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TANAKA Motoyoshi  田中 基幹

ORCIDConnect your ORCID iD *help
Researcher Number 30347562
Other IDs
External Links
Affiliation (based on the past Project Information) *help 2010: 近畿大学, 医学部, 講師
2005 – 2008: 近畿大学, 医学部, 講師
2005: 奈良県立医科大学, 医学部, 学内講師
2004: 奈良医科大学, 医学部, 講師
2004: 奈良県立医科大学, 医学部, 助手
2004: Nana Medical Univ., Dept.of Urology, Instructor, 医学部・泌尿器科学, 助手
2003: 奈良県立医科大学, 泌尿器科, 助手
Review Section/Research Field
Principal Investigator
Urology
Except Principal Investigator
Urology / Experimental pathology
Keywords
Principal Investigator
前立腺癌 / 遺伝子治療 / PTEN癌抑制遺伝子 / ペプチド / 分子標的治療 / Peptide / PTEN Tumor Suppressor Gene / Molecular Therapy / Prostate Cancer / ペプチド療法 … More / 放射線療法 / 分子マーカー / gene therapy / PTEN tumor suppressor gene / Prostate cancer / PTEN / 動物モデル … More
Except Principal Investigator
ペプチドワクチン / 腎細胞癌 / CA9 / peptide vaceine / CA9 (Carbonic Anhydrase 9) / renal cell carcinoma / NADPH oxidase / hALKBH-8 / 免疫組織化学 / アポトーシス / 膀胱尿路上皮癌 / 活性酸素種 / ALKBH-8 / hABH-8 / 尿路上皮癌 / 腫瘍 / CA9抗原 / PDL / HIF-1α / EPOR / VEGFR / ペプチドワクチン療法 / 腎癌 Less
  • Research Projects

    (6 results)
  • Research Products

    (38 results)
  • Co-Researchers

    (13 People)
  •  The role of human ABH-8 in urothelial carcinoma

    • Principal Investigator
      SHIMADA Keiji
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Nara Medical University
  •  Development of tailor-madepeptide vaccines for renal eell carcinoma

    • Principal Investigator
      UEMURA Hirotsugu
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kinki University
  •  Novel molecular therapeutic strategies in prostate cancerPrincipal Investigator

    • Principal Investigator
      TANAKA Motoyoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kinki University
  •  Molecular Therapy Targeting PTEN-Akt Signaling Pathway in Prostate Cancer.Principal Investigator

    • Principal Investigator
      TANAKA Motoyoshi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Kinki University
      Nara Medical University
  •  Development new generation peptides derived from CA9 as tailar-made vaccines for renal cell carcinoma

    • Principal Investigator
      UEMURA Hirotsugu
    • Project Period (FY)
      2004 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Urology
    • Research Institution
      Kinki University
  •  Application for PTEN Gene Therapy in Prostate CancerPrincipal Investigator

    • Principal Investigator
      TANAKA Motoyoshi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Nara Medical University School of Medicine

All 2010 2009 2008 2007 2006 2005

All Journal Article Presentation

  • [Journal Article] Role of syndecan-1 (CD138) in cell survival of human urothelial carcinoma.2010

    • Author(s)
      Shimada K, Nakamura M, De Velasco MA, Tanaka M, Ouji Y, Miyake M, Fujimoto K, Hirao K, Konishi N.
    • Journal Title

      Cancer Sci. Vol.101, No.1

      Pages: 155-160

    • NAID

      10027199949

    • Data Source
      KAKENHI-PROJECT-21790392
  • [Journal Article] PTEN-Knockout Prostate Cancer as a Model for Experimental Immunotherapy2009

    • Author(s)
      Haga, K., Tomioka, A., Liao, C. P., Kimura, T., Matsumoto, H., Ohno, I., Hermann; K., Logg, C.R., Tanaka, Hirao, Y., Hong Wu, H., Kruse, C. A., Roy-Burman, P., Kasahara, N.
    • Journal Title

      Journal of Urology 181

      Pages: 354-362

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Journal Article] A novel human AlkB homologue, ALKBH8, contributes to human bladder cancer progression.2009

    • Author(s)
      Shimada K, Nakamura M, Anai S, De Velasco M, Tanaka M, Tsujikawa K, Ouji Y, Konishi N.
    • Journal Title

      Cancer Res. Vol.69, No.7

      Pages: 3157-3164

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790392
  • [Journal Article] GFP image analysis in the mouse orthotopic bladder cancer model2008

    • Author(s)
      De Velasco M., Tanaka M., Uemura H, 他3名
    • Journal Title

      Oncol Rep 20

      Pages: 537-542

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390419
  • [Journal Article] Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation2008

    • Author(s)
      Tomioka, A., Tanaka, M., DeVelasco, M. Anai, S., Takada, S., Kushibiki, T., Tabata, Y., Rosser, C. J., Uemura, H., Hirao, H.
    • Journal Title

      Molecular Cancer Therapeutics 7

      Pages: 1864-1870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Journal Article] GFP image analysis in the mouse orthotopic bladder cancer model2008

    • Author(s)
      DeVelasco, M., Tanaka, M., Anai, S., Tomioka, A., Nishio, K., Uemura, H.
    • Journal Title

      Oncology Report 20

      Pages: 537-542

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Journal Article] Delivery of PTEN via a novel gene microcapsule sensitizes prostate cancer cells to irradiation2008

    • Author(s)
      Tomioka A., Tanaka M., De Velasco M. Uemura H, 他7名
    • Journal Title

      Mol Cancer Ther 7

      Pages: 1864-1870

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390419
  • [Journal Article] Phase I/II study of individualized peptide vaccines for HLA-A2/24 positive patients with hormone-refractory prostate cancer2008

    • Author(s)
      Uemura H., Minami T., Tanaka M, 他4名
    • Journal Title

      J. Clin. Oncol. 26

    • Data Source
      KAKENHI-PROJECT-19390419
  • [Journal Article] c-Jun NH2 terminal kinase activation and decreased expression of mitogen-activated protein kinase phosphatase-1 play important roles in invasion and angiogenesis of urothelial carcinomas2007

    • Author(s)
      Shimada, K., Nakamura, M., Ishida, E., Higuchi, T., Tanaka, M., Ota, I., Konishi, N.
    • Journal Title

      American Journal of Pathology 171

      Pages: 1003-1012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Journal Article] Increased expression of cyclooxygenase-2 correlates with resistance to radiation in human prostate adenocarcinoma cells2007

    • Author(s)
      Anai, S., Tanaka, M., Shiverick, K. T., Kim, W., Takada, S., Boehlein, S., Goodison, S., Mizokami, A., Rosser, C. J.
    • Journal Title

      Journal of Urology 177

      Pages: 1913-1917

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Journal Article] Combination of PTEN Gene Therapy and Radiation Inhibits the Growth of Human Prostate Cancer Xenografts.2006

    • Author(s)
      Anai S, Goodison S, Shiverick K, Iczkowski K, Tanaka M, Rosser CJ
    • Journal Title

      Human Gene Therapy 17

      Pages: 675-984

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] A phase I trail of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma2006

    • Author(s)
      Uemura H., Fujimoto K., Tanaka M., et al.
    • Journal Title

      Clin Cancer Res 12・6

      Pages: 1768-1775

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-16390468
  • [Journal Article] A phase I trial of vaccination of CA9-derived peptides for HLA-A24-positive patients With cytokine-refractory metastatic renal cell carcinoma.2006

    • Author(s)
      Uemura H, Fujimoto K, Tanaka M, Yoshikawa M, Hirao Y, Uejima S, Yoshikawa K, Itoh K
    • Journal Title

      Clinical Cancer Research 12

      Pages: 1768-1775

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] A phase l trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma.2006

    • Author(s)
      Uemura H, Fujimoto K, Tanaka M, Yoshikawa M, Hirao Y, Uejima S, Yoshikawa K, Itoh K
    • Journal Title

      Clinical Cancer Research 12

      Pages: 1768-1775

    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] Combination of PTEN Gene Therapy and Radiation Inhibits the Growth of Human Prostate Cancer Xenografts.2006

    • Author(s)
      Anai S, Goodison S, Shiverick K, Iczkowski K, Tanaka M, Rosser CJ.
    • Journal Title

      Human Gene Therapy 17

      Pages: 675-684

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] A phase I trail of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renalcell carcinoma2006

    • Author(s)
      Uemura H, Fujimoto K, Tanaka M., et al.
    • Journal Title

      Clin Cancer Res 12・6

      Pages: 1768-1775

    • Data Source
      KAKENHI-PROJECT-16390468
  • [Journal Article] PTEN gene therapy induces growth inhibition and increases efficacy of chemotherapy in prostate-cancer.2005

    • Author(s)
      Tanaka, M., Rosser, C.J., Grossman, H.B.
    • Journal Title

      Cancer Detection and Prevention 29

      Pages: 170-174

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] A phase I trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine-refractory metastatic renal cell carcinoma.2005

    • Author(s)
      Uemura H, Fujimoto K, Tanaka M, Yoshikawa M, Hirao Y, Uejima S, Yoshikawa K, Itoh K.
    • Journal Title

      Clinical Cancer Research 12

      Pages: 1768-1775

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] PTEN gene therapy induces growth inhibition and increases efficacy of chemotherapy in prostate cancer.2005

    • Author(s)
      Tanaka, M., Rosser, C.J., Grossman, H.B.
    • Journal Title

      Cancer Detection and Prevention 29

      Pages: 170-174

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Journal Article] Intravesical administration of small interfering RNA targeting PLK-1 successfully prevents the growth of bladder cancer.2005

    • Author(s)
      Nogawa, M., Yuasa, T., Kimura, S., Tanaka, M., Kuroda, J., Sato, K., Yokota, A., Segawa, H., Toda, Y., Kageyama, S., Yoshiki, T., Okada, Y., Maekawa, T.
    • Journal Title

      Journal of Clinical Investigation 115

      Pages: 978-985

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-17591697
  • [Presentation] The role of syndecan-1 (CD138) in progression of human urinary bladder cancer2009

    • Author(s)
      Shimada, K., Nakamura, M., Marco A. De Velasco, Tanaka, M., Konishi, N.
    • Organizer
      第68回日本癌学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2009-10-02
    • Data Source
      KAKENHI-PROJECT-21790392
  • [Presentation] 年齢別PSAカットオフ値および体積・年齢別生検本数ノモグラムを用いた前立腺生検の試み2009

    • Author(s)
      田中宣道, 島田啓司, 他
    • Organizer
      第97回日本泌尿器科学会総会
    • Place of Presentation
      岡山
    • Data Source
      KAKENHI-PROJECT-21790392
  • [Presentation] A novel PTEN functional peptide therapy for prostate cancer2008

    • Author(s)
      M. Tanaka
    • Organizer
      The 14^<th> Annual Meeting 2008 Japan Society of Gene Therapy
    • Place of Presentation
      札幌市
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] p16 peptide therapy radiosensitizes in prostate cancer orthotopic model2008

    • Author(s)
      Tanaka, M
    • Organizer
      第67回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Prostate cancer mouse model derived by PTEN conditional gene targeting ; Towards pre-clinical appliocation2008

    • Author(s)
      Tanaka, M
    • Organizer
      The 24^<th> Annual Meeting of Urological Research Society
    • Place of Presentation
      Amsterdam (Netherlands)
    • Year and Date
      2008-09-19
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] A novel PTEN functional peptide therapy for prostate cancer2008

    • Author(s)
      Tanaka, M
    • Organizer
      第14回日本遺伝子治療学会
    • Place of Presentation
      札幌
    • Year and Date
      2008-06-12
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] PTEN機能ペプチドによる前立腺癌治療への応用2008

    • Author(s)
      田中基幹
    • Organizer
      第96回日本泌尿器科学会総会
    • Place of Presentation
      横浜
    • Year and Date
      2008-04-25
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] 4074 PTEN functional peptide therapy in prostate cancer2008

    • Author(s)
      M. Tanaka
    • Organizer
      AACR Annual Meeting 2008
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2008-04-15
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Pten functional peptide therapy in prostate cancer2008

    • Author(s)
      Tanaka, M
    • Organizer
      第67回日本癌学会総会
    • Place of Presentation
      名古屋
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] PTEN機能性ペプチドによる前立腺癌治療の試み2008

    • Author(s)
      田中基幹
    • Organizer
      第67回日本癌学会学術総会
    • Place of Presentation
      名古屋市
    • Year and Date
      2008-10-29
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Metabolic syndrome accelerates mouse prostate cancer development2008

    • Author(s)
      田中基幹
    • Organizer
      第17回泌尿器分子・細胞研究会
    • Place of Presentation
      東京
    • Year and Date
      2008-02-16
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Pten gene targetingの手法を用いたマウス前立腺癌モデルとその臨床に向けた応用2008

    • Author(s)
      田中基幹
    • Organizer
      前立腺シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2008-12-13
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Pten functional peptide therapy in prostate cancer2008

    • Author(s)
      Tanaka, M
    • Organizer
      The 99^<th> Annual Meeting, American Association for Cancer Research
    • Place of Presentation
      San Diego (USA)
    • Year and Date
      2008-04-15
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] The role of PTEN in carcinogenesis of mouse prostate.2007

    • Author(s)
      Tanaka, M
    • Organizer
      The 23^<rd> Annual Meeting of Urological Research Society, ct.
    • Place of Presentation
      Napa (USA)
    • Year and Date
      2007-10-27
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] The Role of PTEN Tumor Suppressor Gene in Prostate Cancer Derived by Prostate Specific Deletion of PTEN2007

    • Author(s)
      Tanaka, M
    • Organizer
      The 10^<th>Annual Meeting of the American Society of Gene Therapy
    • Place of Presentation
      Seattle USA
    • Year and Date
      2007-03-30
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] 表在性膀胱癌マウスモデルを用いたリポソーム化ドキソルビシンの治療効果2007

    • Author(s)
      田中基幹
    • Organizer
      第16回日本腎泌尿器予防医学研究会
    • Place of Presentation
      大阪
    • Year and Date
      2007-07-13
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Intravesical instillation of liposomal doxorubicin nanoparticles in mouse superficial bladder cancer2007

    • Author(s)
      Tanaka, M
    • Organizer
      The102^<nd> Annual Meeting, American Urological Association, Inc.
    • Place of Presentation
      Anaheim (USA)
    • Year and Date
      2007-05-21
    • Data Source
      KAKENHI-PROJECT-19591876
  • [Presentation] Intravesical treatment of liposomal doxorubicin nanoparticles in mouse orthotopic bladder cancer model2007

    • Author(s)
      Tanaka, M
    • Organizer
      The 98^<th> Annual Meeting, American Association for Cancer Research
    • Place of Presentation
      Los Angeles USA
    • Year and Date
      2007-04-15
    • Data Source
      KAKENHI-PROJECT-19591876
  • 1.  UEMURA Hirotsugu (90213397)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 10 results
  • 2.  YOSHIKAWA Kazuhiro (60109759)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 3.  HIRAO Yoshihiko (00133207)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  SHIMADA Keiji (90336850)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 5.  DEVELASCO Marco (20449838)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  NOZAWA Masahiro (00441080)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  UEJIMA Shigeya (60213336)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  KONISHI Noboru (20145832)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 9.  MINAMI Takafumi (70340809)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  TSUJIKAWA Kazutake (10207376)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  OUJI Yukiteru (50343421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  FUJIMOTO Kiyohide (50264867)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 13.  TANAKA Masahiro (00382292)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results

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