MIYAZAKI Yoshiji 宮崎義司

Researcher Number	30303960
Affiliation (based on the past Project Information) *help	1999 – 2002: Osaka University Graduate School of Medicine, Assistant Professor, 医学系研究科, 助手 1998: Osaka University Medical School, Assistant Professor, 医学部, 助手
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator amphiregulin / HB-EGF / TRAF6 / NIK / protein kinase C / IKK / NF-kappaB / Ets / AP-1 / cyclin D1 … More / PPARγ / ras / STAT3 / gastric epithelial cells / gastrin / H-pylori / 胃上皮細胞 / ガストリン / H.pylori / differentiation / growth / 消化管上皮 / 分化 / 増殖 / dominant-negative / apoptosis / EGF-related peptides / EGF receptor / トランスジェニックマウス / 癌化 / 修復 / 胃粘膜 / ドミナント・ネガティブ / アポトーシス / EGF関連ペプチド / EGF受容体 … More Except Principal Investigator c-kit / 胃癌 / CD9 / HB-EGF / IL-1 / Helicobacter pylori / CD40 / IL-10 / IRF-1 / bak / bcl-xL / アポトーシス / 大腸癌 / gastritis / gastrin / gastric cancer / PKC / メチル化 / p38-MAPK / NF-κB / 胃炎 / ガストリン / lipopolysaccharide / mice / macrophage / Conh's disease / IL-12 / TNFα / エンドトキシン / マウス / マクロファージ / クローン病 / apoptosis / mutation / leiomyosarcoma / leimyoma / gastrointestinal stromal tumor / 遺伝子変異 / 平滑筋肉腫 / 平滑筋腫 / 消化管腫瘍 / pacemaker / interstitial cells of Cajal / gastrointestinal motility / カハール / 消化管運動異常症 / ペースメーカー / カハール介在細胞 / 消化管運動 / Stat3 / Missence mutation / Apoptosis / Colorectal cancer / Gastric cancer / astat3 / アポト-シス / IRF-2 / Star3 / ミスセンス変異 / EGF / HGF / 悪性黒色腫 / 転移 Less

新規癌転移関連分子Mlzeの機能解析-消化器癌の転移における役割-
- Principal Investigator
  
  SHINOMURA Yasuhisa
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Interaction of proinflammatory cytokines and growth factors in gastric carcinogenesis
- Principal Investigator
  
  SHINOMURA Yasuhisa
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Development of a new therapy of Chohn's disease by the regulation of Macrophage/Monocyte function
- Principal Investigator
  
  KIYOHARA Tatsuya
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Role of NF-kappaB in the growth, differentiation and apoptosis of gastric epithelial cellsPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Yoshiji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Effect of gain-of-function mutation of c-kit on apoptosis in gastrointestinal mesenchymal cells
- Principal Investigator
  
  SHINOMURA Yasuhisa
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Development of novel therapeutics targeting the function of intestinal cells of Cajal in gastrointestinal motility disorder
- Principal Investigator
  
  SHINOMURA Yasuhisa
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Role of PPARγ in the growth, differentiation and apoptosis of gastrointestinal epithelial cells.Principal Investigator
- Principal Investigator
  
  MIYAZAKI Yoshiji
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Research on the abnormal expressions of bcl-xL and bak in gastrointestinal cancers
- Principal Investigator
  
  KANAYAMA Shuji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University
Role of EGF receptor in the growth, differentiation and apoptosis resistance of gastrointestinal epithelial cells.Principal Investigator
- Principal Investigator
  
  MIYAZAKI Yoshiji, 東本好文
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka University

All 2005 2004 2003 2002

All Journal Article

[Journal Article] Gefitinib (‘Iressa', ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.2005
- Author(s)
  Kishida O, Miyazaki Y, Murayama Y, Ogasa M, Miyazaki T, Yamamoto T, Watabe K, Tsutsui S, Kiyohara T, Shimomura I, Shinomura Y.
- Journal Title
  
  Cancer Chemoth.Pharm. 55(4)
  
  Pages: 393-403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells.2004
- Author(s)
  Murayama Y, Miyagawa J, Oritani K, Yoshida H, Yamamoto K, Kishida O, Miyazaki T, Tsutsui S, Kiyohara T, Miyazaki Y, Higashiyama S, Matsuzawa Y, Shinomura Y
- Journal Title
  
  J Cell Sci. 117(Pt 15)
  
  Pages: 3379-3388
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Helicobacter pylori-induced enlarged-fold gastritis is associated with increased mutagenicity of gastric juice, increased oxidative DNA damage, and an increased risk of gastric carcinoma.2003
- Author(s)
  Nishibayashi H, Kanayama S, Kiyohara T, Yamamoto K, Miyazaki Y, Yasunaga Y, Shinomura Y, Takeshita T, Takeuchi T, Morimoto K, Matsuzawa Y
- Journal Title
  
  J Gastroenterol Hepatol. 18(12)
  
  Pages: 1384-1391
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Endoscopic ultrasonography-guided fine needle aspiration biopsy in follow-up patients with gastrointestinal stromal tumors.2003
- Author(s)
  Kinoshita K, Isozaki K, Tsutsui S, Kitamura S, Hiraoka S, Watabe K, Nakahara M, Nagasawa Y, Kiyohara T, Miyazaki Y, Hirota S, Nishida T, Shinomura Y, Matsuzawa Y
- Journal Title
  
  Eur J Gastroenterol Hepatol. 15(11)
  
  Pages: 1189-1193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Gastrin activates nuclear factor kappaB (NFkappaB) through a protein kinase C dependent pathway involving NFkappaB inducing kinase, inhibitor kappaB (IkappaB) kinase, and tumor necrosis factor receptor associated factor 6 (TRAF6) in MKN-28 cells transfected with gastrin receptor.2003
- Author(s)
  Ogasa M, Miyazaki Y, Hiraoka S, Kitamura S, Nagasawa Y, Kishida O, Miyazaki T, Kiyohara T, Shinomura Y, Matsuzawa Y
- Journal Title
  
  Gut. 52(6)
  
  Pages: 813-819
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Enhanced macrophage responsiveness to lipopolysaccharide and CD40 stimulation in a murine model of inflammatory bowel disease : IL-10-deficient mice.2002
- Author(s)
  Takakura R, Kiyohara T, Murayama Y, Miyazaki Y, Miyoshi Y, Shinomura Y, Matsuzawa Y
- Journal Title
  
  Inflamm Res. 51(8)
  
  Pages: 409-415
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Epidermal growth factor inhibits the growth of TE8 esophageal cancer cells through the activation of STAT1.2002
- Author(s)
  Ichiba M, Miyazaki Y, Kitamura S, Kiyohara T, Shinomura Y, Matsuzawa Y
- Journal Title
  
  J Gastroenterol. 37(7)
  
  Pages: 498-503
- NAID
  50000581934
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Significance of the association between heparin-binding epidermal growth factor-like growth factor and CD9 in human gastric cancer.2002
- Author(s)
  Murayama Y, Miyagawa J, Shinomura Y, Kanayama S, Isozaki K, Yamamori K, Mizuno H, Ishiguro S, Kiyohara T, Miyazaki Y, Taniguchi N, Higashiyama S, Matsuzawa Y
- Journal Title
  
  Int.J.Cancer 98(4)
  
  Pages: 505-513
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181
[Journal Article] Deficiency of KIT positive cells in the colon of patients with diabetes mellitus.2002
- Author(s)
  Nakahara M, Isozaki K, Hirota S, Vanderwinden JM, Takakura R, Kinoshita K, Miyagawa J, Chen H, Miyazaki Y, Kiyohara T, Shinomura Y, Matsuzawa Y
- Journal Title
  
  J.Gastroenterol.Hepatol. 17(6)
  
  Pages: 666-670
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370181

1. SHINOMURA Yasuhisa (90162619)

# of Collaborated Projects: 9 results

# of Collaborated Products: 9 results
2. KIYOHARA Tatsuya (50322178)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
3. KANAYAMA Shuji (40185913)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. MURAYAMA Yoko

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KITAMURA Shinji

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KONDO Shinya

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 東本好文 (60260634)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. TSUTSUI Syusaku

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. FUJIMOTO Takashi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中原征則

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 上山晴美

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIYAZAKI Yoshiji 宮崎 義司

Research Projects

Research Products

Co-Researchers

新規癌転移関連分子Mlzeの機能解析-消化器癌の転移における役割-

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Interaction of proinflammatory cytokines and growth factors in gastric carcinogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a new therapy of Chohn's disease by the regulation of Macrophage/Monocyte function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of NF-kappaB in the growth, differentiation and apoptosis of gastric epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effect of gain-of-function mutation of c-kit on apoptosis in gastrointestinal mesenchymal cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel therapeutics targeting the function of intestinal cells of Cajal in gastrointestinal motility disorder

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of PPARγ in the growth, differentiation and apoptosis of gastrointestinal epithelial cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research on the abnormal expressions of bcl-xL and bak in gastrointestinal cancers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of EGF receptor in the growth, differentiation and apoptosis resistance of gastrointestinal epithelial cells.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Gefitinib (‘Iressa', ZD1839) inhibits SN38-triggered EGF signals and IL-8 production in gastric cancer cells.2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] CD9-mediated activation of the p46 Shc isoform leads to apoptosis in cancer cells.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Helicobacter pylori-induced enlarged-fold gastritis is associated with increased mutagenicity of gastric juice, increased oxidative DNA damage, and an increased risk of gastric carcinoma.2003

Author(s)

Journal Title

Description

Data Source

[Journal Article] Endoscopic ultrasonography-guided fine needle aspiration biopsy in follow-up patients with gastrointestinal stromal tumors.2003

Author(s)

Journal Title

Description

Data Source

Author(s)

Journal Title

MIYAZAKI Yoshiji 宮崎義司