Hotta Kikuko 堀田紀久子

… Alternative Names

堀田紀久子ホッタキクコ

HOTTA Kikuko 堀田紀久子

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Researcher Number	30360639
Other IDs
Affiliation (Current)	2025: 大阪大谷大学, 薬学部, 教授
Affiliation (based on the past Project Information) *help	2023: 大阪大谷大学, 薬学部, 教授 2019 – 2021: 大阪大谷大学, 薬学部, 教授 2016 – 2018: 大阪大学, 医学部附属病院, 特任講師(常勤) 2015: 大阪大学, 医学部附属病院, 講師 2013 – 2014: 京都大学, 医学(系)研究科(研究院), 助教 … More 2012: 京都大学, 医学(系)研究科(研究院), 特定助教 2010 – 2011: 京都大学, 医学研究科, 助教 2009: The Institute of Physical and Chemical Research, 内分泌・代謝疾患研究チーム, 上級研究員 2004 – 2007: 独立行政法人理化学研究所, 肥満関連遺伝子研究チーム, チームリーダー Less
Review Section/Research Field	Principal Investigator Metabolomics / Basic Section 54040:Metabolism and endocrinology-related / Endocrinology Except Principal Investigator Gastroenterology / Metabolomics / Tumor diagnosis
Keywords	Principal Investigator 非アルコール性脂肪肝疾患 / メチル化 / メタボリックシンドローム / 内臓脂肪 / MTMR9 / 肥満 / DNAメチル化 / Obesity / Gap junction / RNAシークエンス … More / エピゲノム / 内臓脂肪蓄積 / 視床下部 / 肝癌 / 肝硬変 / ネットワーク / ゲノム / 遺伝子ネットワーク解析 / 次世代シークエンス / エクソンシークエンス / メチル化解析 / RNAシークエンシング / Co-methylation解析 / ネットワーク解析 / DMR / 遺伝子共発現ネットワーク解析 / Metabolic syndrome / Hypothalamus / レプチン / Connexin 43 / Differentiation / Adipocyte / 糖尿病 / connexin43 / convexin43 / 分化 / 脂肪細胞 / ターゲット・リシークエンス / PNPLA3 / メチル化DNA / 遺伝子多型 / 次世代シークエンサー / SEC16B / セクレトグラニン3 / セクレトグラニン2 / 非アルコール性脂肪肝炎 / 肥満症 / 皮下脂肪 / 肥満関連遺伝子 / FTO / PNPLA1 / MKKS / NT5C2 / CYP17A1 / SH2B1 / SCG3 … More Except Principal Investigator 次世代シークエンス / エピゲノム / 非アルコール性脂肪肝疾患 / 次世代シーケンサー / ゲノム / 次世代シーケンス / メチル化 / 2型糖尿病 / 肥満 / アカゲザル / メタボリックシンドローム / 異所性脂肪蓄積 / PARVB / SAMM50 / PNPLA3 / 次世代シークエンサー / 非アルコール性脂肪肝炎 / ゲノムワイド相関解析 Less

肝疾患の発症・進行に関連するエピゲノムネットワークの調節因子の同定Principal Investigator
- Principal Investigator
  
  堀田紀久子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Osaka Ohtani University
Genomic and epigenomic analysis of non-alcoholic fatty liver diseasePrincipal Investigator
- Principal Investigator
  
  Hotta Kikuko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Osaka Ohtani University
Elucidation of pathophysiology and development of diagnosis method of non-alcoholic fatty liver disease by genomic and epigenomic analysisPrincipal Investigator
- Principal Investigator
  
  Hotta Kikuko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
非アルコール性脂肪肝障害の発症・進行に関連する遺伝素因と環境因子の解析
- Principal Investigator
  
  北本卓也
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
The search and prospective follow-up study of genetic predisposition and environmental factors of ectopic fat accumulationPrincipal Investigator
- Principal Investigator
  
  Hotta Kikuko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Osaka University
  Kyoto University
Analysis of the mechanism for liver cancer developing from non-alcoholic steatohepatitis by next-generation sequencing
- Principal Investigator
  
  KITAMOTO Takuya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnosis
- Research Institution
  Kyoto University
Genomic analysis of caloric restricted, obese and type 2 diabetic rhesus monkeys by next-generation sequencing
- Principal Investigator
  
  KITAMOTO Aya
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Kyoto University
A functional analysis of novel obesity-related genes and a search for obesity-related genesPrincipal Investigator
- Principal Investigator
  
  HOTTA Kikuko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Kyoto University
  The Institute of Physical and Chemical Research
Functional analysis of a novel metabolic syndrome related genePrincipal Investigator
- Principal Investigator
  
  HOTTA Kikuko
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  The Institute of Physical and Chemical Research
Functional analysis of an obesity and diabetes mellitus related novel genePrincipal Investigator
- Principal Investigator
  
  HOTTA Kikuko
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  RIKEN

[Journal Article] Identification of differentially methylated regions associated with both liver fibrosis and hepatocellular carcinoma2024
- Author(s)
  Kurokawa Suguru、Kobori Takuro、Yoneda Masato、Ogawa Yuji、Honda Yasushi、Kessoku Takaomi、Imajo Kento、Saito Satoru、Nakajima Atsushi、Hotta Kikuko
- Journal Title
  
  BMC Gastroenterology
  
  Volume: 24 Issue: 1 Pages: 57-66
- DOI
  10.1186/s12876-024-03149-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K11715, KAKENHI-PROJECT-23K08019
[Journal Article] Association of protein tyrosine phosphatase 1B gene polymorphism with the effects of weight reduction therapy on bodyweight and glycolipid profiles in obese patients2021
- Author(s)
  Yamakage Hajime、Konishi Yousuke、Muranaka Kazuya、Hotta Kikuko、Miyamoto Yoshihiro、Morisaki Hiroko、Morisaki Takayuki、Satoh‐Asahara Noriko
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: - Issue: 8 Pages: 1462-1470
- DOI
  10.1111/jdi.13492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08979
[Journal Article] Novel mutation identified in Leber congenital amaurosis - a case report2020
- Author(s)
  Sato Shigeru、Morimoto Takeshi、Tanaka Sayaka、Hotta Kikuko、Fujikado Takashi、Tsujikawa Motokazu、Nishida Kohji
- Journal Title
  
  BMC Ophthalmology
  
  Volume: 20 Issue: 1 Pages: 313-313
- DOI
  10.1186/s12886-020-01577-9
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08979, KAKENHI-PROJECT-19K09992, KAKENHI-PROJECT-18K19616, KAKENHI-PROJECT-18H04116, KAKENHI-PROJECT-19H01063, KAKENHI-PROJECT-17K11448
[Journal Article] Eleven-year follow-up of a Japanese retinitis pigmentosa patient with an HK1 gene mutation.2019
- Author(s)
  Sato S, Morimoto T, Hotta K, Fujikado T, Nishida K
- Journal Title
  
  Ophthalmic Genet.
  
  Volume: 40 Issue: 5 Pages: 466-469
- DOI
  10.1080/13816810.2019.1678179
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08979, KAKENHI-PROJECT-19K09992, KAKENHI-PROJECT-18K19616, KAKENHI-PROJECT-16H05487, KAKENHI-PROJECT-19H01063
[Journal Article] Identification of the genomic region under epigenetic regulation during non-alcoholic fatty liver disease progression.2018
- Author(s)
  Hotta K, Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Kessoku T, Yoneda M, Imajo K, Tomeno W, Saito S, Nakajima A
- Journal Title
  
  Hepatology Research
  
  Volume: 48 Issue: 3
- DOI
  10.1111/hepr.12992
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09781
[Journal Article] Identification of differentially methylated region (DMR) networks associated with progression of nonalcoholic fatty liver disease.2018
- Author(s)
  Hotta K, Kitamoto A, Kitamoto T, Ogawa Y, Honda Y, Kessoku T, Yoneda M, Imajo K, Tomeno W, Saito S, Nakajima A
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 13567-13567
- DOI
  10.1038/s41598-018-31886-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06179, KAKENHI-PROJECT-16K09781
[Journal Article] Identification of core gene networks and hub genes associated with progression of nonalcoholic fatty liver disease by RNA sequencing2017
- Author(s)
  Hotta K, Kikuchi M, Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Kessoku T, Kobayashi K, Yoneda, M, Imajo K, Tomeno W, Nakaya A, Suzuki Y, Saito S, and Nakajima A
- Journal Title
  
  Hepatology Research
  
  Volume: 印刷中 Issue: 13 Pages: 1445-1448
- DOI
  10.1111/hepr.12877
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-16K09781
[Journal Article] Influence of the rs738409 polymorphism in patatin-like phospholipase 3 on the treatment efficacy of non-alcoholic fatty liver disease with type 2 diabetes mellitus.2016
- Author(s)
  Kan H, Hyogo H, Ochi H, Hotta K, Fukuhara T, Kobayashi T, Naeshiro N, Honda Y, Kawaoka T, Tsuge M, Hiramatsu A, Imamura M, Kawakami Y, Aikata H, Chayama K
- Journal Title
  
  Hepatol Res
  
  Volume: 46 Issue: 3 Pages: 146-153
- DOI
  10.1111/hepr.12552
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343
[Journal Article] <i>CDH13</i> Polymorphisms are Associated with Adiponectin Levels and Metabolic Syndrome Traits Independently of Visceral Fat Mass2016
- Author(s)
  Kitamoto A, Kitamoto T, Nakamura T, Matsuo T, Nakata Y, Hyogo H, Ochi H, Kamohara S, Miyatake N, Kotani K, Mineo I, Wada J, Ogawa Y, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Masuzaki H, Ueno T, Chayama K, Hamaguchi K, Yamada K, Hanafusa T, Oikawa S, Sakata T, Tanaka K, Matsuzawa Y, Hotta K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 23 Issue: 3 Pages: 309-319
- DOI
  10.5551/jat.31567
- NAID
  130005131888
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461343
[Journal Article] The characteristics of non-obese NAFLD: Effect of genetic and environmental factors.2016
- Author(s)
  Honda Y, Yoneda M, Kessoku T, Ogawa Y, Tomeno W, Imajo K, Mawatari H, Fujita K, Hyogo H, Ueno T, Chayama K, Saito S, Nakajima A, Hotta K
- Journal Title
  
  Hepatol Res
  
  Volume: - Issue: 10 Pages: 636-636
- DOI
  10.1111/hepr.12648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461343, KAKENHI-PROJECT-26860516, KAKENHI-PROJECT-15K19340, KAKENHI-PROJECT-16K09781, KAKENHI-PROJECT-16K19357
[Journal Article] Targeted-bisulfite sequence analysis of the methylation of CpG islands in genes encoding PNPLA3, SAMM50, and PARVB of patients with nonalcoholic fatty liver disease.2015
- Author(s)
  Kitamoto T, Kitamoto A, Ogawa Y, Honda Y, Imajo K, Saito S, Yoneda M, Nakamura T, Nakajima A, Hotta K.
- Journal Title
  
  J Hepatol
  
  Volume: 印刷中 Issue: 2 Pages: 494-502
- DOI
  10.1016/j.jhep.2015.02.049
- NAID
  120005690144
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343, KAKENHI-PROJECT-26460999, KAKENHI-PROJECT-26870290
[Journal Article] <i>ADIPOQ</i> polymorphisms are associated with insulin resistance in Japanese women2015
- Author(s)
  KitamotoA, KitamotoT, SoR, MatsuoT, NakataY, HyogoH, OchiH, NakamuraT, KamoharaS, MiyatakeN, KotaniK, MineoI, WadaJ, OgawaY, YonedaM, NakajimaA, FunahashiT, MiyazakiS, TokunagaK, MasuzakiH, UenoT, ChayamaK, HamaguchiK, YamadaK, HanafusaT, OikawaS, SakataT, TanakaK, MatsuzawaY, HottaK.
- Journal Title
  
  Endocr J
  
  Volume: 62 Issue: 6 Pages: 513-521
- DOI
  10.1507/endocrj.EJ14-0574
- NAID
  130005085774
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460999, KAKENHI-PROJECT-26870290, KAKENHI-PROJECT-14F04009, KAKENHI-PROJECT-25461343
[Journal Article] Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease2014
- Author(s)
  Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Nakao K, Sekine A, Chayama K, Nakajima A, Hotta K
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 6 Issue: 5 Pages: 241-6
- DOI
  10.1038/jhg.2014.17
- NAID
  120005477223
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-25870378, KAKENHI-PROJECT-26670383
[Journal Article] Association of polymorphisms in GCKR and TRIB1 with nonalcoholic fatty liver disease and metabolic syndrome traits2014
- Author(s)
  Kitamoto A, Kitamoto T, Nakamura T, Ogawa Y, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Nakao K, Sekine A, Chayama K, Nakajima A, Hotta K
- Journal Title
  
  Endocrine Journal
  
  Volume: 8
- NAID
  130004677938
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461343
[Journal Article] Replication Study of 15 Recently Published Loci for Body Fat Distribution in the Japanese Population2013
- Author(s)
  Hotta K
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 20 Issue: 4 Pages: 336-350
- DOI
  10.5551/jat.14589
- NAID
  130004444671
- ISSN
  1340-3478, 1880-3873
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701082, KAKENHI-PROJECT-23791027
[Journal Article] Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan.2013
- Author(s)
  Kitamoto T
- Journal Title
  
  Human Genetics
  
  Volume: 3 Issue: 7 Pages: 1-10
- DOI
  10.1007/s00439-013-1294-3
- NAID
  120005474457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701082, KAKENHI-PROJECT-23791027, KAKENHI-PROJECT-25670369, KAKENHI-PROJECT-25870378
[Journal Article] Genome-wide scan revealed that polymorphisms in the PNPLA3, SAMM50, and PARVB genes are associated with development and progression of nonalcoholic fatty liver disease in Japan2013
- Author(s)
  Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Nakamura T, Teranishi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A, Hotta K.
- Journal Title
  
  Hum Genet
  
  Volume: (印刷中)
- NAID
  120005474457
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23701082
[Journal Article] Genetic variations in the CYP17A1 and NT5C2 genes are associated with a reduction in visceral and subcutaneous fat areas in Japanese women2012
- Author(s)
  Hotta K, et al (last)
- Journal Title
  
  J Hum Genet
  
  Volume: 57 Issue: 1 Pages: 46-51
- DOI
  10.1038/jhg.2011.127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176, KAKENHI-PROJECT-21591186, KAKENHI-PROJECT-22700689, KAKENHI-PROJECT-23701082, KAKENHI-PROJECT-23791027, KAKENHI-PROJECT-24591338
[Journal Article] Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography2012
- Author(s)
  Hotta K, et al (last)
- Journal Title
  
  J Hum Genet
  
  Volume: (In press) Issue: 5 Pages: 305-310
- DOI
  10.1038/jhg.2012.21
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176, KAKENHI-PROJECT-21591186, KAKENHI-PROJECT-23650429, KAKENHI-PROJECT-23701082, KAKENHI-PROJECT-23791027, KAKENHI-PROJECT-24591338
[Journal Article] Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population2011
- Author(s)
  Hotta K, et al (last)
- Journal Title
  
  J Hum Genet
  
  Volume: 56 Issue: 9 Pages: 716-719
- DOI
  10.1038/jhg.2011.74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176, KAKENHI-PROJECT-21590864, KAKENHI-PROJECT-21591186, KAKENHI-PROJECT-22700689, KAKENHI-PROJECT-23701082, KAKENHI-PROJECT-23791027
[Journal Article] Computed tomography analysis of the association between the SH2B1 rs7498665 single-nucleotide polymorphism and visceral fat area2011
- Author(s)
  Hotta K, et al (last)
- Journal Title
  
  J Hum Genet
  
  Volume: 56 Issue: 10 Pages: 716-719
- DOI
  10.1038/jhg.2011.86
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390176, KAKENHI-PROJECT-21591186, KAKENHI-PROJECT-22700689, KAKENHI-PROJECT-23701082, KAKENHI-PROJECT-23791027
[Journal Article] Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.2010
- Author(s)
  Hotta K, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A.
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 11 Pages: 172-181
- NAID
  120002949731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease2010
- Author(s)
  Hotta K, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A
- Journal Title
  
  BMC Med Genet
  
  Volume: 11(1) Issue: 1 Pages: 172-172
- DOI
  10.1186/1471-2350-11-172
- NAID
  120002949731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186, KAKENHI-PROJECT-22790660
[Journal Article] Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R and their effect on visceral fat area in the Japanese population2010
- Author(s)
  Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Masuzaki H, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa
- Journal Title
  
  J Hum Genet
  
  Volume: 55(11) Issue: 11 Pages: 738-742
- DOI
  10.1038/jhg.2010.99
- NAID
  10030737572
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186, KAKENHI-PROJECT-22700689
[Journal Article] Polymorphisms in NRXN3, TFAP2B, MSRA, LYPLAL1, FTO and MC4R I and their effect on visceral fat area in the Japanese population.2010
- Author(s)
  Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Masuzaki H, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K, Sakata T, Matsuzawa Y, Nakamura Y, Kamatani N.
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 55 Pages: 738-742
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Screening of 336 single-nucleotide polymorphisms in 85 obesity-related genes revealed McKusick-Kaufman syndrome gene variants are associated with metabolic syndrome2009
- Author(s)
  Hotta K, Nakamura T, Takasaki J, Takahashi H, Takahashi A, Nakata Y, Kamohara S, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yo
- Journal Title
  
  J Hum Genet
  
  Volume: 54(4) Issue: 4 Pages: 230-235
- DOI
  10.1038/jhg.2009.16
- NAID
  10030730053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Secretogranin II binds to secretogranin III and forms secretory granules withorexin, neuropeptide Y, and POMC2009
- Author(s)
  Hotta K, Hosaka M, Tanabe A Takeuchi T
- Journal Title
  
  J Endocrinol
  
  Volume: 202(1) Issue: 1 Pages: 111-121
- DOI
  10.1677/joe-08-0531
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Association between obesity and polymorphisms inSEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population2009
- Author(s)
  Hotta K, Nakamura M, Nakamura T, Matsuo T, Nakata Y, Kamohara S, Miyatake N, Kotani K, Komatsu R, Itoh N, Mineo I, Wada J, Masuzaki H, Yoneda M, Nakajima A, Funahashi T, Miyazaki S, Tokunaga K, Kawamoto M, Ueno T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa
- Journal Title
  
  J Hum Genet
  
  Volume: 54(12) Issue: 12 Pages: 727-731
- DOI
  10.1038/jhg.2009.106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Influence of inducible nitric oxide synthase polymorphisms in Japanese patients with on-alcoholic fatty liver disease2009
- Author(s)
  Yoneda M, Hotta K, Nozaki Y, Endo H, Tomeno W, Watanabe S, Hosono K, Mawatari H, Iida H, Fujita K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M, Kubota K, Shimamura T, Saito S, Maeyama S, Wada K Nakajima A
- Journal Title
  
  Hepatol Res
  
  Volume: 39(10) Issue: 10 Pages: 963-971
- DOI
  10.1111/j.1872-034x.2009.00539.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population2009
- Author(s)
  Kikuko Hotta
- Journal Title
  
  Journal of Human Genetics 54
  
  Pages: 727-731
- NAID
  10030732862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Association between angiotensin II type 1receptor polymorphisms and the occurrence of nonalcoholic fatty liver disease2009
- Author(s)
  Yoneda M, Hotta K, Nozaki Y, Endo H, Uchiyama T, Mawatari H, Iida H, Kato S, Fujita K, Takahashi H, Kirikoshi H, Kobayashi N, Inamori M, Abe Y, Kubota K, Saito S, Maeyama S, Wada K Nakajima A
- Journal Title
  
  Liver Int
  
  Volume: 29(7) Issue: 7 Pages: 1078-1085
- DOI
  10.1111/j.1478-3231.2009.01988.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591186
[Journal Article] Association of single-nucleotide polymorphisms in MTMR9 gene with obesity2007
- Author(s)
  Yanagiya, T., Tanabe, A., Iida, A., Saito, S., Sekine, A., Takahashi, A., Tsunoda, T., Kamohara, S., Nakata, Y., Kotani, K., Komatsu, R., Itoh, N., Mineo, I., Wada, J., Masuzaki, H., Yoneda, M., Nakajima, A., Miyazaki, S., Tokunaga, K., Kawamoto, M., Funahashi, T.,Hamaguchi, K.,Tanaka, K.,Yamada, K., Hanafusa, T., Oikawa, S., Yoshimatsu, H., Nakao, K., Sakata, T., Matsuzawa, Y., Kamatani, N., Nakamuara, Y., Hotta, K
- Journal Title
  
  Hum. Mol. Genet. 16
  
  Pages: 3017-3026
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591012
[Journal Article] Association of single-nucleotide polymorphisms in MTMR9 gene with obesity2007
- Author(s)
  Yanagiya, T., Tanabe, A., Iida, A., Saito, S., Sekine, A., Takahashi, A., Tsunoda, T., Kamohara, S., Nakata, Y., Kotani, K., Komatsu, R., Itoh, N., Mineo, I., Wada, J., Masuzaki, H., Yoneda, M., Nakajima, A., Miyazaki, S., Tokunaga, K., Kawamoto, M., Funahashi, T., Hamaguchi, K., Tanaka, K., Yamada, K., Hanafusa, T., Oikawa, S., Yoshimatsu, H., Nakao, K., Sakata, T., Matsuzawa, Y., Kamatani, N., Nakamura, Y., Hotta, K
- Journal Title
  
  Hum.Mol.Genet. 16
  
  Pages: 3017-3026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18591012
[Patent] 肥満の検査方法及び肥満の予防又は治療薬のスクリーニング方法2007
- Inventor(s)
  堀田紀久子, 柳谷隆宏
- Industrial Property Rights Holder
  独立行政法人理化学研究所
- Industrial Property Number
  2007-163399
- Filing Date
  2007-06-21
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591012
[Presentation] 非アルコール性脂肪肝疾患、C型肝炎、肝臓癌でのメチル化レベルの比較2022
- Author(s)
  堀田紀久子
- Organizer
  第42回日本肥満学会
- Data Source
  KAKENHI-PROJECT-19K08979
[Presentation] PTP1B遺伝子多型は日本人のBMI及び減量治療抵抗性に関連する2021
- Author(s)
  浅原哲子、山蔭一、小西陽介、村中和哉、堀田紀久子、宮本恵宏、森崎裕子、森崎隆幸
- Organizer
  日本肥満学会
- Data Source
  KAKENHI-PROJECT-19K08979
[Presentation] 非アルコール性脂肪肝疾患と肝臓癌でのメチル化解析2021
- Author(s)
  堀田紀久子
- Organizer
  日本肥満学会
- Data Source
  KAKENHI-PROJECT-19K08979
[Presentation] CDH13遺伝子の多型は血中アディポネクチン、内臓脂肪と独立してメタボリックシンドロームに関連している2019
- Author(s)
  北本綾、北本卓也、内田千晴、堀田紀久子
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K08979
[Presentation] 非アルコール性脂肪肝疾患におけるdifferentially methylated regions（DMRs）のネットワーク解析2019
- Author(s)
  堀田紀久子, 北本綾, 北本卓也, 小川祐二, 本多靖, 結束貴臣, 米田正人, 今城健人, 留野渉, 斉藤聡, 中島淳
- Organizer
  第40回日本肥満学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08979
[Presentation] 非アルコール性脂肪肝疾患のゲノムワイドメチル化解析2018
- Author(s)
  堀田紀久子、北本綾、北本卓也、小川祐二、本多靖、結束貴臣、米田正人、今城健人、留野渉、斉藤聡、中島淳
- Organizer
  日本人類遺伝学会第63回大会
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] 非アルコール性脂肪肝疾患のゲノムワイドメチル化解析2018
- Author(s)
  堀田紀久子、北本綾、北本卓也、小川祐二、本多靖、結束貴臣、米田正人、今城健人、留野渉、斉藤聡、中島淳
- Organizer
  第39回日本肥満学会
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] 非アルコール性脂肪肝疾患のゲノムワイドメチル化解析2018
- Author(s)
  堀田紀久子、北本卓也、北本綾、小川祐二、本多靖、結束貴臣、米田正人、今城健人、中島淳
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] 非アルコール性脂肪肝疾患の肝生検組織のRNAシークエンスと遺伝子共発現ネットワークの探索2017
- Author(s)
  堀田紀久子，北本卓也，北本綾，小川祐二，本多靖，米田正人，今城健人，鈴木穣，中島淳
- Organizer
  第60 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] 非アルコール性脂肪肝疾患の肝生検組織のRNAシークエンスによる遺伝子共発現ネットワーク解析2017
- Author(s)
  堀田紀久子、北本卓也、北本綾、小川祐二、本多靖、米田正人、今城健人、鈴木穣、中島淳
- Organizer
  第38回日本肥満学会
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] 非アルコール性脂肪肝疾患の肝生検組織のRNAシークエンスと遺伝子共発現ネットワーク解析2017
- Author(s)
  堀田紀久子、北本卓也、北本綾、小川祐二、本多靖、米田正人、今城健人、鈴木穣、中島淳
- Organizer
  日本人類遺伝学会　第62回大会
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] CDH13とADIPOQ多型，内臓脂肪，アディポネクチン，メタボリックシンドロームとの関連2016
- Author(s)
  堀田紀久子，小谷一晃，嶺尾郁夫，和田淳，宮崎滋，徳永勝人，益崎裕章，濱口和之，山田研太郎，花房俊昭，及川眞一，坂田利家，船橋徹，松澤佑次
- Organizer
  第59 回日本糖尿病学会年次学術集会会長
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] Targeted-bisulfite sequence analysis of the methylation of CpG islands in the PNPLA3, SAMM50, and PARVB of patients with nonalcoholic fatty liver disease: relationship to their mRNA expression and rs738409 genotype2016
- Author(s)
  Hotta K, Ogawa Y, Honda Y, Imajo K, Sito S, Yoneda M, Nakajima A
- Organizer
  The 13th International Congress of Human Genetics
- Place of Presentation
  京都国際会館（京都府京都市）
- Year and Date
  2016-04-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] CDH13遺伝子多型は内臓脂肪、アディポネクチン値と独立してメタボリックシンドロームに関連する2016
- Author(s)
  堀田紀久子、和田淳、宮崎茂、徳永勝人、益崎裕章、浜口和之、山田研太郎、花房俊昭、及川眞一、田中喜代次、船橋徹、松澤佑次
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン（東京都江東区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K09781
[Presentation] 非アルコール性脂肪肝疾患（NAFLD）のエピゲノム解析2015
- Author(s)
  堀田紀久子、北本卓也、北本綾、小川祐二、中島淳
- Organizer
  日本人類遺伝学会第60回大会
- Place of Presentation
  東京都新宿区
- Year and Date
  2015-10-14
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝疾患（NAFLD）のエピゲノム解析2015
- Author(s)
  堀田紀久子、北本卓也、北本綾、小川裕二、米田正人、中島　淳
- Organizer
  第2回肝臓と糖尿病・代謝研究会
- Place of Presentation
  山口県下関市
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝疾患のエピゲノム解析2015
- Author(s)
  堀田紀久子、小川祐二、本多靖、米田正人、中島淳
- Organizer
  第36回日本肥満学会
- Place of Presentation
  愛知県名古屋市
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] シンポジウム4：肥満症の成因と疫学～成因のコントロールによる効果的な予防～肥満症の遺伝素因2013
- Author(s)
  堀田紀久子
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝炎のゲノムワイド関連解析2013
- Author(s)
  堀田紀久子、中尾一和
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム（東京都千代田区）
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 特別シンポジウム4：糖尿病関連遺伝子研究の進化　肥満及び肥満症関連遺伝子2013
- Author(s)
  堀田紀久子
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] ウエスト：ヒップ比及びBMI感受性遺伝子多型の内臓脂肪および皮下脂肪面積に及ぼす効果2013
- Author(s)
  堀田紀久子、松尾知明、中田由夫、兵庫秀幸、越智秀典、蒲原聖可、小谷一晃、伊藤直人、嶺尾郁夫、和田淳、米田正人、中島淳、船橋徹、宮崎滋、徳永勝人、益崎裕章、茶山一彰、上野隆登、浜口和之、山田研太郎、花房俊昭、及川眞一、坂田利家、田中喜代次、松澤佑次、中尾一和
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] FTO、SH2B1の遺伝子多型は内臓脂肪面積と関連している2011
- Author(s)
  堀田紀久子、中田由夫、松尾知明、蒲原聖可、和田淳、小谷一晃、嶺尾郁夫、浜口和之、益崎裕章、船橋徹、宮崎滋、徳永勝人、山田研太郎、田中喜代次、花房俊昭、及川眞一、吉松博信、坂田利家、松澤佑次、中尾一和
- Organizer
  第32回日本肥満学会
- Place of Presentation
  兵庫県淡路夢舞台国際会議場
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 薬物代謝関連遺伝子群の高密度、高精度な遺伝子型決定法の確立2011
- Author(s)
  北本綾、北本卓也、水澤精穂、寺西啓、堀田紀久子、上嶋健治、小杉眞司、中尾一和、関根章博
- Organizer
  日本人類遺伝学会第56回大会
- Place of Presentation
  千葉県　幕張メッセ
- Data Source
  KAKENHI-PROJECT-23701082
[Presentation] 薬物代謝関連遺伝子群の高密度、高精度な遺伝子型決定法の確立2011
- Author(s)
  北本綾、北本卓也、水澤精穂、寺西啓、堀田紀久子、上嶋健治、小杉眞司、中尾一和、関根章博
- Organizer
  日本人類遺伝学会第56回大会
- Place of Presentation
  千葉県　幕張メッセ
- Data Source
  KAKENHI-PROJECT-23791027
[Presentation] PNPLA3遺伝子上のrs738409と非アルコール性脂肪肝炎とのケース・コントロール相関解析2011
- Author(s)
  堀田紀久子、北本卓也、北本綾、米田正人、中島淳、上野登隆、兵庫秀幸、越智秀典、茶山一彰、関根章博、中尾一和
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道さっぽろ芸術文化の館
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] NRXN3、TFAP2B、MSRA、LYPLAL1、FTO、MC4R遺伝子多型と内臓脂肪面積、皮下脂肪面積との相関2011
- Author(s)
  堀田紀久子、船橋徹、嶺尾郁夫、和田淳、浜口和之、益崎裕章、吉松博信、坂田利家、花房俊昭、松澤佑次、中尾一和
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] PNPLA3遺伝子上のrs738409と非アルコール性脂肪肝炎とのケース・コントロール相関解析2011
- Author(s)
  堀田紀久子、北本卓也、北本綾、米田正人、中島淳、上野登隆、兵庫秀幸、越智秀典、茶山一彰、関根章博、中尾一和
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道　さっぽろ芸術文化の館
- Data Source
  KAKENHI-PROJECT-23701082
[Presentation] FTO、SH2B1の遺伝子多型は内臓脂肪面積と関連している2011
- Author(s)
  堀田紀久子、中田由夫、松尾知明、蒲原聖可、和田淳、小谷一晃、嶺尾郁夫、浜口和之、益崎裕章、船橋徹、宮崎滋、徳永勝人、山田研太郎、田中喜代次、花房俊昭、及川眞一、吉松博信、坂田利家、松澤佑次、中尾一和
- Organizer
  第32回日本肥満学会
- Place of Presentation
  兵庫県淡路市
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] PNPLA3遺伝子上のrs738409と非アルコール性脂肪肝炎とのケース・コントロール相関解析2011
- Author(s)
  堀田紀久子、北本卓也、北本綾、米田正人、中島淳、上野登隆、兵庫秀幸、越智秀典、茶山一彰、関根章博、中尾一和
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道　さっぽろ芸術文化の館
- Data Source
  KAKENHI-PROJECT-23791027
[Presentation] PNPLA3遺伝子上のrs738409と非アルコール性脂肪肝炎とのケース・コントロール相関解析2011
- Author(s)
  堀田紀久子、北本卓也、北本綾、米田正人、中島淳、上野隆登、兵庫秀幸、越智秀典、茶山一彰、関根章博、中尾一和
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-21
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] NRXN3、TFAP2B、MSRA、LYPLALI、FTO、MC4R遺伝子多型と内臓脂肪面積、皮下脂肪面積との相関2011
- Author(s)
  堀田紀久子、船橋徹、嶺尾郁夫、和田淳、浜口和之、益崎裕章、吉松博信、坂田利家、花房俊昭、松澤佑次、中尾一和
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  兵庫県神戸国際会議場
- Year and Date
  2011-04-23
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 欧米人で同定された肥満感受性領域の日本人における検討2010
- Author(s)
  堀田紀久子、中田由夫、松尾知明、蒲原聖可、和田淳、小谷一晃、嶺尾郁夫、浜口和之、益崎裕章、船橋徹、宮崎滋、徳永勝人、田中喜代次、山田研太郎、花房俊昭、及川眞一、吉松博信、坂田利家、松澤佑次、中尾一和
- Organizer
  第31回日本肥満学会
- Place of Presentation
  群馬県前橋市前橋テルサ
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] メタボリックシンドローム関連遺伝子の同定2010
- Author(s)
  堀田紀久子、中田由夫、松尾知明、蒲原聖可、和田淳、伊藤直人、嶺尾郁夫、浜口和之、船橋徹、宮崎滋、徳永勝人、益崎裕章、田中喜代次、山田研太郎、花房俊昭、及川眞一、吉松博信、中尾一和、坂田利家、松澤佑次
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県岡山市
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] メタボリックシンドローム関連遺伝子の同定2010
- Author(s)
  堀田紀久子、中田由夫、松尾知明、蒲原聖可、和田淳、伊藤直人、嶺尾郁夫、浜口和之、船橋徹、宮崎滋、徳永勝人、益崎裕章、田中喜代次、山田研太郎、花房俊昭、及川眞一、吉松博信、中尾一和、坂田利家、松澤佑次
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山県岡山市岡山コンベンションセンター
- Year and Date
  2010-05-23
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 欧米人で同定された肥満感受性領域の日本人における検討2010
- Author(s)
  堀田紀久子、中田由夫、松尾知明、蒲原聖可、和田淳、小谷一晃、嶺尾郁夫、浜口和之、益崎裕章、船橋徹、宮崎滋、徳永勝人、田中喜代次、山田研太郎、花房俊昭、及川眞一、吉松博信、坂田利家、松澤佑次、中尾一和
- Organizer
  第31回日本肥満学会
- Place of Presentation
  群馬県前橋市
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] セクレトグラニン3に結合するセクレトグラニン2の視床下部における意義2009
- Author(s)
  堀田紀久子
- Organizer
  日本肥満学会
- Place of Presentation
  静岡県浜松市
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 欧米人ゲノムワイド関連解析で同定された肥満感受性領域と日本人における高度肥満との関連2009
- Author(s)
  堀田紀久子
- Organizer
  日本人類遺伝学会
- Place of Presentation
  東京都品川区
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 非アルコール性脂肪肝障害(NAFLD)とAGTR1多型との相関解析2009
- Author(s)
  堀田紀久子、米田正人、中島淳
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 欧米人ゲノムワイド関連解析で同定された肥満感受性領域と日本人における高度肥満との関連2009
- Author(s)
  堀田紀久子、中村道大、草野律子、浜口和之、中村佑輔
- Organizer
  日本人類遺伝学会第54回大会
- Place of Presentation
  東京都品川区
- Year and Date
  2009-05-24
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] Screening of 336 single nucleotide polymorphisms(SNPs) in 85obesity-related genes revealed that MKKS and MYO9A variants are associated with metabolic syndrome2009
- Author(s)
  Hotta K, Nakamaura T. Wada J, Masuzaki H, Funahashi T, Hamaguchi K, Tanaka K, Yamada K, Hanafusa T, Oikawa S, Yoshimatsu H, Nakao K Kamatani N
- Organizer
  45th General Assembly of the European Association for the Study of Diabetes
- Place of Presentation
  Vienna, Austria
- Year and Date
  2009-10-01
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] セクレトグラニン3に結合するセクレトグラニン2の視床下部における意義2009
- Author(s)
  堀田紀久子
- Organizer
  第30回日本肥満学会
- Place of Presentation
  静岡県浜松市
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 肥満発症における視床下部の役割-遺伝子多型解析からのアプローチ2009
- Author(s)
  堀田紀久子、穂坂正博、竹内利行
- Organizer
  第82回日本内分泌学会学術総会
- Place of Presentation
  群馬県前橋市
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21591186
[Presentation] 大規模SNP解析により同定した新たな肥満関連遺伝子2007
- Author(s)
  堀田紀久子、柳谷隆宏、浜口和之、飯田有俊、斎藤督、関根章博、高橋篤、角田達彦、鎌谷直之、中村祐輔
- Organizer
  日本人類遺伝学会第52回大会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2007-09-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18591012
[Presentation] GCKR、TRIB1の遺伝子多型とメタボリックシンドローム及び非アルコール性脂肪肝疾患との関連
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人,上野隆登,兵庫秀幸,越智秀典,茶山一彰,中島淳
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎県宮崎市
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-26460999
[Presentation] 非アルコール性脂肪肝疾患感受性領域の次世代シークエンサーによるターゲットリシークエンス
- Author(s)
  堀田紀久子,北本卓也,北本綾,兵庫秀幸,越智秀典,上野隆登,茶山一彰,米田正人,小川裕二,中島淳
- Organizer
  日本人類遺伝学会第59回大会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝疾患感受性領域の次世代シークエンサーによるターゲットリシークエンス
- Author(s)
  堀田紀久子,北本卓也,北本綾,兵庫秀幸,越智秀典,上野隆登,茶山一彰,米田正人,小川裕二,中島淳
- Organizer
  日本人類遺伝学会第59回大会
- Place of Presentation
  東京都江戸川区
- Year and Date
  2014-11-19 – 2014-11-22
- Data Source
  KAKENHI-PROJECT-26460999
[Presentation] GCKR、TRIB1の遺伝子多型とメタボリックシンドローム及び非アルコール性脂肪肝疾患との関連
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人, 上野隆登,兵庫秀幸,越智秀典,茶山一彰,中島淳
- Organizer
  第35回日本肥満学会
- Place of Presentation
  宮崎県宮崎市
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝炎感受性領域の次世代シークエンサーによるターゲットリシークエンス
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人,上野隆登,兵庫秀幸,越智秀典,茶山一彰,中島淳
- Organizer
  第57回日本糖尿病学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-26460999
[Presentation] Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease.
- Author(s)
  HottaK, KitamotoT, KitamotoA, YonedaM, HyogoH, OchiH, UenoT, ChayamaK, NakajimaA.
- Organizer
  9th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  京都府京都市
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-26460999
[Presentation] 「研究成果報告書概要(欧文)」より
- Author(s)
  Kikuko Hotta, Takahiro Yanagiya, Kazuyuki Hamaguchi, Aritoshi Iida, Susumu Saito, Akihiro Sekine, Atsushi Takahashi, Tatsuhiko Tsunoda, Naoyuki Kamatani, Yusuke Nakamura
- Organizer
  The 52nd Annual Meeting of the Japan Society of Human Genetics
- Data Source
  KAKENHI-PROJECT-18591012
[Presentation] 非アルコール性脂肪肝炎感受性領域の次世代シークエンサーによるターゲットリシークエンス
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人, 上野隆登,兵庫秀幸,越智秀典,茶山一彰,中島淳
- Organizer
  第57回日本糖尿病学会
- Place of Presentation
  大阪府大阪市
- Year and Date
  2014-05-22 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] Targeted next-generation sequencing and fine linkage disequilibrium mapping reveals association of PNPLA3 and PARVB with the severity of nonalcoholic fatty liver disease
- Author(s)
  Hotta K, Kitamoto T, Kitamoto A, Yoneda M, Hyogo H, Ochi H, Ueno T, Chayama K, Nakajima A
- Organizer
  th Metabolic Syndrome, Type 2 Diabetes and Atherosclerosis Congress
- Place of Presentation
  京都府京都市
- Year and Date
  2014-09-12 – 2014-09-14
- Data Source
  KAKENHI-PROJECT-25461343
[Presentation] 非アルコール性脂肪肝疾患（NAFLD）のエピゲノム解析
- Author(s)
  堀田紀久子,北本綾,北本卓也,小川裕二,米田正人,中島淳
- Organizer
  第2回肝臓と糖尿病・代謝研究会
- Place of Presentation
  山口県下関市
- Year and Date
  2015-05-21 – 2015-05-24
- Data Source
  KAKENHI-PROJECT-26460999

1. KITAMOTO Takuya (10456882)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
2. KITAMOTO Aya (30381627)

# of Collaborated Projects: 4 results

# of Collaborated Products: 21 results
3. YANAGIYA Takahiro (40322698)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. YONEDA Masato (10423831)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
5. HYOGO Hideyuki (40397930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
6. TANABE Atsushi (30373327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. Nakajima Atsushi (30326037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
8. KOBAYASHI kaori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中谷明弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 菊地正隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 黒川優

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hotta Kikuko 堀田 紀久子

堀田 紀久子 ホッタ キクコ

HOTTA Kikuko 堀田 紀久子

Research Projects

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肝疾患の発症・進行に関連するエピゲノムネットワークの調節因子の同定Principal Investigator

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Genomic and epigenomic analysis of non-alcoholic fatty liver diseasePrincipal Investigator

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Elucidation of pathophysiology and development of diagnosis method of non-alcoholic fatty liver disease by genomic and epigenomic analysisPrincipal Investigator

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非アルコール性脂肪肝障害の発症・進行に関連する遺伝素因と環境因子の解析

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The search and prospective follow-up study of genetic predisposition and environmental factors of ectopic fat accumulationPrincipal Investigator

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Analysis of the mechanism for liver cancer developing from non-alcoholic steatohepatitis by next-generation sequencing

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Genomic analysis of caloric restricted, obese and type 2 diabetic rhesus monkeys by next-generation sequencing

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A functional analysis of novel obesity-related genes and a search for obesity-related genesPrincipal Investigator

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Functional analysis of a novel metabolic syndrome related genePrincipal Investigator

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Functional analysis of an obesity and diabetes mellitus related novel genePrincipal Investigator

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[Journal Article] Identification of differentially methylated regions associated with both liver fibrosis and hepatocellular carcinoma2024

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[Journal Article] Association of protein tyrosine phosphatase 1B gene polymorphism with the effects of weight reduction therapy on bodyweight and glycolipid profiles in obese patients2021

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[Journal Article] Novel mutation identified in Leber congenital amaurosis - a case report2020

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Hotta Kikuko 堀田紀久子

堀田紀久子ホッタキクコ

HOTTA Kikuko 堀田紀久子