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nakazawa toru  中澤 徹

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NAKAZAWA Toru  中澤 徹

中澤 徹  ナカザワ トオル

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Researcher Number 30361075
Other IDs
Affiliation (Current) 2020: 東北大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help 2015 – 2020: 東北大学, 医学系研究科, 教授
2012 – 2016: 東北大学, 医学(系)研究科(研究院), 教授
2014: 東北大学, 大学院医学系研究科, 教授
2013: 東北大学, 医学(系)研究科(研究院), 教授(Professor)
2011: 東北大学, 大学院・医学系研究科, 教授 … More
2009 – 2010: Tohoku University, 大学院・医学系研究科, 准教授
2007 – 2008: 東北大学, 大学院・医学系研究科, 講師
2007 – 2008: Tohoku University, 病院, 講師
2003: 東北大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Ophthalmology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56060:Ophthalmology-related
Except Principal Investigator
Ophthalmology / Basic Section 56060:Ophthalmology-related / Neurophysiology and muscle physiology / Organic and hybrid materials / General internal medicine(including psychosomatic medicine)
Keywords
Principal Investigator
緑内障 / 網膜神経節細胞 / 酸化ストレス / iPS / 炎症 / マウス / 神経保護治療 / サイトカイン / マイクログリア / オリゴデンドロサイト … More / drug deliverv system / ナノ粒子 / 細胞指向性治療 / drug delivery system / 視神経乳頭循環不全 / 乳頭陥凹拡大 / 軸索流障害 / カルパインインヒビター / Laser Speckle Flowgraphy / Nrf2 / カルバイン インヒビター / 細胞治療 / 歯髄 / 網膜障害 / 神経再生 / 歯髄細胞 / 低酸素培養 / 浮遊培養 / 幹細胞 / 網膜 / 神経保護 / 細胞移植 / 網膜神経説細胞 / 再生医療 / 抗酸化物質 / 活性イオウ分子種 / 糖尿病網膜症 / メタボローム解析 / 硝子体サンプル / 前房水サンプル / RNA / バイオマーカー / CAGE法 / CAGE解析 / メタボロミクス / アデノ随伴ウイルス / E-SARE / RGC / in vivoイメージング / ゲノムワイド関連解析 / CRISPR … More
Except Principal Investigator
緑内障 / 網膜 / 細胞・組織 / トランスレーショナルリサーチ / 酸化ストレス / 遺伝子治療 / ゲノム編集 / 神経保護 / 網膜色素上皮細胞 / 毛様体無色素上皮細胞 / 内向き整流性カリウムチャネル / パッチクランプ法 / クロライドチャネル / 移植・再生医療 / 再生医学 / 臨床 / 視覚 / 組織培養 / 遺伝子導入 / 樹状突起 / ニューロン・シナプス・神経回路 / 視覚情報処理 / ナノ薬剤 / 再沈法 / 抗癌薬 / 点眼薬 / ナノ抗癌薬 / ナノ点眼薬 / 薬剤ナノ粒子 / 抗がん薬 / 抗がん剤 / calpain / oxidative stress / retinal ganglion cells / glaucoma / retinal ganglion cell / glaucom / カルパイン / 漢方 / 正常眼圧緑内障 / 血流 / 当帰芍薬散 / 眼底 / 可塑性 / 視覚領野 / 網膜変性 / 視覚再建 / 神経科学 / 脳・神経 / ウィルス / アデノ随伴ウイルス / 遺伝子編集 / HDAC阻害剤 / K560 / 網膜神経節細胞 / ミトコンドリア障害 / Nrf2 / ロテノン / グリア細胞 / 網膜色素変性 / リンパ球 Less
  • Research Projects

    (21 results)
  • Research Products

    (146 results)
  • Co-Researchers

    (62 People)
  •  CRISPRスクリーニングによる緑内障感受性遺伝子の同定Principal InvestigatorOngoing

    • Principal Investigator
      中澤 徹
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tohoku University
  •  エピゲノム編集による抹消血を用いた網膜色素変性病因遺伝子の発現解析法の開発Ongoing

    • Principal Investigator
      西口 康二
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tohoku University
  •  ヒトiPS細胞キメラマウスを用いた緑内障関連遺伝子変異の病態解析Principal InvestigatorOngoing

    • Principal Investigator
      中澤 徹
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Tohoku University
  •  網膜疾患関連遺伝子の機能解析のための新規CRISPR-Cas9ベクターの開発Ongoing

    • Principal Investigator
      藤田 幸輔
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tohoku University
  •  HDAC1/2特異的阻害剤K560の神経保護作用に基づく新規緑内障治療薬の開発Ongoing

    • Principal Investigator
      俵山 寛司
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tohoku University
  •  We investigate the neuroprotective mechanisms in glaucoma against oxidative stress, the Keap1/Nrf2 pthway.Ongoing

    • Principal Investigator
      檜森 紀子
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Tohoku University
  •  統合的緑内障データベースの構築とメタボロミクスによるバイオマーカー探索Principal InvestigatorOngoing

    • Principal Investigator
      中澤 徹
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Comparison of plasticity between rod and cone visual pathways

    • Principal Investigator
      Nishiguchi Koji
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  In vivo imaging of retinal ganglion cell function using adeno-associated virusPrincipal Investigator

    • Principal Investigator
      Nakazawa Toru
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Improvement effect of tokishyakuyakusan for fundus circulation in normal tension glaucoma

    • Principal Investigator
      Takayama Shin
    • Project Period (FY)
      2014 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Tohoku University
  •  Analysis of intarocular antioxidant and development of intraocular irrigating solutionPrincipal Investigator

    • Principal Investigator
      Nakazawa Toru
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Research for blood RNA marker predicting prognosis of glaucoma focusing on the early and individualized medicine.Principal Investigator

    • Principal Investigator
      Nakazawa Toru
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Creation of novel drug nanoparticles based on the conventional reverse molecular design using poor water-soluble compounds and the efficacy evaluation

    • Principal Investigator
      KASAI HITOSHI
    • Project Period (FY)
      2013 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Organic and hybrid materials
    • Research Institution
      Tohoku University
  •  Elucidation of neuroprotective effect of calpaan inhibitor in retina and central nerve systems in the model of glaucoma

    • Principal Investigator
      Ryu Morin
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Relationship between dendritic localization of inhibitory synapses and visual information processing in mammalian retinal ganglion cells

    • Principal Investigator
      KOIZUMI Amane
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      National Institute for Physiological Sciences
  •  Development of retinal treatment with dental pulp cellsPrincipal Investigator

    • Principal Investigator
      NAKAZAWA Toru
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Development of an integrated neuroprotective treatments in glaucomaPrincipal Investigator

    • Principal Investigator
      NAKAZAWA Toru
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  ナノ粒子を用いた貪食細胞特異的治療の開発Principal Investigator

    • Principal Investigator
      中澤 徹
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Neuroprotective treatment for glaucomaPrincipal Investigator

    • Principal Investigator
      NAKAZAWA Toru
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  Development of regenerative therapy for corneal endothelial diseases

    • Principal Investigator
      NISHIDA Koji
    • Project Period (FY)
      2006 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University
  •  網膜色素上皮細胞による網膜下腔イオン環境制御機構の解明

    • Principal Investigator
      志村 雅彦
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Ophthalmology
    • Research Institution
      Tohoku University

All 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent

  • [Book] 眼科 2012年9月臨時増刊号2012

    • Author(s)
      中澤徹
    • Publisher
      神経保護治療の可能性
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Book] 特集緑内障治療の現状と課題:1原発開放隅角緑内障の治療戦略, 医薬ジャーナル2010

    • Author(s)
      中澤徹
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] 連載:眼科医にもわかる生理活性物質と眼疾患の基本: TNF, 臨床眼科2010

    • Author(s)
      中澤徹
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] IV網膜のグリア細胞はどんな働きをしているのか? 眼のサイエンス視覚の不思議2010

    • Author(s)
      中澤徹
    • Publisher
      文光堂
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] 翻訳:動画でわかる緑内障手術、第6章「弁なし一重プレートチューブシャント術」2010

    • Author(s)
      中澤徹
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] 基礎研究から難治眼疾患のブレークスルーをねらえ、緑内障の神経保護治療, 臨床眼科2010

    • Author(s)
      中澤徹
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] 特集:lower Normal Pressure Glaucoma、「神経保護治療の可能性」2010

    • Author(s)
      中澤徹
    • Total Pages
      3
    • Publisher
      Medical View Point
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] 連載:眼科医にもわかる生理活性物質と眼疾患の基本: MCP-1, 臨床眼科2010

    • Author(s)
      中澤徹
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Book] 連載:眼科医にもわかる生理活性物質と眼疾患の基本:BDNF, 臨床眼科2010

    • Author(s)
      中澤徹
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Retained plsticity and substantial recovery of rod-mediated visual acuity at the visual cortex in blind adult mice with retinal dystrophy2018

    • Author(s)
      Nishiguchi KM, Fujita K, Tokashiki N, Komamura H, Takemoto-Kimura S, Okuno H, Bito H, Nakazawa T.
    • Journal Title

      Mol Ther

      Volume: 26 Pages: 2397-2406

    • DOI

      10.1016/j.ymthe.2018.07.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04258, KAKENHI-PROJECT-16K11315, KAKENHI-PROJECT-16H06279
  • [Journal Article] Ecel1 Knockdown With an AAV2-Mediated CRISPR/Cas9 System Promotes Optic Nerve Damage-Induced RGC Death in the Mouse Retina2018

    • Author(s)
      Sato Kota、Shiga Yukihiro、Nakagawa Yurika、Fujita Kosuke、Nishiguchi Koji M.、Tawarayama Hiroshi、Murayama Namie、Maekawa Shigeto、Yabana Takeshi、Omodaka Kazuko、Katayama Shota、Feng Qiwei、Tsuda Satoru、Nakazawa Toru
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 59 Pages: 3943-3943

    • DOI

      10.1167/iovs.18-23784

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09434, KAKENHI-PROJECT-17K16956
  • [Journal Article] Association between mitochondrial DNA damage and ocular blood flow in patients with glaucoma.2018

    • Author(s)
      Inoue-Yanagimachi M, Himori N, Sato K, Kokubun T, Asano T, Shiga Y, Tsuda S, Kunikata H, Nakazawa T.
    • Journal Title

      Br J Ophthalmol

      Volume: 印刷中

    • DOI

      10.1136/bjophthalmol-2018-312356

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09435
  • [Journal Article] Traditional medicine as a potential treatment for Flammer syndrome.2017

    • Author(s)
      Kikuchi A, Shiga Y, Takayama S, Arita R, Maekawa S, Kaneko S, Himori N, Ishii T, Nakazawa T
    • Journal Title

      The EPMA journal.

      Volume: 2017 Jun; 8(2) Pages: 171-175

    • DOI

      10.1007/s13167-017-0091-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Journal Article] Topical ocular dexamethasone decreases intraocular pressure and body weight in rats2016

    • Author(s)
      K. Sato, K.M. Nishiguchi, K. Maruyama, S. Moritoh, K. Fujita, Y. Ikuta, H. Kasai, T. Nakazawa
    • Journal Title

      Journal of Negative Results in BioMedicine

      Volume: 15:5 Pages: 1-6

    • DOI

      10.1186/s12952-016-0048-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25248044
  • [Journal Article] Age- and Sex-Dependency of Laser Speckle Flowgraphy Measurements of Optic Nerve Vessel Microcirculation2016

    • Author(s)
      Aizawa N, Kunikata H, Nitta F, Shiga Y, Omodaka K, Tsuda S, Nakazawa T.
    • Journal Title

      PLoS One

      Volume: 11

    • DOI

      10.1371/journal.pone.0148812

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670751, KAKENHI-PROJECT-26462629
  • [Journal Article] Brimonidine Enhances the Electrophysiological Response of Retinal Ganglion Cells through the Trk-MAPK/ERK and PI3K Pathways in Axotomized Eyes.2016

    • Author(s)
      Masayoshi Yukita, Kazuko Omodaka, Shigeki Machida, Masayuki Yasuda, Kota Sato, Kazuichi Maruyama, Koji M Nishiguchi, Toru Nakazawa
    • Journal Title

      Current Eye Research

      Volume: 未定

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26293372
  • [Journal Article] The association between systemic oxidative stress and ocular blood flow in patients with normal-tension glaucoma.2016

    • Author(s)
      Kunikata H, Nakazawa T.
    • Journal Title

      Graefe's Archive for Clinical and Experimental Ophthalmology

      Volume: 6 Pages: 216-22

    • DOI

      10.1007/s00417-015-3203-z

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26670751, KAKENHI-PROJECT-26861434
  • [Journal Article] Transcriptome profiling of the rat retina after optic nerve transection.2016

    • Author(s)
      Masayuki Yasuda, Yuji Tanaka, Kazuko Omodaka, Koji M. Nishiguchi, Orie Nakamura, Satoru Tsuda, Toru Nakazawa
    • Journal Title

      Scientific reports

      Volume: 6

    • DOI

      10.1038/srep28736

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26293372
  • [Journal Article] Effects of traditional Japanese Kampo medicines for ocular blood flow in healthy subjects2015

    • Author(s)
      Yukihiro Shiga, Taiki Kokubun, Hideyuki Konno, Noriko Himori, Morin Ryu, Natsumi Saito, Takehiro Numata, Soichiro Kaneko, Tadashi Ishii, and Toru Nakazawa
    • Journal Title

      ICMART XVII, World Congress on Medical Acupuncture Exploring Acupuncture in Medical Science

      Volume: 1 Pages: 38-39

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Journal Article] In vivo cellular imaging of various stress/response pathways using AAV following axonal injury in mice.2015

    • Author(s)
      Kosuke Fujita, Koji M Nishiguchi, Yu Yokoyama, Yusuke Tomiyama, Satoru Tsuda, Masayuki Yasuda, Shigeto Maekawa, Toru Nakazawa
    • Journal Title

      Scientific reports

      Volume: 5 Pages: 18141-18141

    • DOI

      10.1038/srep18141

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293372
  • [Journal Article] 漢方薬の血圧、脈拍、眼底血流に対する影響の検討2015

    • Author(s)
      高山真、沼田健裕、志賀由己浩、田中淳一、黒田仁、松向寺孝臣、阿部倫明、金村政輝、中澤徹、石井正
    • Journal Title

      日本内科学会雑誌

      Volume: 104 Pages: 286-286

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Journal Article] Molecular, anatomical and functional changes in the retinal ganglion cells after optic nerve crush in mice.2015

    • Author(s)
      Yukita M, Machida S, Nishiguchi KM, Tsuda S, Yokoyama Y, Yasuda M, Maruyama K, Nakazawa T.
    • Journal Title

      Documenta ophthalmologica

      Volume: 130 Pages: 149-156

    • DOI

      10.1007/s10633-014-9478-2

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26893018, KAKENHI-PROJECT-26462677, KAKENHI-PROJECT-26293372
  • [Journal Article] Organic crystal-binding peptide : Morphology control and one-pot formation of protein-displaying organic crystals2015

    • Author(s)
      Teppei Niide, Kyohei Ozawa, Hikaru Nakazawa, Oliveira Daniel, Hitoshi Kasai, Mari Onodera, Ryutaro Asano, Izumi Kumagai, Mitsuo Umetsu
    • Journal Title

      Nanoscale

      Volume: 7 Pages: 20155-20163

    • DOI

      10.1039/c5nr06471f

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25248044, KAKENHI-PROJECT-25289290, KAKENHI-PROJECT-24000011
  • [Journal Article] 緑内障における神経保護治療2014

    • Author(s)
      津田聡、中澤徹
    • Journal Title

      Medical Science Digest

      Volume: 40 (3) Pages: 14-17

    • Data Source
      KAKENHI-PROJECT-24659756
  • [Journal Article] Molecular and cellular features of murine craniofacial and trunk neural crest cells as stem cell-like cells.2014

    • Author(s)
      Kunie Hagiwara, Takeshi Obayashi, Nobuyuki Sakayori, Emiko Yamanishi, Ryuhei Hayashi, Noriko Osumi, Toru Nakazawa, Kohji Nishida
    • Journal Title

      PLoS One.

      Volume: 9(1) Pages: 1-13

    • DOI

      10.1371/journal.pone.0084072

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-12J08042, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-25253093, KAKENHI-PROJECT-26462685
  • [Journal Article] Critical role of Nrf2 in oxidative stress-induced retinal ganglion cell death2014

    • Author(s)
      Himori N, Yamamoto K, Maruyama K, Ryu M, Taguchi K, Yamamoto M, Nakazawa T.
    • Journal Title

      J Neurochem

      Volume: 127 Pages: 669-680

    • DOI

      10.1111/jnc.12325

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592613, KAKENHI-PROJECT-24249015, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-25117703
  • [Journal Article] RNA sequence reveals mouse retinal transcriptome changes early after axonal injury.2014

    • Author(s)
      Yasuda M, Tanaka Y, Ryu M, Tsuda S, Nakazawa T
    • Journal Title

      PloS ONE

      Volume: 9(3)

    • DOI

      10.1371/journal.pone.0093258

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24700472
  • [Journal Article] The role of calpain in an in vivo model of oxidative stress-induced retinal ganglion cell damage2014

    • Author(s)
      Yu Yokoyama, Kazuichi Maruyama, Kotaro Yamamoto, Kazuko Omodaka, Masayuki Yasuda, Noriko Himori, Morin Ryu, Koji M. Nishiguchi, Toru Nakazawa
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 451 Pages: 510-515

    • DOI

      10.1016/j.bbrc.2014.08.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25462749, KAKENHI-PROJECT-26462677
  • [Journal Article] A polymeric device for controlled transscleral multi-drug delivery to the posterior segment of the eye2014

    • Author(s)
      Nobuhiro Nagai, Hirokazu Kaji, Hideyuki Onami, Yumi Ishikawa, Matsuhiko Nishizawa, Noriko Osumi, Toru Nakazawa, Toshiaki Abe
    • Journal Title

      Acta Biomater.

      Volume: 10(2) Pages: 680-687

    • DOI

      10.1016/j.actbio.2013.11.004

    • NAID

      40020425298

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23680054, KAKENHI-PROJECT-23681027, KAKENHI-PROJECT-24651156, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24791832, KAKENHI-PROJECT-26286031, KAKENHI-PROJECT-26560233
  • [Journal Article] 緑内障に対する神経保護薬の研究開発2013

    • Author(s)
      田中佑治、中澤徹
    • Journal Title

      眼科

      Volume: 55(5) Pages: 601-607

    • NAID

      40019690678

    • Data Source
      KAKENHI-PROJECT-24659756
  • [Journal Article] Molecular genetic analysis of primary open-angle glaucoma, normal tension glaucoma, and developmental glaucoma for the VAV2 and VAV3 gene variants in Japanese subjects.2013

    • Author(s)
      Shi D, Takano Y, Nakazawa T, MengkegaleM, Yokokura S, Nishida K, Fuse N.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 15;432(3) Pages: 509-512

    • DOI

      10.1016/j.bbrc.2013.02.003

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591928, KAKENHI-PROJECT-24659756
  • [Journal Article] Association of HK2 and NCK2 with normal tension glaucoma in the Japanese population.2013

    • Author(s)
      Shimizu A, Takano Y, Shi D, Yokokura S,Yokoyama Y, Zheng X, Shiraishi A, Ohashi Y, Nakazawa T, Fuse N.
    • Journal Title

      PLoS One.

      Volume: 18 Pages: 1-11

    • DOI

      10.1371/journal.pone.0054115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22591928, KAKENHI-PROJECT-23592556, KAKENHI-PROJECT-24659756
  • [Journal Article] Development of Azo-Based Fluorescent Probes to Detect Different Levels of Hypoxia.2013

    • Author(s)
      Wen Piao, Satoru Tsuda, Yuji Tanaka, Satoshi Maeda, Fengyi Liu, Shodai Takahashi, Yu Kushida, Toru Komatsu, Tasuku Ueno Takuya Terai, Toru Nakazawa, Masanobu Uchiyama, Keiji Morokuma, Tetsuo Nagano, KenjiroHanaoka
    • Journal Title

      Angew Chem Int Ed Engl

      Volume: 52 Pages: 13028-13032

    • DOI

      10.1002/anie.201305784

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-13J10749, KAKENHI-PROJECT-22000006, KAKENHI-PROJECT-23685004, KAKENHI-PROJECT-24655147, KAKENHI-PROJECT-24659042, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24689003, KAKENHI-PROJECT-24700472
  • [Journal Article] Critical role of calpain in axonal damage-induced retinal ganglion cell death.2012

    • Author(s)
      Molin Ryu, Toru Nakazawa, et al
    • Journal Title

      J Neurosci Res.

      Volume: 90 Pages: 802-815

    • DOI

      10.1002/jnr.22800

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045, KAKENHI-PROJECT-22700379, KAKENHI-PROJECT-24659756
  • [Journal Article] Metabolic stress response implicated in diabetic retinopathy: the role of calpain, and the therapeutic impact of calpain inhibitor2012

    • Author(s)
      Shanab AY, Nakazawa T, Ryu M, Tanaka Y, Himori N, Taguchi K, Ysuda M, Watanabe R, Takano J, Saido T, Minegishi N, Miyata T, Abe T, Yamamoto M.
    • Journal Title

      Neurobiol Dis.

      Volume: 48 Pages: 556-557

    • DOI

      10.1016/j.nbd.2012.07.025

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591404, KAKENHI-PROJECT-24659756, KAKENHI-PROJECT-24700472, KAKENHI-PROJECT-24790307, KAKENHI-PUBLICLY-23117503
  • [Journal Article] Progression of Visual Field Defects in Eyes With Different Optic Disc Appearances in Patients With Normal Tension Glaucoma2012

    • Author(s)
      Toru Nakazawa, et al
    • Journal Title

      J Glaucoma

      Volume: (未定)(In press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] The Regulatory Roles of Apoptosis-Inducing Factor in the Formation and Regression Processes of Ocular Neovascularization.2012

    • Author(s)
      Hisatomi T
    • Journal Title

      The American Journal of Pathology.

      Volume: 181 Pages: 53-61

    • DOI

      10.1016/j.ajpath.2012.03.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24249083, KAKENHI-PROJECT-24659756
  • [Journal Article] Progression of visual field defects in eyes with different optic disc appearances in patients with normal tension glaucoma2012

    • Author(s)
      Nakazawa T, Shimura M, Ryu M, Himori N, Nitta F, Omodaka K, Doi H, Yasui T, Fuse N, Nishida K
    • Journal Title

      J Glaucoma

      Volume: (印刷中)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Tumor necrosis factor-alpha mediates photoreceptor death in a rodent model of retinal detachment2011

    • Author(s)
      Toru Nakazawa, et al
    • Journal Title

      Invest ophthalmol Vis Sci

      Volume: 52 Pages: 1384-1391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Association between optic nerve blood flow and objective examinations in glaucoma patients with generalized enlargement disc type2011

    • Author(s)
      Chiba N, Omodaka K, Yokoyama Y, Aizawa N, Tsuda S, Yasuda M, Otomo T, Yokokura S, Fuse N, Nakazawa T
    • Journal Title

      Clin Ophthalmol

      Volume: 5 Pages: 1549-56

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Reproducibility of ocular circulation measurements obtained using Laser Speckle Flowgraphy-NAVI in patients with glaucoma2011

    • Author(s)
      Aizawa N, Yokoyama Y, Chiba N, Omodaka K, Yasuda M, Otomo T, Nakamura, M, Fuse N, Nakazawa T
    • Journal Title

      Clin Ophthalmol

      Volume: 5 Pages: 1171-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Significant correlations between optic nerve head microcirculation and visual field defects and nerve fiber layer loss in glaucoma patients with myopic glaucomatous disk2011

    • Author(s)
      Yokoyama Y, . Aizawa N, Chiba N, Omodaka K, Nakamura M, Otomo T, Yokokura S, Fuse N, and Nakazawa T
    • Journal Title

      Clin Ophthalmol.

      Volume: 5 Pages: 1721-1727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Visual outcome after intravitreal triamcinolone acetonide depends on optical coherence tomographic patterns in patients with diffuse diabetic macular edema2011

    • Author(s)
      Shimura M, Yasuda K, Nakazawa, T, Hiranon Y, Sakamoto T, Ogura, Y, Shiono T
    • Journal Title

      Retina

      Volume: 31 Pages: 1729-1732

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] The critical role of calpain in axonal damage-induced retinal ganglion cell death2011

    • Author(s)
      Ryu M, Yasuda M, Shi D, Shanab AY, Watanabe R, Himori N, Omodaka K, Yokoyama Y, Takano J, Saido T, Nakazawa T
    • Journal Title

      J Neurosci Res

      Volume: 5 Pages: 1721-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Eeproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma2011

    • Author(s)
      Nahoko Aizawa, Toru Nakazawa, et al
    • Journal Title

      Am J Ophthalmol

      Volume: 5 Pages: 1171-1176

    • DOI

      10.2147/opth.s22093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Association between optic nerve blood flow and objective examinations in glaucoma patients with generalized enlargement disc type2011

    • Author(s)
      Naoki Chiba, Toru Nakazawa, et al
    • Journal Title

      Clinical Ophthalmology

      Volume: 5 Pages: 1549-1556

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Over 10 years follow-up of Coats' disease in adulthood2011

    • Author(s)
      Otani T, Yasuda K, Aizawa N, Sakai F, Nakazawa T, Shimura M
    • Journal Title

      Clin Ophthalmol

      Volume: 5 Pages: 1729-32

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Pre-seasonal Treatment With Topical Olopatadiae Suppresses the Clinical Symptoms of Seasonal Allergic Conjunctivitis2011

    • Author(s)
      Shimura Masahiko, Toru Nakazawa, et al
    • Journal Title

      Am J Ophthalmol

      Volume: 151 Pages: 697-702

    • DOI

      10.1016/j.ajo.2010.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Significant correlations between optic nerve head microcirculation and visual field defects and nerve fiber layer loss in glaucoma patients with myopic glaucomatous disk2011

    • Author(s)
      Yu Yokoyama, Toru Nakazawa, et al
    • Journal Title

      Clinical Ophthalmology

      Volume: 5 Pages: 1721-1727

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Tumor Necrosis Factor-{alpha} Mediates Photoreceptor Death in a Rodent Model of Retinal Detachment.2011

    • Author(s)
      Nakazawa T, Kayama M, RyuM, et al.
    • Journal Title

      Investigative Ophthalmology and Visual Science.

      Volume: 52(3) Pages: 1384-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659395
  • [Journal Article] Over 10 years foUowup of Coats' disease in adulthood2011

    • Author(s)
      Tatsuro Otani, Toru Nakazawa, et al
    • Journal Title

      Clinical Ophthalmology

      Volume: 5 Pages: 1729-1732

    • DOI

      10.2147/opth.s27938

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Successful removal of large intraocular foreign body by 25-gauge microincision vitrectomy surgery2011

    • Author(s)
      Hiroshi Kunikata, Toru Nakazawa, et al
    • Journal Title

      J Ophthalmol

    • DOI

      10.1155/2011/940323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Suppression of phagocytic cells in retinal disorders using amphiphilic poly(y-glutamic acid)nanoparticles containing dexamethasone.2011

    • Author(s)
      Morin Ryu, Toru Nakazawa, TakamiAkagi, et al.
    • Journal Title

      Journal of controlled release.

      Volume: 151(1) Pages: 65-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659395
  • [Journal Article] Heat Shock Protein 70 is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase2011

    • Author(s)
      Kayama M, Nakazawa T, et al.
    • Journal Title

      American Journal of Pathology.

      Volume: 178(3) Pages: 1080-91

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21659395
  • [Journal Article] Suppression of phagocytic cells in retinal disorders using amphiphilic poly (Y-glutamic acid) nanoparticles containing dexamethasone2011

    • Author(s)
      Molin Ryu, Toru Nakazawa, et al
    • Journal Title

      J Control Release

      Volume: 151 Pages: 65-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Heat shock protein 70 (HSP70) is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase2011

    • Author(s)
      Maki Kayama, Toru Nakazawa, et al
    • Journal Title

      Am J pathol

      Volume: 178 Pages: 1080-1091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Pre-seasonal treatment with topical olopatadine suppresses the clinical symptoms of seasonal allergic conjunctivitis.2011

    • Author(s)
      Shimura M, Yasuda K, Miyazawa A, Otani T, Nakazawa T.
    • Journal Title

      Am J Ophthalmol

      Volume: 151(4) Pages: 697-702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Tumor Necrosis Factor-α Mediates Photoreceptor Death in a Rodent Model of Retinal Detachment2011

    • Author(s)
      Nakazawa T, Kayama M, Ryu M, Kunikata H, Watanabe R, Yasuda M, Kinugawa J, Vavvas D, Miller JW
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 52 Pages: 1384-1391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Suppression of phagocytic cells in retinal disorders using amphiphilic poly(γ-glutamic acid)nanoparticles containing dexamethasone2011

    • Author(s)
      Ryu M, Nakazawa T, Akagi T, Tanaka T, Watanabe R, Yasuda M, Himori N, Maruyama K, Yamashita T, Abe T, Akashi M, Nishida K
    • Journal Title

      J Control Release

      Volume: 151 Pages: 65-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Successful Removal of Large Intraocular Foreign Body by 25-Gauge. Microincision Vitrectomy Surgery.2011

    • Author(s)
      Kunikata H, Uematsu M, Nakazawa T, Fuse N
    • Journal Title

      J Ophthalmology.

      Pages: 940323-940323

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Heat Shock Protein 70 is critical for the photoreceptor stress response after retinal detachment via modulating anti-apoptotic Akt kinase2011

    • Author(s)
      Kayama M, Nakazawa T, Thanos A, Morizane Y, Murakami Y, Theodoropoulou S, Abe T, Vavvas M, Miller JW
    • Journal Title

      Am J Pathol

      Volume: 178 Pages: 1080-1091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Journal Article] Vascular Adhesion Protein-1 Blockade Suppresses Choroidal Neovascul arization2008

    • Author(s)
      Noda K, She H, Nakazawa T, et.al.
    • Journal Title

      FASEB J. 22

      Pages: 2928-2935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicity for amacrine cells.2008

    • Author(s)
      Nakazawa T, 他, 7名
    • Journal Title

      J Neurosci Res. 87

      Pages: 1412-1423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Visual prognosis and vitreous cytokine levels after arteriovenous sheathotomy in branch retinal vein occlusion associated with macular oedema2008

    • Author(s)
      Shimura M, Nakazawa T, Yasuda K, Kunikata H, Shiono T, Nishida K
    • Journal Title

      Acta Ophthalmol 86

      Pages: 377-384

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390468
  • [Journal Article] Self-protective roles of Muller cells during NMDA-induced retinal damage through activation of ERK signaling pathway.2008

    • Author(s)
      Nakazawa T, 他, 6名
    • Journal Title

      J Neurosci Res. 86

      Pages: 136-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] A Novel mechanism of HIV protease inhibitors for neuroprotection through inhibition of mitochondrial apoptosis.2008

    • Author(s)
      Hisatomi T, Nakazawa T, 他, 13名
    • Journal Title

      J Clin Invest. 118

      Pages: 2025-2038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] A Novel mechanism of HIV protease inhibitors for neuroprotection through inhibition of mitochondrial apoptosis2008

    • Author(s)
      Hisatomi T, Nakazawa T
    • Journal Title

      J Clin Invest. 118

      Pages: 2025-2038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Self-protective roles of Muller cells during NMDA-induced retinal damage through activation of ERK signaling pathway2008

    • Author(s)
      Nakazawa T, et.al.
    • Journal Title

      J Neurosci Res. 86

      Pages: 136-144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Calpain-mediated degradation of G-substrate plays a critical role in retinal excitotoxicitv for amacrine cells2008

    • Author(s)
      Nakazawa T, et.al.
    • Journal Title

      J Neurosci Res. 87

      Pages: 1412-1423

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Inhibition of vascular adhesion protein-1 suppresses endotoxin-induced uveitis2008

    • Author(s)
      Noda K, Miyahara S, Nakazawa T, et.al.
    • Journal Title

      FASEB J 22

      Pages: 1094-1103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Vascular Adhesion Protein-1 Blockade Suppresses Choroidal Neovascularization.2008

    • Author(s)
      Noda K, She H, Nakazawa T, 他, 12名
    • Journal Title

      FASEB J. 22

      Pages: 2928-2935

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Dexamethasone Reduces Photoreceptor Damage Caused by Photodynamic Therapy in a Rat Model of Choroidal Neovascularization.2008

    • Author(s)
      She H, Nakazawa T, 他, 7名
    • Journal Title

      Invest Ophthalmol Vis Sci. 49

      Pages: 5008-5014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Inhibition of vascular adhesion protein-1 suppresses endotoxin-induced uveitis.2008

    • Author(s)
      Noda K, Miyahara S, Nakazawa T, 他, 11名
    • Journal Title

      FASEB J. 22

      Pages: 1094-1103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Dexamethasone Reduces Photoreceptor Damage Caused by Photodynami c Therapy in a Rat Model of Choroidal Neovascularization2008

    • Author(s)
      She H, Nakazawa T, et.al.
    • Journal Title

      Invest Ophthalmol Vis Sci. 49

      Pages: 5008-5014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Evaluation of LOXL1 polymorphisms in eyes with exfoliation glaucoma in Japanese2008

    • Author(s)
      Fuse N, Miyazawa A, Nakazawa T, Mengkegale M, Otomo T, Nishida K
    • Journal Title

      Mol Vis 14

      Pages: 1388-1343

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390468
  • [Journal Article] Comparative therapy evaluation of intravitreal bevacizumab and triamcinolone acetonide on persistent diffuse diabetic macular edema.2008

    • Author(s)
      Shimura M, Nakazawa T, Yasuda K, Shiono T, Iida T, Sakamoto T, Nishida K
    • Journal Title

      Am J Ophthalmol 145

      Pages: 854-861

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390468
  • [Journal Article] Pitavastatin Prevents NMDA-Induced Retinal Ganglion Cell Death By Suppressing Leukocyte Recruitment.2007

    • Author(s)
      Nakazawa Toru
    • Journal Title

      Journal of Neurochemistry 100

      Pages: 1018-1031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin.2007

    • Author(s)
      Nakazawa T, 他, 9名
    • Journal Title

      Invest Ophthalmol Vis Sci. 48

      Pages: 2760-2768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Monocytes Chemoattractant Protein-1 mediates retinal detachment-induced photoreceptor loss.2007

    • Author(s)
      Nakazawa T, 他, 12名
    • Journal Title

      Proc Natl Acad Sci U S A. 104

      Pages: 2425-2430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Inhibition of nitric oxide synthetase reduces photoreceptor degeneration caused by photodynamic therapy in a model of choroidal neovascularization.2007

    • Author(s)
      She H, Nakazawa T, 他, 5名
    • Journal Title

      Invest Ophthalmol Vis Sci. 48

      Pages: 2268-2277

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Attenuated glial reactions and photoreceptor degeneration after retinal detachment in mice deficient in glial fibrillary acidic protein and vimentin.2007

    • Author(s)
      Nakazawa Toru
    • Journal Title

      Invest Ophthalmol Vis Sci 48

      Pages: 2760-2768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Pitavastatin Prevents NMDA-Induced Retinal Ganglion Cell Death By Suppressing Leukocyte Recruitment.2007

    • Author(s)
      Nakazawa T, 他, 7名
    • Journal Title

      J Neurochem. 100

      Pages: 1018-1031

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Journal Article] Monocytes Chemoattractant Protein-1 mediates retinal detach ment-induced photoreceptor loss.2007

    • Author(s)
      Nakazawa Toru
    • Journal Title

      Proc Natl Acad Sci USA 104

      Pages: 2425-2430

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Patent] 新規抗酸化眼内灌流液2015

    • Inventor(s)
      中澤徹、赤池孝章、國方彦志
    • Industrial Property Rights Holder
      東北大学
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-09-30
    • Data Source
      KAKENHI-PROJECT-26670751
  • [Patent] 眼疾患治療用ナノ粒子化製剤2015

    • Inventor(s)
      青柳重信, 稲田愉, 渋谷博, 笠井均, 中澤徹
    • Industrial Property Rights Holder
      大内新興化学工業株式会社, 国立大学法人東北大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2015-006212
    • Filing Date
      2015-01-15
    • Data Source
      KAKENHI-PROJECT-25248044
  • [Patent] 視神経障害発祥リスクの判定方法2014

    • Inventor(s)
      田中佑治、安田正幸、面高宗子、中澤徹
    • Industrial Property Rights Holder
      田中佑治、安田正幸、面高宗子、中澤徹
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2014-017481
    • Filing Date
      2014-01-31
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] MMWINを活用したデータベースの構築、病診連携システムの確立2018

    • Author(s)
      檜森紀子、國方彦志、加藤圭一、吉田清香、志賀由己浩、斎藤慶治、中山雅晴、中澤徹
    • Organizer
      第29回緑内障学会
    • Data Source
      KAKENHI-PROJECT-18K09435
  • [Presentation] The association between oxidative stress and circumpapillary retinal nerve fiber layer thickness in patients with normal-tension glaucoma2018

    • Author(s)
      Noriko Himori, Taiki Kokubun, Yukihiro Shiga, Kazuko Omodaka, Hiroshi Kunikata, Toru Nakazawa
    • Organizer
      ARVO Annual meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K09435
  • [Presentation] 漢方薬の血圧、脈拍、眼底血流に対する影響の検討2015

    • Author(s)
      高山真、沼田健裕、志賀由己浩、田中淳一、黒田仁、松向寺孝臣、阿部倫明、金村政輝、中澤徹、石井正
    • Organizer
      第112回日本内科学会講演会(2015)
    • Place of Presentation
      京都、みやこめっせ
    • Year and Date
      2015-04-10
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Presentation] Effects of traditional Japanese Kampo medicines for ocular blood flow in healthy subjects2015

    • Author(s)
      Shin Takayama, Yukihiro Shiga, Taiki Kokubun, Hideyuki Konno, Noriko Himori, Morin Ryu, Natsumi Saito, Takehiro Numata, Soichiro Kaneko, Tadashi Ishii, and Toru Nakazawa
    • Organizer
      International Congress of Medical Acupuncture and Related Techniques 2015
    • Place of Presentation
      Indonesia, Bali
    • Year and Date
      2015-05-08
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Presentation] 漢方薬内服による血圧、脈拍、眼底血流に対する影 響の検討2015

    • Author(s)
      高山 真, 沼田 健裕, 志賀 由己浩, 田中 淳 一, 黒田 仁, 阿部 倫明, 金村 政輝, 中澤 徹, 石井 正
    • Organizer
      第112回日本内科学会総会・講演会
    • Place of Presentation
      みやこめっせ(京都)
    • Year and Date
      2015-04-12
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Presentation] 疎水性置換基により修飾した薬理活性物質のナノ粒子化2014

    • Author(s)
      小関良卓, 幾田良和, 村上達也, 田中佑治, 中澤徹, 小野寺恒信, 及川英俊, 笠井均
    • Organizer
      2014PHyMシンポジウム
    • Place of Presentation
      仙台
    • Year and Date
      2014-06-06
    • Data Source
      KAKENHI-PROJECT-25248044
  • [Presentation] 近未来の緑内障神経保護治療へのアプローチ2013

    • Author(s)
      中澤徹
    • Organizer
      ファガン発売1周年記念講演 in 千葉
    • Place of Presentation
      幕張
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] RNA-Seqによるマウス視神経挫滅極早期における網膜網羅的遺伝子発現定量解析2013

    • Author(s)
      田中佑治、安田正幸、中澤徹
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 基礎研究を踏まえた夢のある近未来治療2013

    • Author(s)
      中澤徹
    • Organizer
      広島大学・山口大学眼科Grand Rounds
    • Place of Presentation
      山口
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 緑内障、神経保護治療からのアプローチ2013

    • Author(s)
      中澤徹
    • Organizer
      函館眼科医会学術講演会
    • Place of Presentation
      函館
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 低酸素応答生理活性蛍光プローブを用いた網膜低酸素領域のin vivo イメージング2013

    • Author(s)
      津田聡、田中佑治、朴文、國方彦志、横山悠、安田正幸、花岡健二郎、長野哲雄、中澤徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] ナノ粒子による副腎皮質ステロイド治療薬開発2013

    • Author(s)
      中澤徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 視神経挫滅モデルにおけるROCK阻害薬K-115の神経保護効果2013

    • Author(s)
      山本耕太郎、丸山和一、檜森紀子、中澤徹
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 酸化ストレスによる網膜神経節細胞死におけるカルパインの働き2013

    • Author(s)
      横山悠、劉孟林、山本耕太郎、安田正幸、田中佑治、丸山和一、中澤徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] エリスロポエチンノックアウトマウスを用いた網膜・視神経の組織学的検討2013

    • Author(s)
      安田正幸、劉孟林、田中佑治、檜森紀子、面高宗子、横山悠、雪田昌克、津田聡、 丸山和一、山本雅之、中澤 徹
    • Organizer
      第117回日本眼科学会総会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] Advances in basic sciences: implications for clinical management of glaucoma2012

    • Author(s)
      中澤徹
    • Organizer
      The 1st Asia-Pacific Glaucoma Congress (APGC2012)
    • Place of Presentation
      バリ インドネシア
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 避難所往診体制の総括と問題点2011

    • Author(s)
      Neuroprotective treatment for glaucoma、中澤徹など
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      金沢
    • Year and Date
      2011-09-28
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] NTGにおける神経保護治療戦略.(招待講演)2011

    • Author(s)
      Toru Nakazawa, et al
    • Organizer
      Santen Private Seminar
    • Place of Presentation
      Paris, France
    • Year and Date
      2011-06-28
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Establish the drug delivery system for the suppression of phagocytic cells with nanoparticles2011

    • Author(s)
      Toru Nakazawa
    • Organizer
      EGA2011
    • Place of Presentation
      Gyeongju, Korea(招待講演)
    • Year and Date
      2011-06-12
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Critical role of Nrf2 in the oxidative stress-induced retinal ganglion2011

    • Author(s)
      Toru Nakazawa et al.
    • Organizer
      ARVO2011
    • Place of Presentation
      Ft. Lauderdale FL, U. S. A
    • Year and Date
      2011-05-03
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 神経(New論)保護治療の可能性について2011

    • Author(s)
      中澤徹
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      秋田(招待講演)
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Neuroprotective treatment for glaucoma2011

    • Author(s)
      中澤徹
    • Organizer
      第54回日本神経化学会大会
    • Place of Presentation
      金沢
    • Year and Date
      2011-09-28
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Critical role of Nrf2 in the oxidative stress-induced retinal ganglion2011

    • Author(s)
      Toru Nakazawa
    • Organizer
      AEVO2011
    • Place of Presentation
      Ft.Lauderdale FL, U.S.A
    • Year and Date
      2011-05-03
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 緑内障と酸化ストレス2011

    • Author(s)
      中澤徹など
    • Organizer
      第11回日本抗加齢医学学会総会
    • Place of Presentation
      京都
    • Year and Date
      2011-05-28
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 避難所往診体制の総括と問題点2011

    • Author(s)
      中澤徹
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      秋田
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 神経(New論)保護治療の可能性について(招待講演)2011

    • Author(s)
      中澤徹など
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      秋田
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] NTGにおける神経保護治療戦略2011

    • Author(s)
      Toru Nakazawa
    • Organizer
      Santen Private Seminar
    • Place of Presentation
      Paris, France(招待講演)
    • Year and Date
      2011-06-28
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Establish the drug delivery system for the suppression of phagocytic cells with nanoparticles.(招待講演)2011

    • Author(s)
      Toru Nakazawa, et al.
    • Organizer
      EGA2011
    • Place of Presentation
      yeongju, Korea
    • Year and Date
      2011-06-12
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 軸索障害による網膜神経節細胞死の基礎的実験成果2011

    • Author(s)
      中澤徹など
    • Organizer
      第24回日本緑内障学会
    • Place of Presentation
      秋田
    • Year and Date
      2011-09-24
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] γPGAナノ粒子による内眼炎ステロイド治療2011

    • Author(s)
      中澤徹など
    • Organizer
      第31回日本眼薬理学会
    • Place of Presentation
      松江
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] レーザースペックル眼底血流計のGE型乳頭を持つ緑内障患者における他覚的検査としての有用性2010

    • Author(s)
      千葉真生、中澤徹など
    • Organizer
      第21回日本緑内障学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Association of optic nerve head blood flow and optic disc structure in the normal and glaucoma patients2010

    • Author(s)
      Naoki Chiba, Toru Nakazawa, et al
    • Organizer
      Asia-Pacific Joint Glaucoma Congress (APJGC) 2010
    • Place of Presentation
      Taipei, Taiwan
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] OCTによる網膜神経線維層厚とHRTII乳頭パラメータとの相関2010

    • Author(s)
      中澤徹など
    • Organizer
      第21回日本緑内障学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] The development of new glaucoma mice model with the obstruction of axonal flow2010

    • Author(s)
      Toru Nakazawa, et al
    • Organizer
      日本神経科学学会 Neuro2010
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 近視型乳頭を伴う正常眼圧緑内障におけるOCT, レーザースペックルを用いた他覚的検査の有用性2010

    • Author(s)
      中澤徹など
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Dexamethasone suppresses retinal detachment-induced cytokines expression and photoreceptor loss2010

    • Author(s)
      Toru Nakazawa, Morin Ryu, et al
    • Organizer
      2010 ARVO Annual Meeting
    • Place of Presentation
      アメリカ フロリダ マイアミ市
    • Data Source
      KAKENHI-PROJECT-21659395
  • [Presentation] 近視型乳頭を伴う正常眼圧緑内障におけるOCT,レーザースペックルを用いた他覚的検査の有用性2010

    • Author(s)
      中澤徹, など
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] A NEW RESEARCH MODEL OF NORMAL TENSION GLAUCOMA BY BLOCKING AXOPLASMIC TRANSPORT OF RETINAL GANGLION CELLS2010

    • Author(s)
      Morin Ryu, Toru Nakazawa, et al
    • Organizer
      Asia-Pacific Joint Glaucoma Congress (APJGC)2010
    • Place of Presentation
      Taipei, Taiwan.
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Analysis of HSP70 in the retinal detachment2010

    • Author(s)
      Maki Kayama, Toru Nakazawa
    • Organizer
      2010 ARVO Annual Meeting
    • Place of Presentation
      アメリカ フロリダ マイアミ市
    • Data Source
      KAKENHI-PROJECT-21659395
  • [Presentation] 緑内障病期別にみたレーザースペックルフローグラフィーによる視神経乳頭循環の比較2010

    • Author(s)
      相澤奈帆子、中澤徹など
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] Association of optic nerve head blood flow and optic disc structure in the normal and glaucoma patients2010

    • Author(s)
      Naoki Chiba, Toru Nakazawa, et al
    • Organizer
      Asia-Pacific Joint Glaucoma Congress (APJGC)2010
    • Place of Presentation
      Taipei, Taiwan
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] A NEW RESEARCH MODEL OF NORMAL TENSION GLAUCOMA BY BLOCKING AXOPLASMIC TRANSPORT OF RETINAL GANGLION CELLS2010

    • Author(s)
      Morin Ryu, Toru Nakazawa, et al
    • Organizer
      Asia-Pacific Joint Glaucoma Congress (APJGC) 2010
    • Place of Presentation
      Taipei, Taiwan
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 軸索流低下による新しい正常眼圧緑内障モデル2010

    • Author(s)
      中澤徹など
    • Organizer
      第64回日本臨床眼科学会
    • Place of Presentation
      神戸市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] 蛍光眼底造影とレーザースペックルフローグラフィーによる乳頭循環の比較2010

    • Author(s)
      相澤奈帆子、中澤徹など
    • Organizer
      第21回日本緑内障学会
    • Place of Presentation
      福岡市
    • Data Source
      KAKENHI-PROJECT-22689045
  • [Presentation] ステロイド含有γPGAナノ粒子の特異的薬剤送達機能とその治療効果2009

    • Author(s)
      劉孟林, 中澤徹
    • Organizer
      日本眼科学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2009-04-16
    • Data Source
      KAKENHI-PROJECT-21659395
  • [Presentation] ミクログリア機能と緑内障-病因と治療-2009

    • Author(s)
      中澤 徹
    • Organizer
      第82回日本薬理学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-03-18
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] マウス高眼圧モデルにおけるTNFaを介したオリゴデンドロサイト細胞死と網膜神経節細胞死2008

    • Author(s)
      中澤 徹
    • Organizer
      日本眼科学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-04-09
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] TNFα mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma2008

    • Author(s)
      中澤 徹
    • Organizer
      Neuroscience 2008
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-07-09
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] 角膜輪部腫瘍性病変の外科的治療2008

    • Author(s)
      中澤 徹
    • Organizer
      第112回日本眼科学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-04-20
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] 緑内障治療の基礎と臨床2008

    • Author(s)
      中澤 徹
    • Organizer
      第112回日本緑内障学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2008-09-13
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] 正常眼圧緑内障の視神経乳頭形状とMD slopeの相関2008

    • Author(s)
      中澤 徹
    • Organizer
      第62回日本臨床眼科学会
    • Place of Presentation
      東京国際フォーラム
    • Year and Date
      2008-10-24
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] 網膜障害モデルにおけるミューラー細胞を介した神経保護作用2008

    • Author(s)
      中澤 徹
    • Organizer
      第112回日本眼科学会総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2008-04-19
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] マウス高眼圧モデルにおけるTNFaを介したオリゴデンドロサイト細胞死と網膜神経節細胞死2007

    • Author(s)
      中澤 徹
    • Organizer
      日本眼科学会
    • Place of Presentation
      大阪国際会議場
    • Year and Date
      2007-04-20
    • Data Source
      KAKENHI-PROJECT-19791255
  • [Presentation] 緑内障における役者たち、細胞レベルの考察

    • Author(s)
      中澤徹
    • Organizer
      第16回甲信セミナー
    • Place of Presentation
      甲府
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 緑内障神経保護治療

    • Author(s)
      中澤徹
    • Organizer
      Tokyo Ophthalmology Club
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 疎水性置換基としてコレステロールを導入したナノ薬剤の作製・サイズ制御および薬効評価

    • Author(s)
      小関良卓, 幾田良和, 村上達也, 田中佑治, 中澤徹, 小野寺恒信, 及川英俊, 笠井均
    • Organizer
      化学系学協会東北大会
    • Place of Presentation
      米沢
    • Year and Date
      2014-09-20 – 2014-09-21
    • Data Source
      KAKENHI-PROJECT-25248044
  • [Presentation] Effects of traditional Kampo medicines for ocular blood flow in healthy subjects

    • Author(s)
      Shin Takayama, Yukihiro Shiga, Taiki Kokubun, Hideyuki Konno, Noriko Himori, Morin Ryu, Takehiro Numata, Soichiro Kaneko, Tadashi Ishii, and Toru Nakazawa
    • Organizer
      International Council of Medical Acupuncture and Related Techniques
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2015-05-08 – 2015-05-10
    • Data Source
      KAKENHI-PROJECT-26460897
  • [Presentation] The molecular mechanism of glaucomatous optic neuropathy: learning from a mouse model of axonal damage-induced RGC death

    • Author(s)
      中澤徹
    • Organizer
      韓国老化学会(AACL)
    • Place of Presentation
      ソウル 韓国
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 緑内障、神経保護治療からのアプローチ

    • Author(s)
      中澤徹
    • Organizer
      愛媛県眼科フォーラム
    • Place of Presentation
      松山
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • [Presentation] 緑内障における役者たち、細胞レベルの考察

    • Author(s)
      中澤徹
    • Organizer
      Ophthalmic Seminar in 多治見
    • Place of Presentation
      多治見
    • Invited
    • Data Source
      KAKENHI-PROJECT-24659756
  • 1.  Nishiguchi Koji (30447825)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 5 results
  • 2.  藤田 幸輔 (80708115)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 1 results
  • 3.  MAEDA Naoyuki (00273623)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  TANO Yasuo (80093433)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  YAMATO Masayuki (40267117)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  YOKOKURA Syunji (30400378)
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  • 28.  志賀 由己浩 (10623415)
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  • 37.  Bito Haruhiko
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  • 38.  ITOH Takehiko
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  • 39.  TAKANO Jiro
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  • 40.  TAKAHASHI Masao
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  • 41.  TAGUCHI Keiko
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  • 42.  HAYASHI Ryuhei
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  • 45.  布施 昇男
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  • 46.  福地 健郎
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  • 47.  阿部 春樹
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  • 48.  花岡 健二郎
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  • 49.  寺井 琢也
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  • 50.  小松 徹
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  • 53.  前田 理
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  • 58.  浅野 竜太郎
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  • 59.  津田 聡
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  • 60.  阿部 俊明
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  • 61.  梶 弘和
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  • 62.  永井 展裕
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