Kagabu Masahiro 利部正裕

Researcher Number	30382609
Other IDs	https://orcid.org/0000-0003-0926-1015
Affiliation (Current)	2023: 岩手医科大学, 医学部, 特任准教授
Affiliation (based on the past Project Information) *help	2020 – 2023: 岩手医科大学, 医学部, 講師 2018 – 2019: 岩手医科大学, 医学部, 特任講師 2016 – 2017: 岩手医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Obstetrics and gynecology
Keywords	Principal Investigator 腫瘍免疫 / 腫瘍溶解性ウイルス / 子宮癌肉腫 / 腫瘍免疫学 / 婦人科腫瘍学 / T細胞共刺激分子 / 子宮頸がん / 卵巣がん / 腫瘍浸潤リンパ球 / 免疫チェックポイント阻害薬 / 腫瘍溶解性ヘルペスウイルス / 子宮頸癌 / 卵巣癌 … More Except Principal Investigator … More 卵巣癌 / 明細胞癌 / HSP / MDSC / マウスモデル / 漿液性癌 / 子宮体癌 / NEFH / 治療標的 / KANK1 / 卵巣がん / シスプラチン / バイオマーカー / Aurora kinase A / 卵巣明細胞癌 Less

卵巣明細胞癌に対するＨＳＦ１経路を標的とした新規治療法の開発
- Principal Investigator
  
  板持広明
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Iwate Medical University
子宮癌肉腫に対する免疫逃避改善を誘導するウイルス療法の開発Principal Investigator
- Principal Investigator
  
  利部正裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Iwate Medical University
Development of tumor-host integrative therapies to overcome the refractory nature of uterine serous carcinoma
- Principal Investigator
  
  馬場長
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Iwate Medical University
卵巣明細胞癌に対するNEFHを標的とした新規治療法の開発
- Principal Investigator
  
  板持広明
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Iwate Medical University
The KANK1 pathway may be a novel therapeutic target for ovarian clear cell carcinoma
- Principal Investigator
  
  ITAMOCHI Hiroaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Iwate Medical University
Development of new viral therapy for improvement of immune escape mechanism in ovarian cancerPrincipal Investigator
- Principal Investigator
  
  Kagabu Masahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Iwate Medical University

All 2022 2021 2018 2017 2016

All Journal Article Presentation

[Journal Article] Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells.2022
- Author(s)
  Mise Y, Hamanishi J, Daikoku T, Takamatsu S, Miyamoto T, Taki M, Yamanoi K, Yamaguchi K, Ukita M, Horikawa N, Abiko K, Murakami R, Furutake Y, Hosoe Y, Terakawa J, Kagabu M, Sugai T, Osakabe M, Fujiwara H, Matsumura N, Mandai M, Baba T.
- Journal Title
  
  Carcinogenesis
  
  Volume: na Issue: 7 Pages: 647-658
- DOI
  10.1093/carcin/bgac032
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09287, KAKENHI-PROJECT-18H02947, KAKENHI-PROJECT-21K09548, KAKENHI-PROJECT-20K16431
[Journal Article] Novel therapeutic strategies for refractory ovarian cancers: Clear cell and mucinous carcinomas.2021
- Author(s)
  Shoji T, Tatsuki S, Abe M, Tomabechi H, Takatori E, Kaido Y, Nagasawa T, Kagabu M, Baba T, Itamochi H.
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 23 Pages: 6120-6120
- DOI
  10.3390/cancers13236120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09759
[Journal Article] Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study2021
- Author(s)
  Kagabu Masahiro、Nagasawa Takayuki、Tatsuki Shunsuke、Fukagawa Yasuko、Tomabechi Hidetoshi、Takatori Eriko、Kaido Yoshitaka、Shoji Tadahiro、Baba Tsukasa
- Journal Title
  
  Medicina
  
  Volume: 57 Issue: 6 Pages: 548-548
- DOI
  10.3390/medicina57060548
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09548
[Journal Article] Mast cells partially contribute to mucosal adjuvanticity of surfactin in mice.2018
- Author(s)
  Yoshino N, Takeshita R, Kawamura H, Sasaki Y, Kagabu M, Sugiyama T, Muraki Y, Sato S.
- Journal Title
  
  Immun Inflamm Dis.
  
  Volume: 6 Issue: 1 Pages: 117-127
- DOI
  10.1002/iid3.204
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15711
[Journal Article] Critical micelle concentration and particle size determine adjuvanticity of cyclic lipopeptides2018
- Author(s)
  Yoshino N, Takeshita R, Kawamura H, Murakami K, Sasaki Y, Sugiyama I, Sadzuka Y, Kagabu M, Sugiyama T, Muraki Y, Sato S.
- Journal Title
  
  Scandinavian Journal of Immunology
  
  Volume: 88 Issue: 2
- DOI
  10.1111/sji.12698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08445, KAKENHI-PROJECT-16K15711
[Journal Article] The efficacy of oncolytic herpes simplex viral therapy for uterine cervical cancer2018
- Author(s)
  Masahiro Kagabu, Naoto Yoshino, Tatsunori Saito, Yuki Miura, Ryosuke Takeshita, Kazuyuki Murakami, Hideki Kawamura, Tsukasa Baba, Toru Sugiyama
- Journal Title
  
  OncoTargets and Therapy(under review)
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15711
[Journal Article] 腫瘍溶解性ヘルペスウイルスとシクロホスファミドを併用した子宮頸がん新規治療法の検討2017
- Author(s)
  川村　英生，利部　正裕，佐々木　裕，村上　一行，川村　花恵，池田　浩，阿保　亜希子，吉野　直人，村木　靖，杉山　徹
- Journal Title
  
  岩手医学会雑誌
  
  Volume: 69
- NAID
  40021252419
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K15711
[Journal Article] 腫瘍溶解性ヘルペスウイルスとシクロホスファミドを併用した子宮頸がん新規治療法の検討2017
- Author(s)
  川村英生，利部正裕，佐々木裕，村上一行，川村花恵，池田浩，阿保亜希子，吉野直人，村木靖，杉山徹
- Journal Title
  
  岩手医学会雑誌
  
  Volume: 69 Pages: 75-88
- NAID
  40021252419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15711
[Journal Article] 腫瘍溶解性ウイルスと免疫チェックポイント阻害剤を併用した子宮頸がんに対する新規治療法の検討2016
- Author(s)
  村上　一行，利部　正裕，佐々木　裕，川村　花恵，川村　英生，吉野　直人，村木　靖，杉山　徹
- Journal Title
  
  岩手医学会雑誌
  
  Volume: 68 Pages: 113-130
- NAID
  40020971476
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 子宮頸がん検診によって発見された子宮頸部腺癌の検討2018
- Author(s)
  利部正裕
- Organizer
  日本臨床細胞学会総会
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 癌治療におけるCART 婦人科悪性腫瘍患者におけるCART療法2018
- Author(s)
  利部正裕
- Organizer
  日本アフェレシス学会学術講演会
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 子宮頸がんに対する腫瘍溶解性ウイルスと免疫チェックポイント阻害剤を併用した新規療法の検討2017
- Author(s)
  村上　一行，利部　正裕，佐々木　裕，川村　花恵，川村　英生，吉野　直人，村木　靖，杉山　徹
- Organizer
  第34回日本産婦人科感染症学会・学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良）
- Year and Date
  2017-05-20
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 子宮頸がんに対する腫瘍溶解性ウイルスと免疫チェックポイント阻害剤を併用した新規療法の検討2017
- Author(s)
  村上一行，利部正裕，佐々木裕，川村花恵，川村英生，吉野直人，村木靖，杉山徹
- Organizer
  第34回日本産婦人科感染症学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 子宮頸がんに対する化学療法とウイルス併用療法への基礎研究2017
- Author(s)
  川村英生, 利部正裕, 村上一行, 川村花恵, 板持広明, 杉山徹
- Organizer
  第68回日本産科婦人科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 腫瘍溶解性ウイルスと化学療法を併用した子宮頸がん新規治療法の検討2017
- Author(s)
  川村英生，利部正裕，佐々木裕，村上一行，川村花恵，池田浩，阿保亜希子，吉野直人，村木靖，杉山徹
- Organizer
  第34回日本産婦人科感染症学会・学術集会
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] Aurora-A inhibition synergistically enhances cisplatin induced cytotoxicity in ovarian clear cell carcinoma cell lines.2017
- Author(s)
  Chiba Y, Sato S, Fukagawa D, Suga Y, Kagabu M, Chiba A, Takeuchi S, Itamochi H, Sugai T, Sugiyama T.
- Organizer
  5th Biennial Meeting of Asian Society of Gynecologic Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11151
[Presentation] 腫瘍溶解性ウイルスと化学療法を併用した子宮頸がん新規治療法の検討2017
- Author(s)
  川村　英生，利部　正裕，佐々木　裕，村上　一行，川村　花恵，池田　浩，阿保　亜希子，吉野　直人，村木　靖，杉山　徹
- Organizer
  第34回日本産婦人科感染症学会・学術集会
- Place of Presentation
  奈良春日野国際フォーラム（奈良）
- Year and Date
  2017-05-20
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 子宮頸がんに対する単純ヘルペスウイルスを用いたウイルス療法と抗がん剤併用療法における基礎研究2016
- Author(s)
  川村英生, 利部正裕, 村上一行, 佐々木裕, 川村花恵, 吉野直人, 村木靖, 杉山徹
- Organizer
  第64回北日本産科婦人科学会総会・学術講演会
- Place of Presentation
  ロイトン札幌（札幌）
- Year and Date
  2016-09-17
- Data Source
  KAKENHI-PROJECT-16K15711
[Presentation] 子宮頸がんに対する腫瘍溶解性ウイルスと免疫チェックポイント阻害剤療法についての検討2016
- Author(s)
  村上　一行，利部　正裕，川村　花恵，川村　英生，杉山　徹
- Organizer
  第68回日本産科婦人科学会総会・学術講演会
- Place of Presentation
  東京国際フォーラム（東京）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K15711

1. ITAMOCHI Hiroaki (20314601)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. 馬場長 (60508240)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
3. 佐藤誠也 (30621007)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 杉山徹 (40162903)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
5. 小島淳美 (60508753)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 庄子忠宏 (00337148)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. 永沢崇幸 (10453309)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
8. 小見英夫 (20382608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 竹内聡 (60252772)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 吉野直人 (20372881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
11. 阿保亜紀子 (80326686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 苫米地英俊 (10771363)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 深川安寿子 (30772511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 菅井有 (20187628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大黒多希子 (30767249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 佐藤千絵 (70883726)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 万代昌紀 (80283597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 濱西潤三 (80378736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岩谷岳 (70405801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 遠藤史隆 (70714442)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 千葉洋平 (20892847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 村上隆介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kagabu Masahiro 利部 正裕

Research Projects

Research Products

Co-Researchers

卵巣明細胞癌に対するＨＳＦ１経路を標的とした新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

子宮癌肉腫に対する免疫逃避改善を誘導するウイルス療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of tumor-host integrative therapies to overcome the refractory nature of uterine serous carcinoma

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

卵巣明細胞癌に対するNEFHを標的とした新規治療法の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The KANK1 pathway may be a novel therapeutic target for ovarian clear cell carcinoma

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of new viral therapy for improvement of immune escape mechanism in ovarian cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel therapeutic strategies for refractory ovarian cancers: Clear cell and mucinous carcinomas.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of Postoperative Adjuvant Chemotherapy and Concurrent Chemoradiotherapy for FIGO2018 Stage IIIC1 Cervical Cancer: A Retrospective Study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mast cells partially contribute to mucosal adjuvanticity of surfactin in mice.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Critical micelle concentration and particle size determine adjuvanticity of cyclic lipopeptides2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The efficacy of oncolytic herpes simplex viral therapy for uterine cervical cancer2018

Author(s)

Journal Title

Data Source

[Journal Article] 腫瘍溶解性ヘルペスウイルスとシクロホスファミドを併用した 子宮頸がん新規治療法の検討2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 腫瘍溶解性ヘルペスウイルスとシクロホスファミドを併用した 子宮頸がん新規治療法の検討2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] 腫瘍溶解性ウイルスと免疫チェックポイント阻害剤を併用した子宮頸がんに対する新規治療法の検討2016

Kagabu Masahiro 利部正裕

[Journal Article] 腫瘍溶解性ヘルペスウイルスとシクロホスファミドを併用した子宮頸がん新規治療法の検討2017

[Journal Article] 腫瘍溶解性ヘルペスウイルスとシクロホスファミドを併用した子宮頸がん新規治療法の検討2017

[Presentation] 子宮頸がんに対する腫瘍溶解性ウイルスと免疫チェックポイント阻害剤を併用した新規療法の検討2017