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warita hitoshi  割田 仁

… Alternative Names

WARITA Hitoshi  割田 仁

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Researcher Number 30400245
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-7934-3863
Affiliation (Current) 2025: 東北大学, 医学系研究科, 大学院非常勤講師
Affiliation (based on the past Project Information) *help 2024: 東北大学, 医学系研究科, 准教授
2017 – 2023: 東北大学, 大学病院, 助教
2016: 東北大学, 医学系研究科, 助教
2015: 東北大学, 大学院医学系研究科, 助教
2011 – 2015: 東北大学, 医学(系)研究科(研究院), 助教 … More
2008 – 2009: Tohoku University, 大学院・医学系研究科, 助教
2007: Tohoku University, 大学院・医学研究科, 助教
2006: 東北大学, 大学院・医学系研究科, 助手 Less
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 52020:Neurology-related
Except Principal Investigator
Basic Section 52020:Neurology-related / Neurology / Medium-sized Section 52:General internal medicine and related fields
Keywords
Principal Investigator
運動ニューロン / 神経変性 / 神経再生 / 筋萎縮性側索硬化症 / 臨床神経分子遺伝学 / 動物モデル / トランスクリプトーム / オミックス解析 / hnRNP / RNA結合蛋白 … More / 骨格筋 / 多系統蛋白質症 / 代謝異常 / iPS細胞 / リピドーム / 脳神経疾患 / 再生医学 / 神経科学 / 神経炎症 / アストロサイト / ペリサイト / 血管新生 / 再生 … More
Except Principal Investigator
封入体筋炎 / iPS細胞 / 筋萎縮性側索硬化症 / 運動ニューロン / ALS / 軸索変性 / RNAシークエンス / オミックス解析 / プロテアソーム / 神経変性 / 運動単位 / タンパク異常凝集 / トランスクリプトーム / 軸索編成 / オミックス / 軸索再生 / 筋芽細胞 / 筋収縮 / 細胞内凝集体 / 電気収縮 / 骨格筋生物学 / TDP-43 / 電気収縮培養 / マイクロ流体デバイス / 軸索病態 / RNA代謝 / FUS / 軸索レジリエンス / 運動ニューロン軸索 / 軸索 / 共培養モデル / 次世代シークエンサー / 筋疾患 / RNA結合蛋白 / 封入体ミオパチー / 多系統蛋白質症 / 骨格筋 / RNA / 神経変性疾患 / ALS Less
  • Research Projects

    (18 results)
  • Research Products

    (120 results)
  • Co-Researchers

    (14 People)
  •  Elucidating the pathology of amyotrophic lateral sclerosis by targeting pre-symptomatic lipid dysmetabolismPrincipal Investigator

    • Principal Investigator
      割田 仁
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Elucidation of the molecular pathogenesis of ALS using a motor neuron-skeletal muscle cell model

    • Principal Investigator
      青木 正志
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Aberrant RNA splicing in sporadic inclusion body myositis

    • Principal Investigator
      青木 正志
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tohoku University
  •  Elucidation of the Molecular Basis of Axonal Branching Abnormalities in Amyotrophic Lateral Sclerosis Models

    • Principal Investigator
      Suzuki Naoki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Axonal degeneration and regeneration as common cell type-selective therapeutic targets in ALS

    • Principal Investigator
      Aoki Masashi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Elucidation of the pathogenesis of inclusion body myositis by focusing on the abnormal aggregation protein clearance system

    • Principal Investigator
      AOKI Masashi
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tohoku University
  •  Elucidation of the molecular pathogenesis of selective degeneration in multisystem proteinopathy and amyotrophic lateral sclerosis.Principal Investigator

    • Principal Investigator
      Warita Hitoshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Analysis of axonal pathomechanism in amyotrophic lateral sclerosis using human iPS cell-derived nerve organoid.

    • Principal Investigator
      Suzuki Naoki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Tohoku University
  •  Elucidating the mechanism of abnormal protein aggregation in sporadic inclusion body myositis by single molecule nanoimaging

    • Principal Investigator
      Aoki Masashi
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 52:General internal medicine and related fields
    • Research Institution
      Tohoku University
  •  In vivo differentiation control of endogenous neural cells in ALSPrincipal Investigator

    • Principal Investigator
      Warita Hitoshi
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Unraveling common mechanisms underlying neuromuscular degeneration in multisystem proteinopathy

    • Principal Investigator
      Aoki Masashi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Elucidating the molecular pathology of inclusion body myositis using novel culture system and next generation sequencer

    • Principal Investigator
      Aoki Masashi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Microvascular pericytes: possible regenerative targets in ALSPrincipal Investigator

    • Principal Investigator
      WARITA Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Genetic analysis and establishment of in vitro model for inclusion body myositis

    • Principal Investigator
      Aoki Masashi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Elucidating the RNA pathomechanism in FUS-FALS iPS induced motor neurons

    • Principal Investigator
      Aoki Masashi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  Gliogenesis and angiogenesis: possible regenerative targets in spinal cord of a transgenic model of ALSPrincipal Investigator

    • Principal Investigator
      WARITA Hitoshi
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  A possible role of angiogenesis in the spinal cord microvasculaturefor spinal motor neuroprotection in ALSPrincipal Investigator

    • Principal Investigator
      WARITA Hitoshi
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University
  •  ALSラットモデル脊髄におけるニューロン新生の検索Principal Investigator

    • Principal Investigator
      割田 仁
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurology
    • Research Institution
      Tohoku University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book Patent Other

  • [Book] 脳神経疾患最新の治療2021-20232020

    • Author(s)
      割田 仁,青木正志(分担執筆,園生雅弘・北川一夫・青木正志 共同編集)
    • Total Pages
      368
    • Publisher
      南江堂
    • ISBN
      4524227857
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Book] アクチュアル脳・神経疾患の臨床 小脳と運動失調 小脳はなにをしているのか 「皮質性小脳萎縮症」2013

    • Author(s)
      割田 仁, 青木正志 (総編集 辻 省次,専門編集 西澤正豊)
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Book] アクチュアル脳・神経疾患の臨床小脳と運動失調小脳はなにをしているのか「皮質性小脳萎縮症」2013

    • Author(s)
      割田仁、青木正志(総編集辻省次、専門編集西澤正豊)
    • Publisher
      中山書店
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Book] 「再生医療技術の最前線」軟組織・中枢神経2007

    • Author(s)
      割田 仁, ら
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-18790586
  • [Journal Article] Nationwide survey of patients with multisystem proteinopathy in Japan2024

    • Author(s)
      Yamashita Satoshi、Takahashi Yuji、Hashimoto Jun、Murakami Ayuka、Nakamura Ryoichi、Katsuno Masahisa、Izumi Rumiko、Suzuki Naoki、Warita Hitoshi、Aoki Masashi、the Japan MSP Study Group
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: - Issue: 4 Pages: 938-945

    • DOI

      10.1002/acn3.52011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-19K07973, KAKENHI-PROJECT-22K07509, KAKENHI-PROJECT-18K07491, KAKENHI-PROJECT-21K07411
  • [Journal Article] Comprehensive Analysis of a Japanese Pedigree with Biallelic ACAGG Expansions in RFC1 Manifesting Motor Neuronopathy with Painful Muscle Cramps2024

    • Author(s)
      Izumi Rumiko、Warita Hitoshi、Niihori Tetsuya、Furusawa Yoshihiko、Nakano Misa、Oya Yasushi、Kato Kazuhiro、Shiga Takuro、Ikeda Kensuke、Suzuki Naoki、Nishino Ichizo、Aoki Yoko、Aoki Masashi
    • Journal Title

      The Cerebellum

      Volume: - Issue: 4 Pages: 1498-1508

    • DOI

      10.1007/s12311-024-01666-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K18260
  • [Journal Article] Phase II/III Study of Aceneuramic Acid Administration for GNE Myopathy in Japan2023

    • Author(s)
      Suzuki Naoki、Mori-Yoshimura Madoka、Katsuno Masahisa、Takahashi Masanori P.、Yamashita Satoshi、Oya Yasushi、Hashizume Atsushi、Yamada Shinichiro、Nakamori Masayuki、Izumi Rumiko、Kato Masaaki、Warita Hitoshi、Tateyama Maki、Kuroda Hiroshi、Asada Ryuta、Yamaguchi Takuhiro、Nishino Ichizo、Aoki Masashi
    • Journal Title

      Journal of Neuromuscular Diseases

      Volume: - Issue: 4 Pages: 1-12

    • DOI

      10.3233/jnd-230029

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-19K22597
  • [Journal Article] Efficacy confirmation study of aceneuramic acid administration for GNE myopathy in Japan2023

    • Author(s)
      Mori-Yoshimura Madoka、Suzuki Naoki、Katsuno Masahisa、Takahashi Masanori P.、Yamashita Satoshi、Oya Yasushi、Hashizume Atsushi、Yamada Shinichiro、Nakamori Masayuki、Izumi Rumiko、Kato Masaaki、Warita Hitoshi、Tateyama Maki、Kuroda Hiroshi、Asada Ryuta、Yamaguchi Takuhiro、Nishino Ichizo、Aoki Masashi
    • Journal Title

      Orphanet Journal of Rare Diseases

      Volume: 18 Issue: 1 Pages: 241-241

    • DOI

      10.1186/s13023-023-02850-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-19K22597
  • [Journal Article] Nuclear pore pathology underlying multisystem proteinopathy type 3‐related inclusion body myopathy2023

    • Author(s)
      Izumi Rumiko、Ikeda Kensuke、Niihori Tetsuya、Suzuki Naoki、Shirota Matsuyuki、Funayama Ryo、Nakayama Keiko、Warita Hitoshi、Tateyama Maki、Aoki Yoko、Aoki Masashi
    • Journal Title

      Annals of Clinical and Translational Neurology

      Volume: 11 Issue: 3 Pages: 577-592

    • DOI

      10.1002/acn3.51977

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K18260, KAKENHI-PROJECT-22K12241, KAKENHI-PROJECT-21K07411
  • [Journal Article] Genetics of amyotrophic lateral sclerosis: seeking therapeutic targets in the era of gene therapy2022

    • Author(s)
      Suzuki Naoki、Nishiyama Ayumi、Warita Hitoshi、Aoki Masashi
    • Journal Title

      Journal of Human Genetics

      Volume: 68 Issue: 3 Pages: 131-152

    • DOI

      10.1038/s10038-022-01055-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07411
  • [Journal Article] Malignant otitis externa presenting cerebral infarction from pseudoaneurysm: A case report and a review of the literature2022

    • Author(s)
      Koshiba Y, Ikeda R, Suzuki J, Honkura Y, Funayama Y, Ikeda K, Warita H, Aoki M, Kawase T, Katori Y.
    • Journal Title

      Clinical Case Reports

      Volume: 10 Issue: 2

    • DOI

      10.1002/ccr3.5276

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Journal Article] Long-term outcomes after surgery to prevent aspiration for patients with amyotrophic lateral sclerosis2022

    • Author(s)
      Soga T, Suzuki N, Kato K, Kawamoto-Hirano A, Kawauchi Y, Izumi R, Toyoshima M, Mitsuzawa S, Shijo T, Ikeda K, Warita H, Katori Y, Aoki M, Kato M.
    • Journal Title

      BMC Neurology

      Volume: 22 Issue: 1 Pages: 94-94

    • DOI

      10.1186/s12883-022-02619-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Journal Article] MOG Antibody-Associated Disorders Following SARS- CoV-2 Vaccination: A Case Report and Literature Review.2022

    • Author(s)
      Matsumoto Y, Ohyama A, Kubota T, Ikeda K, Kaneko K, Takai Y, Warita H, Takahashi T, Misu T, Aoki M.
    • Journal Title

      Front Neurol.

      Volume: 13 Pages: 845755-845755

    • DOI

      10.3389/fneur.2022.845755

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07953, KAKENHI-PROJECT-20K07897
  • [Journal Article] RNP顆粒生成・分解からみた多系統蛋白質症2021

    • Author(s)
      割田仁, 池田謙輔, 青木正志
    • Journal Title

      脳神経内科

      Volume: 95 Pages: 112-120

    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Journal Article] A novel deletion in the C-terminal region of HSPB8 in a family with rimmed vacuolar myopathy2021

    • Author(s)
      Inoue-Shibui Aya、Niihori Tetsuya、Kobayashi Michio、Suzuki Naoki、Izumi Rumiko、Warita Hitoshi、Hara Kenju、Shirota Matsuyuki、Funayama Ryo、Nakayama Keiko、Nishino Ichizo、Aoki Masashi、Aoki Yoko
    • Journal Title

      Journal of Human Genetics

      Volume: NA Issue: 10 Pages: 965-972

    • DOI

      10.1038/s10038-021-00916-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-20H03637, KAKENHI-PROJECT-20K16571, KAKENHI-PROJECT-20K07897
  • [Journal Article] Randomized phase 2 study of perampanel for sporadic amyotrophic lateral sclerosis2021

    • Author(s)
      Aizawa H, Kato H, Oba K, Kawahara T, Okubo Y, Saito T, Naito M, Urushitani M, Tamaoka A, Nakamagoe K, Ishii K, Kanda T, Katsuno M, Atsuta N, Maeda Y, Nagai M, Nishiyama K, Ishiura H, Toda T, Kawata A, Abe K, Yabe I, Takahashi-Iwata I, Sasaki H, Warita H, Aoki M, Sobue G, Mizusawa H, Matsuyama Y, Haga T, Kwak S
    • Journal Title

      Journal of Neurology

      Volume: 269 Issue: 2 Pages: 885-896

    • DOI

      10.1007/s00415-021-10670-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07537, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20K07897
  • [Journal Article] Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations2021

    • Author(s)
      Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Shirota M, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Osana S, Nakagawa T, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Warita H, Okano H, Aoki M.
    • Journal Title

      Stem Cell Reports

      Volume: 16 Issue: 6 Pages: 1527-1541

    • DOI

      10.1016/j.stemcr.2021.04.021

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K05288, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-21K07411, KAKENHI-PROJECT-20K16593, KAKENHI-PROJECT-20K19478, KAKENHI-PROJECT-20K07897
  • [Journal Article] An Amyotrophic Lateral Sclerosis-Associated Mutant of C21ORF2 Is Stabilized by NEK1-Mediated Hyperphosphorylation and the Inability to Bind FBXO32020

    • Author(s)
      Watanabe Y, Nakagawa T, Akiyama T, Nakagawa M, Suzuki N, Warita H, Aoki M, Nakayama K.
    • Journal Title

      iScience

      Volume: 23 Issue: 9 Pages: 1-15

    • DOI

      10.1016/j.isci.2020.101491

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07837, KAKENHI-PROJECT-20K12157, KAKENHI-PROJECT-17K10432, KAKENHI-PROJECT-20K07897
  • [Journal Article] Generation of an ALS human iPSC line KEIOi001-A from peripheral blood of a Charcot disease-affected patient carrying TARDBP p.N345K heterozygous SNP mutation2020

    • Author(s)
      Leventoux Nicolas、Morimoto Satoru、Hara Kenju、Nakamura Shiho、Ozawa Fumiko、Mitsuzawa Shio、Akiyama Tetsuya、Nishiyama Ayumi、Suzuki Naoki、Warita Hitoshi、Aoki Masashi、Okano Hideyuki
    • Journal Title

      Stem Cell Research

      Volume: 47 Pages: 101896-101896

    • DOI

      10.1016/j.scr.2020.101896

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-19K17002, KAKENHI-PROJECT-20K07897
  • [Journal Article] Omics Approach to Axonal Dysfunction of Motor Neurons in Amyotrophic Lateral Sclerosis (ALS)2020

    • Author(s)
      Suzuki Naoki、Akiyama Tetsuya、Warita Hitoshi、Aoki Masashi
    • Journal Title

      Frontiers in Neuroscience

      Volume: 14

    • DOI

      10.3389/fnins.2020.00194

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07519
  • [Journal Article] The genetic profile of dysferlinopathy in a cohort of 209 cases: Genotype-phenotype relationship and a hotspot on the inner DysF domain2020

    • Author(s)
      Izumi Rumiko、Takahashi Toshiaki、Suzuki Naoki、Niihori Tetsuya、Ono Hiroya、Nakamura Naoko、Katada Shinichi、Kato Masaaki、Warita Hitoshi、Tateyama Maki、Aoki Yoko、Aoki Masashi
    • Journal Title

      Human Mutation

      Volume: 41 Issue: 9 Pages: 1540-1554

    • DOI

      10.1002/humu.24036

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-18K15437
  • [Journal Article] AMPK Complex Activation Promotes Sarcolemmal Repair in Dysferlinopathy2020

    • Author(s)
      Ono Hiroya、Suzuki Naoki、Kanno Shin-ichiro、Kawahara Genri、Izumi Rumiko、Takahashi Toshiaki、Kitajima Yasuo、Osana Shion、Nakamura Naoko、Akiyama Tetsuya、Ikeda Kensuke、Shijo Tomomi、Mitsuzawa Shio、Nagatomi Ryoichi、Araki Nobukazu、Yasui Akira、Warita Hitoshi、Hayashi Yukiko K.、Miyake Katsuya、Aoki Masashi
    • Journal Title

      Molecular Therapy

      Volume: 28 Issue: 4 Pages: 1133-1153

    • DOI

      10.1016/j.ymthe.2020.02.006

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06831, KAKENHI-PROJECT-19K22604, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18K19505, KAKENHI-PROJECT-17K16107, KAKENHI-PROJECT-18K10822, KAKENHI-PROJECT-20K21563, KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-18K15437, KAKENHI-PROJECT-20H03594, KAKENHI-PROJECT-20H04078
  • [Journal Article] 増大特集 ALS2019 家族性ALS2019

    • Author(s)
      鈴木 直輝、西山 亜由美、加藤 昌昭、割田 仁、青木 正志
    • Journal Title

      BRAIN and NERVE

      Volume: 71 Issue: 11 Pages: 1169-1181

    • DOI

      10.11477/mf.1416201427

    • ISSN
      1344-8129, 1881-6096
    • Year and Date
      2019-11-01
    • Data Source
      KAKENHI-PROJECT-18K07519
  • [Journal Article] Interstitial pneumonia and other adverse events in riluzole-administered amyotrophic lateral sclerosis patients: a retrospective observational study2019

    • Author(s)
      Inoue-Shibui Aya、Kato Masaaki、Suzuki Naoki、Kobayashi Junpei、Takai Yoshiki、Izumi Rumiko、Kawauchi Yuuko、Kuroda Hiroshi、Warita Hitoshi、Aoki Masashi
    • Journal Title

      BMC Neurology

      Volume: 19 Issue: 1 Pages: 72-78

    • DOI

      10.1186/s12883-019-1299-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-17K16107
  • [Journal Article] Antagonizing bone morphogenetic protein 4 attenuates disease progression in a rat model of amyotrophic lateral sclerosis2018

    • Author(s)
      Shijo Tomomi、Warita Hitoshi、Suzuki Naoki、Ikeda Kensuke、Mitsuzawa Shio、Akiyama Tetsuya、Ono Hiroya、Nishiyama Ayumi、Izumi Rumiko、Kitajima Yasuo、Aoki Masashi
    • Journal Title

      Experimental Neurology

      Volume: 307 Pages: 164-179

    • DOI

      10.1016/j.expneurol.2018.06.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07519, KAKENHI-PROJECT-18K17857, KAKENHI-PROJECT-16J00431, KAKENHI-PROJECT-15K16486, KAKENHI-PROJECT-17K09773
  • [Journal Article] TARDBP p.G376D mutation, found in rapid progressive familial ALS, induces mislocalization of TDP-432018

    • Author(s)
      Mitsuzawa Shio、Akiyama Tetsuya、Nishiyama Ayumi、Suzuki Naoki、Kato Masaaki、Warita Hitoshi、Izumi Rumiko、Osana Shion、Koyama Shingo、Kato Takeo、Suzuki Yoshihiro、Aoki Masashi
    • Journal Title

      eNeurologicalSci

      Volume: 11 Pages: 20-22

    • DOI

      10.1016/j.ensci.2018.04.001

    • Data Source
      KAKENHI-PROJECT-18K07519
  • [Journal Article] Comprehensive targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis.2017

    • Author(s)
      Nisiyama A, Niihori T, Warita H, Izumi R, Akiyama T, Kato M, Suzuki N, Aoki Y, Aoki M.
    • Journal Title

      Neurobiol Aging

      Volume: 53 Pages: 194.e1-194.e8

    • DOI

      10.1016/j.neurobiolaging.2017.01.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05318, KAKENHI-PROJECT-26461288, KAKENHI-PROJECT-15H05667
  • [Journal Article] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016

    • Author(s)
      Naoki Ichiyanagi, Koki Fujimori, Masato Yano, Chikako Ishihara-Fujisaki, Takefumi Sone, Tetsuya Akiyama, Yohei Okada, Wado Akamatsu, Takuya Matsumoto, Mitsuru Ishikawa, Yoshinori Nishimoto, Yasuharu Ishihara, Tetsushi Sakuma, Takashi Yamamoto, Hitomi Tsuiji, Naoki Suzuki, Hitoshi Warita, Masashi Aoki, Hideyuki Okano
    • Journal Title

      Stem Cell Reports

      Volume: 6 Issue: 4 Pages: 496-510

    • DOI

      10.1016/j.stemcr.2016.02.011

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06924, KAKENHI-PROJECT-25430055, KAKENHI-PROJECT-26830018, KAKENHI-PROJECT-15H04278, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199, KAKENHI-PLANNED-26117007, KAKENHI-PUBLICLY-15H01568, KAKENHI-PROJECT-25640038, KAKENHI-PROJECT-16K07247
  • [Journal Article] Prominent sensory involvement in a case of familial amyotrophic lateral sclerosis carrying the L8V SOD1 mutation.2016

    • Author(s)
      Nisiyama A, Warita H, Takahashi T, Suzuki N, Nishiyama S, Tano O, Akiyama T, Watanabe Y, Takahashi K, Kuroda H, Kato M, Tateyama M, Niihori T, Aoki Y, Aoki M.
    • Journal Title

      Clin Neurol Neurosurg

      Volume: 150 Pages: 194-196

    • DOI

      10.1016/j.clineuro.2016.08.008

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05318, KAKENHI-PROJECT-26461288
  • [Journal Article] Genotype-phenotype relationships in familial ALS with FUS/TLS mutations in Japan2016

    • Author(s)
      Akiyama T, Warita H, Kato M, Nishiyama A, Izumi R, Ikeda C, Kamada M, Suzuki N, Aoki M
    • Journal Title

      Muscle Nerve

      Volume: Jan 28 Issue: 3 Pages: 398-404

    • DOI

      10.1002/mus.25061

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26461288, KAKENHI-PROJECT-15H05667, KAKENHI-PROJECT-25293199
  • [Journal Article] Multicenter questionnaire survey for sporadic inclusion body myositis in Japan.2016

    • Author(s)
      Suzuki N, Mori-Yoshimura M, Yamashita S, Nakano S, Murata KY, Inamori Y, Matsui N, Kimura E, Kusaka H, Kondo T, Higuchi I, Kaji R, Tateyama M, Izumi R, Ono H, Kato M, Warita H, Takahashi T, Nishino I, Aoki M.
    • Journal Title

      Orphanet J Rare Dis.

      Volume: 11 Issue: 1 Pages: 146-146

    • DOI

      10.1186/s13023-016-0524-x

    • NAID

      120006937646

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09674, KAKENHI-PROJECT-16K15474
  • [Journal Article] A mutation in hnRNPA1 causes isolated inclusion body myopathy in two families with multisystem proteinopathy2015

    • Author(s)
      Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
    • Journal Title

      Neurology Genetics

      Volume: NA

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25293199
  • [Journal Article] Genetic profile for suspected dysferlinopathy identified by targeted next generation sequencing2015

    • Author(s)
      Izumi R, Niihori T, Takahashi T, Suzuki N, Tateyama M, Watanabe C, Sugie K, Nakanishi H, Sobue G, Kato M, Warita H, Aoki Y, Aoki M
    • Journal Title

      Neurol Genet

      Volume: 1(4) Issue: 4

    • DOI

      10.1212/nxg.0000000000000036

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461288, KAKENHI-PROJECT-25461323
  • [Journal Article] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation2015

    • Author(s)
      Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M
    • Journal Title

      Neurol Genet

      Volume: 1(3) Issue: 3

    • DOI

      10.1212/nxg.0000000000000023

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Journal Article] A mutation in hnRNPA1 causes isolated inclusion body myopathy in two families with multisystem proteinopathy2015

    • Author(s)
      Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
    • Journal Title

      Neurology Genetics

      Volume: NA

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26670436
  • [Journal Article] Proteasome dysfunction induces muscle growth defects and protein aggregation2014

    • Author(s)
      Kitajima Y, Tashiro Y, Suzuki N, Warita H, Kato M, Tateyama M, Ando R, Izumi R, Yamazaki M, Abe M, Sakimura K, Ito H, Urushitani M, Nagatomi R, Takahashi R, and Aoki M
    • Journal Title

      J Cell Sci

      Volume: 127 Pages: 5204-5217

    • DOI

      10.1242/jcs.150961

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26290023, KAKENHI-PROJECT-26350979, KAKENHI-PROJECT-26670436
  • [Journal Article] Exome sequencing identifies a novel TTN mutation in a family with hereditary myopathy with early respiratory failure2013

    • Author(s)
      Izumi R, Niihori T, Aoki Y, Suzuki N, Kato M, Warita H, Takahashi T, Tateyama M, Nagashima T, Funayama R, Abe K, Nakayama K, Aoki M, Matsubara Y
    • Journal Title

      J Hum Genet

      Volume: 58(5) Issue: 5 Pages: 259-66

    • DOI

      10.1038/jhg.2013.9

    • NAID

      10031177220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390268, KAKENHI-PROJECT-23591229, KAKENHI-PROJECT-23659513, KAKENHI-PROJECT-23791148, KAKENHI-PUBLICLY-24116503, KAKENHI-PROJECT-24659421, KAKENHI-PROJECT-24700951
  • [Journal Article] ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis.2013

    • Author(s)
      Tanaka H.. Shimazawa M., Takata M., Kaneko H., Tsuruma K., Ikeda T., Warita H., Aoki M., Yamada M., Takahashi H., Hozumi I., Minatsu H., Inuzuka T. and Hara H.
    • Journal Title

      Journal of Neurology

      Volume: (Epub ahead of print) Issue: 7 Pages: 1782-1797

    • DOI

      10.1007/s00415-013-6877-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-11J08471, KAKENHI-PROJECT-23240049, KAKENHI-PROJECT-23591229, KAKENHI-PROJECT-23591535, KAKENHI-PROJECT-24591256
  • [Journal Article] ITIH4 and Gpx3 are potential biomarkers for amyotrophic lateral sclerosis2013

    • Author(s)
      Tanaka H, Shimazawa M, Takata M, Kaneko H, Tsuruma K, Ikeda T, Warita H, Aoki M, Yamada M, Takahashi H, Hozumi I, Minatsu H, Inuzuka T, Hara H
    • Journal Title

      J Neurol

      Volume: 260(7) Pages: 1782-1797

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Journal Article] 神経変性と機能保持・回復の神経科学的基盤2013

    • Author(s)
      割田仁
    • Journal Title

      神経治療学

      Volume: 30(6) Pages: 718-721

    • Data Source
      KAKENHI-PROJECT-23591229
  • [Journal Article] ALSに対する再生医療の開発2012

    • Author(s)
      割田仁,青木正志
    • Journal Title

      脳21

      Volume: 15(1) Pages: 57-61

    • Data Source
      KAKENHI-PROJECT-23591229
  • [Journal Article] Involvement of activated microglia in increased vulnerability of motoneurons after facial nerve avulsion in presymptomatic amyotrophic lateral sclerosis model rats2012

    • Author(s)
      Sanagi T, Nakamura Y, Suzuki E, Uchino S, Aoki M, Warita H, Itoyama Y, Kohsaka S, Ohsawa K
    • Journal Title

      Glia

      Volume: 60(5) Pages: 782-793

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Journal Article] FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion.2010

    • Author(s)
      Suzuki N, Aoki M, Warita H, et al
    • Journal Title

      J Hum Genet. 55(4)

      Pages: 252-254

    • NAID

      10030734667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion2010

    • Author(s)
      Suzuki N, Aoki M, Warita H, et al.
    • Journal Title

      J Hum Genet (未定, 印刷中)

    • NAID

      10030734667

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] 長期人工呼吸管理下に気管腕頭動脈瘻からの急性出血で死亡した家族性ALSの1例2008

    • Author(s)
      加藤量広, 鈴木直輝, 青木正志, 割田仁, 神一敬, 糸山泰人
    • Journal Title

      臨床神経学 48(1)

      Pages: 60-62

    • NAID

      10020176147

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] Accumulation of chondroitin sulfate proteoglycans in the microenvironment of spinal motor neurons in amyotrophic lateral sclerosis transeenic rats2008

    • Author(s)
      Mizuno H, Warita H, Aoki M, and Itoyama Y
    • Journal Title

      Journal of Neuroscience Research 86(11)

      Pages: 2512-2523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] 筋萎縮性側索硬化症(ALS)に対する神経再生誘導の試み2008

    • Author(s)
      青木正志, 割田仁, 水野秀紀, 糸山泰人
    • Journal Title

      再生医療 7(4)

      Pages: 366-370

    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] Accumulation of chondroitin sulfate proteoglycans in the microenvironment of spinal motor neurons in amyotrophic lateral sclerosis transgenic rats.2008

    • Author(s)
      Mizuno H, Warita H, Aoki M, Itoyama Y.
    • Journal Title

      J Neurosci Res 86(11)

      Pages: 2512-2523

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] ALSの神経再生医療2008

    • Author(s)
      割田仁, 水野秀紀, 青木正志, 糸山泰人
    • Journal Title

      Clinical Neuroscience 26(3)

      Pages: 303-336

    • Data Source
      KAKENHI-PROJECT-20790609
  • [Journal Article] Upregulation of insulin-like growth factor-II receptor in reactive astrocytes in the spinal cord of amyotrophic lateral sclerosis transeenic rats2008

    • Author(s)
      Dagvajantsan B, Aoki M, Warita H, Suzuki N, Itoyama Y
    • Journal Title

      Tohoku Journal of Experimental Medicine 214(4)

      Pages: 303-310

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Patent] 神経軸索分岐異常の改善2019

    • Inventor(s)
      秋山徹也、鈴木直輝、割田仁、青木正志ら。
    • Industrial Property Rights Holder
      秋山徹也、鈴木直輝、割田仁、青木正志ら。
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-060876
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-18K07519
  • [Presentation] Motor nerve organoid is useful tool to analyze axonal degeneration of ALS.2021

    • Author(s)
      Suzuki N, Kawada J, Akiyama T, Mitsuzawa S, Kato M, Warita H, Fujii T, Eggan K, Okano H, Aoki M.
    • Organizer
      第62回日本神経学会学術大会(62st Annual Meeting of the Japanese Society of Neurology)
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Presentation] Reduced PHOX2B stability causes axonal growth impairment in motor neurons with TARDBP mutations.2021

    • Author(s)
      Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Nishiyama A, Izumi R, Kato M, Warita H, Okano H, Aoki M.
    • Organizer
      PACTALS 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Presentation] Axonal growth impairment in iPS-derived motor neurons with TARDBP mutations.2021

    • Author(s)
      Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Mitsuhashi H, Nishiyama A, Ikeda K, Shijo T, Nakamura N, Ono Y, Ono R, Izumi R, Ohno A, Nakagawa T, Nakayama K, Warita H, Okano H, Aoki M.
    • Organizer
      第62回日本神経学会学術大会(62st Annual Meeting of the Japanese Society of Neurology)
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Presentation] Axonal growth impairment in motor neurons with TARDBP mutations were mediated by PHOX2B downregulation.2021

    • Author(s)
      Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Funayama R, Shirota M, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Kato M, Warita H, Okano H, Aoki M.
    • Organizer
      32th International Symposium on ALS/MND
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Presentation] Reduced PHOX2B stability causes axonal growth impairment in motor neurons with ALS-linked TARDBP mutations.2021

    • Author(s)
      Mitsuzawa S, Suzuki N, Akiyama T, Ishikawa M, Sone T, Kawada J, Mitsuhashi H, Morimoto S, Ikeda K, Shijo T, Ohno A, Nakamura N, Ono H, Ono R, Nishiyama A, Izumi R, Kaneda S, Ikeuchi Y, Nakayama K, Fujii T, Warita H, Okano H, Aoki M.
    • Organizer
      ISSCR 2021 Tokyo
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Presentation] ALSに対する肝細胞増殖因子(HGF)脊髄腔内反復投与の第II相試験2020

    • Author(s)
      割田 仁
    • Organizer
      第61回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K07897
  • [Presentation] BMP4, a bone morphogenetic protein, accelerates disease progression of amyotrophic lateral sclerosis.2019

    • Author(s)
      四條友望,割田 仁,鈴木直輝,池田謙輔,光澤志緒,秋山徹也,小野洋也,西山亜由美,井泉瑠美子,青木正志
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Elucidating axonal pathophysiology under fused in sarcoma (FUS)-mutant ALS motor neurons.2019

    • Author(s)
      秋山徹也,鈴木直輝,石川 充,川田治良,藤井輝夫,藤島史喜,舟山 亮,中山啓子,三橋弘明,割田 仁,岡野栄之,青木正志
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] hnRNPA1変異によるMSP3型の病態解明研究2019

    • Author(s)
      割田 仁
    • Organizer
      第60回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Microvasculature as a pro-inflammatory component in a rat model of ALS.2019

    • Author(s)
      割田 仁,四條友望,池田謙輔,秋山徹也,光澤志緒,中村尚子,小野洋也,西山亜由美,鈴木直輝,青木正志
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Cytoplasmic aggregation involving RNA-binding proteins in spinal cord of ALS model rats2018

    • Author(s)
      割田 仁,四條友望,池田謙輔,秋山徹也,小野洋也,光澤志緒,西山亜由美,井泉瑠美子,鈴木直輝,青木正志
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] 神経疾患の新薬開発・医師主導治験の最前線:ALSに対する肝細胞増殖因子(HGF)2018

    • Author(s)
      割田 仁
    • Organizer
      第59回日本神経学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] 筋萎縮性側索硬化症モデル脊髄のアストロサイトにおける骨形成蛋白質の過剰発現2018

    • Author(s)
      四條 友望,割田 仁,鈴木直輝,池田謙輔,小野洋也,秋山徹也,光澤志緒,西山亜由美,井泉瑠美子,青木正志
    • Organizer
      第17回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] ALS-associated C21ORF2 mutation enhances the autoregulation mechanism of NEK12018

    • Author(s)
      渡辺靖章,中川 直,鈴木直輝,割田 仁,中山啓子,青木正志
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Genotype-phenotype analysis of Japanese familial ALS pedigrees with SOD1 mutations2018

    • Author(s)
      西山亜由美,鈴木直輝,割田 仁,井泉瑠美子,島倉奈緒子,秋山徹也,長名シオン,加藤 昌昭,新堀哲也,青木洋子,青木正志
    • Organizer
      第59回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] 筋萎縮性側索硬化症モデルラットにおけるコンドロイチン硫酸プロテオグリカン受容体の異所性発現2017

    • Author(s)
      四條友望,割田 仁,鈴木直輝,池田謙輔,秋山徹也,小野洋也,光澤志緒,西山亜由美,井泉瑠美子,青木正志
    • Organizer
      第16回日本再生医療学会
    • Place of Presentation
      仙台国際センター(宮城・仙台)
    • Year and Date
      2017-03-07
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] 筋萎縮性側索硬化症ラットモデル脊髄における内在性再生機転2017

    • Author(s)
      割田 仁,四條友望,池田謙輔,小野洋也,秋山徹也,光澤志緒,西山亜由美,井泉瑠美子,鈴木直輝,青木正志
    • Organizer
      第16回日本再生医療学会
    • Place of Presentation
      仙台国際センター(宮城・仙台)
    • Year and Date
      2017-03-07
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Targeted next-generation sequencing in Japanese familial amyotrophic lateral sclerosis reveals differences in the genetic variations across populations2017

    • Author(s)
      Nishiyama A, Niihori T, Warita H, Izumi R, Akiyama T, Kato M, Suzuki N, Aoki Y, Aoki M
    • Organizer
      XXIII World Congress of Neurology, Kyoto, Japan (INTERNATIONAL CONFERENCE CENTER KYOTO)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Novel binding partner of dysferlin is required for plasma-membrane repair2017

    • Author(s)
      Ono H, Suzuki N, Kanno S, Izumi R, Takahashi T, Kitajima Y, Osana S, Akiyama T, Ikeda K, Shijo T, Mitsuzawa S, Warita H, Nagatomi R, Araki N, Yasui A Miyake K, Aoki M
    • Organizer
      22th International Annual Congress of the World Muscle Society, Saint Malo, France (Palais du Grand LArge)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Multicenter questionnaire survey for sporadic inclusion body myositis in Japan.2017

    • Author(s)
      Naoki Suzuki, Madoka Mori-Yoshimura, Satoshi Yamashita, Satoshi Nakano, Ken-ya Murata, Yukie Inamori,Naoko Matsui, En Kimura, Hirofumi Kusaka, Tomoyoshi Kondo, Itsuro Higuchi, Ryuji Kaji, Maki Tateyama,Rumiko Izumi, Hiroya Ono, Masaaki Kato, Hitoshi Warita, Toshiaki Takahashi, Ichizo Nishino and Masashi Aoki
    • Organizer
      World Congress of Neurology 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15474
  • [Presentation] Bone morphogenetic protein 4 is up-regulated in a rat model of amyotrophic lateral sclerosis2017

    • Author(s)
      Shijo T, Warita H, Suzuki N, Ikeda K, Akiyama T, Ono H, Mitsuzawa S, Nishiyama A, Izumi R, Aoki M
    • Organizer
      XXIII World Congress of Neurology, Kyoto, Japan (INTERNATIONAL CONFERENCE CENTER KYOTO)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K09773
  • [Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.2016

    • Author(s)
      Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
    • Organizer
      The 13th International Congress of Human Genetics
    • Place of Presentation
      京都(国立京都国際会館)
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H05318
  • [Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation2016

    • Author(s)
      Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M
    • Organizer
      The 13th International Congress of Human Genetics
    • Place of Presentation
      Kyoto(国立京都国際会館)
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Establishment of in vitro FUS-associated familial amyotrophic lateral sclerosis model using human induced pluripotent stem cells.2016

    • Author(s)
      Ichiyanagi N, Fujimori K, Yano M, Fujisaki C, Sone T, Akiyama T, Okada Y, Akamatsu W, Matsumoto T, Ishikawa M, Nishimoto Y, Ishihara Y, Sakuma T, Yamamoto T, Tsuji H, Suzuki N, Warita H, Aoki M, Okano H.
    • Organizer
      ISSCR 2016 Annual Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.2016

    • Author(s)
      井泉瑠美子,割田 仁,新堀哲也,高橋俊明,竪山真規,鈴木直輝,西山亜由美,城田松之,舟山 亮,中山啓子,三橋里美,西野一三,青木洋子,青木正志
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸(神戸コンベンションセンター)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-16H05318
  • [Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.2016

    • Author(s)
      井泉瑠美子,割田 仁,新堀哲也,高橋俊明,竪山真規,鈴木直輝,西山亜由美,城田松之,舟山 亮,中山啓子,三橋里美,西野一三,青木洋子,青木正志
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫・神戸)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Involvement of endogenous neural precursors in spinal cord of a rat model of ALS.2016

    • Author(s)
      割田 仁,四條友望,池田謙輔,小野洋也,秋山徹也,光澤志緒,西山亜由美,井泉瑠美子,鈴木直輝,青木正志
    • Organizer
      第57回日本神経学会学術大会
    • Place of Presentation
      神戸コンベンションセンター(兵庫・神戸)
    • Year and Date
      2016-05-18
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Isolated inclusion body myopathy caused by a multisystem proteinopathy-linked hnRNPA1 mutation.2016

    • Author(s)
      Izumi R, Warita H, Niihori T, Takahashi T, Tateyama M, Suzuki N, Nishiyama A, Shirota M, Funayama R, Nakayama K, Mitsuhashi S, Nishino I, Aoki Y, Aoki M.
    • Organizer
      The 13th International Congress of Human Genetics
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Pericytogenesis in spinal cord microvasculature of a rat model of ALS2015

    • Author(s)
      割田 仁,四條友望,池田謙輔,小野洋也,秋山徹也,西山亜由美,井泉瑠美子,鈴木直輝,加藤昌昭,青木正志
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Genotype-phenotype correlation with FUS/TLS-linked familial ALS cases in Japan2015

    • Author(s)
      秋山徹也,鈴木直輝,割田 仁,加藤昌昭,西山亜由美,井泉瑠美子,池田謙輔,小野洋也,四條友望,青木正志
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] 系統的運動ニューロン変性モデル脊髄における微小血管壁細胞増殖2015

    • Author(s)
      割田 仁,四條友望,池田謙輔,小野洋也,秋山徹也,鈴木直輝,青木正志
    • Organizer
      第38回日本神経科学大会
    • Place of Presentation
      神戸(神戸国際会議場)
    • Year and Date
      2015-07-28
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Chondroitin sulfate proteoglycan receptors in an ALS rat model2015

    • Author(s)
      四條友望,割田 仁,鈴木直輝,池田謙輔,秋山徹也,小野洋也,加藤昌昭,青木正志
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] Comprehensive targeted resequencing analysis in Japanese ALS patients2015

    • Author(s)
      西山亜由美,加藤昌昭,新堀哲也,鈴木直輝,割田 仁,井泉瑠美子,青木洋子,青木正志
    • Organizer
      第56回日本神経学会学術大会
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2015-05-20
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] 変異SOD1による神経変性モデル脊髄における微小血管壁細胞2013

    • Author(s)
      割田仁、水野秀紀、加藤昌昭、鈴木直輝、青木正志
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 変異SOD1によるラット神経変性モデル脊髄における微小血管壁細胞2013

    • Author(s)
      割田 仁,水野秀紀,加藤昌昭,鈴木直輝,青木正志
    • Organizer
      第36回日本神経科学大会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 筋萎縮性側索硬化症モデルラット微小血管の壁細胞を標的とした運動ニューロン保護2013

    • Author(s)
      割田仁、水野秀紀、加藤昌昭、鈴木直輝、青木正志
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 東北大学における家族性ALS遺伝子検査の検討2013

    • Author(s)
      加藤昌昭,割田 仁,井泉瑠美子,島倉奈緒子,安藤里紗,鈴木直輝,青木正志
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25293199
  • [Presentation] 筋萎縮性側索硬化症モデルラット微小血管の壁細胞を標的とした運動ニューロン保護2013

    • Author(s)
      割田 仁,水野秀紀,加藤昌昭,鈴木直輝,青木正志
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25293199
  • [Presentation] 東北大学における家族性ALS遺伝子検査の検討2013

    • Author(s)
      加藤昌昭、割田仁、井泉瑠美子、島倉奈緒子、安藤里紗、鈴木直輝、青木正志
    • Organizer
      第54回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 筋萎縮性側索硬化症モデルラット新生グリア細胞が形成する脊髄微小環境2012

    • Author(s)
      割田仁、加藤昌昭、鈴木直輝、水野秀紀、青木正志
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] Phenotypically transformed glial cells accumulate in adult spinal cords of transgenic rats with motor neuron degeneration2012

    • Author(s)
      Warita H, Mizuno H, Suzuki N, Itoyama Y, Aoki M
    • Organizer
      10th Annual Meeting of the International Society for Stem Cell Research
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] アカデミア発の創薬:ALSに対するHGF2012

    • Author(s)
      割田仁
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] Phenotypically transformed glial cells accumulate in adult spinal cords of transgenic rats with motor neuron degeneration.2012

    • Author(s)
      Warita H, Mizuno H, Suzuki N, Itoyama Y, Aoki M
    • Organizer
      10th Annual Meeting of the International Society for Stem Cell Research
    • Place of Presentation
      Yokohama
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] アカデミア発の創薬: ALSに対するHGF2012

    • Author(s)
      割田 仁
    • Organizer
      第53回日本神経学会学術大会
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 運動ニューロン疾患モデル脊髄における増殖性グリア細胞の形質変化2012

    • Author(s)
      割田仁、水野秀紀、加藤昌昭、鈴木直輝、青木正志
    • Organizer
      第35回日本神経科学大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 筋萎縮性側索硬化症モデルラットにおける骨格筋再生2011

    • Author(s)
      割田仁、水野秀紀、鈴木直輝、糸山泰人、青木正志
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] Adult Skeletal Myogenesis in a Rat Model of Amyotrophic Lateral Sclerosis.2011

    • Author(s)
      Warita H, Mizuno H, Suzuki N, Itoyama Y, Aoki M
    • Organizer
      9th Annual Meeting of the International Society for Stem Cell Research
    • Place of Presentation
      Toronto, Canada
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] Adult skeletal myogenesis in a rat model of amyotrophic lateral sclerosis2011

    • Author(s)
      Warita H, Mizuno H, Suzuki N, Itoyama Y, Aoki M
    • Organizer
      9th Annual Meeting of the International Society for Stem Cell Research
    • Place of Presentation
      トロント、カナダ
    • Data Source
      KAKENHI-PROJECT-23591229
  • [Presentation] 筋萎縮性側索硬化症モデルラット脊髄における微小血管新生2010

    • Author(s)
      割田仁, 青木正志, 水野秀紀, 鈴木直輝, 船越洋, 中村敏一, 糸山泰人
    • Organizer
      第9回日本再生医療学会
    • Place of Presentation
      広島
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] ALSモデルラット脊髄活性化アストロサイトにおける再生阻害因子発現2009

    • Author(s)
      水野秀紀, 割田仁, 青木正志, ら
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] 逐次的な再生誘導因子投与によるALSモデルラット脊髄の内在性再生機転促進2009

    • Author(s)
      割田仁, 青木正志, 水野秀紀, ら
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Endothelial proliferation in the spinal cord microvasculature of ALS transgenic rats2009

    • Author(s)
      割田仁, 青木正志, 水野秀紀, et al.
    • Organizer
      14th International Congress of the World Muscle Society
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Appearance of phagocytic microglia adjacent to motoneurons in the spinal cord of presymptomatic ALS model rats2009

    • Author(s)
      佐柳友規, 大澤圭子, 湯浅茂樹, 鈴木恵里, 青木正志, 割田仁, 糸山泰人, 高坂新一
    • Organizer
      第32回日本分子生物学会年会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] 若年発症・急速進行・好塩基性封入体を特徴としFUS/TLSに変異を持つ日本人家族性筋萎縮性側索硬化症の3家系2009

    • Author(s)
      鈴木直輝, 青木正志, 割田仁, ら
    • Organizer
      日本人類遺伝学会第54回大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] ALSモデルラットにおける顔面神経損傷後のミクログリアの挙動の解析2009

    • Author(s)
      佐柳友規, 中村泰子, 青木正志, 割田仁, 糸山泰人, 湯浅茂樹, 高坂新一, 大澤圭子
    • Organizer
      Neuroscience 2009〔第32回日本神経科学大会〕
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] 筋萎縮性側索硬化症マウスに対する一酸化窒素合成酵素阻害剤による治療の検討2009

    • Author(s)
      鈴木直輝, 青木正志, 割田仁, 水野秀紀, 武田伸一, 糸山泰人
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Endothelial Proliferation in the spinal cord microvasculature of ALS transgenic rats.2009

    • Author(s)
      Warita H, Aoki M, Mizuno H, Itoyama Y.
    • Organizer
      20th International Symposium on ALS/MND
    • Place of Presentation
      Berlin, Germany
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] 逐次的な再生誘導因子投与によるALSモデルラット脊髄の内在性再生機転促進2009

    • Author(s)
      割田仁, 青木正志, 船越洋, 中村敏一, 糸山泰人
    • Organizer
      Neuroscience 2009〔第32回日本神経科学大会〕
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Dislocation of neuronal nitric oxide synthase contributes to muscle atrophy in amyotrophic lateral sclerosis2009

    • Author(s)
      鈴木直輝, 青木正志, 割田仁, et al.
    • Organizer
      14th International Congress of the World Muscle Society
    • Place of Presentation
      Geneva, Switzerland
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] 運動ニューロン変性を示すラットモデル脊髄における微小血管新生. Neuroscience 20092009

    • Author(s)
      割田仁, 青木正志, 船越洋, ら
    • Organizer
      第32回日本神経科学大会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] 神経栄養因子によるALSの治療戦略2009

    • Author(s)
      青木正志, 割田仁, 糸山泰人
    • Organizer
      第50回日本神経学会総会(シンポジウム)
    • Place of Presentation
      仙台
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Digestion of the extracellular chondroitin sulfate promotes an intrinsic regenerative process in the spinal cord of ALS transgenicrats2008

    • Author(s)
      Warita H, Mizuno H, Aoki M, Itoyama Y
    • Organizer
      19th International Svmnosium on ALS/MND
    • Place of Presentation
      Birmingham. UK
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Digestion of the extracellular chondroitin sulfate promotes an intrinsic regenerative process in the spinal cord of ALS transgenic rats.2008

    • Author(s)
      Warita H, Mizuno H, Aoki M, Itoyama Y.
    • Organizer
      19th International Symposium on ALS/MND
    • Place of Presentation
      Birmingham, UK
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Effects of Edaravone, a free radical scavenger approved in Japan for indications of acute ischemic stroke, in a transgenic rat model of amvotronhic lateral sclerosis2008

    • Author(s)
      Aoki M, Warita H, Mizuno H, Yuki S, Takahashi I, Itoyama Y
    • Organizer
      19th International Svmnosium on ALS/MND
    • Place of Presentation
      Birmingham. UK
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] Effects of Edaravone, a free radical scavenger approved in Japan for indications of acute ischemic stroke, in a transgenic rat model of amyotrophic lateral sclerosis.2008

    • Author(s)
      Aoki M, Warita H, Mizuno H, et al.
    • Organizer
      19th International Symposium on ALS/MND
    • Place of Presentation
      Birmingham, UK
    • Data Source
      KAKENHI-PROJECT-20790609
  • [Presentation] ALSモデルラット髄腔内へのコンドロイチン分解酵素持続投与2007

    • Author(s)
      割田 仁, ら
    • Organizer
      第48回日本神経学会総会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-18790586
  • [Presentation] 成体ラット運動ニューロン変性モデル脊髄における潜在的再生能

    • Author(s)
      割田 仁
    • Organizer
      第37回日本神経科学学会大会
    • Place of Presentation
      横浜(パシフィコ横浜)
    • Year and Date
      2014-09-11 – 2014-09-13
    • Data Source
      KAKENHI-PROJECT-26461288
  • [Presentation] 筋萎縮性側索硬化症モデル成体脊髄における潜在的neurogenic niche

    • Author(s)
      割田 仁
    • Organizer
      第55回日本神経学会学術大会
    • Place of Presentation
      福岡(福岡国際会議場)
    • Year and Date
      2014-05-21 – 2014-05-24
    • Data Source
      KAKENHI-PROJECT-26461288
  • []

  • 1.  Naoki SUZUKI (70451599)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 22 results
  • 2.  Aoki Masashi (70302148)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 22 results
  • 3.  Kato MASAAKI (50622479)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 4.  OKANO Hideyuki (60160694)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  NIIHORI Tetsuya
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  YAMASHITA Satoshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  中川 直
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  松原 洋一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  漆谷 真
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  曽根 岳史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  郭 伸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  相澤 仁志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  荒木 伸一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  三須 建郎
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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