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IMATANI Akira  今谷 晃

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今谷 晃  イマタニ アキラ

Imatani Akira  今谷 晃

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Researcher Number 30333876
Other IDs
Affiliation (Current) 2025: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2025: 東北大学, 医学系研究科, 教授
2022 – 2023: 東北大学, 医学系研究科, 教授
2016 – 2020: 東北大学, 医学系研究科, 教授
2015: 東北大学, 医学(系)研究科(研究院), 教授
2011 – 2013: 東北大学, 医学(系)研究科(研究院), 教授 … More
2010: Tohoku University, 病院, 講師
2009: Tohoku University, 病院, 助教
2008: Tohoku University, 大学院・医学系研究科, 助教
2005 – 2006: 東北大学, 高等教育開発推進センター, 助手
2004: 東北大学, 大学院・情報科学研究所, 助手
2002 – 2004: 東北大学, 大学院・情報科学研究科, 助手
2002: 東北大学, 大学院・情報科学研究所, 助手
2001: 東北大学, 保健管理センター, 助手 Less
Review Section/Research Field
Principal Investigator
Gastroenterology / Basic Section 53010:Gastroenterology-related / Gastroenterology
Except Principal Investigator
Gastroenterology / 広領域
Keywords
Principal Investigator
発現制御 / 分化制御 / 胃 / 幹細胞老化 / 胃発癌 / 加齢 / 胃粘膜萎縮 / 細胞老化 / differentiation / Cdx2 … More / シグナル伝達 / 発生・分化 / ヒト胃オルガノド / Wnt/beta-cateninシグナル / 胃発がん / ヒト胃オルガノイド / 3次元細胞培養 / 胃オルガノイド / Helicobacter / DNAメチル化 / Notch1 / エピジェネティック / 胃癌 / stomach / immunology / signaling / regulation of expression / 免疫学 / gastric culture cells / NFkB / upper GI tract / Notch genes / Sodium butyrate / 分化マーカー / 癌化メカニズム / 胃癌培養細胞株 / NFκB / 上部消化管 / Notch遺伝子 / マイクロアレイ / 癌幹細胞 / 分化 / 癌抑制遺伝子 / Helicobacter pylori / 癌 / 幹細胞 … More
Except Principal Investigator
MSX2 / Notch / oncogenesis / regeneration / 膵再生 / 膵癌 / fiber optic probe / optical biopsy / Ti:sapphire laser / raman specrtoscopy / mono-l-aspartyl chlorin e6(Npe 6) / photodynamic therapy / 消化器腫瘍 / 光ファイバー / 生体分光 / 波長可変レーザー / ラマン散乱 / 光ファイバープローブ / 消化管腫瘍診断 / チタンサファイアレーザー / ラマン分光 / Npe6 / 光線力学的治療 Less
  • Research Projects

    (10 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (11 People)
  •  胃オルガノイドに基づく加齢に伴う幹細胞老化が関わる胃発癌誘導機序の解明Principal Investigator

    • Principal Investigator
      今谷 晃
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  ヒト胃オルガノイド培養に基づく幹細胞老化に伴う発癌ポテンシャル獲得機序の解明Principal Investigator

    • Principal Investigator
      今谷 晃
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Analysis of the gastric carcinogenesis with ageing based on the murine organoid modelPrincipal Investigator

    • Principal Investigator
      Imatani Akira
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Tohoku University
  •  Gastric carcinogenesis mechanism by impaired expression of Notch1 receptor through the deviation from cellular senescencePrincipal Investigator

    • Principal Investigator
      Imatani Akira
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Mechanism of Gastric Carcinogenesis in the progression to mucosal atrophy and intestinal metaplasia through Notch1 signalingPrincipal Investigator

    • Principal Investigator
      IMATANI AKIRA
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Identification of novel genes related with stem cell and cancer stem cell in the transdifferentiation to gastric intestinal mataplasia.Principal Investigator

    • Principal Investigator
      IMATANI Akira
    • Project Period (FY)
      2008 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Analysis of differentiation system in the stomach by the immune response to Helicobactor pylori infectionPrincipal Investigator

    • Principal Investigator
      IMATANI Akira
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Elucidation of regeneration-mechanisms through notch signaling and establishment of novel stem cell transplantation in pancreas

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      2002 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Gastroenterology
    • Research Institution
      Tohoku University
  •  Analysis of carcinogenesis and differentiation by Notch genes in human digestive tractPrincipal Investigator

    • Principal Investigator
      IWATANI Akira
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      TOHOKU UNIVERSITY
  •  Fiber-optic approaches for diagnosis of gastrointestinal disease

    • Principal Investigator
      SHIMOSEGAWA Tooru
    • Project Period (FY)
      2000 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      広領域
    • Research Institution
      Tohoku University

All 2023 2014 2013 2010

All Presentation

  • [Presentation] Aberrant TBX3 induction may contribute to aging-related gastric carcinogenesis via suppression of cellular senescence2023

    • Author(s)
      Masashi Saito, Naoki Asano, Akira Imatani, Xiaoyi Jin, Atsushi Masamune
    • Organizer
      第82回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K08025
  • [Presentation] Evasion of cellular senescence mediated by aberrant TBX3 induction may contribute to aging-related carcinogenesis in human gastric cancers2023

    • Author(s)
      Masashi Saito, Naoki Asano, Akira Imatani, Akio Takeuchi, Xiaoyi Jin, Masahiro Saito, Takeshi Kanno, Waku Hatta, Kaname Uno, Tomoyuki Koike, and Atsushi Masamune
    • Organizer
      DDW2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K08025
  • [Presentation] Loss of Notch1 function in Helicobacter pylori contributes to gastric mucosal atrophy and carcinogenesis.2014

    • Author(s)
      Xiaoyi Jin, Naoki Asano, Akira Imatani, Jun Fushiya, Yutaka Kondo, Katsunori Iijima, Tomoyuki Koike, Tooru Shimosegawa
    • Organizer
      Digestive Disease Week 2014
    • Place of Presentation
      Chicago, United State of America
    • Data Source
      KAKENHI-PROJECT-23590910
  • [Presentation] Loss of Notch1 function in Helicobacter pylori contributes to gastric mucosal atrophy and carcinogenesis.2014

    • Author(s)
      Xiaoyi Jin, Naoki Asano, Akira Imatani, Jun Fushiya, Yutaka Kondo, Katsunori Iijima, Tomoyuki Koike, Tooru Shimosegawa
    • Organizer
      Digestive Disease Week
    • Place of Presentation
      アメリカ合衆国・シカゴ
    • Year and Date
      2014-05-04
    • Data Source
      KAKENHI-PROJECT-23590910
  • [Presentation] Helicobacter pylori infection induces the atrophy of gastric mucosa through the down-regulation of Notch1 and Sox2.2013

    • Author(s)
      Xiaoyi Jin, Akira Imatani, Naoki Asano, Yutaka Kondo, Jun Fushiya, Nobuyuki Ara, Katsunori Iijima, Tomoyuki Koike, Tooru Shimosegawa
    • Organizer
      NIH-Tohoku University-JSPS Symposium
    • Place of Presentation
      仙台
    • Year and Date
      2013-05-10
    • Data Source
      KAKENHI-PROJECT-23590910
  • [Presentation] H.pylori感染胃粘膜におけるHMGボックス遺伝子Sox2発現抑制による腸上皮化生進展の機序2010

    • Author(s)
      今谷晃、阿曽沼祥、浅野直喜、近藤穣、千葉隆士、伏谷淳、下瀬川徹
    • Organizer
      第9回消化器病フォーラム
    • Place of Presentation
      東京
    • Year and Date
      2010-11-20
    • Data Source
      KAKENHI-PROJECT-20590716
  • [Presentation] Downregulation of embryonic stem cell-related gene Sox2 induced transdifferentiation to intestinal etaplasia in Helicobacter pylori infected gastric mucosa2010

    • Author(s)
      Yutaka Kondo, Akira Imatani, Sho Asonuma, Hidetomo Konishi, Takashi Chiba, Naoki Asano, Kaname Uno, Yasuhiko Abe, Katsunori Iijima, Tomoyuki Koike, Tooru Shimosegawa
    • Organizer
      第1回 International Topic Conference(日本消化器病学会)
    • Place of Presentation
      鎌倉
    • Year and Date
      2010-09-25
    • Data Source
      KAKENHI-PROJECT-20590716
  • 1.  SHIMOSEGAWA Tooru (90226275)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  OHARA Shuichi (40223929)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  ASAKURA Tohru (20272023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  TASHIRO Hideo (90124370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SATO Hidetoshi (10300873)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  AIZAWA Katuo (40074645)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KIMURA Kenji (90359513)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SEKINE Hitoshi (90241596)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  IIJIMA Katunori (60375003)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  佐藤 賢一 (10282055)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  池田 照樹
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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