Mizoguchi Hirokazu 溝口広一

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MIZOGUCHI Hirokazu 溝口広一

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Researcher Number	30360069
Other IDs
Affiliation (Current)	2025: 東北医科薬科大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 東北医科薬科大学, 薬学部, 教授 2016 – 2017: 東北医科薬科大学, 薬学部, 教授 2016: 東北医科薬科大学, 薬学部, 准教授 2006 – 2015: Tohoku Pharmaceutical University, Department of Physiology and Anatomy, Associate Professor 2004 – 2006: 東北薬科大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Pain science / Basic Section 47040:Pharmacology-related / 疼痛学 / Biological pharmacy Except Principal Investigator Pain science / Pain science / Drug development chemistry / Biological pharmacy / 疼痛学
Keywords	Principal Investigator μ受容体 / ジーンセラピー / 難治性疼痛 / 鎮痛薬 / 末梢性作用薬 / 末梢作用 / κオピオイド受容体 / 末梢性作用 / μオピオイド受容体 / 難治性掻痒 … More / NMDA受容体 / Methadone / Morphine / 多発性硬化症疼痛 / 疼痛 / 多発性硬化症 / 産生遺伝子 / エンドモルフィン / 副作用 / 同定 / オピオイド / 内因性ペプチド … More Except Principal Investigator 脊髄 / スプライスバリアント / μ受容体 / オピオイドペプチド / ジーンセラピー / オピオイド / 難治性疼痛 / モルヒナン / メサドン / Opioid Peptides / Splice Variants / Receptor Expressed Cell / Opioid Receptor / 発現細胞 / オピオイド受容体 / 掻痒 / NMDA受容体 / ポリアミン / ヒスタミン / マイクロダイアリシス / 受容体 / 疼痛伝達物質 / 神経障害性疼痛 / 鎮痛 / 癌性疼痛 / 内因性ペプチド / 鎮痛薬 / 神経性御 / 神経制御 / 鎮痛作用 / 疼痛伝達 / ノシセプチン Less

Development of specific therapeutic agents for intractable pruritus without side effectsPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hirokazu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Methadone-used new therapy for morphine-resistant intractable painPrincipal Investigator
- Principal Investigator
  
  Mizoguchi Hirokazu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Medical and Pharmaceutical University
Development of selective agonists for the morphine-insensitive opioid mu receptor splice variants
- Principal Investigator
  
  Fujii Hideaki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kitasato University
Investigation for the histamine-related mechanism of neuropathic pain and development of its therapy
- Principal Investigator
  
  SAKURADA Shinobu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Pharmaceutical University
The mechanism for multiple sclerosis-related pain and its new therapyPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI HIROKAZU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Pharmaceutical University
Investigation for the mechanism of neuropathic pain on spinal pain transmission.
- Principal Investigator
  
  WATANABE Chizuko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Pharmaceutical University
Development of new therapy for neuropathic cancer pain
- Principal Investigator
  
  SAKURADA Shinobu
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Tohoku Pharmaceutical University
Development of the gene therapy against the morphine-resistant intractable pain using endomorphin precursorPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Hirokazu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  疼痛学
- Research Institution
  Tohoku Pharmaceutical University
Development of new analgesics and therapy for intractable pain
- Principal Investigator
  
  SAKURADA Shinobu
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Pharmaceutical University
Study for reciprocal double effects of nociceptin on spinal pain transmission.
- Principal Investigator
  
  WATANABE Chizuko
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Tohoku Pharmaceutical University
Identification of novel endogenous mupioid peptide and characterization of its physiological rolesPrincipal Investigator
- Principal Investigator
  
  MIZOGUCHI Hirokazu
- Project Period (FY)
  2005 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku Pharmaceutical University
Molecular pharmacological study for characterization of new identified iropioid receptor subclass
- Principal Investigator
  
  SAKURADA Shinobu
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku Pharmaceutical University

[Book] 疾患薬理学2016
- Author(s)
  溝口広一
- Total Pages
  862
- Publisher
  Neo Medical
- Data Source
  KAKENHI-PROJECT-15K08678
[Book] Aromatherapy: Basic Mechanisms and Evidence Based Clinical Use2015
- Author(s)
  Laura Rombola, Luigi Antonio Morrone, Chizuko Watanabe, Hirokazu Mizoguchi, Tsukasa Sakurada, Laura Berliocchi, Maria Tiziana Corasaniti, Giacinto Bagetta, and Shinobu Sakurada
- Total Pages
  461
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-15K08678
[Book] Aromatherapy: Basic Mechanisms and Evidence Based Clinical Use2015
- Author(s)
  Laura Rombola, Luigi Antonio Morrone, Chizuko Watanabe, Hirokazu Mizoguchi, Tsukasa Sakurada, Laura Berliocchi, Maria Tiziana Corasaniti, Giacinto Bagetta, Shinobu Sakurada
- Total Pages
  461
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-25460725
[Book] 薬局６2013
- Author(s)
  佐野元彦、溝口広一、高瀬久光
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-24590731
[Book] トワイクロス先生のがん緩和ケア処方薬2013
- Author(s)
  溝口広一
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24590731
[Book] Handbook of Biological Active Peptides 2nd Edition2013
- Author(s)
  H. Mizoguchi, T. Sakurada, S. Sakurada
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-22600009
[Book] 緩和医療薬学2013
- Author(s)
  溝口広一
- Total Pages
  71
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-24590731
[Book] Handbook of Biological Active Peptides 2nd Edition2012
- Author(s)
  Hirokazu Mizoguchi
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-24590731
[Book] Neuropeptides in Neuroprotection and Neuroregeneration2012
- Author(s)
  C. Sakurada, H. Mizoguchi, T. Komatsu, S. Sakurada, T. Sakurada
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-22600009
[Book] Handbook of Biological Active Peptides 2nd Edition2012
- Author(s)
  Hirokazu Mizoguchi
- Publisher
  Elsevier
- Data Source
  KAKENHI-PROJECT-22600009
[Book] HERVAL MEDICINES : Development and Validation of Plant-Derived Medicines for Human Health2011
- Author(s)
  Hirokazu Mizoguchi, 他
- Publisher
  CRC Press
- Data Source
  KAKENHI-PROJECT-21600013
[Book] HERVAL MEDICINES: Development and Validation of Plant-Derived Medicines for Human Health2011
- Author(s)
  T. Sakurada, H. Mizoguchi, S. Katsuyama, T. Komatsu, H. Kuwahata, L. Rombola, G. Bagetta, M.T. Corasaniti, S. Sakurada
- Publisher
  CRC Pres
- Data Source
  KAKENHI-PROJECT-22600009
[Book] 安全性薬理試験マニュアル2009
- Author(s)
  溝口広一、櫻田忍
- Publisher
  エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-19603011
[Book] 生体の科学2009
- Author(s)
  溝口広一, 他
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21600013
[Book] 生体の科学602009
- Author(s)
  溝口広一、櫻田忍
- Publisher
  金原一郎記念医学医療振興財団/医学書院
- Data Source
  KAKENHI-PROJECT-19603011
[Book] 安全性薬理試験マニュアル(藤森観之助、橋本敬太郎、安東賢太郎編)
- Author(s)
  溝口広一、櫻田忍
- Publisher
  エル・アイ・シー(印刷中)
- Data Source
  KAKENHI-PROJECT-17590065
[Book] 生理活性ペプチドハンドブック(松尾壽之、南野直人編)
- Author(s)
  櫻田忍、溝口広一
- Publisher
  メデイカルドウ(印刷中)
- Data Source
  KAKENHI-PROJECT-17590065
[Book] 生理活性ペプチドハンドブック
- Author(s)
  櫻田忍、溝口広一
- Publisher
  メディカル・ドゥ(印刷中)
- Data Source
  KAKENHI-PROJECT-19603011
[Book] 安全性薬理試験マニュアル
- Author(s)
  溝口広一
- Publisher
  エル・アイ・シー(印刷中)
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] Synthesis of unnatural morphinan compounds to induce itch-like behaviors in mice: Towards the development of MRGPRX2 selective ligands2022
- Author(s)
  Iio Keita、Kutsumura Noriki、Nagumo Yasuyuki、Saitoh Tsuyoshi、Tokuda Akihisa、Hashimoto Kao、Yamamoto Naoshi、Kise Ryoji、Inoue Asuka、Mizoguchi Hirokazu、Nagase Hiroshi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 56 Pages: 128485-128485
- DOI
  10.1016/j.bmcl.2021.128485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05710, KAKENHI-PUBLICLY-20H04763, KAKENHI-ORGANIZER-21H05111, KAKENHI-PLANNED-21H05113, KAKENHI-PROJECT-21H04791, KAKENHI-PROJECT-21K06602
[Journal Article] Translational Value of the Transdermal Administration of Bergamot Essential Oil and of Its Fractions2022
- Author(s)
  Scuteri Damiana、Rombola Laura、Crudo Michele、Watanabe Chizuko、Mizoguchi Hirokazu、Sakurada Shinobu、Hamamura Kengo、Sakurada Tsukasa、Morrone Luigi Antonio、Tonin Paolo、Bagetta Giacinto、Corasaniti Maria Tiziana
- Journal Title
  
  Pharmaceutics
  
  Volume: 14 Issue: 5 Pages: 1006-1006
- DOI
  10.3390/pharmaceutics14051006
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06602, KAKENHI-PROJECT-21K11613
[Journal Article] Neuropharmacological properties of the essential oil of bergamot for the clinical management of pain-related BPSDs2018
- Author(s)
  Damiana Scuteri, Laura Rombola, Laura Tridico, Hirokazu Mizoguchi, Chizuko Watanabe, Tsukasa Sakurada, Shinobu Sakurada, Maria Tiziana Corasanit, Giacinto Bagetta, Luigi Antonio Morrone
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 印刷中 Issue: 20 Pages: 3764-3774
- DOI
  10.2174/0929867325666180307115546
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08678
[Journal Article] The involvement of spinal release of histamine on nociceptive behaviors induced by intrathecally administered spermine.2017
- Author(s)
  Mizoguchi H, Watanabe C, Hayashi T, Iwata Y, Watanabe H, Katsuyama S, Hamamura K, Sakurada T, Ohtsu H, Yanai K, Sakurada S.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 800 Pages: 9-15
- DOI
  10.1016/j.ejphar.2017.01.031
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06795, KAKENHI-PROJECT-15K08678
[Journal Article] Bergamot essential oil attenuates anxiety-like behaviour in rats2017
- Author(s)
  Laura Rombola, Laura Tridico, Damiana Scuteri, Tsukasa Sakurada, Shinobu Sakurada, Hirokazu Mizoguchi, Pinarosa Avato, Maria Tiziana Corasaniti, Giacinto Bagetta, Luigi Antonio Morrone
- Journal Title
  
  Molecules
  
  Volume: 22 Issue: 4 Pages: 614-614
- DOI
  10.3390/molecules22040614
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08678
[Journal Article] Opioids resistance in chronic pain management2017
- Author(s)
  Luigi A. Morrone, Damiana Scuteri, Laura Rombola, Hirokazu Mizoguchi, Giacinto Bagetta
- Journal Title
  
  Current Neuropharmacology
  
  Volume: 15 Issue: 3 Pages: 444-456
- DOI
  10.2174/1570159x14666161101092822
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08678
[Journal Article] Involvement of spinal glutamate in nociceptive behavior induced by intrathecal administration of hemokinin-1 in mice2016
- Author(s)
  Chizuko Watanabe, Hirokazu Mizoguchi, Giacinto Bagetta, Shinobu Sakurada
- Journal Title
  
  Neuroscience Letters
  
  Volume: 617 Pages: 236-239
- DOI
  10.1016/j.neulet.2016.02.027
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08678, KAKENHI-PROJECT-25460725
[Journal Article] Intrathecal morphine-3-glucuronide-induced nociceptive behavior via δ-2 opioid receptors in the spinal cord2016
- Author(s)
  Takaaki Komatsu, Soh Katsuyama, Hiroshi Nagase, Hirokazu Mizoguchi, Chikai Sakurada, Minoru Tsuzuki, Shinobu Sakurada, Tsukasa Sakurada
- Journal Title
  
  Pharmacology Biochemistry & Behavior
  
  Volume: 140 Pages: 68-74
- DOI
  10.1016/j.pbb.2015.10.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08678, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-ORGANIZER-15H05935, KAKENHI-PLANNED-15H05942, KAKENHI-PROJECT-25460725
[Journal Article] Analgesic Effects of 1st Generation Anti-histamines in Mice2016
- Author(s)
  Mebae Takahashi, Kazuhiro Shima, Masahiro Tsuchiya, Yoshihiro Hagiwara, Hirokazu Mizoguchi, Shinobu Sakurada, Shunji Sugawara, Takuo Fujita, Takeshi Tadano, Makoto Watanabe, Satoshi Fukumoto, Yasuo Endo
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 39 Issue: 4 Pages: 620-624
- DOI
  10.1248/bpb.b15-00755
- NAID
  130005141684
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08678, KAKENHI-PROJECT-16K11580, KAKENHI-PROJECT-16K11611, KAKENHI-PROJECT-16K11672
[Journal Article] Differential alternation of the antinociceptive effect of narcotic analgesics on the inflammatory pain state2014
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Neuroscience Letters
  
  Volume: 560 Pages: 122-125
- DOI
  10.1016/j.neulet.2013.12.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590718, KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Potential Involvement of <i>μ</i>-Opioid Receptor Dysregulation on the Reduced Antinociception of Morphine in the Inflammatory Pain State in Mice2014
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Kumiko Takeda, Tsukasa Sakurada,Shinobu Sakurada
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 124 Issue: 2 Pages: 258-266
- DOI
  10.1254/jphs.13242FP
- NAID
  130003391472
- ISSN
  1347-8613, 1347-8648
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590718, KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Involvement of multipleμ-opioid receptor subtypes on the presynaptic or postsynaptic inhibition of spinal pain transmission2014
- Author(s)
  Hirokazu Mizoguchi, Hirokazu Takagi, Chizuko Watanabe, Akihiko Yonezawa, Takumi Sato, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Peptides
  
  Volume: 51 Pages: 15-25
- DOI
  10.1016/j.peptides.2013.10.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590718, KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Spinal ERK2 activation through δ2-opioid receptors contributes to nociceptive behavior induced by intrathecal injection of leucine-enkephalin2014
- Author(s)
  Takaaki Komatsu, Soh Katsuyama, Hirokazu Mizoguchi, Chikai Sakurada, Minoru Tsuzuki, Shinobu Sakurada, Tsukasa Sakurada
- Journal Title
  
  Peptides
  
  Volume: 54 Pages: 131-139
- DOI
  10.1016/j.peptides.2014.01.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Involvement of peripheral cannabinoid and opioid receptors in β-caryophyllene-induced antinociception2013
- Author(s)
  Soh Katsuyama, Hirokazu Mizoguchi, Hikari Kuwahata, Takaaki Komatsu, Kohshi Nagaoka, Hitoshi Nakamura, Giacinto Bagetta, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  European Journal of Pain
  
  Volume: 17 Issue: 5 Pages: 664-675
- DOI
  10.1002/j.1532-2149.2012.00242.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Involvement of spinal release ofα-neo-endorphin on the antinociceptive effect of TAPA2013
- Author(s)
  Hirokazu Mizoguchi, Takashi Kon-no, Hiroyuki Watanabe, Chizuko Watanabe, Akihiko Yonezawa, Takumi Sato, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Peptides
  
  Volume: 50 Pages: 139-144
- DOI
  10.1016/j.peptides.2013.10.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590718, KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Distinct physiological role of amidino-TAPA-sensitive and DAMGO-insensitive μ-opioid receptor splice variants in the mouse spinal cord2013
- Author(s)
  Hirokazu Mizoguchi, Chizuko Watanabe, Takayuki Higashiya, Satoshi Takeda, Kaori Moriyama, Akihiko Yonezawa, Takashi Kon-no, Hirokazu Takagi, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Eur. J. Pharmacol.
  
  Volume: 711 Issue: 1-3 Pages: 80-86
- DOI
  10.1016/j.ejphar.2013.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590718, KAKENHI-PROJECT-24590731, KAKENHI-PROJECT-25460725
[Journal Article] Non-opioid nociceptive activity of human dynorphin mutants that cause neurodegenerative disorder spinocerebellar ataxia type 232012
- Author(s)
  H. Watanabe, H. Mizoguchi, D.S. Verbeek, A. Kuzmin, F. Nyberg, O. Krishtal, S. Sakurada, G. Bakalkin
- Journal Title
  
  Peptides
  
  Volume: 35 Issue: 2 Pages: 306-310
- DOI
  10.1016/j.peptides.2012.04.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009, KAKENHI-PROJECT-24590731
[Journal Article] New vistas in opioid control of pain2012
- Author(s)
  H. Mizoguchi, C. Watanabe, T. Sakurada, S. Sakurada
- Journal Title
  
  Curr. Opin. Pharmacol
  
  Volume: 12 Issue: 1 Pages: 87-91
- DOI
  10.1016/j.coph.2011.11.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009
[Journal Article] New vistas in opioid control of pain2012
- Author(s)
  H. Mizoguchi, C. Watanabe, T. Sakurada, S. Sakurada
- Journal Title
  
  Curr. Opin. Pharmacol
  
  Volume: 12 Issue: 1 Pages: 87-91
- DOI
  10.1016/j.coph.2011.10.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009, KAKENHI-PROJECT-23590718
[Journal Article] The involvement of the spinal release of glutamate and nitric oxide in peripheral noxious stimulation-induced pain-related behaviors -Study in mouse spinal microdialysis-2012
- Author(s)
  C. Watanabe, H. Mizoguchi, G. Bagetta, S. Sakurada
- Journal Title
  
  Neurosci. Lett
  
  Volume: 515 Issue: 2 Pages: 111-114
- DOI
  10.1016/j.neulet.2012.02.091
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009, KAKENHI-PROJECT-23590718, KAKENHI-PROJECT-24590731
[Journal Article] Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine2011
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Peptides
  
  Volume: 32 Pages: 421-427
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009
[Journal Article] Involvement of glial cells in the nociceptive behaviors induced by a high-dose of histamine administered intrathecally2011
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur.J.Pharmacol.
  
  Volume: 653 Pages: 21-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] Antinociceptive effects of spinally administered nociceptin/orphanin FQ and its N-terminal fragments on capsaicin-induced nociception2011
- Author(s)
  S. Katsuyama, H. Mizoguchi, T. Komatsu, C. Sakurada, M. Tsuzuki, S. Sakurada, T. Sakurada
- Journal Title
  
  Peptides
  
  Volume: 32 Issue: 7 Pages: 1530-1535
- DOI
  10.1016/j.peptides.2011.05.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] Involvement of mouse μ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA2011
- Author(s)
  H. Mizoguchi, C. Watanabe, T. Higashiya, S. Takeda, K. Moriyama, A. Yonezawa, T. Sato, T. Komatsu, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol
  
  Volume: 651 Issue: 1-3 Pages: 66-72
- DOI
  10.1016/j.ejphar.2010.10.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009
[Journal Article] Involvement of glial cells in the nociceptive behaviors induced by a high-dose of histamine administered intrathecally2011
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur.J.Pharmacol.
  
  Volume: 653 Pages: 21-25
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009
[Journal Article] Dermorphin tetrapeptide analogs as potent and long-lasting analgesics with pharmacological profiles distinct from morphine2011
- Author(s)
  H. Mizoguchi, G. Bagetta, T. Sakurada, S. Sakurada
- Journal Title
  
  Peptides
  
  Volume: 32 Issue: 2 Pages: 421-427
- DOI
  10.1016/j.peptides.2010.11.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] Inhibition of ERK phosphorylation by substance P N-terminal fragment decreases capsaicin-induced nociceptive response2011
- Author(s)
  T. Komatsu, H. Mizoguchi, M. Sasaki, C. Sakurada, M. Tsuzuki, S. Sakurada, T. Sakurada
- Journal Title
  
  Neuropharmacology
  
  Volume: 61 Issue: 4 Pages: 608-613
- DOI
  10.1016/j.neuropharm.2011.04.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] Partial involvement of NMDA receptors and glial cells in the nociceptive behaviors induced by intrathecally administered histamine2011
- Author(s)
  H. Mizoguchi, T. Komatsu, Y. Iwata, C. Watanabe, H. Watanabe, T. Orito, S. Katsuyama, A. Yonezawa, K. Onodera, T. Sakurada, S. Sakurada
- Journal Title
  
  Neurosci. Lett
  
  Volume: 495 Issue: 2 Pages: 83-87
- DOI
  10.1016/j.neulet.2011.02.038
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009, KAKENHI-PROJECT-23590718
[Journal Article] Intraplantar injection of bergamot essential oil induces peripheral antinociception mediated by opioid mechanism2011
- Author(s)
  T. Sakurada, H. Mizoguchi, H. Kuwahata, S. Katsuyama, T. Komatsu, L. A. Morrone, M. T. Corasaniti, G. Bagetta, S. Sakurada
- Journal Title
  
  Pharmacol. Biochem. Behav
  
  Volume: 97 Issue: 3 Pages: 436-443
- DOI
  10.1016/j.pbb.2010.09.020
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] Involvement of mouseμ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA2011
- Author(s)
  H. Mizoguchi, C. Watanabe, T. Higashiya, S. Takeda, K. Moriyama, A. Yonezawa, T. Sato, T. Komatsu, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol
  
  Volume: 651 Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] Involvement of mouse μ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA2011
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur.J.Pharmacol.
  
  Volume: 651 Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22600009
[Journal Article] Involvement of mouse μ-opioid receptor splice variants in the spinal antinociception induced by the dermorphin tetrapeptide analog amidino-TAPA2011
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur.J.Pharmacol.
  
  Volume: 651 Pages: 66-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] Involvement of glial cells in the nociceptive behaviors induced by a high-dose of histamine administered intrathecally2011
- Author(s)
  H. Mizoguchi, T. Komatsu, Y. Iwata, C. Watanabe, H. Watanabe, T. Orito, S. Katsuyama, A. Yonezawa, K. Onodera, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol
  
  Volume: 653 Issue: 1-3 Pages: 21-25
- DOI
  10.1016/j.ejphar.2010.10.096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] Lack of a rewarding effect and a locomotor-enhancing effect of the selective μ-opioid receptor agonist amidino-TAPA2010
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Psychopharmacology
  
  Volume: 212 Pages: 215-225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] Lack of a rewarding effect and a locomotor-enhancing effect of the selectiveμ-opioid receptor agonist amidino-TAPA2010
- Author(s)
  H. Mizoguchi, C. Watanabe, S. Osada, M. Yoshioka, Y. Aoki, S. Natsui, A. Yonezawa, S. Kanno, M. Ishikawa, T. Sakurada, S. Sakurada
- Journal Title
  
  Psychopharmacology
  
  Volume: 212 Issue: 2 Pages: 215-225
- DOI
  10.1007/s00213-010-1946-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] Characterization of intrathecally administered hemokinin-1-induced nociceptive behaviors in mice2010
- Author(s)
  C. Watanabe, H. Mizoguchi, A. Yonezawa, S. Sakurada
- Journal Title
  
  Peptides
  
  Volume: 31 Issue: 8 Pages: 1613-1616
- DOI
  10.1016/j.peptides.2010.04.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] The cannabinoid 1 receptor antagonist AM251 produces nocifensive behavior via activation of ERK signaling pathway2010
- Author(s)
  S. Katsuyama, H. Mizoguchi, T. Komatsu, K. Nagaoka, S. Sakurada, T. Sakurada
- Journal Title
  
  Neuropharmacology
  
  Volume: 59 Issue: 6 Pages: 534-541
- DOI
  10.1016/j.neuropharm.2010.07.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013, KAKENHI-PROJECT-22600009
[Journal Article] New therapy for neuropathic pain2009
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Int. Rew. Neurobiol. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613015
[Journal Article]2009
- Author(s)
  溝口広一
- Journal Title
  
  安全性薬理試験マニュアル(エル・アイ・シー)
  
  Pages: 258-264
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article]2009
- Author(s)
  溝口広一
- Journal Title
  
  生体の科学60((財)金原一郎記念医学医療振興財団/医学書院)
  
  Pages: 448-449
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] New therapy for neuropathic pain2009
- Author(s)
  H. Mizoguchi, C. Watanabe, A. Yonezawa, S. Sakurada
- Journal Title
  
  Int. Rev. Neurobiol
  
  Volume: 85 Pages: 249-260
- DOI
  10.1016/s0074-7742(09)85019-8
- ISBN
  9780123748935
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] New therapy for neuropathic pain2009
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Int.Rev.Neurobiol. 85
  
  Pages: 249-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21600013
[Journal Article] New therapy for neuropathic pain2009
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Int.Rev.Neurobiol. 85
  
  Pages: 249-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article]2009
- Author(s)
  溝口広一
- Journal Title
  
  生体の科学60((財)金原一郎記念医学医療振興財団/医学書院)
  
  Pages: 448-449
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] New therapy for neuropathic pain2009
- Author(s)
  H. Mizoguchi, C. Watanabe, A. Yonezawa, S. Sakurada
- Journal Title
  
  Int. Rev. Neurobiol 85
  
  Pages: 249-260
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] Intrathecal high-dose histamine induces spinally-mediated behavioral response through a polyamine site of NMDA receptors2008
- Author(s)
  Chizuko Watanabe, Tohru Orito, Hiroyuki Watanabe, Hirokazu Mizoguchi, Akihiko Yonezawa, Kazuhiko Yanai, Jalal I. Mobarakeh, Kenji Onodera, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Eur. J. Pharmacol. 581
  
  Pages: 54-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613015
[Journal Article] Possible involvement of dynorphin A release via μ_1-opioid receptor on supraspinal antinociception of endomorphin-2.2008
- Author(s)
  S. Sakurada, T. Sawai, H. Mizoguchi, H. Watanabe, C. Watanabe, A. Yonezawa, M. Morimoto, T. Sato, T. Komatsu, T. Sakurada
- Journal Title
  
  Peptides 29
  
  Pages: 1554-1560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Possible involvement of dynorphin A release viaμ1-opioid receptor on supraspinal antinociception of endomorphin-22008
- Author(s)
  S. Sakurada, T. Sawai, H. Mizoguchi, H. Watanabe, C. Watanabe, A. Yonezawa, M. Morimoto, T. Sato, T. Komatsu, T. Sakurada
- Journal Title
  
  Peptides 29
  
  Pages: 1554-1560
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] A Tyr-W-MIF-1 analog containing D-Pro2 discriminates among antinociception in mice mediated by different classes ofμ-opioid receptors2007
- Author(s)
  D. Nakayama, C. Watanabe, H. Watanabe, H. Mizoguchi, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol 563
  
  Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA.2007
- Author(s)
  H. Mizoguchi, C. Watanabe, H. Watanabe, K. Moriyama, B. Sato, K. Ohwada, A. Yonezawa, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol. 560
  
  Pages: 150-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Mechanisms responsible for the enhanced antinociceptive effects of μ-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain.2007
- Author(s)
  K. T. Sykes, S. R. White, R. W. Hurley, H Mizoguchi, L. F. Tseng, D. L. Hammond
- Journal Title
  
  J. Pharmacol. Exp. Ther. 322
  
  Pages: 813-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Mechanisms responsible for the enhanced antinociceptive effects ofμ-opioid receptor agonists in the rostral ventromedial medulla of male rats with persistent inflammatory pain2007
- Author(s)
  K.T. Sykes, S.R. White, R.W. Hurley, H Mizoguchi, L.F. Tseng, D.L. Hammond
- Journal Title
  
  J. Pharmacol. Exp. Ther. 322
  
  Pages: 813-821
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA2007
- Author(s)
  Hirokazu, Mizoguchi, et. al.
- Journal Title
  
  Eur. J. Pharmacol 560
  
  Pages: 150-159
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Involvement of endogenous opioid peptides in the antionciception induced by the novel dermorphin tetrapeptide analog amidino-TAPA2007
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur. J. Phatmacol. 560
  
  Pages: 150-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA2007
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur. J. Pharmacol. 560
  
  Pages: 150-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA2007
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur.J.Pharmacol 560
  
  Pages: 150-159
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Possible involvement of endogenous nociceptin/orphanin FQ in the pain- related behavioral responses induced by its own metabolite2007
- Author(s)
  Hiroyuki Watanabe, Hirokazu Mizoguchi, Tohru Orito, Sou Katsuyama, Akihiko Yonezawa, Chizuko Watanabe, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  nociceptin/orphanin FQ(14-17) 28
  
  Pages: 670-677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613015
[Journal Article] Intrathecal high-dose histamine induces spinally-mediated behavioral responses through a polyamine site of NMDA receptors2007
- Author(s)
  Chizuko Watanabe, Tohru Orito, Hiroyuki Watanabe, Hirokazu Mizoguchi, Akihiko Yonezawa, Kazuhiko Yanai, Jalal I. Mobarakeh, Kenji Onodera, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Eur. J. Pharmacol 581
  
  Pages: 54-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613015
[Journal Article] A Tyr-W-MIF-1 analog containing D-Pro^2 discriminates among antinociception in mice mediated by different classes of μ-opioid receptors.2007
- Author(s)
  D. Nakayama, C. Watanabe, H. Watanabe, H. Mizoguchi, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol. 563
  
  Pages: 109-116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Involvement of endogenous opioid peptides in the antinociception induced by the novel dermorphin tetrapeptide analog amidino-TAPA2007
- Author(s)
  H. Mizoguchi, C. Watanabe, H. Watanabe, K. Moriyama, B. Sato, K. Ohwada, A. Yonezawa, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol 560
  
  Pages: 150-159
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] Possible involvement of endogenous nociceptin/orphanin FQ in the painrelated behavioral responses induced by its own metabolite, nociceptin/ orphaninFQ(14-17)2007
- Author(s)
  Hiroyuki Watanabe, Hirokazu Mizoguchi, Tohru Orito, Sou Katsuyama, Akihiko Yonezawa, Chizuko Watanabe, Tsukasa Sakurada, Shinobu Sakurada
- Journal Title
  
  Peptides 28
  
  Pages: 670-677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613015
[Journal Article] Involvement of spinal μ_1-opioid receptors on the Tyr-D-Arg-Phe-sarcosin -induced antinociception2006
- Author(s)
  Hirokazu, Mizoguchi, et. al.
- Journal Title
  
  Eur. J. Pharmacol 540
  
  Pages: 67-72
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Contribution of spinal μ_1-opioid receptors and dynorphin B to the antinociception induced by Tyr-D-Arg-Phe-Sar2006
- Author(s)
  Hirokazu, Mizoguchi, et. al.
- Journal Title
  
  Peptides 27
  
  Pages: 2786-2793
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Contribution of spinal μ 1-opioid receptors and dynorphin B to the antinociception induced by Tyr-D-Arg-Phe-Sar2006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Peptides 27
  
  Pages: 2786-2793
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Possible involvement of dynorphin A-(1-17) release via μ_1-opioid receptors in spinal antinociception by endomorphin-22006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  J. Pharmacol. Exp. Ther. 317
  
  Pages: 362-368
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Differential inhibitory effects of μ-opioids on substance P- and capsaicin-induced nociceptive behavior in mice.2006
- Author(s)
  H. Watanabe, D. Nakayama, M. Yuhki, T. Sawai, W. Sakurada, S. Katsuyama, T. Hayashi, C. Watanabe, H. Mizoguchi, T. Fujimura, T. Sakurada, S. Sakurada
- Journal Title
  
  Peptides 27
  
  Pages: 760-768
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Involvement of spinal μ_1-opioid receptors on the Tyr-D-Arg-Phe-sarcosin-induced antinociception2006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur. J. Pharmacol. 540
  
  Pages: 67-72
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Contribution of spinal μ_1-opioid receptors and dynorphin B to the antinociception induced by Tyr-D-Arg-Phe-Sar2006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Peptides 27
  
  Pages: 2786-2793
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Possible involvement of dynorphin A (1-17) release via μ_1-opioid receptors in spinal antinociception by endomorphin-22006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  J.Pharmacol.Exp.Ther. 317
  
  Pages: 362-368
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Possible involvement of dynorphin A(1-17) release via μi opioid receptors in spinal antinociception by endomorphin-22006
- Author(s)
  Hirokazu, Mizoguchi, et. al.
- Journal Title
  
  J. Pharmacol. Exp. Ther 317
  
  Pages: 362-368
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Possible involvement of dynorphin A (1-17) release via μ_1-opioid receptors in spinal antinociception by endomorphin-22006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  J.Pharmacol.Exp.Ther. 317
  
  Pages: 362-368
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Involvement of spinal μ_1-opioid receptors on the Tyr-D-Arg-Phe-sarcosin-induced antinociception2006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur. J. Pharmacol. 540
  
  Pages: 67-72
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Involvement of spinal μ 1-opioid receptors on the Tyr-D-Arg-Phe-sarcosin induced antinociception2006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Eur.J.Pharmacol 540
  
  Pages: 67-72
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Contribution of spinal μ_1-opioid receptors and dynorphin B to the antinociception induced by Tyr-D-Arg-Phe-Sar2006
- Author(s)
  H. Mizoguchi, K. Ito, H. Watanabe, C. Watanabe, S. Katsuyama, T. Fujimura, T. Sakurada, S. Sakurada
- Journal Title
  
  Peptides 27
  
  Pages: 2786-2793
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Involvement of spinal μ_1-opioid receptors on the Tyr-D-Arg-Phe-sarcosin-induced antinociception.2006
- Author(s)
  H. Mizoguchi, D. Nakayama, H. Watanabe, K. Ito, W. Sakurada, T. Sawai, T. Fujimura, T. Sato, T. Sakurada, S. Sakurada
- Journal Title
  
  Eur. J. Pharmacol. 540
  
  Pages: 67-72
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Contribution of spinal μ_1-opioid receptors and dynorphin B to the antinociception induced by Tyr-D-Arg-Phe-Sar2006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Peptides 27
  
  Pages: 2786-2793
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Possible involvement of dynorphin A(1-17) release via μ1-opioid receptors in spinal antinociception by endomorphin-22006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  J.Pharmacol.Exp.Ther 317
  
  Pages: 362-368
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Possible involvement of dynorphin A-(1-17) release via μ_1-opioid receptors in spinal antinociception by endomorphin-2.2006
- Author(s)
  H. Mizoguchi, H. Watanabe, T. Hayashi, W. Sakurada, T. Sawai, T. Fujimura, T. Sakurada, S. Sakurada
- Journal Title
  
  J. Pharmacol. Exp. Ther. 317
  
  Pages: 362-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] Possible involvement of dynorphin A-(1-17) release via μ_1-opioid receptors in spinal antinociception by endomorphin-22006
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  J. Pharmacol. Exp. Ther. 317
  
  Pages: 362-368
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] 冷水強制水泳誘発抗侵害作用の発現における脳内β-endorphinならびにεオピオイド受容体の関与2005
- Author(s)
  溝口広一
- Journal Title
  
  東北薬科大学研究誌 52
  
  Pages: 105-110
- NAID
  40015250165
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Involvement of endogenous β-endorphin and ε-opioid receptors in supraspinal site on the cold water swimming-induced antinociception in mice2005
- Author(s)
  Hirokazu, Mizoguchi, et. al.
- Journal Title
  
  J. Tohoku Pharmaceut. Univ 52
  
  Pages: 105-110
- NAID
  110004814042
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Journal Article] Characterization of intrathecally administered hemokinin-1-induced nociceptive behaviors in mice
- Author(s)
  Chizuko Watanabe, Hirokazu Mizoguchi, Akihiko Yonezawa, Shinobu Sakurada
- Journal Title
  
  Peptide (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18613015
[Journal Article] New therapy for neuropathic pain
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Int. Rev. Neurobiol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603011
[Journal Article] New therapy for neuropathic pain
- Author(s)
  Hirokazu Mizoguchi
- Journal Title
  
  Int. Rev. Neurobiol. (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Journal Article] New therapy for neuropathic pain.
- Author(s)
  H. Mizoguchi, C. Watanabe, A. Yonezawa, S. Sakurada
- Journal Title
  
  Int. Rev. Neurobiol. (in press)
  
  Pages: 0-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 掻痒誘起作用を有する非天然型モルヒナン誘導体の創製2021
- Author(s)
  飯尾啓太、沓村憲樹、南雲康行、斉藤毅、徳田明久、橋本佳応、山本直司、木瀬亮次、井上飛鳥、溝口広一、長瀬博
- Organizer
  新学術領域研究「化学コミュニケーションのフロンティア」第8回公開シンポジウム
- Data Source
  KAKENHI-PROJECT-21K06602
[Presentation] 天然由来成分の抗かゆみ活性2018
- Author(s)
  芦部文一朗、松見繁、丸山徹也、溝口広一、櫻田忍
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 依存性のない新規鎮痛薬の探索2018
- Author(s)
  溝口広一
- Organizer
  第2回仙台痛みフォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 難治性掻痒症治療薬nalfurafineの末梢性抗掻痒作用2017
- Author(s)
  音羽亮、渡辺千寿子、長瀬博、櫻田忍、溝口広一
- Organizer
  第68回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Amidino-TAPAの神経障害性疼痛に対する有効性2017
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、櫻田忍
- Organizer
  第4回包括的緩和医療科学学術研究会・第5回Tokyo疼痛緩和次世代研究会合同研究会
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 炎症性疼痛下における麻薬性鎮痛薬の鎮痛効果ならびに鎮痛耐性形成2017
- Author(s)
  込山麻美、渡辺千寿子、音羽亮、櫻田忍、溝口広一
- Organizer
  平成29年度東北医科薬科大学創薬研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Effectiveness of amidino-TAPA against morphine-resistant neuropathic pain2017
- Author(s)
  Hirokazu Mizoguchi、Chizuko Watanabe、Akira Otowa、Shinobu Sakurada
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 炎症性疼痛制御におけるmethadoneの特異的作用2017
- Author(s)
  込山麻美、渡辺千寿子、音羽亮、櫻田忍、溝口広一
- Organizer
  第68回日本薬理学会北部会
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2017
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、櫻田忍
- Organizer
  平成29年度東北医科薬科大学創薬研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 炎症性疼痛下における各種麻薬性鎮痛薬における鎮痛効果とその耐性形成能2017
- Author(s)
  込山麻美、溝口広一、渡辺千寿子、音羽亮、櫻田忍
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎ブリックホール（長崎県・長崎市）
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Hemokinin-1誘発性疼痛関連行動の発現機構2016
- Author(s)
  渡辺千寿子、溝口広一、音羽亮、櫻田忍
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Nalfurafineの末梢性抗掻痒作用2016
- Author(s)
  音羽亮、溝口広一、渡辺千寿子、長瀬博、櫻田忍
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 炎症性疼痛下における各種麻薬性鎮痛薬の鎮痛効果とその耐性形成能2016
- Author(s)
  込山麻美、溝口広一、渡辺千寿子、音羽亮、櫻田忍
- Organizer
  第67回日本薬理学会北部会
- Place of Presentation
  北海道大学（北海道・札幌市）
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Amidino-TAPAの非依存性に関わるμオピオイド受容体スプライスバリアントの探索2016
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、吉岡麻也、櫻田忍
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Hemokinin-1誘発性疼痛関連行動の発現機構2016
- Author(s)
  渡辺千寿子、溝口広一、音羽亮、櫻田忍
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 炎症性疼痛下における各種麻薬性鎮痛薬の鎮痛効果とその耐性形成能2016
- Author(s)
  込山麻美、溝口広一、渡辺千寿子、音羽亮、櫻田忍
- Organizer
  平成28年度東北医科薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北医科薬科大学（宮城県・仙台市）
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 神経障害性疼痛に対する麻薬性鎮痛薬ならびに新規鎮痛薬の効果2016
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、櫻田忍
- Organizer
  平成28年度東北医科薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北医科薬科大学（宮城県・仙台市）
- Year and Date
  2016-06-18
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Nalfurafineの末梢性抗掻痒作用2016
- Author(s)
  音羽亮、溝口広一、渡辺千寿子、長瀬博、櫻田忍
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Amidino-TAPAの非依存性に関わるμオピオイド受容体スプライスバリアントの探索2016
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、吉岡麻也、櫻田忍
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 難治性掻痒症治療薬nalfurafineの末梢性抗掻痒作用2015
- Author(s)
  音羽亮、小笠原蓉子、新井田隆宏、溝口広一、渡辺千寿子、勝山壮、長瀬博、櫻田忍
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山国際会議場（富山）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] Amidino-TAPAの非依存性に関わるμオピオイド受容体スプライスバリアントの探索2015
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、吉岡麻也、櫻田忍
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  タワーホール船堀（東京）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Amidino-TAPAの非依存性に関わるμオピオイド受容体スプライスバリアントの探索2015
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、吉岡麻也、櫻田忍
- Organizer
  第45回日本神経精神薬理学会・第37回日本生物学的精神医学会合同年会
- Place of Presentation
  タワーホール船堀（東京）
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 難治性掻痒症治療薬nalfurafineの末梢性抗掻痒作用2015
- Author(s)
  音羽亮、小笠原蓉子、新井田隆宏、溝口広一、渡辺千寿子、勝山壮、長瀬博、櫻田忍
- Organizer
  第66回日本薬理学会北部会
- Place of Presentation
  富山国際会議場（富山）
- Year and Date
  2015-09-18
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 多発性硬化症疼痛に対するオピオイド性鎮痛薬の効果2015
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、長瀬博、櫻田忍
- Organizer
  第9回日本緩和医療薬学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K08678
[Presentation] 多発性硬化症疼痛に対するオピオイド性鎮痛薬の効果2015
- Author(s)
  溝口広一、渡辺千寿子、音羽亮、長瀬博、櫻田忍
- Organizer
  第9回日本緩和医療薬学会年会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Antinociceptive effect of narcotic analgesics in neuropathic pain state2014
- Author(s)
  Takahiro Sumi, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Antinociceptive effect of narcotic analgesics in neuropathic pain state2014
- Author(s)
  Takahiro Sumi, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] The antinociceptive effect of opioid analgesics in neuropathic cancer pain2014
- Author(s)
  Ryou Sugawara、Hirokazu Mizoguchi、Chizuko Watanabe、Akihiko Yonezawa、Syu-ichi Kanno、Masaaki Ishikawa、Hiroshi Nagase、Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市（仙台国際センター）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Antipruritic effect of kappa-opioid receptor agonist in mice2014
- Author(s)
  Takahiro Niida, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Antinociceptive effect of narcotic analgesics against mechanical allodynia in inflammatory pain state2014
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Antinociceptive effect of narcotic analgesics against mechanical allodynia in inflammatory pain state2014
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 炎症性疼痛下における麻薬性鎮痛薬の鎮痛作用減弱機構2014
- Author(s)
  溝口広一、渡辺千寿子、櫻田忍
- Organizer
  平成26年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Antinociceptive effect of narcotic analgesics against mechanical allodynia in inflammatory pain state2014
- Author(s)
  Yuta Aoki、Hirokazu Mizoguchi、Chizuko Watanabe、Akihiko Yonezawa、Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市（仙台国際センター）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Antipruritic effect of kappa-opioid receptor agonist in mice2014
- Author(s)
  Takahiro Niida, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] The antinociceptive effect of opioid analgesics in neuropathic cancer pain2014
- Author(s)
  Ryou Sugawara, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Syu-ichi Kanno, Masaaki Ishikawa, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Hemokinin-1誘発性疼痛関連行動の発現機構2014
- Author(s)
  渡辺千寿子、溝口広一、櫻田忍
- Organizer
  平成26年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 炎症性疼痛下における麻薬性鎮痛薬の鎮痛作用減弱機構2014
- Author(s)
  溝口広一、渡辺千寿子、櫻田忍
- Organizer
  平成26年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Antinociceptive effect of narcotic analgesics against mechanical allodynia in inflammatory pain state2014
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Antinociceptive effect of narcotic analgesics in neuropathic pain state2014
- Author(s)
  Takahiro Sumi、Hirokazu Mizoguchi、Chizuko Watanabe、Akihiko Yonezawa、Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台市（仙台国際センター）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Antinociceptive effect of narcotic analgesics in neuropathic pain state2014
- Author(s)
  Takahiro Sumi, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] The antinociceptive effect of opioid analgesics in neuropathic cancer pain2014
- Author(s)
  Ryou Sugawara, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Syu-ichi Kanno, Masaaki Ishikawa, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] The antinociceptive effect of opioid analgesics in neuropathic cancer pain2014
- Author(s)
  Ryou Sugawara, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Syu-ichi Kanno, Masaaki Ishikawa, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 神経障害性疼痛に対するmethadoneの脊髄鎮痛作用2014
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Antipruritic effect of kappa-opioid receptor agonist in mice2014
- Author(s)
  Takahiro Niida, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 神経障害性疼痛に対するmethadoneの脊髄鎮痛作用2014
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 多発性硬化症疼痛に対するオピオイド性鎮痛薬の効果2014
- Author(s)
  溝口広一、渡辺千寿子、長瀬博、櫻田忍
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Hemokinin-1誘発性疼痛関連行動の発現機構2014
- Author(s)
  渡辺千寿子、溝口広一、櫻田忍
- Organizer
  平成26年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Year and Date
  2014-06-14
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 多発性硬化症疼痛に対するオピオイド性鎮痛薬の効果2014
- Author(s)
  溝口広一、渡辺千寿子、長瀬博、櫻田忍
- Organizer
  第126回日本薬理学会近畿部会
- Place of Presentation
  和歌山県JAビル（和歌山）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 神経障害性疼痛における末梢性TRPV1受容体及びNMDA受容体の関与2013
- Author(s)
  遠藤有里子, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] μ受容体作動薬ADAMBの脊髄における抗侵害作用発現機序2013
- Author(s)
  青木祐太, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Phosphorylation of mu opioid receptor reduced morphine analgesia in inflammatory pain state2013
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  International Symposium for Neurosciences 2013
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Involvement of phosphorylation ofμ-opioid receptors on the bilateral reduction of morphine analgesia in inflammatory pain state2013
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2013
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、長瀬博、櫻田司、櫻田忍
- Organizer
  第33回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  神戸大学（神戸）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2013
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、長瀬博、櫻田司、櫻田忍
- Organizer
  第33回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  神戸市（神戸大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Effectiveness of amidino-TAPA against morphine-resistant neuropathic pain2013
- Author(s)
  Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Tsukasa Sakurada, Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Pullman Cairns International (Cairns, Australia)
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Spinal antinociceptive effect of endomorphins in inflammatory pain and neuropathic pain2013
- Author(s)
  Ryo Odagiri, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  International Symposium for Neurosciences 2013
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2013
- Author(s)
  溝口広一, 渡辺千寿子, 米澤章彦, 長瀬博, 櫻田司, 櫻田忍
- Organizer
  第33回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Effectiveness of amidino-TAPA against morphine-resistant neuropathic pain2013
- Author(s)
  Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Tsukasa Sakurada, Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Cairns (Australia)
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] デルモルフィン誘導体TAPAの脊髄鎮痛作用発現機構2013
- Author(s)
  今野崇, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2013
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、長瀬博、櫻田司、櫻田忍
- Organizer
  第33回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  神戸大学（神戸）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Phosphorylation of mu opioid receptor reduced morphine analgesia in inflammatory pain state2013
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Tsukasa Sakurada, Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Pullman Cairns International (Cairns, Australia)
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Distinct physiological role of MOR-1J and MOR-1L on the mouse brain2013
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Year and Date
  2013-03-22
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] Involvement of peripheral TRPV1 receptor in neuropathic pain2013
- Author(s)
  Yuriko Endo, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  International Symposium for Neurosciences 2013
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 神経絞扼性癌性疼痛における麻薬性鎮痛薬の効果2013
- Author(s)
  菅原陵, 溝口広一, 渡辺千寿子, 米澤章彦, 菅野秀一, 石川正明, 櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Phosphorylation of mu opioid receptor reduced morphine analgesia in inflammatory pain state2013
- Author(s)
  Yuta Aoki、Hirokazu Mizoguchi、Chizuko Watanabe、Akihiko Yonezawa、Tsukasa Sakurada、Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Australia, Cairns
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] CB1受容体拮抗薬AM251はERKの活性化を介して疼痛関連行動を起こす2013
- Author(s)
  長岡高史, 勝山壮, 溝口広一, 小松生明, 渡辺千寿子, 米澤章彦, 櫻田司, 櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2013
- Author(s)
  溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 神経障害性疼痛における各種麻薬性鎮痛薬の効果2013
- Author(s)
  角貴祐, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 脊髄疼痛伝達機構に対するμ受容体サブクラスの多様的制御の解析2013
- Author(s)
  高木宏和, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Effectiveness of amidino-TAPA against morphine-resistant neuropathic pain2013
- Author(s)
  Hirokazu Mizoguchi,、Chizuko Watanabe、Akihiko Yonezawa、Tsukasa Sakurada、Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Australia, Cairns
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Phosphorylation of mu opioid receptor reduced morphine analgesia in inflammatory pain state2013
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Tsukasa Sakurada, Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Pullman Cairns International (Cairns, Australia)
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Effectiveness of amidino-TAPA against morphine-resistant neuropathic pain2013
- Author(s)
  Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Tsukasa Sakurada, Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Pullman Cairns International (Cairns, Australia)
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Phosphorylation of mu opioid receptor reduced morphine analgesia in inflammatory pain state2013
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Tsukasa Sakurada, Shinobu Sakurada
- Organizer
  International Narcotic Research Conference
- Place of Presentation
  Cairns (Australia)
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Involvement of altered mu-opioid receptors in spinal cord on the reduced morphine analgesia in inflammatory pain state2012
- Author(s)
  青木祐太, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 炎症性慢性疼痛下におけるmorphineの鎮痛作用減弱機構2012
- Author(s)
  青木祐太, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  平成24年度東北薬科大学創薬センターシンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 難治性疼痛に対する脊髄endomorphinsの効果2012
- Author(s)
  小田桐遼, 青木祐太, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第63回日本薬理学会北部会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 化学的侵害刺激による脊髄内神経伝達物質の遊離量の変化–マウス脊髄マイクロダイアリシス法による検討–2012
- Author(s)
  渡辺千寿子, 溝口広一, 米澤章彦, 櫻田忍
- Organizer
  平成24年度東北薬科大学創薬センターシンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Distinct physiological role of the MOR-1 splice variants in the mouse brain2012
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Society for Neuroscience Neuroscience 2012
- Place of Presentation
  New Orleans (UAS)
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] 多発性硬化症疼痛の実験動物モデルとその特異的治療薬の探索2011
- Author(s)
  溝口広一
- Organizer
  第5回日本緩和医療薬学会年会
- Place of Presentation
  千葉
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] 多発性硬化症疼痛の実験動物モデルとその特異的治療薬の探索2011
- Author(s)
  溝口広一
- Organizer
  第5回日本緩和医療薬学会年会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果2011
- Author(s)
  大槻明日奈, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第5回日本緩和医療薬学会年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛の実験動物モデルとその特異的治療薬の探索2011
- Author(s)
  溝口広一
- Organizer
  第5回日本緩和医療薬学会年会
- Place of Presentation
  千葉
- Year and Date
  2011-09-25
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] Mechanism of reduced morphine analgesia in inflammatory pain state2011
- Author(s)
  Yuta Aoki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  Italian-Japanese International Seminar for Neurosciences
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] Different effectiveness of narcotic analgesics on multiple sclerosis-related chronic pain2011
- Author(s)
  Asuna Otsuki, Hirokazu Mizoguchi, Chizuko Watanabe, Akihiko Yonezawa, Shinobu Sakurada
- Organizer
  Italian-Japanese International Seminar for Neurosciences
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 炎症性慢性疼痛時におけるmorphineの鎮痛作用減弱について2011
- Author(s)
  青木祐太, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第5回日本緩和医療薬学会年会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛の実験動物モデルとその特異的治療薬の探索2011
- Author(s)
  溝口広一
- Organizer
  第5回日本緩和医療薬学会年会
- Place of Presentation
  幕張メッセ(千葉)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] 炎症性慢性疼痛時におけるmorphine鎮痛作用の減弱機構2011
- Author(s)
  青木祐太, 溝口広一, 渡辺千寿子, 米澤章彦, 櫻田忍
- Organizer
  第62回日本薬理学会北部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 難治性疼痛治療薬としての新規ペプチド性鎮痛薬amidino-TAPAの特性2010
- Author(s)
  溝口広一
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] A peptidic analgesic for treatment to morphine-resistant intractable pain2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  MOLECULAR TARGETS FOR NOVEL PAIN THERAPEUTICS From Basic Research to Clinical Translation
- Place of Presentation
  Calabria(Italy)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] Distinct physiological role of spinal mMOR-1 splice variants2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  International Narcotics Research Conference 2010
- Place of Presentation
  Malmo(Sweden)
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] 難治性疼痛治療薬としての新規ペプチド性鎮痛薬amidino-TAPAの特性2010
- Author(s)
  溝口広一
- Organizer
  第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会合同年会
- Place of Presentation
  仙台
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] Distinct physiological role of spinal mMOR-1 splice variants2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  International Narcotics Research Conference
- Place of Presentation
  Malmo (Sweden)
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] A peptidic analgesic for treatment to morphine-resistant intractable pain2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Molecular Targets for Novel Pain Therapeutics : From Basic Research to Clinical Translation
- Place of Presentation
  Calabria (Italy)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] A peptidic analgesic for treatment to morphine-resistant intractable pain2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Molecular Targets for Novel Pain Therapeutics: From Basic Research to Clinical Translation
- Place of Presentation
  Calabria (Italy)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] Distinct physiological role of spinal mMOR-1 splice variants2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  International Narcotics Research Conference
- Place of Presentation
  Malmo(Sweden)
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] Distinct physiological role of spinal mMOR-1 splice variants2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  International Narcotics Research Conference
- Place of Presentation
  Malmo (Sweden)
- Year and Date
  2010-07-12
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] A peptidic analgesic for treatment to morphine-resistant intractable pain2010
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  MOLECULAR TARGETS FOR NOVEL PAIN THERAPEUTICS : From Basic Research to Clinical Translation
- Place of Presentation
  Calabria (Italy)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] 神経障害性疼痛治療薬の開発戦略2009
- Author(s)
  溝口広一
- Organizer
  平成20年度日本薬学会東北支部総会・学術講演会
- Place of Presentation
  仙台
- Year and Date
  2009-07-12
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 難治性疼痛下におけるmorphine鎮痛効力の変化ならびにそのメカニズムの解明2009
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第4回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Antinociceptive profile of novel peptidic analgesics amidino-TAPA.2009
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  First meeting of the Japan Branch of the International Neuropeptide Society
- Place of Presentation
  Sendai
- Year and Date
  2009-08-31
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] Gene-based therapeutic aspects of synthesized opioid peptides against neuropathic pain2009
- Author(s)
  H. Mizoguchi, C. Watanabe, A. Yonezawa, S. Sakurada
- Organizer
  XI WORKSHOP ON APOPTOSIS IN BIOLOGY AND MEDICINE
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Gene-based therapeutic aspect of synthesized opioid peptides against neuropathic pain.2009
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  XI WORKSHOP ON APOPTOSIS IN BIOLOGY AND MEDICINE
- Place of Presentation
  Sendai
- Year and Date
  2009-09-13
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 難治性疼痛下におけるmorphine鎮痛効力の変化ならびにそのメカニズムの解明2009
- Author(s)
  溝口広一
- Organizer
  第4回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-05-29
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] ペプチド性新規難治性疼痛治療薬amidino-TAPAの鎮痛特性2009
- Author(s)
  溝口広一
- Organizer
  第36回薬物活性シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21600013
[Presentation] 神経損傷モデルにおけるヒスタミン誘発疼痛関連行動に及ぼすトランスグルタミナーゼの影響2009
- Author(s)
  円子顕子、小林悠佳、米澤章彦、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第13回日本ヒスタミン学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] エンドモルフィン-2の抗侵害作用における上位中枢μ1オピオイド受容体を介したダイノルフィンA遊離の関与2009
- Author(s)
  澤井敏樹、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第48回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 炎症性疼痛形成時におけるMOR-1スプライスバリアントの発現変化とmorphine鎮痛効力との相関性2009
- Author(s)
  武田久美子、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第18回神経行動薬理若手研究者のつどい
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] ペプチド性新規難治性疼痛治療薬amidino-TAPAの鎮痛特性2009
- Author(s)
  溝口広一、櫻田忍
- Organizer
  第36回薬物活性シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 多発性硬化症疼痛におけるモルヒネの鎮痛効力の変化2009
- Author(s)
  原内珠江、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第48回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 神経障害性疼痛モデルにおけるhistamine誘発性疼痛関連行動の発現機構2008
- Author(s)
  加藤慧、小林悠佳、米澤章彦、渡辺千寿子、溝口広一、櫻田忍
- Organizer
  第3回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 新規鎮痛薬amidino-TAPAの神経障害性疼痛に対する有効性について2008
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第2回日本緩和医療薬学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Antinociceptive property of novel peptidic analgesics, a N-terminal tetrapeptide derivative of dermorphin containing 2', 6'-dimethylphenylalanine (Dmp)2008
- Author(s)
  T. Higashiya, H. Mizoguchi, C. Watanabe, A. Yonezawa, Y. Sasaki, A. Ambo, S. Sakurada
- Organizer
  XI WORKSHOP ON APOPTOSIS IN BIOLOGY AND MEDICINE
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Antinociceptive profile of novel peptidic analgesics amidino-TAPA2008
- Author(s)
  H. Mizoguchi, C. Watanabe, A. Yonezawa, S. Sakurada
- Organizer
  First meeting of the Japan Branch of the International Neuropeptide Society
- Place of Presentation
  Sendai
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 新規鎮痛薬amidino-TAPAの神経障害性疼痛に対する有効性について2008
- Author(s)
  溝口広一
- Organizer
  第2回日本緩和医療薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-10-18
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] Antinociceptive profile of novel peptidic analgesics amidino-TAPA2008
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  First meeting of the Japan Branch of the International Neuropeptide Society
- Place of Presentation
  仙台
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Antinociceptive profile of novel peptidic analgesics amidino-TAPA2008
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  First meeting of the Japan Branch of the International Neuropeptide Society
- Place of Presentation
  仙台
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] [dimethyl-Tyr1]導入endomorphin-1誘導体の薬理特性2008
- Author(s)
  志村幸子、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第59回日本薬理学会北部会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 新規鎮痛薬amidino-TAPAの神経障害性疼痛に対する有効性について2008
- Author(s)
  溝口広一
- Organizer
  第2回日本緩和医療薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-10-18
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 神経障害性疼痛治療薬の開発戦略2008
- Author(s)
  溝口広一
- Organizer
  平成20年度日本薬学会東北支部総会・学術講演会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 難治性疼痛におけるμオピオイド受容体スプライスバリアントの機能的関与2008
- Author(s)
  武田久美子、溝口広一、夏井早苗、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第61回日本薬理学会西南部会
- Place of Presentation
  米子
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Gene-based therapeutic aspect of synthesized opioid peptides against neuropathic pain2008
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  XI WORKSHOP ON APOPTOSIS IN BIOLOGY AND MEDICINE
- Place of Presentation
  仙台
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 依存性の無い難治性疼痛治療薬の開発2008
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第3回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Gene-based therapeutic aspect of synthesized opioid peptides against neuropathic pain2008
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  XI WORKSHOP ON APOPTOSIS IN BIOLOGY AND MEDICINE
- Place of Presentation
  仙台
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 依存性の無い難治性疼痛治療薬の開発2008
- Author(s)
  溝口広一
- Organizer
  第3回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 神経障害性疼痛治療薬の開発戦略2008
- Author(s)
  溝口広一
- Organizer
  平成20年度日本薬学会東北支部総会・学術講演会
- Place of Presentation
  仙台
- Year and Date
  2008-07-12
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 神経因性疼痛に対するamidino-TAPAの抗アロディニア作用とその発現における脊髄μ受容体スプライスバリアントの関与2007
- Author(s)
  溝口広一
- Organizer
  第116回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2007-06-02
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] Amidino-TAPA誘発抗侵害作用の発現におけるμオピオイド受容体スプライスバリアントの関与2007
- Author(s)
  溝口広一
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-15
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] オピオイド性鎮痛薬Morphine, FentanylおよびOxycodoneの抗侵害作用の特性について2007
- Author(s)
  谷内理枝子、米澤章彦、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第46回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 神経障害性疼痛の発現に関わるμオピオイド受容体スプライスバリアントの変化2007
- Author(s)
  夏井早苗、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第46回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Amidino-TAPAのμオピオイド受容体スプライスバリアントに対する選択性とその生理作用への関与について2007
- Author(s)
  夏井早苗、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第2回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Methadoneの上位中枢における抗侵害作用の発現機序について2007
- Author(s)
  吉岡麻也、溝口広一、漆山莉絵、米澤章彦、渡辺千寿子、櫻田忍
- Organizer
  第1回日本緩和医療薬学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] ペプチド性鎮痛薬amidino-TAPAの特性2007
- Author(s)
  溝口広一
- Organizer
  第1回日本緩和医療薬学会年会
- Place of Presentation
  東京
- Year and Date
  2007-10-21
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 依存性の無い難治性疼痛治療薬の開発2007
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第2回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 依存性の無い難治性疼痛薬の開発2007
- Author(s)
  溝口広一
- Organizer
  第2回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] ペプチド性鎮痛薬amidino-TAPAの特性2007
- Author(s)
  溝口広一、櫻田忍
- Organizer
  第1回日本緩和医療薬学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Amidino-TAPA誘発抗侵害作用の発現におけるμオピオイド受容体スプライスバリアントの関与2007
- Author(s)
  溝口広一
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] 神経障害性疼痛モデルマウスの痛覚過敏発現におけるヒスタミンの役割2007
- Author(s)
  小林悠佳、米澤章彦、渡辺千寿子、溝口広一、櫻田忍
- Organizer
  第11回ヒスタミン学会
- Place of Presentation
  富山
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 神経因性疼痛に対するamidino-TAPAの抗アロディニア作用とその発現における脊髄μ受容体スプライスバリアントの関与2007
- Author(s)
  溝口広一、武田哲志、夏井早苗、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第116回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Endomorphinの抗侵害作用における脊髄μ1およびμ2受容体の多様的関与2007
- Author(s)
  高木宏和、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第46回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 神経損傷モデルにおけるヒスタミンの疼痛伝達機構2007
- Author(s)
  小林悠佳、米澤章彦、渡辺千寿子、溝口広一、櫻田忍
- Organizer
  第2回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Amidino-TAPAの脳室内投与における抗侵害作用の特性2007
- Author(s)
  吉岡麻也、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第46回日本薬学会東北支部大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 依存性の無い難治性疼痛治療薬の開発2007
- Author(s)
  溝口広一
- Organizer
  第2回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] ペプチド性鎮痛薬amidhlo-TAPAの特性2007
- Author(s)
  溝口広一
- Organizer
  第1回日本緩和医療薬学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 麻薬性鎮痛薬であるMorphine, FentanylおよびOxycodoneの抗侵害作用の解析について2007
- Author(s)
  谷内理枝子、米澤章彦、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第1回日本緩和医療薬学会年会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 神経因性終痛に対するamidino-TAPAの抗アロディニア作用とその発現における登髄μ受容体スプライスバリアントの関与2007
- Author(s)
  溝口広一
- Organizer
  第116回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] 新規dermorphin N末端テトラペプチド誘導体であるamidino-TAPAの上位中枢における抗侵害作用と動機付け効果2007
- Author(s)
  吉岡麻也、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第28回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-19603011
[Presentation] Antinociceptive profile of novel dermorphin tetrapeptide analog amidino-TAPA2006
- Author(s)
  Hirokazu, Mizoguchi
- Organizer
  Integrated Center of Excellence for Medicinal Chemistry of Neuropeptides "From Endogenous Systems to Medicines"
- Place of Presentation
  Warsaw(Poland)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] Antinociceptive property of new μ-opioid peptide lacking the dependence liability2006
- Author(s)
  Hirokazu, Mizoguchi
- Organizer
  Japanese Narcotics Research Conference 2006
- Place of Presentation
  Wakayama
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] Antinociceptive profile of novel dermorphin tetrapeptide analog amidino-TAPA.2006
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Integrated Center of Excellence for Medicinal Chemistry of Neuropeptides "From Endogenous Systems to Medicines"
- Place of Presentation
  Warsaw (Poland)
- Year and Date
  2006-09-09
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] Lack of the rewarding effect of novel μ-opioid peptide amidino-TAPA2006
- Author(s)
  Hirokazu, Mizoguchi
- Organizer
  1st Symposium for the High Technology Research Program in the Tohoku Pharmaceutical University
- Place of Presentation
  Sendai
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] 新規μオピオイドペプチドamidino-TAPAの精神依存性2006
- Author(s)
  溝口広一
- Organizer
  第1回東北薬科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Year and Date
  2006-05-26
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] 非依存性新規μオピオイドペプチドの抗侵害特性2006
- Author(s)
  溝口広一
- Organizer
  第27回鎮痛薬、オピオイドペプチドシンポジウム
- Place of Presentation
  和歌山
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] 新規μオピオイドペプチドamidino-TAPAの精神依存性2006
- Author(s)
  溝口広一
- Organizer
  第1回東篠科大学ハイテク・リサーチ・シンポジウム
- Place of Presentation
  仙台
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] Involvement of the μ-opioid receptor splice variants on the antinociception induced by amidino-TAPA2006
- Author(s)
  Hirokazu, Mizoguchi
- Organizer
  The 80th Annual Meeting of the Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] 非依存性新規μオピオイドペプチドの抗侵害特性2006
- Author(s)
  溝口広一
- Organizer
  第27回鎮痛薬・オピオイドペプチドシンポジウム
- Place of Presentation
  和歌山
- Year and Date
  2006-09-02
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] Antinociceptive profile of novel dermorphin tetrapeptide analog amidino TAPA2006
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Integrated Center of Excellence for Medicinal Chemistry of Neuropeptides "From Endogenous Systems to Medicines"
- Place of Presentation
  Warsaw(Poland)
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] Involvement of MOR-1K receptor, splicing variant of MOR-1 receptor containing the sequence encoded exon-13 of MOR-1 receptor gene, on the amidino-TAPA-induced antinociception in the mouse spinal cord.2005
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  The 3rd Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  Tokyo
- Year and Date
  2005-12-05
- Data Source
  KAKENHI-PROJECT-17590065
[Presentation] Involvement of MOR-1K receptor, splice variant of MOR-1 receptor containing the sequence encoded exon-13 of MOR-1 receptor gene, on the amidino-TAPA-induced antinociception in the mouse spinal cord2005
- Author(s)
  Hirokazu, Mizoguchi
- Organizer
  The 3rd Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] Involvement of MOR-1K receptor,splicing variant of MOR-1 receptor containing the sequence encoded exon-13 of MOR-1 receptor gene,on the amidino-TAPA-induced antinociception in the mouse spinal cord2005
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  The 3rd Takeda Science Foundation Symposium on PharmaSciences
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590058
[Presentation] 多発性硬化症疼痛の実験モデルの確立とその特異的治療薬の探索
- Author(s)
  溝口広一
- Organizer
  平成24年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Distinct physiological role of the MOR-1 splice variants in the mouse brain
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Society for Neuroscience Neuroscience 2012
- Place of Presentation
  Morial Convention Center (New Orleans, UAS)
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  仙台市（東北薬科大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 脊髄疼痛伝達機構に対するμ受容体サブクラスの多様的制御の解析
- Author(s)
  高木宏和、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台市（東北大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 神経絞扼性癌性疼痛における麻薬性鎮痛薬の効果
- Author(s)
  菅原陵、溝口広一、渡辺千寿子、米澤章彦、菅野秀一、石川正明、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 神経障害性疼痛における末梢性TRPV1受容体及びNMDA受容体の関与
- Author(s)
  遠藤有里子、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台市（東北大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 神経絞扼性癌性疼痛における麻薬性鎮痛薬の効果
- Author(s)
  菅原陵、溝口広一、渡辺千寿子、米澤章彦、菅野秀一、石川正明、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] μ受容体作動薬ADAMBの脊髄における抗侵害作用発現機序
- Author(s)
  青木祐太、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  仙台市（東北薬科大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 脊髄疼痛伝達機構に対するμ受容体サブクラスの多様的制御の解析
- Author(s)
  高木宏和、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] デルモルフィン誘導体TAPAの脊髄鎮痛作用発現機構
- Author(s)
  今野崇、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台市（東北大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 神経障害性疼痛における各種麻薬性鎮痛薬の効果
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] CB1受容体拮抗薬AM251はERKの活性化を介して疼痛関連行動を起こす
- Author(s)
  長岡高史、勝山壮、溝口広一、小松生明、渡辺千寿子、米澤章彦、櫻田司、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 神経障害性疼痛における末梢性TRPV1受容体及びNMDA受容体の関与
- Author(s)
  遠藤有里子、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Distinct physiological role of the MOR-1 splice variants in the mouse brain
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  Society for Neuroscience Neuroscience 2012
- Place of Presentation
  Morial Convention Center (New Orleans, UAS)
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] 多発性硬化症疼痛に対する麻薬性鎮痛薬の効果
- Author(s)
  溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 多発性硬化症疼痛の実験モデルの確立とその特異的治療薬の探索
- Author(s)
  溝口広一
- Organizer
  平成24年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] デルモルフィン誘導体TAPAの脊髄鎮痛作用発現機構
- Author(s)
  今野崇、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 各種難治性疼痛に対する麻薬性鎮痛薬の効果
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  コラッセふくしま（福島）
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Distinct physiological role of MOR-1J and MOR-1L on the mouse brain
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-22600009
[Presentation] 神経障害性疼痛における各種麻薬性鎮痛薬の効果
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 神経障害性疼痛における各種麻薬性鎮痛薬の効果
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台市（東北大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] デルモルフィン誘導体TAPAの脊髄鎮痛作用発現機構
- Author(s)
  今野崇、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] CB1受容体拮抗薬AM251はERKの活性化を介して疼痛関連行動を起こす
- Author(s)
  長岡高史、勝山壮、溝口広一、小松生明、渡辺千寿子、米澤章彦、櫻田司、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] 神経障害性疼痛における末梢性TRPV1受容体及びNMDA受容体の関与
- Author(s)
  遠藤有里子、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] Effects of narcotic analgesics on the multiple sclerosis-related pain
- Author(s)
  Hirokazu Mizoguchi, Takahiro Sumi, Chizuko Watanabe, Asuna Ohtsuki, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] μ受容体作動薬ADAMBの脊髄における抗侵害作用発現機序
- Author(s)
  青木祐太、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Effects of narcotic analgesics on the multiple sclerosis-related pain
- Author(s)
  Hirokazu Mizoguchi, Takahiro Sumi, Chizuko Watanabe, Asuna Ohtsuki, Hiroshi Nagase, Shinobu Sakurada
- Organizer
  第88回日本薬理学会年会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-03-18 – 2015-03-20
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 各種難治性疼痛に対する麻薬性鎮痛薬の効果
- Author(s)
  角貴祐、溝口広一、渡辺千寿子、櫻田忍
- Organizer
  第65回日本薬理学会北部会
- Place of Presentation
  コラッセふくしま（福島）
- Year and Date
  2014-09-26 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] Distinct physiological role of MOR-1J and MOR-1L on the mouse brain
- Author(s)
  Hirokazu Mizoguchi
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] 脊髄疼痛伝達機構に対するμ受容体サブクラスの多様的制御の解析
- Author(s)
  高木宏和、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  東北大学（仙台）
- Data Source
  KAKENHI-PROJECT-24590731
[Presentation] μ受容体作動薬ADAMBの脊髄における抗侵害作用発現機序
- Author(s)
  青木祐太、溝口広一、渡辺千寿子、米澤章彦、櫻田忍
- Organizer
  平成25年度東北薬科大学創薬研究センターシンポジウム
- Place of Presentation
  東北薬科大学（仙台）
- Data Source
  KAKENHI-PROJECT-25460725
[Presentation] CB1受容体拮抗薬AM251はERKの活性化を介して疼痛関連行動を起こす
- Author(s)
  長岡高史、勝山壮、溝口広一、小松生明、渡辺千寿子、米澤章彦、櫻田司、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台市（東北大学）
- Data Source
  KAKENHI-PROJECT-23590718
[Presentation] 神経絞扼性癌性疼痛における麻薬性鎮痛薬の効果
- Author(s)
  菅原陵、溝口広一、渡辺千寿子、米澤章彦、菅野秀一、石川正明、櫻田忍
- Organizer
  第52回日本薬学会東北支部大会
- Place of Presentation
  仙台市（東北大学）
- Data Source
  KAKENHI-PROJECT-23590718

1. SAKURADA Shinobu (30075816)

# of Collaborated Projects: 11 results

# of Collaborated Products: 187 results
2. WATANABE Chizuko (90296020)

# of Collaborated Projects: 6 results

# of Collaborated Products: 128 results
3. Fujii Hideaki (30458757)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. HIRAYAMA Shigeto (40565842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 寺崎哲也 (60155463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 濱村賢吾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 沓村憲樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Mizoguchi Hirokazu 溝口 広一

MIZOGUCHI Hirokazu 溝口 広一

Research Projects

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Co-Researchers

Development of specific therapeutic agents for intractable pruritus without side effectsPrincipal Investigator

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Methadone-used new therapy for morphine-resistant intractable painPrincipal Investigator

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Development of selective agonists for the morphine-insensitive opioid mu receptor splice variants

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Investigation for the histamine-related mechanism of neuropathic pain and development of its therapy

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The mechanism for multiple sclerosis-related pain and its new therapyPrincipal Investigator

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Investigation for the mechanism of neuropathic pain on spinal pain transmission.

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Development of new therapy for neuropathic cancer pain

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Development of the gene therapy against the morphine-resistant intractable pain using endomorphin precursorPrincipal Investigator

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Development of new analgesics and therapy for intractable pain

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Study for reciprocal double effects of nociceptin on spinal pain transmission.

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Identification of novel endogenous mupioid peptide and characterization of its physiological rolesPrincipal Investigator

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Molecular pharmacological study for characterization of new identified iropioid receptor subclass

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[Book] 疾患薬理学2016

Author(s)

Total Pages

Mizoguchi Hirokazu 溝口広一

MIZOGUCHI Hirokazu 溝口広一