Nakamura Tsutomu 中村勉

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NAKAMURA Tsutomu 中村勉

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Researcher Number	30302798
Other IDs
Affiliation (based on the past Project Information) *help	2021: 東京大学, 定量生命科学研究所, 客員准教授 2018 – 2019: 東京大学, 定量生命科学研究所, 客員准教授 2017: 東京大学, 分子細胞生物学研究所, 客員准教授 2009 – 2013: The University of Tokyo, 分子細胞生物学研究所, 講師 2009: 東京大学, 分子細胞生物学研究所, 助教 2007: 東京大学, 分子細胞生物学研究所, 講師 2001 – 2006: 東京大学, 分子細胞生物学研究所, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Basic Section 57020:Oral pathobiological science-related / Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Pathological medical chemistry / General medical chemistry / General medical chemistry Except Principal Investigator General medical chemistry / Biological Sciences
Keywords	Principal Investigator シグナル伝達 / Wnt / PSD / RICS / ICAT / シナプス / 脳・神経 / 神経科学 / スパイン / SPAL-1 … More / PSD-95 / Syncytin / 細胞融合 / Gcm1 / Bcl9-like / 胎盤 / 記憶 / CaMKII / β-カテニン / 発生・分化 / サイトカイン / 炎症性疾患 / マイクロバイオーム / 口腔細菌 / ディスバイオーシス / 口腔細菌叢 / アトピー性皮膚炎 / 過敏性腸症候群 / 多発性硬化症 / 乾癬 / 口腔マイクロバイオーム / 脳神経疾患 / アクチン / Cdc42 / グルタミン酸受容体 / spine / memory / learning / NMDA receptor / synapse / 学習 / NMDA受容体 / 浸潤・転移 / 組織修復・再生 / 転移 / 浸潤 / 組織再生 / 組織修復 / 絨毛癌 / 【〇!R】-catenin / TCF4 / β-catenin / 発現制御 / 脳高次機能 / 成長円錐 / 領域特異化 / 神経 / ノックアウトマウス / 分化 / 癌抑制遺伝子 / 癌遺伝子 / 肝癌 / 大腸癌 / 癌 / BAMBI / TGF-β / 神経発生 / N-カドヘリン … More Except Principal Investigator β-catenin / RICS / N-cadherin / PX-RIGS / 樹状突起 / ニューロン / 14-3-3ζ/θ / シナグル伝達 / GABARAP / 14-3-3 / CaMKII / NMDA受容体 / RICS/PX-RICS / スパイン / 脳・神経 / シグナル伝達 / 神経可塑性 / 分子神経生物学 / 細胞内情報伝達 / B9L / Sam68 / 細胞運動 / Dlg / G蛋白質 / GEF / 血管新生 / 神経突起伸長 / 癌抑制遺伝子 / カドヘリン / beta-catenin / 細胞運動・浸潤 / 細胞がん化 / Wnt / がん幹細胞 / Asef / APC / p53 / 増殖 / アポトーシス / がん遺伝子 / がん抑制遺伝子 Less

慢性炎症疾患の口腔マイクロバイオーム解析Principal Investigator
- Principal Investigator
  
  中村勉
- Project Period (FY)
  2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  The University of Tokyo
Regulation of spine morphology by RICS-dependent Cdc42 signalingPrincipal Investigator
- Principal Investigator
  
  Nakamura Tsutomu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
Roles of cell fusion in tissue regeneration and tumorigenesisPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tsutomu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo
Activity-dependent regulation of spine morphology by RICS/PX-RICS
- Principal Investigator
  
  AKIYAMA Tetsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Regulation of placenta development by Wnt signalingPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tsutomu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Molecular mechanism of tumor cell growth
- Principal Investigator
  
  AKIYAMA Tetsu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Regulation of synaptic function by NMDA receptor/PSD-95/SPAL-1 complexPrincipal Investigator
- Principal Investigator
  
  NAKAMURA Tsutomu
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
β-カテニンとそのパートナー分子ICATおよびRICSによる神経発生の制御機構Principal Investigator
- Principal Investigator
  
  中村勉
- Project Period (FY)
  2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
β-カテニンとそのパートナー分子ICATおよびRICSによる神経発生の制御機構Principal Investigator
- Principal Investigator
  
  中村勉
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
β-カテニンとそのパートナー分子による神経発生の制御機構Principal Investigator
- Principal Investigator
  
  中村勉
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Wntシグナルの抑制因子ICATを利用した新規Wnt標的遺伝子の同定Principal Investigator
- Principal Investigator
  
  中村勉
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
β-カテニンとそのパートナー分子による神経発生の制御機構Principal Investigator
- Principal Investigator
  
  中村勉
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2018 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] The autism-related protein PX-RICS mediates GABAergic synaptic plasticity in hippocampal neurons and emotional learning in mice.2018
- Author(s)
  Nakamura T, Sakaue F, Nasu-Nishimura Y, Takeda Y, Matsuura K, Akiyama T
- Journal Title
  
  EBioMedicine
  
  Volume: 34 Pages: 189-200
- DOI
  10.1016/j.ebiom.2018.07.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07104, KAKENHI-PLANNED-17H06325, KAKENHI-PROJECT-17H01537
[Journal Article] Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway2011
- Author(s)
  Matsuura K, Jigami T, Taniue K, Morishita Y, Adachi S, Senda T, Nonaka A,Aburatani H, Nakamura T, Akiyama T
- Journal Title
  
  Nat Commun
  
  Volume: 2 Issue: 1 Pages: 548-548
- DOI
  10.1038/ncomms1551
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20221009, KAKENHI-PROJECT-21390075, KAKENHI-PROJECT-21590301, KAKENHI-PLANNED-22112004
[Journal Article] Akiyama T The PX-RICS-14-3-3ζ/θcomplex couples N-cadherin-β-catenin with dynein-dynactin to mediate its export from the endoplasmic reticulum2010
- Author(s)
  Nakamura T, Hayashi T, Mimori-Kiyosue Y, Sakaue F, Matsuura K, Iemura S, Natsume T
- Journal Title
  
  J Biol Chem
  
  Volume: 285 Issue: 21 Pages: 16145-16154
- DOI
  10.1074/jbc.m109.081315
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390075
[Journal Article] Akiyama T The PX-RICS-14-3-3ζ/θcomplex couples N-cadherin-β-catenin with dynein-dynactin to mediate its export from the endoplasmic reticulum2010
- Author(s)
  Nakamura T, Hayashi T, Mimori-Kiyosue Y, Sakaue F, Matsuura K, Iemura S, Natsume T
- Journal Title
  
  J Biol Chem 285
  
  Pages: 16145-16154
- URL
  http://www.jbc.org/content/285/21/16145.long
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590301
[Journal Article] The expression of hDlg as a biomarker of the outcome in malignant fibrous histiocytomas2010
- Author(s)
  Niimi R, Matsumine A, Iino T, Murata T, Shintani K, Nakazora S, Nakamura T, Uehara Y, Kusuzaki K, Akiyama T, Uchida A
- Journal Title
  
  Oncol Rep
  
  Volume: 23 Issue: 3 Pages: 631-638
- DOI
  10.3892/or_00000678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390075
[Journal Article] The PX-RICS/14-3-3ζ/θ complex couples N-cadherin/β-catenin with dynein/dynactin to mediate its export from the endoplasmic reticulum.2010
- Author(s)
  T.Nakamura,
- Journal Title
  
  J.Biol.Chem. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390075
[Journal Article] The PX-RICS/14-3-3ζ/θ complex couples N-cadherin/b-catenin with Dynein/Dynactin to mediate its export from the endoplasmic reticulum.2010
- Author(s)
  Nakamura T.
- Journal Title
  
  J.Biol.Chem
  
  Volume: 285 Pages: 16145-16154
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390075
[Journal Article] The PX-RICS/14-3-3ζ/θ complex couples N-cadherin/β-catenin with dynein/dynactin to mediate its export from the endoplasmic reticulum2010
- Author(s)
  T.Nakamura
- Journal Title
  
  J.Biol.Chem (掲載確定, in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014011
[Journal Article] PX-RICS mediates ER-to-Golgi transport of the N-cadherin/β-catenin complex2008
- Author(s)
  Nakamura T.
- Journal Title
  
  Genes Dev. 22
  
  Pages: 1244-1256
- Data Source
  KAKENHI-PROJECT-17014011
[Journal Article] PX-RICS mediates ER-to-Golgi transport of the N-cadherin/-catenin complex.2008
- Author(s)
  Nakamura T., Hayashi T., Nasu-Nishimura Y., Sakaue F., Okabe T., Ohwada S., Matsuura K., Akiyama T.
- Journal Title
  
  Genes Dev. 22
  
  Pages: 1244-1256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014011
[Journal Article] PX-RICS mediates ER-to-Golgi transport of the N-cadherin/b-catenin complex.
- Author(s)
  Nakamura T.
- Journal Title
  
  Genes Dev (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17014011
[Journal Article] The PX-RICS/14-3-3ζ/θcomplex couples N-cadherin/ β-catenin with dynein/dynactin to mediate its export from the endoplasmic reticulum.
- Author(s)
  Nakamura T., Hayashi T., Mimori-Kiyosue Y., Sakaue F., Matsuura K., Imura S., Natsume T., T. Akiyama.
- Journal Title
  
  J. Biol. Chem. (in press)
- Data Source
  KAKENHI-PROJECT-17014011
[Presentation] Regulation of cell fusion through Wnt signaling - Novel insight into cell fusion biology2012
- Author(s)
  Ken Matsuura, Takafumi Jigami, Kenzui Taniue, Yasuyuki Morishita, Shungo Adachi, Takao Senda, Aya Nonaka, Hiroyuki Aburatani, Tsutomu Nakamura, Tetsu Akiyama
- Organizer
  EMBO Conference 30 years of Wnt signaling
- Place of Presentation
  Egmond aan Zee, Netherlands
- Data Source
  KAKENHI-PROJECT-24659146
[Presentation] Regulation of cell fusion through Wnt signaling–Novel insight into cell fusion biology2012
- Author(s)
  Ken Matsuura, Takafumi Jigami, Kenzui Taniue, Yasuyuki Morishita, Shungo Adachi, Takao Senda, Aya Nonaka, Hiroyuki Aburatani, Tsutomu Nakamura, Tetsu Akiyama
- Organizer
  EMBO Conference 30 years of Wnt signaling
- Place of Presentation
  Egmond aan Zee, Netherlands
- Data Source
  KAKENHI-PROJECT-24659146
[Presentation] Wntシグナルによる細胞融合制御メカニズムの解明～ヒト妊娠異常から組織再生2012
- Author(s)
  松浦憲,地神貴文,谷上賢瑞,森下保幸,足立俊吾,千田隆夫,野中綾,油谷浩幸,中村勉,秋山徹
- Organizer
  がん発症のメカニズムへ～.第35回日本分子生物学会年会ワークショップ(細胞内シグナル伝達システムとがん研究の新展開)
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-24659146
[Presentation] Wnt/β-cateninシグナルが細胞融合シグナルを制御する新規シグナル伝達経路の同定2010
- Author(s)
  松浦憲,地神貴史,谷上賢瑞,森下保幸,足達俊吾,千田隆夫,油谷浩幸,中村勉,秋山徹
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21590301
[Presentation] PX-RICS/14-3-3ζ/θ複合体はN-cadherin/β-catenin複合体とdynein/dynactin複合体をリンクしその小胞体輸出を制御する2010
- Author(s)
  中村勉,林寛敦,清末優子,坂上史佳,松浦憲,家村俊一郎,夏目徹,秋山徹
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21390075
[Presentation] PX-RICS/14-3-3ζ/θ複合体はN-cadherin/β-catenin複合体とdynein/dynactin複合体をリンクしその小胞体輸出を制御する2010
- Author(s)
  中村勉,林寛敦,清末優子,坂上史佳,松浦憲,家村俊一郎,夏目徹,秋山徹
- Organizer
  第62回日本細胞生物学会大会
- Place of Presentation
  大阪
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-21390075
[Presentation] Wnt/β-cateninシグナルが細胞融合シグナルを制御する新規シグナル伝達経路の同定2010
- Author(s)
  松浦憲,地神貴史,谷上賢瑞,森下保幸,足達俊吾,千田隆夫,油谷浩幸,中村勉,秋山徹
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21390075
[Presentation] PX-RICSはN-cadherin/β-catenin複合体の小胞体-ゴルジ体輸送を制御する.ミニシンポジウム(細胞間接着研究の新展開)2009
- Author(s)
  中村勉,林寛敦,那須-西村教子,坂上史佳,森下保幸,夏目徹,松浦憲,秋山徹
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-21590301
[Presentation] PX-RICSはN-cadherin/β-catenin複合体の小胞体-ゴルジ体輸送を制御する.ミニシンポジウム(細胞間接着研究の新展開)2009
- Author(s)
  中村勉,林寛敦,那須-西村教子,坂上史佳,森下保幸,夏目徹,松浦憲,秋山徹
- Organizer
  第61回日本細胞生物学会大会
- Place of Presentation
  名古屋
- Year and Date
  2009-06-03
- Data Source
  KAKENHI-PROJECT-21390075
[Presentation] Wntシグナルによる細胞融合制御メカニズムの解明～ヒト妊娠異常から組織再生、がん発症のメカニズムへ～
- Author(s)
  松浦憲、地神貴文、谷上賢瑞、森下保幸、足立俊吾、千田隆夫、野中綾、油谷浩幸、中村勉、秋山徹
- Organizer
  第35回日本分子生物学会年会ワークショップ（細胞内シグナル伝達システムとがん研究の新展開）
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24659146

1. AKIYAMA Tetsu (70150745)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. NASU Ryo (30466859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. KAWASAKI Yoshihiro (10376642)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUURA Ken (10625742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 油谷浩幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakamura Tsutomu 中村 勉

NAKAMURA Tsutomu 中村 勉

Research Projects

Research Products

Co-Researchers

慢性炎症疾患の口腔マイクロバイオーム解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of spine morphology by RICS-dependent Cdc42 signalingPrincipal Investigator

Principal Investigator

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Research Institution

Roles of cell fusion in tissue regeneration and tumorigenesisPrincipal Investigator

Principal Investigator

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Research Category

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Research Institution

Activity-dependent regulation of spine morphology by RICS/PX-RICS

Principal Investigator

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Research Institution

Regulation of placenta development by Wnt signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Molecular mechanism of tumor cell growth

Principal Investigator

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Review Section

Research Institution

Regulation of synaptic function by NMDA receptor/PSD-95/SPAL-1 complexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

β-カテニンとそのパートナー分子ICATおよびRICSによる神経発生の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

β-カテニンとそのパートナー分子ICATおよびRICSによる神経発生の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

β-カテニンとそのパートナー分子による神経発生の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Wntシグナルの抑制因子ICATを利用した新規Wnt標的遺伝子の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

β-カテニンとそのパートナー分子による神経発生の制御機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The autism-related protein PX-RICS mediates GABAergic synaptic plasticity in hippocampal neurons and emotional learning in mice.2018

Author(s)

Journal Title

Nakamura Tsutomu 中村勉

NAKAMURA Tsutomu 中村勉