Sutani Takashi 須谷尚史

… Alternative Names

SUTANI Takashi 須谷尚史

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Researcher Number	30401524
Other IDs	https://orcid.org/0000-0002-9959-9513
External Links
Affiliation (Current)	2024: 東京大学, 定量生命科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京大学, 定量生命科学研究所, 准教授 2018 – 2019: 東京大学, 定量生命科学研究所, 講師 2015 – 2017: 東京大学, 分子細胞生物学研究所, 講師 2010 – 2014: 東京大学, 分子細胞生物学研究所, 助教 2008 – 2009: 東京工業大学, 大学院・生命理工学研究科, 助教 … More 2007: Tokyo Institute of Technology, 大学院・生命理工学研究科, COE助教 2006: バイオ研究基盤支援総合センター, 産学官連携研究員 2006: 東京工業大学, バイオ研究基盤支援総合センター, 産学官連携研究員 Less
Review Section/Research Field	Principal Investigator Genetics/Genome dynamics / Molecular biology / Basic Section 43010:Molecular biology-related Except Principal Investigator Basic Section 56060:Ophthalmology-related / Broad Section G / Genome biology / Genome biology / 基礎ゲノム科学
Keywords	Principal Investigator 染色体 / 細胞周期 / ゲノム / 染色体高次構造 / 染色体凝縮 / 姉妹染色分体 / コヒーシン / 染色体分配 / Smc5/6複合体 / ゲノム不安定性 … More / 非B型DNA / DNA / バイオインフォマティクス / Hi-C / DNAトポロジー / DNA超らせん / Smc5/6 / コンデンシン / 単鎖DNA / ChIP-seq / ChIP-seq法 / 分裂酵母 / 転写 / 脱アセチル化 / アセチル化 / DNA複製 / ゲノム維持 / 維持 / 再編 / ゲノム構築 / マイクロアレイ / 出芽酵母 … More Except Principal Investigator コヒーシン / 常在細菌叢 / 加齢 / 性ホルモン / マイボーム腺 / 染色体高次構造 / 染色体動態 / 次世代シークエンサー / 染色体 / 染色体構造 / 転写制御 / ChIP-seq / 染色体構築 / 脂質生合成 / Sex steroid hormone / Lipidome / Microbiome / Dry Eye / MGD / Meibomian gland / prefab / コヒーシンローダー / 転写伸長反応 / ATPase / in vitro転写系 / ヒストン密度 / リモデリング複合体 / エンハンソソーム / 脂質 / 眼科学 / DNAシーケンス / Cutibacterium acnes / 脂質分析 / マイクロバイオーム / ドライアイ / マイボーム腺炎 / マイボーム腺機能不全 / ゲノム維持 / 染色体構築原理 / 機械学習 / コンデンシン / 細胞周期 / 染色体情報 / ChIP-seq解析 / 染色体可視化 / ゲノム / SMCタンパク / タンパクプロファイル解析 / 転写 / 染色体機能 / ゲノム構造 / 染色体複製 / 染色体凝縮 / 染色体分配 / DNAチップ / 脱アセチル化 / アセチル化修飾 / コヒーシン病 / 染色体モデル / ChIP-chip Less

Elucidation of regulatory mechanisms of lipid metabolism in meibomian glands by changes in aging and indigenous bacterial flora
- Principal Investigator
  
  鈴木智
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Generation and control of non-B form DNA in the nucleus: a genome-wide approachPrincipal Investigator
- Principal Investigator
  
  須谷尚史
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  The University of Tokyo
Regulation of Enhanceosome by Cohesin
- Principal Investigator
  
  白髭克彦
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  The University of Tokyo
Elucidation of the pathogenesis of the ocular surface diseases associated with meibomian gland lipids, commensal bacteria and sex steroid hormones
- Principal Investigator
  
  Suzuki Tomo
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of condensin-mediated control of DNA supercoiling and and its physiological rolesPrincipal Investigator
- Principal Investigator
  
  Sutani Takashi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  The University of Tokyo
Study of genome maintenance / inheritance mechanism based on chromosome 4D structure analysis
- Principal Investigator
  
  SHIRAHIGE KATSUHIKO
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Genome biology
- Research Institution
  The University of Tokyo
Understanding the molecular functions of the condensin complex in chromosome condensationPrincipal Investigator
- Principal Investigator
  
  SUTANI Takashi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  The University of Tokyo
A novel approach for the understanding of basic structure and behavior of human chromosomes
- Principal Investigator
  
  SHIRAHIGE Katsuhiko
- Project Period (FY)
  2010 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Genome biology
- Research Institution
  The University of Tokyo
Mechanism to establish cohesion specifically between sister chromatidsPrincipal Investigator
- Principal Investigator
  
  TAKASHI Sutani
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  The University of Tokyo
A Novel Genomic Approch for the Understanding of the Structure and Function of Chromosomes
- Principal Investigator
  
  SHIRAHIGE Katsuhiko
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  基礎ゲノム科学
- Research Institution
  Tokyo Institute of Technology
姉妹染色分体間の接着形成に必須なアドヘリン複合体の分子機能の探求Principal Investigator
- Principal Investigator
  
  須谷尚史
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Institute of Technology

All 2020 2019 2018 2017 2014 2013 2012 2011 2010 2009 2008 2006 Other

All Journal Article Presentation

[Journal Article] The microbiome of the meibum and ocular surface in healthy subjects.2020
- Author(s)
  Suzuki T, Sutani T, Nakai H, Shirahige K, Kinoshita S.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 61 Issue: 2 Pages: 18-18
- DOI
  10.1167/iovs.61.2.18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09996
[Journal Article] Bioinformatical dissection of fission yeast DNA replication origins2020
- Author(s)
  Koji Masuda, Claire Renard-Guillet, Katsuhiko Shirahige, Takashi Sutani
- Journal Title
  
  Open Biol .
  
  Volume: Volume 10Issue 7 Issue: 7 Pages: 200052-200052
- DOI
  10.1098/rsob.200052
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-20H05940, KAKENHI-PROJECT-20H05686
[Journal Article] ChIP-seq Analysis of Condensin Complex in Cultured Mammalian Cells.2017
- Author(s)
  Sakata T, Shirahige K, Sutani T.
- Journal Title
  
  Methods Mol Biol.
  
  Volume: 1515 Pages: 257-271
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H02369
[Journal Article] ChIP-seq analysis of condensin complex in cultured mammalian cells2017
- Author(s)
  Sakata, T., Shirahige, K., Sutani, T.
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 1515 Pages: 257-271
- DOI
  10.1007/978-1-4939-6545-8_16
- ISBN
  9781493965434, 9781493965458
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15J10909, KAKENHI-PROJECT-17K07281
[Journal Article] Dissecting the first and the second meiotic divisions using a marker-less drug-hypersensitive fission yeast.2014
- Author(s)
  Yuki Aoi, Masamitsu Sato, Takashi Sutani, Katsuhiko Shirahige, Tarun M Kapoor, and Shigehiro A Kawashima.
- Journal Title
  
  Cell cycle
  
  Volume: 13 Issue: 8 Pages: 1327-1334
- DOI
  10.4161/cc.28294
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J10270, KAKENHI-PROJECT-24570006, KAKENHI-PROJECT-25291041
[Journal Article] An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion.2010
- Author(s)
  Beckouet F, Hu B, Roig MB, Sutani T, Komata M, Uluocak P, Katis VL, Shirahige K, Nasmyth K.
- Journal Title
  
  Mol Cell.
  
  Volume: 39 Pages: 689-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221009
[Journal Article] The RSC chromatin-remodeling complex influences mitotic exit and adaptation to the spindle assembly checkpoint by controlling the Cdc14 phosphatase2010
- Author(s)
  Rossio V, Galati E, Ferrari M, Pellicioli A, Sutani T, Shirahige K, Lucchini G, Piatti S
- Journal Title
  
  J. Cell. Biol
  
  Volume: vol.191 Pages: 981-997
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770005
[Journal Article] An Smc3 acetylation cycle is essential for establishment of sister chromatid cohesion2010
- Author(s)
  Beckouet F, Hu B, Roig MB, Sutani T, Komata M, Uluocak P, Katis VL, Shirahige K, Nasmyth K
- Journal Title
  
  Mol. Cell
  
  Volume: vol.39 Pages: 689-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770005
[Journal Article] Yeast Wpl1 (Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction.2009
- Author(s)
  T.Sutani, T.Kawaguchi, R.Kanno, T.Itoh, K.Shirahige
- Journal Title
  
  Curr.Biol. 19
  
  Pages: 492-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101007
[Journal Article] Budding Yeast Wpl1(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion- Establishing Reaction2009
- Author(s)
  T. Sutani, T. Kawaguchi, R. Kanno, T. Itoh, K. Shirahige
- Journal Title
  
  Curr. Biol 19
  
  Pages: 492-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101007
[Journal Article] Budding Yeast Wpll(Rad61)-Pds5 Complex Counteracts Sister Chromatid Cohesion-Establishing Reaction.2009
- Author(s)
  T. Sutani, T. Kawaguchi, R. Kanno, T. Itoh, K. Shirahige
- Journal Title
  
  Curr. Biol 19
  
  Pages: 492-497
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18101007
[Journal Article] 複製フォークによる複製と分配の連携2006
- Author(s)
  加藤由起, 須谷尚史, 白髭克彦
- Journal Title
  
  細胞工学 25・5
  
  Pages: 492-497
- Data Source
  KAKENHI-PROJECT-18770149
[Presentation] マイボーム腺のマイクロバイオームの加齢性変化についての考察．2020
- Author(s)
  鈴木　智、須谷尚史、中井浩子、白鬚克彦、木下　茂．
- Organizer
  角膜カンファランス2020
- Data Source
  KAKENHI-PROJECT-19K09996
[Presentation] 眼表面マイクロバイオームの加齢性変化についての検討.2020
- Author(s)
  鈴木　智、須谷尚史、白髭克彦、木下茂.
- Organizer
  第20回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-19K09996
[Presentation] マイボーム腺常在細菌叢とmeibumの脂質組成との関連についての一考察．2020
- Author(s)
  鈴木　智、須谷尚史、白髭克彦、中井浩子、木下茂、Igor Butovich．
- Organizer
  第124回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-19K09996
[Presentation] Behavior of cohesive cohesin complex on human chromosomes2019
- Author(s)
  Takashi Sutani, Mai Ishibashi, Masashige Bando, Atsunori Yoshimura, Katsuhiko Shirahige
- Organizer
  EMBO workshop “Organization of bacterial and eukaryotic genomes by SMC complexes”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07281
[Presentation] Human microbiome of eyelid skin, conjunctival sac, and meibum of the meibomian gland.2019
- Author(s)
  Suzuki T, Sutani T,　Nakai H, Shirahige K, Kinoshita S.
- Organizer
  ARVO Annual Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09996
[Presentation] Characteristics of Smc5/6 binding sites revealed by machine learning-based modeling2018
- Author(s)
  Takashi Sutani, Kristian Jeppsson, Katsuhiko Shirahige, Camilla Bjorkengren
- Organizer
  The 11th 3R & 3C symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07281
[Presentation] Physical association of S. cerevisiae polo-like kinase Cdc5 with chromosomal cohesin facilitates DNA damage response2017
- Author(s)
  Sujiraporn Pakchuen、Mai Ishibashi、Katsuhiko Shirahige、Takashi Sutani
- Organizer
  2nd meeting on SMC proteins
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K07281
[Presentation] Condensin complex negates an inhibitory effect of gene transcription on mitotic chromosome segregation.2013
- Author(s)
  Takashi Sutani, Katsuhiko Shirahige
- Organizer
  7th International Fission Yeast Meeting
- Place of Presentation
  University of London, London, UK
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] Cohesin resolves interference between mitotic gene transcription and chromosome segregation.2013
- Author(s)
  Takashi Sutani, Toyonori Sakata, Mai Ishibashi, Ryuichiro Nakato, Masashige Bando, Katsuhiko Shirahige
- Organizer
  18th ICBM Symposium; SMC proteins from molecule to disease
- Place of Presentation
  東京大学弥生講堂（東京都文京区）
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] Transcription Regulation by SMC proteins2013
- Author(s)
  Takashi Sutani, Katsuhiko Shirahige
- Organizer
  Message from yeast to epigenetics
- Place of Presentation
  グランディア芳泉（福井県あわら市）
- Invited
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] コンデンシン複合体はM期遺伝子転写のもつ染色体分配に対する障害作用を解消する2013
- Author(s)
  須谷尚史、坂田豊典、中戸隆一郎、白髭克彦
- Organizer
  国立遺伝学研究所研究会「染色体DNAの安定維持の分子メカニズム」
- Place of Presentation
  国立遺伝学研究所（静岡県、三島市）
- Invited
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] コンデンシンは遺伝子転写がもつM期染色体分配に対する阻害的効果を中和する2012
- Author(s)
  須谷尚史、石橋舞、中戸隆一郎、白髭克彦
- Organizer
  第30回染色体ワークショップ
- Place of Presentation
  淡路夢舞台国際会議場（兵庫）
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] コンデンシンは遺伝子転写がもつM期染色体分配に対する阻害的効果を中和する2012
- Author(s)
  須谷尚史、中戸隆一郎、鈴木穣、白髭克彦
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Invited
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] 姉妹染色分体間の接着確立に必須なSmc3アセチル化の細胞周期制御2011
- Author(s)
  須谷尚史、古俣麻希子、鶴田祥悠、九十九雅理、白髭克彦
- Organizer
  第28回染色体ワークショップ
- Place of Presentation
  石川県加賀市
- Year and Date
  2011-01-12
- Data Source
  KAKENHI-PROJECT-22770005
[Presentation] Cell cycle regulation of Smc3 acetylation required for sister chromatid cohesion establishment2010
- Author(s)
  須谷尚史
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22770005
[Presentation] Cell cycle regulation of Smc3 acetylation required for sister chromatid cohesion establishment2010
- Author(s)
  Sutani T, Komata M, Tsuruta T, Tsukumo M, Shirahige K
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  兵庫県神戸市
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-22770005
[Presentation] 姉妹染色分体間接着形成に必須な出芽酵母Eco1の欠失変異はRad61/Pds5複合体内の変異で相槌される2008
- Author(s)
  須谷尚史
- Organizer
  第19回DNA複製・分配ワークショップ
- Place of Presentation
  伊豆市・ラフォーレ修善寺
- Year and Date
  2008-03-06
- Data Source
  KAKENHI-PROJECT-18770149
[Presentation] Expulsion of ongoing RNA polymerase II from mitotic chromosomes by condensin
- Author(s)
  Takashi Sutani, Toyonori Sakata, Katsuhiko Shirahige
- Organizer
  高等研究所カンファレンス "Chromoatin decoding"
- Place of Presentation
  国際高等研究所（京都府木津川市）
- Year and Date
  2014-05-12 – 2014-05-15
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] Condensin precludes interference from transcription-driven DNA unwinding in mitotic chromosome condensation
- Author(s)
  Takashi Sutani
- Organizer
  The 9th 3R Symposium "3R and beyond"
- Place of Presentation
  御殿場高原ホテル（静岡県御殿場市）
- Year and Date
  2014-11-17 – 2014-11-21
- Data Source
  KAKENHI-PROJECT-24570006
[Presentation] 染色体凝縮因子による染色体リセット
- Author(s)
  須谷尚史
- Organizer
  国立遺伝学研究所研究会「表現型と遺伝子型のミッシングリンクをつなぐ」
- Place of Presentation
  遺伝学研究所（静岡県三島市）
- Year and Date
  2014-06-27 – 2014-06-28
- Invited
- Data Source
  KAKENHI-PROJECT-24570006

1. SHIRAHIGE Katsuhiko (90273854)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. HIROTA Toru (50421368)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. ITOH Takehiko (90501106)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. Suzuki Tomo (30613236)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. 出来尾格 (80338128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 木下茂 (30116024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. 中戸隆一郎 (60583044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 土居雅夫 (20432578)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. SAKATA Toyonori

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Sutani Takashi 須谷 尚史

SUTANI Takashi 須谷 尚史

Research Projects

Research Products

Co-Researchers

Elucidation of regulatory mechanisms of lipid metabolism in meibomian glands by changes in aging and indigenous bacterial flora

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Generation and control of non-B form DNA in the nucleus: a genome-wide approachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of Enhanceosome by Cohesin

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the pathogenesis of the ocular surface diseases associated with meibomian gland lipids, commensal bacteria and sex steroid hormones

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of condensin-mediated control of DNA supercoiling and and its physiological rolesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study of genome maintenance / inheritance mechanism based on chromosome 4D structure analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Understanding the molecular functions of the condensin complex in chromosome condensationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A novel approach for the understanding of basic structure and behavior of human chromosomes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism to establish cohesion specifically between sister chromatidsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A Novel Genomic Approch for the Understanding of the Structure and Function of Chromosomes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

姉妹染色分体間の接着形成に必須なアドヘリン複合体の分子機能の探求Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The microbiome of the meibum and ocular surface in healthy subjects.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bioinformatical dissection of fission yeast DNA replication origins2020

Author(s)

Journal Title

DOI

Sutani Takashi 須谷尚史

SUTANI Takashi 須谷尚史