Takaoka Akinori 高岡晃教

… Alternative Names

TAKAOKA Akinori 高岡晃教

芫岡晃教タカオカアキノリ

Less

Researcher Number	30323611
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 遺伝子病制御研究所, 教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 北海道大学, 遺伝子病制御研究所, 教授 2007 – 2020: Hokkaido University, 遺伝子病制御研究所, 教授 2004 – 2006: The Univ. of Tokyo, Grad. Sch. of Med, Lecturer, 大学院医学系研究科, 講師 2002 – 2005: The University of Tokyo, Graduate School of Medicine, Lecturer, 大学院・医学系研究科, 講師 2001: 東京大学, 大学院・医学系研究科, 助手
Review Section/Research Field	Principal Investigator Biological Sciences / Medium-sized Section 49:Pathology, infection/immunology, and related fields / Biological Sciences / Tumor biology and related fields / Cell biology / Tumor therapeutics / Virology / Immunology / Experimental pathology Except Principal Investigator Biological Sciences / Basic Section 49070:Immunology-related / Eating habits / Integrated Nutrition Science
Keywords	Principal Investigator インターフェロン / ウイルス感染 / 自然免疫 / p53 / シグナル伝達 / 生体防御 / パターン認識受容体 / がん / アポトーシス / 抗ウイルス応答 … More / 樹状細胞 / RIG-I / interferon / 自然免疫応答 / 炎症性サイトカイン / DNA / ウイルス / 核酸 / サイトカイン / ウイルス感染防御 / 病原体認識受容体 / IRFファミリー / 遺伝子欠損マウス / ノンコーディングRNA / Intrinsic immunity / 感染防御 / intrinsic immunity / 自然免疫系 / アダプタータンパク質 / 腫瘍 / シグナル伝達経路 / 細胞内局在 / 新規キナーゼ / 細胞死 / がん細胞 / antiviral defense / innate immunity / Toll-like receptor / apoptosis / dendritic cells / IRF family / 転写因子 / 形質細胞様樹状細胞 / Toll様受容体 / host defense / virus infection / interluekin-6 / tumor suppression / signal transduction / membrane domain / シグナルクロストーク / がん化 / サイトカインシグナル伝達 / 弱いシグナル / IFNAR1 / 癌化抑制 / インターロイキン-6 / 腫瘍抑制 / 細胞膜ドメイン / 抗腫瘍効果 / 放射線照射 / 核酸アジュバント / 自然免疫活性化 / アジュバント / RNAサイレンシング / 転写後調節 / 免疫学 / RNA 転写後調節 / RNA転写後制御 / 抗ウイルス効果 / HCMV / RNA / PARP / 感染 / 分子標的 / 抗体治療 / 脳腫瘍 / DNA修飾 / IRF転写因子 / TLR3 / 適応免疫 / Toll-like receptors / CD8+T細胞 / pathogen-associated molecules / IRF-7 / IRF-3 / 感染免疫 … More Except Principal Investigator 自然免疫 / インターフェロン / Noxa / p53 / RANKL / 食品 / 核酸 / アポトーシス / 発がん抑制 / 樹状細胞 / IRFファミリー / シグナル伝達 / ウイルス / osteoclast / apoptosis / dendritic cells / IRF family / Interferon / IRFファミリー転写因子 / 破骨細胞分化 / シグナルクロストーク / ウイルス感染 / インターフェロン受容体 / Stat1 / TLR3 / RNAKL / 破骨細胞 / 免疫 / 自然免疫賦活化 / 栄養学 / 免疫学 / 口腔粘膜 / 食餌性核酸 / 転写因子 / IRF / がん / Toll様受容体 / Puma Less

lncRNAからエンコードされる新しい抗ウイルスサイトカインの同定と性状解析Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Hokkaido University
Intrinsic immunityに着目した新しい抗ウイルス防御機構の探索Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Hokkaido University
Research on the immune system in uninfected cells that defines the immune response during viral infection
- Principal Investigator
  
  Kameyama Takeshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Kobe University
The molecular mechanism of cancer specific cell death induction via novel innate immune signalingPrincipal Investigator
- Principal Investigator
  
  Takaoka Akinori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Research Field
  
  Tumor biology and related fields
- Research Institution
  Hokkaido University
Activation of innate immune response by DNA from food
- Principal Investigator
  
  HAYAKAWA Sumio
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits
- Research Institution
  Tokyo Medical and Dental University
ヒトサイトメガロウイルス感染により活性化されるパターン認識受容体活性化機構の解析Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
The novel post-transcriptional regulation mechanism of antiviral host defensePrincipal Investigator
- Principal Investigator
  
  Takaoka Akinori
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Virology
- Research Institution
  Hokkaido University
Establishment of local and switchable innate immune activation by novel nucleic acid adjuvantPrincipal Investigator
- Principal Investigator
  
  TAKAOKA Akinori
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Tumor therapeutics
- Research Institution
  Hokkaido University
ウイルスＲＮＡと宿主ＲＮＡによって調節される細胞機能制御のメカニズムPrincipal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
The study of activation of innate immune response by dietary nucleic acids via oral mucosa
- Principal Investigator
  
  KAMEYAMA Takeshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrated Nutrition Science
- Research Institution
  Hokkaido University
ウイルス感染におけるDNAを介する自然免疫応答の解明Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
がんに対するIFNを組み合わせた新しい抗体治療ストラテジーの開発Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
Molecular mechanisms for the detection of microbes and cancer cells in innate immunityPrincipal Investigator
- Principal Investigator
  
  TAKAOKA Akinori
- Project Period (FY)
  2008 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (S)
- Research Field
  
  Immunology
- Research Institution
  Hokkaido University
IRFファミリー転写因子を介した感染防御の分子機構Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Hokkaido University
脳神経系におけるIFNシステムの解析と新規固定型IFNの応用Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Hokkaido University
Informatory expression system connecting cancer and immunity.
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Functional analyses on roles of intetferon-IRF-family transcriptional factorPrincipal Investigator
- Principal Investigator
  
  TAKAOKA Akinori
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tokyo
感染防御系におけるIFN及びIFN調節因子活性化の役割とその分子基盤の解析Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
感染免疫システムにおける多様なシグナル伝達経路の活性化とその意義に関する研究Principal Investigator
- Principal Investigator
  
  高岡晃教
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
感染免疫システムにおける多様なシグナル伝達経路の活性化とその意義に関する研究Principal Investigator
- Principal Investigator
  
  芫岡晃教
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (C)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Studies about novel roles of the membrane domain in signal transduction systemsPrincipal Investigator
- Principal Investigator
  
  TAKAOKA Akinori
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cell biology
- Research Institution
  The University of Tokyo
Gene expression network for tumor suppression
- Principal Investigator
  
  TANIGUCHI Tadatsugu
- Project Period (FY)
  2000 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Book] Characterization of innate immune signalings stimulated by nucleic acid sensors.2014
- Author(s)
  Kameyama, T. Takaoka, A
- Publisher
  Method in Mol. Biology.
- Data Source
  KAKENHI-PROJECT-25253030
[Book] Methods in molecular biology "Characterization of innate immune signalings stimulated by ligands for pattern recognition receptors."2014
- Author(s)
  Takeshi Kameyama, Akinori Takaoka
- Total Pages
  14
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-23617001
[Book] Arthritis Research Methods in Molecular Biology "Characterization of innate immune signalings stimulated by nucleic acid sensors"2014
- Author(s)
  Takeshi Kameyama, Akinori Takaoka
- Total Pages
  14
- Publisher
  Human Press
- Data Source
  KAKENHI-PROJECT-25253030
[Book] Method in Molecular Biology. "Characterization of innate immune signalings stimulated by nucleic acid sensors"2014
- Author(s)
  Takeshi Kameyama, Akinori Takaoka
- Total Pages
  14
- Publisher
  Human Press
- Data Source
  KAKENHI-PROJECT-25640084
[Book] Characterization of innate immune signalings stimulated by nucleic acid sensors.2014
- Author(s)
  Kameyama, T. Takaoka, A
- Publisher
  Methods Mol Biol.
- Data Source
  KAKENHI-PROJECT-25640084
[Book] Method in Mol. Biology. Characterization of innate immune signalings stimulated by nucleic acid sensors2014
- Author(s)
  KAMEYAMA, Takeshi, TAKAOKA, Akinori
- Total Pages
  14
- Publisher
  Humana Press
- Data Source
  KAKENHI-PROJECT-23617001
[Book] 臨床免疫・アレルギー科2012
- Author(s)
  亀山武志,中村亨,高岡晃教
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 分子標的薬,IFN と受容体を介するシグナル経路2012
- Author(s)
  中村亨,高岡晃教
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 分子標的薬,NF-κB シグナル経路と炎症2012
- Author(s)
  山田大翔,高岡晃教
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 感染・炎症・免疫,RIG-Iシグナルの正の制御因子"ZAPS"2011
- Author(s)
  太宰昌佳,高岡晃教
- Publisher
  医薬の門社
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 生体の化学,自然免疫系におけるDNAセンサーとインムラマソーム2011
- Author(s)
  高岡晃教,鈴木絵里加,浦山優輔,木口舞美
- Publisher
  金原一郎記念医学医療振興財団/医学書院
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 疾患モデルの作製と利用-免疫疾患,第3章第3節第2項2011
- Author(s)
  高岡晃教,亀山武志,亀岡章一郎
- Publisher
  IRFファミリー
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 自己炎症疾患の新しい知見総説パターン認識受容体-Pattern recognition receptors-2011
- Author(s)
  高岡晃教,中村亨,林隆也
- Publisher
  Jpn. J. Clin. Immunol
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 自然免疫系における核酸認識機構-核酸センサーRIG-Iと制御因子ZAPS2011
- Author(s)
  高岡晃教,山田大翔,林真寛
- Publisher
  生物の科学遺伝
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 自然免疫系における核酸センサーとサイトカイン誘導経路2010
- Author(s)
  高岡晃教,浦山優輔,鈴木絵里加
- Publisher
  実験医学
- Data Source
  KAKENHI-PROJECT-20679003
[Book] DAI(DNA依存性IRF活性化因子;DNA-dependent activator of interferon-regulatory factors;別名DLM-1/ZBP1)2009
- Author(s)
  高岡晃教
- Total Pages
  237
- Publisher
  「生化学」誌
- Data Source
  KAKENHI-PROJECT-20679003
[Book] IFN,サイトカイン-2 がん治療の分子標的となる IFN-IRF系のシグナル伝達分子2008
- Author(s)
  高岡晃教,佐藤昇志,宮崎忠昭,南山堂
- Publisher
  がんの分子標的治療
- Data Source
  KAKENHI-PROJECT-20679003
[Book] ゲノム医学,自然免疫とウイルス感染2008
- Author(s)
  高岡晃教,大和弘明
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 臨床免疫・アレルギー科,自然免疫のDNA認識機構とそのセンサー分子2008
- Author(s)
  高岡晃教,後藤翔平,樫木芙美
- Publisher
  化学評論社
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 肝疾患Review2008-20092008
- Author(s)
  高岡晃教
- Publisher
  肝炎の基礎DNAウイルスに対する自然免疫
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 自然免疫における核酸センサー分子2008
- Author(s)
  高岡晃教,樫木芙美,後藤翔平,数馬田美香
- Publisher
  「生化学」誌
- Data Source
  KAKENHI-PROJECT-20679003
[Book] がんの分子標的治療2008
- Author(s)
  高岡晃教,佐藤昇志,宮崎忠昭
- Publisher
  がん治療の分子標的となるIFN-IRF系のシグナル伝達分子
- Data Source
  KAKENHI-PROJECT-20679003
[Book] 分子細胞治療,用語解説より「DAI」2008
- Author(s)
  白鳥聡一,高岡晃教
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Novel rapid method for identifying and quantifying pathogenic bacteria within four hours of blood collection.2024
- Author(s)
  Miyakoshi A, Niimi H, Ueno T, Wakasugi M, Higashi Y, Miyajima Y, Mori M, Tabata H, Minami H, Takaoka A, Hayashi A, Yamamoto Y, Kitajima I.
- Journal Title
  
  Sci Rep
  
  Volume: 14 Issue: 1 Pages: 1199-1199
- DOI
  10.1038/s41598-023-50864-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00447
[Journal Article] Augmented interferon regulatory factor 7 axis in whole tumor cell vaccines prevents tumor recurrence by inducing interferon gamma-secreting B cells2023
- Author(s)
  Kajihara Nabeel、Tanaka Yoshino、Takeuchi Riko、Kobayashi Takuto、Tanji Masafumi、Ataka Tsukasa、Nakano Shiho、Yamada Taisho、Takaoka Akinori、Hasegawa Yoshinori、Seino Ken-Ichiro、Wada Haruka
- Journal Title
  
  OncoImmunology
  
  Volume: 12 Issue: 1 Pages: 2213132-2213132
- DOI
  10.1080/2162402x.2023.2213132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07049, KAKENHI-PROJECT-22K19449, KAKENHI-PROJECT-22KJ0121, KAKENHI-PROJECT-22H00447
[Journal Article] Innate immune recognition against SARS-CoV-2.2023
- Author(s)
  Taisho Yamada、Akinori Takaoka
- Journal Title
  
  Inflamm Regen.
  
  Volume: 43 Pages: 1-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00447
[Journal Article] Loss of PARP7 Increases Type I Interferon Signaling in EO771 Breast Cancer Cells and Prevents Mammary Tumor Growth by Increasing Antitumor Immunity.2023
- Author(s)
  Rasmussen M, Alvik K, Kannen V, Olafsen NE, Erlingsson LAM, Grimaldi G, Takaoka A, Grant DM, Matthews J.
- Journal Title
  
  Cancers (Basel).
  
  Volume: 15 Issue: 14 Pages: 3689-3689
- DOI
  10.3390/cancers15143689
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22H00447
[Journal Article] Essential role of Rnd1 in innate immunity during viral and bacterial infections2022
- Author(s)
  Kumar Akhilesh、Mishra Shalabh、Kumar Ashish、Raut Ashwin Ashok、Sato Seiichi、Takaoka Akinori、Kumar Himanshu
- Journal Title
  
  Cell Death & Disease
  
  Volume: 13 Issue: 6 Pages: 520-520
- DOI
  10.1038/s41419-022-04954-y
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22H00447
[Journal Article] Regulation of an adaptor protein STING by Hsp90β to enhance innate immune responses against microbial infections2020
- Author(s)
  Seiichi Sato, Kai Li, Nozomi Sakurai, Mei Hashizume, Sunanda Baidya, Hirotaka Nonaka, Koki Noguchi, Kozo Ishikawa, Chikashi Obuse, Akinori Takaoka
- Journal Title
  
  Cellular Immunology
  
  Volume: 356 Pages: 104188-104188
- DOI
  10.1016/j.cellimm.2020.104188
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05532, KAKENHI-PROJECT-19H03156, KAKENHI-PROJECT-18K07162, KAKENHI-PROJECT-18K07191
[Journal Article] BinCARD2 as a positive regulator of interferon response in innate immunity2019
- Author(s)
  Suzuki Hiraku、Kameyama Takeshi、Takaoka Akinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 511 Issue: 2 Pages: 287-293
- DOI
  10.1016/j.bbrc.2019.02.029
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07162
[Journal Article] Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathways.2017
- Author(s)
  Kumari P, Saha I, Narayanan A, Narayanan S, Takaoka A, Kumar NS, Tailor P, Kumar H.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 8 Issue: 10 Pages: e3078-e3078
- DOI
  10.1038/cddis.2017.461
- Data Source
  KAKENHI-PROJECT-25253030
[Journal Article] TRIM25 Enhances the Antiviral Action of Zinc-Finger Antiviral Protein (ZAP).2017
- Author(s)
  YLi MM, Lau Z, Cheung P, Aguilar EG, Schneider WM, Bozzacco L, Molina H, Buehler E, Takaoka A, Rice CM, Felsenfeld DP, MacDonald MR
- Journal Title
  
  PLoS Pathog
  
  Volume: 13 Issue: 1 Pages: e1006145-e1006145
- DOI
  10.1371/journal.ppat.1006145
- Open Access
- Data Source
  KAKENHI-PROJECT-25253030
[Journal Article] Helicobacter pylori induces IL-1β protein through the inflammasome activation in differentiated macrophagic cells 2016
- Author(s)
 Kameoka, S.
- Journal Title
 
 Biomed. Res.
 
 Volume: 37 Issue: 1 Pages: 21-27
- DOI
 10.2220/biomedres.37.21
- NAID
 130005128374
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-ORGANIZER-22114001, KAKENHI-PROJECT-25250016, KAKENHI-PROJECT-25253030, KAKENHI-PROJECT-16H06373, KAKENHI-PROJECT-16K15273
[Journal Article] Constitutive aryl hydrocarbon receptor signaling constrains type I interferon-mediated antiviral innate defense.2016
- Author(s)
  Yamada T, Horimoto H, Kameyama T, Hayakawa S, Yamato H, Dazai M, Takada A, Kida H, Bott D, Zhou AC, Hutin D, Watts TH, Asaka M, Matthews, Takaoka A
- Journal Title
  
  Nat Immunol.
  
  Volume: 印刷中 Issue: 6 Pages: 687-694
- DOI
  10.1038/ni.3422
- NAID
  120005849912
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25713032, KAKENHI-PUBLICLY-15H01249, KAKENHI-PROJECT-25253030, KAKENHI-PROJECT-24390110
[Journal Article] The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus2015
- Author(s)
  Sato S, Li K, Kameyama T, Hayashi T, Ishida Y, Murakami S, Watanabe T, Iijima S, Sakurai Y, Watashi K, Tsutsumi S, Sato Y, Akita H, Wakita T, Rice CM, Harashima H, Kohara M, Tanaka Y, Takaoka A
- Journal Title
  
  Immunity
  
  Volume: 42 Issue: 1 Pages: 123-132
- DOI
  10.1016/j.immuni.2014.12.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25253030, KAKENHI-PROJECT-25870015, KAKENHI-PROJECT-25893001, KAKENHI-PUBLICLY-26102747, KAKENHI-PROJECT-26460565, KAKENHI-PROJECT-26893001
[Journal Article] Superoxide Dismutase 1 Protects Hepatocytes from Type I Interferon-Driven Oxidative Damage.2015
- Author(s)
  Bhattacharya A, Hegazy AN, Deigendesch N, Kosack L, Cupovic J, Kandasamy RK, Hildebrandt A, Merkler D, Kühl AA, Vilagos B, Schliehe C, Panse I, Khamina K, Baazim H, Arnold I, Flatz L, Xu HC, Lang PA, Aderem A, Takaoka A, Superti-Furga G, Colinge J, Ludewig B, Löhning M, Bergthaler A.
- Journal Title
  
  Immunity
  
  Volume: 43 Issue: 5 Pages: 974-986
- DOI
  10.1016/j.immuni.2015.10.013
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253030
[Journal Article] The microRNA miR-485 targets host and influenza virus transcripts to regulate antiviral immunity and restrict viral replication.2015
- Author(s)
  Ingle H, Kumar S, Raut AA, Mishra A, Kulkarni DD, Kameyama T, Takaoka A, Akira S, Kumar H.
- Journal Title
  
  Science Signaling
  
  Volume: 8 Issue: 406
- DOI
  10.1126/scisignal.aab3183
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25253030
[Journal Article] Targeted induction of interferon- λ in humanized chimeric mouse liver abrogates hepatotropic virus infection.2013
- Author(s)
  Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, MizokamiM, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M
- Journal Title
  
  PLoS One
  
  Volume: 8(3) Pages: 59611-59611
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Targeted Induction of Interferon-λ in Humanized Chimeric Mouse Liver Abrogates Hepatotropic Virus Infection.2013
- Author(s)
  Nakagawa S, Hirata Y, Kameyama T, Tokunaga Y, Nishito Y, Hirabayashi K, Yano J, Ochiya T, Tateno C, Tanaka Y, Mizokami M, Tsukiyama-Kohara K, Inoue K, Yoshiba M, Takaoka A, Kohara M.
- Journal Title
  
  PLoS One.
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1.2012
- Author(s)
  Chiba S, Baghdadi M, Akiba H, Yoshiyama H, Kinoshita I, Dosaka-Akita H, Fujioka Y, Ohba Y, Gorman JV, Colgan JD, Hirashima M, Uede T, Takaoka A, Yagita H, Jinushi M.
- Journal Title
  
  Nat Immunol.
  
  Volume: 13 Pages: 832-842
- NAID
  120005228241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB12012
- Author(s)
  Chiba S, Baghdadi M, Akiba H, Yoshiyama H, Kinoshita I, Dosaka-Akita H, Fujioka Y, Ohba Y, Gorman JV, Colgan JD, Hirashima M, Uede T, Takaoka, A, Yagita H, Jinushi M
- Journal Title
  
  Nat Immunol
  
  Volume: 13(9) Pages: 832-842
- NAID
  120005228241
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells2011
- Author(s)
  Jinushi, M., Chiba, S., Yoshiyama, H., Masutomi, K., Kinoshita, I., Dosaka-Akita, H., Yagita, H., Takaoka, A., Tahara, H
- Journal Title
  
  Proc. Natl. Acad. Sci. U S A
  
  Volume: 108 Pages: 12425-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] IRF3 regulates cardiac fibrosis but not hypertrophy in mice during angiotensin II-induced hypertension2011
- Author(s)
  Tsushima K, Osawa T, Yanai H, Nakajima A, Takaoka A, et al.
- Journal Title
  
  FASEB J.
  
  Volume: 25 Pages: 1531-1543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses2011
- Author(s)
  Hayakawa, S., Shiratori, S., Yamato, H., Kameyama, T., Kitatsuji, C., Kashigi, F., Goto, S., Kameoka, S., Fujikura, D., Yamada, T., Mizutani, T., Kazumata, M., Sato, M., Tanaka, J., Asaka, M., Ohba, Y., Miyazaki, T., Imamura, M., and Takaoka, A
- Journal Title
  
  Nat. Immunol
  
  Volume: 12 Pages: 37-44
- NAID
  120003118156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Interferon-α/ss and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011
- Author(s)
  Sasaki, S., Ishida, T., Toyota, M., Ota, A., Suzuki, H., Takaoka, A., Yasui, H., Yamamoto, H., Takagi, H., Maeda, M., Seito, T., Tsujisaki, M., Shinomura, Y., Imai, K
- Journal Title
  
  PLoS One
  
  Volume: 6 Pages: 19618-19618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Interferon-α/β and anti-fibroblast growth factor receptor 1 monoclonal antibody suppress hepatic cancer cells in vitro and in vivo2011
- Author(s)
  Sasaki S, Ishida T, Toyota M, Ota A, Suzuki H, Takaoka A, et al.
- Journal Title
  
  PLoS One.
  
  Volume: 6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] ATM-mediated DNA damage signals mediate immune escape through integrin αvβ3-dependent mechanisms2011
- Author(s)
  Jinushi, M., Chiba, S., Baghdadi, M., Kinoshita, I., Dosaka-Akita, H., Ito, K., Yoshiyama, H., Yagita, H., Uede, T., Takaoka, A
- Journal Title
  
  Cancer Res
  
  Volume: 72 Pages: 56-65
- NAID
  120005090590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] IRF3 regulates cardiac fibrosis butnot hypertrophy in mice during angiotensinII-induced hypertension2011
- Author(s)
  Tsushima, K., Osawa, T., Yanai, H., Nakajima, A., Takaoka, A., Manabe, I., Ohba, Y., Imai, Y., Taniguchi, T., Nagai, R
- Journal Title
  
  FASEB J
  
  Volume: 25 Pages: 1531-1543
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] ATM-mediated DNA damage signals mediate immune escape through integrin ανβ3-dependent mechanisms2011
- Author(s)
  Jinushi M, Chiba S, Baghdadi M, Kinoshita I. Dosaka-Akit H, Ito K, Yoshiyama H, Yagita H, Uode T, Takaoka A.
- Journal Title
  
  Cancer Res.
  
  Volume: 72 Pages: 56-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] ZAPS is a potent stimulator of RIG-I-mediated signaling during antiviral response2011
- Author(s)
  Hayakawa, S., Shiratori, S., Yamato, H., Kameyama, T., Kitatsuji, C., Kashigi, F., Goto, S., Kameoka, S., Fujikura, D., Yamada, T., Mizutani, T., Kazumata, M., Sato, M., Tanaka, J., Imamura, M., Asaka, M., Ohba, Y., Miyazaki, T., Takaoka, A.
- Journal Title
  
  Nat. Immunol 12
  
  Pages: 37-44
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Critical role for constitutive type I interferon signaling in the prevention of cellular transformation2009
- Author(s)
  Chen, H.M., Tanaka, N., Mitani, Y., Oda,E., Nozawa, H., Chen, J.Z., Yanai, H., Negishi, H., Choi, M.K., Iwasaki, T., Yamamoto, H., Taniguchi, T., and Takaoka, A.
- Journal Title
  
  Cancer Sci
  
  Volume: 100 Pages: 449-456
- NAID
  10025143268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Critical role for constitutive type I interferon signaling in the prevention of cellular transformation.2009
- Author(s)
  Chen HM, Tanaka N, Mitani Y, Oda E, Nozawa H, Chen JZ, Yanai H, Negishi H, Choi MK, Iwasaki T, Yamamoto H, Taniguchi T, Takaoka A.
- Journal Title
  
  Cancer Sci. Vol.100
  
  Pages: 449-456
- NAID
  10025143268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Critical role for constitutive type I interferon signaling in the prevention of cellular transformation2009
- Author(s)
  Chen, H.M., Tanaka, N., Mitani, Y., Oda, E., Nozawa, H., Chen, J.Z., Yanai, H., Negishi, H., Choi, M.K., Iwasaki, T., Yamamoto, H., Taniguchi, T., Takaoka, A.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 449-456
- NAID
  10025143268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Interferon regulatory factor family of transcription factors and regulation of oncogenesis.2008
- Author(s)
  Takaoka A, Tamura T, Taniguchi T.
- Journal Title
  
  Cancer Sci. Vol.99
  
  Pages: 467-478
- NAID
  10024003254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules.2008
- Author(s)
  Wang Z, Choi MK, Ban T, Yanai H, Negishi H, Lu Y, Tamura T, Takaoka A, Nishikura K, Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.105
  
  Pages: 5477-5482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules2008
- Author(s)
  Wang, Z., Choi, M.K., Ban, T., Yanai, H., Negishi, H., Lu, Y., Tamura, T., Takaoka, A., Nishikura, K., Taniguchi, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 105
  
  Pages: 5477-5482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Cytosolic DNA recognition for triggering innate immune responses2008
- Author(s)
  Takaoka, A., Taniguchi, T.
- Journal Title
  
  Adv. Drug Deliv. Rev. 60
  
  Pages: 847-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] IRF family of transcription factors and regulation of oncogenesis2008
- Author(s)
  Takaoka, A., Tamura, T., Taniguchi, T.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 467-678
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20679003
[Journal Article] Interferon regulatory factor family of transcription-factors and regulation of oncogenesis.2008
- Author(s)
  Takaoka A., et. al.
- Journal Title
  
  Cancer Science 99
  
  Pages: 467-478
- NAID
  10024003254
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Cytosolic DNA recognition for triggering innate immune responses2008
- Author(s)
  Takaoka, A., et al.
- Journal Title
  
  Advanced Drug Delivery Reviews 60
  
  Pages: 847-857
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390109
[Journal Article] IRF family of transcription factors and regulation of oncogenesis.2008
- Author(s)
  Takaoka, A., et. al.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 467-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041021
[Journal Article] IRF family of transcription factors and regulation of oncogenesis.2008
- Author(s)
  Takaoka, A., et. al.
- Journal Title
  
  Cancer Sci. 99
  
  Pages: 467-478
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390109
[Journal Article] DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.2007
- Author(s)
  Takaoka, A., et. al.
- Journal Title
  
  Nature 448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041021
[Journal Article] DAI(DLM-1/ZBP1)is a cytosolic DNA sensor and an activator of innate immune response.2007
- Author(s)
  Takaoka, A., et. al.
- Journal Title
  
  Nature 448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390109
[Journal Article] DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response.2007
- Author(s)
  Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, Lu Y, Miyagishi M, Kodama T, Honda K, Ohba Y, Taniguchi T.
- Journal Title
  
  Nature Vol.448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Cytosolic DNA recognition for triggering innate immune responses.2007
- Author(s)
  Takaoka, A., et. al.
- Journal Title
  
  Adv. Drug Deliv. Rev. (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041021
[Journal Article] Pole of IFN regulatory factor 5 transcription factor in anitiviral immunity and tumor suppression.2007
- Author(s)
  Yanai H, Chen HM, Inuzaka T, Koado S, Mak TW, Takaoka A, Honda K, Taniguchi T.
- Journal Title
  
  Proc Natl Acad Sci U S A. 104
  
  Pages: 3402-3407
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai H., Chen H., Inuzuka T., Kondo S., Mak WT., Takaoka A., Honda K. Taniguchi T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.104
  
  Pages: 3402-3407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H., Inuzuka, T., Kondo, S., Mak, W.T., Takaoka.A., Honda, K., Taniguchi, T.
- Journal Title
  
  PNAS 104
  
  Pages: 3402-3407
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Role of IFN regulatory factor 5 transcription factor in antiviral immunity and tumor suppression.2007
- Author(s)
  Yanai, H., Chen, H.M., Inuzuka, T., Kondo, S., Mak, Takaoka, A., Honda, K., Taniguchi, T.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 104
  
  Pages: 3402-3407
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immuneresponse.2007
- Author(s)
  Takaoka A, et. al.
- Journal Title
  
  Nature 448
  
  Pages: 501-505
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Interferon signaling network in innate defense.2006
- Author(s)
  Takaoka, A., Yanai, H.
- Journal Title
  
  Cellular Microbiology (印刷中)
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Differential contribution of Puma and Noxa in dual regulation of p53-dependent apoptotic pathways.2006
- Author(s)
  Shibue T, Suzuki S, Okamoto H, Yoshida H, Ohba Y, Takaoka A, Taniguchi T.
- Journal Title
  
  EMBO J. Vol.25
  
  Pages: 4952-4962
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Differential contribution of Puma and Noxa in dual regulation of p53-dependent apoptotic pathways.2006
- Author(s)
  Shibue, T., Suzuki, S., Okamoto, H., Yoshida, H., Ohba, Y., Takaoka, A., Taniguchi, T.
- Journal Title
  
  EMBO J. 25
  
  Pages: 4952-4962
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature Vol. 434, No 7030
  
  Pages: 243-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.2005
- Author(s)
  Honda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi H, Ohba Y, Yanai H, Takaoka A, Honma K, Yui K, Matsuyama T, Taniguchi T, Honda K.
- Journal Title
  
  Proc Natl Acad Sci U S A. 102
  
  Pages: 15989-15994
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses2005
- Author(s)
  Hnonda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors2005
- Author(s)
  Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.M., Taniguchi T.
- Journal Title
  
  Nature 434
  
  Pages: 243-249
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K, Yanai H, Negishi H, Asagiri M, Sato M, Mizutani T, Shimada N, Ohba Y, Takaoka A, Yoshida N, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signaling for robust type I interferon induction.2005
- Author(s)
  Honda K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature Vol 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors2005
- Author(s)
  Takaoka A., Yanai H., Kondo S., Duncan G., Negishi H., Mizutani T., Kano S., Honda K., Ohba Y., Mak T.M., Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene nduction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 243-249
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., Taniguchi T.
- Journal Title
  
  Nature Vol 434, No. 7034
  
  Pages: 772-777
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Type I interferon system and IRF family of transcription factors in host defense regulation2005
- Author(s)
  Taniguchi, T., Takaoka, A.
- Journal Title
  
  Proc.Jpn.Acad., Ser.B Vol.81
  
  Pages: 1-13
- NAID
  130000093822
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like receptor signaling by IRF-42005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. Vol.102
  
  Pages: 15989-15994
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction2005
- Author(s)
  Hnnda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka.A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y, Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature 434・7030
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, Kano S, Honda K, Ohba Y, Mak TM, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 243-249
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like receptor signaling by IRF-4.Proc.Natl.Acad.Sci.USA.2005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, K., Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA. Vol.102
  
  Pages: 15989-15994
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Regulation of the type I IFN induction : a current view2005
- Author(s)
  Honda, K., Yanai, H., Takaoka, A., Taniguchi, T.
- Journal Title
  
  Int.Immunol Vol.17
  
  Pages: 367-1378
- NAID
  10020560939
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi, H., Ohba, Y., Yanai, H., Takaoka, A., Honma, Yui, K., Matsuyama, T., Taniguchi, T., Honda, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA 120
  
  Pages: 15989-15994
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Type I interferon system and IRF family of transcription factors in host defense regulation.2005
- Author(s)
  Taniguchi, T., Takaoka, A.
- Journal Title
  
  Proc.Jpn.Acad.Ser.B vol.81, no.1
  
  Pages: 1-13
- NAID
  130000093822
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Type I interferon system and IRF family of transcription factors in host defense regulation.2005
- Author(s)
  Taniguchi, T., Takaoka, A.
- Journal Title
  
  Proc.Jpn.Acad., Ser.B Vol.81
  
  Pages: 1-13
- NAID
  130000093822
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon induction.2005
- Author(s)
  Honda K., Ohba, Y., Yanai, H., Negishi H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T
- Journal Title
  
  Nature 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 772-777
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Spatiotemporal regulation of MmyD88-IRF-7 signalling for robust type I interferon induction.2005
- Author(s)
  Honda K, Ohba Y, Yanai H, Negishi H, Mizutani T, Takaoka A, Taya C, Taniguchi T.
- Journal Title
  
  Nature Vol.434
  
  Pages: 1035-1040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Regulation of the type I IFN induction: a current view.2005
- Author(s)
  Honda K, Yanai H, Takaoka A, Taniguchi T.
- Journal Title
  
  Int. Immunol. Vol.17
  
  Pages: 1367-1378
- NAID
  10020560939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type I nterferon induction.2005
- Author(s)
  Honda, K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya, C., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] IRF-7 is the masterregulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda K., Yanai H., Negishi H., Asagiri M., Sato M., Mizutani T., Shimada N., Ohba Y., Takaoka A., Yoshida N., Taniguchi T.
- Journal Title
  
  Nature Vol 434, No. 7034
  
  Pages: 772-777
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] IRF-7 is the master regulator of type-I interferon-dependent immune responses.2005
- Author(s)
  Honda, K., Yanai, H., Negishi, H., Asagiri, M., Sato, M., Mizutani, T., Shimada, N., Ohba, Y., Takaoka, A., Yoshida, N., Taniguchi, T.
- Journal Title
  
  Nature 434
  
  Pages: 727-777
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Negative regulation of Toll-like-receptor signaling by IRF-4.2005
- Author(s)
  Negishi H, Ohba Y, Yanai H, Takaoka A, Honma K, Yui K, Matsuyama T, Taniguchi T, Honda K.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA Vol.102
  
  Pages: 15989-15994
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors.2005
- Author(s)
  Takaoka, A., Yanai, H., Kondo, S., Duncan, G., Negishi, H., Mizutani, T., Kano, S., Honda, K., Ohba, Y., Mak, T.M., Tanigichi, T.
- Journal Title
  
  Nature (in press)
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Type I interferon system and IRF family of transcription factors in host defense regulation.2005
- Author(s)
  Taniguchi T, Takaoka A.
- Journal Title
  
  Proc. Jpn. Acad. Vol.81
  
  Pages: 1-13
- NAID
  130000093822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17012005
[Journal Article] Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type I interferon induction2005
- Author(s)
  Honda K., Ohba, Y., Yanai, H., Negishi, H., Mizutani, T., Takaoka, A., Taya C., Taniguchi, T.
- Journal Title
  
  Nature Vol 434
  
  Pages: 1035-1040
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.2004
- Author(s)
  Honda, K., Yanai, H., Mizutani, T., Negishi, H., Shimada, N., Suzuki, N., Ohba, Y., Takaoka, A., Wen-Chen Yeh, Taniguchi, T
- Journal Title
  
  Proc.Natl.Acad.Sci.USA vol.101, no.43
  
  Pages: 15416-15421
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Role of a transductional-transcriptional processor complex involving MyD88 and IRF-7 in Toll-like receptor signaling.2004
- Author(s)
  Honda, K., Yanai, H, Mizutani, T, Negishi, H., Shimada, N, Suzuki, N, Obba, Y, Takaoka.A., Wen-Chen Yeh, Taniguchi, T.
- Journal Title
  
  Proc.Natl.Acad.Sci.USA 101・43
  
  Pages: 15416-15421
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] New aspects of IFN-α/β signalling in immunity, oncogenesis and bone metabolism.2004
- Author(s)
  Takaoka, A., Taniguchi, T.
- Journal Title
  
  Gann Monograph on Cancer Research no.52
  
  Pages: 141-156
- NAID
  10012730381
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Integral role of Noxa in p53-mediated apoptotic response.2003
- Author(s)
  Shibue, T., Takeda, K., Oda, E., Tanaka, H., Murasawa, H., Takaoka, A., Morishita, Y., Akira, S., Taniguchi, T., Tanaka, N.
- Journal Title
  
  Genes. Dev. 17
  
  Pages: 2233-2238
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Integration of IFN-α/β sinalling to p53 responses in tumour suppression and anitiviral defense.2003
- Author(s)
  Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi H., Kikuchi, H., Sasaki, S., Imai, K., Shibue, T., Honda, K., Taniguchi, T.
- Journal Title
  
  Nature 424
  
  Pages: 516-526
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] Integration of IFN-a/f3 signalling to p53 responses in tumour suppression and antiviral defense.2003
- Author(s)
  Takaoka, A., Hayakawa, S., Yanai, H., Stoiber, D., Negishi, H., Kikuchi, H., Sasaki, S., Imai, K., Shibue, T., Honda, K., Taniguchi, T.
- Journal Title
  
  Nature 424
  
  Pages: 516-526
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017220
[Journal Article] The interferon-alpha/beta system in antiviral responses : a multimodal machinery of gene regulation by the IRF family of transcription factors2002
- Author(s)
  Taniguchi T, Takaoka A.
- Journal Title
  
  Current Opinion in Immunology 314巻・1号
  
  Pages: 111-116
- Data Source
  KAKENHI-PROJECT-13680772
[Journal Article] The interferon-alpha/beta system in antiviral responses : a multimodal machinery of gene regulation by the IRF family of transcription factors.2002
- Author(s)
  Taniguchi T, Takaoka A
- Journal Title
  
  Current Opinion in Immunology 14巻・1号
  
  Pages: 111-116
- Data Source
  KAKENHI-PROJECT-13680772
[Journal Article] IRF family of transcription factors as regulators of host defense.2001
- Author(s)
  Taniguchi T, Ogasawara K, Takaoka A, Tanaka N
- Journal Title
  
  Annual Review of Immunology 19巻
  
  Pages: 623-655
- Data Source
  KAKENHI-PROJECT-13680772
[Journal Article] Constitutive IFN-alpha/beta signal for efficient IFN-alpha/beta gene induction by virus.2001
- Author(s)
  Hata N, Sato M, Takaoka A, Asagiri M, 他2名
- Journal Title
  
  Biochemical and Biophysical Research Communications 285巻2号
  
  Pages: 518-525
- Data Source
  KAKENHI-PROJECT-13680772
[Journal Article] Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling.2001
- Author(s)
  Mitani Y, Takaoka A, Kim SH, 他4名
- Journal Title
  
  Genes to Cells 6巻・7号
  
  Pages: 631-640
- Data Source
  KAKENHI-PROJECT-13680772
[Journal Article] A weak signal for strong responses : interferon-alpha/beta revisited.2001
- Author(s)
  Taniguchi T, Takaoka A
- Journal Title
  
  Nature Reviews Molecular Cell Biology 2巻
  
  Pages: 378-386
- Data Source
  KAKENHI-PROJECT-13680772
[Journal Article] T-cell-mediated regulation of osteoclastogenesis by signaling cross-talk between RANKL and IFN-γ.2000
- Author(s)
  Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., Nakamura, k., Taniguchi, T.
- Journal Title
  
  Nature 408
  
  Pages: 600-605
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Crosstalk between interferon-γ and-α/β signaling components at caveolar membrane domain.2000
- Author(s)
  Takaoka, A., Mitani, Y., Suemori, H., Sato, S., Yokochi, T., Noguchi, S., Tanaka, N., Taniguchi, T.
- Journal Title
  
  Science 288
  
  Pages: 2357-2360
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] Crosstalk between interferon-γand-α/βsignaling components at caveolar membrane domain.2000
- Author(s)
  Takaoka.A., Mitani, Y., Suemori, H., Sato, S., Yokochi, T., Noguchi, S., Tanaka, N., Taniguchi, T.
- Journal Title
  
  Science 288
  
  Pages: 2357-2360
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Journal Article] T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ.2000
- Author(s)
  Takayanagi, H., Ogasawara, K., Hida, S., Chiba, T., Murata, S., Sato, K., Takaoka, A., Yokochi, T., Oda, H., Tanaka, K., Nakamura, k., Taniguchi, T.
- Journal Title
  
  Nature 408
  
  Pages: 600-605
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-12219204
[Presentation] 癌細胞におけるIL-32の直接的な作用の検討2018
- Author(s)
  郷俊寛、亀山武志、高岡晃教
- Organizer
  第22回日本がん免疫学会
- Data Source
  KAKENHI-PROJECT-18K07162
[Presentation] 植物由来のDNAによる自然免疫応答活性化の解析2014
- Author(s)
  戸田遙香, 早川清雄, 亀山武志, 高岡晃教
- Organizer
  日本インターフェロン・サイトカイン学会
- Place of Presentation
  札幌(フラテホール)
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-23617001
[Presentation] 植物由来のDNAによる自然免疫応答活性化の解析2014
- Author(s)
  戸田遥香, 早川清雄, 亀山武志, 高岡晃教
- Organizer
  日本インターフェロン・サイトカイン学会
- Place of Presentation
  札幌（フラテホール）
- Data Source
  KAKENHI-PROJECT-23617001
[Presentation] ZAPS acts as a key factor of RIG-I-mediated activation of innate immune responses during influenza virus2013
- Author(s)
  Akinori Takaoka
- Organizer
  2nd International Conference on Clinincal & Cellular Immunology
- Place of Presentation
  Hampton Inn Tropicana, Las Vegas USA
- Data Source
  KAKENHI-PROJECT-25253030
[Presentation] Zaps as a booster of innate immune signaaling for antviral defense against influenza virus infection2012
- Author(s)
  Takaoka, A
- Organizer
  4th INTERNATIONAL CONFERENCE ON DRUG DISCOVERY & THERAPY
- Place of Presentation
  Dubai Mens College (ドバイ)
- Year and Date
  2012-02-12
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] ZAPS functions as an antiviral regulator in innate immunity2012
- Author(s)
  Takaoka, A
- Organizer
  Istanbul International Immunology Forum
- Place of Presentation
  CROWNE PLAZA ISTANBUL-OLD CITY HOTEL (イスタンブール)
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] ZAPS potentiates RIG-I signaling to drive type IFN production for antiviral response2012
- Author(s)
  Takaoka, A
- Organizer
  ICAR2012
- Place of Presentation
  Universidade de Lisboa(ポルトガル)
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Nucleic acid sensors for detecting viral infection2012
- Author(s)
  Takaoka, A
- Organizer
  IEIIS2012Homeostatic Inflammation Symposium
- Place of Presentation
  学術総合センター
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Helicobacter pylori pathogenic facter CagA dependent induction of interleukin-1 ss from macrophages2012
- Author(s)
  高岡晃教
- Organizer
  日本免疫学会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Roles of ZAPS as an antiviral regulator in innate immunity2011
- Author(s)
  Takaoka, A
- Organizer
  2nd CSI/JSI/KAI Joint Symposium onImmunology
- Place of Presentation
  千里阪急ホテル
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Identification of a novel regulator of the innate signaling activated by virus-derived nucleic acids2010
- Author(s)
  高岡晃教
- Organizer
  2010 annual meeting of the french society for immunology
- Place of Presentation
  Palais du Pharo(フランス)(招待講演)
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PUBLICLY-21022001
[Presentation] Innate immune signaling and cancer2010
- Author(s)
  高岡晃教
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ホテルロイトン札幌
- Year and Date
  2010-09-21
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] A Novel Regulator of the Innate Signaling Activated by Cytoplasmic Nucleic Acids2010
- Author(s)
  高岡晃教
- Organizer
  BIT's 1st World Congress of Virus and Infections-2010
- Place of Presentation
  Busan Exhibition & Convention Center(韓国) 招待講演
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Regulation of cytosolic nucleic acid-activated innate responses by the IFN-inducible protein SCI22010
- Author(s)
  Takaoka, A
- Organizer
  The14th International Congress of Immunology
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-08-25
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Identification of a novel regulator of the innate signaling activated by virus-derived nucleic acids2010
- Author(s)
  Takaoka, A.
- Organizer
  Annual Meeting of the French Society for Immunology 2010
- Place of Presentation
  Marseilles, France
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] A Novel Regulator of the Innate Signaling Activated by Cytoplasmic Nucleic Acids2010
- Author(s)
  Takaoka, A.
- Organizer
  BIT's 1st World Congress Of Virus and Infections 2010
- Place of Presentation
  Busan, Korea
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] A Novel Regulator of the Innate Signaling Activated by Cytoplasmic Nucleic Acids2010
- Author(s)
  高岡晃教
- Organizer
  BITs 1st World Congress Of Virus and Infections-2010
- Place of Presentation
  Busan Exhibition & Convention Center(韓国)(招待講演)
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PUBLICLY-21022001
[Presentation] A Novel Regulator of the Innate Signaling Activated by Cytoplasmic Nucleic Acids2010
- Author(s)
  Takaoka, A
- Organizer
  BIT's 1st World Congress Of Virus and Infections-2010
- Place of Presentation
  Busan Exhibition & Convention Center (韓国)
- Year and Date
  2010-07-31
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Identification of a novel regulator of the innate signaling activated by virus-derived nucleic acids2010
- Author(s)
  高岡晃教
- Organizer
  2010 annual meeting of the french society for immunology
- Place of Presentation
  palais du Pharo(フランス) 招待講演
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Identification of a novel regulator of the innate signalingactivated by virus-derived nucleic acids2010
- Author(s)
  Takaoka, A
- Organizer
  2010 annual meeting of the french society for immunology
- Place of Presentation
  Palais du Pharo (フランス)
- Year and Date
  2010-11-25
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] 自然免疫におけるIFN応答の新たな制御メカニズム2009
- Author(s)
  高岡晃教
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] SCI2を介した自然免疫応答制御2009
- Author(s)
  高岡晃教
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PUBLICLY-21022001
[Presentation] SCI2を介した自然免疫応答制御2009
- Author(s)
  高岡晃教
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] SCI2を介した自然免疫応答制御2009
- Author(s)
  高岡晃教
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] 核酸を介する自然免疫活性化機構の解析2009
- Author(s)
  高岡晃教
- Organizer
  第39回日本免疫学会総会・学術集会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] SCI2を介した自然免疫応答制御2009
- Author(s)
  高岡晃教,早川清雄
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] SCI2を介した自然免疫応答制御2009
- Author(s)
  高岡晃教
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸ポートアイランド(神戸)
- Year and Date
  2009-10-24
- Data Source
  KAKENHI-PROJECT-20015002
[Presentation] DNA-mediated activation of innate of immune responses; itspossible involvement in turmor immunity2008
- Author(s)
  Takaoka, A
- Organizer
  BIT's 1st Annual World Vaccine Congress2008
- Place of Presentation
  Foshan Sanshui GardenHotel (中国)
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] DNA-mediated activation of innate immune responses ; its possible involvement in tumor immunity2008
- Author(s)
  高岡晃教
- Organizer
  BIT 1st World Congress of Vaccine-2008
- Place of Presentation
  中国, 佛山, Foshan Sanshui Garden Hotel
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19041021
[Presentation] DNA sensing mechanism for the activation of innate immune responses2008
- Author(s)
  高岡晃教
- Organizer
  World Congress of Gene 2008
- Place of Presentation
  中国, 佛山, Foshan Sanshui Garden Hotel
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Activation of Innate Immune Response Mediated by DNA-triggered Danger Signals2008
- Author(s)
 Takaoka, A.
- Organizer
 The 36^<th> Congress of the International Society of Oncology & BioMarkers
- Place of Presentation
 Tokyo, Japan
- Year and Date
 2008-10-06
- Data Source
 KAKENHI-PROJECT-20679003
[Presentation] Activation of Innate Immune Response Mediated by DNA-triggered Danger Signals2008
- Author(s)
  Takaoka, A
- Organizer
  The 36th Congress of the International Society of Oncology &BioMarkers
- Place of Presentation
  インターコンチネンタル東京ベイ
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] DNA Sensing Mechanism for the Activation of Innate Immune Responses2008
- Author(s)
  Takaoka, A
- Organizer
  BIT's 2nd World Congress of Gene 2008
- Place of Presentation
  Foshan Sanshui Garden Hotel (中国)
- Year and Date
  2008-12-06
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] Activation of Innate Immune Response Mediated by DNA-triggered Danger Signals2008
- Author(s)
  高岡晃教
- Organizer
  The 36th Congress of the International Society of Oncology & BioMarkers
- Place of Presentation
  インターコンチネンタル東京ベイ
- Year and Date
  2008-10-06
- Data Source
  KAKENHI-PROJECT-20015002
[Presentation] Novel function of DNA triggered innate immune responses2008
- Author(s)
  Takaoka, A
- Organizer
  The 8th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路島夢舞台国際会議場
- Data Source
  KAKENHI-PROJECT-20679003
[Presentation] 自然免疫応答を誘導する細胞質内DNAセンサーDAI(DLM-1/ZBP1)2007
- Author(s)
  高岡晃教
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-19390109
[Presentation] 自然免疫応答を誘導する細胞質内DNAセンサーDAI(DLM-1/ZBP1)2007
- Author(s)
  高岡晃教
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-19041021
[Presentation] Identification of DAI (DLM-1/ZBP1) as a cytosolic DNA sensor and actovator of innate immune response.2007
- Author(s)
  高岡晃教
- Organizer
  The 7th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2007-09-05
- Data Source
  KAKENHI-PROJECT-19041021
[Presentation] 自然免疫系を活性化する細胞質内DNAセンサーの同定2007
- Author(s)
  高岡晃教
- Organizer
  第72回日本インターフェロン・サイトカイン学会学術集会
- Place of Presentation
  京都大学百周年時計台記念館
- Year and Date
  2007-07-05
- Data Source
  KAKENHI-PROJECT-19041021
[Presentation] Direct and indirect roles of RIG-I for antiviral defense against hepatitis B virus in human hepatocytes
- Author(s)
  Akinori Takaoka
- Organizer
  International Conference on Antimicrobial Research
- Place of Presentation
  Madrid (Spain)
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25253030
[Presentation] Role of the cytoplasmic RNA sensor RIG-I in innate immune defense against hepatitis B virus infection
- Author(s)
  Akinori Takaoka
- Organizer
  11th International Conference on Innate Immunity
- Place of Presentation
  Olympia (Greece)
- Year and Date
  2014-06-01 – 2014-06-06
- Data Source
  KAKENHI-PROJECT-25253030
[Presentation] 免疫活性化機構解析を指向した光核酸類操作法による非天然核酸構造の構築
- Author(s)
  中村重孝,　藤本健造,　亀山武志,　高岡晃教
- Organizer
  第79回インターフェロン・サイトカイン学会
- Place of Presentation
  北海道大学医学部学友会館フラテ（北海道・札幌）
- Year and Date
  2014-06-19 – 2014-06-20
- Data Source
  KAKENHI-PROJECT-25640084

1. HONDA Kenya (60334231)

# of Collaborated Projects: 6 results

# of Collaborated Products: 35 results
2. KAMEYAMA Takeshi (40569505)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
3. SATO Seiichi (60459724)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. TANIGUCHI Tadatsugu (50133616)

# of Collaborated Projects: 2 results

# of Collaborated Products: 33 results
5. HAYAKAWA Sumio (00368292)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. TANAKA Nobuyuki (80222115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
7. TAMURA Tonohiko (50285144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. OOBA Yuusuke (30333503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
9. YANAI Hideyuki (70431765)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
10. ADACHI Yoshihiro Christopher (10616204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 高柳広 (20334229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 山田大翔 (10779333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 久米田博之 (00399966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OKADA Kanako

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. TODA Haruka

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 小原道法

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 小布施力史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takaoka Akinori 高岡 晃教

TAKAOKA Akinori 高岡 晃教

芫岡 晃教 タカオカ アキノリ

Research Projects

Research Products

Co-Researchers

lncRNAからエンコードされる新しい抗ウイルスサイトカインの同定と性状解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intrinsic immunityに着目した新しい抗ウイルス防御機構の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research on the immune system in uninfected cells that defines the immune response during viral infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The molecular mechanism of cancer specific cell death induction via novel innate immune signalingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Activation of innate immune response by DNA from food

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトサイトメガロウイルス感染により活性化されるパターン認識受容体活性化機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The novel post-transcriptional regulation mechanism of antiviral host defensePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of local and switchable innate immune activation by novel nucleic acid adjuvantPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウイルスＲＮＡと宿主ＲＮＡによって調節される細胞機能制御のメカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of activation of innate immune response by dietary nucleic acids via oral mucosa

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ウイルス感染におけるDNAを介する自然免疫応答の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がんに対するIFNを組み合わせた新しい抗体治療ストラテジーの開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms for the detection of microbes and cancer cells in innate immunityPrincipal Investigator

Principal Investigator

Takaoka Akinori 高岡晃教

TAKAOKA Akinori 高岡晃教

芫岡晃教タカオカアキノリ