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TSUDA Leo  津田 玲生

ORCIDConnect your ORCID iD *help
… Alternative Names

津田 怜生  ツダ レオ

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Researcher Number 30333355
Other IDs
Affiliation (based on the past Project Information) *help 2022 – 2023: 国立研究開発法人国立長寿医療研究センター, 研究所 認知症先進医療開発センター, 研究生
2021: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 研究生
2018 – 2020: 国立研究開発法人国立長寿医療研究センター, 認知症先進医療開発センター, 室長
2017: 国立研究開発法人国立長寿医療研究センター, その他部局等, 創薬モデル動物開発室 室長
2016 – 2017: 国立研究開発法人国立長寿医療研究センター, 創薬モデル動物開発室, 室長 … More
2015: 国立研究開発法人国立長寿医療研究センター, 治療薬探索研究部, 研究技術員
2012: 独立行政法人国立長寿医療研究センター, 創薬モデル動物開発研究プロジェクトチーム, プロジェクトリーダー
2011 – 2012: 独立行政法人国立長寿医療研究センター, 創薬モデル動物開発研究PT, プロジェクトリーダー
2011: 独立行政法人国立長寿医療研究センター, その他部局等, プロジェクトリーダー
2010: 独立行政法人国立長寿医療研究センター, 創薬モデル動物開発研究室, プロジェクトリーダー
2009 – 2010: 国立長寿センター, 老化機構研究部, 室長
2009: National Institute for Longevity Sciences,NCGG, 老化機構研究部, 室長
2008: 慶應義塾大学, 国立長寿センター・老化機構研究部, 室長
2007 – 2008: National Institute for Longevity Sciences,NCGG, 老化機構研究部, 室長
2005 – 2006: 国立長寿医療センター, (研究所)・老化機構研究部, 室長
2004: RIKEN, Morphogenetic Signaling Group, Researcher, 生態形成シグナル研究グループ, 研究員
2003 – 2004: 独立行政法人理化学研究所, 形態形成シグナル研究グループ, 研究員
2001 – 2002: 理化学研究所, 形態形成シグナル研究グループ, 研究員 Less
Review Section/Research Field
Principal Investigator
Biological Sciences / Developmental biology / ケミカルバイオロジー
Except Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Basic Section 51030:Pathophysiologic neuroscience-related / General internal medicine(including psychosomatic medicine) / Developmental biology / Otorhinolaryngology
Keywords
Principal Investigator
ショウジョウバエ / 転写コリプレッサー / 転写抑制 / シグナル伝達 / Ebi / 加齢性難聴 / 感覚器 / TBL1 / EGF / Notch … More / 神経発生 / REST / NRSF / Notchシグナル / 感覚細胞 / 細胞周期 / アポトーシス / ポリコーム / 神経変性 / AP-1 / 感音性難聴 / G1期抑制 / 転写リプレッサー / ヒストン修飾 / EGFシグナル / シグナル間クロストーク / コリプレッサー複合体 / ebi / クロマチン制御 / 転写 / ユビキチン化 / 蛋白質安定性 / F-box/WD40リピート / コヒーシン / クロマチン / ポリコーム複合体 / エピジェネティック / 加齢性疾患 / FOXO / 酸化ストレス応答 / 寿命制御 / テトラヒドロクルクミン / ポリフェノール / マウス / 加齢性感覚器障害 / 加齢 / ストレス応答 / ケミカルバイオロジー / 難聴 / G1期 / 恒常性維持 / 有毛細胞 / 老人性難聴 / トランスジェニックマウス / G1期制御 / Rb / 転写抑制因子 / p21 / ポリコーム群 / ユビキチンリガーゼ / E2F / 転写コリブレッサー / 細胞増殖 / Znフィンガー / 発生 / 神経 / 転写コリプレッサー複合体 / 複眼形成 / 光受容細胞 / 上皮増殖因子(EGF) / EBP / C / Egfrシグナル … More
Except Principal Investigator
アルツハイマー病 / ubiqitination / endocytosis / Deltex / Nedd4 / Notch / imaginal disc / ショウジョウバエ / Signaling / シナプス機能 / 加齢性難聴 / 神経変性疾患 / リン酸化イノシトール / ピログルタミル化 / シグナル伝達 / アミロイドβ / 神経変性 / 神経科学 / 痴呆 / 遺伝子型 / グリア / 糖尿病 / 肥満 / Drosophila / 細胞移動 / 翅 / 気管 / gfp / 成虫原基 / ユビキチン / エンドサイトーシス / 付属肢 / 難聴 / 医学 / 加齢 / 音響暴露 / 酸化障害 / 老化 / 聴覚 / 神経 / オートファジー / 活性酸素 / 有毛細胞 / 内耳障害 / 易受傷性 Less
  • Research Projects

    (14 results)
  • Research Products

    (92 results)
  • Co-Researchers

    (11 People)
  •  Molecular mechanism analysis of synaptic dysfunction common to Alzheimer's Disease and Age-related Hearing Loss

    • Principal Investigator
      Minami Ryunosuke
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Asahikawa Medical College
  •  Analysis of neurodegenerative control mechanism of Alzheimer's disease using a new model system

    • Principal Investigator
      LIM YOUNGMI
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Interactions between diabetes, aging and dementia

    • Principal Investigator
      Sato Naoyuki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Chromatin regulation by F-box/WD40 repeat proteinPrincipal Investigator

    • Principal Investigator
      TSUDA Leo
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Developmental biology
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  G1期抑制因子による感覚細胞の長期生存維持メカニズム解析Principal Investigator

    • Principal Investigator
      津田 玲生
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  Analysis of age-related sensory organ defects using Chemical BiologyPrincipal Investigator

    • Principal Investigator
      TSUDA Leo
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      ケミカルバイオロジー
    • Research Institution
      National Center for Geriatrics and Gerontology
  •  細胞周期抑制因子による感覚細胞の生存維持機構Principal Investigator

    • Principal Investigator
      津田 玲生
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute for Longevity Sciences,NCGG
  •  Differences of susceptibility and aging of inner damage

    • Principal Investigator
      OGAWA Kaoru
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      Keio University
  •  A molecular study of the co-repressor complex in the regulation ofee llular growth and differentiationPrincipal Investigator

    • Principal Investigator
      TSUDA Leo
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Developmental biology
    • Research Institution
      National Institute for Longevity Sciences,NCGG
  •  神経細胞の分化を制御する転写抑制因子の解析Principal Investigator

    • Principal Investigator
      津田 玲生
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      National Institute for Longevity Sciences,NCGG
      The Institute of Physical and Chemical Research
  •  EGFシグナルによる転写コリプレッサー複合体機能調節機構Principal Investigator

    • Principal Investigator
      津田 玲生
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Developmental biology
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Mechanisms of insect limb development

    • Principal Investigator
      HAYASHI Shigeo
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Developmental biology
    • Research Institution
      RIKEN
  •  転写コリプレッサー複合体、ebiの標的遺伝子解析Principal Investigator

    • Principal Investigator
      津田 玲生
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  EgfrとNotchシグナル間クロストークに関与するebiの機能解析Principal Investigator

    • Principal Investigator
      津田 玲生
    • Project Period (FY)
      2001
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research

All 2023 2021 2020 2019 2018 2017 2016 2015 2013 2012 2011 2010 2009 2008 2007 2006 Other

All Journal Article Presentation Book Patent

  • [Book] Advances in Experimental Medicine and Biology Series2018

    • Author(s)
      Tsuda L. and Lim YM.
    • Total Pages
      308
    • Publisher
      Springer Nature
    • ISBN
      9789811305290
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Book] 「G1期抑制因子による感覚細胞の長期生存維持メカニズム解析」、ヒトと医学のステージへ拡大する細胞周期、実験医学(増刊)312013

    • Author(s)
      津田玲生、林 永美
    • Publisher
      羊土社
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Book] ショウジョウバエを用いた老化研究、「脳内老化制御とバイオマーカー-基礎研究と食品素材-」2009

    • Author(s)
      津田玲生
    • Total Pages
      12
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-20058042
  • [Book] ショウジョウバエを用いた老化研究(脳内老化制御とバイオマーカー-基礎研究と食品食材-)(大澤俊彦, 丸山和佳子監修)2009

    • Author(s)
      津田玲生
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] Pyroglutamate-amyloid-β peptide expression in Drosophila leads to caspase-dependent and endoplasmic reticulum stress-related progressive neurodegeneration.2017

    • Author(s)
      Tsuda L, Omata Y, Yamasaki Y, Minami R, Lim YM.
    • Journal Title

      Human Molecular Genetics

      Volume: 26 Issue: 23 Pages: 4642-4656

    • DOI

      10.1093/hmg/ddx346

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Journal Article] Ebi, a Drosophila homologue of TBL1, regulates the balance between cellular defense responses and neuronal survival.2016

    • Author(s)
      Lim YM, Tsuda L.
    • Journal Title

      Am J Neurodegener Dis.

      Volume: 5 Pages: 62-68

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Journal Article] pGluAβ increases accumulation of Aβ in vivo 1 and exacerbates its toxicity.2016

    • Author(s)
      1) Sofola-Adesakin, O., Khericha, M., Snoeren, I., Tsuda, L., Partridge, L.
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 4 Issue: 1 Pages: 109-109

    • DOI

      10.1186/s40478-016-0380-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Journal Article] Expression of amyloid-β in mouse cochlear hair cells causes an early-onset auditory defect in high-frequency sound perception.2016

    • Author(s)
      Omata Y, Tharasegaran S, Lim YM, Yamasaki Y, Ishigaki Y, Tatsuno T, Maruyama M, Tsuda L.
    • Journal Title

      Aging (Albany NY).

      Volume: 8 Issue: 3 Pages: 427-440

    • DOI

      10.18632/aging.100899

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Journal Article] Nontoxic singlet oxygen generator as a therapeutic candidate for treating tauopathies.2015

    • Author(s)
      Mohideen SS, Yamasaki Y, Omata Y, Tsuda L, Yoshiike Y.
    • Journal Title

      Sci Rep.

      Volume: 5 Issue: 1 Pages: 10821-10821

    • DOI

      10.1038/srep10821

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Journal Article] Cellular Defense and Sensory Cell Survival Require Distinct Functions of ebi in Drosophila.2015

    • Author(s)
      Lim YM, Yagi Y, Tsuda L.
    • Journal Title

      PLoS One

      Volume: 10 Issue: 11 Pages: e0141457-e0141457

    • DOI

      10.1371/journal.pone.0141457

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Journal Article] Ebi/AP-1 suppresses pro-apoptotic gene expression and permits long-term survival of Drosophila sensory neurons.2012

    • Author(s)
      林 永美, 林 茂生, 津田玲生
    • Journal Title

      PLOS ONE

      Volume: 7

    • Data Source
      KAKENHI-PROJECT-22603017
  • [Journal Article] 老人性難聴の最前線2011

    • Author(s)
      津田玲生
    • Journal Title

      Human Science

      Volume: 21 Pages: 14-18

    • Data Source
      KAKENHI-PROJECT-22603017
  • [Journal Article] Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor2011

    • Author(s)
      Xiang, L., Nakamura, Y., Lim YM., Yamasaki, Y., Kurokawa-Nose, Y., Maruyama, W., Osawa, T., Matsuura, A., Tsuda, L
    • Journal Title

      Aging

      Volume: 3 Pages: 1098-1098

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Journal Article] Tetrahydrocurcumin extends life span and inhibits the oxldative stress response by regulating the FOXO forkhead transcription factor2011

    • Author(s)
      Xiang, L., Nakamura, Y., Lim YM., Yamasaki, Y., Kurokawa-Nose, Y., Maruyama, W., Osawa, T., Matsuura, A., Tsuda, L
    • Journal Title

      Aging

      Volume: 3 Pages: 1098-1098

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Journal Article] Robust specification of sensory neurons by dual functions of Charlatan, a Drosophila NRSF/REST-like repressor of extramacrochaetae and hairy.2011

    • Author(s)
      山崎泰豊, 林 永美, 林 茂生, 津田玲生
    • Journal Title

      Genes to Cell

      Volume: 16 Pages: 896-909

    • Data Source
      KAKENHI-PROJECT-22603017
  • [Journal Article] Robust specification of sensory neurons by dual functions of Charlatan, a Drosophila NRSF/REST-like repressor of extramacrochaetae and hairy2011

    • Author(s)
      Yamasaki, Y., Lim, YM., Hayashi, S., Tsuda, L
    • Journal Title

      Genes to Cell

      Volume: 16 Issue: 8 Pages: 896-896

    • DOI

      10.1111/j.1365-2443.2011.01537.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019045, KAKENHI-PLANNED-22111007, KAKENHI-PROJECT-22603017
  • [Journal Article] 老人性難聴の最前線2011

    • Author(s)
      津田玲生
    • Journal Title

      Human Science

      Volume: 21 Pages: 14-18

    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Journal Article] Tetrahydrocurcumin extends life span and inhibits the oxidative stress response by regulating the FOXO forkhead transcription factor.2011

    • Author(s)
      Xiang, L., 中村由貴子, 林 永美, 山崎泰豊, 能瀬-黒川 由美子, 丸山 和佳子, 大 澤俊彦, 松浦彰, 津田玲生
    • Journal Title

      Aging

      Volume: 3 Pages: 1098-1109

    • Data Source
      KAKENHI-PROJECT-22603017
  • [Journal Article] ショウジョウバエをモデルとした老化・加齢性神経疾患の研究-ケミカルジェネティックスによるアプローチ2008

    • Author(s)
      津田玲生
    • Journal Title

      ファルマシア 43

      Pages: 437-441

    • NAID

      10024377740

    • Data Source
      KAKENHI-PROJECT-20058042
  • [Journal Article] Dual function of Src in the maintenance of adherens junction during tracheal epithelial morphogenesis2008

    • Author(s)
      Shindo, M., Wada, H., Kaido, M., Tateno, M., Aigaki, T., Tsuda, I., Hayashi, S.
    • Journal Title

      Development 135

      Pages: 1355-1364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] ショウジョウバエをモデルとした老化・加齢性神経疾患の研究-ケミカルジェネティツクスによるアプローチ2008

    • Author(s)
      津田玲生
    • Journal Title

      基礎老化研究(基礎老化学会) 32

      Pages: 7-14

    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] Dual function of Src in the maintenance of adherens junction during tracheal epithelial morphogenesis.2008

    • Author(s)
      Shindo, M., Wada, H., Kaido, M., Tateno, M., Aigaki, T., Tsuda. L., and Hayashi, S.
    • Journal Title

      Development 135

      Pages: 1355-1364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20058042
  • [Journal Article] Dual function of Src in the maintenance of adherens junction during tracheal epithelial morphogenesis2008

    • Author(s)
      Shindo, M., Wada, H., Kaido, M., Tateno, M., Aigaki, T., Tsuda., L., Hayashi, S.
    • Journal Title

      Development 135

      Pages: 1355-1364

    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] Involvement of the mitochondrial protein translocator component tim 50 in growth, cell proliferation and the modulation of respiration in Drosophila.2007

    • Author(s)
      Sugiyama S, Moritoh S, Furukawa Y, Mizuno T, Lim YM, Tsuda L, Nishida Y.
    • Journal Title

      Genetics 176

      Pages: 927-936

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] Involvement of the mitochondrial protein translocator component Tim50 in growth, cell proliferation and the modulation of respiration in Drosophila2007

    • Author(s)
      Sugiyama, S., Montoh, S., Furukawa, Y., Mizuno., T., Lim, YM., Tsuda. L., Nishida, Y.
    • Journal Title

      Genetics 176

      Pages: 927-936

    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] 感覚細胞の生存維持からみた老人性難聴2007

    • Author(s)
      津田玲生
    • Journal Title

      ファルマシア(日本薬学会) 43

      Pages: 456-789

    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] An NRSF/REST-like repressor under negative control of Su(H)/SMRTER/Ebi repressor complex regulates eye development in Drosophila2006

    • Author(s)
      Tsuda, L., Kaido. M., Lim, Y. M., Kato, K., Aigaki, T., Hayashi, S.
    • Journal Title

      EMBO J. 25

      Pages: 3191-3202

    • Data Source
      KAKENHI-PROJECT-18370093
  • [Journal Article] Ebi/AP-1 suppresses pro-apoptotic gene expression and permits long-term survival of Drosophila sensory neurons

    • Author(s)
      Lim, YM., Hayashi, S., Tsuda, L.
    • Journal Title

      PLoS ONE

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Journal Article] Ebi/AP-1 suppresses pro-apoptotic gene expression and permits long-term survival of Drosophila sensory neurons

    • Author(s)
      Lim, YM., Hayashi, S., Tsuda, L
    • Journal Title

      PLoS ONE

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Patent] アミロイドβ42蓄積抑制用組成物、並びに、アルツハイマー型認知症予防治療用組成物及び脳アミロイドアンギオパチー予防治療用組成物2020

    • Inventor(s)
      津田玲生、林 永美、立崎 仁、國吉智子
    • Industrial Property Rights Holder
      津田玲生、林 永美、立崎 仁、國吉智子
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Patent] 遺伝子組換え無脊椎動物アルツハイマー病モデルおよびその利用2017

    • Inventor(s)
      山崎泰豊、柳澤勝彦、津田玲生
    • Industrial Property Rights Holder
      国立長寿医療研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2017-099855
    • Filing Date
      2017
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Patent] トランスジェニック非化動物の確立および認知症の治療薬スクリーニング法確立2011

    • Inventor(s)
      津田玲生, 林永美
    • Industrial Property Rights Holder
      財団法人ヒューマンサイエンス振興財団
    • Industrial Property Number
      2011-085642
    • Filing Date
      2011-04-07
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Patent] トランスジェニック非ヒト動物の確立および認知症の治療薬スクリーニング法確立2011

    • Inventor(s)
      津田玲生, 林永美
    • Industrial Property Rights Holder
      財団法人ヒューマンサイエンス振興財団
    • Industrial Property Number
      2011-085642
    • Filing Date
      2011-04-07
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Patent] トランスジェニック非ヒト動物の確立および認知症の治療薬スクリーニング法確立2011

    • Inventor(s)
      津田玲生、林 永美
    • Industrial Property Rights Holder
      ヒューマンサイエンス振興財団
    • Industrial Property Number
      2011-085642
    • Filing Date
      2011-04-07
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Patent] クルクミン代謝物、テトラヒドロクルクミンの抗老化作用2006

    • Inventor(s)
      大澤 俊彦, 向 蘭, 丸山 和佳子, 津田 玲生, 松浦 彰
    • Industrial Property Rights Holder
      大澤 俊彦
    • Filing Date
      2006-01-10
    • Data Source
      KAKENHI-PROJECT-18370093
  • [Presentation] アミロイドβが引き起こすシナプス機能障害の分子メカニズム2023

    • Author(s)
      南竜之介, 林永美, 津田玲生
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K11618
  • [Presentation] Searching for the therapeutic drugs for AD using Drosophila and mouse2021

    • Author(s)
      Tsuda L., Minami R., Lim YM
    • Organizer
      AD/PD 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] 孤発性アルツハイマー病の発症と栄養素の関係2021

    • Author(s)
      南 竜之介、林 永美、津田 玲生
    • Organizer
      第32回 日本老年学会総会 合同シンポジウム「認知症と栄養」
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] アミロイドβによるシナプス機能低下の誘導メカニズム解析2020

    • Author(s)
      南竜之介、林永美、津田玲生
    • Organizer
      第39回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] アルツハイマー病における神経変性誘導メカニズム解析2020

    • Author(s)
      林永美、津田玲生
    • Organizer
      第39回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] アミロイドβ によるシナプス機能低下の誘導メカニズム解析2020

    • Author(s)
      南竜之介, 林永美, 津田玲生
    • Organizer
      第39回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K11618
  • [Presentation] 内耳有毛細胞と神経細胞の共通性に着目したアルツハイマー病研究2020

    • Author(s)
      津田玲生、南 竜之介、林 永美
    • Organizer
      第43回日本分子生物学会年会 ワークショップ
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] ショウジョウバエとマウスを組み合わせたアルツハイマー病治療薬の開発研究2020

    • Author(s)
      林 永美、南 竜之介、津田玲生
    • Organizer
      第43回日本分子生物学会年会 ワークショップ
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] Induction of ganglioside synthesis accelerates assembly of amyloidβprotein in the brain.2019

    • Author(s)
      Yamasaki Y., Lim YM., Tsuda L.
    • Organizer
      International conference on Alzheimer’s and Parkinson’s diseases (AD/PD 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] ショウジョウバエの脳神経で発現させたガングリオシドの機能解析.2019

    • Author(s)
      津田玲生、山崎泰豊、林 永美
    • Organizer
      第52回日本発生生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] 創薬モデル動物を用いたアルツハイマー病治療薬の開発2019

    • Author(s)
      林永美、南竜之介、津田玲生
    • Organizer
      第38回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] 孤発性アルツハイマー病の発症における加齢と蛋白質代謝の役割2019

    • Author(s)
      津田玲生
    • Organizer
      第5回生体調節研究所 内分泌代謝シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] Importance of nutrients in the late onset of Alzheimer’s disease associated with aging.2019

    • Author(s)
      南竜之介、林永美、津田玲生
    • Organizer
      第42回日本分子生物学会年会 ワークショップ
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] アミロイドβによるシナプス機能低下と加齢の関係.2019

    • Author(s)
      津田玲生
    • Organizer
      第42回日本基礎老化学会大会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] 聴覚機能を用いたアミロイドβ(Aβ)によるシナプス機能低下の分子機構解析.2019

    • Author(s)
      南竜之介、林永美、津田玲生
    • Organizer
      第38回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] Chemical biological approaches to identify therapeutic drugs for Alzheimer’s disease using mouse and Drosophila in vivo model systems2019

    • Author(s)
      Lim YM., Yamasaki Y., Minami R., Tsuda L.
    • Organizer
      International conference on Alzheimer’s and Parkinson’s diseases (AD/PD 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] Development of therapeutics for Alzheimer’s disease using chemical biological approaches.2019

    • Author(s)
      津田玲生、南竜之介、林永美
    • Organizer
      第42回日本分子生物学会年会 ワークショップ
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] 新規アルツハイマー病(AD)モデルマウスにおける神経機能低下の分子メカニズム解析2018

    • Author(s)
      南竜之介、林 永美、津田玲生
    • Organizer
      第37回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] Charlatan, a Drosophila NREF/REST, is implicated in the neuronal diversity formation2018

    • Author(s)
      林永美、山崎泰豊、南竜之介、津田玲生
    • Organizer
      第13回日本ショウジョウバエ研究会学術集会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] 加齢性神経疾患の研究における内耳有毛細胞と神経細胞との分子的共通性2018

    • Author(s)
      南 竜之介、林 永美、津田玲生
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] Analysis of neuronal dysfunction mechanism common to dementia and senile deafness.2018

    • Author(s)
      Minami R., Lim YM., Tsuda L.
    • Organizer
      第41回日本基礎老化学会大会
    • Data Source
      KAKENHI-PROJECT-18K07405
  • [Presentation] ケミカルバイオロジーによるアルツハイマー病(AD)治療薬の開発研究2017

    • Author(s)
      南 竜之介、林 永美、山崎泰豊、津田玲生
    • Organizer
      第36回日本認知症学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] Ab(pE3-42) in Drosophila leads to endoplasmic reticulum stress related neurodegeneration2017

    • Author(s)
      Lim Y., Tsuda L.
    • Organizer
      第40回日本基礎老化学会大会
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] ショウジョウバエNRSF/REST相同因子Charlatanの転写後修飾による神経機能調節機構2017

    • Author(s)
      林 永美、山崎泰豊、南 竜之介、津田玲生
    • Organizer
      第40回日本分子生物学会学術集会
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] Chemical genetic approach to identify the therapeutic drugs for Alzheimer’s disease using Drosophila and mouse model2017

    • Author(s)
      Tsuda L.
    • Organizer
      4th Asia-Pacific Drosophila Research Conference (APDRC4)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] Establishment of new Alzheimer’s disease mouse model using auditory hair cells2017

    • Author(s)
      Lim Y., Tsuda L.
    • Organizer
      Keystone Symposium, Aging and Mechanisms of Aging-Related Disease (E2)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] Ubiquitin-modifications of Charlatan, a Drosophila NRSF/REST, is required for the inversible regulation of neuron specific genes expression2016

    • Author(s)
      Leo Tsuda, Yasutoyo Yamasaki, Young-Mi Lim
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] ショウジョウバエを用いた疾患研究の最前線:遺伝学とケミカルバイオロジーの融合2016

    • Author(s)
      津田玲生
    • Organizer
      第68回日本細胞生物学会年会
    • Place of Presentation
      京都
    • Year and Date
      2016-06-15
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] アルツハイマー病の発症に伴った神経変性の定量的解析モデル作成2016

    • Author(s)
      津田玲生
    • Organizer
      第35回日本認知症学会学術集会
    • Place of Presentation
      東京
    • Year and Date
      2016-12-01
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] Post-translational modification of Charlatan, a Drosophila NRSF/REST, is required for neuron specific genes expression.2015

    • Author(s)
      1) 津田玲生、山崎泰豊、林 永美
    • Organizer
      第58回日本神経化学会大会シンポジウム
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K07092
  • [Presentation] Molecular study of age-related hearing disorders.2013

    • Author(s)
      Lim YM, Omata Y, Yamasaki Y, Tsuda L
    • Organizer
      54th Drosophila Research Conference
    • Place of Presentation
      Washington DC, USA
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Chemical Genetic approach to evaluate the toxicity of Amyloid-beta using Drosophila.2013

    • Author(s)
      Tsuda L., Omata Y., Yamasaki Y., Lim YM.
    • Organizer
      11^<th> International Conference on Alzheimer's & Parkinson's Diseases (AD/PD 2013)
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Post-translational modification of Charlatan, a Drosophila NRSF/REST-like repressor, is required for neuron specific genes expression.2012

    • Author(s)
      Lim, YM, Yamasaki, Y., Tsuda L.
    • Organizer
      British Society for Developmental Biology, British Society for Cell Biology and Japanese Society of Developmental Biologists Joint meeting
    • Place of Presentation
      Bermingham, UK
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila.2011

    • Author(s)
      Lim Y., Tsuda , L.
    • Organizer
      52th Drosophila Research Conference
    • Place of Presentation
      San Diego
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila2011

    • Author(s)
      Tsuda L.
    • Organizer
      Exciting Biology Series "Celluar Development : Biology at the interface" sponcered by Developmental Cell
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila2011

    • Author(s)
      Lim Y., Tsuda, L.
    • Organizer
      52th Drosophila Research Conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-04-01
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila.2011

    • Author(s)
      Tsuda L., Yamasaki, Y., Lim, YM.
    • Organizer
      Exciting Biology Series" Celluar Development: Biology at the interface" sponcered by Developmental Cell
    • Place of Presentation
      Kobe, Japan
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila2011

    • Author(s)
      Lim Y., Tsuda, L.
    • Organizer
      52th Drosophila Research Conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-04-01
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Presentation] Ebi alleviates excess growth stimulation through its multiple functions against E2f in Drosophila2011

    • Author(s)
      Leo Tsuda
    • Organizer
      52^<nd> Drosophila research conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-31
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila2011

    • Author(s)
      Tsuda L.
    • Organizer
      Exciting Biology Series "Celluar Development : Biology at the interface" sponcered by Developmental Cell
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2011-09-30
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Presentation] Ebi alleviates excess growth stimulation through its multiple functions against E2f in Drosophila2011

    • Author(s)
      Leo Tsuda
    • Organizer
      52^<nd> Drosophila research conference
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-03-31
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] 細胞増殖と細胞分化のスイッチング機構2010

    • Author(s)
      津田玲生
    • Organizer
      第33回に本分子生物学会年会、ワークショップ
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Presentation] 細胞増殖と細胞分化のスイッチング機構2010

    • Author(s)
      津田玲生
    • Organizer
      第33回に本分子生物学会年会、ワークショップ
    • Place of Presentation
      神戸
    • Year and Date
      2010-12-10
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] ショウジョウバエを用いた加齢性難聴の発症メカニズム解析2010

    • Author(s)
      津田玲生
    • Organizer
      第29回聴覚生理研究会
    • Place of Presentation
      松山
    • Year and Date
      2010-10-07
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Presentation] Molecular Study of Age-related Sensorineural Hearing Loss using Drosophila2010

    • Author(s)
      Leo Tsuda
    • Organizer
      Cold Spring Harbor Symposium : Molecular Aging
    • Place of Presentation
      NY, USA
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] ショウジョウバエを用いた加齢性難聴の発症メカニズム解析2010

    • Author(s)
      津田玲生
    • Organizer
      第29回聴覚生理研究会
    • Place of Presentation
      松山
    • Year and Date
      2010-10-07
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular study of age-related sensorineural hearing loss using Drosophila.2010

    • Author(s)
      Tsuda, L., Lim Y.
    • Organizer
      CSH symposium Molecular Genetics of Aging
    • Place of Presentation
      CSH, NY
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Molecular Study of Age-related Sensorineural Hearing Loss using Drosophila2010

    • Author(s)
      Leo Tsuda
    • Organizer
      Cold Spring Harbor Symposium : Molecular Aging
    • Place of Presentation
      NY, USA
    • Year and Date
      2010-09-30
    • Data Source
      KAKENHI-PUBLICLY-22019045
  • [Presentation] Molecular Mechanism of Neuronal Maturation.2009

    • Author(s)
      Tsuda, L
    • Organizer
      The Amarican Society for Cell Biology/Japan Society for Cell Biology/RLKEN Center for Developmental Biology Meeting
    • Place of Presentation
      Kyoto
    • Year and Date
      2009-10-07
    • Data Source
      KAKENHI-PROJECT-20058042
  • [Presentation] Molecular study of age-related hearing disorders using Drosophila melanogaster.2009

    • Author(s)
      Tsuda, L
    • Organizer
      Ilsong Mini Synposium
    • Place of Presentation
      Korea
    • Year and Date
      2009-04-29
    • Data Source
      KAKENHI-PROJECT-20058042
  • [Presentation] ショウジョウバエモデルを用いた加齢性感覚器障害の発症メカニズム解析2009

    • Author(s)
      津田玲生
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Year and Date
      2009-12-10
    • Data Source
      KAKENHI-PROJECT-20058042
  • [Presentation] ショウジョウバエNRSF/REST様因子 charlatan の翻訳後修飾と核内局在の調節機構2008

    • Author(s)
      Young-Mi Lim, 山崎泰豊, 林茂生, 津田玲生
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-18370093
  • [Presentation] ショウジョウバエNRSF/REST様因子charlatanの翻訳後修飾と核内局在の調節機構2008

    • Author(s)
      Young-Mi Lim, 山崎泰豊、林茂生、津田玲生
    • Organizer
      第31回日本分子生物学会
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-10
    • Data Source
      KAKENHI-PROJECT-20058042
  • [Presentation] A nuclear factor, ebi, inhibits G1-S transition by regulating E2F activity during photoreceptor cells development in Drosophila2008

    • Author(s)
      Leo Tsuda
    • Organizer
      41^<st> Annual Meeting for the Japanese Society of Developmental Biology
    • Place of Presentation
      Tokushima
    • Year and Date
      2008-05-28
    • Data Source
      KAKENHI-PROJECT-18370093
  • [Presentation] Post-translational modification of Charlatan, a Drosophila NRSF/REST-like repressor, is required for neuron specific genes expression.

    • Author(s)
      Leo Tsuda
    • Organizer
      British Society for Developmental Biology, British Society for Cell Biology and Japanese Society of Developmental Biologists Joint meeting, Bermingham, UK
    • Place of Presentation
      Bermingham, UK
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] Chemical Genetic approach to evaluate the toxicity of Amyloid-beta using Drosophila.

    • Author(s)
      Leo Tsuda
    • Organizer
      11th International Conference on Alzheimer’s & Parkinson’s Diseases (AD/PD 2013)
    • Place of Presentation
      Florence, Italy
    • Data Source
      KAKENHI-PROJECT-22603017
  • [Presentation] 増殖停止における遺伝子発現抑制の役割

    • Author(s)
      津田玲生
    • Organizer
      第35回日本分子生物学会年会・ワークショップ
    • Place of Presentation
      福岡
    • Invited
    • Data Source
      KAKENHI-PROJECT-22603017
  • 1.  LIM Young-mi (60421898)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 52 results
  • 2.  HAYASHI Shigeo (60183092)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  山崎 泰豊 (90435876)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  OGAWA Kaoru (00169179)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KANZAKI Sho (50286556)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  INOUE Yoshiko (60217916)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Sato Naoyuki (70372612)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Minami Ryunosuke (90806895)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  村山 繁雄 (50183653)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  櫻井 孝 (50335444)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  宮崎 早月 (60452439)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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