Azuma Koutaro 東浩太郎

… Alternative Names

Azuma Kotaro 東浩太郎

AZUMA Kotaro 東浩太郎

東浩太郎アズマコウタロウ

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Researcher Number	30401110
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 医学部附属病院, 講師 2017 – 2020: 地方独立行政法人東京都健康長寿医療センター(東京都健康長寿医療センター研究所), 東京都健康長寿医療センター研究所, 研究員 2011 – 2013: 東京大学, 医学部附属病院, 特任講師 2010: 東京大学, 医学部附属病院, 助教 2007: The University of Tokyo, 医学部・附属病院, 医員 2006: 東京大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / Medium-sized Section 52:General internal medicine and related fields / General surgery / General medical chemistry / Biological Sciences / Endocrinology / Pathological medical chemistry
Keywords	Principal Investigator TRIM47 / 乳がん / 乳癌 / スフェロイド培養 / ユビキチン化 / TRIMファミリー / TRIM39 / TRIM44 / TRIM25 / 治療抵抗性 … More / ビタミンK / エストロゲン受容体 / 核内受容体 / 蛋白質修飾 / フレイル / PDC/PDXモデル / オートファジー / 三次元スフェロイド培養 / 治療標的 / バイオマーカー / NFkappaBシグナル / NF-kappaBシグナル / ホルモン療法耐性 / 蛋白質 / 遺伝子 / 老化 / 核内作用 / 核外作用 / 次世代シーケンサー / 核外受容体 / 認知症 / 骨粗鬆症 / nongenomic action / 脱アセチル化酵素 / アセチル化 / エストロゲン Less

高齢者の認知機能・フレイルと関連するビタミンKによる新規蛋白質修飾の解明Principal Investigator
- Principal Investigator
  
  東浩太郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  The University of Tokyo
TRIM47関連蛋白質を標的としポストゲノム診療を見据えた乳癌個別化医療の探索Principal Investigator
- Principal Investigator
  
  東浩太郎
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The University of Tokyo
Development of treatment strategy targeting mechanisms mediated by TRIM family proteinsPrincipal Investigator
- Principal Investigator
  
  Azuma Kotaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  The University of Tokyo
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Investigation on the breast cancer-promoting effects of TRIM family proteins and its clinical applicationPrincipal Investigator
- Principal Investigator
  
  Azuma Kotaro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology
Analysis of vitamin K functions on age-related diseases using organ-specific gene knockout mice.Principal Investigator
- Principal Investigator
  
  AZUMA Kotaro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  The University of Tokyo
ホルモン依存性の性差を生み出すエストロゲン受容体核内・核外作用機構の総合的解明Principal Investigator
- Principal Investigator
  
  東浩太郎
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Analysis and treatment-application of novel nongenomic action of estrogen receptor mediated by protein deacetylationPrincipal Investigator
- Principal Investigator
  
  AZUMA Kotaro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  The University of Tokyo
エストロゲン受容体の核外作用を介したアセチル化の制御とシグナル伝達機構の解明Principal Investigator
- Principal Investigator
  
  東浩太郎
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Pathological medical chemistry
- Research Institution
  The University of Tokyo

[Book] Vitamin K, SXR, and GGCX2017
- Author(s)
  Azuma Kotaro、Inoue Satoshi
- Total Pages
  12
- Publisher
  InTech
- ISBN
  9789535130208
- Data Source
  KAKENHI-PROJECT-17K10571
[Book] Nongenomic action of estrogen receptor in breast cancer. Estrogen Receptors: Mechanisms, Structure and Role in Disease2012
- Author(s)
  Azuma K
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PUBLICLY-23132506
[Journal Article] EBAG9-deficient mice display decreased bone mineral density with suppressed autophagy2024
- Author(s)
  Azuma Kotaro、Ikeda Kazuhiro、Shiba Sachiko、Sato Wataru、Horie Kuniko、Hasegawa Tomoka、Amizuka Norio、Tanaka Shinya、Inoue Satoshi
- Journal Title
  
  iScience
  
  Volume: 27 Issue: 2 Pages: 108871-108871
- DOI
  10.1016/j.isci.2024.108871
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06929, KAKENHI-PROJECT-23K07996, KAKENHI-PROJECT-22K19572, KAKENHI-PROJECT-21H04829, KAKENHI-PROJECT-21H02981, KAKENHI-PROJECT-23K27653, KAKENHI-PROJECT-23K27657
[Journal Article] Efp/TRIM25 and Its Related Protein, TRIM47, in Hormone-Dependent Cancers2022
- Author(s)
  Azuma Kotaro、Inoue Satoshi
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 15 Pages: 2464-2464
- DOI
  10.3390/cells11152464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08945
[Journal Article] TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer2021
- Author(s)
  Azuma Kotaro、Ikeda Kazuhiro、Suzuki Takashi、Aogi Kenjiro、Horie-Inoue Kuniko、Inoue Satoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 118 Issue: 35
- DOI
  10.1073/pnas.2100784118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K21636, KAKENHI-PROJECT-20K21667, KAKENHI-PROJECT-21H04829, KAKENHI-PROJECT-20H03734, KAKENHI-PROJECT-21H02981, KAKENHI-PROJECT-20K08945
[Journal Article] OCT1 Is a Poor Prognostic Factor for Breast Cancer Patients and Promotes Cell Proliferation via Inducing NCAPH2021
- Author(s)
  Ogura Takuya、Azuma Kotaro、Sato Junichiro、Kinowaki Keiichi、Takayama Ken-Ichi、Takeiwa Toshihiko、Kawabata Hidetaka、Inoue Satoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 21 Pages: 11505-11505
- DOI
  10.3390/ijms222111505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07350, KAKENHI-PROJECT-20K08945
[Journal Article] TRIM39 is a poor prognostic factor for patients with estrogen receptor‐positive breast cancer and promotes cell cycle progression2021
- Author(s)
  Ogura Takuya、Azuma Kotaro、Takeiwa Toshihiko、Sato Junichiro、Kinowaki Keiichi、Ikeda Kazuhiro、Kawabata Hidetaka、Inoue Satoshi
- Journal Title
  
  Pathology International
  
  Volume: 72 Issue: 2 Pages: 96-106
- DOI
  10.1111/pin.13190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K21636, KAKENHI-PROJECT-21H02981, KAKENHI-PROJECT-20K08945
[Journal Article] Combined use of immunoreactivities of RIG-I with Efp/TRIM25 for predicting prognosis of estrogen receptor-positive breast cancer patients.2021
- Author(s)
  Sato J, Azuma K, Kinowaki K, Ikeda K, Ogura T, Takazawa Y, Kawabata H, Kitagawa M, Inoue S.
- Journal Title
  
  Clin Breast Cancer
  
  Volume: - Issue: 5 Pages: 30328-1
- DOI
  10.1016/j.clbc.2020.12.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08945, KAKENHI-PROJECT-20K21636, KAKENHI-PROJECT-21H02981
[Journal Article] Combined A20 and tripartite motif-containing 44 as poor prognostic factors for breast cancer patients of the Japanese population.2021
- Author(s)
  Sato J, Azuma K, Kinowaki K, Ikeda J, Ogura T, Takazawa Y, Kawabata H, Kitagawa M, Inoue S.
- Journal Title
  
  Pathol Int
  
  Volume: 71 Issue: 1 Pages: 60-69
- DOI
  10.1111/pin.13047
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08945, KAKENHI-PROJECT-20K21636
[Journal Article] TRIM44 promotes cell proliferation and migration by inhibiting FRK in renal cell carcinoma2020
- Author(s)
  Yamada Yuta、Kimura Naoki、Takayama Ken‐ichi、Sato Yusuke、Suzuki Takashi、Azuma Kotaro、Fujimura Tetsuya、Ikeda Kazuhiro、Kume Haruki、Inoue Satoshi
- Journal Title
  
  Cancer Science
  
  Volume: 111 Issue: 3 Pages: 881-890
- DOI
  10.1111/cas.14295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H04334, KAKENHI-PROJECT-17K10571, KAKENHI-PROJECT-19K09065, KAKENHI-PROJECT-20K07350
[Journal Article] TRIM44 Is a Poor Prognostic Factor for Breast Cancer Patients as a Modulator of NF-κB Signaling2017
- Author(s)
  Kawabata Hidetaka、Azuma Kotaro、Ikeda Kazuhiro、Sugitani Ikuko、Kinowaki Keiichi、Fujii Takeshi、Osaki Akihiko、Saeki Toshiaki、Horie-Inoue Kuniko、Inoue Satoshi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 18 Issue: 9 Pages: 1931-1931
- DOI
  10.3390/ijms18091931
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10571, KAKENHI-PROJECT-17H04205, KAKENHI-PROJECT-16K15496
[Journal Article] Vitamin K: novel molecular mechanisms of action and its roles in osteoporosis2014
- Author(s)
  Azuma K, Ouchi Y, Inoue S
- Journal Title
  
  Geriatric Gerontol Int
  
  Volume: 14 Issue: 1 Pages: 1-7
- DOI
  10.1111/ggi.12060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-24659126, KAKENHI-PROJECT-24790273
[Journal Article] Liver-specific γ-glutamyl carboxylase-1 deficient mice display bleeding diathesis and short life span.2014
- Author(s)
  Azuma K, Tsukui T, Ikeda K, Shiba S, Nakagawa K, Okano T, Urano T, Horie-Inoue K, Ouchi Y, Ikawa M, Inoue S
- Journal Title
  
  PLoS ONE
  
  Volume: 9 Issue: 2 Pages: e88643-e88643
- DOI
  10.1371/journal.pone.0088643
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-23390022, KAKENHI-PROJECT-24659126, KAKENHI-PROJECT-24790273, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-25293214
[Journal Article] Genomic and non-genomic actions of estrogen: Recent developments.2012
- Author(s)
  Azuma K
- Journal Title
  
  BioMol Concepts
  
  Volume: 3 Issue: 4 Pages: 365-370
- DOI
  10.1515/bmc-2012-0002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23249040, KAKENHI-PUBLICLY-23132506
[Journal Article] Clinical significance of steroid and xenobiotic receptor(SXR) and its targeted gene CYP3A4 in human prostate cancer2012
- Author(s)
  Fujimura T, Takahashi S, Urano T, Tanaka T, Zhang W, Azuma K, Takayama K, Obinata D, Murata T, Horie-Inoue K, Kodama T, Ouchi Y, Homma Y, Inoue S
- Journal Title
  
  Cancer Sci
  
  Volume: 103 Issue: 2 Pages: 176-180
- DOI
  10.1111/j.1349-7006.2011.02143.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591170, KAKENHI-PROJECT-22790882, KAKENHI-PUBLICLY-23117508, KAKENHI-PUBLICLY-23132506, KAKENHI-PROJECT-23249040, KAKENHI-PROJECT-23791049, KAKENHI-PROJECT-221S0001
[Journal Article] PROX1 suppresses vitamin K-induced transcriptional activity of steroid and xenobiotic receptor2011
- Author(s)
  Azuma K, Urano T, Watabe T, Ouchi Y, Inoue S
- Journal Title
  
  Genes Cells
  
  Volume: 16 Issue: 11 Pages: 1063-1070
- DOI
  10.1111/j.1365-2443.2011.01551.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591170, KAKENHI-PROJECT-22790882, KAKENHI-PUBLICLY-23117508, KAKENHI-PUBLICLY-23132506, KAKENHI-PROJECT-23249040
[Journal Article] Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone resorption2010
- Author(s)
  Azuma K, Casey SC, Ito M, Urano T, Horie K, Ouchi Y, Kirchner S, Blumberg B, Inoue S
- Journal Title
  
  J Endocrinol
  
  Volume: 207 Issue: 3 Pages: 257-263
- DOI
  10.1677/joe-10-0208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591170, KAKENHI-PROJECT-22790882
[Journal Article] Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone resorption.2010
- Author(s)
  Azuma K, Casey SC, Inoue S, et.al.
- Journal Title
  
  J Endocrinol
  
  Volume: 207 Pages: 257-263
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790882
[Journal Article] Genomic and non-genomic actions of estrogen : recent developments
- Author(s)
  Azuma K, Inoue S
- Journal Title
  
  BioMol Concepts
  
  Volume: (Review)(in press)
- Data Source
  KAKENHI-PROJECT-22790882
[Journal Article] Genomic and non-genomic actions of estrogen : recent developments. Review
- Author(s)
  Azuma K, Inoue S
- Journal Title
  
  BioMol Concepts
  
  Volume: (in press)
- Data Source
  KAKENHI-PUBLICLY-23132506
[Journal Article] Genomic andnon-genomic actions of estrogen : Recentdevelopments
- Author(s)
  Azuma K, Inoue S
- Journal Title
  
  BioMol Concepts
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Effect on autophagy and bone metabolism of estrogen receptor-binding fragment associated antigen 9 (EBAG9)2023
- Author(s)
  Azuma K, Ikeda K, Horie K, Inoue S
- Organizer
  IAGG Asia/Oceania Regional Congress 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27657
[Presentation] TRIM39はER陽性乳がん患者の予後不良因子であり乳がん細胞の細胞周期の進行を促進する2023
- Author(s)
  小倉拓也、東浩太郎、竹岩俊彦、佐藤順一朗、木脇圭一、池田和博、川端英孝、井上聡
- Organizer
  第31回　日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-23K27657
[Presentation] EBAG9（estrogen receptor-binding fragment associated antigen 9）による骨代謝およびオートファジー制御2023
- Author(s)
  東浩太郎、井上聡
- Organizer
  第46回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K27657
[Presentation] OCT1は乳がん患者の予後不良因子でありNCAPHを誘導し乳がん細胞の増殖を亢進する2022
- Author(s)
  小倉拓也、東浩太郎、佐藤順一朗、木脇圭一、高山賢一、竹岩俊彦、川端英孝、井上聡
- Organizer
  第30回　日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08945
[Presentation] Prediction of endocrine resistance of breast cancer based on combined immunoreactivity study for TRIM47 and NR4A12022
- Author(s)
  Kotaro Azuma, Kazuhiro Ikeda, Takashi Suzuki, Kuniko Horie, Satoshi Inoue
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08945
[Presentation] ER陽性乳癌におけるRetinoic acid-inducible gene IおよびA20発現の免疫組織化学解析2021
- Author(s)
  佐藤順一朗、東浩太郎、木脇圭一、小倉拓也、池田和博、北川昌伸、川端英孝、井上聡
- Organizer
  第28回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08945
[Presentation] TRIM47 contributes to tamoxifen resistance of breast cancer via stabilizing PKCepsilon2021
- Author(s)
  Kotaro Azuma, Kazuhiro Ikeda, Takashi Suzuki, Kuniko Horie, Satoshi Inoue
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K08945
[Presentation] 乳がん内分泌療法に対する耐性予測因子TRIM47によるNF-κBシグナル活性化2021
- Author(s)
  東浩太郎、池田和博、鈴木貴、堀江公仁子、井上聡
- Organizer
  第93回日本内分泌学会
- Data Source
  KAKENHI-PROJECT-20K08945
[Presentation] Combined A20 and TRIM44 as poor prognostic factors for breast cancer patients of the Japanese population2021
- Author(s)
  佐藤順一朗、東浩太郎、木脇圭一、池田和博、小倉拓也、髙澤豊、川端英孝、北川昌伸、井上聡
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-20K08945
[Presentation] 乳がんにおける新規タモキシフェン耐性予測因子TRIM47のNF-kappaBシグナル活性化メカニズム2019
- Author(s)
  東浩太郎、池田和博、鈴木貴、堀江公仁子、井上聡
- Organizer
  第20回ホルモンと癌研究会
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] TRIM39 is a poor prognostic factor for breast cancer patients and promotes proliferation and migration of breast cancer cells.2019
- Author(s)
  Ogura T, Azuma K, Sato J, Kinowaki K, Ikeda K, Kawabata H, Inoue S.
- Organizer
  San Antonio Breast Cancer Symposium 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] 乳癌におけるRetinoic acid-inducible gene I (RIG-I)蛋白質の免疫組織化学的な発現解析2019
- Author(s)
  佐藤順一朗、東浩太郎、木脇圭一、小倉拓也、池田和博、藤井丈士、北川昌伸、川端英孝、井上聡
- Organizer
  第27回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] 乳癌の悪性化に関わるTRIM44の標的因子の探索と同定2018
- Author(s)
  川端英孝、東浩太郎、池田和博、杉谷郁子、木脇圭一、藤井丈士、大崎昭彦、佐伯俊昭、堀江公仁子、井上聡
- Organizer
  第26回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] Expression of TRIM44 in breast cancer is a novel prognostic factor affecting cellular growth and motility2017
- Author(s)
  Kawabata Hidetaka、Azuma Kotaro、Ikeda Kazuhiro、Sugitani Ikuko、Kinowaki Keiichi、Fujii Takeshi、Osaki Akihiko、Saeki Toshiaki、Horie-Inoue Kuniko、Inoue Satoshi
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] TRIM47の乳がんにおける新規予後マーカーとしての役割とそのメカニズム2017
- Author(s)
  東浩太郎、井上聡
- Organizer
  TOBIRA第6回研究交流フォーラム
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] TRIM44 is a possible poor prognostic factor for breast cancer patients and positively regulates NF-kB signaling pathway2017
- Author(s)
  Kawabata Hidetaka、Azuma Kotaro、Ikeda Kazuhiro、Sugitani Ikuko、Kinowaki Keiichi、Fujii Takeshi、Osaki Akihiko、Saeki Toshiaki、Horie-Inoue Kuniko、Inoue Satoshi
- Organizer
  San Antonio Breast Cancer Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] 乳がんに対するホルモン療法耐性予測因子TRIM47の作用メカニズム2017
- Author(s)
  東浩太郎、池田和博、井上聡
- Organizer
  首都大バイオコンファレンス 2017
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] Increased expression of TRIM 47 as a novel prognostic factor related to tamoxifen resistance of breast cancer patients2017
- Author(s)
  Azuma Kotaro、Ikeda Kazuhiro、Takashi Suzuki, Osaki Akihiko、Saeki Toshiaki、Horie Kuniko、Inoue Satoshi
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K10571
[Presentation] [シンポジウム] ビタミンKの骨関節に対するアンチエイジング効果2013
- Author(s)
  東浩太郎、大内尉義、井上聡
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation]2013
- Author(s)
  東浩太郎, 大内尉義, 井上聡
- Organizer
  [シンポジウム] ビタミンKの骨関節に対するアンチエイジング効果
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] 次世代シーケンサーによるヒト骨芽細胞系におけるステロイドX受容体標的遺伝子の解析2013
- Author(s)
  堀江公仁子, 東浩太郎, 大石貴史, 池田和博, 井上聡
- Organizer
  第11回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] 核内受容体SXR/ PXRを介するビタミンKの関節軟骨に対する作用2013
- Author(s)
  東浩太郎, Stephanie Casey, 浦野友彦, 大内尉義, Bruce Blumberg, 井上聡
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] Comprehensive Analysis of Transcriptional Regulation by Steroid and Xenobiotic Receptor in Osteoblastic Cells Using RNA-Sequencing2013
- Author(s)
  Azuma K, Urano T, Ouchi Y, Inoue S
- Organizer
  The Endocrine Society's 95^<th> annual meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] 核内受容体SXR/PXRを介するビタミンKの関節軟骨に対する作用2013
- Author(s)
  東浩太郎、Stephanie Casey、浦野友彦、大内尉義、Bruce Blumberg、井上聡
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] 加齢性疾患におけるビタミンKの新しい作用メカニズムとその臨床応用2013
- Author(s)
  東浩太郎
- Organizer
  第55回日本老年医学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] Comprehensive Analysis of Transcriptional Regulation by Steroid and Xenobiotic Receptor in Osteoblastic Cells Using RNA-Sequencing.2013
- Author(s)
  Azuma K, Urano T, Ouchi Y, Inoue S
- Organizer
  The Endocrine Society’s 95th annual meeting
- Place of Presentation
  San Francisco, CA, USA
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] [カレントコンセプト] 核内受容体SXR/PXRを介するビタミンKの骨関節保護作用2012
- Author(s)
  東浩太郎、浦野友彦、大内尉義、井上聡
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] 骨粗鬆症薬ビタミンKの作用を担うγカルボキシラーゼの骨芽細胞における役割2012
- Author(s)
  東浩太郎, 柴祥子, 池田和博, 浦野友彦, 堀江公仁子, 大内尉義, 井上聡
- Organizer
  第54回日本老年医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] ビタミンKがリガンドとなるSXR/PXRの骨軟骨代謝における役割2012
- Author(s)
  東浩太郎、大内尉義、井上聡
- Organizer
  第12回東京骨関節フォーラム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] [シンポジウム] ビタミンKによる骨代謝調節2012
- Author(s)
  東浩太郎, 大内尉義, 井上聡
- Organizer
  第10回日本機能性食品医用学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] ビタミンKがリガンドとなるSXR/ PXRの骨軟骨代謝における役割2012
- Author(s)
  東浩太郎, 大内尉義, 井上聡
- Organizer
  第12回東京骨関節フォーラム
- Place of Presentation
  東京
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] [シンポジウム] ビタミンKによる骨代謝調節（東京）2012
- Author(s)
  東浩太郎、大内尉義、井上聡
- Organizer
  第10回日本機能性食品医用学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] 骨芽細胞におけるエストロゲン応答遺伝子の解析2012
- Author(s)
  東浩太郎
- Organizer
  第8回SERM学術研究会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] [カレントコンセプト] 核内受容体SXR/ PXRを介するビタミンKの骨関節保護作用2012
- Author(s)
  東浩太郎, 浦野友彦, 大内尉義, 井上聡
- Organizer
  第30回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24790273
[Presentation] マイクロアレイおよび次世代シークエンサーを用いた骨芽細胞におけるエストロゲン応答遺伝子の解析2012
- Author(s)
  東浩太郎
- Organizer
  第12回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-22
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] ビタミンKをリガンドとする核内受容体SXR/PXRの関節軟骨に対するアンチエイジング作用2011
- Author(s)
  東浩太郎、Stephanie Casey、浦野友彦、大内尉義、Bruce Blumberg、井上聡
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都(優秀演題賞(プレナリーセッション)受賞)
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] Novel function of vitamin K on age-related bone and cartilage diseases2011
- Author(s)
  Azuma K, Urano T, Horie K, Ouchi Y, Inoue S
- Organizer
  9th Asia/Oceania Congress of Geriatrics and Gerontology
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Estrogen receptor alpha knockout mice display osteoarthritis-like phenotype2011
- Author(s)
  Azuma K, Ikeda K, Urano T, Ouchi Y, Inoue S
- Organizer
  3^<rd> Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society(ECTS/IBMS)
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Novel function of vitamin K on age-related bone and cartilage diseases2011
- Author(s)
  Azuma K, Urano T, Horie K, Ouchi Y, InoueS
- Organizer
  9th Asia/Oceania Congressof Geriatrics and Gerontology
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Novel transcriptional and post-transcriptional effects of estrogen receptor at plasma membrane2011
- Author(s)
  Azuma K, Urano T, Ouchi Y, Inoue S
- Organizer
  New Horizon in Cancer Research, AACR Intemational Conference
- Place of Presentation
  Delhi, India
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] [優秀演題賞(プレナリーセッション)受賞]ビタミンKをリガンドとする核内受容体SXR/PXRの関節軟骨に対するアンチエイジング作用2011
- Author(s)
  東浩太郎、Stephanie Casey、浦野友彦、大内尉義、Bruce Blumberg、井上聡
- Organizer
  第11回日本抗加齢医学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] 骨芽細胞および骨髄ストローマ細胞におけるエストロゲン応答遺伝子の解析2011
- Author(s)
  東浩太郎、池田和博、浦野友彦、大内尉義、井上聡
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Novel function of vitamin K on age-related bone and cartilage diseases2011
- Author(s)
  Azuma K, Urano T, Horie K, Ouchi Y, Inoue S
- Organizer
  9th Asia/Oceania Congress of Geriatrics and Gerontology
- Place of Presentation
  Melbourne, Australia
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] 骨芽細胞および骨髄ストローマ細胞におけるエストロゲン応答遺伝子の解析2011
- Author(s)
  東浩太郎、池田和博、浦野友彦、大内尉義、井上聡
- Organizer
  第53回日本老年医学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] 骨軟骨における新規エストロゲン応答遺伝子の探索2011
- Author(s)
  東浩太郎、池田和博、浦野友彦、大内尉義、井上聡
- Organizer
  第13回日本骨粗鬆症学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] 骨軟骨における新規エストロゲン応答遺伝子の探索2011
- Author(s)
  東浩太郎、池田和博、浦野友彦、大内尉義、井上聡
- Organizer
  第13回日本骨粗鬆症学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Estrogen receptor alpha knockout mice display osteoarthritis-like phenotype2011
- Author(s)
  Azuma K, Ikeda K, Urano T, Ouchi Y, Inoue S
- Organizer
  3^<rd> Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society (ECTS/IBMS)
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PUBLICLY-23132506
[Presentation] Estrogen receptor alpha knockout mice display osteoarthritis-like phenotype2011
- Author(s)
  Azuma K, Ikeda K, Urano T, Ouchi Y, Inoue S
- Organizer
  3^<rd> Joint Meeting of the European Calcified Tissue Society & the International Bone and Mineral Society (ECTS/IBMS)
- Place of Presentation
  Athens, Greece
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Novel transcriptional and post-transcriptional effects of estrogen receptor at plasma membrane2011
- Author(s)
  Azuma K, Urano T, Ouchi Y, Inoue S
- Organizer
  New Horizon in Cancer Research, AACR International Conference
- Place of Presentation
  Delhi, India
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] エストロゲン受容体欠損マウスを用いた骨芽細胞におけるエストロゲン応答遺伝子の検討2010
- Author(s)
  東浩太郎、池田和博、浦野友彦、大内尉義、井上聡
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] エストロゲンのgenomicおよびnongenomic作用(Genomic and nongenomic actions of estrogen)2010
- Author(s)
  東浩太郎、池田和博、大内尉義、井上聡
- Organizer
  The 6^<th> Young Endocrinologist conference
- Place of Presentation
  長崎
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] エストロゲン受容体欠損マウスを用いた骨芽細胞におけるエストロゲン応答遺伝子の検討2010
- Author(s)
  東浩太郎、池田和博、浦野友彦、大内尉義、井上聡
- Organizer
  第10回日本抗加齢医学会総会
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone absorption.2010
- Author(s)
  Azuma K, Casey S, Kirchner S, Ito M, Urano T, Horie K, Ouchi Y, Blumberg B, Inoue S
- Organizer
  IOF World Congress on Osteoporosis & 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] 核内受容体PXRノックアウトマウスは加齢に伴い変形性膝関節症様の変化を呈する2010
- Author(s)
  東浩太郎、Stephanie Casey、浦野友彦、大内尉義、Bruce Blumberg、井上聡
- Organizer
  第52回日本老年医学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] エストロゲンのgenomicおよびnongenomic作用2010
- Author(s)
  東浩太郎、池田和博、大内尉義、井上聡
- Organizer
  The 6^<th> Young Endocrinologist Conference
- Place of Presentation
  ハウステンボス(長崎)
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] [シンポジウム]性ホルモンと骨代謝-骨軟骨におけるエストロゲン作用2010
- Author(s)
  東浩太郎、大内尉義、井上聡
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] Pregnane X receptor knockout mice display osteopenia with reduced bone formation and enhanced bone absorption2010
- Author(s)
  AzumaK, Casey S, Kirchner S, Ito M, UranoT, Horie K, Ouchi Y, Blumberg B, Inoue S
- Organizer
  IOF World Congress on Osteoporosis & 10th European Congress on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis
- Place of Presentation
  Florence, Italy
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] [シンポジウム]性ホルモンと骨代謝-骨軟骨におけるエストロゲン作用2010
- Author(s)
  東浩太郎、大内尉義、井上聡
- Organizer
  第28回日本骨代謝学会学術集会
- Place of Presentation
  京王プラザホテル(東京)
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] 核内受容体PXRノックアウトマウスは加齢に伴い変形性膝関節症様の変化を呈する2010
- Author(s)
  東浩太郎、Stephanie Casey、浦野友彦、大内尉義、Bruce Blumberg、井上聡
- Organizer
  第52回日本老年医学会学術集会
- Place of Presentation
  神戸国際会議場(兵庫)
- Data Source
  KAKENHI-PROJECT-22790882
[Presentation] ER alpha-HDAC6 complex at plasma membrane mediates rapid tubulin deacetylation as a novel nongenomic estrogen action.2007
- Author(s)
  Azuma T, Sakai R, Inoue S, et. al.
- Organizer
  The Endocrine Society's 97th annual meeting
- Place of Presentation
  Toronto, Canada
- Data Source
  KAKENHI-PROJECT-18659083

1. 井上聡 (40251251)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
2. 浦野友彦 (20334386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. 塩之入温 (00401109)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大崎昭彦 (90291484)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKAYAMA Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. FUJIMURA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 井上聰

# of Collaborated Projects: 0 results

# of Collaborated Products: 30 results
8. 池田和博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 柴祥子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 鈴木貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Azuma Koutaro 東 浩太郎

Azuma Kotaro 東 浩太郎

AZUMA Kotaro 東 浩太郎

東 浩太郎 アズマ コウタロウ

Research Projects

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Co-Researchers

高齢者の認知機能・フレイルと関連するビタミンKによる新規蛋白質修飾の解明Principal Investigator

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TRIM47関連蛋白質を標的としポストゲノム診療を見据えた乳癌個別化医療の探索Principal Investigator

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Development of treatment strategy targeting mechanisms mediated by TRIM family proteinsPrincipal Investigator

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Investigation on the breast cancer-promoting effects of TRIM family proteins and its clinical applicationPrincipal Investigator

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Analysis of vitamin K functions on age-related diseases using organ-specific gene knockout mice.Principal Investigator

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ホルモン依存性の性差を生み出すエストロゲン受容体核内・核外作用機構の総合的解明Principal Investigator

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Analysis and treatment-application of novel nongenomic action of estrogen receptor mediated by protein deacetylationPrincipal Investigator

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エストロゲン受容体の核外作用を介したアセチル化の制御とシグナル伝達機構の解明Principal Investigator

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[Book] Vitamin K, SXR, and GGCX2017

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[Book] Nongenomic action of estrogen receptor in breast cancer. Estrogen Receptors: Mechanisms, Structure and Role in Disease2012

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[Journal Article] EBAG9-deficient mice display decreased bone mineral density with suppressed autophagy2024

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[Journal Article] Efp/TRIM25 and Its Related Protein, TRIM47, in Hormone-Dependent Cancers2022

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[Journal Article] TRIM47 activates NF-κB signaling via PKC-ε/PKD3 stabilization and contributes to endocrine therapy resistance in breast cancer2021

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Azuma Koutaro 東浩太郎

Azuma Kotaro 東浩太郎

AZUMA Kotaro 東浩太郎

東浩太郎アズマコウタロウ