Ueno Megumi 上野恵美

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UENO MEGUMI 上野恵美

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Researcher Number	30296826
Affiliation (Current)	2025: 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所放射線規制科学研究部, 研究員
Affiliation (based on the past Project Information) *help	2021 – 2023: 国立研究開発法人量子科学技術研究開発機構, 放射線医学研究所放射線規制科学研究部, 研究員 2018 – 2020: 国立研究開発法人量子科学技術研究開発機構, 放射線医学総合研究所放射線障害治療研究部, 研究員(任常)
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator MRレドックスイメージング / 酸素化量 / 組織レドックスバランス / 酸素消費 / 酸素化 / TOLD MRI / 組織内レドックス状態 / レドックスイメージング / 放射線性腸炎モデル / 活性酸素種・フリーラジカル種 … More / 放射線の生物影響 / 量子生命科学 / 定量測定 / 局所反応 / 生成密度 / 初期化学反応 / 酸化反応 / 脂質ラジカル / 脂質過酸化 / 過酸化水路 / 過酸化水素 / ヒドロキシルラジカル / フリーラジカル / 活性酸素 / 生物影響 / 炭素線 / 重粒子線 / 放射線 Less

放射線性腸炎モデルの作製および放射線組織障害の進行過程の物理化学的計測Principal Investigator
- Principal Investigator
  
  上野恵美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology
Quantitative analysis of quantum beam induced initial/primary chemical reactions relating to biological molecular damagePrincipal Investigator
- Principal Investigator
  
  UENO MEGUMI
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  National Institutes for Quantum Science and Technology

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Effects of selenium deficiency on biological results of X-ray and carbon-ion beam irradiation in mice2023
- Author(s)
  Ueno Megumi、Shibata Sayaka、Nakanishi Ikuo、Aoki Ichio、Yamada Ken-ichi、Matsumoto Ken-ichiro
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 72 Issue: 2 Pages: 107-116
- DOI
  10.3164/jcbn.22-57
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07634, KAKENHI-PROJECT-22K07759, KAKENHI-PUBLICLY-22H05572, KAKENHI-PROJECT-20H00493, KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-23H05481
[Journal Article] Effects of X-ray irradiation on the redox status of mouse colorectal tissues2023
- Author(s)
  Ueno Megumi, Parajuli Raj Kumar, Ito Hiromu, Iiyama Megumi, Suzuki Saaya, Matsumoto Ken-ichiro, Nakanishi Ikuo, Aoki Ichio、Sumiyoshi Akira
- Journal Title
  
  Advances in Redox Research
  
  Volume: 8 Pages: 100067-100067
- DOI
  10.1016/j.arres.2023.100067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07759, KAKENHI-PROJECT-18K06620
[Journal Article] Simplifying quantitative measurement of free radical species using an X-band EPR spectrometer2022
- Author(s)
  Makino Yusuke、Ueno Megumi、Shoji Yoshimi、Nyui Minako、Nakanishi Ikuo、Fukui Koji、Matsumoto Ken-ichiro
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 70 Issue: 3 Pages: 213-221
- DOI
  10.3164/jcbn.21-83
- NAID
  130008134392
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07739, KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-21K07634
[Journal Article] Estimation of the Local Concentration of the Markedly Dense Hydroxyl Radical Generation Induced by X-rays in Water2022
- Author(s)
  Matsumoto Ken-ichiro、Ueno Megumi、Shoji Yoshimi、Nakanishi Ikuo
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 3 Pages: 592-592
- DOI
  10.3390/molecules27030592
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739, KAKENHI-PROJECT-18K06620
[Journal Article] Effects of LET on oxygen-dependent and-independent generation of hydrogen peroxide in water irradiated by carbon-ion beams2021
- Author(s)
  Matsumoto Ken-ichiro、Ueno Megumi、Nyui Minako、Shoji Yoshimi、Nakanishi Ikuo
- Journal Title
  
  Free Radical Research
  
  Volume: 55 Issue: 6 Pages: 589-594
- DOI
  10.1080/10715762.2021.1915489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739, KAKENHI-PROJECT-18K06620
[Journal Article] Preparation of an experimental mouse model lacking selenium-dependent glutathione peroxidase activities by feeding a selenium-deficient diet2021
- Author(s)
  上野　恵美，下川　卓志，関根(鈴木)　絵美子，乳井　美奈子，中西　郁夫，松本　謙一郎
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 68 Issue: 2 Pages: 123-130
- DOI
  10.3164/jcbn.20-36
- NAID
  130007993432
- ISSN
  0912-0009, 1880-5086
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739, KAKENHI-PROJECT-17K18375
[Journal Article] Heavy-Ion Beam-Induced Reactive Oxygen Species and Redox Reactions2021
- Author(s)
  松本　謙一郎，上野　恵美，荘司　好美，中西　郁夫
- Journal Title
  
  Free Radical Research
  
  Volume: 55 Issue: 4 Pages: 1-11
- DOI
  10.1080/10715762.2021.1899171
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739
[Journal Article] 水の放射線分解で生成する活性酸素種の定量測定と生成密度の評価2020
- Author(s)
  松本謙一郎、上野恵美、荘司好美、中西郁夫
- Journal Title
  
  放射線生物研究
  
  Volume: 55 Pages: 303-321
- NAID
  40022471866
- Data Source
  KAKENHI-PROJECT-18K07739
[Journal Article] Generation of Localized Highly Concentrated Hydrogen Peroxide Clusters in Water by X-Rays2020
- Author(s)
  上野　恵美，中西　郁夫，松本　謙一郎
- Journal Title
  
  Free Radical Research
  
  Volume: 54 Issue: 5 Pages: 360-372
- DOI
  10.1080/10715762.2020.1774574
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739
[Journal Article] Inhomogeneous Generation of Hydroxyl Radicals in Hydrogen Peroxide Solution Induced by Ultraviolet Irradiation and in a Fenton Reaction System2020
- Author(s)
  上野　恵美，中西　郁夫，松本　謙一郎
- Journal Title
  
  Free Radical Research
  
  Volume: 54 Issue: 4 Pages: 1-9
- DOI
  10.1080/10715762.2020.1819995
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06620, KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739
[Journal Article] A quantitative analysis of carbon-ion beam-induced reactive oxygen species and redox reactions2019
- Author(s)
  Matsumoto Ken-ichiro、Nyui Minako、Ueno Megumi、Ogawa Yukihiro、Nakanishi Ikuo
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 65 Issue: 1 Pages: 1-7
- DOI
  10.3164/jcbn.18-34
- NAID
  130007672105
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07695, KAKENHI-PROJECT-18K07739
[Journal Article] Reduction of molecular oxygen by redox active thiols: comparison of glutathione, N acetylcysteine, cysteine, and homocysteine2019
- Author(s)
  Minako Nyui, Yoshimi Shoji, Megumi Ueno, Ikuo Nakanishi and Ken-ichiro Matsumoto
- Journal Title
  
  J. Clin. Biochem. Nutr.
  
  Volume: 65 Pages: 185-192
- NAID
  130007740775
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] 磁気共鳴レドックスイメージングによる直腸・結腸組織内レドックス代謝活性の評価およびX線分割照射による組織内レドックス代謝活性への影響2023
- Author(s)
  上野　恵美, パラジュリ　ラジュ　クマル, 佐野　ひろみ, 伊藤　紘, 中西　郁夫, 小畠　隆行, 青木　伊知男, 松本　謙一郎, 住吉　晃
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] X線を照射した水中に生成するヒドロキシルラジカルおよび水素ラジカルの局所生成濃度とそれらの生成に対する溶存酸素の影響2023
- Author(s)
  松本　謙一郎, 牧野　祐典, 上野　恵美, 荘司　好美, 伊藤　紘, 中西　郁夫, 福井　浩二
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] An Approach for Estimating Oxygen Consumption in Tissues Based on TOLD MRI Signal2023
- Author(s)
  Ken-ichiro Matsumoto, Raj Kumar Parajuli, Hiromi Sano, Megumi Ueno, Akira Sumiyoshi, Kensuke Osada, Takayuki Obata, Ichio Aoki
- Organizer
  SfRBM-SFRRI 2023
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] Study of Oxidative Stress due to X-ray Irradiation in Mouse Brain using TOLD MRI Imaging2023
- Author(s)
  Raj Parajuli, Ueno Megumi, Suzuki Saaya, Sumiyoshi Akira, Obata Takayuki, Aoki Ichio, Matsumoto Kenichiro
- Organizer
  ISMRM2023
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] TOLD MRI信号の経時変化に基づくX線照射したマウス脳での酸素消費の評価法の開発2023
- Author(s)
  松本　謙一郎, パラジュリ　ラジュ　クマル, 上野　恵美, 鈴木　沙彩, 佐野　ひろみ, 住吉　晃, 長田　健介, 小畠　隆行, 青木　伊知男
- Organizer
  第51回日本磁気共鳴医学会大会
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] Evaluation of redox responses of mouse colorectum tissue after X-ray irradiation2022
- Author(s)
  Megumi Ueno, Raj Kumar Parajuli, Hiromu Ito, Megumi Iiyama, Saaya Suzuki, Ken-ichiro Matsumoto, Ikuo Nakanishi, Ichio Aoki, Akira Sumiyosh
- Organizer
  The Society for Redox Biology and Medicine's 29th Annual Conference (SfRBM 2022)
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] X線単回照射後のマウス直腸～結腸の組織レドックス状態の変化2022
- Author(s)
  上野　恵美、パラジュリラジュクマル、飯山　恵、鈴木　沙彩、柴田　さやか、伊藤　紘、中西　郁夫、松本　謙一郎、青木　伊知男、住吉　晃
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-22K07759
[Presentation] Generation of hydrogen peroxide in water irradiated by carbon-ion beam; Effects of dissolved oxygen and LET2021
- Author(s)
  Ueno Megumi、Minako Nyui、Nakanishi Ikuo、Matsumoto Ken-ichiro
- Organizer
  20th Biennial Meeting of SFRR International (SFRR-I 2021)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] Free Radical Generations and Reactions in an Aqueous Sample Irradiated by X-ray or 290 MeV Carbon-Ion Beam. Oxygen Radicals2020
- Author(s)
  Ken-ichiro Matsumoto, Megumi Ueno, Minako Nyui, Yoshimi Shoji, Ikuo Nakani.
- Organizer
  Oxygen Radicals, Gordon Research Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] 炭素線による水中における酸素非依存的な過酸化水素の生成2020
- Author(s)
  松本謙一郎、上野恵美、中西郁夫
- Organizer
  第73回日本酸化ストレス学会／第20回日本NO学会合同学術集会
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] Oxygen independent generation of hydrogen peroxide in water irradiated by carbon-ion beam2020
- Author(s)
  Ueno Megumi、Minako Nyui、Nakanishi Ikuo、Matsumoto Ken-ichiro
- Organizer
  27th Annual Conference of the Society for Redox Biology & Medicine (SfRBM 2020)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] 放射線を照射した際に見られるニトロキシルラジカルの減衰に対する高濃度過酸化水素の関与2019
- Author(s)
  上野恵美、松本謙一郎、中西郁夫
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] Presence of X-ray induced high concentrated hydrogen peroxide clusters2019
- Author(s)
  Megumi Ueno, Ikuo Nakanishi, Ken-ichiro Matsumoto
- Organizer
  SfRBM 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] Radiation induced generation of localized highly concentrated hydrogen peroxide in water2019
- Author(s)
  上野　恵美, 中西　郁夫, 松本　謙一郎
- Organizer
  日本放射線影響学会第62回大会
- Data Source
  KAKENHI-PROJECT-18K07739
[Presentation] 重粒子線により水中に生成する活性酸素量のLET依存性2018
- Author(s)
  松本　謙一郎、乳井　美奈子、上野　恵美、小川　幸大、中西　郁夫
- Organizer
  2018日本放射化学会年会・第62回放射化学討論会
- Data Source
  KAKENHI-PROJECT-18K07739

1. 住吉晃 (80612530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 松本謙一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 中西郁夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Ueno Megumi 上野 恵美

UENO MEGUMI 上野 恵美

Research Projects

Research Products

Co-Researchers

放射線性腸炎モデルの作製および放射線組織障害の進行過程の物理化学的計測Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Quantitative analysis of quantum beam induced initial/primary chemical reactions relating to biological molecular damagePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Effects of selenium deficiency on biological results of X-ray and carbon-ion beam irradiation in mice2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Effects of X-ray irradiation on the redox status of mouse colorectal tissues2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simplifying quantitative measurement of free radical species using an X-band EPR spectrometer2022

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Estimation of the Local Concentration of the Markedly Dense Hydroxyl Radical Generation Induced by X-rays in Water2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of LET on oxygen-dependent and-independent generation of hydrogen peroxide in water irradiated by carbon-ion beams2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preparation of an experimental mouse model lacking selenium-dependent glutathione peroxidase activities by feeding a selenium-deficient diet2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Heavy-Ion Beam-Induced Reactive Oxygen Species and Redox Reactions2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 水の放射線分解で生成する活性酸素種の定量測定と生成密度の評価2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Generation of Localized Highly Concentrated Hydrogen Peroxide Clusters in Water by X-Rays2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhomogeneous Generation of Hydroxyl Radicals in Hydrogen Peroxide Solution Induced by Ultraviolet Irradiation and in a Fenton Reaction System2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A quantitative analysis of carbon-ion beam-induced reactive oxygen species and redox reactions2019

Author(s)

Journal Title

DOI

Ueno Megumi 上野恵美

UENO MEGUMI 上野恵美