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Inoue Keiichi  井上 敬一

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INOUE Keiichi  井上 敬一

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Researcher Number 30396981
Other IDs
Affiliation (Current) 2025: 九州大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help 2023 – 2024: 九州大学, 医学研究院, 助教
2022 – 2023: 新潟大学, 医学部, 医学部准教授
2019 – 2022: 新潟大学, 医歯学系, 特任助教
2005: 医科歯科大, 難治疾患研究所, 助手
2005: Tokyo Medical and Dental University, Medical Research Institute, Molecular Pharmacology, 難治疾患研究所, 助手
Review Section/Research Field
Principal Investigator
Basic Section 59010:Rehabilitation science-related / Transformative Research Areas, Section (III) / 0802:Biomedical structure and function and related fields / Medium-sized Section 49:Pathology, infection/immunology, and related fields / General anatomy (including Histology/Embryology)
Except Principal Investigator
Basic Section 44010:Cell biology-related / Orthopaedic surgery
Keywords
Principal Investigator
マイトファジー / マウス / ミトコンドリア / 骨格筋 / 臨界期 / 細胞老化 / 遺伝子改変マウス / 線維芽細胞 / 老化 / 前頭側頭型認知症 … More / 筋萎縮性側索硬化症 / オートファジー誘導 / 神経変性疾患 / RNA foci / オートファジー / 廃用性筋萎縮 / アデノ随伴ウイルス / ゲノムワイドスクリーニング / 筋萎縮 / 遺伝子治療 … More
Except Principal Investigator
マイトファジー / オートファジー / ミトコンドリア / stem cell / cartilage / transcriptionfactor / bone resumption / bone formation / osteoporosis / osteoclast / osteoblast / Smad / 低骨量状態 / BMP / 石灰化速度 / 骨形成速度 / 外骨膜 / 海綿骨 / 骨塩量 / マトリックス / オステオポンチン / 副甲状腺ホルモン / エストロジェン / 卵巣摘除 / ノックアウトマウス / Tob / 閉経後骨粗鬆症 / 骨折 / βブロッカー / 交感神経系 / 骨量 / 幹細胞 / 軟骨 / 転写因子 / 骨吸収 / 骨形成 / 骨粗鬆症 / 破骨細胞 / 骨芽細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (8 People)
  •  マイトファジーによる骨格筋ミトコンドリアネットワークの再構成とその治療応用Principal Investigator

    • Principal Investigator
      井上 敬一
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyushu University
  •  マイトファジーによる臨界期の調節とその再開Principal Investigator

    • Principal Investigator
      井上 敬一
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Kyushu University
      Niigata University
  •  レセプター依存的マイトファジーの誘導制御と生理機能の解明

    • Principal Investigator
      神吉 智丈
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44010:Cell biology-related
    • Research Institution
      Kyushu University
      Niigata University
  •  Mitophagy-mediated gene therapy for muscle atrophyPrincipal Investigator

    • Principal Investigator
      Inoue Keiichi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Kyushu University
      Niigata University
  •  Establishment of autophagy-inducing system to degrade RNA fociPrincipal Investigator

    • Principal Investigator
      Inoue Keiichi
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 49:Pathology, infection/immunology, and related fields
    • Research Institution
      Niigata University
  •  Mitochondrial Autophagy in AgingPrincipal Investigator

    • Principal Investigator
      Inoue Keiichi
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0802:Biomedical structure and function and related fields
    • Research Institution
      Niigata University
  •  骨細胞ネットワークによる新規の骨石灰化メカニズムの解明Principal Investigator

    • Principal Investigator
      井上 敬一
    • Project Period (FY)
      2005
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General anatomy (including Histology/Embryology)
    • Research Institution
      Tokyo Medical and Dental University
  •  Molecular Bases for Bone Regeneration Research

    • Principal Investigator
      NODA Masaki
    • Project Period (FY)
      2002 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2022 2021 2020 2019

All Journal Article

  • [Journal Article] Mitophagy mediated by BNIP3 and NIX protects against ferroptosis by downregulating mitochondrial reactive oxygen species2024

    • Author(s)
      Yamashita Shun-ichi、Sugiura Yuki、Matsuoka Yuta、Maeda Rae、Inoue Keiichi、Furukawa Kentaro、Fukuda Tomoyuki、Chan David C.、Kanki Tomotake
    • Journal Title

      Cell Death & Differentiation

      Volume: - Issue: 5 Pages: 651-661

    • DOI

      10.1038/s41418-024-01280-y

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07207, KAKENHI-PROJECT-23K06080, KAKENHI-PROJECT-21K05500, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23878
  • [Journal Article] Hva22, a REEP family protein in fission yeast, promotes reticulophagy in collaboration with a receptor protein2023

    • Author(s)
      Fukuda Tomoyuki、Saigusa Tetsu、Furukawa Kentaro、Inoue Keiichi、Yamashita Shun-ichi、Kanki Tomotake
    • Journal Title

      Autophagy

      Volume: 19 Issue: 10 Pages: 2657-2667

    • DOI

      10.1080/15548627.2023.2214029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K05679, KAKENHI-PROJECT-21K05500, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23878
  • [Journal Article] マイトファジーとミトコンドリア病2022

    • Author(s)
      井上敬一、神吉智丈
    • Journal Title

      週間医学のあゆみ

      Volume: 281 Pages: 1145-1150

    • Data Source
      KAKENHI-PROJECT-20H04035
  • [Journal Article] Mitophagy reporter mouse analysis reveals increased mitophagy activity in disuse‐induced muscle atrophy2021

    • Author(s)
      Yamashita Shun‐Ichi、Kyuuma Masanao、Inoue Keiichi、Hata Yuki、Kawada Ryu、Yamabi Masaki、Fujii Yasuyuki、Sakagami Junko、Fukuda Tomoyuki、Furukawa Kentaro、Tsukamoto Satoshi、Kanki Tomotake
    • Journal Title

      Journal of Cellular Physiology

      Volume: N/A Issue: 11 Pages: 7612-7624

    • DOI

      10.1002/jcp.30404

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K23822, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-21K05500
  • [Journal Article] CRISPR-activated patient fibroblasts for modeling of familial Alzheimer's disease2021

    • Author(s)
      Inoue Keiichi
    • Journal Title

      Neuroscience Research

      Volume: N/A Pages: 7-12

    • DOI

      10.1016/j.neures.2021.03.008

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K23822
  • [Journal Article] クリスパー転写活性化によるアルツハイマー病線維芽細胞モデルの作製2020

    • Author(s)
      井上敬一
    • Journal Title

      CLINICAL NEUROSCIENCE

      Volume: 38 Pages: 1052-1054

    • Data Source
      KAKENHI-PROJECT-19K23822
  • [Journal Article] Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast2020

    • Author(s)
      Fukuda Tomoyuki、Ebi Yuki、Saigusa Tetsu、Furukawa Kentaro、Yamashita Shun-ichi、Inoue Keiichi、Kobayashi Daiki、Yoshida Yutaka、Kanki Tomotake
    • Journal Title

      eLife

      Volume: 9

    • DOI

      10.7554/elife.61245

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06552, KAKENHI-PROJECT-19K22419, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18K06129, KAKENHI-PROJECT-19K23822
  • [Journal Article] Association and dissociation between the mitochondrial Far complex and Atg32 regulate mitophagy2020

    • Author(s)
      Innokentev Aleksei、Furukawa Kentaro、Fukuda Tomoyuki、Saigusa Tetsu、Inoue Keiichi、Yamashita Shun-ichi、Kanki Tomotake
    • Journal Title

      eLife

      Volume: 9

    • DOI

      10.7554/elife.63694

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K22419, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-18K06129, KAKENHI-PROJECT-19K23822
  • [Journal Article] Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1.2020

    • Author(s)
      Igarashi R, Yamashita SI, Yamashita T, Inoue K, Fukuda T, Fukuchi T, Kanki T.
    • Journal Title

      Sci Rep.

      Volume: 10(1) Issue: 1 Pages: 1465-1465

    • DOI

      10.1038/s41598-020-58315-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09399, KAKENHI-PROJECT-19K22419, KAKENHI-PROJECT-19K23822, KAKENHI-PROJECT-16KK0162, KAKENHI-PROJECT-16H06276, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-17H03671
  • [Journal Article] Glaucoma-Associated Mutations in the Optineurin Gene Have Limited Impact on Parkin-Dependent Mitophagy.2019

    • Author(s)
      Chernyshova K, Inoue K, Yamashita SI, Fukuchi T, Kanki T.
    • Journal Title

      Invest Ophthalmol Vis Sci.

      Volume: 60(10) Issue: 10 Pages: 3625-3635

    • DOI

      10.1167/iovs.19-27184

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09399, KAKENHI-PROJECT-19K23822, KAKENHI-PROJECT-16KK0162, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-18H04691, KAKENHI-PROJECT-17H03671, KAKENHI-PUBLICLY-18H04858
  • [Journal Article] 哺乳類におけるミトコンドリアオートファジーの分子機構2019

    • Author(s)
      井上敬一、山下俊一、神吉智丈
    • Journal Title

      実験医学増刊

      Volume: 37 Pages: 58-64

    • Data Source
      KAKENHI-PROJECT-19K23822
  • [Journal Article] ミトコンドリアオートファジーと老化との関連2019

    • Author(s)
      神吉智丈、井上敬一
    • Journal Title

      FRAGRANCE JOURNAL

      Volume: 47 Pages: 36-39

    • Data Source
      KAKENHI-PROJECT-19K23822
  • 1.  NODA Masaki (50231725)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  NIFUJI Akira (00240747)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  TSUJI Kunikazu (20323694)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  瀬原 吉英 (50721156)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  神吉 智丈 (50398088)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  山下 俊一 (30529095)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  福田 智行 (90415282)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  福地 健郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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