Iwasaki Ryotaro 岩崎良太郎

… Alternative Names

岩崎良太郎イワサキリョウタロウ

Ryotaro Iwasaki 岩崎良太郎

RYOTARO Iwasaki 岩崎良太郎

IWASAKI Ryoutarou 岩崎良太郎

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Researcher Number	30365390
Other IDs
Affiliation (Current)	2025: 慶應義塾大学, 医学部(信濃町), 講師(非常勤)
Affiliation (based on the past Project Information) *help	2023: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2019 – 2021: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2016 – 2017: 慶應義塾大学, 医学部(信濃町), 講師(非常勤) 2013 – 2015: 慶應義塾大学, 医学部, 講師(非常勤) 2012: 慶應義塾大学, 医学部, 助教 2009 – 2010: Keio University, 医学部, 助教
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related / Functional basic dentistry Except Principal Investigator Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 破骨細胞 / 骨代謝 / 歯科口腔外科 / 骨吸収薬関連顎骨壊死 / 炎症性サイトカイン / カップリング / TGFβ / Smad4 / 細胞融合 / 遺伝子 / 発生・分化 / 歯学 … More Except Principal Investigator … More NFκβ経路 / ERα経路 Less

下顎頭吸収性疾患のERα経路とNF-κB経路のクロストーク機構の解明
- Principal Investigator
  
  宗像花楠子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Keio University
Elucidation of bone destroying diseases and establishment of therapy by regulation of inflammatory cytokinesPrincipal Investigator
- Principal Investigator
  
  Ryotaro Iwasaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Keio University
Smad4 is required to inhibit osteoclastogenesis and maintain bone massPrincipal Investigator
- Principal Investigator
  
  Iwasaki Ryotaro
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Surgical dentistry
- Research Institution
  Keio University
To clalify the new regulator of cell-cell fusion of osteoclastsPrincipal Investigator
- Principal Investigator
  
  RYOTARO Iwasaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Keio University
To clarify the role of osteoclast fusion in bone homeostasisPrincipal Investigator
- Principal Investigator
  
  IWASAKI Ryoutarou
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Keio University

All 2021 2020 2019 2017 2016 2013 2012 2010 2009 Other

All Journal Article Presentation

[Journal Article] Tooth extraction in mice administered zoledronate increases inflammatory cytokine levels and promotes osteonecrosis of the jaw2020
- Author(s)
  Soma T, Iwasaki R, Sato Y, Kobayashi T, Nakamura S, Kaneko Y, Ito E, Okada H, Watanabe H, Miyamoto K, Matsumoto M, Nakamura M, Asoda S, Kawana H, Nakagawa T, Miyamoto T
- Journal Title
  
  J Bone Miner Metab
  
  Volume: - Issue: 3 Pages: 372-384
- DOI
  10.1007/s00774-020-01174-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09580, KAKENHI-PROJECT-19K10365, KAKENHI-PROJECT-20K09461, KAKENHI-PROJECT-18H02930, KAKENHI-PROJECT-18K09017, KAKENHI-PROJECT-19K09655
[Journal Article] TNFα promotes osteosarcoma progression by maintaining tumor cells in an undifferentiated state.2013
- Author(s)
  Mori T,Sato Y Iwasaki R et.al.,
- Journal Title
  
  Oncogene
  
  Volume: 545 Pages: 1-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24792252
[Journal Article] Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis2012
- Author(s)
  Hoshi H, Hao W, Fujita Y, Funayama A, Miyauchi Y, Hashimoto K, Miyamoto K, (他21名)
- Journal Title
  
  J. Bone Miner Res
  
  Volume: 27(9) Issue: 9 Pages: 2015-2023
- DOI
  10.1002/jbmr.1634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23300257, KAKENHI-PROJECT-23390217, KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24500882, KAKENHI-PROJECT-24570151, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24651055, KAKENHI-PROJECT-24659395, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] PDGFBB promotes PDGFRα-positive cell migration into artificial bone in vivo.2012
- Author(s)
  Yoshida S, Iwasaki R, Kawana H, Miyauchi Y, Hoshi H, Miyamoto H, Mori T, Kanagawa H et al.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 421 Issue: 4 Pages: 785-789
- DOI
  10.1016/j.bbrc.2012.04.084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] OC-STAMP and DC-STAMP cooperatively modulate cell-cell fusion to form osteoclasts and foreign body giant cells2012
- Author(s)
  Miyamoto H, et al
- Journal Title
  
  J Bone Miner Res
  
  Volume: (In press) Issue: 6 Pages: 1289-1297
- DOI
  10.1002/jbmr.1575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21689040, KAKENHI-PROJECT-23592231, KAKENHI-PROJECT-24390359, KAKENHI-PROJECT-24614014, KAKENHI-PROJECT-24791561, KAKENHI-PROJECT-24792252
[Journal Article] The Blimpl-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.2010
- Author(s)
  Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T
- Journal Title
  
  The Journal of Experimental Medicine
  
  Volume: 204 Pages: 751-762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791813
[Journal Article] The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.2010
- Author(s)
  Miyauchi Y, Ninomiya K, Miyamoto H, Sakamoto A, Iwasaki R, Hoshi H, Miyamoto K, Hao W, Yoshida S, Morioka H, Chiba K, Kato S, Tokuhisa T, Saitou M, Toyama Y, Suda T, Miyamoto T.
- Journal Title
  
  J Exp Med. 207(4)
  
  Pages: 751-762
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791813
[Journal Article] MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner.2009
- Author(s)
  Miyamoto K, Ninomiya K, Sonoda KH, Miyauchi Y, Hoshi H, Iwasaki R, Miyamoto H, Yoshida S, Sato Y, Morioka H, Chiba K, Egashira K, Suda T, Toyama Y, Miyamoto T.
- Journal Title
  
  Biochem Biophys Res Commun. 383(3)
  
  Pages: 373-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791813
[Journal Article] MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner.2009
- Author(s)
  Miyamoto K, Ninomiya K, Sonoda KH, Miyauchi Y, Hoshi H, Iwasaki R, Miyamoto H, Yoshida S, Sato Y, Morioka H, Chiba K, Egashira K, Suda T, Toyama Y, Miyamoto T.
- Journal Title
  
  Biochem Biophys Res Commun. 383
  
  Pages: 373-377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21791813
[Presentation] ゾレドロネート投与と侵襲的歯科処置は，炎症性サイトカインを上昇させ，骨吸収薬剤関連顎骨壊死を誘発する2021
- Author(s)
  相馬智也 , 森田麻友 , 岩崎良太郎 , 莇生田整治 , 河奈裕正 , 中川種昭 , 宮本健史
- Organizer
  第75回NPO法人日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10365
[Presentation] 骨吸収抑制薬関連顎骨壊死モデルにおける炎症性サイトカイン制御による抑制効果の検証2021
- Author(s)
  相馬智也 , 森田麻友 , 岩崎良太郎 , 莇生田整治 , 中川種昭 , 宮本健史
- Organizer
  第39回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10365
[Presentation] 炎症性サイトカイン制御による骨吸収抑制薬関連顎骨壊死の抑制2020
- Author(s)
  相馬智也，森田麻友，岩崎良太郎，莇生田整治，河奈裕正，中川種昭，宮本健史
- Organizer
  第38回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10365
[Presentation] 炎症性サイトカイン制御による骨吸収抑制薬関連顎骨壊死の抑制効果2020
- Author(s)
  相馬智也，森田麻友，岩崎良太郎，莇生田整治，河奈裕正，中川種昭，宮本健史
- Organizer
  第65回(公社)日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10365
[Presentation] Elevated levels of pro-inflammatory cytokines are required for anti-resorptive agent-related osteonecrosis of the Jaw development in mice2019
- Author(s)
  Tomoya Soma, Mayu Morita, Ryotaro Iwasaki, Seiji Asoda, Hiromasa Kawana, Taneaki Nakagawa,Takeshi Miyamoto
- Organizer
  ASBMR（American Society for Bone and Mineral Research）2019 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10365
[Presentation] 骨吸収抑制薬による薬剤関連顎骨壊死には炎症性サイトカインの上昇が必須である2019
- Author(s)
  相馬智也，森田麻友，岩崎良太郎，莇生田整治，河奈裕正，中川種昭，宮本健史
- Organizer
  第64回(公社)日本口腔外科学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10365
[Presentation] Smad4 in Osteoclasts reduce bone mass by inhibiting osteoclast differentiation2017
- Author(s)
  Ryotaro Iwasaki, Mayu Morita, Shigeyuki Yoshida, Taneaki Nakagawa, Takeshi Miyamoto , Hiromasa Kawana
- Organizer
  23rd International Conference on Oral and Maxillofacial Surgery
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11268
[Presentation] Osteonecrosis due to bacterial infection following bisphosphonate treatment2017
- Author(s)
  森田麻友、岩崎良太郎、相馬智也、中川種昭、河奈裕正
- Organizer
  第６２回日本口腔外科学会総会
- Data Source
  KAKENHI-PROJECT-15K11268
[Presentation] 破骨細胞に発現するSmad4は破骨細胞の分化抑制および骨量維持に必須である2016
- Author(s)
  森田麻友, 岩崎良太郎, 河奈裕正, 中川種昭, 宮本健史
- Organizer
  第34回日本骨代謝学会学術集会/第3回アジア太平洋骨代謝学会議
- Place of Presentation
  大阪国際会議場　(日本、大阪府）
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-15K11268
[Presentation] Smad4 in Osteoclasts reduce bone mass by inhibiting osteoclast differentiation2016
- Author(s)
  Mayu Morita, Ryotaro Iwasaki, Hiromasa Kawana, Taneaki Nakagawa, and Takeshi Miyamoto
- Organizer
  The 38th The American Society for Bone and Mineral Research
- Place of Presentation
  Atlanta U.S.A
- Year and Date
  2016-09-16
- Data Source
  KAKENHI-PROJECT-15K11268
[Presentation] TNFα and IL-1 are both essential cytokines for the tumorigenesis of mouse osteosarcoma cell line AX.2013
- Author(s)
  Iwasaki R,Miyamoto T et.al.,
- Organizer
  21th International conference on pral and maxillofacial surgery
- Place of Presentation
  Barcelona,Spain
- Data Source
  KAKENHI-PROJECT-24792252
[Presentation] TNFαおよびIL-1はマウス骨肉腫細胞株AXの腫瘍形成に必須である2013
- Author(s)
  岩崎良太郎、宮本健史、森田麻友、臼田慎、宮下英高、莇生田整治、中川種昭、河奈裕正
- Organizer
  第５８回日本口腔外科学会総会
- Place of Presentation
  福岡国際会議場、福岡県
- Data Source
  KAKENHI-PROJECT-24792252
[Presentation] PDGF-BB promotes PDGFRα-positive cell migration into artificial bone in vivo2012
- Author(s)
  Yoshida S, Iwasaki R, Kawana H, Nakagawa T, Miyamoto T
- Organizer
  2012 ASBMR annual meeting
- Place of Presentation
  Minneapolis convention center at Minneapolis, Minnesota, USA
- Data Source
  KAKENHI-PROJECT-24792252
[Presentation] PDGFR alpha-positive cells were migrated into artificial bone by PDGFBB in vivo.2012
- Author(s)
  R. Iwasaki, S. Yoshida, T. Miyamoto, T. Nakagawa, H. Kawana
- Organizer
  10th Asian Congress on Oral and Maxillofacial surgery
- Place of Presentation
  Discovery Kartika Plaza Hotel Bali-Indonesia
- Data Source
  KAKENHI-PROJECT-24792252
[Presentation] PDGF-BB promotes PDGFRα-positive cell migration into artificial bone in vivo2012
- Author(s)
  Yoshida S, Iwasaki R, Kawana H, Nakagawa T, Miyamoto T
- Organizer
  ASBMR Topical meetings bone and skeletal muscle
- Place of Presentation
  ASBMR Topical meetings bone and skeletal muscle
- Data Source
  KAKENHI-PROJECT-24792252
[Presentation] 破骨細胞の細胞融合は骨量と骨芽細胞の活性を制御する2010
- Author(s)
  岩崎良太郎、宮本健史、小山慶介、深谷千絵、中川種昭
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2010-06-11
- Data Source
  KAKENHI-PROJECT-21791813
[Presentation] DC-STAMP regulates bone homeostasis through cell-cell fusion of osteoclasts2009
- Author(s)
  R.Iwasaki, H.Kawana, S,Asoda, Y.Toyam T.Nakagawa, T.Suda, T.Miyamoto
- Organizer
  The 26^<th> Naito Bonference on osteobiology
- Place of Presentation
  兵庫県淡路島
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21791813
[Presentation] 破骨細胞の細胞融合は骨量と骨芽細胞の活性を制御する2009
- Author(s)
  岩崎良太郎、宮本健史、吉田重之、莇生田整治、中川種昭、河奈裕正
- Organizer
  第54回口腔外科学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21791813
[Presentation] 破骨細胞の細胞融合は骨量と骨芽細胞の活性を制御する2009
- Author(s)
  岩崎良太郎, 宮本健史, 吉田重之, 莇生田整治, 中川種昭, 河奈裕正
- Organizer
  第54回日本口腔外科学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-10-10
- Data Source
  KAKENHI-PROJECT-21791813
[Presentation] DC-STAMP regulates bone homeostasis through cell-cell fusion of osteoclasts2009
- Author(s)
  R.Iwasaki, H.Kawana, S.Asoda, Y.Toyam T.Nakagawa, T.Suda, T.Miyamoto
- Organizer
  The 26th Naito Bonference on osteobiology
- Place of Presentation
  兵庫県淡路島
- Year and Date
  2009-11-06
- Data Source
  KAKENHI-PROJECT-21791813
[Presentation] 破骨細胞に発現するSmad4は箱津市安房の分化抑制から骨量を減少する
- Author(s)
  森田麻友、岩崎良太郎、宮本健史、河奈裕正、中川種昭
- Organizer
  第５９回日本口腔外科学会総会
- Place of Presentation
  幕張メッセ国際会議場、東京　千葉
- Year and Date
  2014-10-17 – 2014-10-19
- Data Source
  KAKENHI-PROJECT-24792252
[Presentation] Both Cytokines, TNFα and IL-1 are Essential for the Tumorigenesis of Mouse Osteosarcoma.
- Author(s)
  Ryotaro Iwasaki,Takeshi Miyamoto ,Mayu Morita ,Tomoaki Mori ,Taneaki Nakagawa,Hiromsa Kawana
- Organizer
  96th AAOMS Annual Meeting, Scientific Sessions and Exhibition
- Place of Presentation
  Hawaii Convention Center、USA
- Year and Date
  2014-09-08 – 2014-09-13
- Data Source
  KAKENHI-PROJECT-24792252

1. 宗像花楠子 (20896378)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 宮下英高 (20445290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. MIYAUCHI Yoshiteru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. MIYAMOTO Takeshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 佐藤結子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Iwasaki Ryotaro 岩崎 良太郎

岩崎 良太郎 イワサキ リョウタロウ

Ryotaro Iwasaki 岩崎 良太郎

RYOTARO Iwasaki 岩崎 良太郎

IWASAKI Ryoutarou 岩崎 良太郎

Research Projects

Research Products

Co-Researchers

下顎頭吸収性疾患のERα経路とNF-κB経路のクロストーク機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of bone destroying diseases and establishment of therapy by regulation of inflammatory cytokinesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Smad4 is required to inhibit osteoclastogenesis and maintain bone massPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To clalify the new regulator of cell-cell fusion of osteoclastsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To clarify the role of osteoclast fusion in bone homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Tooth extraction in mice administered zoledronate increases inflammatory cytokine levels and promotes osteonecrosis of the jaw2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TNFα promotes osteosarcoma progression by maintaining tumor cells in an undifferentiated state.2013

Author(s)

Journal Title

Data Source

[Journal Article] Aldehyde-stress resulting from Aldh2 mutation promotes osteoporosis due to impaired osteoblastogenesis2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PDGFBB promotes PDGFRα-positive cell migration into artificial bone in vivo.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] OC-STAMP and DC-STAMP cooperatively modulate cell-cell fusion to form osteoclasts and foreign body giant cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Blimpl-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.2010

Author(s)

Journal Title

Data Source

[Journal Article] The Blimp1-Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis.2010

Author(s)

Journal Title

Data Source

[Journal Article] MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner.2009

Author(s)

Journal Title

Data Source

[Journal Article] MCP-1 expressed by osteoclasts stimulates osteoclastogenesis in an autocrine/paracrine manner.2009

Author(s)

Journal Title

Data Source

[Presentation] ゾレドロネート投与と侵襲的歯科処置は，炎症性サイトカインを上昇させ，骨吸収薬剤関連顎骨壊死を誘発する2021

Author(s)

Iwasaki Ryotaro 岩崎良太郎

岩崎良太郎イワサキリョウタロウ

Ryotaro Iwasaki 岩崎良太郎

RYOTARO Iwasaki 岩崎良太郎

IWASAKI Ryoutarou 岩崎良太郎