoledronic acid for bone metastases of small cell lung cancer cells in SCID mice2009
- Author(s)
  Yamada T, Muguruma H, Yano S, Ikuta K, Ogino H, Kakiuchi S, Hanibuchi M, Uehara H, Nishioka Y, Sone S.
- Journal Title
  
  Mol Cancer Ther
  
  Volume: 8 Pages: 119-26
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/19139120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390256
[Journal Article] Crosstalk to stromal fibroblasts induces resistance of lung cancer to EGFR tyrosine kinase inhibitors.2009
- Author(s)
  Wang W, Yano S, et al.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 6630-6638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Crosstalk to stromal fibroblasts induces resistance of lung cancer to epidermal growth factor receptor tyrosine kinase inhibitors2009
- Author(s)
  Wang W, Li Q, Yamada T, Matsumoto K, Matsumoto I, Oda M, Watanabe G, Kayano Y, Nishioka Y, Sone S, Yano S.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 6630-6638
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a patient with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis.2009
- Author(s)
  Yamada T, Yasumoto K, Yano S.
- Journal Title
  
  Int J Clin Oncol 14
  
  Pages: 468-472
- NAID
  10027201066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma cells with EGF receptor mutations.2008
- Author(s)
  Yano S, et al.
- Journal Title
  
  Cancer Res 68
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.2008
- Author(s)
  Ogino H, Yano S, et al.
- Journal Title
  
  Cancer Letter 265
  
  Pages: 55-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.2008
- Author(s)
  Ogino H, Yano S, Kakiuchi S, Yamada T, Ikuta K, Nakataki E, Goto H, Hanibuchi M, Nishioka Y, Ryan A, Sone S.
- Journal Title
  
  Cancer Letters 265
  
  Pages: 55-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Follistatin suppresses the production of experimental multiple-organ metast-asis by small cell lung cancer cells in NK cell-depleted SCID mice.2008
- Author(s)
  Ogino H, Yano S, et al.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor-activating mutations.2008
- Author(s)
  Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakmura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S.
- Journal Title
  
  Cancer Res 68
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Lysophosphoatidic acid stimulated proliferation and motility of malignant pleural mesothelioma cells through LPA receptors, LPA_1 and LPA_22008
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1603-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Intensification therapy of anti-parathyroid hormone-related protein anti-body combined with zoledronic acid for bone metastasis of small cell lung cancer cells in severe combined immunodeficient mice.2008
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Mol Cancer Ther 8
  
  Pages: 119-126
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in natural killer cell-depleted SCID mice.2008
- Author(s)
  Ogino H, Yano S, Kakiuchi S, Muguruma H, Ikuta K, Hanibuchi M, Uehara H, Tsuchida K, Sugino H, Sone S.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma cells with EGF receptor mutations.2008
- Author(s)
  Yano S, Wang W, et al.
- Journal Title
  
  Cancer Res 66
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma with epidermal growth factor receptor activating mutations2008
- Author(s)
  Yano S., et.al.
- Journal Title
  
  Cancer Res. 68
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement.2008
- Author(s)
  Ogino H, Yano S, et al.
- Journal Title
  
  Cancer Letter 265
  
  Pages: 55-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Hepatocyte growth factor induces gefitinib resistance of lung adenocarcinoma cells with EGF receptor mutations2008
- Author(s)
  Yano S, Wang W, Li Q, Matsumoto K, Sakurama H, Nakamura T, Ogino H, Kakiuchi S, Hanibuchi M, Nishioka Y, Uehara H, Mitsudomi T, Yatabe Y, Nakamura T, Sone S
- Journal Title
  
  Cancer Res 68
  
  Pages: 9479-9487
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Novel dual targeting strategy with vandetanib induces tumor cell apoptosis and inhibits angiogenesis in malignant pleural mesothelioma cells expressing RET oncogenic rearrangement2008
- Author(s)
  Ogino H, Yano S, Kakiuchi S, Yamada T, Ikuta K, Nakataki E, Goto H, Nishioka Y, Ryan A, Sone S
- Journal Title
  
  Cancer Letter 265
  
  Pages: 55-66
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in NK cell-depleted SCID mice2008
- Author(s)
  Ogino H, Yano S, Kakiuchi S, Muguruma H, Ikuta K, Uehara H, Tsuchida K, Sugino H, Sone S
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Follistatin suppresses the production of experimental multiple-organ metastasis by small cell lung cancer cells in NK cell-depleted SCID mice.2008
- Author(s)
  Ogino H, Yano S, et al.
- Journal Title
  
  Clin Cancer Res 14
  
  Pages: 660-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.2008
- Author(s)
  Yamada T, Yano S, Ogino H, Ikuta K, Kakiuchi S, Hanibuchi M, Kanematsu T, Taniguchi T, Sekido Y, Sone S.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1603-1610
- NAID
  10024009864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2.2008
- Author(s)
  Yamada T, Yano S, et al.
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1603-1610
- NAID
  10024009864
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591565
[Journal Article] Lysophosphoatidic acid stimulated proliferation and motility of malignant pleural mesothelioma cells through LPA receptors, LPA_1 and LPA_<2->2008
- Author(s)
  Yamada T, Yano S, Ogino H, Ikuta K, Kakiuchi S, Hanibuchi M, Taniguchi, Sekido Y, Sone S
- Journal Title
  
  Cancer Sci 99
  
  Pages: 1603-1610
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Molecular pathogenesis and its therapeutic modalities of lung cancer metastasis to bone.2007
- Author(s)
  Sone S, Yano S.
- Journal Title
  
  Cancer Metastasis Rev 26
  
  Pages: 685-289
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] The therapeutic efficacy of anti-vascular endothelial growth factor antibody, bevacizumab, and pemetrexed against orthotopically implanted human pleural mesothelioma cells in SCID mice.2007
- Author(s)
  Li Q, Yano S, Ogino H, Wang W, Uehara H, Nishioka Y, Sone S.
- Journal Title
  
  Clin Cancer Res 13
  
  Pages: 5918-5925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Novel orthotopic implantation model of human malignant pleural mesothelioma (EHMES-10 cells) highly expressing vascular endothelial growth factor and its receptor.2006
- Author(s)
  Nakataki E, Yano S, Matsumori Y, Goto H, Kakiuchi S, Muguruma H, Bando Y, Uehara H, Hamada H, Kito E, Yokoyama A, Sone S.
- Journal Title
  
  Cancer Sci 97
  
  Pages: 183-191
- NAID
  10018177286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Current status and perspective of angiogenesis and antivascular therapeutic strategy : non-small cell lung cancer.2006
- Author(s)
  Yano S, et al.
- Journal Title
  
  Int J Clin Oncol 11
  
  Pages: 73-81
- NAID
  10018174594
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590792
[Journal Article] Current status and perspective of angiogenesis and antivascular therapeutic strategy : non-small cell lung cancer.2006
- Author(s)
  Yano S
- Journal Title
  
  Int J Clin Oncol 11・2
  
  Pages: 73-82
- NAID
  10018174594
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590792
[Journal Article] Current status and persoective of angiogenesis and antivascular therapeutic strategy : non-small cell lung cancer.2006
- Author(s)
  Yano, S.
- Journal Title
  
  Int J Clin Oncol 11・2
  
  Pages: 73-81
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] ZD6474, an inhibitor of vascular endothelial growth factor receptor tyrosine kinase, inhibits growth of experimental lung metastasis and production of malignant pleural effusions in a non-small cell lung cancer model.2006
- Author(s)
  Matsumori Y, Yano S, Goto H, Nakataki E, Wedge SR, Ryan AJ, Sone S.
- Journal Title
  
  Oncol Res 16
  
  Pages: 15-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice.2005
- Author(s)
  Yano, S.
- Journal Title
  
  Clin.Cancer Res. 11・24
  
  Pages: 8789-8798
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Colon cancer cell-derived high mobility group 1/amphoterin induces growth inhibition and apoptosis in macrophages.2005
- Author(s)
  Kuniyasu H, Yano S, Sasaki T, Sasahira T, Sone S, Ohmori H.
- Journal Title
  
  Am J Pathol 166
  
  Pages: 751-759
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Antitumor vascular strategy for controlling experimental metastatic spread of human small cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficiency mice.2005
- Author(s)
  Yano S
- Journal Title
  
  Clin Cancer Res 11・24
  
  Pages: 8789-8798
- Data Source
  KAKENHI-PROJECT-17590792
[Journal Article] Antitumor vascular strategy for controlling experimental metastatic spread of human small-cell lung cancer cells with ZD6474 in natural killer cell-depleted severe combined immunodeficient mice.2005
- Author(s)
  Yano S, Muguruma H, Matsumori Y, Goto H, Nakataki E, Edakuni N, Tomimoto H, Kakiuchi S, Yamamoto A, Uehara H, Ryan A, Sone S.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 8789-8798
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Re-treatment of lung adenocarcinoma patients with gefitinib who had experienced favorable results from their initial treatment with this selective epidermal growth factor receptor inhibitor : a report of three cases.2005
- Author(s)
  Yano, S.
- Journal Title
  
  Oncol.Res. 15・2
  
  Pages: 107-111
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Re-treatment of lung adenocarcinoma patients with gefitinib who had experienced favorable results from their initial treatment with this selective epidermal growth factor receptor inhibitor : a report of three cases.2005
- Author(s)
  Yano S
- Journal Title
  
  Oncol Res 15・2
  
  Pages: 107-111
- Data Source
  KAKENHI-PROJECT-17590792
[Journal Article] Reveromycin A inhibits osteolytic bone metastasis of small-cell lung cancer cells, SBC-5, through an antiosteoclastic activity.2005
- Author(s)
  Muguruma H, Yano S, Kakiuchi S, Uehara H, Kawatani M, Osada H, Sone S.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 8822-8828
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17016051
[Journal Article] Novel osteoblastic bone metastasis model with osteolytic changes for lung cancer in natural killer-cell depleted SCID mice
- Author(s)
  Otsuka S, Yano S, Hanibuchi M, Ikuta K, Ogino H, Yamada T, Kakiuchi S, Sone S
- Journal Title
  
  Oncol Res (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Combined chemotherapy with carboplatin plus irinotecan showed favorable efficacy in a case with relapsed small cell carcinoma of the prostate complicated with meningeal carcinomatosis
- Author(s)
  Yamada T, Ohtsubo K, Mouri H, Yamashita K, Yasumoto K, Izumi K, Zen Y, Watanabe H, Yano S
- Journal Title
  
  Int J Clin Oncol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590900
[Journal Article] Re-treatment of lung adenocarcinoma patients with gefitinib who had experienced favorable results from their initial treatment with this selective epidermalgrowth factor receptor inhibitor : a report of three cases.
- Author(s)
  Yano, S.
- Journal Title
  
  Oncol Res. (in press)
- Data Source
  KAKENHI-PROJECT-12217099
[Patent] 肺癌患者の治療の有効性の予測検査方法及び肺癌治療剤のスクリーニング方法2013
- Inventor(s)
  矢野聖二、竹内伸司、中川学之
- Industrial Property Rights Holder
  矢野聖二、竹内伸司、中川学之
- Industrial Property Rights Type
  特許
- Filing Date
  2013-03-04
- Data Source
  KAKENHI-PLANNED-22112010
[Patent] 肺癌患者の治療の有効性の予測検査方法及び肺癌治療剤のスクリーニング方法2013
- Inventor(s)
  矢野聖二、竹内伸司、中川学之
- Industrial Property Rights Holder
  矢野聖二、竹内伸司、中川学之
- Filing Date
  2013-03-04
- Data Source
  KAKENHI-PROJECT-24390209
[Patent] 分子標的薬に対する感受性が低下している癌の治療薬および分子標的薬に対する感受性を増強する医薬組成物2009
- Inventor(s)
  矢野聖二、松本邦夫
- Industrial Property Rights Holder
  金沢大学
- Industrial Property Number
  2009-078621
- Filing Date
  2009-03-27
- Acquisition Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-17016051
[Patent] 分子標的薬に対する感受性が低下している癌の治療薬および分子標的薬に対する感受性を増強する医薬組成物2009
- Inventor(s)
  矢野聖二、松本邦夫
- Industrial Property Rights Holder
  矢野聖二、松本邦夫
- Filing Date
  2009-10-09
- Overseas
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] 第二世代TRK阻害薬の耐性機構解明と耐性克服治療の探索.2021
- Author(s)
  鈴木千晶, 矢野聖二,他.
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] 分子標的薬抵抗性・耐性の治療標的.2021
- Author(s)
  矢野聖二.
- Organizer
  第62回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] ALK 融合遺伝子陽性肺癌における STAT3 阻害薬の併用によるアポトーシス抵抗性の克服.2021
- Author(s)
  柳村尚寛, 矢野聖二,他.
- Organizer
  第25回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Resistance to targeted therapy stratified with oncogenes or tumor suppressor genes.2021
- Author(s)
  谷本　梓, 矢野聖二.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Heterogeneity and drug resistance2021
- Author(s)
  Seiji Yano
- Organizer
  Wourld Conference on Lung Cancer 2020
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Circumvention of targeted drug tolerance of lung cancer.2020
- Author(s)
  矢野聖二
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] 研究が切り拓く肺がん治療の最前線2020
- Author(s)
  矢野聖二
- Organizer
  第36回日本癌学会市民公開講座
- Invited
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Circumvention of targeted drug tolerance in EGFR mutated lung cancer.2019
- Author(s)
  矢野　聖二
- Organizer
  第60回日本肺癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Circumvention of targeted drug resistance in lung cancer.2019
- Author(s)
  Yano S.
- Organizer
  The Joint Symposium Microenvironment and Precision Oncology.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Circumvention of targeted drug tolerance in lung cancer.2019
- Author(s)
  Yano S.
- Organizer
  International Symposium on Tumor Biology in Kanazawa 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Drug-tolerant persister cells and AXL.2019
- Author(s)
  Yano S.
- Organizer
  The 24th JFCR-ISCC
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] 肺がんの治療抵抗性メカニズムの最新情報.2019
- Author(s)
  矢野　聖二
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Mechanisms of drug tolerant cells to osimertinib in EGFR mutated lung cancer.2019
- Author(s)
  矢野　聖二
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Mechanism of the intrinsic resistance and emergence of tolerant cells to osimertinib in EGFR mutated lung cancer.2019
- Author(s)
  Yano S.
- Organizer
  11th AACR-JCA Joint Conference on Breakthroughs in Cancer Research: Biology to Precision Medicine.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03665
[Presentation] Inter-Organ Heterogeneity on Mechanisms of Targeted Drug Resistance-Central Nervous System (CNS) vs Extra CNS-.2018
- Author(s)
  Yano S.
- Organizer
  IASLC 19th World Conference on Lung Cancer. (WCLC)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] Foretinib circumvents the NTRK1 G667C mutation-associated entrectinib-resistance in the brain and liver metastases produced by NTRK1 fusion-positive tumor cells.2018
- Author(s)
  Yano S.
- Organizer
  10.European Society for Medical Oncology (ESMO) 2018 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] Inter-Organ Heterogeneity on Mechanisms of Targeted Drug Resistance-Central Nervous System (CNS) vs Extra CNS-.2018
- Author(s)
  Yano S.
- Organizer
  The 6th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] 分子標的薬の獲得耐性と耐性克服治療.2017
- Author(s)
  矢野聖二.
- Organizer
  第15回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] SSP基礎講座・もっと知りたい分子標的薬.2017
- Author(s)
  矢野聖二.
- Organizer
  第76回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] NTRK1遺伝子異常を有する大腸癌細胞株におけるTRK阻害薬Entrectinib耐性機構の解明とその克服.2017
- Author(s)
  西山明宏,矢野聖二,他.
- Organizer
  第26回日本がん転移学会学術集会総会
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] Challenge to overcome targeted drug resistance.2017
- Author(s)
  Yano S.
- Organizer
  5.Kanazawa University Cancer Research Institute the 50th Anniversary International Symposium 2017.
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] 肺がんの新規分子標的治療を開発するトランスレーショナルリサーチ.2017
- Author(s)
  矢野聖二.
- Organizer
  第57回日本呼吸器学会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] 肺がんの髄膜がん腫症とEGFR-TKI耐性.2016
- Author(s)
  矢野聖二,　新井祥子,　福田康二,　山田忠明,　竹内伸司,　南條成輝,　片上信之,　岡田保典.
- Organizer
  第25回日本がん転移学会学術集会総会
- Place of Presentation
  米子市
- Invited
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] Characterization of cancer stromal fibroblasts in primary sites of metastatic gastric cancer2016
- Author(s)
  安本　和生、川島　篤弘、葛西　傑、矢野　聖二、元雄　良治
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-26461972
[Presentation] Met copy number gain associates with gefitinib resistance in leptomeningeal carcinomatosis of EGFR mutant lung cancer.2016
- Author(s)
  Yano S.
- Organizer
  The 17th World Conference on Lung Cancer (WCLC 2016)
- Place of Presentation
  Wienna
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05308
[Presentation] HDAC inhibition overcomes crizotinib-resistance by inducing mesenchymal-epithelial reverting transition (MERT) via miR-200c up-regulation in EML4-ALK lung cancer cells.2016
- Author(s)
  Koji Fukuda, Shigeki Nanjo, Shinji Takeuchi, Tadaaki Yamada, Ryohei Katayama, Kengo Takeuchi, Hiroshi Nishihara, Seiji Yano.
- Organizer
  Tenth AACR-JCA Joint Conference
- Place of Presentation
  Maui, Hawaii, USA
- Year and Date
  2016-02-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860603
[Presentation] Bone microenvironment conferes Hsp90 inhibitor resistance in the metastatic small sell lung cancer.2015
- Author(s)
  Yano S.
- Organizer
  Joint International Symposium on TGF-βFamily and Cancer
- Place of Presentation
  International Congress Center EPOCHAL TSUKUBA (Japan)
- Year and Date
  2015-01-12
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Bone microenvironment conferes Hsp90 inhibitor resistance in the metastatic small sell lung cancer.2015
- Author(s)
  Yano S.
- Organizer
  Joint International Symposium on TGF-βFamily and Cancer
- Place of Presentation
  International Congress Center EPOCHAL TSUKUBA (Japan)
- Year and Date
  2015-01-12
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Therapeutic activity of glycoengineered anti-GM2 antibody BIW-8962 against　malignant pleural mesothelioma.2015
- Author(s)
  Yano S.
- Organizer
  15th Annual Targeted Therapies of The Treatment of Lung Cancer
- Place of Presentation
  Hotel Fairmont Miramar Wilshire Boulevard (USA)
- Year and Date
  2015-02-19
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Therapeutic activity of glycoengineered anti-GM2 antibody BIW-8962 against　malignant pleural mesothelioma.2015
- Author(s)
  Yano S.
- Organizer
  15th Annual Targeted Therapies of The Treatment of Lung Cancer
- Place of Presentation
  Hotel Fairmont Miramar　Wilshire Boulevard (USA)
- Year and Date
  2015-02-19
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 肺がんの分子標的治療薬耐性の機構解明と耐性克服治療開発.2014
- Author(s)
  矢野聖二
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  ホテルメトロポリタン仙台
- Year and Date
  2014-06-25
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 肺がんの骨転移のメカニズムと分子標的治療.2014
- Author(s)
  矢野聖二
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール
- Year and Date
  2014-07-10
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 脳転移：腫瘍内科の視点から.2014
- Author(s)
  矢野聖二
- Organizer
  第52回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 肺がんの骨転移のメカニズムと分子標的治療.2014
- Author(s)
  矢野聖二
- Organizer
  第23回日本がん転移学会学術集会・総会
- Place of Presentation
  金沢市文化ホール
- Year and Date
  2014-07-10
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Resistance to EGFR-TKI in EGFR mutant lung cancer.2014
- Author(s)
  矢野聖二
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Resistance to EGFR-TKI in EGFR mutant lung cancer.2014
- Author(s)
  矢野聖二
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-09-25
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 脳転移：腫瘍内科の視点から.2014
- Author(s)
  矢野聖二
- Organizer
  第52回日本癌治療学会学術集会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-08-28
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] 日本における腫瘍内科教育の今後～分子標的薬体制の克服絵を目指した研究を通して～2014
- Author(s)
  矢野聖二
- Organizer
  第111回日本内科学会講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-11
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 日本における腫瘍内科教育の今後～分子標的薬体制の克服絵を目指した研究を通して～2014
- Author(s)
  矢野聖二
- Organizer
  第111回日本内科学会講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2014-04-11
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] 肺がんの分子標的治療薬耐性の機構解明と耐性克服治療開発.2014
- Author(s)
  矢野聖二
- Organizer
  第18回日本がん分子標的治療学会学術集会
- Place of Presentation
  ホテルメトロポリタン仙台
- Year and Date
  2014-06-25
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] 胃癌腹膜播種形成におけるサイトカインからみた分子機構解明と特異的標的療法の開発2013
- Author(s)
  安本　和生　高橋　豊　矢野　聖二
- Organizer
  第108回日本外科学会学術総会
- Place of Presentation
  福岡　博多　マリンメッセ
- Data Source
  KAKENHI-PROJECT-23591921
[Presentation] 胃癌腹膜播種形成におけるサイトカインからみた分子機構の解明と新規特異的な標的治療法の開発<Surgical Science and State of the Art>2013
- Author(s)
  安本和生,矢野聖二
- Organizer
  第113回日本外科学会学術総会
- Place of Presentation
  福岡
- Year and Date
  2013-04-11
- Data Source
  KAKENHI-PROJECT-23591921
[Presentation] METシグナル活性化はスキルス胃癌がん性腹膜炎病態形成に深く関与する2013
- Author(s)
  安本　和生、Zhao Lu、矢野　聖二
- Organizer
  第22回日本がん転移学会学術総会
- Place of Presentation
  長野　松本
- Data Source
  KAKENHI-PROJECT-23591921
[Presentation] METシグナル活性化はスキルス胃癌がん性腹膜炎病態形成に深く関与する2013
- Author(s)
  安本和生,Zhao Lu,矢野聖二
- Organizer
  WS7がん転移の病理
- Place of Presentation
  松本
- Year and Date
  2013-07-11
- Data Source
  KAKENHI-PROJECT-23591921
[Presentation] Resistance to EGFR TKIs2013
- Author(s)
  Seiji Yano
- Organizer
  IASLC 15th World Conference on Lung Cancer
- Place of Presentation
  Convention & Exhibition Centre (Sydney, Australia)
- Invited
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] Ligand-stimulated receptor activation as novel targets to overcome resistance to molecular targeted drugs in lung cancer.2012
- Author(s)
  矢野聖二
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor-resistance in EML4-ALK lung cancer cells.2012
- Author(s)
  Yano S.
- Organizer
  AACR Molecularly Targeted Therapies: Mechanisms of Resistance Conference
- Place of Presentation
  The Westin San Diego
- Year and Date
  2012-05-09
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Paracrine receptor activation by microenvironment triggers bypass survival signals and ALK inhibitor-resistance in EML4-ALK lung cancer cells.2012
- Author(s)
  Yano S.
- Organizer
  AACR Molecularly Targeted Therapies: Mechanisms of Resistance Conference
- Place of Presentation
  The Westin San Diego
- Year and Date
  2012-05-09
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Strategy to Treat EGFR-TKI Resistance in EGFR Mutant Lung Cancer.2012
- Author(s)
  Yano S.
- Organizer
  5th Asia Pacific Lung Cancer Conference(APLCC)
- Place of Presentation
  Hilton Fukuoka Sea Hawk
- Year and Date
  2012-11-26
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Molecular mechanisms of EGFR－TKI resistance and strategy with HGF-Met inhibitors to overcome the resistance.2012
- Author(s)
  矢野聖二
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2012-07-26
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Molecular mechanisms of EGFR- TKI resistance and strategy with HGF-Met inhibitors to overcome the resistance.2012
- Author(s)
  矢野聖二
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2012-07-26
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Ligand-stimulated receptor activation as novel targets to overcome resistance to molecular targeted drugs in lung cancer.2012
- Author(s)
  矢野聖二
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  ロイトン札幌
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Ligand-stimulated receptor activation as novel targets to overcome resistance to molecular targeted drugs in lung cancer2012
- Author(s)
  矢野聖二
- Organizer
  第71回日本癌学会学術集会
- Place of Presentation
  ロイトン札幌（札幌）
- Year and Date
  2012-09-19
- Invited
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] Strategy to Treat EGFR-TKI Resistance in EGFR Mutant Lung Cancer.2012
- Author(s)
  Yano S.
- Organizer
  5th Asia Pacific Lung Cancer Conference.(APLCC)
- Place of Presentation
  Hilton Fukuoka Sea Hawk
- Year and Date
  2012-11-26
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] がん微小環境からみた臓器特異的転移機序の解析ならびに新規標的分子阻害2012
- Author(s)
  安本和生,山田忠明,川島篤弘,矢野聖二
- Organizer
  第21回日本転移学会シンポジウム1 (指定演題)—微小環境からみた臓器特異的がん転移
- Place of Presentation
  広島
- Year and Date
  2012-07-12
- Data Source
  KAKENHI-PROJECT-23591921
[Presentation] がん細胞の環境応答-臨床的立場から2012
- Author(s)
  矢野聖二
- Organizer
  千里ライブサイエンスセミナー「がんの転移・浸潤と微小環境」
- Place of Presentation
  千里ライフサイエンスセンタービル(大阪府豊中市)(招待講演)
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] がん転移のメカニズム2011
- Author(s)
  矢野聖二
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] EGFR ligands induce resistance to ALK inhibitors in EML4-ALK lung cancer cells2011
- Author(s)
  矢野聖二
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] Receptor ligand-triggered resistance to molecular targeted drugs in lung cancer2011
- Author(s)
  矢野聖二
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Hepatocyte growth factor expression in EGFR mutant lung cancer with intrinsic and acquired resistance to tyrosine kinase inhibitors in a Japanese cohort. 2011 American Society of Clinical Oncology(ASCO)2011
- Author(s)
  Yano S, Yamada T, Takeuchi S, Tachibana K, Minami Y, Yatabe Y, Mitsudomi T, Tanaka H, Kimura T, Kudoh S, Nokihara H, Ohe Y, Yokota J, Uramoto H, Yasumoto K, Kiura K, Higashiyama M, Oda M, Saito H, Yoshida J, Kondoh K
- Organizer
  Annual Meeting
- Place of Presentation
  McCormick Place(USA.)
- Year and Date
  2011-06-04
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] ケモカインCXCR4発現胃癌による癌性腹膜炎発症機序の分子生物学的解明ならびに標的治療法の開発2011
- Author(s)
  安本和生、山下要、川島篤弘、矢野聖二
- Organizer
  第66回日本消化器外科学会総会WS10「消化器癌に対する分子生物学の臨床応用(上部消化管)」
- Place of Presentation
  名古屋
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-23591921
[Presentation] HGF-triggered EGFR-TKI resistance in EGFR mutant lung cancer2011
- Author(s)
  矢野聖二
- Organizer
  第9回日本臨床腫瘍学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] がん転移のメカニズム2011
- Author(s)
  矢野聖二
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] Receptor ligand-triggered resistance to molecular targeted drugs in lung cancer2011
- Author(s)
  矢野聖二
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGF-triggered EGFR-TKI resistance in EGFR mutant lung cancer2011
- Author(s)
  矢野聖二
- Organizer
  第9回日本臨床腫瘍学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] EGFR ligands induce resistance to ALK inhibitors in EML4-ALK lung cancer cells2011
- Author(s)
  矢野聖二
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] EGFR遺伝子変異陽性肺がんにおけるEGFR-TKI耐性の克服2010
- Author(s)
  矢野聖二
- Organizer
  第48回日本癌治療学会
- Place of Presentation
  国立京都国際会館(京都)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] HGFによるEGFR-TKI耐性の分子機構解明とその克服に向けた研究2010
- Author(s)
  矢野聖二
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島国際会議場(広島)(篠井・河合賞受賞講演招待講演)
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] EGFR変異肺がんのチロシンキナーゼ阻害薬耐性と治療戦略(シンポジウム)2010
- Author(s)
  矢野聖二
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際コンベンションセンター(大阪府大阪市)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-ORGANIZER-22112001
[Presentation] EGFR肺がんのチロシンキナーゼ阻害薬耐性と治療戦略2010
- Author(s)
  矢野聖二
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] マルチキナーゼ阻害薬を用いた胸膜中皮腫の薬物治療2010
- Author(s)
  矢野聖二
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島国際会議場(広島)
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] 肺がんのEGFR-TKI耐性の分子機構と克服に向けた試み2010
- Author(s)
  矢野聖二
- Organizer
  第14回日本がん分子標的治療学会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2010-07-08
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] 肺がんと骨転移2010
- Author(s)
  矢野聖二
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] EGFR遺伝子変異陽性肺がんにおけるEGFR-TKI耐性の克服2010
- Author(s)
  矢野聖二
- Organizer
  第48回日本癌治療学会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2010-10-28
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] マルチキナーゼ阻害薬を用いた胸膜中皮腫の薬物治療2010
- Author(s)
  矢野聖二
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島国際会議場(広島県)
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] EGFR肺がんのチロシンキナーゼ阻害薬耐性と治療戦略2010
- Author(s)
  矢野聖二
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場,リーガロイヤルホテル大阪(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-20591565
[Presentation] Therapeutic effect of HGF inhibitors against HGF-induced EGFR-TKI resistance in lung cancer harboring EGFR mutations.2010
- Author(s)
  矢野聖二
- Organizer
  第101回AACR
- Place of Presentation
  Walter E.Washington Convention Center(Washington DC)
- Year and Date
  2010-04-18
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] EGFR肺がんのチロシンキナーゼ阻害薬耐性と治療戦略2010
- Author(s)
  矢野聖二
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-23
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGFによる肺癌のEGFR-TKI耐性の分子機構解明とその克服に向けた研究2010
- Author(s)
  矢野聖二
- Organizer
  第51回日本肺癌学会総会
- Place of Presentation
  広島国際会議場(広島県)
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] 肺がんと骨転移2010
- Author(s)
  矢野聖二
- Organizer
  第28回日本骨代謝学会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGFによるEGFR-TKI耐性の分子機構解明とその克服に向けた研究(篠井・河合賞受賞講演)2010
- Author(s)
  矢野聖二
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島国際会議場(広島県) 招待講演
- Year and Date
  2010-11-04
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] EGFR肺がんのチロシンキナーゼ阻害薬耐性と治療戦略2010
- Author(s)
  矢野聖二
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] Hepatocyte growth factor as an inducer of EGFR-TKI resistance in lung cancer harboring EGFR activating mutations2009
- Author(s)
  矢野聖二
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGF induces resistance to EGFR tyrosine kinase, inhibitors in lung cancer with EGFR activating mutations.2009
- Author(s)
  Seiji Yano
- Organizer
  The 14th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  COEX (Seoul, Korea)
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Hepatocyte growth factor as an inducer of EGFR-TKI resistance in lung cancer harboring EGFR activating mutations.2009
- Author(s)
  矢野聖二
- Organizer
  第68回日本癌学会学術総会(International Sessions)
- Place of Presentation
  横浜
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] 肺がんの分子標的薬耐性と微小環境.2009
- Author(s)
  矢野聖二
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  ホテルクレメント徳島(徳島市)
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] HGF induces resistance to EGFR tyrosine kinase inhibitors in lung cancer with EGFR activating mutations2009
- Author(s)
  Yano S
- Organizer
  The 14th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  Convention & Exhibition(Korea)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] Hepatocyte growth factor as an inducer of EGFR-TKI resistance in lung cancer harboring EGFR activating mutations.2009
- Author(s)
  矢野聖二
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] HGF induces resistance to EGFR tyrosine kinase inhibitors in lung cancer with EGFR activating mutations.(招待講演)2009
- Author(s)
  矢野聖二
- Organizer
  The 14th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  Convention and Exibition Center, (Seoul Korea)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGF-MET経路によるEGFR -TKI耐性誘導の分子機構とその克服に向けた戦略.2009
- Author(s)
  矢野聖二
- Organizer
  第50回日本肺癌学会総会(特別セッション)
- Place of Presentation
  東京
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] HGF-MET経路によるEGFR-TKI耐性誘導の分子機構とその克服に向けた戦略2009
- Author(s)
  矢野聖二
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-20591565
[Presentation] Hepatocyte growth factor as an inducer of EGFR-TKI resistance in lung cancer harboring EGFR activating mutations.2009
- Author(s)
  矢野聖二
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-20591565
[Presentation] HGF induces resistance to EGFR tyrosine kinase inhibitors in lung cancer with EGFR activating mutations.2009
- Author(s)
  Yano S.
- Organizer
  The 14th Congress of the Asian Pacific Society of Respirology
- Place of Presentation
  Seoul, Korea
- Year and Date
  2009-11-17
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] Hepatocyte growth factor as an inducer of EGFR-TKI resistance in lung cancer harboring EGFR activating mutations.(招待講演)2009
- Author(s)
  矢野聖二
- Organizer
  第68回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] 肺がんの分子標的薬耐性と微小環境.(招待講演)2009
- Author(s)
  矢野聖二
- Organizer
  第13回日本がん分子標的治療学会学術集会
- Place of Presentation
  ホテルクレメント徳島(徳島市)
- Year and Date
  2009-06-24
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGF-MET経路によるEGFR-TKI耐性誘導の分子機構とその克服に向けた戦略2009
- Author(s)
  矢野聖二
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2009-11-21
- Data Source
  KAKENHI-PROJECT-21390256
[Presentation] HGF-MET経路によるEGFR-TKI耐性誘導の分子機構とその克服に向けた戦略.2009
- Author(s)
  矢野聖二
- Organizer
  第50回日本肺癌学会総会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] マウスモデルによる肺癌多臓器転移の分子機構解析2008
- Author(s)
  矢野聖二
- Organizer
  第97回日本病理学会総会
- Place of Presentation
  金沢市
- Year and Date
  2008-05-16
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] Respiratory year in review : 肺がんの分子標的治療.2008
- Author(s)
  矢野聖二
- Organizer
  第48回日本呼吸器学会総会
- Place of Presentation
  神戸市
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] 肝細胞増殖因子(HGF)はEGFR活性型遺伝子変異を有する肺腺癌のゲフィチニブ耐性を誘導する.2008
- Author(s)
  矢野聖二
- Organizer
  第49回日本肺癌学会総会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] Therapeutic strategy targeting angiogenic factors against pleural mesothelioma2008
- Author(s)
  矢野聖二
- Organizer
  The U.S.-Japan Cooperateive Cancer Research Program Workshop 2008
- Place of Presentation
  京都市平安会館
- Year and Date
  2008-03-20
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] 肝細胞増殖因子(HGF)はEGFR活性型遺伝子変異を有する肺腺癌のゲフィチニブ耐性を誘導する2008
- Author(s)
  矢野聖二、山田忠明、埴淵昌毅、柿内聡司、西岡安彦、光冨徹哉、谷田部恭、曽根三郎
- Organizer
  第49回日本肺癌学会総会
- Place of Presentation
  北九州市
- Year and Date
  2008-11-13
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] Respiratory year in review : 肺がんの分子標的治療2008
- Author(s)
  矢野聖二
- Organizer
  第48回日本呼吸器学会総会
- Place of Presentation
  神戸市
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] EGFR-TKI耐性2008
- Author(s)
  矢野聖二
- Organizer
  第23回日本肺癌学会ワークショップ
- Place of Presentation
  名古屋市
- Year and Date
  2008-07-19
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] Molecular pathogenesis of pleural mesothelioma and its molecular targeted therapy2007
- Author(s)
  矢野聖二
- Organizer
  第66回日本癌学会
- Place of Presentation
  パシフイコ横浜
- Year and Date
  2007-10-04
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] 呼吸器悪性腫瘍とVEGF2007
- Author(s)
  矢野聖二, ら
- Organizer
  第47回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] 呼吸器悪性腫瘍とVEGF.2007
- Author(s)
  矢野聖二, ら
- Organizer
  第47回日本呼吸器学会学術講演会
- Place of Presentation
  東京国際フォーラム
- Year and Date
  2007-05-12
- Data Source
  KAKENHI-PROJECT-17016051
[Presentation] 中皮腫の分子病態と治療の展望2007
- Author(s)
  矢野聖二
- Organizer
  第16回日本がん転移学会
- Place of Presentation
  富山国際会議場
- Year and Date
  2007-07-10
- Data Source
  KAKENHI-PROJECT-19590900
[Presentation] Circumvention of molecular targeted drug-resistance in lung cancer.
- Author(s)
  矢野聖二
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Novel acquired resistance of molecular-targeted therapy for lung cancer.
- Author(s)
  Yano S.
- Organizer
  American Thoracic Society 2013. (Meet the Professor)
- Place of Presentation
  Pennsylvania Convention Center,USA
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Circumvention of molecular targeted drug-resistance in lung cancer.
- Author(s)
  矢野聖二
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Resistance to EGFR TKIs.
- Author(s)
  Yano S.
- Organizer
  IASLC 15th World Conference on Lung Cancer
- Place of Presentation
  Sydney Exhibition & Convention Centre, Australia
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Mechanisms of EGFR-TKI resistance and therapeutic strategies in lung cancer.
- Author(s)
  矢野聖二
- Organizer
  第54回日本肺癌学会総会
- Place of Presentation
  ホテルニューオータニ
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] 分子標的薬剤の耐性機序及びその耐性克服を目指した臨床戦略.
- Author(s)
  矢野聖二
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  ホテル　ブエナビスタ
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Resistance to EGFR TKIs.
- Author(s)
  Yano S.
- Organizer
  IASLC 15th World Conference on Lung Cancer
- Place of Presentation
  Sydney Exhibition & Convention Centre, Australia
- Data Source
  KAKENHI-PLANNED-22112010
[Presentation] Mechanisms of EGFR-TKI resistance and therapeutic strategies.
- Author(s)
  矢野聖二
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Mechanisms of EGFR-TKI resistance and therapeutic strategies in lung cancer.
- Author(s)
  矢野聖二
- Organizer
  第54回日本肺癌学会総会
- Place of Presentation
  ホテルニューオータニ
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] 分子標的薬剤の耐性機序及びその耐性克服を目指した臨床戦略.
- Author(s)
  矢野聖二
- Organizer
  第22回日本がん転移学会学術集会・総会
- Place of Presentation
  ホテル　ブエナビスタ
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Novel acquired resistance of molecular-targeted therapy for lung cancer.
- Author(s)
  Yano S.
- Organizer
  American Thoracic Society 2013. (Meet the Professor)
- Place of Presentation
  Pennsylvania Convention Center, USA
- Data Source
  KAKENHI-PROJECT-24390209
[Presentation] Mechanisms of EGFR-TKI resistance and therapeutic strategies.
- Author(s)
  矢野聖二
- Organizer
  第11回日本臨床腫瘍学会学術集会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PLANNED-22112010

1. NISHIOKA Yasuhiko (70274199)

# of Collaborated Projects: 4 results

# of Collaborated Products: 15 results
2. SONE Saburo (40145024)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
3. YASUMOTO Kazuo (90262592)

# of Collaborated Projects: 3 results

# of Collaborated Products: 18 results
4. TAKEUCHI Shinji (90565384)

# of Collaborated Projects: 2 results

# of Collaborated Products: 30 results
5. HANIBUCHI Masaki (80335794)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
6. EBI Hiromichi (00645145)

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# of Collaborated Products: 6 results
7. KAKIUCHI Soji (50380100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
8. GOTO Hisatsugu (00437641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
9. MINAMOTO Toshinari (50239323)

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# of Collaborated Products: 0 results
10. WANG Wei (80467117)

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11. YAMADA Tadaaki (00507048)

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18. MINAMI Takashi (00345141)

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19. HEISSIG Beate (30372931)

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20. TABATA Yasuhiko (50211371)

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21. ABURATANI Hiroyuki (10202657)

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22. MANO Hiroyuki (90240704)

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23. NAKA Kazuhito (70372688)

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24. HARA Eiji (80263268)

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25. SUZUKI Takeshi (30262075)

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# of Collaborated Products: 3 results
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# of Collaborated Products: 3 results
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# of Collaborated Products: 1 results
28. TANI Kenji (70207166)

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29. MUGURUMA Hiroaki (30346598)

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30. Fukuda Koji (10722548)

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# of Collaborated Products: 3 results
31. TAMURA MASAYA (10397185)

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32. 山本昭彦 (10332818)

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33. 篠原勉 (70284289)

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34. 齋藤政樹 (60012762)

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35. 梅津哉 (50251799)

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36. 土田正則 (60293221)

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37. 竹村博文 (20242521)

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38. 高田宗尚 (20459514)

# of Collaborated Projects: 1 results

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39. 喜多英治 (80134203)

# of Collaborated Projects: 1 results

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40. 松本勲 (80361989)

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42. SAKAI Katsuya

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43. RYOUHEI Katayama

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44. NISHIO makoto

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# of Collaborated Products: 1 results
45. YANAGITANI noriko

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46. TAKEUCHI kengo

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# of Collaborated Products: 1 results
47. AKIHIKO Ishimura

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48. CHIKUMI Hiroki

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49. HANAYAMA Rikinari

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50. YOSHIZAWA Hirohisa

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# of Collaborated Products: 1 results
51. TAKAHASHI Hiro

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# of Collaborated Products: 1 results
52. 佐々木素子

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53. 冨田秀太

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# of Collaborated Products: 1 results
54. 松本邦夫

# of Collaborated Projects: 0 results

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55. 中村隆弘

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# of Collaborated Products: 5 results
56. 北賢二

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# of Collaborated Products: 3 results
57. 中田光俊

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58. 田中文啓

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59. 浦本秀隆

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# of Collaborated Products: 3 results
60. 大谷咲子

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# of Collaborated Products: 1 results
61. 菊地利明

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62. 阿部貴志

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# of Collaborated Products: 2 results
63. 小郷尚久

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64. 矢守隆夫

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65. 金山博臣

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66. 高橋正幸

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# of Collaborated Products: 1 results
67. 村上孝

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# of Collaborated Products: 2 results
68. 谷本梓

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# of Collaborated Products: 1 results
69. 西山明宏

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70. 川田学

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# of Collaborated Products: 1 results
71. 清水英治

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# of Collaborated Products: 1 results
72. 寺島農

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73. 鈴木穣

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74. 山田拓司

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75. 安藤昌彦

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76. 関戸好孝

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77. 元雄良治

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# of Collaborated Products: 1 results
78. 平田英周

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# of Collaborated Products: 1 results
79. 平修

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# of Collaborated Products: 1 results
80. 高山浩一

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# of Collaborated Products: 1 results
81. 義江修

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# of Collaborated Products: 1 results

yano seiji 矢野 聖二

YANO Seiji 矢野 聖二

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Formation of a non-clinical research base for treatment aimed to eradicate lung cancer by targeted drugsPrincipal Investigator

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Study to circumvent targeted drug resistance in leptomeningeal carcinomatosis of lung cancerPrincipal Investigator

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Study to overcome metastasis and targeted drug-resistance of lung cancerPrincipal Investigator

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Development of novel therapy targeting microenvironment in respiratory malignancyPrincipal Investigator

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Development of individual therapy for overcoming HGF-induced molecular targeted drug-resistance in EGFR-mutant lung cancerPrincipal Investigator

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Identification of real target of VEGF receptor inhibitor which shows dramatic cytotoxic effect against pleural mesotheliomaPrincipal Investigator

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yano seiji 矢野聖二

YANO Seiji 矢野聖二