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Kusakabe Yoshio  日下部 吉男

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… Alternative Names

日下部 吉男  クサカベ ヨシオ

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Researcher Number 30338537
Affiliation (Current) 2025: 帝京大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2023: 帝京大学, 薬学部, 講師
2015: 帝京大学, 薬学部, 講師
2013 – 2014: 昭和大学, 薬学部, 助教
2009: 昭和大, 薬学部, 助教
2007 – 2008: Showa University, 薬学部, 助教
2003 – 2005: 昭和大学, 薬学部, 助手
Review Section/Research Field
Principal Investigator
Drug development chemistry / Basic Section 53050:Dermatology-related
Except Principal Investigator
Basic Section 53050:Dermatology-related
Keywords
Principal Investigator
構造解析 / X線 / 構造生物学 / X線結晶構造解析 / 加水分解酵素 / 薬疹 / HLA / 重症薬疹 / インシリコ / 立体構造 … More / DIHS / 重症型薬疹 / アレルギー / 計算科学 / コドンの最適化 / ゲノム薬理 / VKORC1 / ワルファリン / 個別化医療 / アデノシン / 新規抗マラリア薬 / 結晶構造 / 結晶 / マラリア / 新規抗マラリア剤 / 結晶化 / 結晶構造解析 / 抗マラリア薬 / くぼみ / 挿入ループ / 抗マラリア剤 … More
Except Principal Investigator
3次元立体構造 / HLA / 中毒性表皮壊死症 / Stevens-Johnson症候群 / 重症型薬疹 Less
  • Research Projects

    (5 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (3 People)
  •  三次元立体構造解析・モデルマウスを用いたSJS/TEN治療薬の開発

    • Principal Investigator
      渡辺 秀晃
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Showa University
  •  Structural studies of HLA to develop of rational medicines for DIHS treatmentPrincipal Investigator

    • Principal Investigator
      Kusakabe Yoshio
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Teikyo University
  •  A structural study of VKORC1 for development of personalized medicinePrincipal Investigator

    • Principal Investigator
      Kusakabe Yoshio
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Teikyo University
      Showa University
  •  マラリア原虫由来加水分解酵素の立体構造に基づく抗マラリア薬の開発Principal Investigator

    • Principal Investigator
      日下部 吉男
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Showa University
  •  抗マラリア剤の開発を志向したマラリア原虫由来加水分解酵素の立体構造解析Principal Investigator

    • Principal Investigator
      日下部 吉男
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Drug development chemistry
    • Research Institution
      Showa University

All 2023 2016 2015 2009 2007 Other

All Journal Article Presentation Other

  • [Journal Article] Structural insights into the reaction mechanism of S-adenosyl-L-homocysteine hydrolase.2015

    • Author(s)
      Kusakabe, Y., Ishihara, M., Umeda, T., Kuroda, D., Nakanishi, M., Kitade, Y., Gouda, H., Nakamura, K., & Tanaka, N.
    • Journal Title

      Scientific Reports.

      Volume: 5 Pages: 16641-16641

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25860089
  • [Presentation] Drug eruption caused by anti-androgen drugs and reports of Stevens Johnson syndrome/toxic epidermal necrolysis in Japan.2023

    • Author(s)
      Kae Kobayashi, Mikiko Tohyama, Chisato Sunaga, Hiroomi Hosaka, Yoshio Kusakabe, Hideaki Watanabe
    • Organizer
      25th World congress of Dermatology, Singapore, 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08358
  • [Presentation] The effect of Baicalin on Annexin A1 in Stevens-Johnson syndrome/toxic epidermal necrolysis2023

    • Author(s)
      Yoshio Kusakabe
    • Organizer
      11th International Congress of Cutaneous Adverse Drug Reactions (iSCAR) 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K08358
  • [Presentation] 薬剤性過敏症症候群を引き起こす HLA の構造学的研究2016

    • Author(s)
      日下部 吉男, 渡辺 秀晃, 莚田 泰誠, 合田 浩明, 楯 直子
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-25860089
  • [Presentation] 新規感染症治療剤の開発を志向したマウス由来加水分解酵素の立体構造解析2009

    • Author(s)
      日下部吉男
    • Organizer
      日本薬学会第129年会
    • Place of Presentation
      京都国際会館
    • Year and Date
      2009-03-27
    • Data Source
      KAKENHI-PROJECT-19790096
  • [Presentation] Molecular basis for recognition of a selective nucleoside inhibitor by plasmodium falciparum S-adenosy-L-homocysteine hydrolase2007

    • Author(s)
      Yoshio, Kusakabe
    • Organizer
      The 8th Conference of the Asian Crystallographic Association
    • Place of Presentation
      台湾・台北
    • Year and Date
      2007-11-06
    • Data Source
      KAKENHI-PROJECT-19790096
  • []

  • 1.  渡辺 秀晃 (80327931)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  阿部 理一郎 (60344511)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  小林 香映 (90838640)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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