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TAKETANI Takeshi  竹谷 健

ORCIDConnect your ORCID iD *help
Researcher Number 30359880
Other IDs
Affiliation (Current) 2025: 島根大学, 学術研究院医学・看護学系, 教授
Affiliation (based on the past Project Information) *help 2018 – 2024: 島根大学, 学術研究院医学・看護学系, 教授
2016 – 2017: 島根大学, 医学部, 教授
2007 – 2016: Shimane University, 医学部, 講師
2003 – 2006: 島根大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Pediatrics / Basic Section 52050:Embryonic medicine and pediatrics-related / Basic Section 52050:Embryonic medicine and pediatrics-related
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Embryonic/Neonatal medicine
Keywords
Principal Investigator
FLT3 / 白血病 / 低ホスファターゼ症 / 間葉系幹細胞 / WT1 / RAS / HOX / NUP98 / FLT3遺伝子 / 脂肪酸代謝異常症 … More / 低ホスファターぜ症 / ミトコドリア / 先天代謝異常症 / ミトコンドリア病 / メタボローム / stemness / メタボローム解析 / タウリン / ウイルス感染 / 小児白血病 / APOBEC3B / FLT3-ITD / HOXA9 / NRAS / NUP98-HOXA9 / KIT / MDS / AML / 急性骨髄性白血病 / Leukemia / 11q23 / MLL / MLL遺伝子 / 乳児白血病 / Rapamycin / HOX遺伝子 / NUP98遺伝子 … More
Except Principal Investigator
再生医療 / 薬剤耐性機構 / 急性骨髄性白血病 / 疾患多様性 / タンデムマス法 / 有機酸血症 / アミノ酸血症 / ハイリスクスクリーニング / 遺伝疫学 / 疾患発見頻度 / 疾患頻度 / アジア諸国 / 対象疾患 / 国際比較 / 国際協力 / アジア / 疫学調査 / 障害予防 / 脂肪酸代謝異常症 / 有機酸代謝異常症 / タンデムマス / 新生児マススクリーニング / 間葉系幹細胞 / 低フォスファターゼ症 / 慢性呼吸器疾患 / 脳性麻痺 / 肝炎 / 血友病 / 免疫学 / 再生医学 / トランスレーショナルリサーチ / 移植・再生医療 / 新生児脳症 / 新生児 / 免疫療法 / 血友病B / 新生児慢性肺疾患 / 新生児脳性麻痺 / 間葉系細胞 / 臍帯 Less
  • Research Projects

    (12 results)
  • Research Products

    (63 results)
  • Co-Researchers

    (22 People)
  •  Molecular Mechanism Responsible for the FLT3 Inhibitor-Dependent-Proliferation of Resistant FLT3/ITD+ cells

    • Principal Investigator
      福田 誠司
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Sugiyama Jogakuen University
  •  ミトコンドリア病モデル動物に対する高純度間葉系幹細胞の治療効果の検証Principal Investigator

    • Principal Investigator
      竹谷 健
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shimane University
  •  Highly Purified Mesenchymal Stem Cell Therapy for Neuropathy of Congenital Metabolic Disorders Involved on MitochondriaPrincipal Investigator

    • Principal Investigator
      竹谷 健
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shimane University
  •  Investigation of the diversity of metabolic pathways affecting stemness in mesenchymal stem cellsPrincipal Investigator

    • Principal Investigator
      Taketani Takeshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shimane University
  •  Study of diversity in organic and fatty acid disorders in Asia

    • Principal Investigator
      Yamaguchi Seiji
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Shimane University
  •  Pathogenesis of APOBEC3B in childhood leukemiaPrincipal Investigator

    • Principal Investigator
      TAKETANI TAKESHI
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University
  •  Development of therapeutic technology for hypophosphatasia using genetically corrected mesenchymal stem cells

    • Principal Investigator
      Oda Yasuaki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      Shimane University
  •  New tissue-repair and immuno-regulatory therapy with umbilical cord-derived mesenchymal stromal cells

    • Principal Investigator
      Nagamura-Inoue Tokiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Embryonic/Neonatal medicine
    • Research Institution
      The University of Tokyo
  •  Leukemogenesis between NUP98-HOX fusion genes and concomitant mutationsPrincipal Investigator

    • Principal Investigator
      TAKETANI Takeshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University
  •  Investigation of pathogenesis of leukemia with NUP98-HOX fusion genePrincipal Investigator

    • Principal Investigator
      TAKETANI Takeshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University
  •  Efficacy of Rapamycin in leukemia with chromosomal 11q23 translocationPrincipal Investigator

    • Principal Investigator
      TAKETANI Takeshi
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University
  •  11p15転座型白血病のNUP98遺伝子の相手遺伝子の単離とその機能解析Principal Investigator

    • Principal Investigator
      竹谷 健
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Shimane University
      Shimane Medical University

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 2004 Other

All Journal Article Presentation Patent

  • [Journal Article] MELAS-Derived Neurons Functionally Improve by Mitochondrial Transfer from Highly Purified Mesenchymal Stem Cells (REC)2023

    • Author(s)
      Liu Lu、Yang Jiahao、Otani Yoshinori、Shiga Takahiro、Yamaguchi Akihiro、Oda Yasuaki、Hattori Miho、Goto Tsukimi、Ishibashi Shuichi、Kawashima-Sonoyama Yuki、Ishihara Takaya、Matsuzaki Yumi、Akamatsu Wado、Fujitani Masashi、Taketani Takeshi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 24 Issue: 24 Pages: 17186-17186

    • DOI

      10.3390/ijms242417186

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K07267, KAKENHI-PROJECT-23K07290, KAKENHI-PROJECT-21K06066, KAKENHI-PROJECT-22KJ2745, KAKENHI-PROJECT-21H02814, KAKENHI-PROJECT-23K27567
  • [Journal Article] A Simple Flow Injection Analysis-Tandem Mass Spectrometry Method to Reduce False Positives of C5-Acylcarnitines Due to Pivaloylcarnitine Using Reference Ions2022

    • Author(s)
      Takanari Hattori, Yoshitomo Notsu, Misa Tanaka, Miki Matsui, Tetsuo Iida, Jun Watanabe, Yoshimitsu Osawa, Seiji Yamaguchi, Shozo Yano, Takeshi Taketani, Hironori Kobayashi
    • Journal Title

      Children

      Volume: 9 Issue: 5 Pages: 694-694

    • DOI

      10.3390/children9050694

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08347
  • [Journal Article] Clinical and molecular investigation of 37 Japanese patients with multiple acyl-CoA dehydrogenase deficiency: p.Y507D in ETFDH, a common Japanese variant, causes a mortal phenotype2022

    • Author(s)
      Yamada Kenji、Osawa Yoshimitsu、Kobayashi Hironori、Bo Ryosuke、Mushimoto Yuichi、Hasegawa Yuki、Yamaguchi Seiji、Taketani Takeshi
    • Journal Title

      Molecular Genetics and Metabolism Reports

      Volume: 33 Pages: 100940-100940

    • DOI

      10.1016/j.ymgmr.2022.100940

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08300, KAKENHI-PROJECT-19K08347
  • [Journal Article] The frequencies of very long-chain acyl-CoA dehydrogenase deficiency genetic variants in Japan have changed since the implementation of expanded newborn screening2022

    • Author(s)
      Osawa Yoshimitsu、Kobayashi Hironori、Tajima Go、Hara Keiichi、Yamada Kenji、Fukuda Seiji、Hasegawa Yuki、Aisaki Junko、Yuasa Miori、Hata Ikue、Okada Satoshi、Shigematsu Yosuke、Sasai Hideo、Fukao Toshiyuki、Takizawa Takumi、Yamaguchi Seiji、Taketani Takeshi
    • Journal Title

      Molecular Genetics and Metabolism

      Volume: 136 Issue: 1 Pages: 74-79

    • DOI

      10.1016/j.ymgme.2022.03.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07753, KAKENHI-PROJECT-19K08300, KAKENHI-PROJECT-22K07889, KAKENHI-PROJECT-19K08347
  • [Journal Article] Long-Term Neurological Outcomes of Adult Patients with Phenylketonuria before and after Newborn Screening in Japan2021

    • Author(s)
      Yamada Kenji、Yamaguchi Seiji、Yokoyama Kazunori、Aoki Kikumaro、Taketani Takeshi
    • Journal Title

      International Journal of Neonatal Screening

      Volume: 7 Issue: 2 Pages: 21-21

    • DOI

      10.3390/ijns7020021

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08300, KAKENHI-PROJECT-19K08347
  • [Journal Article] Diagnosis of mucopolysaccharidoses and mucolipidosis as-saying multiplex enzymes and glycosaminoglycans2021

    • Author(s)
      Arunkumar N, Vu DC, Khan S, Kobayashi H, Ngoc Can TB, Oguni T, Watanabe J, Tanaka M, Yamaguchi S, Taketani T, Ago Y, Ohnishi H, Saikia S, Álvarez JV, Tomatsu S.
    • Journal Title

      Diagnostics (Basel)

      Volume: 11 Issue: 8 Pages: 1347-62

    • DOI

      10.3390/diagnostics11081347

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08347
  • [Journal Article] Need for strict clinical management of patients with carnitine palmitoyltransferase II deficiency: Experience with two cases detected by expanded newborn screening2020

    • Author(s)
      Bo Ryosuke、Musha Ikuma、Yamada Kenji、Kobayashi Hironori、Hasegawa Yuki、Awano Hiroyuki、Arao Masato、Kikuchi Toru、Taketani Takeshi、Ohtake Akira、Yamaguchi Seiji、Iijima Kazumoto
    • Journal Title

      Molecular Genetics and Metabolism Reports

      Volume: 24 Pages: 100611-100611

    • DOI

      10.1016/j.ymgmr.2020.100611

    • NAID

      120006882474

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09969, KAKENHI-PROJECT-19K08300, KAKENHI-PROJECT-19K08347, KAKENHI-PROJECT-19K17298
  • [Journal Article] Long-Term Outcomes of Adult Patients with Homocystinuria before and after Newborn Screening2020

    • Author(s)
      Yamada Kenji、Yokoyama Kazunori、Aoki Kikumaro、Taketani Takeshi、Yamaguchi Seiji
    • Journal Title

      International Journal of Neonatal Screening

      Volume: 6 Issue: 3 Pages: 60-60

    • DOI

      10.3390/ijns6030060

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08300, KAKENHI-PROJECT-19K08347
  • [Journal Article] Clinical course in a patient with myopathic VLCAD deficiency during pregnancy with an affected baby2019

    • Author(s)
      Yamada Kenji、Matsubara Keiichi、Matsubara Yuko、Watanabe Asami、Kawakami Sanae、Ochi Fumihiro、Kuwabara Kozue、Mushimoto Yuichi、Kobayashi Hironori、Hasegawa Yuki、Fukuda Seiji、Yamaguchi Seiji、Taketani Takeshi
    • Journal Title

      JIMD Reports

      Volume: 49 Issue: 1 Pages: 17-20

    • DOI

      10.1002/jmd2.12061

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08300, KAKENHI-PROJECT-19K08347, KAKENHI-PROJECT-16K09969, KAKENHI-PROJECT-16K21179
  • [Journal Article] Single nucleotide polymorphisms of the DGKB and VCAM1 genes are associated with granulocyte colony stimulating factor-mediated peripheral blood stem cell mobilization.2017

    • Author(s)
      Mishima S, Matsuda C, Ishihara T, Nagase M, Taketani T, Nagai A.
    • Journal Title

      Transfus Apher Sci

      Volume: 56 Issue: 2 Pages: 154-159

    • DOI

      10.1016/j.transci.2016.10.011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10027
  • [Journal Article] Internal tandem duplication of FLT3 deregulates proliferation2016

    • Author(s)
      Tomohiro Hirade, Mariko Abe Chie Onishi, Takeshi Taketani, Seiji Yamaguchi, Seiji Fukuda
    • Journal Title

      International Journal of Hematology

      Volume: 103 Issue: 1 Pages: 95-106

    • DOI

      10.1007/s12185-015-1908-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461593, KAKENHI-PROJECT-15K19616, KAKENHI-PROJECT-16K10027
  • [Journal Article] Internal Tandem Duplication in FLT3 Attenuates Proliferation and Regulates Resistance to the FLT3 Inhibitor AC220 by Modulating p21Cdkn1a and Pbx1 in Hematopoietic Cells2016

    • Author(s)
      Abe M, Pelus LM, Singh P, Hirade T, Onishi C, Purevsuren J, Taketani T, Yamaguchi S, Fukuda S
    • Journal Title

      PLOS One

      Volume: 11 Issue: 7 Pages: 1-26

    • DOI

      10.1371/journal.pone.0158290

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25461593, KAKENHI-PROJECT-16K10027, KAKENHI-PROJECT-15K19616
  • [Journal Article] Ex Vivo Expanded Allogeneic Mesenchymal Stem Cells with Bone Marrow Transplantation Improved Osteogenesis in Infants with Severe Hypophosphatasia2015

    • Author(s)
      Taketani T, Oyama C, Mihara A, Tanabe Y, Abe M, Hirade T, Yamamoto S, Bo R, Kanai R, Tadenuma T, Michibata Y, Yamamoto S, Hattori M, Katsube Y, Ohnishi H, Sasao M, Oda Y, Hattori K, Yuba S, Ohgushi H, Yamaguchi S
    • Journal Title

      Cell Transplant.

      Volume: 24 Issue: 10 Pages: 1931-1943

    • DOI

      10.3727/096368914x685410

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Journal Article] Cytogenetics and clinical features of pediatric myelodysplastic syndrome in Japan.2014

    • Author(s)
      Moriwaki K, Manabe A, Taketani T, Kikuchi A, Nakahata T, Hayashi Y
    • Journal Title

      Int J Hematol.

      Volume: 100 Issue: 5 Pages: 478-484

    • DOI

      10.1007/s12185-014-1674-z

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24591550, KAKENHI-PROJECT-25461611, KAKENHI-PROJECT-26461598, KAKENHI-PROJECT-26670498
  • [Journal Article] Ectopic Neuroblastoma in Monozygotic Twins With Different Ages of Onset : Possible Twin-to-Twin Metastasis In Utero With Distinct Genetic Alterations After Birth2014

    • Author(s)
      Taketani T, Takita J, Ueyama J, Kanai R, Kumori K, Maruyama R, Hayashi K, Ogawa S, Fukuda S, Yamaguchi S
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 36 Issue: 2 Pages: 166-168

    • DOI

      10.1097/mph.0b013e318290c686

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21249085, KAKENHI-PROJECT-23390269, KAKENHI-PROJECT-24591550, KAKENHI-PROJECT-24659491, KAKENHI-PROJECT-26293242, KAKENHI-PROJECT-26670493
  • [Journal Article] Internal Tandem Duplication of Mutations in Flt3 Augment Chemotaxis by Blocking the Down-regulation of Rho-Associated Kinase via CXCL12/CXCR4 signaling axis.2014

    • Author(s)
      Onishi C, Mori-Kimachi S, Hirade T, Abe M, Taketani T, Suzumiya J, Sugimoto T, Yamaguchi S, Kapur R, Fukuda S
    • Journal Title

      J Biol Chem

      Volume: 289 Issue: 45 Pages: 31053-31065

    • DOI

      10.1074/jbc.m114.568287

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24591550, KAKENHI-PROJECT-25461593
  • [Journal Article] Therapy-related Ph+ leukemia after both bone marrow and mesenchymal stem cell transplantation for hypophosphatasia.2013

    • Author(s)
      Taketani T, Kanai R, Abe M, Mishima S, Tadokoro M, Katsube Y, Yuba S, Ogushi H, Fukuda S, Yamaguchi S.
    • Journal Title

      Pediatr Int

      Volume: 55 Issue: 3

    • DOI

      10.1111/ped.12012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591550
  • [Journal Article] 皮膚限局型未分化大細胞型リンパ腫の小児例2013

    • Author(s)
      斎藤敦郎、竹谷健、金井理恵、金子栄、澄川靖之、三原綾、森田栄伸、山口清次
    • Journal Title

      日本小児血液がん学会雑誌

      Volume: 50 Pages: 237-242

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591550
  • [Journal Article] Low-density lipoprotein as a biomarker for the mobilization of hematopoietic stem cells in peripheral blood.2013

    • Author(s)
      Ishihara T, Mishima S, Kodama R, Yoshino I, Adachi E, Suyama T, Shibata H, Taketani T, Nagai A
    • Journal Title

      Transfus Apher Sci

      Volume: 49 Issue: 3 Pages: 539-541

    • DOI

      10.1016/j.transci.2013.07.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591550
  • [Journal Article] A Case With Sacrococcygeal Primitive Myxoid Mesenchymal Tumor of Infancy : A Case Report and Review of the Literature2013

    • Author(s)
      Saito A, Taketani T, Kanai R, Kanagawa T, Kumori K, Yamamoto N, Ishikawa N, Takita J, Yamaguchi S
    • Journal Title

      J Pediatr Hematol Oncol

      Volume: 35 Issue: 7 Pages: e280-e282

    • DOI

      10.1097/mph.0b013e31829182bb

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249085, KAKENHI-PROJECT-23390269, KAKENHI-PROJECT-24591550, KAKENHI-PROJECT-24659491
  • [Journal Article] Childhood acute myeloid leukemia with bone marrow eosinophilia caused by t(16;21)(q24;q22)2012

    • Author(s)
      Kawashima N, Shimada A, Taketani T, Hayashi Y, Yoshida N, Matsumoto K, Takahashi Y, Kojima S, Kato K
    • Journal Title

      Int J Hematol

      Volume: 95 Issue: 5 Pages: 577-580

    • DOI

      10.1007/s12185-012-1044-7

    • NAID

      10030633418

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591171, KAKENHI-PROJECT-22659196, KAKENHI-PROJECT-23591536, KAKENHI-PROJECT-23591537, KAKENHI-PROJECT-23591560, KAKENHI-PROJECT-24390268, KAKENHI-PROJECT-24591550
  • [Journal Article] Survivin selectively modulates genes deregulated in human leukemia stem cells2011

    • Author(s)
      Fukuda S, Abe M, Onishi C, Taketani T, Purevsuren J, Yamaguchi S, Conway EM, Pelus LM
    • Journal Title

      Journal of Oncology

      Pages: 946936-946936

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Journal Article] High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes.2010

    • Author(s)
      Taketani T
    • Journal Title

      Leukemia

      Volume: 24巻 Pages: 1975-1977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Journal Article] High frequencies of simultaneous FLT3-ITD, WT1 and KIT mutations in hematological malignancies with NUP98-fusion genes2010

    • Author(s)
      Taketani T, Taki T, Nakamura T, Kobayashi Y, Ito E, Fukuda S, Yamaguchi S, Hayashi Y
    • Journal Title

      Leukemia

      Volume: 24 Pages: 1975-1977

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Journal Article] NUP98-NSD3 fusion gene in radiation-associated myelodysplastic syndrome with t(8;11)(p11;p15)and expression pattern of NSD family genes.2009

    • Author(s)
      Taketani T
    • Journal Title

      Cancer Genetics Cytogenetics 190

      Pages: 108-112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Journal Article] Mutations of GATA1,FLT3,MLL-partial tandem duplication,NRAS,and RUNX1 genes are not found in a 7-year-old Down syndrome patient with acute myeloid leukemia (FAB-M2) having a good prognosis.2008

    • Author(s)
      Kawamura M,Kaku H,Taketani T,Taki T,Shimada A,Hayashi Y
    • Journal Title

      Cancer Genet Cytogenet 180

      Pages: 74-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Journal Article] Tandem duplications of MLL and FLT3 are correlated with poor prognoses in pediatric acute myeloid leukemia : a study of the Japanese childhood AML Cooperative Study Group2008

    • Author(s)
      Shimada A,Taki T,Tabuchi K,Taketani T,Hanada R, Tawa A,Tsuchida M,Horibe K,Tsukimoto I,Hayashi Y
    • Journal Title

      Pediatr Blood Cancer 50

      Pages: 264-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Journal Article] MNX1-ETV6 fusion gene in an acute megakaryoblastic leukemia and expression of the MNX1 gene in leukemia and normal B cell lines.2008

    • Author(s)
      Taketani T,Taki T,Sako M,Ishii T,Yamaguchi S,Hayashi Y
    • Journal Title

      Cancer Genet Cytogenet 186

      Pages: 115-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Journal Article] Induction of differentiation of myeloid leukemia cells in primary culture in response to lithocholic acid acetate,a bile acid derivative,and cooperative effects with another differentiation inducer,cotylenin A.2008

    • Author(s)
      Horie A,Akimoto M,Tsumura H,Makishima M,Taketani T,Yamaguchi S,Honma Y
    • Journal Title

      Leuk Res 32

      Pages: 1112-1123

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Journal Article] MNX1-ETV6 fusion gene in an acute megakaryoblastic leukemia and expression of the MNX1 gene in leukemia and normal B cell lines2008

    • Author(s)
      Taketani T
    • Journal Title

      Cancer Genetics Cytogenetics 186

      Pages: 115-119

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Journal Article] AML1 Mutation and FLT3-internal Tandem Duplication in Leukemia Transformed From Myelodysplastic Syndrome2007

    • Author(s)
      Shimada A,Taketani T,Kikuchi A,Hanada R, Arakawa H,Kimura H,Chen Y,Hayashi Y
    • Journal Title

      J Pediatr Hematol Oncol 29

      Pages: 666-667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Journal Article] FLT3 mutations in the activation loop of tyrosine kinase domain are frequently found in infant ALL with MLL rearrangements and pediatric ALL with hyperdiploidy2004

    • Author(s)
      Taketani T
    • Journal Title

      Blood 103-3

      Pages: 1085-1088

    • Data Source
      KAKENHI-PROJECT-15790529
  • [Journal Article] HLXB9-ETV6 fusion gene in an acute megakaryoblastic leukemia patient and expression of the HLXB9 gene in leukemia and normal B cell lines

    • Author(s)
      Takeshi Taketani
    • Journal Title

      Haematologia (発表予定)

    • Data Source
      KAKENHI-PROJECT-18790720
  • [Patent] ミトコンドリア病 治療用組成物2023

    • Inventor(s)
      竹谷健、杨嘉豪、松崎有未、陶山隆史
    • Industrial Property Rights Holder
      竹谷健、杨嘉豪、松崎有未、陶山隆史
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Overseas
    • Data Source
      KAKENHI-PROJECT-23K27567
  • [Presentation] MELAS-derived neuron functionally improve by mitochondrial transfer from Rapidly Expanding Cell, REC2024

    • Author(s)
      LU LIU, Jiahao Yang, Yoshinori Otani, Takahiro Shiga, Akihiro Yamaguchi, Yumi Matsuzaki, Wado Akamatsu, Masashi Fujitani, Takeshi Taketani
    • Organizer
      第23回日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-23K27567
  • [Presentation] 東アジア諸国のタンデムマスによる新生児スクリーニング結果の比較2022

    • Author(s)
      山口清次、山田 健治, 長谷川 有紀、小林 弘典, 但馬剛, 竹谷 健
    • Organizer
      第49回日本マススクリーニング学会
    • Data Source
      KAKENHI-PROJECT-19K08347
  • [Presentation] 検量線を用いたアシルカルニチン分析法における血清・血漿検体のアシルカルニチンの安定性に関する検討2020

    • Author(s)
      大澤好充、小林 弘典, 野津 吉友, 山田 健治, 長谷川 有紀, 山口 清次, 竹谷 健
    • Organizer
      第47回日本マススクリーニング学会
    • Data Source
      KAKENHI-PROJECT-19K08347
  • [Presentation] アジア諸国のタンデムマスによる新生児スクリーニング結果の比較2020

    • Author(s)
      山口清次、山田 健治, 長谷川 有紀、小林 弘典, 但馬剛, 竹谷 健
    • Organizer
      第47回日本マススクリーニング学会
    • Data Source
      KAKENHI-PROJECT-19K08347
  • [Presentation] Diversity of disease spectrum of the MS/MS screening targets in Asia2019

    • Author(s)
      8) Yamaguchi S, Shibata N, Hasegawa Y, Kobayashi H, Yamada K, Ohsawa Y, Fukuda S, Taketani
    • Organizer
      第61回先天代謝異常学会アジアセッション
    • Data Source
      KAKENHI-PROJECT-19K08347
  • [Presentation] 先天性遺伝性疾患に対する再生医療2016

    • Author(s)
      竹谷健
    • Organizer
      第68回中国四国小児科学会
    • Place of Presentation
      香川
    • Year and Date
      2016-10-29
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Presentation] 間葉系幹細胞を用いた新たな治療~白血病から遺伝子疾患まで~2016

    • Author(s)
      竹谷健
    • Organizer
      小児白血病カンファレンス
    • Place of Presentation
      岡山
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Presentation] 間葉系幹細胞を用いた先天性骨系統疾患に対する骨再生2016

    • Author(s)
      竹谷健
    • Organizer
      第35回日本運動器移植・再生医学研究会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Presentation] 間葉系幹細胞移植による骨再生2016

    • Author(s)
      竹谷健、松崎有未、弓場俊輔、大串始
    • Organizer
      第15回日本再生医療学会
    • Place of Presentation
      大阪
    • Year and Date
      2016-03-17
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Presentation] Allogeneic Mesenchymal Stem Cell and Bone Marrow Transplantation Improved Osteogenesis in Patients with severe Hypophosphatasia2015

    • Author(s)
      Taketani T, Oyama C, Tanabe Y, Yamamoto K, Kanai R, Yamaguchi S, Hattori M, Oda Y, Yuba S, Ohgushi H.
    • Organizer
      The 11th Asian Society for Pediatric Research
    • Place of Presentation
      大阪
    • Year and Date
      2015-04-15
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Presentation] 先天性骨代謝疾患に対する同種間葉系幹細胞を用いた骨再生治療.シンポジウム2「明るい未来にむけた先天代謝異常症の再生治療の可能性」2015

    • Author(s)
      竹谷健、山口清次
    • Organizer
      第57回日本先天代謝異常学会
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-12
    • Invited
    • Data Source
      KAKENHI-PROJECT-26293251
  • [Presentation] Treatment approach for hypophosphatasia via genetically modified patient’s MSCs derived from iPS cells2015

    • Author(s)
      Yasuaki Oda, Mika Tadokoro, Shunsuke Yuba, Hajime Ohgushi, Seiji Yamaguchi, and Takeshi Taketani
    • Organizer
      第11回 ALPS研究会
    • Place of Presentation
      日本女子大学(東京都文京区目白台2-8-1)
    • Year and Date
      2015-07-18
    • Data Source
      KAKENHI-PROJECT-15K21176
  • [Presentation] 骨髄性造血器腫瘍の遺伝子解析の検討2011

    • Author(s)
      竹谷健、服部美保、日向瑞貴、安部真理子、大西千恵、福田誠司
    • Organizer
      第42回島根造血器腫瘍研究会
    • Place of Presentation
      ホテル武志山荘(島根県出雲市)
    • Year and Date
      2011-07-29
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] The Concurrent Mutations in Hematological Malignancies with NUP98-Fusion Genes are Associated with Clinical Prognosis of the Patients2011

    • Author(s)
      Taketani T
    • Organizer
      53rd American Society of Hematology Annual Meeting
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] The Concurrent Mutations in Hematological Malignancies with NUP98-Fusion Genes are Associated with Clinical Prognosis of the Patients2011

    • Author(s)
      Takeshi Taketani, Tomohiko Taki, Miz uki Hyuga, Chie Onishi, Seiji Fukuda, Seiji Yamaguchi, Yasuhide Hayashi
    • Organizer
      53rd American Society of Hematology Annual Meeting
    • Place of Presentation
      San diego, USA
    • Year and Date
      2011-12-10
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] 染色体11p15異常を有する造血器腫瘍における遺伝子変異と臨床像の関連2011

    • Author(s)
      竹谷健、滝智彦、日向瑞貴、安部真理子、福田誠司、山口清次、林泰秀
    • Organizer
      第53回日本小児血液・がん学会
    • Place of Presentation
      ベイシア文化ホール(群馬県高崎市)
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] 染色体11p15異常を有する造血器腫瘍における遺伝子変異と臨床像の関連2011

    • Author(s)
      竹谷健
    • Organizer
      第53回日本小児血液・がん学会
    • Place of Presentation
      ベイシア文化ホール(群馬県前橋市)
    • Year and Date
      2011-11-25
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] NUP98遺伝子再構成を有する小児造血器腫瘍に同定された遺伝子変異とその臨床的意義2009

    • Author(s)
      竹谷健
    • Organizer
      第51回日本小児血液学会
    • Place of Presentation
      東京ベイホテル東急(千葉)
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] Clinical significance of somatic mutations in hematological malignancies with NUP98-fusion genes2009

    • Author(s)
      Takeshi Taketani, Tomohiko Taki, Seiji Fukuda, Seiji Yamaguchi, Yasuhide Hayashi
    • Organizer
      The 71st Annual meeting of the Japanese society of Hematology
    • Place of Presentation
      京都国際会館(京都市)
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] Clinical significance of somatic mutations in hematological malignancies with NUP98-Lfusion genes.2009

    • Author(s)
      Taketani T
    • Organizer
      The 71st Annual meeting of the Japanese society of Hematology.
    • Place of Presentation
      Kyoto International Conference Center(Kyoto)
    • Year and Date
      2009-10-23
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] NUP98遺伝子再構成を有する小児造血器腫瘍に同定された遺伝子変異とその臨床的意義2009

    • Author(s)
      竹谷健、滝智彦、山口清次、林泰秀
    • Organizer
      NUP98遺伝子再構成を有する小児造血器腫瘍に同定された遺伝子変異とその臨床的意義
    • Place of Presentation
      東京ベイホテル東急(千葉県浦安市)
    • Year and Date
      2009-11-28
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] High frequencies of FLT3-ITD, WT1, and KIT, mutations in hematologic malignancies with NUP98-fusion genes2009

    • Author(s)
      Takeshi Taketani, Tomohiko Taki, Mariko Abe, Chie Onishi, Seiji Fukuda, Seiji Yamaguchi, Yasuhide Hayashi
    • Organizer
      51th American Society of Hematology
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-06
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] High frequencies of FLT3-ITD, WT1, and KIT, mutations in hematologic malignancies with NUP98-fusion genes.2009

    • Author(s)
      Taketani T
    • Organizer
      51th American Society of Hematology
    • Place of Presentation
      New Orleans, USA
    • Year and Date
      2009-12-06
    • Data Source
      KAKENHI-PROJECT-21790989
  • [Presentation] Correlation of FLT3-ITD and KIT mutations with clinical features in myeloid malignancies with NUP98-HOX fusion genes2008

    • Author(s)
      Taketani T
    • Organizer
      50th American Society of Hematology
    • Place of Presentation
      San Francisico, USA
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Presentation] Correlation of FLT3-ITD and KIT mutations with clinical features in myeloid malignancies with NUP98-HOX fusion genes2008

    • Author(s)
      Takeshi Taketani,Tomohiko Taki,Seiji Fukuda,Seiji Yamaguchi Yasuhide Hayashi
    • Organizer
      50th American Society of Hematology,San Francisico
    • Place of Presentation
      USA
    • Data Source
      KAKENHI-PROJECT-18790720
  • [Presentation] Flt3/ITD Enhances Hematopoietic Cell Migration towards Chemokine CCL2 Independent of Blocking the Negative Feedback Mechanism on Rho-Associated Kinase.

    • Author(s)
      Seiji Fukuda, Chie Onishi, Tomohiro Hirade, Mariko Abe, Takeshi Taketani, Seiji Yamaguchi.
    • Organizer
      56rd American Society of Hematology Annual Meeting
    • Place of Presentation
      The Moscone Center (San Francisco, USA)
    • Year and Date
      2014-12-06 – 2014-12-09
    • Data Source
      KAKENHI-PROJECT-24591550
  • [Presentation] Myeloid Cells having NUP98-HOX Fusion Genes with Simultaneous FLT3, NRAS, or WT1 Mutations Confer Growth Advantage, Inhibits Differeniation/Apoptosis, and Augment Self-Renewal.

    • Author(s)
      Takeshi Taketani, Miho Hattori, Mariko Abe, Tomohiro Hirade, Seiji Fukuda, Seiji Yamaguchi.
    • Organizer
      56rd American Society of Hematology Annual Meeting
    • Place of Presentation
      The Moscone Center (San Francisco, USA)
    • Year and Date
      2014-12-06 – 2014-12-09
    • Data Source
      KAKENHI-PROJECT-24591550
  • [Presentation] Flt3/ITD変異はケモカインCCL2に対する造血細胞遊走を亢進する

    • Author(s)
      福田誠司、平出智裕、安部真理子、竹谷 健、山口清次.
    • Organizer
      第56回日本小児血液がん学会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-24591550
  • [Presentation] NUP98-HOX融合遺伝子と協調する遺伝子変異との白血病発症メカニズムの解析.

    • Author(s)
      竹谷健、服部美保、安部真理子、平出智裕、福田誠司、山口清次.
    • Organizer
      第56回日本小児血液がん学会
    • Place of Presentation
      岡山コンベンションセンター(岡山市)
    • Year and Date
      2014-11-28 – 2014-11-30
    • Data Source
      KAKENHI-PROJECT-24591550
  • 1.  MATSUZAKI Yumi (50338183)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  Nagamura-Inoue Tokiko (70240736)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  HIROSE Jun (00456112)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Oda Yasuaki (70602473)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  Yamaguchi Seiji (60144044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 6.  竹谷 英之 (90206996)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 7.  福田 誠司 (30273147)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  大谷 嘉典 (30815973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  藤谷 昌司 (40376372)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  赤松 和土 (60338184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 11.  山田 健治 (70624930)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 12.  MUKAI Takeo
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  MORI Yuka
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  Hori Akiko
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MOCHIDA Miho
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  NAGASE Mayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NAITOU Mayumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SUYAMA Takashi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  YANG JIAHAO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  KOBAYASHI Hironori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 21.  林 泰秀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  滝田 順子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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