SAKURAI Eiji 櫻井英二

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櫻井英二サクライエイジ

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Researcher Number	30305528
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Affiliation (based on the past Project Information) *help	2010: 名古屋市立大学, 大学院・医学研究科, 講師 2007 – 2008: 名古屋市立大学, 大学院・医学研究科, 講師 2006: 名古屋市立大学, 医学研究科, 講師 2005 – 2006: 名古屋市立大学, 大学院医学研究科, 講師 2005: 名古屋市立大学, 大学院・医学研究科, 講師 2002: 名古屋市立大学, 大学院・医学研究科, 助手 1998 – 2001: 名古屋市立大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology Except Principal Investigator Ophthalmology / Ophthalmology
Keywords	Principal Investigator ドラッグデリバリーシステム / siRNA / マクロファージ / 白血球接着分子 / 加齢黄斑変性 / 脈絡膜新生血管 / 生体分子 / 発現抑制 / 強膜プラグ / 実験的ぶどう膜炎 … More / FK506 / 硝子体 / ナノスフェアー / 網膜 / 硝生体 … More Except Principal Investigator 脈絡膜新生血管 / 加齢黄斑変性 / apoptosis / 細胞死 / アポトーシス / 眼先天異常 / 白血球 / 網膜微小循環 / 網膜色素上皮 / 動物モデル / 家兔 / ドルーゼン / 眼細胞生物学 / siRNA / ドラッグデリバリー / 硝子体 / TNF-a / retinal microcirculation / leukocyte / ぶどう膜炎 / 糖尿病網膜症 / TNF-α / TUNEL method / cell death / lens development / レチノイン酸 / 催奇形因子 / アペトシース制御因子 / TUNEL法 / 水晶体発生 / hyaluronan / developmental abnormalities of the vitreous / faulty separation of the lens vesicle / faulty closure of the embryonic fissure / mouse fetuses / congenital anomalies of the eye / normal eye development / 成立機序 / ヒアルロン酸 / 硝子体形成異常 / 水晶体胞分離不全 / 胎生裂閉鎖不全 / マウス胎仔 / 眼正常発生 / sclera / retina / vitreous / biodegradable polymer / drug delivery system / 5-フルオロウラシル / 生体分解高分子 / 強膜プラグ / カニクイザル / ポリ乳酸 / 生体分解性高分子 / 好中球エラスターゼ / CCR3 / レクチン / 実験的脈絡膜新生血管 / レーザー / SPARC / VEGF-A / 眼底自発蛍光 / リポフスチン / ドラッグターゲティング / 家兎 / 脈略膜新生血管 / ドラッグデリバリーシステム / lipofectamine / ICAM-1 / 網膜血管内皮 / フルオレセイン / ナノスフェアー Less

The role of neutrophil elastase on the disturbance of retinal microcirculation
- Principal Investigator
  
  YOSHIDA Munenori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Elucidation of the pathogenesis of avascularity in the macula viavascular- and molecular -biological approach
- Principal Investigator
  
  NOZAKI Miho
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Development of New Drug Delivery Systems to Target Vascular Endothelial Growth Factor in Age -Related Macular Degeneration
- Principal Investigator
  
  OGURA Yuichiro
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Development of a New Rabbit Model of Age-Related Macular Degeneration
- Principal Investigator
  
  YASUKAWA Tsutomu
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
siRNA含有ナノスフェアーによる網膜血管内皮細胞の遺伝子発現制御
- Principal Investigator
  
  小椋祐一郎
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
siRNAを用いた血管内皮接着分子抑制による脈絡膜新生血管の治療の開発Principal Investigator
- Principal Investigator
  
  櫻井英二
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Study on the molecular mechamisms of leukocyte stasis in retinal microcirculation abnormality-possible roles of TNF-a
- Principal Investigator
  
  YOSHIDA Munenori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  NAGOYA CITY UNIVERSITY
難治ぶどう膜炎に対する免疫抑制剤硝子体内送達システムの開発に関する実験的研究Principal Investigator
- Principal Investigator
  
  桜井英二
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
Role of apoptosis regulative factor during development of ocular structures
- Principal Investigator
  
  MATSUNAGA Noriko
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  NAGOYA CITY UNIVERSITY
高分子ナノスフェアーの眼内動態の薬物動態学的評価Principal Investigator
- Principal Investigator
  
  桜井英二
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
生体分解性高分子ナノスフェアーによる網膜組織への遺伝子導入に関する基礎的研究
- Principal Investigator
  
  OGURA Yuichiro
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University
ROLES OF APOPTOSIS IN NORMAL AND ABNORMAL EYE DEVELOPMENTS
- Principal Investigator
  
  OZEKI Hironori
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  NAGOYA CITY UNIVERSITY
Development of Vitreal Drug Delivery System with Biodegradable Polymeric Scleral Plug
- Principal Investigator
  
  OGURA Yuichiro
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Nagoya City University

All 2010 2008 2007 2006

All Journal Article Presentation

[Journal Article] Suppression of ICAM-1 in retinal and choroidal endothelial cells by plasmid small-interfering RNAs in vivo.2010
- Author(s)
  Hirano Y, Sakurai E, Matsubara A, Ogura Y.
- Journal Title
  
  Invest Ophthalmol Vis Sci. 51
  
  Pages: 508-515
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20592053
[Journal Article] Sequence- and target-independent2008
- Author(s)
  Kleinman ME, Yamada K, Takeda A, Chandrasekaran V, Nozaki M, Baffi JZ, Albuquerque RJ, Yamasaki S, Itaya M, Pan Y, Appukuttan B, Gibbs D, Yang Z, Kariko K, Ambati BK, Wilgus TA, DiPietro LA, Sakurai E, Zhang K, Smith JR, Taylor EW, Ambati J
- Journal Title
  
  angiogenesis suppression by siRNA via TLR3 452(7187)
  
  Pages: 591-597
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592032
[Journal Article] Upregulation of VEGF in murine retina via monocyte recruitment after retinal scatter laser photocoagulation2007
- Author(s)
  Itaya M, Sakurai E, Nozaki M, Yamada K, Yamasaki S, Asai K, Ogura Y
- Journal Title
  
  Invest Ophthalmol Vis Sci 48(12)
  
  Pages: 5677-5683
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592032
[Journal Article] Drug delivery from ocular implants2006
- Author(s)
  Yasukawa T, Ogura Y, Kimura H, Sakurai E, Tabata Y.
- Journal Title
  
  Expert Opin Drug Deliv 3
  
  Pages: 261-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591929
[Journal Article] Drug delivery from ocular implants2006
- Author(s)
  Yasukawa T, Ogura Y, Kimura H, Sakurai E, Tabata Y
- Journal Title
  
  Expert Opin Drug Deliv 3
  
  Pages: 261-273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390471
[Presentation] Long-term outcome of radiation therapy for exudative age-related macular degeneration in Japanese patients2008
- Author(s)
  Yasukawa T, Tokoro M, Sakurai E, Yoshida M, Ogura Y.
- Organizer
  Would Ophthalmology Congress (WOC) 2008
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-18591929
[Presentation] Long-term outcome of radiation therapy for exudative age-related macular degeneration in Japanese patients2008
- Author(s)
  Yasukawa T, Tokoro M, Sakurai E, Yoshida M, Ogura Y
- Organizer
  Would Ophthalmology Congress(WOC)2008
- Place of Presentation
  Hong Kong, China
- Data Source
  KAKENHI-PROJECT-18390471
[Presentation] Suppression of ICAM-1 in Murine retina by plasmid interfering RNAs2008
- Author(s)
  Hirano Y, Sakurai E, Matsubara A, Ogura Y
- Organizer
  2008 Annual Meeting of the Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, USA
- Year and Date
  2008-05-01
- Data Source
  KAKENHI-PROJECT-18390471

1. OGURA Yuichiro (70191963)

# of Collaborated Projects: 10 results

# of Collaborated Products: 7 results
2. YOSHIDA Munenori (60273447)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
3. OZEKI Hironori (60254299)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. YASUKAWA Tsutomu (00324632)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
5. NOZAKI Miho (00295601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. TAMAI Kazushi (40188412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIRAI Shoichiro (30080063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. MATSUNAGA Noriko (20315906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 倉知豪 (80405159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OHATA Atsutoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKURAI Eiji 櫻井 英二

櫻井 英二 サクライ エイジ

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siRNAを用いた血管内皮接着分子抑制による脈絡膜新生血管の治療の開発Principal Investigator

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難治ぶどう膜炎に対する免疫抑制剤硝子体内送達システムの開発に関する実験的研究Principal Investigator

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高分子ナノスフェアーの眼内動態の薬物動態学的評価Principal Investigator

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[Journal Article] Suppression of ICAM-1 in retinal and choroidal endothelial cells by plasmid small-interfering RNAs in vivo.2010

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[Journal Article] Sequence- and target-independent2008

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SAKURAI Eiji 櫻井英二

櫻井英二サクライエイジ