NAGAO Tetsuji 長尾哲二

Researcher Number	30351563
Other IDs
Affiliation (based on the past Project Information) *help	2017 – 2020: 近畿大学, 理工学部, 教授 2010 – 2014: 近畿大学, 理工学部, 教授
Review Section/Research Field	Principal Investigator Risk sciences of radiation and chemicals / Risk sciences of radiation/Chemicals Except Principal Investigator General anatomy (including histology/embryology) / Risk sciences of radiation/Chemicals
Keywords	Principal Investigator 有害化学物質 / 細胞・組織 / 神経科学 / 海馬歯状回 / 液性因子 / 免疫組織染色 / ニューロン新生 / ミクログリア活性異常 / 大脳皮質 / 神経発生毒性 … More / ミクログリア活性 / 炎症因子 / ミクログリア / 化学物質曝露 / 神経発生発達毒性 / DNAメチル化酵素 / エピジェネティックス / 精巣毒性 / DNAメチル化 / Dnmt / ＤＮＡメチル化 / Ｄｎｍｔ / エピジェネティクス / 継世代影響 / 催奇形性 / 合成エストロゲン … More Except Principal Investigator 発生・分化 / 細胞・組織 / 脳・神経 / 神経科学 / 解剖学 / 先天異常 / 神経炎症 / 視床下部 / エタノール / 神経発達毒性 / ビスフェノールA / フタル酸エステル / 発達障害 / 感染症 / ストレス / バルプロ酸 / 母胎内環境 / 神経新生 / 海馬歯状回 / 大脳皮質 / 脳内炎症 / ミクログリア / 染色体異常 / 変異原性 / 生物学的効果比 / 誘発率 / 小核 / 奇形 / 突然変異 / 器官形成期 / マウス胎児 / 核分裂中性子 Less

Neurodevelopmental toxicities of chemicals are related to an increased microglial activation and neuroinflammation in the neocortexPrincipal Investigator
- Principal Investigator
  
  NAGAO Tetsuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kindai University
Elucidation of the mechanism of microglial transition in brain construction and its significance
- Principal Investigator
  
  Komada Munekazu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Kindai University
  Aichi Medical University
Studies on mutagenicity and related toxicity of fission neutrons in fetal mice
- Principal Investigator
  
  FUJIKAWA Kazuo
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kinki University
Transgenerational teratogenesis by prenatal exposure to environmental chemicals in micePrincipal Investigator
- Principal Investigator
  
  NAGAO Tetsuji
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation/Chemicals
- Research Institution
  Kinki University

All 2020 2019 2018 2017 2012 2011 2010

All Journal Article Presentation

[Journal Article] Postnatal di-2-ethylhexyl phthalate exposure affects hippocampal dentate gyrus morphogenesis2020
- Author(s)
  Komada M, Nagao T, Kagawa N.
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 40 Issue: 12 Pages: 1673-1682
- DOI
  10.1002/jat.4027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08500
[Journal Article] Maternal administration of bisphenol A alters the microglial profile in the neocortex of mouse weanlings2020
- Author(s)
  Kagawa Nao、Nagao Tetsuji
- Journal Title
  
  Congenital Anomalies
  
  Volume: - Issue: 5 Pages: 142-146
- DOI
  10.1111/cga.12370
- NAID
  50014579010
- Data Source
  KAKENHI-PROJECT-17K08500
[Journal Article] Prenatal and postnatal bisphenol A exposure inhibits postnatal neurogenesis in the hippocampal dentate gyrus2020
- Author(s)
  Komada M, Nagao T, Kagawa N.
- Journal Title
  
  Journal of Toxicological Sciences
  
  Volume: 45 Issue: 10 Pages: 639-650
- DOI
  10.2131/jts.45.639
- NAID
  130007921909
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08500
[Journal Article] The neonicotinoids acetamiprid and imidacloprid impair neurogenesis and alter the microglial profile in the hippocampal dentate gyrus of mouse neonates2019
- Author(s)
  Nakayama Akira、Yoshida Manami、Kagawa Nao、Nagao Tetsuji
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 39 Issue: 6 Pages: 877-887
- DOI
  10.1002/jat.3776
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08500, KAKENHI-PROJECT-17K00572
[Journal Article] Exposure to bisphenol A affects GABAergic neuron differentiation in neurosphere cultures.2018
- Author(s)
  Fukushima Nobuyuki、Nagao Tetsuji
- Journal Title
  
  NeuroReport
  
  Volume: 印刷中 Issue: 9 Pages: 712-717
- DOI
  10.1097/wnr.0000000000001021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00572
[Journal Article] Neurodevelopmental toxicity in the mouse neocortex following prenatal exposure to acetamiprid2018
- Author(s)
  Kagawa Nao、Nagao Tetsuji
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 38 Issue: 12 Pages: 1521-1528
- DOI
  10.1002/jat.3692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00572
[Journal Article] Endocrine disrupting chemicals, 4-nonylphenol, bisphenol A and butyl benzyl phthalate, impair metabolism of estradiol in male and female rats as assessed by levels of 15α-hydroxyestrogens and catechol estrogens in urine2017
- Author(s)
  Nakagomi Madoka、Suzuki Emako、Saito Yoshiaki、Nagao Tetsuji
- Journal Title
  
  Journal of Applied Toxicology
  
  Volume: 38 Issue: 5 Pages: 688-695
- DOI
  10.1002/jat.3574
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00572
[Journal Article] Mechanisms underlying neuro-inflammation and neurodevelopmental toxicity in the mouse neocortex following prenatal exposure to ethanol2017
- Author(s)
  Komada Munekazu、Hara Nao、Kawachi Satoko、Kawachi Kota、Kagawa Nao、Nagao Tetsuji、Ikeda Yayoi
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 4934-4934
- DOI
  10.1038/s41598-017-04289-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08476, KAKENHI-PROJECT-17K00572, KAKENHI-PROJECT-17K08500
[Journal Article] Newly developed mouse newborn behavioral testing method for evaluating the risk of neurotoxicity of environmental toxicants2012
- Author(s)
  Nagao T, Komada M, Kagawa N
- Journal Title
  
  J Appl Toxicol
  
  Volume: - Issue: 12 Pages: 1514-1519
- DOI
  10.1002/jat.2802
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510078, KAKENHI-PROJECT-24700353
[Journal Article] Developmental effects of oral exposure to diethylstilbestrol on mouse placenta2012
- Author(s)
  Nagao T, Kagawa N, Saito Y, Komada M.
- Journal Title
  
  J Appl Toxicol
  
  Volume: - Issue: 11 Pages: 1213-1221
- DOI
  10.1002/jat.2766
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510078
[Journal Article] Maternal bisphenol A oral dosing relates to the acceleration of neurogenesis in the developing neocortex of mouse fetuses2012
- Author(s)
  Komada, M., et al
- Journal Title
  
  Toxicology
  
  Volume: 295(1-3) Issue: 1-3 Pages: 31-8
- DOI
  10.1016/j.tox.2012.02.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390052, KAKENHI-PROJECT-22510078, KAKENHI-PROJECT-22790186, KAKENHI-PROJECT-23659092
[Journal Article] Transgenerational teratogenesis by prenatal exposure to endocrine disrupting chemicals2011
- Author(s)
  Nagao T, Takada N, Onoda N.
- Journal Title
  
  Genes and Environ
  
  Volume: 33 Pages: 50-60
- NAID
  10028110846
- URL
  http://dx.doi.org/10.3123/jemsge.33.50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510078
[Journal Article] Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos2010
- Author(s)
  Komada M, Fujiyama F, Yamada S, Shiota K, Nagao T.
- Journal Title
  
  Birth Defects Res B Dev Reprod Toxicol
  
  Volume: 89(3) Issue: 3 Pages: 213-222
- DOI
  10.1002/bdrb.20245
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22510078
[Presentation] Prenatal exposure to valproic acid induces dysplasia of the neocortex and neuro-inflammation in mice.2019
- Author(s)
  Komada M, Kamiyama H, Kagawa N, Nagao T.
- Organizer
  The 59th Annual Meeting of Japanese Teratology Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00572
[Presentation] Prenatal exposure to valproic acid induces dysplasia of the neocortex and neuro-inflammation in mice.2019
- Author(s)
  Munekazu Komada, Haruka Kamiyama, Nao Kagawa, Tetsuji Nagao
- Organizer
  第59回日本先天異常学術集会　13th World Congress of The International Cleft Lip and Palate Foundation CLEFT2019 （合同開催）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08500
[Presentation] 子宮内メチル水銀曝露した児マウスにおける第三脳室上衣細胞繊毛運動低下について2018
- Author(s)
  萩野大、萩原央記、南武志、長尾哲二、巽純子
- Organizer
  日本先天異常学会第58回学術集会
- Data Source
  KAKENHI-PROJECT-17K00572
[Presentation] Developmental exposure to methyl mercury decreased ciliary movement of ependymal cells in the third ventricle of mice.2018
- Author(s)
  Hagino H, Hagiwara T, Tatsumi J, Nagao T, Minami T.
- Organizer
  The 8th International Congress of ASIAN Society of Toxicology (ASIATOX 2018)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00572
[Presentation] Developmental exposure to methyl mercury decreased ciliary movement of ependymal cells in the third ventricle of mice.2018
- Author(s)
  Hagino H, Hagiwara T, Tatsumi J, Nagao T, Minami T.
- Organizer
  The 8th International Congress of ASIAN Society of Toxicology (ASIATOX 2018).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K00572
[Presentation] 胎児期低用量ビスフェノールA曝露は炎症を伴うミクログリアの異常を誘発する2017
- Author(s)
  駒田致和、高橋美文、長尾哲二、池田やよい
- Organizer
  日本先天異常学会第57回学術集会
- Data Source
  KAKENHI-PROJECT-17K00572
[Presentation] 胎児期低用量ビスフェノールA曝露は炎症を伴うミクログリアの異常を誘発する2017
- Author(s)
  駒田致和、高橋美文、長尾哲二、池田やよい
- Organizer
  第57回日本先天異常学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08500
[Presentation] 胎児期4-ヒドロキシタモキシフェン曝露はマウス大脳皮質形成を障害する2012
- Author(s)
  溝端彩、森佳奈美、駒田致和、長尾哲二
- Organizer
  環境ホルモン学会第15回研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510078
[Presentation] 合成エストロゲン剤のマウス胎盤傷害性と胚致死作用2012
- Author(s)
  長尾哲二、加川尚、斎藤義明、駒田致和
- Organizer
  日本先天異常学会第52回学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510078
[Presentation] 低用量ビスフェノールAのマウス子宮内曝露は新生児の出生直後の活動量に影響を及ぼす2012
- Author(s)
  長尾哲二、井藤早紀、正見寛子、駒田致和
- Organizer
  環境ホルモン学会第15回研究発表会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510078
[Presentation] 胎児期低用量ビスフェノールA曝露は大脳皮質形成において神経新生を促進する2012
- Author(s)
  駒田致和、浅井泰子、守井見奈、松木美知枝、佐藤真、長尾哲二
- Organizer
  日本先天異常学会第52回学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22510078

1. KAGAWA Nao (80351568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
2. Komada Munekazu (90523994)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. FUJIKAWA Kazuo (90247958)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 福嶋伸之 (10254161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 池田やよい

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 池田正明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAGAO Tetsuji 長尾 哲二

Research Projects

Research Products

Co-Researchers

Neurodevelopmental toxicities of chemicals are related to an increased microglial activation and neuroinflammation in the neocortexPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of microglial transition in brain construction and its significance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on mutagenicity and related toxicity of fission neutrons in fetal mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Transgenerational teratogenesis by prenatal exposure to environmental chemicals in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Postnatal di-2-ethylhexyl phthalate exposure affects hippocampal dentate gyrus morphogenesis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Maternal administration of bisphenol A alters the microglial profile in the neocortex of mouse weanlings2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Prenatal and postnatal bisphenol A exposure inhibits postnatal neurogenesis in the hippocampal dentate gyrus2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The neonicotinoids acetamiprid and imidacloprid impair neurogenesis and alter the microglial profile in the hippocampal dentate gyrus of mouse neonates2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Exposure to bisphenol A affects GABAergic neuron differentiation in neurosphere cultures.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neurodevelopmental toxicity in the mouse neocortex following prenatal exposure to acetamiprid2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endocrine disrupting chemicals, 4-nonylphenol, bisphenol A and butyl benzyl phthalate, impair metabolism of estradiol in male and female rats as assessed by levels of 15α-hydroxyestrogens and catechol estrogens in urine2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanisms underlying neuro-inflammation and neurodevelopmental toxicity in the mouse neocortex following prenatal exposure to ethanol2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Newly developed mouse newborn behavioral testing method for evaluating the risk of neurotoxicity of environmental toxicants2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Developmental effects of oral exposure to diethylstilbestrol on mouse placenta2012

Author(s)

Journal Title

DOI

Data Source

NAGAO Tetsuji 長尾哲二