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Morisaki Hirobumi  森崎 弘史

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MORISAKI Hirobumi  森崎 弘史

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Researcher Number 30317581
Other IDs
External Links
Affiliation (Current) 2025: 昭和医科大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help 2023 – 2024: 昭和大学, 歯学部, 講師
2017 – 2020: 昭和大学, 歯学部, 講師
2011 – 2012: 昭和大学, 歯学部, 講師
2006 – 2008: 昭和大学, 歯学部, 講師
2001 – 2004: 昭和大学, 歯学部, 助手
Review Section/Research Field
Principal Investigator
Morphological basic dentistry / Morphological basic dentistry
Except Principal Investigator
Basic Section 57020:Oral pathobiological science-related / 病態科学系歯学(含放射線系歯学) / Morphological basic dentistry / Morphological basic dentistry
Keywords
Principal Investigator
感染症 / 核酸 / 細菌 / Streptococcus oralis / csRNA / Streptococcus sanguinis / Streptococcus pneumoniae / Streptococcus / choline binding protein / Streptococcus mitis … More / choline-binding protein E / 歯周病原菌 / 細胞膨化致死毒素 / Cytolethal Distending Toxin / Actinobacillus actinomycetemcomitans / デキストラナーゼ / ムタナーゼ / Prevotella oralis … More
Except Principal Investigator
Streptococcus mutans / Cell wall anchoring / LPXTG motif / バイオフィルム / Sortase / Surface protein antigen / Glucan-binding protein C / Dextranase / デンタルプラーク / Cell Wall Anchoring / LPXTGモチーフ / 表層蛋白抗原 / グルカン結合蛋白質 / デキストラナーゼ / ソーターゼ / 口腔細菌 / IgA / 口腔内細菌叢 / 唾液腺 / 自然免疫 / ディスバイオーシス / 常在細菌叢 / 誤嚥性肺炎 / BIofilm / Glucan Binding Protein / Sruface Protein Antigen / グルカン結合蛋白質C / Biofilm / 表層蛋白質 / Sorting signal / う蝕予防 / ショ糖非依存性付着 / ショ糖依存性付着 / 齲蝕 / フルクタン / Fructosidase / Streptococcus gordonii / Streptococcus sobrinus / グルカン依存性凝集 / グルカン結合タンパク質 / バイオフィルム感染症 / 感染予防 / LPXTG蛋白質 / 齲蝕細菌 / 口腔レンサ球菌 Less
  • Research Projects

    (9 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (8 People)
  •  マウスモデルにおける誤嚥性肺炎と常在細菌叢の肺-腸管クロストークの解析

    • Principal Investigator
      桑田 啓貴
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Showa University
  •  口腔内細菌に対する唾液腺のB細胞恒常性維持メカニズムの解明

    • Principal Investigator
      黒澤 実愛
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57020:Oral pathobiological science-related
    • Research Institution
      Showa University
  •  Elucidation of the regulatory mechanisms for bacterial virulence with small RNAs.Principal Investigator

    • Principal Investigator
      Morisaki Hirobumi
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Basic researches on the restraint method development of the drug-resistant gene transmissionPrincipal Investigator

    • Principal Investigator
      MORISAKI Hirobumi
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Basic study for development of new treatment and prevention against infectious disease by pathogenic bacteria

    • Principal Investigator
      IGARASHI Takeshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  歯周病原菌が産生する細胞膨化致死毒素の作用機序Principal Investigator

    • Principal Investigator
      森崎 弘史
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Proteome Analysis of Surface Protein of Cariogenic Bacteria Influenced to Formation of Biofilm

    • Principal Investigator
      GOTO Nobuichi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University
  •  Influence to Biofilm Infection of Surface Protein Mediated by Sortase in Cariogenic Bacteria

    • Principal Investigator
      IGARASHI Takeshi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Showa University
  •  水不溶性グルカン分解酵素の遺伝子クローニングとその解析Principal Investigator

    • Principal Investigator
      森崎 弘史
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Showa University

All 2023 2019 2018 2017 2012 2007 2006 2004

All Journal Article Presentation

  • [Journal Article] Severity of acute lung injury in aspiration pneumonia model mice transplanted with human oral microflora2023

    • Author(s)
      Hayashi Manami、Mori Mina、Itsumi Momoe、Nakamura Natsuno、Takaki Takashi、Onoyama Kaoru、Fukamachi Haruka、Kurosawa Mie、Morisaki Hirobumi、Funatsu Takahiro、Myers Mie、Iijima Takehiko、Kuwata Hirotaka
    • Journal Title

      Oral Science International

      Volume: 21 Issue: 1 Pages: 121-130

    • DOI

      10.1002/osi2.1198

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K09144
  • [Journal Article] Streptococcus sanguinis non-coding csRNAs negatively regulate expression of type IV pilus retraction ATPase PilT and biofilm formation2018

    • Author(s)
      Ota C, Morisaki H, Nakata M, Arimoto T, Fukamachi H, Kataoka H, Masuda Y, Suzuki N, Miyazaki T, Okahashi N, Kuwata H
    • Journal Title

      Infect Immun

      Volume: 86 Issue: 3 Pages: 1-13

    • DOI

      10.1128/iai.00894-17

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11610, KAKENHI-PROJECT-17K11627, KAKENHI-PROJECT-17K11628, KAKENHI-PROJECT-17K11958, KAKENHI-PROJECT-17K19751, KAKENHI-PROJECT-15KK0306, KAKENHI-PROJECT-17H04369, KAKENHI-PROJECT-18K19643, KAKENHI-PROJECT-18K09558
  • [Journal Article] Streptococcus mutansのバイオフィルム形成におけるSortaseの役割2007

    • Author(s)
      五十嵐武, 森崎弘史, 高橋真和, 櫨場八裕
    • Journal Title

      日本細菌学雑誌 62巻・1号(印刷中)

    • NAID

      10019310264

    • Data Source
      KAKENHI-PROJECT-18592009
  • [Journal Article] Role of sortase in biofilm formation of Streptococcus mutans2007

    • Author(s)
      Haseba Y, Morisaki H, Takahashi M, Igarashi T
    • Journal Title

      Dentistry in Japan 43

      Pages: 16-22

    • NAID

      10021953197

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Journal Article] Role of sortase in biofilm formation of Streptococcus mutans2007

    • Author(s)
      Haseba Y., Morisaki H., Takahashi M., Ikarashi T.
    • Journal Title

      Dentistry in Japan 43巻

      Pages: 1-7

    • NAID

      10021953197

    • Data Source
      KAKENHI-PROJECT-18592009
  • [Journal Article] Cell wall anchoring of WapA and FruA in Streptococcus mutans2006

    • Author(s)
      Igarashi T., Morisaki H.
    • Journal Title

      Journal of Dental Research 85巻

    • Data Source
      KAKENHI-PROJECT-18592009
  • [Journal Article] Streptococcus mutansのう蝕原性バイオフィルム形成はDextranase産生菌との共培養により抑制される2006

    • Author(s)
      森崎弘史, 栗原華絵子, 有本隆文, 櫨場八裕, 五十嵐 武
    • Journal Title

      Journal of Oral Biosciences 48巻

      Pages: 206-206

    • Data Source
      KAKENHI-PROJECT-18592009
  • [Journal Article] Actinobacillus actinomycetemcomitansの細胞致死膨化毒素の毒性に関する基礎研究2004

    • Author(s)
      森崎 弘史, 五十嵐 武
    • Journal Title

      昭和歯学会雑誌 24・3

      Pages: 255-260

    • NAID

      10017406984

    • Data Source
      KAKENHI-PROJECT-15791048
  • [Presentation] Klebsiellaのマンノースホスホトランスフェラーゼシステムは腸管定着関連因子である2023

    • Author(s)
      三木 優、深町 はるか、逸見 百江、森崎 弘史、黒澤 実愛、桑田 啓貴
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K09144
  • [Presentation] 口腔内細菌叢は口腔粘膜での好中球の末梢分化に関与している2023

    • Author(s)
      逸見 百江、Natasa Trtic、森 美菜、松井 庄平、中村 夏野、深町 はるか、黒澤 実愛、森崎 弘史、桑田 啓貴
    • Organizer
      第65回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-23K09144
  • [Presentation] Streptococcus sanguinisのcsRNAによるⅣ型線毛pilT遺伝子の発現制御2019

    • Author(s)
      森崎 弘史
    • Organizer
      第51回レンサ球菌研究会
    • Data Source
      KAKENHI-PROJECT-17K11627
  • [Presentation] Regulation of type IV pilus retraction ATPase pilT by small noncoding RNAs in Streptococcus sanguinis2017

    • Author(s)
      Chiaki Ota, Hirobumi Morisaki, Takafumi Arimoto, Haruka Fukamachi, Hideo Kataoka, Yoshiko Masuda, Noriyuki Suzuki, Takashi Miyazaki,Hirotaka Kuwata
    • Organizer
      第65回国際歯科研究学会日本部会総会・学術大会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K11627
  • [Presentation] Streptococcus sanguinisのノンコーディングcsRNAはⅣ型線毛pilT遺伝子の発現を負に制御し、バイオフィルム形成を抑制する2017

    • Author(s)
      大田 千明、森崎 弘史、有本 隆文、深町 はるか、片岡 嗣雄、増田 宜子、鈴木 規元、宮﨑 隆、桑田 啓貴
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K11627
  • [Presentation] Streptococcus mitisのcholine binding protein E欠損株の性状2012

    • Author(s)
      森崎弘史、有本隆文、片岡嗣雄、谷口誠、深町はるか
    • Organizer
      第54回歯科基礎医学会学術大会
    • Place of Presentation
      奥羽大学
    • Year and Date
      2012-09-16
    • Data Source
      KAKENHI-PROJECT-23792114
  • [Presentation] Streptococcus mitisのcholine binding protein E欠損株の性状2012

    • Author(s)
      森崎 弘史
    • Organizer
      第54回 歯科基礎医学会 学術大会
    • Place of Presentation
      奥羽大学
    • Data Source
      KAKENHI-PROJECT-23792114
  • [Presentation] Dextranase産生菌によるStreptococcus mutansの齲蝕原性バイオフィルム形成の抑制2007

    • Author(s)
      森崎弘史、栗原華絵子、有本隆文、五十嵐武
    • Organizer
      昭和大学歯学部ハイテクリサーチセンター平成18年度研究成果発表会
    • Place of Presentation
      東京
    • Year and Date
      2007-03-17
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Streptococcus mutansのバイオフィルム形成におけるSortaseの役割2007

    • Author(s)
      五十嵐武、森崎弘史、高橋真和、櫨場八裕
    • Organizer
      第80回日本細菌学会総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Streptococcus gordonii Challis株のNucleaseの解析2007

    • Author(s)
      栗原華絵子、有本隆文、深町はるか、森崎弘史、櫨場八裕、五十嵐武
    • Organizer
      第49回歯科基礎医学会
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Streptococcus gordoniiのFruA遺伝子ホモログの分子生物学的解析2006

    • Author(s)
      栗原華絵子、森崎弘史、有本隆文、五十嵐武
    • Organizer
      第26回昭和歯学会総会
    • Place of Presentation
      東京
    • Year and Date
      2006-07-22
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Streptococcus gordoniiのdextranase発現系の構築と齲蝕予防への応用に関する基礎研究2006

    • Author(s)
      森崎弘史、栗原華絵子、有本隆文、深町はるか、平尾衣都子、五十嵐武
    • Organizer
      昭和大学歯学部30周年記念講演会
    • Place of Presentation
      東京
    • Year and Date
      2006-11-04
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Cell wall anchoring of WapA and FruA in Streptococcus mutans2006

    • Author(s)
      Igarashi T, Morisaki H
    • Organizer
      84th International Association for Dental Research
    • Place of Presentation
      Brisbane
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Streptococcus mutansの齲蝕原性バイオフィルム形成はDextranase産生菌との共培養により抑制される2006

    • Author(s)
      森崎弘史、栗原華絵子、有本隆文、櫨場八裕、五十嵐武
    • Organizer
      48回歯科基礎医学会
    • Place of Presentation
      鶴見
    • Data Source
      KAKENHI-PROJECT-18592009
  • [Presentation] Streptococcus gordonii Challis株のNucleaseホモログの解析2006

    • Author(s)
      栗原華絵子、森崎弘史、有本隆文、高橋真和、五十嵐武
    • Organizer
      第48回歯科基礎医学会
    • Place of Presentation
      鶴見
    • Data Source
      KAKENHI-PROJECT-18592009
  • 1.  IGARASHI Takeshi (10159585)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 2.  桑田 啓貴 (60380523)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 3.  ARIMOTO Takafumi (60407393)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 4.  GOTO Nobuichi (10077175)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  深町 はるか (10433799)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  宮久保 あや子 (50643706)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  黒澤 実愛 (70815802)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 8.  NAKATA Masanobu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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