Yotsumoto Satoshi 四元聡志

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YOTSUMOTO Satoshi 四元聡志

YOTHUMOTO Satoshi 四元聡志

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Researcher Number	30318191
Other IDs
Affiliation (Current)	2025: 東京薬科大学, 生命科学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 東京薬科大学, 生命科学部, 助教 2010 – 2011: 東京医科歯科大学, 難治疾患研究所, 特任助教 2008: Akita University, 大学院・医学系研究科, COE研究員 2008: Akita University, 大学院医学系研究科, COE 研究員 2007: Tokyo University of Pharmacy and Life Science, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords	Principal Investigator チロシンキナーゼ / 好中球エラスターゼ / ミエロペルオキシダーゼ / 酸化リン脂質 / 脂質酸化 / 好中球細胞外トラップ / 好中球 / 再発 / 制御性単球 / 単球 … More / がん治療 / cDC / pDC / IL-27 / SOCS1/3 / mobilization / ウイルス感染 / Type II IFN / Type I IFN / ウィルス感染 / 細胞周期 / インターフェロン / 樹状細胞 / 造血幹細胞 / ワクチン / マクロファージ / キャリアー / DNA-PKcs / IL-10 / IL-12 / CpG-ODN / リポソーム Less

Development of cancer treatments targeting regulatory monocytesPrincipal Investigator
- Principal Investigator
  
  四元聡志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Analysis of molecular mechanisms of lipid peroxidation-dependent NET formationPrincipal Investigator
- Principal Investigator
  
  Yotsumoto Satoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Tokyo University of Pharmacy and Life Science
Regulation of hematopoietic stem cell activation by dendritic cellsPrincipal Investigator
- Principal Investigator
  
  YOTSUMOTO Satoshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tokyo Medical and Dental University
The design of liposomal carriers for CpG-ODNPrincipal Investigator
- Principal Investigator
  
  YOTHUMOTO Satoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Akita University
  Tokyo University of Pharmacy and Life Science

All 2021 2020 2019 2011 2008

All Journal Article Presentation Book

[Book] 免疫の事典「IL-15」2011
- Author(s)
  四元聡志, 樗木俊聡(分担)
- Total Pages
  488
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-22790054
[Book] 免疫の事典「IL-15」2011
- Author(s)
  四元聡志,樗木俊聡(分担)
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-22790054
[Journal Article] Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation2021
- Author(s)
  Tokuhiro Takuto、Ishikawa Akane、Sato Haruka、Takita Shunya、Yoshikawa Ayuri、Anzai Ryoko、Sato Shinichi、Aoyagi Ryohei、Arita Makoto、Shibuya Takumi、Aratani Yasuaki、Shimizu Shigeomi、Tanaka Masato、Yotsumoto Satoshi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 9 Pages: 718586-718586
- DOI
  10.3389/fcell.2021.718586
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-WRAPUP-20H05613, KAKENHI-PLANNED-17H06414, KAKENHI-PROJECT-21H05029, KAKENHI-PROJECT-20H00495, KAKENHI-PROJECT-20K06446, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H00467, KAKENHI-PROJECT-20H03473, KAKENHI-PROJECT-19K08894
[Journal Article] Garcinielliptone G from Garcinia subelliptica Induces Apoptosis in Acute Leukemia Cells2021
- Author(s)
  Yun YoungSook、Shioura Mariko、Hitotsuyanagi Yukio、Yotsumoto Satoshi、Takahashi Yuji、Aoyagi Yutaka、Kinoshita Takeshi、Takeya Koichi、Inoue Hideshi
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 9 Pages: 2422-2422
- DOI
  10.3390/molecules26092422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08894
[Journal Article] Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor2021
- Author(s)
  Shibuya Takumi、Kamiyama Asami、Sawada Hirotaka、Kikuchi Kenta、Maruyama Mayu、Sawado Rie、Ikeda Naoki、Asano Kenichi、Kurotaki Daisuke、Tamura Tomohiko、Yoneda Atsuko、Imada Keisuke、Satoh Takashi、Akira Shizuo、Tanaka Masato、Yotsumoto Satoshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 663115-663115
- DOI
  10.3389/fimmu.2021.663115
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06563, KAKENHI-PROJECT-21K06877, KAKENHI-PROJECT-21K19387, KAKENHI-PROJECT-20H03473, KAKENHI-PROJECT-19K08894
[Journal Article] Frontline Science:?Conversion of neutrophils into atypical Ly6G + SiglecF + immune cells with neurosupportive potential in olfactory neuroepithelium2020
- Author(s)
  Ogawa Kei、Asano Kenichi、Yotsumoto Satoshi、Yamane Tsuyoshi、Arita Makoto、Hayashi Yoshihiro、Harada Hironori、Makino‐Okamura Chieko、Fukuyama Hidehiro、Kondo Kenji、Yamasoba Tatsuya、Tanaka Masato
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 109 Issue: 3 Pages: 481-496
- DOI
  10.1002/jlb.1hi0620-190rr
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08824, KAKENHI-PROJECT-20K09749, KAKENHI-PROJECT-19K08894, KAKENHI-PROJECT-20H03473
[Journal Article] Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis.2019
- Author(s)
  K. Dodo, E*. Kuboki*, T Shimizu* (*equally contributed first author), R. Imamura, M. Magarisawa, M. Takahashi, T. Tokuhiro, S. Yasumoto, K. Asano, S. Nakao, N. Terayama, T.Suda, M. Tanaka, M. Sodeoka.
- Journal Title
  
  ACS Med Chem Lett.
  
  Volume: 10 Issue: 9 Pages: 1272-1278
- DOI
  10.1021/acsmedchemlett.9b00142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07186, KAKENHI-PROJECT-17H04068, KAKENHI-PROJECT-19K08894
[Journal Article] Endosomal translocation of CpG- oligodeoxynucleotides inhibits DNA-PKcs-dependent IL- 10 production in macrophages2008
- Author(s)
  Yotsumoto, S.
- Journal Title
  
  J. Immunol. 180
  
  Pages: 809-816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790074
[Journal Article] Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophages2008
- Author(s)
  Yotsumoto S
- Journal Title
  
  Journal of Immunology 180(2)
  
  Pages: 809-816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790074
[Journal Article] Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophages.2008
- Author(s)
  Yotsumoto, S., Saegusa, K. and Aramaki, Y.
- Journal Title
  
  J. Immunol 180
  
  Pages: 809-816
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790074
[Presentation] 新しい単球サブセットによるがん転移の促進とその機構2021
- Author(s)
  四元聡志
- Organizer
  第65回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08894
[Presentation] 脂質酸化依存的ネトーシスの誘導機構2021
- Author(s)
  四元聡志
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08894
[Presentation] Myeloperoxidase-dependent lipid peroxidation plays a critical role in neutrophil extracellular trap formation2019
- Author(s)
  Takuto Tokuhiro, Satoshi Yotsumoto, Haruka Sato, Sayuri Yoshikawa, Shunya Takita, Masato Tanaka、
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08894
[Presentation] ネトーシスにおける脂質酸化制御の分子機構2019
- Author(s)
  四元聡志、田中正人
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K08894
[Presentation] Novel interferon(IFN)-based pretransplantaion conditioning in the treatment of congenital metabolic disorder2011
- Author(s)
  佐藤卓,四元聡志,樗木俊聡
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-22790054
[Presentation] 炎症性単球由来樹状細胞は血球貪食依存的にIL-10を生産し、過剰な免疫反応を抑制する2011
- Author(s)
  小内伸幸,大八木秀明,佐藤卓,四元聡志,澤田賢一,樗木俊聡
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790054
[Presentation] CpG-ODN によるIL-10 およびIL-12 生産におけるDNA-PK の関与2008
- Author(s)
  四元聡志
- Organizer
  生体調節シグナルの統合的研究グローバルCOE プログラム第2回若手研究者シンポジウム
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-19790074
[Presentation] Endosomal translocation ofCpG-oligodeoxynucleotides inhibits DNAPKcs- dependent IL-10 production.2008
- Author(s)
  Yotsumoto, S.
- Organizer
  第38 日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790074
[Presentation] Endosomal translocation of CpG- oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production2008
- Author(s)
  Yotsumoto S, Aramaki Y
- Organizer
  第38日本免疫学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-19790074
[Presentation] CpG-ODNによるIL-10およびIL-12生産におけるDNA-PKの関与2008
- Author(s)
  四元聡志
- Organizer
  生体調節シグナルの統合的研究グローバルCOEプログラム第2回若手研究者シンポジウム
- Place of Presentation
  前橋
- Data Source
  KAKENHI-PROJECT-19790074

1. どど孝介 (20415243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. SHIMIZU Tadashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. HARADA Yuka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 有田誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 米田敦子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 原田浩徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yotsumoto Satoshi 四元 聡志

YOTSUMOTO Satoshi 四元 聡志

YOTHUMOTO Satoshi 四元 聡志

Research Projects

Research Products

Co-Researchers

Development of cancer treatments targeting regulatory monocytesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of molecular mechanisms of lipid peroxidation-dependent NET formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of hematopoietic stem cell activation by dendritic cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The design of liposomal carriers for CpG-ODNPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 免疫の事典「IL-15」2011

Author(s)

Total Pages

Publisher

Data Source

[Book] 免疫の事典「IL-15」2011

Author(s)

Publisher

Data Source

[Journal Article] Oxidized Phospholipids and Neutrophil Elastase Coordinately Play Critical Roles in NET Formation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Garcinielliptone G from Garcinia subelliptica Induces Apoptosis in Acute Leukemia Cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunoregulatory Monocyte Subset Promotes Metastasis Associated With Therapeutic Intervention for Primary Tumor2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Frontline Science:?Conversion of neutrophils into atypical Ly6G + SiglecF + immune cells with neurosupportive potential in olfactory neuroepithelium2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of a Water-Soluble Indolylmaleimide Derivative IM-93 Showing Dual Inhibition of Ferroptosis and NETosis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endosomal translocation of CpG- oligodeoxynucleotides inhibits DNA-PKcs-dependent IL- 10 production in macrophages2008

Author(s)

Journal Title

Data Source

[Journal Article] Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophages2008

Author(s)

Journal Title

Data Source

[Journal Article] Endosomal translocation of CpG-oligodeoxynucleotides inhibits DNA-PKcs-dependent IL-10 production in macrophages.2008

Author(s)

Journal Title

Data Source

[Presentation] 新しい単球サブセットによる がん転移の促進とその機構2021

Author(s)

Organizer

Data Source

Yotsumoto Satoshi 四元聡志

YOTSUMOTO Satoshi 四元聡志

YOTHUMOTO Satoshi 四元聡志

[Presentation] 新しい単球サブセットによるがん転移の促進とその機構2021