Tosa Mamiko 土佐眞美子

… Alternative Names

土佐眞美子トサマミコ

TOSA Mamiko 土佐眞美子

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Researcher Number	30301568
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2023: 日本医科大学, 医学部, 教授 2021: 日本医科大学, 医学部, 教授 2018 – 2020: 日本医科大学, 医学部, 准教授 2017: 日本医科大学, 医学部, 助手 2012 – 2016: 日本医科大学, 医学部, 講師 … More 2014: 日本医科大学, 医学部, 助教 2007 – 2011: Nippon Medical School, 医学部, 助教 1999 – 2006: 日本医科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Plastic surgery / Basic Section 56070:Plastic and reconstructive surgery-related / Plastic surgery Except Principal Investigator Plastic surgery / Plastic surgery
Keywords	Principal Investigator ケロイド / 遺伝子解析 / 組織幹細胞 / 幹細胞 / 線維芽細胞 / β-catenin / 培養線維芽細胞 / 培養細胞 / IL-6 / 空間的トランスクリプトーム解析 … More / PRMT5 / 遺伝子発現 / 治療薬 / ケロイド体質 / axin / Wnt signal / fibloblasts / keloid / β-caternin / Axin / Wntシグナル / 一塩基多型 / 遺伝子 / SNP / ＳＮＰ / ＩＬ－６ / Th17 / ケロイドモデル / IL-23 / IL-17 / IL-6受容体 / STAT3 / IL-6シグナル / 分子標的治療 / 創傷治癒学 / 移植 / 血行再開 / 走査電子顕微鏡 / 樹脂鋳型標本 / 血管新生 / 真皮下血管網皮弁 … More Except Principal Investigator ケロイド / keloid / 線維芽細胞 / 分子標的治療 / gene expression / fibroblasts / cDNA microarray / 繊維芽細胞 / 遺伝子発現 / cDNAマイクロアレイ / ＩＬ－１７ / Ｔｒｅｇ / Treg / Th17 / 制御性T細胞 / IL-17 / frizzled4 / ROR2 / frizzeld4 / wound healing / keloid pathogenesis / β-catenin / Wnt signaling / Wnt signal-related genes / EMT / beta-catenin / Wnt5a / Keloid pathogenesis / micrpRNA / コラーゲン / IL-6 / 線維化 / microRNA / 新しい分子治療 / c-Ab1 / 皮膚線維芽細胞 / 皮膚 / c-Abl Less

空間的な遺伝子解析によるケロイド発生機序の解明と新規治療標的の導出Principal Investigator
- Principal Investigator
  
  土佐眞美子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Nippon Medical School
PRMT5による新たなケロイド幹細胞制御機構の解明と新治療薬開発への挑戦Principal Investigator
- Principal Investigator
  
  土佐眞美子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56070:Plastic and reconstructive surgery-related
- Research Institution
  Nippon Medical School
Elucidation of maintenance mechanism of mesenchymal stem cells in keloid to develop new therapyPrincipal Investigator
- Principal Investigator
  
  Tosa Mamiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Elucidation of immune response by Th17/Treg in keloid and application of new therapy
- Principal Investigator
  
  MURAKAMI MASAHIRO
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Elucidation of Wnt5a signal transduction mechanism(s) in keloid and application of molecular targeted therapy
- Principal Investigator
  
  GHAZIZADEH MOHAMMAD
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
A polymorphysm in the IL-6 promotor region associated with the keloid in the Japanease populationPrincipal Investigator
- Principal Investigator
  
  MAMIKO Tosa
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
The mechanisms of transcriptional regulation by microRMAs in relation to COLIA2 promotor region in keloid
- Principal Investigator
  
  SHIMIZU Hajime
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Establishment of new molecular therapy of keloid and elucidation of mechanism of development by inhibition of cAbl tyrosine kinase
- Principal Investigator
  
  GHAZIZADEH M. (GHAZIZADEH MOHAMMAD Ghazizadeh)
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Establishment of new molecular therapy of keloid and elucidation of mechanism of development by IL-23/IL-17 pathwayPrincipal Investigator
- Principal Investigator
  
  TOSA Mamiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Establishment of novel molecular target therapy and determination of developmental mechanism of keloid by inhibition of IL-6 signalingPrincipal Investigator
- Principal Investigator
  
  TOSA Mamiko
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Molecular biological analysis of the Wnt signal pathway in keloid developmentPrincipal Investigator
- Principal Investigator
  
  TOSA Mamiko
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
Identification of genes associated with keloid development
- Principal Investigator
  
  GHAZIZADEH Mohammad
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School
新しい樹脂鋳型標本を用いた真皮下血管網皮弁における3次元的血管新生の研究Principal Investigator
- Principal Investigator
  
  土佐眞美子
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Plastic surgery
- Research Institution
  Nippon Medical School

All 2020 2019 2018 2017 2013 2012 2011 2010 2009 2008 2007 2006 2005 Other

All Journal Article Presentation

[Journal Article] ケロイドの病態と治療2020
- Author(s)
  土佐眞美子、小川　令
- Journal Title
  
  日本医科大学医学雑誌
  
  Volume: 16 Pages: 8-17
- NAID
  130007807606
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K11557
[Journal Article] Identification and characterization of Wnt signaling pathway in keloid pathogenesis2013
- Author(s)
  Shinichi Igota,Mamiko Tosa,Masahiro Murakami,Seiko Egawa,Hajime Shimizu, Hiko Hyakusoku,Mohammad Ghazizadeh
- Journal Title
  
  Int J Med Sci
  
  Volume: 10(4) Pages: 344-354
- Data Source
  KAKENHI-PROJECT-22592003
[Journal Article] Identification and characterization of Wnt signaling pathway in keloid pathogenesis2013
- Author(s)
  Shinichi Igota, Mamiko Tosa, Masahiro Murakami, Seiko Egawa, Hajime Shimizu, Hiko Hyakusoku, Mohammad Ghazizadeh
- Journal Title
  
  International Journal of Medical Sciences
  
  Volume: 10 Issue: 4 Pages: 344-354
- DOI
  10.7150/ijms.5349
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592722
[Journal Article] Clinical improvement in psoriasis with treatment of associated hyperlipidemia2011
- Author(s)
  Ghazizadeh R, Tosa M, Ghazizadeh M.
- Journal Title
  
  Am J Med Sci
  
  Volume: 341(5) Issue: 5 Pages: 394-398
- DOI
  10.1097/maj.0b013e3181ff8eeb
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592297
[Journal Article] Pathogenic Mechanisms Shared between Psoriasis and Cardiovascular Disease2010
- Author(s)
  Ghazizadeh R, Shimizu H, Tosa M, Ghazizadeh M.
- Journal Title
  
  Int J Med Sci
  
  Volume: 7(5) Pages: 284-289
- DOI
  10.7150/ijms.7.284
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592297
[Journal Article] Pathogenic Mechanisms shared between Psoriasis and cardiovascular disease2010
- Author(s)
  Ghazizadeh R,Shimizu H,Tosa M, Ghazizadeh M
- Journal Title
  
  Int J Med Sci
  
  Volume: 19;7(5) Pages: 284-289
- Data Source
  KAKENHI-PROJECT-22592003
[Journal Article] Chronologic change of the maximum dimension of BCG-induced keloids2009
- Author(s)
  Tosa M, Murakami M, Ghazizadeh M, Hyakusoku H.
- Journal Title
  
  Dermatol Surg
  
  Volume: 35(2) Issue: 2 Pages: 189-194
- DOI
  10.1111/j.1524-4725.2008.34408.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592297
[Journal Article] Functional Implications of The IL-6 Signaling Pathway in Keloid Pathogenesis2007
- Author(s)
  M Ghazizadeh. M Tosa
- Journal Title
  
  Journal of Investigative Dermatology 127
  
  Pages: 98-105
- Data Source
  KAKENHI-PROJECT-18591973
[Journal Article] Functional implications of IL-6 signaling pathway in keloid pathogenesis2007
- Author(s)
  Mohammad Ghazizadeh, Mamiko Tosa, Hajime Shimizu, Hiko Hyakusoku, Oichi Kawanami
- Journal Title
  
  J Invest Dermatol 127
  
  Pages: 98-105
- Data Source
  KAKENHI-PROJECT-18591973
[Journal Article] ケロイド発生におけるIL-6シグナル伝達経路の解析2007
- Author(s)
  土佐眞美子
- Journal Title
  
  瘢痕・ケロイド治療ジャーナル 1
  
  Pages: 56-59
- Data Source
  KAKENHI-PROJECT-18591973
[Journal Article] Global gene expression analysis of keloid fibroblasts in response to electron beam irradiation reveals the involvement of interleukin-6 pathway2005
- Author(s)
  Mamiko Tosa
- Journal Title
  
  Journal of Investigative Dermatology 124
  
  Pages: 704-713
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591906
[Journal Article] Global Gene Expression Analysis of Keloid Fibroblasts in Response to Electron Beam Irradiation Reveals the Involvement of Interleukin-6 Pathway2005
- Author(s)
  Mamiko Tosa
- Journal Title
  
  J Invest Dermatol 124
  
  Pages: 704-713
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591906
[Journal Article] Global Gene Expression Analysis of Keloid Fibroblasts in Response to Electron Beam Irradiation Reveals the Involvement of Interleukin-6 Pathway2005
- Author(s)
  Mamiko Tosa
- Journal Title
  
  Journal of Investigative Dermatology 124
  
  Pages: 704-713
- Data Source
  KAKENHI-PROJECT-15591906
[Journal Article] Global Gene Expression Analysis of Keloid Fibroblasts in Response to Electron Beam irradiation Reveals the Involvement of Interleukin-6 Pathway2005
- Author(s)
  Tosa M
- Journal Title
  
  Journal of Investigative Dermatology 124
  
  Pages: 704-713
- Data Source
  KAKENHI-PROJECT-15591906
[Presentation] Hedgehog Signaling Pathway Maintains Mesenchymal Stem Cells in Keloid.2020
- Author(s)
  Mamiko Tosa, Y Abe, R Ogawa, N Tanaka
- Organizer
  The Meeting American Society of Plastic Surgery. 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] Hedgehog Signaling Pathway Maintains Mesenchymal Stem Cells in Keloid.2020
- Author(s)
  Mamiko Tosa, Y Abe, R Ogawa, N Tanaka
- Organizer
  The Meeting American Society of Plastic Surgery. 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09855
[Presentation] ケロイド真皮由来間葉系幹細胞に着目したケロイド発症機構の解明と治療への応用2019
- Author(s)
  土佐眞美子、阿部芳憲、田中信之、小川　令
- Organizer
  第27回日本形成外科基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] ケロイド新治療薬開発に向けたケロイド患者と健常人の真皮における遺伝子発現プロファイル解析2018
- Author(s)
  土佐眞美子、阿部芳憲、田中信之、小川　令
- Organizer
  第10回日本創傷外科学会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] ケロイド新治療薬開発への挑戦2018
- Author(s)
  土佐眞美子、阿部芳憲、田中信之、小川　令
- Organizer
  第27回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] ケロイド病変部位における遺伝子発現プロファイルの検討2017
- Author(s)
  土佐眞美子
- Organizer
  第26回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-17K11557
[Presentation] ケロイド患者におけるIL-6関連遺伝子多型パターンと臨床像との関連について2013
- Author(s)
  土佐眞美子、渡邉　淳、村上正洋、ガジザデ・モハマッド
- Organizer
  第56回日本形成外科学会総会
- Place of Presentation
  京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24592723
[Presentation] ケロイド患者におけるIL_6 関連遺伝子多型パターンと臨床像との関連について2013
- Author(s)
  土佐眞美子、村上正洋、枝川聖子、ガジザデ・モハマッド
- Organizer
  第56回日本形成外科学会総会・学術集会
- Place of Presentation
  新宿京王プラザホテル
- Data Source
  KAKENHI-PROJECT-24592723
[Presentation] MicroRNA expression profiles in keloid and normal dermal fibroblasts2012
- Author(s)
  Hajime Shimizu,Shinichi Igota,MamikoTosa,Seiko Egawa,Mohammad Ghazizadeh
- Organizer
  第37回日本研究皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] Involvement of a Wnt/ss-catenin canonical signaling pathway in keloid pathogenesis2012
- Author(s)
  Mohammad Ghazizadeh,Seiko Egawa, Hajime Shimizu,Shinichi Igota,Mamiko Tosa
- Organizer
  第37回日本研究皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] Potential involvement of the stem cell factor (SCF) receptor c-kit in keloid pathogenesis2012
- Author(s)
  Mohammad Ghazizadeh, Seiko Egawa, Hajime Shimizu, Shinichi Igota, Mamiko Tosa
- Organizer
  第１１１回日本皮膚科学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24592722
[Presentation] Potential involvement of the stem cell factor receptor c-kit in keloid Pathogenesis2012
- Author(s)
  Mohammad Ghazizadeh, Hajime Shimizu, Seiko Egawa, Mamiko Tosa
- Organizer
  第111回日本皮膚科学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] Characterization of Wnt signaling pathway in keloid pathogenesis.2012
- Author(s)
  Mohammad Ghazizadeh,Seiko Egawa, Hajime Shimizu,Shinichi Igota, Mamiko Tosa
- Organizer
  65 th International Conference on Tissue Science and Engineering
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] Involvement of a Wnt/beta-catenin canonical signaling pathway in keloid pathogenesis2012
- Author(s)
  Mohammad Ghazizadeh, Seiko Egawa, Hajime Shimizu, Shinichi Igota, Mamiko Tosa
- Organizer
  日本研究皮膚科学会第３７回年次学術大会総会
- Place of Presentation
  那覇
- Data Source
  KAKENHI-PROJECT-24592722
[Presentation] Potential involvement of the stem cell factor receptor c-kit in keloid pathogenesis2012
- Author(s)
  Mohammad Ghazizadeh,Hajime Shimizu, Seiko Egawa,Mamiko Tosa
- Organizer
  第110回日本皮膚科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] 顔面の組織欠損に対する再建方法の検討2011
- Author(s)
  伊吾田慎一、ガジザデモハマッド、土佐眞美子、清水一、枝川聖子、岩切致、村上正洋、小川令、百束比古
- Organizer
  第3回日本創傷外科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] ケロイド発症の病因に関与するmicroRNA遺伝子について2011
- Author(s)
  清水一、土佐眞美子、ガジザデモハマッド
- Organizer
  第25回日本皮膚外科学会総会
- Place of Presentation
  富山
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] Involvement of Wnt signaling pathway in abnormal wound healing2011
- Author(s)
  Mohammad Ghazizadeh,Hajime Shimizu, Shinichi Igota,Seiko Egawa,Mamiko Tosa
- Organizer
  第3回日本創傷外科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] ケロイドにおけるTh17細胞のIL-6シグナル促進効果の検討2011
- Author(s)
  土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
- Organizer
  第20回日本形成外科基礎学術集会
- Place of Presentation
  新宿
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] Characterization of Wnt signaling pathway in keloidpathogenesis2011
- Author(s)
  Tomoyo Ueno,Shinichi Igota,Mamiko Tosa,Seiko Egawa,Hajime Shimizu, Mohammad Ghazizadeh
- Organizer
  第79回日本医科大学医学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] Targeting the Wnt signaling pathwain keloid2011
- Author(s)
  Mohammad Ghazizadeh, Shinichi Igota, Hajime Shimizu, Seiko Egawa, Mamiko Tosa
- Organizer
  第26回日本皮膚外科学会総会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] Involvement of Wnt signaling pathway in keloid pathogenesis2011
- Author(s)
  伊吾田慎一、土佐眞美子、枝川聖子、清水一、村上正洋、百束比古、ガジザデモハマッド
- Organizer
  第20回日本形成外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] 炎症的側面と腫瘍的側面を持つケロイドに対する基礎的アプローチ2011
- Author(s)
  土佐眞美子
- Organizer
  第20回日本形成外科学会基礎学術集会
- Place of Presentation
  ハイアットリージェンシー東京
- Year and Date
  2011-10-06
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] Characterization of Wnt signaling pathway in keloid pathogenesis2011
- Author(s)
  Tomoyo Ueno, Mamiko Tosa, Hajime Shimizu, Mohammad Ghazizadeh
- Organizer
  第79回日本医科大学医学会総会
- Place of Presentation
  東京
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] Targeting the Wnt signaling Pathway in keloid2011
- Author(s)
  Mohammad Ghazizadeh,Shinichi Igota, Hajime Shimizu,Seiko Egawa,Mamiko Tosa
- Organizer
  第26回日本皮膚外科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] Involvement of Wnt signaling pathway in keloid pathogenesis2011
- Author(s)
  伊吾田慎一、土佐眞美子、清水一、村上正洋、ガジザデモハマッド
- Organizer
  第20回日本形成外科学会基礎学術集会
- Place of Presentation
  東京
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] Targeting the Wnt signaling pathway in keloid2011
- Author(s)
  Mohammad Ghazizadeh, Hajime Shimizu, Mamiko Tosa
- Organizer
  第26回日本皮膚外科学会総会
- Place of Presentation
  富山
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] ケロイド発症の病因に関与するmicroRNA遺伝子について2011
- Author(s)
  清水一、土佐眞美子、ガジザデモハマッド
- Organizer
  第25回日本皮膚外科学会総会
- Place of Presentation
  富山
- Year and Date
  2011-08-20
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] ケロイド発症の病因に関与するmicroRNA遺伝子について2011
- Author(s)
  清水一土佐眞美子、伊吾田慎一、枝川聖子、ガジザデモハマッド
- Organizer
  第26回日本皮膚外科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] Functional implication of the IL-6 signaing pathway in keloid pathogenesis2010
- Author(s)
  Mamiko Tosa, Mohammad Ghazizadeh
- Organizer
  International scar meeting in Tokyo
- Place of Presentation
  東京
- Year and Date
  2010-11-30
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] Inhibition of keloid fibroblast cell growth by a Src family-specific tyrosine kinase inhibitor2010
- Author(s)
  Mohammad Ghazizadeh, Hajime Shimizu、Seiko Egawa, Mamiko Tosa
- Organizer
  第25回日本皮膚外科学会総会
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] ケロイドにおけるTh17細胞のIL-6シグナル促進効果の検討2010
- Author(s)
  土佐眞美子、モハマッド・ガジザデ
- Organizer
  第19回日本形成外科学会基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] Inhibition of keloid fibroblast cell growth by a Src family-specific tyrosine kinase inhibitor2010
- Author(s)
  Mohammad Ghazizadeh,Hajime Shimizu、Seiko Egawa, Mamko Tosa
- Organizer
  第25回日本皮膚外科学会総会
- Data Source
  KAKENHI-PROJECT-22592003
[Presentation] 炎症的側面と腫瘍的側面を持つケロイドに対する基礎的アプローチ2010
- Author(s)
  土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
- Organizer
  第19回日本形成外科基礎学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] ケロイド患者におけるヘルパーT細胞サブタイプの解析2009
- Author(s)
  土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
- Organizer
  第18回日本形成外科基礎学術集会
- Place of Presentation
  東京
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] ケロイド患者におけるヘルパーT細胞の分布解析2009
- Author(s)
  土佐眞美子
- Organizer
  第18回日本形成外科学会基礎学術集会
- Place of Presentation
  東京都・都市センターホール
- Data Source
  KAKENHI-PROJECT-21592298
[Presentation] Effect of imatinib mesylate(STI571) on keloid fibroblast cell functions2009
- Author(s)
  Ghazizadeh M, Shimizu H, Tosa M, Egawa Seiko, Murakami M
- Organizer
  The 34th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-21592297
[Presentation] Autocrine IL-6 growth regulation in keloid fibroblasts2008
- Author(s)
  Mohammad Ghazizadeh, Mamiko Tosa, Hajime Shimizu, Oichi Kawanami
- Organizer
  Systems Biology of Disease Conference
- Place of Presentation
  Jun,Boston
- Data Source
  KAKENHI-PROJECT-18591973
[Presentation] ケロイドに対する新治療薬としてのヒト化抗ヒトIL-6受容体抗体の臨床応用を目指した基礎研究2007
- Author(s)
  土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
- Organizer
  第16回日本形成外科基礎学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-18591973
[Presentation] ケロイドに対する新治療薬としてのヒト抗ヒトIL-6受容体抗体の臨床応用を目指した基礎研究2007
- Author(s)
  土佐眞美子
- Organizer
  第16回日本形成外科学会基礎学術集会
- Place of Presentation
  クラウンプラザ神戸
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18591973
[Presentation] IL-6-mediated autocrine growth regulation in keloid fibroblast2007
- Author(s)
  清水一、川並汪一、土佐眞美子
- Organizer
  第59日本皮膚科学会西部支部学術大会
- Place of Presentation
  宮崎
- Data Source
  KAKENHI-PROJECT-18591973
[Presentation] 抗IL-6受容体抗体によるケロイド由来線維芽細胞の増殖抑制効果の検討2006
- Author(s)
  土佐眞美子、ガジザデ・モハマッド、村上正洋、百束比古
- Organizer
  第15回日本形成外科基礎学術集会
- Place of Presentation
  大宮
- Data Source
  KAKENHI-PROJECT-18591973
[Presentation] Activation of IL-6 signal pathway in keloid pathogenesis2006
- Author(s)
  ガジザデ・モハマッド、土佐眞美子, 他5名
- Organizer
  第70回日本皮膚科学会東部支部学術大会
- Place of Presentation
  弘前
- Data Source
  KAKENHI-PROJECT-18591973
[Presentation] IL-6 promoter polymorphisms and keloid susceptibility in the Japanese population.
- Author(s)
  M. Ghazizadeh, M. Tosa, Atsushi. Watanabe, S. Egawa, H. Murakami.
- Organizer
  第6回日本創傷治癒外科学会総会
- Place of Presentation
  高松市
- Year and Date
  2014-07-24 – 2014-07-25
- Data Source
  KAKENHI-PROJECT-24592723
[Presentation] Interleukin-6 promoter polymorphism associated with keloid in the Japanese population
- Author(s)
  M. Ghazizadeh, M. Tosa
- Organizer
  第25回日本疫学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2015-01-21 – 2015-01-25
- Data Source
  KAKENHI-PROJECT-24592723
[Presentation] Wnt/beta-catenin signaling is involved in keloid pathogenesis
- Author(s)
  M. Ghazizadeh, S. Igota, S. Egawa, M. Tosa
- Organizer
  3rd International Conference on Surgery and Anesthesia
- Place of Presentation
  Chicago、USA
- Year and Date
  2014-11-17 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-24592722
[Presentation] ケロイド患者におけるIL-6一塩基多型とIL-6値の関連についての検討
- Author(s)
  土佐眞美子、ガジザデ・モハマッド、村上正洋
- Organizer
  第23回形成外科基礎学術集会
- Place of Presentation
  松本市
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592723
[Presentation] Wnt/beta-catenin signaling in keloid pathogenesis
- Author(s)
  Mohammad Ghazizadeh, Mamiko Tosa, Seiko Egawa
- Organizer
  第23回日本形成外科学会基礎学術集会
- Place of Presentation
  松本市
- Year and Date
  2014-10-09 – 2014-10-10
- Data Source
  KAKENHI-PROJECT-24592722

1. MOHAMMAD Ghazizadeh (30190979)

# of Collaborated Projects: 8 results

# of Collaborated Products: 50 results
2. MURAKAMI Masahiro (00239500)

# of Collaborated Projects: 7 results

# of Collaborated Products: 9 results
3. SHIMIZU Hajime (60398873)

# of Collaborated Projects: 4 results

# of Collaborated Products: 26 results
4. KAWANAMI Ouichi (70096973)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
5. 阿部芳憲 (00386153)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. HIRAI Takashi (40208799)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. WATANABE Atsushi (10307952)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. MINAMI SHIROU (10192361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. EMI Mitsuro (90221118)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 金恩京 (10312068)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Tosa Mamiko 土佐 眞美子

土佐 眞美子 トサ マミコ

TOSA Mamiko 土佐 眞美子

Research Projects

Research Products

Co-Researchers

空間的な遺伝子解析によるケロイド発生機序の解明と新規治療標的の導出Principal Investigator

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PRMT5による新たなケロイド幹細胞制御機構の解明と新治療薬開発への挑戦Principal Investigator

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Elucidation of maintenance mechanism of mesenchymal stem cells in keloid to develop new therapyPrincipal Investigator

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Elucidation of immune response by Th17/Treg in keloid and application of new therapy

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Elucidation of Wnt5a signal transduction mechanism(s) in keloid and application of molecular targeted therapy

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A polymorphysm in the IL-6 promotor region associated with the keloid in the Japanease populationPrincipal Investigator

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The mechanisms of transcriptional regulation by microRMAs in relation to COLIA2 promotor region in keloid

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Establishment of new molecular therapy of keloid and elucidation of mechanism of development by inhibition of cAbl tyrosine kinase

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Establishment of new molecular therapy of keloid and elucidation of mechanism of development by IL-23/IL-17 pathwayPrincipal Investigator

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Establishment of novel molecular target therapy and determination of developmental mechanism of keloid by inhibition of IL-6 signalingPrincipal Investigator

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Molecular biological analysis of the Wnt signal pathway in keloid developmentPrincipal Investigator

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Identification of genes associated with keloid development

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新しい樹脂鋳型標本を用いた真皮下血管網皮弁における3次元的血管新生の研究Principal Investigator

Principal Investigator

Tosa Mamiko 土佐眞美子

土佐眞美子トサマミコ

TOSA Mamiko 土佐眞美子