Seike Masahiro 清家正博

… Alternative Names

SEIKE Masahiro 清家正博

清家正博セイケマサヒロ

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Researcher Number	30366687
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 大学院教授
Affiliation (based on the past Project Information) *help	2017 – 2022: 日本医科大学, 医学部, 教授 2011 – 2016: 日本医科大学, 医学部, 准教授 2008 – 2010: 日本医科大学, 医学部, 講師 2005: 日本医大, 医学部, 助手 2004: 日本医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related Except Principal Investigator Respiratory organ internal medicine / Basic Section 53030:Respiratory medicine-related
Keywords	Principal Investigator 肺癌 / マイクロRNA / トランスレーショナルリサーチ / エクソソーム / 免疫チェックポイント阻害薬 / 非コードRNA / がん免疫療法 / 薬剤反応性 / ドライバー遺伝子 / 分子標的薬 … More / 薬剤耐性 / 低分子RNA / 血清 / 薬剤感受性 / PTEN / Akt / 抗体アレイ / 2D-DIGE / cDNAアレイ / ゲフィチニブ … More Except Principal Investigator 肺癌 / 間質性肺炎 / VEGFR / EGFR / 抗体アレイ / イメージング / 免疫療法 / 遺伝子解析 / microbiome / microRNA / エクソゾーム / miRNA / II型肺胞上皮 / エクソソーム / マイクロRNA / 気管支肺胞洗浄液 / 臨床呼吸器学 / 癌 / 術後再発 / Ⅰ期非小細胞肺癌 / 遺伝子シグネチャー / 血管浸潤 / 早期肺癌再発予測 / 4遺伝子シグネチャー / 肺腺がん / 再発予測 / 肺カルチノイド / 融合遺伝子 / 遺伝子変異 / 肺神経内分泌腫瘍 / 次世代シーケンサー / 網羅的タンパク質解析 / 原発性肺癌 / 特発性間質性肺炎 / プロテオーム解析 / バイオマーカー / 化学療法 / 急性増悪 / p53 / driver gene 変異 / 転写因子 / アポトーシス / cancer stem cell / セカンドアタック / ドライバー遺伝子 / シグナル情報 / 網羅的解析 / 感受性予測 / 分子標的治療 / 肺癌薬剤感受性プロテオーム / "D-DIGE / バイオイメージング / 分子標的薬 / 薬物療法 / 2D-DIGE / プロテオーム / 薬剤感受性 Less

Identification of the respiratory microbiome associated with lung cancer by comprehensive genomic profiling
- Principal Investigator
  
  Miyanaga Akihiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
Serum-derived exosomal microRNA predicts the response to immune checkpoint inhibitors cancer in lung cancer patientsPrincipal Investigator
- Principal Investigator
  
  SEIKE MASAHIRO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Nippon Medical School
4 gene signature will predict the recurrence for stage I lung carcinomas.
- Principal Investigator
  
  Noro Rintaro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Long non cording RNA associated with drug resistance in lung cancer with driver mutationPrincipal Investigator
- Principal Investigator
  
  SEIKE MASAHIRO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Identification of the genomic landscape in pulmonary neuroendocrine tumor
- Principal Investigator
  
  MIYANAGA AKIHIKO
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
MicroRNA and exosome in interstitial pneumonia
- Principal Investigator
  
  Kunugi Shinobu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Finishing blow therapy in lung cancer with driver gene mutation
- Principal Investigator
  
  Gemma Akihiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Research for biomarker of chemotherapy related-acute exacerbation of idiopathic interstitial pneumonias
- Principal Investigator
  
  Minegishi Yuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Identification of serum exosomal microRNA in lung cancerPrincipal Investigator
- Principal Investigator
  
  SEIKE MASAHIRO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Development of molecular predictive model for molecular targeted therapy in lung cancer using pathway analysis
- Principal Investigator
  
  GEMMA Akihiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Prediction of drug sensitivity and development of a therapeutic strategy by microRNAs in lung cancerPrincipal Investigator
- Principal Investigator
  
  SEIKE Masahiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
Identification of chemosensitivity predictive factors in lung cancer cells and chemosensitivity prediction by image
- Principal Investigator
  
  GENMA Akihiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School
肺癌治療におけるゲフィチニブ感受性予測法の開発Principal Investigator
- Principal Investigator
  
  清家正博
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Nippon Medical School

[Book] 抗癌剤の効果予測因子としてのバイオマーカー2010
- Author(s)
  清家正博、弦間昭彦
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-21591008
[Journal Article] The respiratory microbiome associated with chronic obstructive pulmonary disease comorbidity in non-small cell lung cancer2022
- Author(s)
  Shimizu M, Miyanaga A, Seike M, Matsuda K, Matsumoto M, Noro R, Kubota K, Gemma A
- Journal Title
  
  Thorac Cancer
  
  Volume: 13 Issue: 13 Pages: 1940-1947
- DOI
  10.1111/1759-7714.14463
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08552
[Journal Article] Interstitial lung disease associated with nanoparticle albumin-bound paclitaxel treatment in patients with lung cancer.2019
- Author(s)
  Kashiwada T, Saito Y, Terasaki Y, Hisakane K, Takeuchi S, Sugano T, Miyanaga A, Noro R, Minegishi Y, Seike M, Kubota K, Gemma A.
- Journal Title
  
  Jpn J Clin Oncol.
  
  Volume: 1;49(2): Issue: 2 Pages: 165-173
- DOI
  10.1093/jjco/hyy180
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09630, KAKENHI-PROJECT-17KK0177, KAKENHI-PROJECT-16K09561
[Journal Article] Tenascin XB Is a Novel Diagnostic Marker for Malignant Mesothelioma2019
- Author(s)
  NAKAYAMA KOJI、SEIKE MASAHIRO、NORO RINTARO、TAKEUCHI SUSUMU、MATSUDA KUNIKO、KUNUGI SHINOBU、KUBOTA KAORU、GEMMA AKIHIKO
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 2 Pages: 627-633
- DOI
  10.21873/anticanres.13156
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17KK0177, KAKENHI-PROJECT-16K09561
[Journal Article] Prognostic Significance of NSCLC and Response to EGFR-TKIs of EGFR-Mutated NSCLC Based on PD-L1 Expression.2018
- Author(s)
  Kobayashi K, Seike M, Zou F, Noro R, Chiba M, Ishikawa A, Kunugi S, Kubota K, Gemma A.
- Journal Title
  
  Anticancer Res.
  
  Volume: 38
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09561
[Journal Article] Ankyrin Repeat Domain 1 Overexpression is Associated with Common Resistance to Afatinib and Osimertinib in EGFR-mutant Lung Cancer2018
- Author(s)
  Takahashi Akiko、Seike Masahiro、Chiba Mika、Takahashi Satoshi、Nakamichi Shinji、Matsumoto Masaru、Takeuchi Susumu、Minegishi Yuji、Noro Rintaro、Kunugi Shinobu、Kubota Kaoru、Gemma Akihiko
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 14896-14896
- DOI
  10.1038/s41598-018-33190-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0177, KAKENHI-PROJECT-16K09561
[Journal Article] AXL and GAS6 co-expression in lung adenocarcinoma as a prognostic classifier.2017
- Author(s)
  Seike M, Kim CH, Zou F, Noro R, Chiba M, Ishikawa A, Κunugi S, Kubota K, Gemma A
- Journal Title
  
  Oncol Rep. 2017
  
  Volume: 37 Issue: 6 Pages: 3261-3269
- DOI
  10.3892/or.2017.5594
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09561
[Journal Article] A Two-Gene Prognostic Classifier for Early-Stage Lung Squamous Cell Carcinoma in Multiple Large-Scale and Geographically Diverse Cohorts.2017
- Author(s)
  Noro R, Ishigame T, Walsh N, Shiraishi K, Robles AI, Ryan BM, Schetter AJ, Bowman ED, Welsh JA, Seike M, Gemma A, Skaug V, Mollerup S, Haugen A, Yokota J, Kohno T, Harris CC.
- Journal Title
  
  J Thorac Oncol
  
  Volume: 12(1) Issue: 1 Pages: 65-76
- DOI
  10.1016/j.jtho.2016.08.141
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09561
[Journal Article] Prognostic significance of ABCB1 in stage I lung adenocarcinoma.2017
- Author(s)
  Zou F, Seike M, Noro R, Kunugi S, Kubota K, Gemma A.
- Journal Title
  
  Oncol Lett.
  
  Volume: 14 Issue: 1 Pages: 313-321
- DOI
  10.3892/ol.2017.6145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09561
[Journal Article] Identification of haptoglobin peptide as a novel serum biomarker for lung squamous cell carcinoma by serum proteome and peptidome profiling.2016
- Author(s)
  Okano T, Seike M, Kuribayashi H, Soeno C, Ishii T, Kida K, Gemma A.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48(3) Issue: 3 Pages: 945-52
- DOI
  10.3892/ijo.2016.3330
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] Cisplatin-induced apoptosis in non-small-cell lung cancer cells is dependent on Bax- and Bak-induction pathway and synergistically activated by BH3-mimetic ABT-263 in p53 wild-type and mutant cells.2016
- Author(s)
  Matsumoto M, Nakajima W, Seike M, Gemma A, Tanaka N.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 473(2) Issue: 2 Pages: 490-6
- DOI
  10.1016/j.bbrc.2016.03.053
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461172, KAKENHI-PROJECT-26670164, KAKENHI-PROJECT-16K11161
[Journal Article] miR-200/ZEB axis regulates sensitivity to nintedanib in non-small cell lung cancer cells.2016
- Author(s)
  Nishijima N, Seike M, Soeno C, Chiba M, Miyanaga A, Noro R, Sugano T, Matsumoto M, Kubota K, Gemma A.
- Journal Title
  
  Int J Oncol.
  
  Volume: 48(3) Issue: 3 Pages: 937-44
- DOI
  10.3892/ijo.2016.3331
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461172, KAKENHI-PROJECT-16K09561
[Journal Article] Interstitial lung disease associated with amrubicin chemotherapy in patients with lung cancer: a single institutional study.2016
- Author(s)
  Miura Y1, Saito Y2, Atsumi K1, Takeuchi S1, Miyanaga A1, Mizutani H, Minegishi Y, Noro R, Seike M, Kunugi S, Kubota K, Gemma A.
- Journal Title
  
  Jpn J Clin Oncol. 2016 Jul;46(7):674-80.
  
  Volume: 46(7) Issue: 7 Pages: 674-680
- DOI
  10.1093/jjco/hyw043
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26461204, KAKENHI-PROJECT-16K09561
[Journal Article] Inhibition of ABCB1 Overcomes Cancer Stem Cell-like Properties and Acquired Resistance to MET Inhibitors in Non-Small Cell Lung Cancer.2015
- Author(s)
  Sugano T, Seike M, Noro R, Soeno C, Chiba M, Zou F, Nakamichi S, Nishijima N, Matsumoto M, Miyanaga A, Kubota K, Gemma A.
- Journal Title
  
  Mol Cancer Ther.
  
  Volume: 14(11) Issue: 11 Pages: 2433-40
- DOI
  10.1158/1535-7163.mct-15-0050
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] Effective Crizotinib schedule for an elderly patient with ALK rearranged non-small-cell lung cancer: a case report.2015
- Author(s)
  Fukuizumi A, Miyanaga A, Seike M, Kato Y, Nakamichi S, Chubachi K, Matsumoto M, Noro R, Minegishi Y, Kunugi S, Kubota K, Gemma A
- Journal Title
  
  BMC Res Notes.
  
  Volume: 8 Issue: 1 Pages: 165-165
- DOI
  10.1186/s13104-015-1126-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461204, KAKENHI-PROJECT-25461172
[Journal Article] MET FISH-positive status predicts short progression-free survival and overall survival after gefitinib treatment in lung adenocarcinoma with EGFR mutation.2015
- Author(s)
  Noro R, Seike M, Zou F, Soeno C, Matsuda K, Sugano T, Nishijima N, Matsumoto M, Kitamura K, Kosaihira S, Minegishi Y, Yoshimura A, Kubota K, Gemma A.
- Journal Title
  
  BMC Cancer
  
  Volume: 15(1) Pages: 31-31
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] Prognostic significance of PIK3CA and SOX2 in Asian patients with lung squamous cell carcinoma.2015
- Author(s)
  Iijima Y, Seike M, Noro R, Ibi T, Takeuchi S, Mikami I, Koizumi K, Usuda J, Gemma A.
- Journal Title
  
  Int J Oncol.
  
  Volume: 46(2) Issue: 2 Pages: 505-12
- DOI
  10.3892/ijo.2014.2742
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer.2015
- Author(s)
  Matsumoto M, Seike M, Noro R, Soeno C, Sugano T, Takeuchi S, Miyanaga A, Kitamura K, Kubota K, Gemma A.
- Journal Title
  
  BMC Cancer
  
  Volume: 15(1) Pages: 241-241
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] MiR-379/411 cluster regulates IL-18 and contributes to drug resistance in malignant pleural mesothelioma.2015
- Author(s)
  Yamamoto K, Seike M, Takeuchi S, Soeno C, Miyanaga A, Noro R, Minegishi Y, Kubota K, Gemma A.
- Journal Title
  
  Oncol Rep.
  
  Volume: 32(6) Issue: 6 Pages: 2365-72
- DOI
  10.3892/or.2014.3481
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] Clinical features, anti-cancer treatments and outcomes of lung cancer patients with combined pulmonary fibrosis and emphysema.2014
- Author(s)
  Minegishi Y, Kokuho N, Miura Y, Matsumoto M, Miyanaga A, Noro R, Saito Y, Seike M, Kubota K, Azuma A, Kida K, Gemma A.
- Journal Title
  
  Lung Cancer
  
  Volume: 85(2) Issue: 2 Pages: 258-63
- DOI
  10.1016/j.lungcan.2014.05.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] Nestin regulates proliferation, migration, invasion and stemness of lung adenocarcinoma2014
- Author(s)
  Narita K, Matsuda Y, Seike M, Naito Z, Gemma A, Ishiwata T
- Journal Title
  
  Int J Oncol
  
  Volume: 44(4) Issue: 4 Pages: 1118-30
- DOI
  10.3892/ijo.2014.2278
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590477, KAKENHI-PROJECT-25461172, KAKENHI-PROJECT-25462127
[Journal Article] 呼吸器のバイオマーカーとしてのmicroRNA2014
- Author(s)
  清家　正博
- Journal Title
  
  THE LUNG perspective
  
  Volume: 22(4) Pages: 413-417
- Data Source
  KAKENHI-PROJECT-24591179
[Journal Article] Significance of osteopontin in the sensitivity of malignant pleural mesothelioma to pemetrexed.2014
- Author(s)
  Takeuchi S, Seike M, Noro R, Soeno C, Sugano T, Zou F, Uesaka H, Nishijima N, Matsumoto M, Minegishi Y, Kubota K, Gemma A.
- Journal Title
  
  Int J Oncol.
  
  Volume: 44(6) Issue: 6 Pages: 1886-94
- DOI
  10.3892/ijo.2014.2370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461172
[Journal Article] MiR-134/487b/655 cluster regulates TGF-β-induced　epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung　adenocarcinoma cells2014
- Author(s)
  Kitakura K, Seike M, Okano T et.al
- Journal Title
  
  Molecular Cancer Therapeutic
  
  Volume: 13(2) Issue: 2 Pages: 444-453
- DOI
  10.1158/1535-7163.mct-13-0448
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591179, KAKENHI-PROJECT-25461172
[Journal Article] Activity of EGFR-tyrosine kinase and ALK inhibitors for EML4-ALK-rearranged non-small-cell lung cancer harbored coexisting EGFR mutation.2013
- Author(s)
  Miyanaga A, et al. 18人中14番目
- Journal Title
  
  BMC Cancer
  
  Volume: 13 Issue: 1 Pages: 262-262
- DOI
  10.1186/1471-2407-13-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25250020, KAKENHI-PROJECT-25461172
[Journal Article] MiR-23a regulates TGF-β-induced epithelial-mesenchymal transition by targeting E-cadherin in lung cancer cells2012
- Author(s)
  Mengru C, Seike M, Soeno C, Mizutani H, Kitamura K, Minegishi Y, Noro R, Yoshimura A, Gemma A
- Journal Title
  
  Int J Oncol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591008
[Journal Article] Enzastaurin has anti-tumour effects in lung cancers with overexpressed JAK pathway molecules2012
- Author(s)
  Shimokawa T, Seike M, Soeno C, Uesaka H, Miyanaga A, Mizutani H, Kitamura K, Minegishi Y, Noro R, Okano T, Yoshimura A, Gemma A
- Journal Title
  
  Br J Cancer
  
  Volume: 106(5) Issue: 5 Pages: 867-75
- DOI
  10.1038/bjc.2012.7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591006, KAKENHI-PROJECT-21591008, KAKENHI-PROJECT-22590874
[Journal Article] The safety and efficacy of weekly paclitaxel in combination with carboplatin for advanced non-small cell lung cancer with idiopathic interstitial pneumonias2011
- Author(s)
  Minegishi Y, Sudoh J, Kuribayasi H, Mizutani H, Seike M, Azuma A, Yoshimura A, Kudoh S, Gemma A
- Journal Title
  
  Lung Cancer
  
  Volume: 71(1) Issue: 1 Pages: 70-4
- DOI
  10.1016/j.lungcan.2010.04.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591006
[Journal Article] The feasibility study of Carboplatin plus Etoposide for advanced small cell lung cancer with idiopathic interstitial pneumonias2011
- Author(s)
  Minegishi Y, Kuribayashi H, Kitamura K, Mizutani H, Kosaihira S, Okano T, Seike M, Azuma A, Yoshimura A, Kudoh S, Gemma A
- Journal Title
  
  J Thorac Oncol
  
  Volume: 6(4) Issue: 4 Pages: 801-7
- DOI
  10.1097/jto.0b013e3182103d3c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591006, KAKENHI-PROJECT-22590874
[Journal Article] Histone deacetylase inhibitor enhances sensitivity of non-small-cell lung cancer cells to 5-FU/S-1 via down-regulation of thymidylate synthase expression and up-regulation of p21(waf1/cip1) expression2010
- Author(s)
  Noro R, Miyanaga A, Minegishi Y, Okano T, Seike M, Soeno C, Kataoka K, Matsuda KYoshimura A, Gemma A
- Journal Title
  
  Cancer Sci
  
  Volume: 101(6) Issue: 6 Pages: 1424-30
- DOI
  10.1111/j.1349-7006.2010.01559.x
- NAID
  10026593453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591006
[Journal Article] HSP27 modulates epithelial to mesenchymal transition of lung cancer cells in a Smad-independent manner2010
- Author(s)
  Mizutani H, Okano T, Minegishi Y, Matsuda K, Sudoh J, Kitamura K, Noro R, Soeno C, Yoshimura A, Seike M, Gemma A
- Journal Title
  
  Oncology Letter
  
  Volume: 1 Issue: 6 Pages: 1011-1016
- DOI
  10.3892/ol.2010.190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591008
[Journal Article] MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers2009
- Author(s)
  Seike M, Goto A, Okano T, Bowman ED, Schetter AJ, Horikawa I, Mathe EA, Jen J, Yang P, Sugimura H, Gemma A, Kudoh S, Croce CM, Harris CC.
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106(29) Issue: 29 Pages: 12085-90
- DOI
  10.1073/pnas.0905234106
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591006
[Journal Article] MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers.2009
- Author(s)
  Seike M
- Journal Title
  
  Proc Natl Acad Sci USA. 106(29)
  
  Pages: 12085-12090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591006
[Journal Article] Antitumor activity of histone deacetylase inhibitors in non-small cell lung cancer cells : development of a molecular predictive model.2008
- Author(s)
  Miyanaga A, Gemma A, Noro R, Kataoka K, Matsuda K, Nara M, Okano T, Seike M, Yoshimura A, Kawakami A, Uesaka H, Nakae H, Kudoh S.
- Journal Title
  
  Mol Cancer Ther.
  
  Pages: 1923-30
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590919
[Journal Article] In vitro simulation study of individualized chemotherapy in lung cancer.2007
- Author(s)
  Li C, Gemma A, Minegishi Y, Matsuda K, Seike Y, Noro R, Shionoya A, Kawakami A, Ogawa N, Kudoh S
- Journal Title
  
  J Nippon Med Sch. 74(3)
  
  Pages: 217-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590919
[Journal Article] PTEN inactivation in lung cancercells and the effect of its recovery on treatment with epidermal growth factor receptor tyrosine kinase inhibitors.2007
- Author(s)
  Noro R, Gemma A, Miyanaga A, Kosaihira S, Minegishi Y, Nara M, Kokubo Y, Seike M, Kataoka K, Matsuda K, Okano T, Yoshimura A, Kudoh S.
- Journal Title
  
  Int J Oncol. 31(5)
  
  Pages: 1157-63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590919
[Journal Article] Use of a cytokine gene expression signature in lung adenocarcinoma and the surrounding tissue as a prognostic classifier.2007
- Author(s)
  Seike M, Yanaihara N, Bowman ED, Zanetti KA, Budhu A, Kumamoto K, Mechanic LE, Matsumoto S, Yokota J, Shibata T, Sugimura H, Gemma A, Kudoh S, Wang XW, Harris CC.
- Journal Title
  
  J Natl Cancer Inst 99(16)
  
  Pages: 1257-69
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590919
[Presentation] 血清エクソームmiR-125aはNSCLC患者におけるICIの治療効果を予測する2021
- Author(s)
  久金翔、清家正博　他
- Organizer
  第61回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08615
[Presentation] 血清エクソソームmiR-125a-3pはNSCLC患者におけるICIの治療効果を予測する2021
- Author(s)
  久金翔、清家正博　他
- Organizer
  第61回日本呼吸器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08615
[Presentation] デジタルPCRによる肺癌に関与するマイクロバイオームの探索2020
- Author(s)
  清水理光, 宮永晃彦, 野呂林太郎, 久保田馨, 清家正博, 弦間昭彦
- Organizer
  日本肺癌学会
- Data Source
  KAKENHI-PROJECT-20K08552
[Presentation] Genomic profiling of lung cancer associated with idiopathic pulmonary fibrosis2018
- Author(s)
  Noro R, Miyanaga A, Fukuizumi A, Seike M, Kubota K, Gemma A
- Organizer
  AACR
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09561
[Presentation] ...Abstract 3209: Polo-like kinase 1 as a new molecular target for small cell lung carcinoma2017
- Author(s)
  Noro R, Seike M, Zou F, Gemma A
- Organizer
  AACR; Cancer Res 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09561
[Presentation] 1.Ⅰ期肺腺癌再発予測システムの構築―術後化学療法とACTN4遺伝子増幅2017
- Author(s)
  野呂林太郎三浦奈美本田一文白石英晶藤原豊大江裕一郎石井源一郎蔦幸治淺村尚生山田哲司清家正博久保田馨弦間昭彦
- Organizer
  第55回日本癌治療学会
- Data Source
  KAKENHI-PROJECT-16K09561
[Presentation] Ｏｍｉｃｓと感受性予測研究2014
- Author(s)
  清家　正博
- Organizer
  第52回日本癌治療学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2014-08-28
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] 肺癌におけるmicroRNA異常の解明と新規治療法の開発に向けた研究2014
- Author(s)
  清家　正博
- Organizer
  第55回日本肺癌学会学術集会
- Place of Presentation
  京都
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] 肺癌におけるmicroRNA異常の解明と新規治療法の開発に向けた研究2014
- Author(s)
  清家正博
- Organizer
  第５５回日本肺癌学会（学会賞受賞講演）
- Place of Presentation
  京都
- Year and Date
  2014-11-15
- Invited
- Data Source
  KAKENHI-PROJECT-25461172
[Presentation] EMT による耐性2014
- Author(s)
  清家正博
- Organizer
  第５４回日本呼吸器学会（招請講演）
- Place of Presentation
  大阪
- Year and Date
  2014-04-16
- Invited
- Data Source
  KAKENHI-PROJECT-25461172
[Presentation] 肺癌の発生と薬剤感受性に関与するmiR-21の意義2011
- Author(s)
  清家正博
- Organizer
  第20回日本癌病態治療研究会
- Place of Presentation
  東京
- Year and Date
  2011-06-17
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] miR-23aはSmad依存的にTGFβ誘導上皮間葉移行(EMT)を制御する2011
- Author(s)
  清家正博
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] 肺癌の個別化治療とトランスレーショナルリサーチの現状2011
- Author(s)
  清家正博
- Organizer
  日本医科大学オーダーメイド医療講演会
- Place of Presentation
  東京
- Year and Date
  2011-09-12
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] miR-23aはSmad依存的にTGFβ誘導上皮間葉移行(EMT)を制御する2011
- Author(s)
  清家正博、野呂林太郎、峯岸裕司、添野千絵、吉村明修、弦間昭彦
- Organizer
  第70回日本癌学会総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] 肺がん細胞の薬剤感受性に関与するマイクロRNA発現プロファイル2010
- Author(s)
  清家正博
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21591006
[Presentation] 肺がん細胞の薬剤感受性に関与するマイクロRNA発現プロファイル2010
- Author(s)
  清家正博、岡野哲也、添野千絵、峯岸裕司、野呂林太郎、吉村明修、弦間昭彦
- Organizer
  第69回日本癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] Gene expression profiles in lung cancer cells cooperated with drug sensitivity to PKC inhibitor enzastaurin2010
- Author(s)
  清家正博, 他
- Organizer
  AACR 101st Annual Meeting 2010
- Place of Presentation
  米国ワシントンDC
- Year and Date
  2010-04-19
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] Gene expression profiles in lung cancer cells cooperated with drug sensitivity to PKC inhibitor enzastaurin2010
- Author(s)
  Seike M, Smimokawa T, Soeno C, Okano T, Minegishi Y, Yoshimura A and Gemma A
- Organizer
  101st AACR Annual Meeting
- Place of Presentation
  Washington DC
- Year and Date
  2010-04-06
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] 肺癌のEGFR-TKI感受性に関するmicroRNA研究2010
- Author(s)
  清家正博
- Organizer
  第5回肺癌分子病態研究会
- Place of Presentation
  東京
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] 非喫煙者肺癌およびEGFR-TKI感受性に関与するmiR-21の役割2009
- Author(s)
  清家正博、岡野哲也、吉村明修、弦間昭彦
- Organizer
  第50回日本肺癌学会総会
- Year and Date
  2009-11-13
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] 肺癌の診断および治療戦略におけるmiRNA研究2009
- Author(s)
  清家正博
- Organizer
  私立大学戦略的研究基盤形成支援事業シンポジウ
- Place of Presentation
  東京
- Year and Date
  2009-11-07
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] 非喫煙者肺癌およびEGFR-TKI感受性に関与するmiR-21の役割2009
- Author(s)
  清家正博、岡野哲也、吉村明修、弦間昭彦
- Organizer
  第68回日本癌学会総会
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] MicroRNA expression profiles modulate the drug sensitivity of lung cancer cells2009
- Author(s)
  Seike M, Noro R, Soeno C, Shimokawa T, Miyanaga A, Yoshimura A and Gemma A
- Organizer
  100th AACR Annual Meeting
- Place of Presentation
  Denver
- Year and Date
  2009-04-19
- Data Source
  KAKENHI-PROJECT-21591008
[Presentation] MicroRNAによる新たな肺癌治療戦略
- Author(s)
  清家　正博
- Organizer
  戦略的研究基盤形成支援事業シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] 低分子RNAとがん研究
- Author(s)
  清家正博
- Organizer
  第５３回日本呼吸器学会学術総会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] 低分子RNAとがん研究　ー miRNAと肺癌ー
- Author(s)
  清家　正博
- Organizer
  第53回日本呼吸器学会学術集会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] 肺がん治療の最前線　肺癌治療感受性予測研究の展開
- Author(s)
  清家正博
- Organizer
  第５１回日本癌治療学会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-25461172
[Presentation] 肺癌におけるmiRNAを用いた新規治療法の探索
- Author(s)
  清家正博
- Organizer
  私立大学戦略的研究基盤形成支援事業シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] シンポジウム　最近の分子生物学の進歩とがん研究　低分子RNAとがん研究
- Author(s)
  清家正博
- Organizer
  第５３回日本呼吸器学会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25461172
[Presentation] 肺癌治療感受性予測研究の展望
- Author(s)
  清家　正博
- Organizer
  第18回日本癌治療学会学術集会
- Place of Presentation
  京都
- Invited
- Data Source
  KAKENHI-PROJECT-24591179
[Presentation] MicroRNA and Lung Cancer
- Author(s)
  清家　正博
- Organizer
  第51回 APSR Annual Meeting
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-24591179

1. GENMA Akihiko (20234651)

# of Collaborated Projects: 6 results

# of Collaborated Products: 28 results
2. Noro Rintaro (50366738)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
3. MINEGISHI Yuji (80386234)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
4. MIYANAGA AKIHIKO (00591281)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. KUDOH Shoji (40256912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
6. OKANO Tetsuya (00339376)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. TANAKA Nobuyuki (80222115)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. YAMADA Tesshi (30221659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Kunugi Shinobu (30350036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. MIYAKE KOUICHI (90267211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. NAGASAKA SHINYA (00573239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TERASAKI MIKA (50372785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. ISHIKAWA ARIMI (40598992)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KUWAHARA NAOMI (00599011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 寺崎泰弘 (50332870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. HAMADA Michiaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. Curtis Harris

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. NAITO Zenya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. ISHIWATA Toshiyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. MATSUDA Yoko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Seike Masahiro 清家 正博

SEIKE Masahiro 清家 正博

清家 正博 セイケ マサヒロ

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Serum-derived exosomal microRNA predicts the response to immune checkpoint inhibitors cancer in lung cancer patientsPrincipal Investigator

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Long non cording RNA associated with drug resistance in lung cancer with driver mutationPrincipal Investigator

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Identification of serum exosomal microRNA in lung cancerPrincipal Investigator

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Prediction of drug sensitivity and development of a therapeutic strategy by microRNAs in lung cancerPrincipal Investigator

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肺癌治療におけるゲフィチニブ感受性予測法の開発Principal Investigator

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[Book] 抗癌剤の効果予測因子としてのバイオマーカー2010

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Seike Masahiro 清家正博

SEIKE Masahiro 清家正博

清家正博セイケマサヒロ