Tomi Masatoshi 登美斉俊

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TOMI Masatoshi 登美斉俊

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Researcher Number	30334717
Other IDs
External Links
Affiliation (Current)	2025: 慶應義塾大学, 薬学部(芝共立), 教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 慶應義塾大学, 薬学部(芝共立), 教授 2016: 慶應義塾大学, 薬学部, 教授 2011 – 2015: 慶應義塾大学, 薬学部, 准教授 2009 – 2010: Keio University, 薬学部, 講師 2006: 富山大, 薬学部, 助手 2005: 富山大学, 薬学部, 助手 2002 – 2004: 富山医科薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Medical pharmacy / Basic Section 47060:Clinical pharmacy-related / Eating habits / Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 59040:Nutrition science and health science-related / 応用薬理学・医療系薬学 Except Principal Investigator Medical pharmacy / Applied pharmacology
Keywords	Principal Investigator 胎盤関門 / トランスポーター / 胎盤 / 有機アニオン / 内側血液網膜関門 / 生理学的薬物速度論モデル / 妊婦 / 生理学的薬物動態モデル / カチオントランスポーター / アミノ酸トランスポーター … More / miRNA / メチル基供与体 / 内分泌 / 分化 / CNT2 / OAT4 / 血液胎盤関門 / ヌクレオシド / エネルギー代謝 / 妊娠 / クレアチン / 胎児栄養環境 / 発現制御 / Oat3 / Oatp2 / 排出輸送 / 網膜 / 輸送担体 / 血液脳関門 / TR-BBB細胞 / TR-iBRB細胞 / 条件的不死化細胞株 … More Except Principal Investigator GLUT1 / vitamin C / 血管新生 / 浸透圧 / 胎児発育不全 / 発現調節 / アミノ酸 / トランスポーター / 胎児成長 / 胎盤 / transport mechanism / TR-iBRB cells / diabetes / antioxidant / oxidative stress / blood-retinal barrier / 条件的不死化細胞株 / 担体輸送 / 輸送機構 / TR-iBRB細胞 / 糖尿病 / 抗酸化物質 / 酸化的ストレス / 血液網膜関門 / 微小血管密度低下 / タキサン系抗がん剤 / 遊走能 / 骨髄由来血管内皮細胞 / 腫瘍増殖抑制 / 抗がん剤 / CD133 / 抗がん薬 / 血管新生阻害 / 管腔形成能 / ケモタキシス / SMA / bFGF / 壁細胞 / 血管内皮前駆細胞 / 代謝学 / 薬物動態 / MAPK / PKC / 網膜ペリサイト株 / リコンビナントタンパク / 網膜毛細血管内皮細胞 / 細胞増殖抑制因子 / 網膜ペリサイト Less

Ex vivo-in silicoハイブリッドによるヒト胎児薬物移行の新解析プラットフォーム構築Principal Investigator
- Principal Investigator
  
  登美斉俊
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Keio University
Prediction model for transplacental drug exposure to the human fetus based on species differences in placental transporters and plasma unbound concentrationsPrincipal Investigator
- Principal Investigator
  
  Tomi Masatoshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47060:Clinical pharmacy-related
- Research Institution
  Keio University
Regulation of pharmacokinetics during pregnancy by placental exosomesPrincipal Investigator
- Principal Investigator
  
  Tomi Masatoshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Keio University
Significance of a balanced tryptophan diet for supporting fetal growthPrincipal Investigator
- Principal Investigator
  
  Tomi Masatoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Keio University
Functional expression of sensing foctors against maternal osmotic stress in the placenta
- Principal Investigator
  
  NISHIMURA Tomohiro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Keio University
Medication for pregnant women based on 'barrier transition' behavior in feto-placental circulationPrincipal Investigator
- Principal Investigator
  
  Tomi Masatoshi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University
Food guide for pregnant women based on placental permeability of ingredientsPrincipal Investigator
- Principal Investigator
  
  Tomi Masatoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Eating habits
- Research Institution
  Keio University
Fetal transfer mechanism of methyl donors across the placenta and its epigeneomesPrincipal Investigator
- Principal Investigator
  
  TOMI Masatoshi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Eating habits
- Research Institution
  Keio University
Molecular basis of mechanisms underlying transplacental drugtransfer in corporation with placental endocrine functionPrincipal Investigator
- Principal Investigator
  
  TOMI Masatoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University
Establishment of human cell lines for blood-tissue barrier and application to elucidate mechanism of low-dose anti-cancer drugs
- Principal Investigator
  
  NAKASHIMA Emi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University
Regulation mechanisms of the placental barrier for the maintenance of the fetal environment and their relevancies to the phenotypePrincipal Investigator
- Principal Investigator
  
  TOMI Masatoshi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Medical pharmacy
- Research Institution
  Keio University
血液網膜関門薬物排出輸送を制御する分子機構の解明Principal Investigator
- Principal Investigator
  
  登美斉俊
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  University of Toyama
網膜ペリサイト分泌血管内皮細胞増殖抑制因子の同定
- Principal Investigator
  
  HOSOYA Ken-ichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Medical pharmacy
- Research Institution
  Toyama Medical and Pharmaceutical University
Antioxidants transport via GLUT1 at the blood-retinal barrier
- Principal Investigator
  
  HOSOYA Ken-ichi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  TOYAMA MEDICAL AND PHARMACEUTICAL UNIVERSITY
血液網膜関門特異的遺伝子の探索と機能解明Principal Investigator
- Principal Investigator
  
  登美斉俊
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Toyama Medical and Pharmaceutical University

[Journal Article] Breast Cancer Resistance Protein Limits Fetal Transfer of Tadalafil in Mice2024
- Author(s)
  Nishimura Tomohiro、Ishii Mari、Tanaka Hiroaki、Noguchi Saki、Ikeda Tomoaki、Tomi Masatoshi
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 113 Issue: 2 Pages: 486-492
- DOI
  10.1016/j.xphs.2023.11.006
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06750, KAKENHI-PROJECT-21H02651
[Journal Article] Conversion of Olmesartan to Olmesartan Medoxomil, A Prodrug that Improves Intestinal Absorption, Confers Substrate Recognition by OATP2B12024
- Author(s)
  Fukazawa Naomi、Nishimura Tomohiro、Orii Keisuke、Noguchi Saki、Tomi Masatoshi
- Journal Title
  
  Pharmaceutical Research
  
  Volume: － Issue: 5 Pages: 849-861
- DOI
  10.1007/s11095-024-03687-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21H02651
[Journal Article] L-type Amino Acid Transporter 1 (SLC7A5)-Mediated Transport of Pregabalin at the Rat Blood-Spinal Cord Barrier and its Sensitivity to Plasma Branched-Chain Amino Acids2023
- Author(s)
  Akashi Tomoya、Noguchi Saki、Takahashi Yu、Nishimura Tomohiro、Tomi Masatoshi
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 112 Issue: 4 Pages: 1137-1144
- DOI
  10.1016/j.xphs.2022.12.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K20723, KAKENHI-PROJECT-21H02651
[Journal Article] Role of Uptake Transporters OAT4, OATP2A1, and OATP1A2 in Human Placental Bio-disposition of Pravastatin2022
- Author(s)
  Fokina Valentina M.、Patrikeeva Svetlana、Wang Xiao-ming、Noguchi Saki、Tomi Masatoshi、Konig Jorg、Ahmed Mahmoud S.、Nanovskaya Tatiana
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 111 Issue: 2 Pages: 505-516
- DOI
  10.1016/j.xphs.2021.09.035
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16056, KAKENHI-PROJECT-21H02651
[Journal Article] Transplacental pharmacokinetic model of digoxin based on ex vivo human placental perfusion study.2022
- Author(s)
  Kurosawa K., Noguchi S., Nishimura T., Tomi M., Chiba K..
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 50(3) Issue: 3 Pages: 287-298
- DOI
  10.1124/dmd.121.000648
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08470, KAKENHI-PROJECT-20K16056, KAKENHI-PROJECT-21H02651
[Journal Article] Limited Impact of Murine Placental MDR1 on Fetal Exposure of Certain Drugs Explained by Bypass Transfer Between Adjacent Syncytiotrophoblast Layers2022
- Author(s)
  Fujita Arimi、Noguchi Saki、Hamada Rika、Inoue Satoko、Shimada Tsutomu、Katakura Satomi、Maruyama Tetsuo、Sai Yoshimichi、Nishimura Tomohiro、Tomi Masatoshi
- Journal Title
  
  Pharmaceutical Research
  
  Volume: - Issue: 7 Pages: 1645-1658
- DOI
  10.1007/s11095-022-03165-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16056, KAKENHI-PROJECT-20K22703, KAKENHI-PROJECT-20H03826, KAKENHI-PROJECT-21H02651
[Journal Article] Quantitative Comparison of Breast Cancer Resistance Protein (BCRP/ABCG2) Expression and Function Between Maternal Blood-Brain Barrier and Placental Barrier in Mice at Different Gestational Ages2022
- Author(s)
  Fujita Arimi、Noguchi Saki、Hamada Rika、Shimada Tsutomu、Katakura Satomi、Maruyama Tetsuo、Sai Yoshimichi、Nishimura Tomohiro、Tomi Masatoshi
- Journal Title
  
  Frontiers in Drug Delivery
  
  Volume: 2 Pages: 932576-932576
- DOI
  10.3389/fddev.2022.932576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15316, KAKENHI-PROJECT-21H02651
[Journal Article] MicroRNA-126 suppresses the invasion of trophoblast-model JEG-3 cells by targeting LIN28A2021
- Author(s)
  Pan Xiaole、Noguchi Saki、Ando Misuzu、Nishimura Tomohiro、Tomi Masatoshi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 545 Pages: 132-137
- DOI
  10.1016/j.bbrc.2021.01.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21489, KAKENHI-PROJECT-20K16056, KAKENHI-PROJECT-18H03183
[Journal Article] Fluorouracil uptake in triple‐negative breast cancer cells: Negligible contribution of equilibrative nucleoside transporters 1 and 22021
- Author(s)
  Noguchi Saki、Takagi Akinori、Tanaka Takahiro、Takahashi Yu、Pan Xiaole、Kibayashi Yuka、Mizokami Ryo、Nishimura Tomohiro、Tomi Masatoshi
- Journal Title
  
  Biopharmaceutics & Drug Disposition
  
  Volume: 42 Issue: 2-3 Pages: 85-93
- DOI
  10.1002/bdd.2261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16056, KAKENHI-PROJECT-18H03183, KAKENHI-PROJECT-20K21489
[Journal Article] Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction2020
- Author(s)
  Inagaki Mai、Nishimura Tomohiro、Nakanishi Takeo、Shimada Hiroaki、Noguchi Saki、Akanuma Shin-ichi、Tachikawa Masanori、Hosoya Ken-ichi、Tamai Ikumi、Nakashima Emi、Tomi Masatoshi
- Journal Title
  
  iScience
  
  Volume: 23 Issue: 5 Pages: 101098-101098
- DOI
  10.1016/j.isci.2020.101098
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18J12895, KAKENHI-PROJECT-20K16056, KAKENHI-PROJECT-18H03183
[Journal Article] Quantification of ENT1 and ENT2 Proteins at the Placental Barrier and Contribution of These Transporters to Ribavirin Uptake.2019
- Author(s)
  Nishimura T, Sano Y, Takahashi Y, Noguchi S, Uchida Y, Takagi A, Tanaka T, Katakura S, Nakashima E, Tachikawa M, Maruyama T, Terasaki T, Tomi M.
- Journal Title
  
  J Pharm Sci.
  
  Volume: 108(12) Issue: 12 Pages: 3917-3922
- DOI
  10.1016/j.xphs.2019.09.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06900, KAKENHI-PUBLICLY-18H04534, KAKENHI-PROJECT-18H03183, KAKENHI-PROJECT-18K14926
[Journal Article] Hypotaurine is a substrate of GABA transporter family members GAT2/Slc6a13 and TAUT/Slc6a6.2018
- Author(s)
  Nishimura T, Higuchi K, Yoshida Y, Sugita-Fujisawa Yuki, Kojima K, Sugimoto M, Santo M, Tomi M, Nakashima E.
- Journal Title
  
  Biol Pharm Bull.
  
  Volume: in press
- NAID
  130007491801
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08595
[Journal Article] Cellular uptake of levocetirizine by Organic Anion Transporter 42017
- Author(s)
  Noguchi S, Nishimura T, Mukaida S, Benet LZ, Nakashima E, Tomi M
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 印刷中 Issue: 9 Pages: 2895-2898
- DOI
  10.1016/j.xphs.2017.03.026
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16J05272, KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K15007, KAKENHI-PROJECT-15K08595
[Journal Article] Contributions of system A subtypes to α-methylaminoisobutyric acid uptake by placental microvillous membranes of human and rat.2017
- Author(s)
  Takahashi Y, Nishimura T, Maruyama T, Tomi M, Nakashima E
- Journal Title
  
  Amino Acids.
  
  Volume: 49 Issue: 4 Pages: 795-803
- DOI
  10.1007/s00726-017-2384-7
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05474, KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K15007, KAKENHI-PROJECT-15K15610, KAKENHI-PROJECT-16K11109, KAKENHI-PROJECT-17K19731
[Journal Article] Contribution of equilibrative nucleoside transporter (ENT) 2 to fluorouracil transport in rat placental trophoblast cells2017
- Author(s)
  A. Takagi, T. Nishimura, T. Akashi, M. Tomi, E. Nakashima
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 32 Issue: 2 Pages: 151-156
- DOI
  10.1016/j.dmpk.2016.12.001
- NAID
  210000176253
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K15007
[Journal Article] Co-localization of microsomal prostaglandin E synthase-1 with cyclooxygenase-1 in layer II of murine placental syncytiotrophoblasts2017
- Author(s)
  M. Inagaki, T. Nishimura, S. Akanuma, T. Nakanishi, M. Tachikawa, I. Tamai, K. Hosoya, E. Nakashima, M. Tomi
- Journal Title
  
  Placenta
  
  Volume: 53 Pages: 76-82
- DOI
  10.1016/j.placenta.2017.04.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K15007, KAKENHI-PROJECT-15K08595
[Journal Article] Layer II of placental syncytiotrophoblasts expresses MDR1 and BCRP at the apical membrane in rodents2016
- Author(s)
  T. Akashi, T. Nishimura, Y. Takaki, M. Takahashi, B.C. Shin, M. Tomi, E. Nakashima
- Journal Title
  
  Reprod. Toxicol.
  
  Volume: 65 Pages: 375-381
- DOI
  10.1016/j.reprotox.2016.09.002
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K15007, KAKENHI-PROJECT-15K08595
[Journal Article] 胎児移行性の低い薬物について教えてください2016
- Author(s)
  登美斉俊
- Journal Title
  
  月刊薬事
  
  Volume: 58 Pages: 666-669
- Data Source
  KAKENHI-PROJECT-26282028
[Journal Article] Organic anion transporter 4-mediated transport of olmesartan at basal plasma membrane of human placental barrier2015
- Author(s)
  Noguchi S, Nishimura T, Fujibayashi A, Maruyama T, Tomi M, Nakashima E.
- Journal Title
  
  J Pharm Sci
  
  Volume: 104 Issue: 9 Pages: 3128-3135
- DOI
  10.1002/jps.24434
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560063, KAKENHI-PROJECT-25860396, KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K08595
[Journal Article] Role of OAT4 in uptake of estriol precursor 16α-hydroxy dehydroepiandrosterone sulfate into human placental syncytiotrophoblasts from fetus.2015
- Author(s)
  Tomi M, Eguchi H, Ozaki M, Tawara T, Nishimura S, Higuchi K, Maruyama T, Nishimura T, Nakashima E.
- Journal Title
  
  Endocrinol
  
  Volume: 156 Issue: 7 Pages: 2704-2712
- DOI
  10.1210/en.2015-1130
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K08595, KAKENHI-PROJECT-26282028
[Journal Article] Protective effect of hypotaurine against oxidative stress-induced cytotoxicity in rat placental trophoblasts2015
- Author(s)
  Nishimura T, Duereh M, Sugita Y, Yoshida Y, Higuchi K, Tomi M, Nakashima E.
- Journal Title
  
  Placenta
  
  Volume: 36 Issue: 6 Pages: 693-698
- DOI
  10.1016/j.placenta.2015.02.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560063, KAKENHI-PROJECT-25860396, KAKENHI-PROJECT-26282028, KAKENHI-PROJECT-15K08595
[Journal Article] Role of protein kinase A in regulating steroid sulfate uptake for estrogen production in human placental choriocarcinoma cells2014
- Author(s)
  Tomi M, Miyata Y, Noguchi S, Nishimura S, Nishimura T, Nakashima E.
- Journal Title
  
  Placenta
  
  Volume: 35 Issue: 8 Pages: 658-660
- DOI
  10.1016/j.placenta.2014.06.003
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25560063, KAKENHI-PROJECT-25860396
[Journal Article] System amino acid transporter SNAT2 shows subtype-specific affinity for betaine and hyperosmotic inducibility in placental trophoblasts.2014
- Author(s)
  Nishimura T, Yagi R, Usuda M, Oda K, Yamazaki M, Suda S, Takahashi Y, Okazaki F, Sai Y, Higuchi, K, Maruyama T, Tomi M, Nakashima E
- Journal Title
  
  Biochim Biophys Acta.
  
  Volume: VOL. 1838 Issue: 5 Pages: 1306-12
- DOI
  10.1016/j.bbamem.2014.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249076, KAKENHI-PROJECT-24390381, KAKENHI-PROJECT-24790171, KAKENHI-PROJECT-25462574, KAKENHI-PROJECT-25560063, KAKENHI-PROJECT-25670706, KAKENHI-PROJECT-25860396
[Journal Article] Estrogen receptor α induction by mitoxantrone increases Abcg2 expression in placental trophoblast cells.2013
- Author(s)
  Oda K, Nishimura T, Higuchi K, Ishido N, Ochi K, Iizasa H, Sai Y, Tomi M, Nakashima E.
- Journal Title
  
  J Pharm Sci
  
  Volume: 102 Issue: 9 Pages: 3364-3372
- DOI
  10.1002/jps.23549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590443, KAKENHI-PROJECT-23790199, KAKENHI-PROJECT-24790171, KAKENHI-PROJECT-25860396
[Journal Article] Mechanism of Nucleoside Uptake in Rat Placenta and Induction of Placental CNT2 in Experimental Diabetes2012
- Author(s)
  Nishimura T, Chishu T, Tomi M, Nakamura R, Sato K, Kose N, Sai Y, Nakashima E
- Journal Title
  
  Drug Metabolism and Pharmacokinetics
  
  Volume: 27 Issue: 4 Pages: 439-446
- DOI
  10.2133/dmpk.DMPK-11-RG-103
- NAID
  130004463266
- ISSN
  1347-4367, 1880-0920
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790171, KAKENHI-PROJECT-23790199
[Journal Article] Mother-to-fetus transfer of antiviral drugs and the involvement of transporters at the placental barrier2011
- Author(s)
  Tomi M, Nishimura T, Nakashima E.
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Issue: 9 Pages: 3708-3718
- DOI
  10.1002/jps.22642
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590175, KAKENHI-PROJECT-22790171, KAKENHI-PROJECT-23790199
[Journal Article] Enhancement of zidovudine transfer to molt-4 cells, a human t-cell model, by dehydroepiandrosterone sulfate2011
- Author(s)
  Nishimura T, Tanaka J, Tomi M, Seki Y, Kose N, Sai Y, Nakashima E.
- Journal Title
  
  J Pharm Sci
  
  Volume: 100 Issue: 9 Pages: 3959-3967
- DOI
  10.1002/jps.22624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590175, KAKENHI-PROJECT-22790171, KAKENHI-PROJECT-23590173, KAKENHI-PROJECT-23790199, KAKENHI-PROJECT-23790606
[Journal Article] Strategies for therapy of retinal diseases using systemic drug delivery: relevance of transporters at the blood-retinal barrier2011
- Author(s)
  Hosoya K, Tomi M, Tachikawa M
- Journal Title
  
  Expert Opin Drug Deliv
  
  Volume: 8(12) Issue: 12 Pages: 1571-1587
- DOI
  10.1517/17425247.2011.628983
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790199
[Journal Article] Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress.2010
- Author(s)
  Nishimura T, Sai Y, Fujii J, Muta M, Iizasa H, Tomi M, Deureh M, Kose N, Nakashima E.
- Journal Title
  
  Placenta
  
  Volume: 31 Pages: 1003-1009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590175
[Journal Article] Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress.2010
- Author(s)
  Nishimura T, Sai Y, Fujii J, Muta M, Iizasa H, Tomi M, Deureh M, Kose N, Nakashima E.
- Journal Title
  
  Placenta
  
  Volume: 31 Pages: 1003-1009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] The role of blood-ocular barrier transporters in retinal drug disposition: an overview2010
- Author(s)
  M.Tomi, K.Hosoya
- Journal Title
  
  Expert Opin.Drug Metab.Toxicol. 6
  
  Pages: 1111-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Proton-coupled erythromycin antiport at rat blood-placenta barrier.2010
- Author(s)
  Sai Y, Nishimura T, Ochi K, Tanaka N, Takagi A, Tomi M, Kose N, Kobayashi Y, Miyakoshi N, Kitagaki S, Mukai C, Nakashima E.
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 38 Pages: 1576-1581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590175
[Journal Article] Involvement of OCTN2 in the transport of acetyl-Lcarnitine across the inner blood-retinal barrier2010
- Author(s)
  M.Tachikawa, Y.Takeda, M.Tomi, K.Hosoya
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci. 51
  
  Pages: 430-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] The role of blood-ocular barrier transporters in retinal drug disposition : an overview.2010
- Author(s)
  Tomi M, Hosoya K.
- Journal Title
  
  Expert Opin.Drug Metab.Toxicol.
  
  Volume: 6 Pages: 1111-1124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Proton-coupled erythromycin antiport at rat blood-placenta barrier2010
- Author(s)
  Y.Sai, T.Nishimura, K.Ochi, N.Tanaka, A.Takagi, M.Tomi, N.Kose, Y.Kobayashi, N.Miyakoshi, S.Kitagaki, C.Mukai, E.Nakashima
- Journal Title
  
  Drug Metab.Dispos. 38
  
  Pages: 1576-1581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Proton-coupled erythromycin antiport at rat blood-placenta barrier2010
- Author(s)
  Sai Y, Nishimura T, Ochi K, Tanaka N, Takagi A, Tomi M, Kose N, Kobayashi Y, Miyakoshi N, Kitagaki S, Mukai C, Nakashima E.
- Journal Title
  
  Drug Metab Dispos.
  
  Volume: 38 Issue: 9 Pages: 1576-1581
- DOI
  10.1124/dmd.110.033266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590175
[Journal Article] Proton-coupled erythromycin antiport at rat blood-placenta barrier.2010
- Author(s)
  Sai Y, Nishimura T, Ochi K, Tanaka N, Takagi A, Tomi M, Kose N, Kobayashi Y, Miyakoshi N, Kitagaki S, Mukai C, Nakashima E.
- Journal Title
  
  Drug Metab Dispos
  
  Volume: 38 Pages: 1576-1581
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Involvement of OCTN2 in the transport of acetyl-L-carnitine across the inner blood-retinal barrier2010
- Author(s)
  Tachikawa M, Takeda Y, Tomi M, Hosoya K.
- Journal Title
  
  Invest Ophthalmol Vis Sci 51(1)
  
  Pages: 430-436
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress2010
- Author(s)
  T.Nishimura, Y.Sai, J.Fujii, M.Muta, H.Iizasa, M.Tomi, M.Deureh, N.Kose, E.Nakashima
- Journal Title
  
  Placenta 31
  
  Pages: 1003-1009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Roles of TauT and system A in cytoprotection of rat syncytiotrophoblast cell line exposed to hypertonic stress2010
- Author(s)
  Nishimura T, Sai Y, Fujii J, Muta M, Iizasa H, Tomi M, Deureh M, Kose N, Nakashima E.
- Journal Title
  
  Placenta
  
  Volume: 31 Pages: 1003-1009
- URL
  http://dx.doi.org/10.1016/j.placenta.2010.08.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590175
[Journal Article] Cationic amino acid transporter 1-mediated L-arginine transport at the inner blood-retinal barrier2009
- Author(s)
  Tomi M, Kitade N, Hirose S, Yokota N, Akanuma S, Tachikawa M, Hosoya K.
- Journal Title
  
  J Neurochem 111(3)
  
  Pages: 716-725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] Cationic amino acid transporter 1 (CAT1)-mediated L-arginine transport at the inner blood-retinal barrier2009
- Author(s)
  M.Tomi, N.Kitade, S.Hirose, N.Yokota, S.Akanuma, M.Tachikawa, K.Hosoya
- Journal Title
  
  J.Neurochem. 111
  
  Pages: 716-725
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890246
[Journal Article] L-Type amino acid transporter 1 (LAT1)-mediated L-leucine transport at the inner blood-retinal barrier2005
- Author(s)
  M.Tomi
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci. 46
  
  Pages: 2522-2530
- Data Source
  KAKENHI-PROJECT-17790116
[Journal Article] Advances in the cell biology of transport via the inner blood-retinal barrier : establishment of cell lines and transport functions2005
- Author(s)
  K.Hosoya, M.Tomi
- Journal Title
  
  Biol.Pharm.Bull. 28
  
  Pages: 1-8
- NAID
  10016658293
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Retinal selectivity of gene expression in rat retinal versus brain capillary endothelial cell lines by differential display analysis2004
- Author(s)
  T.Tomi
- Journal Title
  
  Mol. Vis. 10
  
  Pages: 537-543
- Data Source
  KAKENHI-PROJECT-15659034
[Journal Article] Blood-to-retina transport of creatine via creatine transporter (CRT) at the rat inner blood-retinal barrier2004
- Author(s)
  T.Nakashima, M.Tomi, K.Katayama, M.Tachikawa, M.Watanabe, T.Terasaki, K.Hosoya
- Journal Title
  
  J.Neurochem. 89
  
  Pages: 1454-1461
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Application of magnetically isolated rat retinal vascular endothelial cells for the determination of transporter gene expression levels at the inner blood-retinal barrier2004
- Author(s)
  T.Tomi
- Journal Title
  
  J.Neurochem. 91
  
  Pages: 1244-1248
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Application of magnetically isolated rat retinal vascular endothelial cells for the determination of transporter gene expression levels at the inner blood-retinal barrier2004
- Author(s)
  M.Tomi, K.Hosoya
- Journal Title
  
  J.Neurochem. 91
  
  Pages: 1244-1248
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Application of magnetically isolated rat retinal vascular endothelial cells for the determination of transporter gene expression levels at the inner blood-retinal barrier2004
- Author(s)
  T.Tomi
- Journal Title
  
  J. Neurochem. 91
  
  Pages: 1244-1248
- Data Source
  KAKENHI-PROJECT-15659034
[Journal Article] Vitamin C transport in oxidized form across the rat blood-retinal barrier2004
- Author(s)
  K.Hosoya, A.Minamizono, K.Katayama, T.Terasaki, M.Tomi
- Journal Title
  
  Invest.Ophthalmol.Vis.Sci. 45
  
  Pages: 1232-1239
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Expression and regulation of L-cystine transporter, system x^-_c, in the newly developed rat retinal Muller cell line (TR-MUL)2003
- Author(s)
  M.Tomi
- Journal Title
  
  Glia 43
  
  Pages: 208-217
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Establishment of conditionally immortalized rat retinal pericyte cell lines (TR-rPCT) and their application in a co-culture system using retinal capillary endothelial cell line (TR-iBRB2)2003
- Author(s)
  T.Kondo, K.Hosoya, S.Hori, M.Tomi, S.Ohtsuki, H.Takanaga, E.Nakashima, H.Iizasa, T.Asashima, M.Ueda, M.Obinata, T.Terasaki
- Journal Title
  
  Cell Struct.Funct. 28
  
  Pages: 145-153
- NAID
  10011619370
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Journal Article] Expression and regulation of L-cystine transporter, system x_c, in the newly developed rat retinal Muller cell line (TR-MUL)2003
- Author(s)
  M.Tomi, T.Funaki, H.Abukawa, K.Katayama, T.Kondo, S.Ohtsuki, M.Ueda, M.Obinata, T.Terasaki, K.Hosoya
- Journal Title
  
  Glia 43
  
  Pages: 208-217
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15390046
[Presentation] 胎盤関門における動物種差と胎児移行に及ぼす影響2024
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  日本薬学会第144年会(横浜)
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Ezrin遺伝子欠損に伴う胎仔発育不全と胎盤免疫寛容の機能低下の関連解析2024
- Author(s)
  山中真悠子, 西村友宏, 溝上遼, 野口幸希, 登美斉俊
- Organizer
  日本薬学会第144年会(横浜)
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] 薬物の胎盤透過を規定するメカニズムと薬物選択2024
- Author(s)
  登美斉俊, 野口幸希,千葉康司,西村友宏.
- Organizer
  第17回日本性差医学・医療学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] マウス胎盤におけるMFSD2Aの発現とlysophosphatidylcholine結合型docosahexaenoic acid透過に与える影響2023
- Author(s)
  登美斉俊, 野口幸希, 関瑞生, 関誠悟, 山本元輝, 定村龍太, 赤沼伸乙, 河野早弥賀, 盛武浩, 細谷健一, 西村友宏.
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] ラット胎盤における薬物輸送体MATE1の発現が胎盤透過の動物種差に及ぼす影響2023
- Author(s)
  鈴木あしゅかん, 山内青依, 橋本理梨佳, 野口幸希, 西村友宏, 登美斉俊.
- Organizer
  第63回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Effect of species differences in expression of placental MATE1 on fetal transfer of organic cations.2023
- Author(s)
  Sakamoto R, Suzuki A, Yamauchi A, Sakai M, Hashimoto R, Noguchi S, Nishimura T, Tomi M.
- Organizer
  2023 International Joint Meeting of the 23rd International Conference on Cytochrome P450 and the 38th Annual Meeting of the Japanese Society for the Study of Xenobiotics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] ヒト血管内皮細胞HUEhT-1による絨毛外栄養膜細胞HTR-8/SVneoの浸潤誘導2023
- Author(s)
  田島幸佳, 西村友宏, 野口幸希, 登美斉俊
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Prediction of Fetal Drug Exposure by integrating in vitro, in vivo, ex vivo, and in silico approaches.2023
- Author(s)
  Tomi M.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2023
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Attenuation of murine placental MDR1 and BCRP functions by their unique protein localization.2023
- Author(s)
  Tomi M, Fujita A, Noguchi S, Nishimura T.
- Organizer
  International Federation of Placenta Associations Meeting 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] 胎盤MATE1がMPP+の胎児移行性種差に与える影響2023
- Author(s)
  鈴木あしゅかん, 山内青依, 野口幸希, 橋本理梨佳, 西村友宏, 登美斉俊.
- Organizer
  日本薬剤学会第38年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Transport mechanism of propionic acid in human choriocarcinoma JEG-3 cells.2023
- Author(s)
  Kasuya A, Noguchi S, Nishimura T, Tomi M.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] ラット妊娠前のestrogen 作用不全が妊娠後期の血圧および胎仔成長に与える影響2022
- Author(s)
  原田裕香子, 西村友宏, 野口幸希, 登美斉俊
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] マウス胎盤関門と血液脳関門の組織薬物分布抑制におけるMDR1寄与比較2022
- Author(s)
  藤田有美, 濱田リカ, 井上慧子, 野口幸希, 嶋田努, 崔吉道, 西村友宏, 登美斉俊
- Organizer
  日本薬剤学会第37年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] 齧歯類における組織薬物分布に対するBCRP寄与の胎盤関門と血液脳関門の比較2022
- Author(s)
  藤田有美, 濱田リカ, 井上慧子, 野口幸希, 嶋田努, 崔吉道, 西村友宏, 登美斉俊
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] 単一細胞遺伝子発現解析に基づくマウス栄養膜幹細胞から分化する細胞集団の分布2022
- Author(s)
  石鍋巧朗, 野口幸希, 菅沼名津季, 西村友宏, 登美斉俊
- Organizer
  第30回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] マウス胎盤OCTN1がエルゴチオネインの胎児移行に果たす役割2022
- Author(s)
  中村綾音, 西村友宏, 石本尚大, 野口幸希, 加藤将夫, 登美斉俊
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] マウス胎盤におけるPGE2受容体サブタイプの発現評価2022
- Author(s)
  高橋駿太, 稲垣舞, 野口幸希, 西村友宏, 登美斉俊
- Organizer
  第66回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] ラット胎盤におけるOatp1a5, 2b1, 4a1のmRNA発現とイルベサルタンおよびオルメサルタンに対する取り込み活性の評価2022
- Author(s)
  織井啓介, 西村友宏, 野口幸希, 登美斉俊
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] 薬物の胎盤透過を規定するメカニズムと薬物選択2022
- Author(s)
  登美斉俊
- Organizer
  第8回日本医薬品安全性学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] アンジオテンシンⅡ受容体拮抗薬 (ARBs) の経細胞輸送におけるOAT4の役割2022
- Author(s)
  榊原早織, 野口幸希, 平原優有, 舟橋和毅, 加島里菜, 西村友宏, 登美斉俊
- Organizer
  日本薬物動態学会第37回年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] マウス胎盤におけるPGE2受容体の発現解析2021
- Author(s)
  高橋駿太, 稲垣舞, 野口幸希, 西村友宏, 登美斉俊
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] LIN28A発現抑制を介したmiR-126によるJEG-3細胞の浸潤抑制2021
- Author(s)
  野口幸希, 潘暁楽, 安藤美鈴, 西村友宏, 登美斉俊
- Organizer
  第29回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] ダントロレンの胎盤透過に及ぼす排出輸送体の影響評価2021
- Author(s)
  濱田リカ, 植田有美, 野口幸希, 西村友宏, 登美斉俊
- Organizer
  第61回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] The comparison of the MDR1 contribution to the drug distribution of the placental barrier and blood-brain barrier2021
- Author(s)
  Fujita A, Hamada R, Inoue S, Noguchi S, Shimada T, Sai Y, Nishimura T, Tomi M
- Organizer
  第15回次世代を担う若手医療薬科学シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] ヒト胎盤透過性の定量予測に向けたアプローチ2021
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  第61回日本先天異常学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] メトホルミンのマウス胎盤透過に寄与する輸送体の検討2021
- Author(s)
  坂井真衣子, 中口佳美, 西村友宏, 野口幸希, 石本尚大, 加藤将夫, 登美斉俊
- Organizer
  第61回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Effect of maternofetal albumin concentration gradient on species differences in fetal drug transfer2021
- Author(s)
  Tomi M, Nomura T, Noguchi S, Nishimura T
- Organizer
  International Federation of Placenta Associations (IFPA) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Placental control of fetal drug transfer2021
- Author(s)
  Tomi M
- Organizer
  The 1st International Conference on Pharmaceutical Sciences and Military Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] マウス胎盤関門と血液脳関門のMDR1関門透過制御寄与の比較2021
- Author(s)
  藤田有美, 濱田リカ, 井上慧子, 野口幸希, 嶋田努, 崔吉道, 西村友宏, 登美斉俊
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Ex vivoヒト胎盤灌流試験を用いたジゴキシンのヒト胎盤薬物動態モデル2021
- Author(s)
  黒沢健, 千葉康司, 野口幸希, 西村友宏, 登美斉俊
- Organizer
  日本薬物動態学会第36回年会
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] ヒト胎盤透過性の定量予測に向けたアプローチ2021
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  第61回日本先天異常学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Placental control of fetal drug transfer2021
- Author(s)
  Tomi M
- Organizer
  The 1st International Conference on Pharmaceutical Sciences and Military Pharmacy
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02651
[Presentation] Effect of maternofetal albumin concentration gradient on species differences in fetal drug transfer2021
- Author(s)
  Tomi M, Nomura T, Noguchi S, Nishimura T
- Organizer
  International Federation of Placenta Associations (IFPA) 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] マウス胎盤におけるオメガ3脂肪酸輸送体Mfsd2aの発現解析2021
- Author(s)
  関誠悟, 山本元輝, 赤沼伸乙, 定村龍太, 野口幸希, 河野早弥賀, 盛武浩, 細谷健一, 西村友宏, 登美斉俊
- Organizer
  第45回日本女性栄養・代謝学会学術集会・第10回日本DOHaD学会学術集会
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] 関門としての胎盤：薬物透過制御機構とその種差2020
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  第47回日本毒性学会学術年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] 関門としての胎盤：薬物透過制御機構とその種差2020
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  第47回日本毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] 薬物の胎盤透過を規定するメカニズムとその影響2020
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  第60回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] 薬物の胎盤透過を規定するメカニズムとその影響2020
- Author(s)
  登美斉俊, 野口幸希, 西村友宏
- Organizer
  第60回日本先天異常学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K21489
[Presentation] プレガバリンのラット脳移行における血漿中LAT1基質アミノ酸の影響2020
- Author(s)
  野口幸希, 高橋優, 西村友宏, 登美斉俊
- Organizer
  第15回トランスポーター研究会年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] 血漿タンパク結合率が薬物胎児移行性の種差に及ぼす影響2019
- Author(s)
  野村岳広、野口幸希、西村友宏、登美斉俊
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] 胎児/母体血漿中非結合形濃度比を用いたdigoxinのラット胎盤透過性評価2019
- Author(s)
  野村岳広、西村友宏、野口幸希、登美斉俊
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] マウス栄養膜幹細胞3次元培養系における関門機能分子の発現誘導2019
- Author(s)
  木林由佳、野口幸希、田辺美那子、齋藤義正、西村友宏、登美斉俊
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] ヒト栄養膜由来JEG-3細胞の分化過程におけるmiR-126の役割2019
- Author(s)
  潘曉楽、野口幸希、安藤美鈴、竹村千尋、西村友宏、登美斉俊
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] miR-126が栄養膜モデルJEG-3細胞における合胞体化促進因子の発現に与える影響2019
- Author(s)
  潘曉楽、野口幸希、安藤美鈴、竹村千尋、西村友宏、登美斉俊
- Organizer
  日本薬剤学会第34年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] Possibilities and limitations of extrapolating fetal drug transfer data from rodents to human pregnancy2019
- Author(s)
  Tomi Masatoshi、Noguchi Saki、Nishimura Tomohiro
- Organizer
  Asian Federation for Pharmaceutical Sciences (AFPS) 2019 Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] OAT4を介したlosartan carboxylic acidおよびcandesartanのCl-依存性輸送2019
- Author(s)
  飛田萌子、野口幸希、木村りか、福本文香、西村友宏、登美斉俊
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] マウス栄養膜幹細胞の分化に伴うOATP2A1発現変動とHIF1αの影響2019
- Author(s)
  井坂真実、西村友宏、稲垣舞、田辺美那子、野口幸希、登美斉俊
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] マウス栄養膜幹細胞3次元培養系における関門機能分子の発現誘導2019
- Author(s)
  木林由佳、野口幸希、田辺美那子、齋藤義正、西村友宏、登美斉俊
- Organizer
  日本薬物動態学会第34回年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] Induction mechanism of MDR1 in mouse trophoblast stem cell differentiation2018
- Author(s)
  Tanabe M, Noguchi S, Nishimura T, Tomi M
- Organizer
  International Federation of Placenta Associations (IFPA) 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] 血液脳関門における中性アミノ酸トランスポーターLAT1 を介したpregabalin輸送2018
- Author(s)
  "高橋優、西村友宏、樋口慧、野口幸希、手賀悠真、黒澤俊樹、出口芳春、登美斉俊"
- Organizer
  第40回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] The physiological and pharmacological roles of organic anion transporter 4 in the placenta2018
- Author(s)
  Tomi M
- Organizer
  International Federation of Placenta Associations (IFPA) 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] LAT1 が血液脳関門におけるpregabalin 輸送に果たす役割2018
- Author(s)
  髙橋優、西村友宏、樋口慧、野口幸希、手賀悠真、黒澤俊樹、出口芳春、登美斉俊
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-18H03183
[Presentation] 胎盤を介した胎児からのクレアチニン排出輸送機構の解析2017
- Author(s)
  山下稔貴、西村友宏、中島恵美、登美斉俊
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K15007
[Presentation] 浸透圧誘導性SNAT2発現に関与する3’非翻訳領域の同定2017
- Author(s)
  吉田啓佑、西村友宏、野口幸希、中島恵美、登美斉俊
- Organizer
  第61回日本薬学会関東支部会
- Data Source
  KAKENHI-PROJECT-15K08595
[Presentation] Hypotaurineおよびその供給因子の胎盤組織内分布2017
- Author(s)
  斉藤慶、西村友宏、中島恵美、登美斉俊
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K15007
[Presentation] Role of organic anion transporter 4 on the transport of olmesartan across the basal plasma membrane of human placental syncytiotrophoblast2016
- Author(s)
  Tomi M, Noguchi S, Fujibayashi A, Maruyama T, Nakashima E, Nishimura T
- Organizer
  International Federation of Placenta Associations(IFPA) 2016
- Place of Presentation
  Portland（米国）
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] SNAT1 predominantly contributes to system A function in placental microvillous membranes2016
- Author(s)
  Takahashi Y, Nishimura T, Maruyama T, Nakashima E, Tomi M
- Organizer
  International Federation of Placenta Associations(IFPA) 2016
- Place of Presentation
  Portland（米国）
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] マウス胎盤内プロスタグランジンPGE2 分解に果たす輸送体の役割2016
- Author(s)
  稲垣舞、西村友宏、中西猛夫、島田紘明、赤沼伸乙、立川正憲、細谷健一、玉井郁巳、中島恵美、登美斉俊
- Organizer
  日本薬物動態学会第31年会
- Place of Presentation
  キッセイ文化ホール（長野県松本市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] ヒト有機アニオントランスポーターOAT4を介したセチリジン輸送2016
- Author(s)
  登美斉俊、野口幸希、向田紗也、西村友宏、中島恵美
- Organizer
  日本薬剤学会第31年会
- Place of Presentation
  長良川国際会議場（岐阜県岐阜市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] Expression and function of prostaglandin transporter in the murine placenta2016
- Author(s)
  Inagaki M, Nishimura T, Nakanishi T, Akanuma S, Tachikawa M, Tamai I, Hosoya K, Nakashima E, Tomi M
- Organizer
  International Federation of Placenta Associations(IFPA) 2016
- Place of Presentation
  Portland, USA
- Year and Date
  2016-09-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] Acute Induction of sodium-dependent neutral amino acid transporter 2 (SNAT2) expression by hyperosmotic condition in placental syncytiotrophoblasts2016
- Author(s)
  Tomohiro Nishimura, Keisuke Yoshida, Yu Takahashi, Masatoshi Tomi, Emi Nakashima
- Organizer
  11th　International ISSX　Meeging
- Place of Presentation
  Busan Convention and Exhibition Center (Korea, Busan)
- Year and Date
  2016-06-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08595
[Presentation] げっ歯類合胞体栄養膜細胞層におけるMDR1およびBCRPの局在2016
- Author(s)
  登美斉俊、明石知也、高木良也、中島恵美、西村友宏
- Organizer
  第24回日本胎盤学会学術集会
- Place of Presentation
  ホテルアバローム紀の国（和歌山県和歌山市）
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] SLC6Aファミリーによるヒポタウリン輸送と酸化ストレスに対する細胞保護作用2016
- Author(s)
  西村友宏、樋口慧、中島恵美、登美斉俊
- Organizer
  第38回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  名古屋市立大学大学院薬学研究科（愛知県名古屋市）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-15K15007
[Presentation] Induction Mechanism of Sodium-dependent Amino Acid Transporter2(SNAT2)in Rat Placental Trophoblasts2016
- Author(s)
  Tomohiro Nishimura, Emi Nakashima, Masatoshi Tomi
- Organizer
  The 1st workshop for Japan-Korea Young Scientists on Pharmaceutics
- Place of Presentation
  Kyoto Kyoiku Bunka Center (Kyoto, Kyoto)
- Year and Date
  2016-06-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08595
[Presentation] ヒトOAT4 (SLC22A11) 遺伝子の胎盤特異的転写開始点の同定と転写活性に及ぼす影響2016
- Author(s)
  古郡加奈子、野口幸希、篠原裕美、阿部真希子、西村友宏、中島恵美、登美斉俊
- Organizer
  日本薬物動態学会第31年会
- Place of Presentation
  キッセイ文化ホール（長野県松本市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] ヒト胎盤関門有機アニオントランスポーターが薬物胎児移行性に与える影響2015
- Author(s)
  野口幸希, 西村友宏, 登美斉俊, 中島恵美.
- Organizer
  日本薬物動態学会第30回年会
- Place of Presentation
  タワーホール船堀（東京都江戸川区）
- Year and Date
  2015-11-12
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] 胎盤trophoblast におけるSNAT2 の高浸透圧刺激による急速発現調節2015
- Author(s)
  西村友宏、小澤夏美、高橋優、登美斉俊、中島恵美
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール（長崎県・長崎市）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K08595
[Presentation] 関門トランスポーターによる薬物組織分布制御機構の研究2015
- Author(s)
  登美斉俊
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市）
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-15K15007
[Presentation] Syncytiotrophoblast layer 2 expresses MDR1 and BCRP efflux transporters in rodent placenta.2015
- Author(s)
  Tomi M, Akashi T, Takaki Y, Nishimura T, Nakashima E.
- Organizer
  International Federation of Placenta Associations 2015
- Place of Presentation
  Brisbane (Australia)
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15007
[Presentation] Evaluation of materno-fetal permeability of various compounds by fetus uptake index (FUI) method2015
- Author(s)
  Akashi T, Nishimura T, Asada T, Ozawa H, Sano Y, Katsube A, Tomi M, Nakashima E.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2015
- Place of Presentation
  Bangkok (Thailand)
- Year and Date
  2015-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] Induction of sodium-dependent neutral amino acid transporter 2 (SNAT2) by hypertonic stress in placental syncytiotrophoblasts2015
- Author(s)
  Nishimura T, Kojima T, Takahashi Y, Tomi M, Nakashima E.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2015
- Place of Presentation
  Bangkok (Thailand)
- Year and Date
  2015-11-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08595
[Presentation] げっ歯類胎盤関門におけるMDR1およびBCRPの局在とヒトとの種差2015
- Author(s)
  明石知也, 西村友宏, 高木良也, 登美斉俊, 中島恵美.
- Organizer
  第10回トランスポーター研究会年会
- Place of Presentation
  慶應義塾大学薬学部（東京都港区）
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-15K15007
[Presentation] 関門トランスポーターによる薬物組織分布制御機構の研究2015
- Author(s)
  登美斉俊
- Organizer
  日本薬剤学会第30年会
- Place of Presentation
  長崎ブリックホール(長崎県長崎市）
- Year and Date
  2015-05-21
- Invited
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] 薬物胎児移行性の支配要因となるヒト胎盤トランスポーターの同定と定量評価2014
- Author(s)
  登美斉俊
- Organizer
  日本薬学会第134年会
- Place of Presentation
  熊本
- Invited
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] The impact of placental transporters in creating the dynamic maternal-fetal interface2013
- Author(s)
  Tomi M, Nishimura T, Nakashima E.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Jeju, Republic of Korea
- Invited
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] Fetus uptake index (FUI) 法を用いた水溶性生体内物質のラット胎盤関門透過性の評価.2013
- Author(s)
  登美斉俊、小澤英輝、佐野雄一朗、勝部彬、西村友宏、中島恵美
- Organizer
  第8回トランスポーター研究会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] System A amino acid transporter SNAT2 shows subtype-specific affinity for betaine.2013
- Author(s)
  Eguchi H, Nishimura T, Usuda M, Suda S, Tomi M, Nakashima E.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2013
- Place of Presentation
  Jeju, Republic of Korea
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] SNAT2-specific transport function of betaine among amino acid transport system A subtypes.2013
- Author(s)
  Eguchi H, Nishimura T, Usuda M, Suda S, Tomi M, Nakashima E.
- Organizer
  International Federation of Placenta Associations (IFPA) 2013
- Place of Presentation
  Whistler, Canada
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] 胎盤エストロゲン合成におけるorganic anion transporter (OAT) 4 の役割2012
- Author(s)
  西村祥香,西村友宏,樋口慧,登美斉俊,中島恵美 .
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Year and Date
  2012-03-31
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Role of anion transporters, IN:Workshop 11 “The role of human placenta in regulating fetal exposure to medications during pregnancy.2012
- Author(s)
  登美斉俊
- Organizer
  IFPA Meeting 2012
- Place of Presentation
  広島国際会議場（広島市）
- Invited
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Role of organic anion transporter (OAT) 4 on estriol synthesis in the placental syncytiotrophoblasts.2012
- Author(s)
  Tomi M, Ozaki M, Nishimura S, Higuchi K, Nishimura T, Nakashima E.
- Organizer
  IFPA Meeting 2012
- Place of Presentation
  広島国際会議場（広島市）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Role of anion transporters, IN:Workshop 11 "The role of human placenta in regulating fetal exposure to medications during pregnancy2012
- Author(s)
  Tomi M
- Organizer
  IFPA Meeting 2013
- Place of Presentation
  広島
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Role of OAT4 for supplying estriol precursor, 16α-hydroxy dehydroepiandrosterone sulfate, into the human placenta2012
- Author(s)
  Tomi M, Ozaki M, Nishimura S, Higuchi K, Nishimura T, Nakashima E
- Organizer
  International Symposium on Past, Present and Future of Molecular Pharmacokinetics
- Place of Presentation
  東京
- Year and Date
  2012-01-17
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] 医薬品の胎盤透過制御機構とその in vitro 評価2012
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  日本動物実験代替法学会第25回大会
- Place of Presentation
  東京
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Role of OAT4 for supplying estriol precursor, 16α-hydroxy dehydroepiandrosterone sulfate, into the human placenta.2012
- Author(s)
  Tomi M, Ozaki M, Nishimura S, Higuchi K, Nishimura T, Nakashima E.
- Organizer
  International Symposium on Past, Present and Future of Molecular Pharmacokinetics
- Place of Presentation
  一橋記念講堂（東京都）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] 医薬品の胎盤透過制御機構とそのin vitro評価2012
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  日本動物実験代替法学会第25回大会
- Place of Presentation
  慶應義塾大学（東京都）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Role of organic anion transporter (OAT) 4 on estriol synthesis in the placental syncytiotrophoblasts.2012
- Author(s)
  Tomi M, Ozaki M, Nishimura S, Higuchi K, Nishimura T, Nakashima E
- Organizer
  IFPA Meeting 2013
- Place of Presentation
  広島
- Year and Date
  2012-09-18
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] 胎盤エストロゲン合成におけるorganic anion transporter (OAT) 4 の役割.2012
- Author(s)
  西村祥香,西村友宏,樋口慧,登美斉俊,中島恵美.
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（北海道札幌市）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] ラット胎盤関門細胞株におけるMitoxantroneによるEstrogen Receptorを介したABCG2発現誘導2011
- Author(s)
  小田憲司、西村友宏、巨勢典子、登美斉俊、中島恵美
- Organizer
  第6回トランスポーター研究会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] OAT4を介したエストリオール前駆体16α-OH DHEAS輸送機構とその役割.2011
- Author(s)
  登美斉俊, 尾崎真由子, 西村友宏, 中島恵美.
- Organizer
  第6回トランスポーター研究会年会
- Place of Presentation
  東北大学（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] CD4陽性Tリンパ球モデルMolt-4細胞への抗ウイルス薬ジドブジン取り込み機構と標的化2011
- Author(s)
  西村友宏、田中純、登美斉俊、巨勢典子、中島恵美
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] 胎盤関門における OAT4 の生理的役割とその発現制御2011
- Author(s)
  登美斉俊、尾崎真由子、宮田優希、西村祥香、樋口慧、西村友宏、中島恵美
- Organizer
  第33回生体膜と薬物の相互作用シンポジウ
- Place of Presentation
  岡山
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] OAT4/SLC22A11-mediated uptake of 16α-hydroxydehydroepiandro- sterone sulfate at the placental barrier2011
- Author(s)
  Tomi M, Ozaki M, Higuchi K, Nishimura T, Nakashima E
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Kuala Lumpur, Malaysia
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] OAT4 を介したエストリオール前駆体16α-OH DHEAS 輸送機構とその役割2011
- Author(s)
  登美斉俊, 尾崎真由子, 西村友宏, 中島恵美
- Organizer
  第6回トランスポーター研究会年
- Place of Presentation
  仙台
- Year and Date
  2011-06-11
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] In vivo techniques for the evaluation of passages from Matamal and Fetal sides across the placental barrier2011
- Author(s)
  Asada T, Takanohashi T, Nishimura T, Tomi M, Nakashima E
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Kuala Lumpur Malaysia
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] In vivo techniques for the evaluation of passages from Matamal and Fetal sides across the placental bar2011
- Author(s)
  Asada T, Takanohashi T, Nishimura T, Tomi M, Nakashima E.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Kuala Lumpur Malaysia
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] 胎盤関門 OAT4 を介したエストリオール前駆体 16α-OH DHEAS 輸送機構2011
- Author(s)
  登美斉俊, 尾崎真由子, 西村友宏, 中島恵美
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Year and Date
  2011-05-31
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] 妊娠期低栄養が胎盤遺伝子発現に与える影響の解析2011
- Author(s)
  関口万智子,西村友宏,登美斉俊,中島恵美
- Organizer
  日本薬学会第131年会
- Place of Presentation
  静岡
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] 妊娠期低栄養が胎盤遺伝子発現に与える影響の解析2011
- Author(s)
  関口万智子, 西村友宏, 登美斉俊, 中島恵美
- Organizer
  日本薬剤学会第131年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] 胎盤関門におけるOAT4の生理的役割とその発現制御.2011
- Author(s)
  登美斉俊、尾崎真由子、宮田優希、西村祥香、樋口慧、西村友宏、中島恵美.
- Organizer
  第33回生体膜と薬物の相互作用シンポジウム
- Place of Presentation
  岡山大学（岡山県岡山市）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] ラット胎盤関門細胞株におけるMitoxantroneによるEstrogen Receptorを介したABCG2発現誘導2011
- Author(s)
  小田憲司、西村友宏、巨勢典子、登美斉俊、中島恵美
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] OAT4/SLC22A11-mediated uptake of 16α-hydroxydehydroepiandrosterone sulfate at the placental barrier.2011
- Author(s)
  Tomi M, Ozaki M, Higuchi K, Nishimura T, Nakashima E.
- Organizer
  Asian Federation for Pharmaceutical Sciences 2011
- Place of Presentation
  Renaissance Hotel Kuala Lumpur (Kuala Lumpur, Malaysia)
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] 胎盤関門OAT4を介したエストリオール前駆体16α-OH DHEAS輸送機構.2011
- Author(s)
  登美斉俊, 尾崎真由子, 西村友宏, 中島恵美.
- Organizer
  日本薬剤学会第26年会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-23790199
[Presentation] Up-regulation of organic anion transporter 4 (OAT4) by forskolin-induced differentiation in JEG-3 cells2010
- Author(s)
  M. Tomi, Y.Miyata, T.Nishimura, E.Nakashima
- Organizer
  Pharmaceutical Sciences World Congress 2010
- Place of Presentation
  New Orleans.
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] ヒト血液胎盤関門モデル細胞株における有機アニオントランスポーター(OAT4)の forskolin による発現誘導2010
- Author(s)
  宮田優希, 登美斉俊, 西村友宏, 中島恵美
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] ヒト血液胎盤関門の分化過程におけるOAT4発現誘導2010
- Author(s)
  登美斉俊,宮田優希,西村友宏,中島恵美
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Year and Date
  2010-05-12
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] 妊娠糖尿病モデルラット胎盤における核酸トランスポーターの発現変動2010
- Author(s)
  西村友宏、地主拓也、登美斉俊、巨勢典子、中島恵美
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] ラット胎盤関門におけるエリスロマイシンのプロトン共役排出輸送2010
- Author(s)
  崔吉道、西村友宏、越智香織、田中紀章、高木彰紀、登美斉俊、巨勢典子、中島恵美
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] Regulation of nucleoside transporters in the placenta of experimental diabetes2010
- Author(s)
  M. Tomi, T.Chishu, N.Kose, T.Nishimura, E.Nakashima
- Organizer
  日本薬物動態学会第25年会
- Place of Presentation
  さいたま
- Year and Date
  2010-10-08
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] ヒト血液胎盤関門モデル細胞株における有機アニオントランスポーター(OAT4)のforskolinによる発現誘導2010
- Author(s)
  宮田優希,登美斉俊,西村友宏,中島恵美
- Organizer
  日本薬学会第130年会
- Place of Presentation
  岡山
- Year and Date
  2010-03-28
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] ヒト血液胎盤関門organic anion transporter 4発現におけるcAMP/Protein kinase A経路の関与2010
- Author(s)
  登美斉俊,宮田優希,巨勢典子,西村友宏,中島恵美
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Year and Date
  2010-07-10
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] 胎盤hypotaurine取り込みにおけるGABAトランスポーター(Slc6a13)の関与2010
- Author(s)
  樋口慧、西村友宏、登美斉俊、巨勢典子、崔吉道、中島恵美
- Organizer
  第5回トランスポーター研究会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] Ezrin欠損マウス胎盤・胎児で減少するhypotaurineの胎盤におけるトランスポーター同定2010
- Author(s)
  樋口慧、西村友宏、登美斉俊、若山友彦、田村淳、月田早智子、曽我朋義、崔吉道、中島恵美
- Organizer
  日本薬剤学会第25年会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-21590175
[Presentation] 血液組織関門トランスポーターの発現と制御2010
- Author(s)
  登美斉俊
- Organizer
  第54回日本薬学会関東支部大会
- Place of Presentation
  東京
- Year and Date
  2010-10-02
- Data Source
  KAKENHI-PROJECT-21890246
[Presentation] Respective contribution system A subtypes to neutral amino acid transport at the placental microvillous membrane
- Author(s)
  Takahashi Y, Nishimura T, Suda S, Tomi M, Nakashima E.
- Organizer
  19th North American ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] Characterization of 16 α-hydroxy dehydroepiandrosterone sulfate transport in human placental basal plasma membrane vesicles.
- Author(s)
  Tomi M, Eguchi H, Nishimura T, Maruyama T, Nakashima E
- Organizer
  19th North American ISSX Meeting and 29th JSSX Annual Meeting
- Place of Presentation
  San Francisco
- Year and Date
  2014-10-19 – 2014-10-23
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] 有機アニオントランスポーターOAT4によるolmesartan輸送
- Author(s)
  野口幸希、登美斉俊、西村友宏、中島恵美
- Organizer
  第9回トランスポーター研究会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-14 – 2014-06-15
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] ヒト胎盤関門トランスポーターによる胎児防御機構と薬物輸送制御
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] 薬物胎児移行支配要因としての胎盤トランスポーター
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  医療薬学フォーラム2014・第22回クリニカルファーマシーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-28 – 2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] 胎盤刷子縁膜中性アミノ酸輸送におけるSystem Aサブタイプ別寄与率の評価
- Author(s)
  高橋優、西村友宏、須田沙也加、登美斉俊、中島恵美
- Organizer
  日本薬剤学会第29年会
- Place of Presentation
  大宮
- Year and Date
  2014-05-20 – 2014-05-22
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] Uptake mechanism of an estriol precursor, 16α-hydroxy dehydroepiandrosterone sulfate, at the basal plasma membrane of human term placenta
- Author(s)
  Tomi M, Eguchi H, Nishimura T, Maruyama T, Nakashima E.
- Organizer
  International Federation of Placenta Associations 2014
- Place of Presentation
  Paris
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] 薬物の胎児移行における胎盤トランスポーターのインパクト
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] 薬物胎児移行支配要因としての胎盤トランスポーター
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  医療薬学フォーラム2014・第22回クリニカルファーマシーシンポジウム
- Place of Presentation
  東京
- Year and Date
  2014-06-28 – 2014-06-29
- Invited
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] ヒト妊娠期エストリオール合成における胎盤基底細胞膜OAT4の関与
- Author(s)
  登美斉俊、江口拡美、丸山哲夫、西村友宏、中島恵美
- Organizer
  第9回トランスポーター研究会年会
- Place of Presentation
  名古屋
- Year and Date
  2014-06-14 – 2014-06-15
- Data Source
  KAKENHI-PROJECT-26282028
[Presentation] 薬物の胎児移行における胎盤トランスポーターのインパクト
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  第30回日本DDS学会学術集会
- Place of Presentation
  東京
- Year and Date
  2014-07-30 – 2014-07-31
- Invited
- Data Source
  KAKENHI-PROJECT-25560063
[Presentation] ヒト胎盤関門トランスポーターによる胎児防御機構と薬物輸送制御
- Author(s)
  登美斉俊、西村友宏、中島恵美
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸
- Year and Date
  2015-03-25 – 2015-03-28
- Invited
- Data Source
  KAKENHI-PROJECT-26282028
[]

1. NISHIMURA Tomohiro (40453518)

# of Collaborated Projects: 6 results

# of Collaborated Products: 67 results
2. 野口幸希 (10803661)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
3. HOSOYA Ken-ichi (70301033)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
4. TERASAKI Tetsuya (60155463)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. 牟田真理子 (40445193)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 千葉康司 (30458864)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. NAKASHIMA Emi (90115254)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
8. KOSE Noriko (60348612)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
9. SAI Yoshimichi (40262589)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 丸山哲夫 (10209702)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
11. 伊藤直樹 (20529177)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 石川源 (20287767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 佐村修 (90314757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 隹吉道

# of Collaborated Projects: 0 results

# of Collaborated Products: 8 results
15. 飯笹久

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 藤田有美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tomi Masatoshi 登美 斉俊

TOMI Masatoshi 登美 斉俊

Research Projects

Research Products

Co-Researchers

Ex vivo-in silicoハイブリッドによるヒト胎児薬物移行の新解析プラットフォーム構築Principal Investigator

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Prediction model for transplacental drug exposure to the human fetus based on species differences in placental transporters and plasma unbound concentrationsPrincipal Investigator

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Regulation of pharmacokinetics during pregnancy by placental exosomesPrincipal Investigator

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Review Section

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Significance of a balanced tryptophan diet for supporting fetal growthPrincipal Investigator

Principal Investigator

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Review Section

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Functional expression of sensing foctors against maternal osmotic stress in the placenta

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Medication for pregnant women based on 'barrier transition' behavior in feto-placental circulationPrincipal Investigator

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Food guide for pregnant women based on placental permeability of ingredientsPrincipal Investigator

Principal Investigator

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Fetal transfer mechanism of methyl donors across the placenta and its epigeneomesPrincipal Investigator

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Molecular basis of mechanisms underlying transplacental drugtransfer in corporation with placental endocrine functionPrincipal Investigator

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Establishment of human cell lines for blood-tissue barrier and application to elucidate mechanism of low-dose anti-cancer drugs

Principal Investigator

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Regulation mechanisms of the placental barrier for the maintenance of the fetal environment and their relevancies to the phenotypePrincipal Investigator

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血液網膜関門薬物排出輸送を制御する分子機構の解明Principal Investigator

Principal Investigator

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Research Institution

網膜ペリサイト分泌血管内皮細胞増殖抑制因子の同定

Principal Investigator

Project Period (FY)

Tomi Masatoshi 登美斉俊

TOMI Masatoshi 登美斉俊