ONOUCHI YOSHIHIRO 尾内善広

… Alternative Names

ONOUCHI Yoshihiro 尾内善広

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Researcher Number	30360522
Other IDs
Affiliation (Current)	2025: 千葉大学, 大学院医学研究院, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 千葉大学, 大学院医学研究院, 教授 2013 – 2016: 千葉大学, 医学(系)研究科(研究院), 准教授 2005: RIKEN, Laboratory for Gastrointestinal Diseases, Senior Scientist, 消化器系疾患関連遺伝子研究チーム, 上級研究員 2004: 独立行政法人理化学研究所, 消化器系疾患関連遺伝子研究チーム, 研究員
Review Section/Research Field	Principal Investigator Basic Section 58030:Hygiene and public health-related: excluding laboratory approach / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Pediatrics / Epidemiology and preventive medicine Except Principal Investigator Basic Section 52020:Neurology-related
Keywords	Principal Investigator 遺伝要因 / 川崎病 / 免疫グロブリン / HLA / 個別化医療 / 副反応 / 抗体価 / 新型コロナワクチン / SNP / susceptibility gene … More / Kawasaki disease / 冠動脈病変 / CD40 ligand / 罹患同胞対解析 / 一塩基多型 / 感受性遺伝子 / 頻回罹患例 / 頻回再発例 / 遺伝分子疫学 / 頻回再発 / 巨大冠動脈瘤 … More Except Principal Investigator HLAハプロタイプ / 遺伝子バリアント / 疾患レジストリ / CIDP Less

成人先天性心疾患とがん：合併頻度、固有の発症リスク因子特定と予防へ向けた疫学研究Principal Investigator
- Principal Investigator
  
  尾内善広
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58030:Hygiene and public health-related: excluding laboratory approach
- Research Institution
  Chiba University
疾患レジストリ・バイオバンクを用いたCIDPの遺伝子バイオマーカーの確立
- Principal Investigator
  
  青墳佑弥
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Chiba University
Establishment of models for prediction of antibody responses and risks to side effects after COVID-19 vaccinationPrincipal Investigator
- Principal Investigator
  
  尾内善広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Chiba University
A genetic study of extremely severe Kawasaki disease patientsPrincipal Investigator
- Principal Investigator
  
  ONOUCHI YOSHIHIRO
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Epidemiology and preventive medicine
- Research Institution
  Chiba University
Research for a susceptibility genes of Kawasaki diseasePrincipal Investigator
- Principal Investigator
  
  ONOUCHI Yoshihiro
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  RIKEN

All 2023 2022 2017 2016 2015 2014 2013 2004

All Journal Article Presentation

[Journal Article] Germline variants of IGHV3-53 / V3-66 are determinants of antibody responses to the BNT162b2 mRNA COVID-19 vaccine2022
- Author(s)
  Yoichi Mashimo, Keiko Yamazaki, Takahiro Kageyama, Shigeru Tanaka, Toshibumi Taniguchi, Kazuyuki Matsushita, Hidetoshi Igari, Hideki Hanaoka, Koutaro Yokote, Hiroshi Nakajima, Yoshihiro Onouchi
- Journal Title
  
  J Infect.
  
  Volume: 85 Issue: 6 Pages: 702-769
- DOI
  10.1016/j.jinf.2022.10.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KT0019, KAKENHI-PROJECT-23K24587
[Journal Article] Variations in ORAI1 Gene Associated with Kawasaki Disease2016
- Author(s)
  Onouchi Y, Fukazawa R, Yamamura K, Suzuki H, Kakimoto N, Suenaga T, et al.
- Journal Title
  
  PloS One
  
  Volume: 11 Issue: 1 Pages: e0145486-e0145486
- DOI
  10.1371/journal.pone.0145486
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461624, KAKENHI-PROJECT-25461629, KAKENHI-PROJECT-25293139, KAKENHI-PROJECT-16K10072, KAKENHI-PROJECT-16K10079
[Journal Article] CD40 ligand gene and Kawasaki Disease2004
- Author(s)
  Yoshihiro Onouchi
- Journal Title
  
  European Journal of Human Genetics 12・12
  
  Pages: 1062-1068
- Data Source
  KAKENHI-PROJECT-16591069
[Presentation] Influence of germline variants of IGHV3-53 and IGHV3-66 genes on antibody responses to BNT162b2 mRNA COVID-19 vaccine2023
- Author(s)
  Yoichi Mashimo, Keiko Yamazaki, Takahiro Kageyama, Shigeru Tanaka, Toshibumi Taniguchi, Kazuyuki Matsushita, Hidetoshi Igari, Hideki Hanaoka, Koutaro Yokote, Hiroshi Nakajima, Yoshihiro Onouchi
- Organizer
  Human Genetics Asia 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24587
[Presentation] Influence of germline variants of IGHV3-53 and IGHV3-66 genes on antibody responses to BNT162b2 mRNA COVID-19 vaccine2023
- Author(s)
  Yoichi Mashimo, Keiko Yamazaki, Takahiro Kageyama, Shigeru Tanaka, Toshibumi Taniguchi, Kazuyuki Matsushita, Hidetoshi Igari, Hideki Hanaoka, Koutaro Yokote, Hiroshi Nakajima, Yoshihiro Onouchi
- Organizer
  American Society of Human Genetics 2023 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K24587
[Presentation] Genetic factors of Kawasaki Disease.2017
- Author(s)
  Yoshihiro Onouchi
- Organizer
  The 18th International Vasculitis & ANCA Workshop
- Place of Presentation
  東京大学伊藤国際学術研究センター（東京都）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 川崎病の遺伝的背景解明への取り組み2016
- Author(s)
  尾内善広
- Organizer
  神奈川県川崎病研究会
- Place of Presentation
  新横浜プリンスホテル（神奈川県横浜市）
- Year and Date
  2016-02-27
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 次世代シークエンサーによる川崎病の遺伝要因の解析2016
- Author(s)
  尾内善広
- Organizer
  川崎病セミナーin千葉
- Place of Presentation
  ホテル・ザ・マンハッタン（千葉県千葉市）
- Year and Date
  2016-02-26
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 川崎病の遺伝的背景の解明への取り組み2016
- Author(s)
  尾内善広
- Organizer
  第119回日本小児科学会
- Place of Presentation
  ロイトン札幌（札幌市）
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 全エクソーム解析による川崎病巨大瘤の遺伝的リスクファクターの検索2016
- Author(s)
  尾内善広, 中川英刀, 重水大智, 尾崎浩一, 中村好一, 浅見雄二, 関　満, 小林　徹, 高地雄太, 戸田達史, 佐竹　渉, 羽田　明, 角田達彦, 田中敏博, 伊藤　薫
- Organizer
  第36回日本川崎病学会
- Place of Presentation
  ワークピア横浜（横浜市）
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Genetic factors of Kawasaki disease identified in genome-wide studies2016
- Author(s)
  Yoshihiro Onouchi
- Organizer
  1st International Pediatric Precision Medicine Forum
- Place of Presentation
  上海市（中華人民共和国）
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] A meta-analysis of three Genome-wide association studies identifies a novel susceptibility locus for Kawasaki disease.2016
- Author(s)
  Yoshihiro Onouchi, Jer-Yuarn Wu, Dankyu Yoon, Todd A. Johnson, Akira Hata, Michiaki Kubo, Atsushi Takahashi, Tatsuhiko Tsunoda, Kouichi Ozaki, Toshihiro Tanaka et al.
- Organizer
  The 13th International Congress of Human Genetics
- Place of Presentation
  国立京都国際会館（京都市）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 川崎病の遺伝的背景の解明への取り組み2016
- Author(s)
  尾内善広
- Organizer
  日本小児科学会
- Place of Presentation
  ロイトン札幌（北海道札幌市）
- Year and Date
  2016-05-13
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Genetic Studies of Kawasaki Disease in Japan2015
- Author(s)
  Yoshihiro Onouchi
- Organizer
  11th International Kawasaki Disease Symposium
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-02-03
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Susceptibility genes for Kawasaki Disease identified by genome-wide studies in Japan2015
- Author(s)
  Yoshihiro Onouchi
- Organizer
  11th Congress of Asian Society for Pediatric Research
- Place of Presentation
  大阪国際会議場（大阪市、北区）
- Year and Date
  2015-04-17
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Genetics of Kawasaki disease2014
- Author(s)
  尾内善広
- Organizer
  日本川崎病学会
- Place of Presentation
  学術総合センター（東京都、千代田区）
- Year and Date
  2014-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 川崎病の遺伝背景解明でめざすもの　-成果と課題-2014
- Author(s)
  尾内善広
- Organizer
  第15回北海道川崎病研究会
- Place of Presentation
  札幌アスペンホテル（札幌市、北区）
- Year and Date
  2014-09-20
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Pathophysiological Basis for Genetic Research in Kawasaki Disease2014
- Author(s)
  Yoshihiro Onouchi
- Organizer
  American College of Cardiology 63rd Annual Scientific Session
- Place of Presentation
  Washington DC, USA
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] GWAS and Kawasaki Disease2014
- Author(s)
  Yoshihiro Onouchi
- Organizer
  The Pediatric Academic Societies and The Asian Socisety of Pediatric Research Joint Meeting 2014
- Place of Presentation
  Vancouver, Canada
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Genome-wide Association Studies and Kawasaki Disease2014
- Author(s)
  Yoshihiro Onouchi
- Organizer
  The Pediatric Acaddemic Societies and The Asian Society of Pediatric Research Joint Meeting 2014
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-05-05
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] Genetic Factors of Kawasaki Disease2013
- Author(s)
  Yoshihiro Onouchi
- Organizer
  2nd Oriental Congress of Pediatrics
- Place of Presentation
  Shanghai, China
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 多因子遺伝性疾患研究の現状～川崎病を例に～2013
- Author(s)
  尾内善広
- Organizer
  第58回日本未熟児新生児学会CLD遺伝セミナー
- Place of Presentation
  金沢市
- Invited
- Data Source
  KAKENHI-PROJECT-25293139
[Presentation] 川崎病の遺伝要因解明の現状2013
- Author(s)
  尾内善広
- Organizer
  日本川崎病学会
- Place of Presentation
  富山市
- Invited
- Data Source
  KAKENHI-PROJECT-25293139

1. NAKAMURA Yosikazu (50217915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. OZAKI Kouichi (50373288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. SAJI Tsutomu (50120275)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KISHI Fumio (40153077)

# of Collaborated Projects: 1 results

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5. OUCHI Kazunobu (80351899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 青墳佑弥 (40919479)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 澤井摂 (10400962)

# of Collaborated Projects: 1 results

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8. 三澤園子 (30375753)

# of Collaborated Projects: 1 results

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9. 桑原聡 (70282481)

# of Collaborated Projects: 1 results

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10. 山崎慶子 (50415329)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. NAKAGAWA Hidewaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. SHIGEMIZU Daichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. RYUJI Fukazawa

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# of Collaborated Products: 1 results
14. 松下一之

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# of Collaborated Products: 1 results

ONOUCHI YOSHIHIRO 尾内 善広

ONOUCHI Yoshihiro 尾内 善広

Research Projects

Research Products

Co-Researchers

成人先天性心疾患とがん：合併頻度、固有の発症リスク因子特定と予防へ向けた疫学研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

疾患レジストリ・バイオバンクを用いたCIDPの遺伝子バイオマーカーの確立

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of models for prediction of antibody responses and risks to side effects after COVID-19 vaccinationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A genetic study of extremely severe Kawasaki disease patientsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Research for a susceptibility genes of Kawasaki diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Germline variants of IGHV3-53 / V3-66 are determinants of antibody responses to the BNT162b2 mRNA COVID-19 vaccine2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variations in ORAI1 Gene Associated with Kawasaki Disease2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD40 ligand gene and Kawasaki Disease2004

Author(s)

Journal Title

Data Source

[Presentation] Influence of germline variants of IGHV3-53 and IGHV3-66 genes on antibody responses to BNT162b2 mRNA COVID-19 vaccine2023

Author(s)

Organizer

Data Source

[Presentation] Influence of germline variants of IGHV3-53 and IGHV3-66 genes on antibody responses to BNT162b2 mRNA COVID-19 vaccine2023

Author(s)

Organizer

Data Source

[Presentation] Genetic factors of Kawasaki Disease.2017

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 川崎病の遺伝的背景解明への取り組み2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 次世代シークエンサーによる川崎病の遺伝要因の解析2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 川崎病の遺伝的背景の解明への取り組み2016

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 全エクソーム解析による川崎病巨大瘤の遺伝的リスクファクターの検索2016

ONOUCHI YOSHIHIRO 尾内善広

ONOUCHI Yoshihiro 尾内善広

[Presentation] 川崎病の遺伝背景解明でめざすもの　-成果と課題-2014