Otsu Makoto 大津真

… Alternative Names

OTSU Makoto 大津真

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Researcher Number	30361330
Other IDs
External Links
Affiliation (Current)	2025: 北里大学, 医療衛生学部, 教授
Affiliation (based on the past Project Information) *help	2012 – 2020: 東京大学, 医科学研究所, 准教授 2018: 東京大学医科学研究所, 幹細胞研究センター幹細胞プロセシング分野, 准教授 2011 – 2012: 東京大学, 医科学研究所, 特任准教授 2007 – 2010: 東京大学, 医科学研究所, 助教 2006: 東京大学, 医科学研究所, 助手 2004 – 2005: 筑波大学, 大学院・人間総合科学研究科, 講師
Review Section/Research Field	Principal Investigator Pediatrics / Experimental pathology / General medical chemistry / Hematology Except Principal Investigator Embryonic/Neonatal medicine / Pediatrics / Hematology / Collagenous pathology/Allergology / Basic Section 52050:Embryonic medicine and pediatrics-related / Medium-sized Section 58:Society medicine, nursing, and related fields … More / Biofunction/Bioprocess / Surgical dentistry / Experimental pathology / Biological Sciences Less
Keywords	Principal Investigator 造血幹細胞 / CXCL12 / CXCR4 / レトロウイルスベクター / ゲノム編集 / 人工多能性幹細胞 / 生体分子 / 免疫学 / 先天性免疫不全症 / 遺伝子発現調節 … More / ウイルスベクター / 遺伝子治療 / 同種造血細胞移植 / 移植片対宿主病 / 移植 / WHIM syndrome / retroviral vector / graft failure / hematopietic stem cell transplantation / WHIM / レトロウイルベクター / 骨髄移植 / 血液幹細胞 / WHIM症候群 / 生着不全 / 造血幹細胞移植 / プローブ / シグナル / リン酸化 / シグナル応答性プローブ / シグナル伝達 / 細胞老化 / 発現調節 / レンチウイルスベクター … More Except Principal Investigator 造血幹細胞 / iPS細胞 / 臨床 / 免疫学 / プログラム細胞死 / NETosis / 好中球 / 全身性エリテマトーデス / 遺伝・先天性異常学 / 小児血液学 / 造血幹細胞移植 / 慢性肉芽腫症 / 冬眠 / 遺伝子 / 内科 / 移植・再生医療 / 臍帯血 / 臍帯血移植の生着改善 / 造血幹細胞増幅 / 血小板回復 / 好中球回復 / 早期血球回復 / 幹細胞増幅 / 複数臍帯血移植 / 生着改善 / Neomorph / ヘテロマー干渉阻害 / 腫瘍発生 / 転写調節 / リンパ球分化 / 原発性免疫不全症 / Ikarosファミリー分子 / 機能的疾患 / 機能性疾患 / 死因究明 / 法医学 / 法医解剖 / 突然死 / SCN5A / STXBP1 / forensic autopsy / Sudden unexpected death / Postmortem iPS / 血中循環ガン細胞の単離 / 固定化細胞の光回収技術 / バイオテクノロジー / マイクロ・ナノデバイス / 受容体刺激による細胞動態解析 / 受容体の細胞内動態シミュレーション / 受容体の細胞内動態解析 / 光選択的一細胞回収 / 光選択的一細胞固定化 / 高密度一細胞アレイ / 好中球NETosis / ミトコンドリア / Apoptosis / 制御性細胞死 / 創薬スクリーニング / 創薬 / ゲノム編集 / 疾患特異的iPS細胞 / 線維性骨異形成症 / 遺伝・先天異常学 / 先天異常学 / 活性酸素 / 自己抗原提示 / NADPH酵素複合体 / 好中球Netosis / siRNA / p40phox / 好中球活性酸素 / ES細胞 / 胎児医学 / 白血病 / 先天性骨髄不全症候群 / 造血前駆細胞 / 間葉系幹細胞 / ヒト胎生期造血 / ヒトES細胞 / 細胞内アダプター蛋白 / 骨髄造血幹前駆細胞移植 / Lnk遺伝子 / 遺伝子治療モデル / 遺伝子導入ウイルス / プラム色素マーカー遺伝子 / 移植前処置軽減 / 幹細胞増殖能制御 / Lnk 蛋白 / 遺伝子導入 / 骨髄キメリズム / Lnk 遺伝子変異体 / 遺伝子治療 / smad signaling / 冬眠機構 / TGFβ / 脂質ラフト / FOXO転写因子 / 骨髄ニッチ / 白血病幹細胞 / GFAP陽性細胞 / 非髄鞘シュワン細胞 / 骨髄微小環境 / CD34陽性細胞 / リピッドラフト / ニッチシグナル / TGF-β / FOXO / ニッチ / リッピドラフト / VSV-G / 骨髄移植 / 胚性幹細胞 / レトロウイルスベクター / EGFP / huKo / 蛍光色素蛋白質 / 発生・分化 / 脳・神経 / 再生医学 / ウイルス Less

Establishment of induced pluripotent stem cells utilizing postmortem tissue derived following sudden death
- Principal Investigator
  
  Yamamoto Takuma
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Hyogo Medical University
Study on regulation of lymphocyte development by IKZF family proteins and on molecular pathogenesis of disorders caused by a mutation in IKZF family molecules.
- Principal Investigator
  
  Morio Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52050:Embryonic medicine and pediatrics-related
- Research Institution
  Tokyo Medical and Dental University
NETs including oxidative mitochondria DNA might make worse the autoimmune-inflammation in CGD
- Principal Investigator
  
  Takeuchi Emiko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kitasato University
Studies necessary to establish ideal HSC gene therapy for Wiskott Aldrich SyndromePrincipal Investigator
- Principal Investigator
  
  大津真
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Development of hematopoietic stem cell products by using multiple cord blood units
- Principal Investigator
  
  Ishida Takashi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kitasato University
Immune suppressive function of allogeneic hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  Otsu Makoto
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Experimental pathology
- Research Institution
  The University of Tokyo
Investigation of pathogenesis of leukemia in Down syndrome patients using human ES and iPS cells
- Principal Investigator
  
  MOCHIZUKI SHINJI
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  The University of Tokyo
Elucidation of fibrous dysplasia pathogenesis using disease-specific iPS cells and application to drug discovery
- Principal Investigator
  
  HOSHI Kazuto
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Surgical dentistry
- Research Institution
  The University of Tokyo
Development and its applications of a versatile system for single cell array, imaging analysis and selective cell collection
- Principal Investigator
  
  Nagamune Teruyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  The University of Tokyo
iPS細胞由来造血幹細胞を用いた動物細胞非依存的な小児血液腫瘍疾患の治療法の開発
- Principal Investigator
  
  海老原康博
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
The possibility that suppression of NETosis contributes to improvement of SLE
- Principal Investigator
  
  Takeuchi Yasuo
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Kitasato University
Analysis of occurrence of leukemia from congenital bone marrow failure syndrome and establishment of its treatment using human iPS cells
- Principal Investigator
  
  EBIHARA Yasuhiro
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  The University of Tokyo
Development and establishment of the treatment of complications in Down syndrome patients using human ES and iPS cells
- Principal Investigator
  
  MOCHIZUKI Shinji
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Molecular analysis of fetal hematopoiesis using culture system with ES cells
- Principal Investigator
  
  EBIHARA Yasuhiro
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  The University of Tokyo
A new method to sub-fractionate hematopoietic stem cells based on signal response characteristicsPrincipal Investigator
- Principal Investigator
  
  OTSU MAKOTO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
Investigation into the molecular mechanisms for the occurrence of leukemia using iPS cells derived from congenital bone marrow failure syndrome and establishment of the methods to prevent its occurrence
- Principal Investigator
  
  TSUJI Kohichiro
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pediatrics
- Research Institution
  The University of Tokyo
Analysis of human fetal hematopoiesis using human ES cells
- Principal Investigator
  
  TSUJI Kohichiro
- Project Period (FY)
  2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Embryonic/Neonatal medicine
- Research Institution
  The University of Tokyo
Human gene therapy model by induction of stable bone marrow chimerim with regulation of proliferative ability of hematopoietic stem cell
- Principal Investigator
  
  TAKEUCHI Yasuo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kitasato University
  The University of Tokyo
Elucidation of the mechanisms underlying maintenance of hematopoietic stem cell hibernation
- Principal Investigator
  
  NAKAUCHI Hiromitsu
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
In vivo Regulation of the Cell Fates Utilizing a Novel Inducible System of Protein ExpressionPrincipal Investigator
- Principal Investigator
  
  OTSU Makoto
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
Identification of niche signal prescribing hibernation of hematopoietic stem cell
- Principal Investigator
  
  NAKAUCHI Hiromitsu
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo
マルチカラーレトロウイルスベクターを用いた個体形成時の複数遺伝子競合的機能解析法
- Principal Investigator
  
  小野寺雅史
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Tsukuba
Basic Research of hematopoietic stem cell transplantation utilizing CXCR4 gene transferPrincipal Investigator
- Principal Investigator
  
  OTSU Makoto
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  University of Tsukuba

[Book] Annual Review 血液 20162016
- Author(s)
  編集／高久史麿他、著者／大津真他
- Total Pages
  236
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-15K15402
[Book] 小児内科　夢の万能細胞iPS細胞の臨床応用への道―遺伝病を中心に. –特集：ここまで治せるようになった先天代謝異常症2013
- Author(s)
  大津真
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-24659489
[Book] 遺伝子治療—特集;知っておきたい最新の免疫不全症分類—診断から治療まで2013
- Author(s)
  大津真
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24659127
[Book] 小児科診療　遺伝子治療. -特集：知っておきたい最新の免疫不全症分類―診断から治療まで2013
- Author(s)
  大津真
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24659489
[Book] 小児科診療:遺伝子治療.-特集:知っておきたい最新の免疫不全症分類?診断から治療まで2013
- Author(s)
  大津真
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24659489
[Book] 遺伝子治療. -特集：知っておきたい最新の免疫不全症分類―診断から治療まで2013
- Author(s)
  大津　真
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-24659127
[Book] -造血器腫瘍学-基礎と臨床の最新研究動向-ES/iPS細胞技術と造血幹細胞移植2012
- Author(s)
  大津真
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-24659489
[Book] ES/iPS細胞技術と造血幹細胞移植;造血器腫瘍学—基礎と臨床の最新研究動向2012
- Author(s)
  大津真
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-24659127
[Book] 日本臨床　ES/iPS細胞技術と造血幹細胞移植. –造血器腫瘍学―基礎と臨床の最新研究動向-2012
- Author(s)
  大津真
- Publisher
  日本臨床社
- Data Source
  KAKENHI-PROJECT-24659489
[Book] 夢の万能細胞iPS細胞の臨床応用への道―遺伝病を中心に. –特集：ここまで治せるようになった先天代謝異常症2012
- Author(s)
  大津　真
- Publisher
  小児内科
- Data Source
  KAKENHI-PROJECT-24659127
[Book] 夢の万能細胞iPS細胞の臨床応用への道—遺伝病を中心に;特集:ここまで治せるようになった先天代謝異常症小児内科2012
- Author(s)
  大津真
- Data Source
  KAKENHI-PROJECT-24659127
[Book] ES/iPS細胞技術と造血幹細胞移植. –造血器腫瘍学―基礎と臨床の最新研究動向-2012
- Author(s)
  大津　真
- Publisher
  日本臨床
- Data Source
  KAKENHI-PROJECT-24659127
[Book] 小児内科:夢の万能細胞iPS細胞の臨床応用への道?遺伝病を中心に.〓特集:ここまで治せるようになった先天代謝異常症2012
- Author(s)
  大津真
- Publisher
  東京医学社
- Data Source
  KAKENHI-PROJECT-24659489
[Journal Article] Generation of three induced pluripotent stem cell lines from postmortem tissue derived following sudden death of a young patient with STXBP1 mutation2019
- Author(s)
  Yamamoto T, Otsu M, Okumura T, Horie Y, Ueno Y, Taniguchi H, Ohtaka M, Nakanishi M, Abe Y, Murase T, Umehara T, Ikematsu K
- Journal Title
  
  Stem Cell Res
  
  Volume: 39 Pages: 101485-101485
- DOI
  10.1016/j.scr.2019.101485
- NAID
  120006987680
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19712, KAKENHI-PROJECT-17K19600
[Journal Article] 疾患モデルへのiPS細胞の活用2018
- Author(s)
  大津　真
- Journal Title
  
  血液フロンティア
  
  Volume: 28 Pages: 333-336
- Data Source
  KAKENHI-PROJECT-17H04225
[Journal Article] 免疫・代謝・血液疾患　原発性免疫不全症　造血幹細胞を標的とするSCID、WAS、CGDの遺伝子治療2018
- Author(s)
  大津　真
- Journal Title
  
  医学のあゆみ
  
  Volume: 265 Pages: 387-392
- Data Source
  KAKENHI-PROJECT-17H04225
[Journal Article] Dissection of Signaling Events Downstream of the c-Mpl Receptor in Murine Hematopoietic Stem Cells Via Motif-Engineered Chimeric Receptors2018
- Author(s)
  Saka Koichiro、Lai Chen-Yi、Nojima Masanori、Kawahara Masahiro、Otsu Makoto、Nakauchi Hiromitsu、Nagamune Teruyuki
- Journal Title
  
  Stem Cell Rev. Rep.
  
  Volume: 14 Issue: 1 Pages: 101-109
- DOI
  10.1007/s12015-017-9768-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19007, KAKENHI-PROJECT-15H02319, KAKENHI-PROJECT-16H02661
[Journal Article] Curative haploidentical BMT in a murine model of X-linked chronic granulomatous disease.2015
- Author(s)
  Takeuchi Y, Takeuchi E, Ishida T, Onodera M, Nakauchi H, Ohtsu M.
- Journal Title
  
  Int J Hematol
  
  Volume: 102(1) Issue: 1 Pages: 111-120
- DOI
  10.1007/s12185-015-1799-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591469, KAKENHI-PROJECT-15K15402
[Journal Article] Reactive Oxygen Species in hematopoietic stem cells affect culture outcomes under inflammatory conditions2015
- Author(s)
  Takashi Ishida, Satoshi Yamazaki, Hiromitsu Nakauchi, Masaaki Higashihara, Makoto Otsu
- Journal Title
  
  Open Journal of Hematology
  
  Volume: 6 Pages: 7-7
- DOI
  10.13055/ojhmt_6_1_7.150907
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15109
[Journal Article] <b>Hyaline cartilage formation and tumorigenesis of implanted tissues derived from human induced pluripotent stem </b><b>cells </b>2015
- Author(s)
  Saito T, Yano F, Mori D, Kawata M, Hoshi K, Takato T, Masaki H, Otsu M, Eto K, Nakauchi H, Chung UI, Tanaka S
- Journal Title
  
  Biomed. Res.
  
  Volume: 36 Issue: 3 Pages: 179-186
- DOI
  10.2220/biomedres.36.179
- NAID
  130005083858
- ISSN
  0388-6107, 1880-313X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10461, KAKENHI-PROJECT-15K10462, KAKENHI-PROJECT-15K11306, KAKENHI-PROJECT-26462285, KAKENHI-PROJECT-26463085, KAKENHI-PROJECT-15K15535, KAKENHI-PROJECT-15K15536, KAKENHI-PROJECT-15K15402, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-26293330, KAKENHI-PROJECT-25713052
[Journal Article] Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation.2014
- Author(s)
  Lai CY, Yamazaki S, Okabe M, Suzuki S, Maeyama Y, Iimura Y, Onodera M, Kakuta S, Iwakura Y, Nojima M, Otsu M, Nakauchi H.
- Journal Title
  
  Stem Cells.
  
  Volume: - Issue: 7 Pages: 1929-42
- DOI
  10.1002/stem.1670
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24500488, KAKENHI-PROJECT-24659127
[Journal Article] Generation of transgenic mouse line expressing Kusabira Orange throughout body, including erythrocytes, by random segregation of provirus method2013
- Author(s)
  Hamanaka S, Ooehara J, Morita Y, Ema H, Takahashi S, Miyawaki A, Otsu M, Yamaguchi T, Onodera M, Nakauchi H
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: i435(4) Issue: 4 Pages: 586-91
- DOI
  10.1016/j.bbrc.2013.05.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21220009, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23500490, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Immortalization of Erythroblasts by c-MYC and BCL-XL Enables Large-Scale Erythrocyte Production from Human Pluripotent Stem Cells.2013
- Author(s)
  Hirose, S., N. Takayama, S. Nakamura, K. Nagasawa, K. Ochi, S. Hirata, S. Yamazaki, T. Yamaguchi, M. Otsu, S. Sano, N. Takahashi, A. Sawaguchi, M. Ito, T. Kato, H. Nakauchi, and K. Eto.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 1 Issue: 6 Pages: 499-508
- DOI
  10.1016/j.stemcr.2013.10.010
- NAID
  120005350227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220007, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Generation of engraftable hematopoietic stem cells from induced pluripotent stem cells by way of teratoma formation.2013
- Author(s)
  Suzuki N, Yamazaki S, Yamaguchi T, Okabe M, Masaki H, Takaki S, Otsu M, Nakauchi H.
- Journal Title
  
  Mol Ther.
  
  Volume: 21 Issue: 7 Pages: 1424-31
- DOI
  10.1038/mt.2013.71
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-25293097, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Profiling of MicroRNA in Human and Mouse ES and iPS Cells Reveals Overlapping but Distinct MicroRNA Expression Patterns.2013
- Author(s)
  Razak SR, Ueno K, Takayama N, Nariai N, Nagasaki M, Saito R, Koso H, Lai CY, Murakami M, Tsuji K, Michiue T, Nakauchi H, Otsu M, Watanabe S.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 9 Pages: e73532-e73532
- DOI
  10.1371/journal.pone.0073532
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24791840, KAKENHI-PUBLICLY-25118708, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] CAMT-iPS Cells Exhibiting Defective MPL Signaling Dysregulate Megakaryopoiesis and Erythropoiesis.2013
- Author(s)
  Shinji Hirata, Naoya Takayama,Ryoko Jono-Ohnishi, Hiroshi Endo, Sou Nakamura, Takeaki Dohda, Masanori Nishi, Yuhei Hamazaki, Ei-ichi Ishii, Shin Kaneko, Makoto Otsu, Hiromitsu Nakauchi, Shinji Kunishima, and Koji Eto.
- Journal Title
  
  J Clin Invest.
  
  Volume: 123 Issue: 9 Pages: 3802-14
- DOI
  10.1172/jci64721
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23591413, KAKENHI-PROJECT-23591429, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Generation of Col2a1-EGFP iPS cells for monitoring chondrogenic differentiation2013
- Author(s)
  Saito T, Yano F, Mori D, Ohba S, Hojo H, Otsu M, Eto K, Nakauchi H, Tanaka S, Chung UI, Kawaguchi H
- Journal Title
  
  PLoS One
  
  Volume: 16;8(9) Issue: 9 Pages: e74137-e74137
- DOI
  10.1371/journal.pone.0074137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22689052, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23390358, KAKENHI-PROJECT-23390459, KAKENHI-PROJECT-23689065, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24592253, KAKENHI-PROJECT-24659665, KAKENHI-PROJECT-25253087, KAKENHI-PROJECT-25293316, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25670634, KAKENHI-PROJECT-25670851, KAKENHI-PROJECT-25713052
[Journal Article] Recurrent mutations in multiple components of the cohesin complex in myeloid neoplasms.2013
- Author(s)
  Kon A, Yoshida K
- Journal Title
  
  Nature Genet.
  
  Volume: 45 Issue: 10 Pages: 1232-1237
- DOI
  10.1038/ng.2731
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PLANNED-22134003, KAKENHI-PLANNED-22134006, KAKENHI-PROJECT-22221009, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-25290065, KAKENHI-PROJECT-25461408, KAKENHI-PROJECT-25670446, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PROJECT-25730173, KAKENHI-PROJECT-25860521
[Journal Article] ACTN1 Mutations Cause Congenital Macrothrombocytopenia2013
- Author(s)
  國島伸治、吉田健一
- Journal Title
  
  Am J Hum Genet
  
  Volume: 92 Issue: 3 Pages: 431-438
- DOI
  10.1016/j.ajhg.2013.01.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04216, KAKENHI-PROJECT-23249052, KAKENHI-PROJECT-23591429, KAKENHI-PROJECT-24390242, KAKENHI-PROJECT-24390262, KAKENHI-PROJECT-24590703, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659458, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-24791054, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PLANNED-22134006
[Journal Article] Adipose natural regulatory B cells negatively control adipose tissue inflammation2013
- Author(s)
  Nishimura S, Manabe I, Takaki S, Nagaskai M, Ostu M, Yamashita H, Sugita J, Yoshimura K, Eto K, Komuro I, Kadowaki T, Nagai R
- Journal Title
  
  Cell Metabolism
  
  Volume: 18 Issue: 5 Pages: 759-766
- DOI
  10.1016/j.cmet.2013.09.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591298, KAKENHI-PUBLICLY-24117703, KAKENHI-PROJECT-25293097, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Profiling of microRNA in human and mouse ES and iPS cells reveals overlapping but distinct microRNA expression patterns.2013
- Author(s)
  Razak SR, Ueno K, Takayama N, Nariai N, Nagasaki M, Saito R, Koso H, Lai CY, Murakami M, Tsuji K, Michiue T, Nakauchi H, Otsu M, Watanabe S.
- Journal Title
  
  PLoS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659127
[Journal Article] Top-down motif engineering of a cytokine receptor for directing ex vivo expansion of hematopoietic stem cells.2013
- Author(s)
  Saka K, Kawahara M, Teng J, Otsu M, Nakauchi H, Nagamune T.
- Journal Title
  
  J Biotechnol.
  
  Volume: 168 Issue: 4 Pages: 659-65
- DOI
  10.1016/j.jbiotec.2013.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24360337, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489
[Journal Article] Stem cell therapy: an exercise in patience and prudence.2012
- Author(s)
  Lin HT, Otsu M, Nakauchi H.
- Journal Title
  
  Philos Trans R Soc Lond B Biol Sci
  
  Volume: 5 Issue: 1609 Pages: 20110334-20110334
- DOI
  10.1098/rstb.2011.0334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659489, KAKENHI-PROJECT-25670471, KAKENHI-PROJECT-25670489, KAKENHI-PLANNED-23106004
[Journal Article] Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia2012
- Author(s)
  Keiki Kumano
- Journal Title
  
  BLOOD
  
  Volume: 119 Issue: 26 Pages: 6234-6242
- DOI
  10.1182/blood-2011-07-367441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591026, KAKENHI-PROJECT-23591369, KAKENHI-PROJECT-23650622, KAKENHI-PROJECT-23790775, KAKENHI-PROJECT-23791154, KAKENHI-PROJECT-24221011, KAKENHI-PROJECT-24249055, KAKENHI-PROJECT-24249056, KAKENHI-PROJECT-24300160, KAKENHI-PROJECT-24659127, KAKENHI-PROJECT-24659457, KAKENHI-PROJECT-24659489, KAKENHI-PLANNED-23106004, KAKENHI-PUBLICLY-23112504, KAKENHI-PUBLICLY-23130503
[Journal Article] Development of Sendai virus vectors and their potential applications in gene therapy and regenerative medicine2012
- Author(s)
  Nakanishi M, Otsu M
- Journal Title
  
  Curr Gene Ther.
  
  Volume: 12 Pages: 410-416
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659127
[Journal Article] Heterozygous ITGA2B R995W mutation inducing constitutive activation of the {alpha}IIb{beta}3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia2011
- Author(s)
  Kunishima S, Kashiwagi H, Otsu M, Takayama N, Eto K, Onodera M, Miyajima Y, Takamatsu Y, Suzumiya J, Matsubara K, Tomiyama Y, Saito H
- Journal Title
  
  Blood
  
  Volume: 117 Issue: 20 Pages: 5479-5484
- DOI
  10.1182/blood-2010-12-323691
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21300160, KAKENHI-PROJECT-21390321, KAKENHI-PROJECT-21591231, KAKENHI-PROJECT-21591242, KAKENHI-PLANNED-23106004, KAKENHI-PROJECT-23591429, KAKENHI-PROJECT-23659514, KAKENHI-PROJECT-23659533
[Journal Article] Heterozygous ITGA2B R995W mutation inducing constitutive activation of the alphaIIbbeta3 receptor affects proplatelet formation and causes congenital macrothrombocytopenia2011
- Author(s)
  Kunishima S, Kashiwagi H, Otsu M, Takayama N, Eto K, Onodera M, Miyajima Y, Takamatsu Y, Suzumiya J, Matsubara K, Tomiyama Y, Saito H
- Journal Title
  
  Blood
  
  Volume: 117 Pages: 5479-5484
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Frequent pathway mutations of splicing machinery in myelodysplasia2011
- Author(s)
  Yoshida K, Sanada M, Shiraishi Y, Nowak D, Nagata Y, Yamamoto R, Sato Y, Sato-Otsubo A, Kon A, Nagasaki M, Chalkidis G, Suzuki Y, Shiosaka M, Kawahata R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Ishiyama K, Mori H, Nolte F, Hofmann WK, Miyawaki S, Sugano S, Haferlach C, Koeffler HP, Shih LY, Haferlach T, Chiba S, Nakauchi H, Miyano S, Ogawa S
- Journal Title
  
  Nature
  
  Volume: 478 Pages: 64-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease2011
- Author(s)
  Yokoi T, Kobayashi H, Shimada Y, Eto Y, Ishige N, Kitagawa T, Otsu M, Nakauchi H, Ida H, Ohashi T
- Journal Title
  
  J Gene Med
  
  Volume: 13 Pages: 262-268
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Growth promotion of genetically modified hematopoietic progenitors using an antibody/c-Mpl chimera2011
- Author(s)
  Kawahara M, Chen J, Sogo T, Teng J, Otsu M, Onodera M, Nakauchi H, Ueda H, Nagamune T
- Journal Title
  
  Cytokine
  
  Volume: 55 Pages: 402-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Intracellular estrogen receptor-binding fragment-associated antigen 9 exerts in vivo tumor-promoting effects via its coiled-coil region2011
- Author(s)
  Maeyama Y, Otsu M, Kubo S, Yamano T, Iimura Y, Onodera M, Kondo S, Sakiyama Y, Ariga T
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 41-49
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Intracellular estrogen receptor-binding fragment-associated antigen 9 exerts in vivo tumor-promoting effects via its coiled-coil region2011
- Author(s)
  Maeyama, Y., Otsu, M., Kubo, S.
- Journal Title
  
  Int J Oncol
  
  Volume: 39 Pages: 41-49
- DOI
  10.3892/ijo.2011.1026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659533
[Journal Article] Frequent pathway mutations of splicing machinery in myelodysplasia2011
- Author(s)
  Yoshida K, Sanada M, Shiraishi Y, Nowak D, Nagata Y, Yamamoto R, Sato Y, Sato-Otsubo A, Kon A, Nagasaki M, Chalkidis G, Suzuki Y, Shiosaka M, Kawahata R, Yamaguchi T, Otsu M, Obara N, Sakata-Yanagimoto M, Ishiyama K, Mori H, Nolte F, Hofmann WK, Miyawaki
- Journal Title
  
  Nature
  
  Volume: 478 Pages: 64-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells2010
- Author(s)
  Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, Eto K
- Journal Title
  
  J Exp Med
  
  Volume: 207 Pages: 2817-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.2010
- Author(s)
  Ogawa S, Sanada M, Shin LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP.
- Journal Title
  
  Cell Cycle. 9(6)(In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms2010
- Author(s)
  Ogawa S, Sanada M, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP
- Journal Title
  
  Cell Cycle
  
  Volume: 9 Pages: 1051-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Reduction of N-glycolylneuraminic acid in human induced pluripotent stem cells generated or cultured under feeder-and serum-free defined conditions2010
- Author(s)
  Hayashi Y, Chan T, Warashina M, Fukuda M, Ariizumi T, Okabayashi K, Takayama N, Otsu M, Eto K, Furue MK, Michiue T, Ohnuma K, Nakauchi H, Asashima M
- Journal Title
  
  PLoS One
  
  Volume: 5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Reprogramming adult hematopoietic cells.2010
- Author(s)
  Kaneko S, Otsu M, Nakauchi H.
- Journal Title
  
  Curr Opin Hematol
  
  Volume: 17 Pages: 271-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Deregulated intracellular signaling by mutated c-CBL in myeloid neoplasms.2010
- Author(s)
  Ogawa S, Shih LY, Suzuki T, Otsu M, Nakauchi H, KoefflerHP, Sanada M.
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 3825-3831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Reprogramming adult hematopoietic cells2010
- Author(s)
  Kaneko S, Otsu M, Nakauchi H
- Journal Title
  
  Opin Hematol
  
  Volume: 17 Pages: 271-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells2010
- Author(s)
  Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, Eto K
- Journal Title
  
  J Exp Med
  
  Volume: 207 Pages: 2817-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Reprogramming adult hematopoietic cells2010
- Author(s)
  Kaneko S, Otsu M, Nakauchi H
- Journal Title
  
  Curr Opin Hematol
  
  Volume: 17 Pages: 271-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Koeffler HP, Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms2010
- Author(s)
  Ogawa S, Sanada M, Shih LY, Suzuki T, Otsu M, Nakauchi H
- Journal Title
  
  Cell Cycle
  
  Volume: 9 Pages: 1051-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Deregulated intracellular signaling by mutated c-CBL in myeloid neoplasms2010
- Author(s)
  Ogawa S, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP, Sanada M
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 3825-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Gain-of-function c-CBL mutations associated with uniparental disomy of 11q in myeloid neoplasms.2010
- Author(s)
  Ogawa S, Sanada M, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP.
- Journal Title
  
  Cell Cycle
  
  Volume: 9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Reprogramming adult hematopoietic cells.2010
- Author(s)
  Kaneko S, Otsu M, Nakauc hi H
- Journal Title
  
  Curr Opin Hematol
  
  Volume: 17 Pages: 271-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Deregulated intracellular signaling by mutated c-CBL in myeloid neoplasms2010
- Author(s)
  Ogawa S, Shih LY, Suzuki T, Otsu M, Nakauchi H, Koeffler HP, Sanada M
- Journal Title
  
  Clin Cancer Res
  
  Volume: 16 Pages: 3825-31
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera.2009
- Author(s)
  Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T.
- Journal Title
  
  Cytokine 46
  
  Pages: 127-36
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.2009
- Author(s)
  Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S.
- Journal Title
  
  Nature 460
  
  Pages: 904-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.2009
- Author(s)
  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.
- Journal Title
  
  Stem Cells 27
  
  Pages: 1120-1129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera2009
- Author(s)
  Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T
- Journal Title
  
  Cytokine
  
  Volume: 46 Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Definitive proof for direct reprogramming of hematopoietic cells to pluripotency2009
- Author(s)
  Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H
- Journal Title
  
  Blood
  
  Volume: 114 Pages: 1764-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms2009
- Author(s)
  Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
- Journal Title
  
  Nature
  
  Volume: 460 Pages: 904-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms2009
- Author(s)
  Sanada M, Suzuki T, Shih LY, Otsu M, Kato M, Yamazaki S, Tamura A, Honda H, Sakata-Yanagimoto M, Kumano K, Oda H, Yamagata T, Takita J, Gotoh N, Nakazaki K, Kawamata N, Onodera M, Nobuyoshi M, Hayashi Y, Harada H, Kurokawa M, Chiba S, Mori H, Ozawa K, Omine M, Hirai H, Nakauchi H, Koeffler HP, Ogawa S
- Journal Title
  
  Nature
  
  Volume: 460 Pages: 904-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells2009
- Author(s)
  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H
- Journal Title
  
  Stem Cells
  
  Volume: 27 Pages: 1120-1129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591231
[Journal Article] Definitive proof for direct reprogramming of hematopoietic cells to pluripotency.2009
- Author(s)
  Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H.
- Journal Title
  
  Blood 114
  
  Pages: 1764-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] The actin polymerization regulatorWAVE2 is required for early bone marrowrepopulation by hematopoietic stem cells2009
- Author(s)
  Ogaeri T, Eto K, Otsu M, Ema H, NakauchiH
- Journal Title
  
  Stem Cells 27
  
  Pages: 1120-1129
- Data Source
  KAKENHI-PROJECT-19209036
[Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells2009
- Author(s)
  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H
- Journal Title
  
  Stem Cells
  
  Volume: 27 Pages: 1120-1129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Definitive proof for direct reprogramming of hematopoietic cells to pluripotency2009
- Author(s)
  Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H
- Journal Title
  
  Blood
  
  Volume: 114 Pages: 1764-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249059
[Journal Article] Stable Transgene Expression in Mice Generated from Retrovirally Transduced Embryonic Stem Cells2007
- Author(s)
  Hamanaka S, Nabekura T, Otsu M, Yoshida H, Nagata M, Usui J, Takahashi S, Nagasawa T, Nakauchi H, Onodera M.
- Journal Title
  
  Mol Ther. 15
  
  Pages: 560-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209036
[Journal Article] Stable Transgene Expression in MiceGenerated from Retrovirally TransducedEmbryonic Stem2007
- Author(s)
  Hamanaka S, Nabekura T, Otsu M, YoshidaH, Nagata M, Usui J, Takahashi S,Nagasawa T, Nakauchi H, Onodera M
- Journal Title
  
  Cells. Mol Ther 15
  
  Pages: 560-5
- Data Source
  KAKENHI-PROJECT-19209036
[Journal Article] Potent vaccine therapy with dendritic cells genetically modified by the retroviral vector GCDNsap.2006
- Author(s)
  Nabekura T, Otsu M, Nagasawa T, Nakauchi H, Onodera M.
- Journal Title
  
  Molecular Therapy 13(2)
  
  Pages: 301-309
- Data Source
  KAKENHI-PROJECT-17045005
[Journal Article] Potent vaccine therapy with dendritic cells genetically modified by the gene-silencing-resistant retroviral vector GCDNsap.2006
- Author(s)
  Nabekura T, Otsu M, Nagasawa T, et al.
- Journal Title
  
  Molecular Therapy 13(2)
  
  Pages: 301-309
- Data Source
  KAKENHI-PROJECT-16390293
[Journal Article] T cell growth control using hapten-specific antibody/interleukin-2 receptor chimera.
- Author(s)
  Sogo T, Kawahara M, Ueda H, Otsu M, Onodera M, Nakauchi H, Nagamune T.
- Journal Title
  
  Cytokine. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209036
[Journal Article] Definitive proof fordirect reprogramming of hematopoieticcells to pluripotency
- Author(s)
  Okabe M, Otsu M, Ahn DH, Kobayashi T, Wakiyama Y, Morita Y, Onodera M, Eto K, Ema H, Nakauchi H
- Journal Title
  
  Blood. (in press)
- Data Source
  KAKENHI-PROJECT-19209036
[Journal Article] The actin polymerization regulator WAVE2 is required for early bone marrow repopulation by hematopoietic stem cells.
- Author(s)
  Ogaeri T, Eto K, Otsu M, Ema H, Nakauchi H.
- Journal Title
  
  Stem Cells. in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19209036
[Patent] 造血幹細胞移植用の組合せ細胞製剤および生着促進剤並びにこれらの製造方法2013
- Inventor(s)
  大津真、中内啓光、高橋聡、石田隆
- Industrial Property Rights Holder
  東京大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-213024
- Filing Date
  2013-10-10
- Data Source
  KAKENHI-PROJECT-24659127
[Patent] 誘導型多能性幹細胞の製造方法2011
- Inventor(s)
  中内啓光,大津真,高山直也,安東赫
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-06-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21249059
[Patent] 誘導型多能性幹細胞の製造方法2011
- Inventor(s)
  中内啓光, 大津真, 高山直也, 安東赫
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-06-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21249059
[Patent] 誘導型多能性幹細胞の製造方法2011
- Inventor(s)
  中内啓光,大津真,高山直也,安東赫
- Industrial Property Rights Holder
  東京大学
- Filing Date
  2011-06-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21591231
[Patent] ウイルス産生細胞2009
- Inventor(s)
  中内啓光、江藤浩之、大津真、高山直也
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-19209036
[Presentation] X連鎖性慢性肉芽腫症モデルgp91phoxknock-out mouseへの肉芽腫形成誘導とNOX2依存的細胞死の関連について．2020
- Author(s)
  竹内恵美子・竹内康雄・大津　真
- Organizer
  第48回臨床免疫学会
- Data Source
  KAKENHI-PROJECT-17K10006
[Presentation] 血液免疫難病の克服を目指す幹細胞研究2018
- Author(s)
  大津真
- Organizer
  第77回神奈川血液研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16194
[Presentation] 人工多能性幹（iPS）細胞を用いた血液免疫異常症における病態モデル研究2018
- Author(s)
  大津　真
- Organizer
  第9回関東甲越免疫不全症研究会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04225
[Presentation] 血液免疫難病における iPS 細胞を用いたモデル研究2018
- Author(s)
  大津　真
- Organizer
  第39回日本炎症・再生医学会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-17H04225
[Presentation] Reevaluation of the utility of induced pluripotent stem cells as a model for Wiskott Aldrich Syndrome2017
- Author(s)
  Honda-Ozaki F., Lin H.T., Okumra T., Lai C.Y., Otsu M
- Organizer
  第23回日本遺伝子細胞治療学会
- Data Source
  KAKENHI-PROJECT-17H04225
[Presentation] Evaluation of the Utility of Induced Pluripotent Stem Cells as a Platform for Modeling Wiskott Aldrich Syndrome2017
- Author(s)
  Honda-Ozaki F., Lin H.T., Lai C.Y., Otsu M
- Organizer
  第46回日本免疫学会
- Data Source
  KAKENHI-PROJECT-17H04225
[Presentation] 骨髄炎症下における造血幹細胞保護2015
- Author(s)
  石田隆、鈴木幸恵、Chen-Yi Lai、角田茂、岩倉洋一郎、野島正寛、竹内康雄、東原正明、中内啓光、大津真
- Organizer
  第８０回日本インターフェロン・サイトカイン学会
- Place of Presentation
  東京工業大学蔵前会館蔵前ホール（東京都目黒区）
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-15K15109
[Presentation] 骨髄炎症環境における造血幹細胞保護法の確立2015
- Author(s)
  大津真、石田隆
- Organizer
  第25回日本サイトメトリー学会
- Place of Presentation
  ソラシティーカンファレンスセンター（東京都千代田区）
- Year and Date
  2015-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-15K15109
[Presentation] Drug screening for the 8p11 myeloproliferative syndrome using patient iPS cells2013
- Author(s)
  Mai Nanya, Shohei Yamamoto, Yasuhiro Ebihara, Shinji Mochizuki, Makoto Otsu, Minoru Tozuka, Hiromitsu Nakauchi, KohichiroTsuji
- Organizer
  第75回日本血液学会
- Place of Presentation
  ロイトン札幌, 札幌
- Data Source
  KAKENHI-PROJECT-25670471
[Presentation] A Possible Therapeutic Strategy for Genetic Diseases Using Hematopoietic Stem Cells Generated from Induced Pluripotent Stem Cells2013
- Author(s)
  Makoto Otsu
- Organizer
  ESGCT and SETGyC Collaborative Congress
- Place of Presentation
  Madrid, Spain
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] Translation of Stem Cell Science from Bench to Bedside2013
- Author(s)
  Makoto Otsu
- Organizer
  International Medi-Bio Symposium of SIMS-IMSUT-WIS
- Place of Presentation
  Asan, Korea
- Invited
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] 自己骨髄由来間葉系幹細胞を用いた血友病関節症に対する治療の可能性2013
- Author(s)
  海老原康博, 望月慎史, 大津真, 竹谷英之, 辻浩一郎
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡シーホーク, 福岡
- Data Source
  KAKENHI-PROJECT-25670489
[Presentation] 自己骨髄由来間葉系幹細胞を用いた血友病関節症に対する治療の可能性2013
- Author(s)
  海老原康博、望月慎史、大津真、竹谷英之、辻浩一郎
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  福岡：ヒルトン福岡シーホーク
- Data Source
  KAKENHI-PROJECT-25670471
[Presentation] 自己骨髄由来間葉系幹細胞を用いた血友病関節症に対する治療の可能性2013
- Author(s)
  海老原康博, 望月慎史, 大津真, 竹谷英之, 辻浩一郎
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  ヒルトン福岡, 福岡
- Data Source
  KAKENHI-PROJECT-25670471
[Presentation] Translation of Stem Cell Science from Bench to Bedside2013
- Author(s)
  Makoto Otsu
- Organizer
  International Medi-Bio Symposium of SIMS-IMSUT-WIS (invited)
- Place of Presentation
  Asan, Korea
- Year and Date
  2013-11-18
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] Drug screening for the 8p11 myeloproliferative syndrome using patient iPS cells2013
- Author(s)
  Mai Nanya, Shohei Yamamoto, Yasuhiro Ebihara, Shinji Mochizuki, Makoto Otsu, Minoru Tozuka, Hiromitsu Nakauchi, Kohichiro Tsuji
- Organizer
  第75回日本血液学会
- Place of Presentation
  札幌：ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25670471
[Presentation] ELUCIDATION OF PATHOPHYSIOLOGICAL MECHANISMS IN WISKOTT ALDRICH SYNDROME USING INDUCED PLURIPOTENT STEM CELLS (iPSC)2013
- Author(s)
  Mozhgan Khalaj Amirhosseini, Makoto Otsu, Hiromitsu Nakauchi
- Organizer
  第19回日本遺伝子治療学会学術集会
- Place of Presentation
  岡山全日空ホテル
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] Pleiotropic nature of hematopoietic stem cell responses to an inflammatory niche environment (invited)2013
- Author(s)
  Makoto Otsu
- Place of Presentation
  Tokyo
- Year and Date
  2013-01-28
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] 自己骨髄由来間葉系幹細胞を用いた血友病関節症に対する治療の可能性2013
- Author(s)
  海老原康博、望月慎史、大津真、竹谷英之、辻浩一郎
- Organizer
  第55回日本小児血液・がん学会学術集会
- Place of Presentation
  福岡：ヒルトン福岡シーホーク
- Data Source
  KAKENHI-PROJECT-25670489
[Presentation] leiotropic nature of hematopoietic stem cell responses to an inflammatory niche environment2013
- Author(s)
  Makoto Otsu
- Organizer
  The 2nd Joint Global COE Symposium of the IMSUT & RCAST Global COE.The Univ of Tokyo and Chiba Univ Global COE
- Place of Presentation
  東京
- Year and Date
  2013-01-28
- Data Source
  KAKENHI-PROJECT-24659489
[Presentation] もっと知りたいiPS細胞2013
- Author(s)
  大津真
- Organizer
  第31回市民公開医療懇談会
- Place of Presentation
  東京
- Year and Date
  2013-02-27
- Data Source
  KAKENHI-PROJECT-24659489
[Presentation] Drug screening for the 8p11 myeloproliferative syndrome using patient iPS cells2013
- Author(s)
  Mai Nanya, Shohei Yamamoto, Yasuhiro Ebihara, Shinji Mochizuki, Makoto Otsu, Minoru Tozuka, Hiromitsu Nakauchi, Kohichiro Tsuji
- Organizer
  第75回日本血液学会
- Place of Presentation
  札幌：ロイトン札幌
- Data Source
  KAKENHI-PROJECT-25670489
[Presentation] ALPHARETROVIRAL VECTORS: DEMONSTRATION OF SAFE AND EFFICACIOUS GENE THERAPY USING X-CGD iPSCS.2013
- Author(s)
  Lin Huan Ting, Makoto Otsu, Hiromitsu Nakauchi
- Organizer
  第19回日本遺伝子治療学会学術集会
- Place of Presentation
  岡山全日空ホテル
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] A possible therapeutic strategy for genetic diseases using hematopoietic stem cells generated from induced pluripotent stem cells2013
- Author(s)
  Makoto Otsu
- Organizer
  ESGCT and SETGyC Collaborative Congress
- Place of Presentation
  Madrid, Spain
- Year and Date
  2013-10-26
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] Drug screening for the 8p11 myeloproliferative syndrome using patient iPS cells2013
- Author(s)
  Mai Nanya, Shohei Yamamoto, Yasuhiro Ebihara, Shinji Mochizuki, Makoto Otsu, Minoru Tozuka, Hiromitsu Nakauchi, Kohichiro Tsuji
- Organizer
  第75回日本血液学会
- Place of Presentation
  ロイトン札幌, 札幌
- Data Source
  KAKENHI-PROJECT-25670489
[Presentation] Pleiotropic nature of hematopoietic stem cell responses to an inflammatory niche environment.2013
- Author(s)
  Makoto Otsu.
- Organizer
  he 2nd Joint Global COE Symposium of the IMSUT & RCAST Global COE, The Univ of Tokyo and Chiba Univ Global COE.
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24659489
[Presentation] Myeloablationを必要としない造血幹細胞移植法の確立に向けてTowards the establishment of hematopoietic stem cell transplantation without the need for myeloablation2012
- Author(s)
  Makoto Otsu
- Organizer
  第34回日本造血細胞移植学会総会・日本再生医療学会合同シンポジウム[造血幹細胞移植の未来]
- Place of Presentation
  大阪
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Protection of hematopoietic stem cells from stress-induced functional impairment by very low-dose interleukin-1 stimulation.2012
- Author(s)
  M. Otsu et al.
- Organizer
  European Society of Gene & Cell Therapy 20th Anniversary Congress with the SFTCG
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-24659489
[Presentation] Development of experimental animal model of human gene therapy for X-CGD2012
- Author(s)
  Takeuchi Y, Amirhosseini M, Franklin L, Takeuchi E, Nakauchi H, Otsu M
- Organizer
  第38回ヨーロッパ骨髄移植会議
- Place of Presentation
  Geneva, Switzerland
- Data Source
  KAKENHI-PROJECT-22590355
[Presentation] Protection of hematopoietic stem cells from stress-induced functional impairment by very low-dose interleukin-1 stimulation2012
- Author(s)
  M. Otsu & J. Ooehara.
- Organizer
  European Society of Gene & Cell Therapy 20th Anniversary Congress with the SFTCG.
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] Towards the establishment of hematopoietic stem cell transplantation without the need for myeloablation2012
- Author(s)
  Makoto Otsu
- Organizer
  第34回日本造血細胞移植学会総会日本再生医療学会合同シンポジウム
- Place of Presentation
  Osaka, Japan(招待講演)
- Year and Date
  2012-02-24
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Protection of hematopoietic stem cells fromstress-induced functional impairment by very low-dose interleukin-1 stimulation2012
- Author(s)
  M. Otsu
- Organizer
  European Society of Gene & Cell Therapy 20th Anniversary Congress with the SFTCG
- Place of Presentation
  Paris,France
- Data Source
  KAKENHI-PROJECT-24659489
[Presentation] STEM CELL GENE THERAPY FOR PRIMARY IMMUNODEFICIENCY DISEASES : WHERE ARE WE TODAY AND WHERE SHOULD WE GO?2011
- Author(s)
  Makoto Otsu
- Organizer
  JSGT 17th Annual Meeting
- Place of Presentation
  Fukuoka, Japan(招待講演)
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Stem Cell Gene Therapy for Primary Immunodeficiency Diseases.-Where are we now and where should we go?-2011
- Author(s)
  Makoto Otsu
- Organizer
  第17回日本遺伝子治療学会シンポジウム
- Place of Presentation
  福岡
- Year and Date
  2011-07-17
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] より良い造血細胞移植を目指して:造血幹細胞における生着および骨髄再構築能の制御2011
- Author(s)
  Makoto Otsu
- Organizer
  第10回神奈川小児血液・感染症フォーラム
- Place of Presentation
  横浜
- Year and Date
  2011-02-09
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Update of Stem Cell Gene Therapy Clinical Trial for ADA-Deficiency in Japan2010
- Author(s)
  Otsu, M, et al.
- Organizer
  13th annual meeting of ASGCT
- Place of Presentation
  Washington DC, USA
- Year and Date
  2010-05-22
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Stem Cell Gene Therapy For Adenosine Deaminase-Deficiency : A Report of Six-Year Outcomes In 2 Treated Patients2010
- Author(s)
  Otsu, M, et al.
- Organizer
  16^<th> annual meeting of JSGT
- Place of Presentation
  Tochigi-ken General Culture Center
- Year and Date
  2010-07-01
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Hematopoietic Cells and Induced Pluripotent Stem Cells : Good Friends in Regenerative Medicine?2010
- Author(s)
  大津真
- Organizer
  日本再生医療学会総会
- Place of Presentation
  広島
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Update on a Japanese clinical trial of Stem Cell Gene Therapy for ADA-Deficiency2010
- Author(s)
  Otsu, M, et al.
- Organizer
  18th annual congress of the ESGCT
- Place of Presentation
  Milan, Italy
- Year and Date
  2010-10-22
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] Three-year clinical follow-up of 5 patients treated with suicide gene modified donor lymphocyte infusion therapy in Japan2009
- Author(s)
  金子新、Y.Ohkokshi、大津真、N.Nemoto、T.Nanmoku、Kazumi Suzukawa、Y.Hasegawa、H.Kojima、T.Fukushima、R.Sumazaki、小野寺雅史、Y.Harada、H.Sakamaki、M.Tsuchida、S.Kato、C.Bonini、C.Bordignon、S.Chiba、中内啓光、T.Nakasawa
- Organizer
  第15回日本遺伝子治療学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21249059
[Presentation] 先天性免疫不全症の遺伝子細胞治療2009
- Author(s)
  大津真
- Organizer
  第37回日本臨床免疫学会総会
- Place of Presentation
  東京
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21591231
[Presentation] RCCに対して同種臍帯血移植を施行した2例
- Author(s)
  海老原康博, 望月慎史, 大津真, 辻浩一郎
- Organizer
  日本小児血液・がん学会
- Place of Presentation
  岡山コンベンションセンター（岡山県岡山市）
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-26670511
[Presentation] Pleiotropic nature of hematopoietic stem cell responses to an inflammatory niche environment
- Author(s)
  Makoto Otsu
- Organizer
  The 2nd Joint Global COE Symposium of the IMSUT & RCAST Global COE
- Place of Presentation
  Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-24659127
[Presentation] RCCに対して同種臍帯血移植を施行した2例
- Author(s)
  海老原康博, 望月慎史, 大津真, 辻浩一郎
- Organizer
  日本小児血液・がん学会
- Place of Presentation
  岡山コンベンションセンター(岡山県岡山市）
- Year and Date
  2014-11-28 – 2014-11-30
- Data Source
  KAKENHI-PROJECT-26293243

1. MOCHIZUKI Shinji (90349473)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. EBIHARA Yasuhiro (40302608)

# of Collaborated Projects: 5 results

# of Collaborated Products: 6 results
3. TAKAUCHI Yasuo (60286359)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
4. NAKAUCHI Hiromitsu (40175485)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
5. TSUJI Kohichiro (50179991)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Takeuchi Emiko (00406935)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
7. TAKAHASHI Satoshi (60226834)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. LAI Chen-Yi (30739925)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. Morio Tomohiro (30239628)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Ishida Takashi (90596470)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. 小野寺雅史 (10334062)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
12. KATAYAMA Yoshiki (70284528)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. ARIGA Tadashi (60322806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. MIYAMOTO Masaki (40333611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. HOSHI Kazuto (30344451)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. Nagamune Teruyuki (20124373)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. YAMAGUCHI Satoshi (80398106)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAKAMURA Motonao (40431762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. Yamamoto Takuma (50634458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. Suzuki Takahiro (40345210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Miyazaki Koji (90261966)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 高戸毅 (90171454)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 西澤悟 (00646200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 河原正浩 (50345097)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 梅原敬弘 (60617421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
26. 池松和哉 (80332857)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
27. 西尾元 (90253260)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 三浦綾 (90814814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 奥村高志 (20449234)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
30. ETO Tomoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. ITO Ryoji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. KANEKO Shin

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. 依馬正次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
35. 江藤浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
36. 高橋武司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
37. 伊藤守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 矢野文子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 吉田健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
40. 山下尋史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Otsu Makoto 大津 真

OTSU Makoto 大津 真

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

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Studies necessary to establish ideal HSC gene therapy for Wiskott Aldrich SyndromePrincipal Investigator

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Immune suppressive function of allogeneic hematopoietic stem cellsPrincipal Investigator

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A new method to sub-fractionate hematopoietic stem cells based on signal response characteristicsPrincipal Investigator

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Otsu Makoto 大津真

OTSU Makoto 大津真

[Book] 小児内科　夢の万能細胞iPS細胞の臨床応用への道―遺伝病を中心に. –特集：ここまで治せるようになった先天代謝異常症2013