Munakata Mitsutoshi 宗形光敏

… Alternative Names

Researcher Number	30312573
Other IDs
Affiliation (Current)	2020: 東北大学, 医学系研究科, 非常勤講師
Affiliation (based on the past Project Information) *help	2020: 東北大学, 医学系研究科, 非常勤講師 2016 – 2018: 東北大学, 医学系研究科, 非常勤講師 2012 – 2015: 東北大学, 医学(系)研究科(研究院), 非常勤講師 2010 – 2012: 東北大学, 大学院・医学系研究科, 非常勤講師 2010: 東北大学, 医学系・研究科, その他 … More
Review Section/Research Field	Principal Investigator Pediatrics / Pediatrics / Rehabilitation science/Welfare engineering / Basic Section 52050:Embryonic medicine and pediatrics-related Except Principal Investigator Pediatrics / Kidney internal medicine / Pediatrics
Keywords	Principal Investigator Menkes病 / Macular mouse / 銅錯体 / ATP7A / 銅 / macular mouse / Ｍｅｎｋｅｓ病 / 電気生理 / パッチクランプ法 / 皮質形成異常 … More Except Principal Investigator 移植・再生医療 / 細胞・組織 / 大脳皮質形成異常 / パッチクランプ法 / 接着因子 / 免疫組織化学 / エリスロポイエチン / 酸素濃度 / 尿中落下細胞培養系 / 微小単離尿細管灌流 / 近位尿細管 / 生理学 / タンパク質 / 発生・分化 / 微小単離尿細管灌流法 / 嚢胞腎 / 経上皮電位 / アポトーシス / 中心繊毛 / 管腔内圧 / ヘンレの太い上行脚 / 皮質部集合管 / ARPKD / PCKラット / 徴小単離尿細管灌流 / 抗利尿ホルモン / ヘンレループ / 慢性腎不全 / 腎尿細管 / 医療・福祉 / 解剖学 / 病理学 / 腎嚢胞 / イオン輸送 / イオンチャンネル / 絨毛 / 小児末期腎不全 / 利尿薬 / 多嚢胞腎 / 集合管 / 中枢ヒスタミン / ヒスタミンH1受容体 / ヒスタミンH3受容体 / けいれん / 内因性ヒスタミン / H3受容体阻害薬 / 覚醒反応 / キンドリング / ペンチレンテトラゾール / thioperamide / central histamine / histamine H1 receptor / histamine H3 receptor / convulsion / intrinsic histamine / histamine H3 receptor antagonist / waking reaction / 熱性けいれん / Na+チャネル / K+チャネル / 電位依存性 / チャネル異常 / パッチクランプ / 温度変化 / 抗ヒスタミン薬 / NA+チャネル / Na^+チャネル / K^+チャネル / チャネル以上 / Febrile seizure / sodium channel / potassium channel / voltage-gated / abnormal channel / temperature change / antihistaminic agents / patch clamp / 抗カルジオリピン抗体 / てんかん / 点頭てんかん / 抗カルジオリピン杭体 / western blottin / 免疫細織化学 / Eplepsy / West syndrome / anti-cardiolipin antibody Less

有機銅錯体－循環型キレート剤混合ミセルを用いたMenkes病治療薬の展開Principal InvestigatorOngoing
- Principal Investigator
  
  宗形光敏
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tohoku University
Copper supplement therapy based on a developmental change in copper metabolism in Menkes disease.Principal Investigator
- Principal Investigator
  
  Munakata Mitsutoshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
New therapeutic approach using functional copper complexes to treat Menkes disase.Principal Investigator
- Principal Investigator
  
  Munakata Mitsutoshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
A newly developed optical guide system for safe insertion of nasogastric tube.Principal Investigator
- Principal Investigator
  
  MUNAKATA Mitsutoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Tohoku University
Molecular physiological analyses of renal failure in pediatric cystic renal diseases
- Principal Investigator
  
  KONDO Yoshiaki
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Nihon University
  Tohoku University
機能的銅キャリアー分子を用いたメンケス病の治療法開発Principal Investigator
- Principal Investigator
  
  宗形光敏
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
エリスロポイエチン産生機構の尿中酸素濃度感受性仮説の検証
- Principal Investigator
  
  KONDO Yoshiaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tohoku University
Neurophysiological and molecular approach for evaluating mechanism of pathogenesis of febrile seizure
- Principal Investigator
  
  IINUMA Kazuie
- Project Period (FY)
  2002 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  TOHOKU UNIVERSITY
Anticardolipin antibody and childhood epiepsy
- Principal Investigator
  
  HAGINOYA Kazuhiro
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
パッチクランプ法によるヒト大脳皮質異形成組織のてんかん発症の機序の解明Principal Investigator
- Principal Investigator
  
  宗形光敏
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
Research for development of new antiepileptic drug with wake-promoting effect
- Principal Investigator
  
  IINUMA Kazuie
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University
ヒト大脳皮質異形成のてんかん源性獲得に関する組織学的、生理学的研究
- Principal Investigator
  
  HAGINOYA Kazuhiro
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  Tohoku University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Development of a Therapeutic Agent for Menkes Disease: Solubilization of a Copper-Disulfiram Complex2018
- Author(s)
  星佑次郎、谷紀彦、田畑英嗣、若松真太朗、宗形光敏、丸山一雄、児玉浩子、忍足鉄太、夏苅英昭、高橋秀依
- Journal Title
  
  薬学雑誌
  
  Volume: 135 Issue: 3 Pages: 493-499
- DOI
  10.1248/yakushi.14-00188
- NAID
  130004756516
- ISSN
  0031-6903, 1347-5231
- Year and Date
  2018-08-31
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461534
[Journal Article] Menkes disease: Oral administration of glyoxal-bis(N(4)-methylthiosemicarbazonato)-copper(II) rescues the macular mouse2018
- Author(s)
  Munakata Mitsutoshi, Kodama Hiroko, Tani Norihiko, Kimura Kazuhiro, Takahashi Hideyo, Maruyama Kazuo, Sakamoto Yoshimasa, Kure Shigeo
- Journal Title
  
  Pediatric Research
  
  Volume: 84 Pages: 770-777
- DOI
  10.1038/s41390-018-0116-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06762, KAKENHI-PROJECT-16K09959
[Journal Article] In response to letter to Editor by Nosaka et al. on our paper: Elevated serum levels of neutrophil elastase in patients with influenza virus-associated encephalopathy.2017
- Author(s)
  Haginoya K, Sun G, Ota C, Kitaoka S, Takayanagi M, Kitamura T, Uematsu M, Hino-Fukuyo N, Munakata M, Kure S.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 327 Pages: 50-50
- DOI
  10.1016/j.jns.2016.11.041
- Data Source
  KAKENHI-PROJECT-16K09959
[Journal Article] Elevated serum levels of neutrophil elastase in patients with influenza virus-associated encephalopathy.2015
- Author(s)
  Sun G, Ota C, Kitaoka S, Chiba Y, Takayanagi M, Kitamura T, Yamamoto K, Fujie H, Mikami H, Uematsu M, Hino-Fukuyo N, Munakata M, Kure S, Haginoya K.
- Journal Title
  
  J Neurol Sci.
  
  Volume: 349 Pages: 190-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461534
[Journal Article] Reduction in glutamine/glutamate levels in the cerebral cortex after adrenocorticotropic hormone therapy in patients with west syndrome.2014
- Author(s)
  Munakata M, Togashi N, Sakamoto O, Haginoya K, Kobayashi Y, Onuma A, Iinuma K, Kure S.
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume: 232 Pages: 277-283
- NAID
  130004460120
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461534
[Journal Article] Copper-trafficking efficacy of copper-pyruvaldehyde bis(N4- methylthiosemicarbazone) on the macular mouse, an animal model of Menkes disease.2012
- Author(s)
  Munakata M, Kodama H, Fujisawa C, Hiroki T, Kimura K, Watanabe M, Nishikawa M, Tsuchiya S.
- Journal Title
  
  Pediatric Researh
  
  Volume: Vol.72, No.3 Pages: 270-276
- DOI
  10.1038/pr.2012.85
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22500499
[Journal Article] Progressive atrophy of the cerebrum in 2 Japanese sisters with microcephaly with simplified gyri and enlarged extraaxial space2011
- Author(s)
  Hirose M, et al.
- Journal Title
  
  Neuropediatrics
  
  Volume: 42 Pages: 163-166
- DOI
  10.1055/s-0031-1287771
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591312, KAKENHI-PROJECT-21591334, KAKENHI-PROJECT-22500499, KAKENHI-PUBLICLY-23110534
[Journal Article] The nutrient formula containing eicosapentaenoic acid and docosahexaenoic acid benefits the fatty acid status2009
- Author(s)
  Munakata M, 他
- Journal Title
  
  Tohoku J Exp Med 217(1)
  
  Pages: 23-28
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659260
[Journal Article] Olfactory stimulation using black pepper oil facilitates oral feeding in pediatric patients receiving long-term enteral nutrition2008
- Author(s)
  Munakata M, 他
- Journal Title
  
  Tohoku J Exp Med 214(4)
  
  Pages: 327-332
- NAID
  10024167604
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659260
[Journal Article] Residual effect of a 7-amino metabolite of clonazepam on GABAA receptor function in the nucleus reticularis thalami of the rat2008
- Author(s)
  Munakata M, 他
- Journal Title
  
  Epilepsia 49(10)
  
  Pages: 1803-1808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659260
[Journal Article] Residual effect of a 7-amino metabolite of clonazepam on GABA_A recept or function in the nucleus reticularis thalami of the rat.2008
- Author(s)
  Munakata Mitsutoshi, et. al.
- Journal Title
  
  Epilepsia
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19659260
[Presentation] メンケス病モデル動物マクラマウスにおける CuGTSM の体内動態の検討2018
- Author(s)
  小林昌平、川上武昭、阪本優介、宗形光敏、児玉浩子、高橋秀依、中村悠輔、山岸喜彰、工藤敏之、伊藤清美
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-16K09959
[Presentation] Menkes病モデルマウス(Macular mouse)に対する有機銅錯体の経口投与の効果について2018
- Author(s)
  宗形光敏、児玉浩子、谷紀彦、木村和彦、髙橋秀依、坂本吉正、呉繁夫
- Organizer
  第22回日本ウイルソン病研究会
- Data Source
  KAKENHI-PROJECT-16K09959
[Presentation] Menkes病モデルマウスに対する有機銅錯体経口投与による治療効果の検討2016
- Author(s)
  宗形光敏、児玉浩子、谷紀彦、木村和彦、高橋英依、丸山一雄、呉繁夫
- Organizer
  第58回日本先天代謝異常学会総会
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K09959
[Presentation] Studies on Cu complexes as therapeutic drugs for Menkes disease2013
- Author(s)
  Hideyo Takahashi, Paiku Soong-a, Yujiro Hoshi, Norihiko Tani, Hideaki Natsugari, Mutsumi Seki, Ryo Suzuki, Kazuo Maruyama, Mitsutoshi Munakata, Tomoko Hiroki, Hiroko Kodama
- Organizer
  The 10th conference for ISTERH (international society for trace element research in humans)
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25461534
[Presentation] Menkes病治療薬としての銅錯体の創出2013
- Author(s)
  ペク・スンア，星祐次郎，谷紀彦，田畑英嗣，関むつみ，鈴木亮，丸山一雄，宗形光敏，廣木伴子，児玉浩子，夏苅英昭，高橋秀依
- Organizer
  第57回日本薬学会関東支部大会
- Place of Presentation
  板橋、東京
- Data Source
  KAKENHI-PROJECT-25461534
[Presentation] カテーテル誤挿入防止用光ファイバライトガイドの開発2013
- Author(s)
  岡田祐太郎、宗形光敏、松浦祐司
- Organizer
  平成25 年東北地区若手研究者研究発表会
- Place of Presentation
  仙台
- Year and Date
  2013-03-01
- Data Source
  KAKENHI-PROJECT-22500499
[Presentation] 体内に光源を配置した透過光検出の検討2011
- Author(s)
  日野真弓、宗形光敏、松浦祐司
- Organizer
  レーザ学会学術講演会第32回年次大会
- Place of Presentation
  仙台
- Year and Date
  2011-02-01
- Data Source
  KAKENHI-PROJECT-22500499
[Presentation] 栄養導入カテーテル挿入補助用光ファイバライトガイドの製作2011
- Author(s)
  日野真弓、宗形光敏、松浦祐司
- Organizer
  第50回日本生体医工学学会大会
- Place of Presentation
  東京
- Year and Date
  2011-05-01
- Data Source
  KAKENHI-PROJECT-22500499
[Presentation] 栄養導入カテーテルの誤挿入防止のための光ファイバライトガイドの作製2010
- Author(s)
  日野真弓、宗形光敏、馬鱗、松浦祐司
- Organizer
  電気関係学会東北支部連合大会
- Place of Presentation
  八戸
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22500499
[Presentation] 栄養導入カテーテルの誤挿入防止のための光ファイバライトガイドの作製2010
- Author(s)
  日野真弓、宗形光敏、馬鱗、松浦祐司
- Organizer
  電気関係学会東北支部連合大会
- Place of Presentation
  八戸工業大学
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-22500499

1. HAGINOYA Kazuhiro (00208414)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
2. KODAMA Hiroko (00093386)

# of Collaborated Projects: 4 results

# of Collaborated Products: 7 results
3. YOKOYAMA Hiroyuki (40271952)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. OHURA Toshihiro (10176828)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. FUJIWARA Ikuma (10271909)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. KONDO Yoshiaki (00221250)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. UCHIDA Shinichi (50262184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. IINUMA Kazuie (80004927)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. MATSUURA Yuji (10241530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
10. UEMATSU Mitsugu (90400316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. KURE Shigeo (10205221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 菊池敦生 (30447156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高橋秀依 (10266348)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. MASUDA Yoshinobu

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Munakata Mitsutoshi 宗形 光敏

宗形 光敏 ムナカタ ミツトシ

MUNAKATA Mitsutoshi 宗形 光敏

Research Projects

Research Products

Co-Researchers

有機銅錯体－循環型キレート剤混合ミセルを用いたMenkes病治療薬の展開Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Copper supplement therapy based on a developmental change in copper metabolism in Menkes disease.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New therapeutic approach using functional copper complexes to treat Menkes disase.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A newly developed optical guide system for safe insertion of nasogastric tube.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular physiological analyses of renal failure in pediatric cystic renal diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

機能的銅キャリアー分子を用いたメンケス病の治療法開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

エリスロポイエチン産生機構の尿中酸素濃度感受性仮説の検証

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Neurophysiological and molecular approach for evaluating mechanism of pathogenesis of febrile seizure

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Anticardolipin antibody and childhood epiepsy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

パッチクランプ法によるヒト大脳皮質異形成組織のてんかん発症の機序の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for development of new antiepileptic drug with wake-promoting effect

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒト大脳皮質異形成のてんかん源性獲得に関する組織学的、生理学的研究

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Development of a Therapeutic Agent for Menkes Disease: Solubilization of a Copper-Disulfiram Complex2018

Author(s)

Munakata Mitsutoshi 宗形光敏

宗形光敏ムナカタミツトシ

MUNAKATA Mitsutoshi 宗形光敏