Tomochika Shinobu 友近忍

Researcher Number	30403679
Other IDs
Affiliation (Current)	2025: 山口大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2023: 山口大学, 大学院医学系研究科, 助教 2018 – 2023: 山口大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 55020:Digestive surgery-related Except Principal Investigator Basic Section 55020:Digestive surgery-related
Keywords	Principal Investigator TCRレパト / 大腸癌肝転移 / TCRレパトア / 癌 Except Principal Investigator 大腸癌 / 遺伝子多型 / 個別化医療 / 副作用診断チップ / ゲノム網羅的解析 / 進行大腸癌 … More / FOLFOXIRI療法 / 癌 / CyTOF / マスサイトメトリー / 腫瘍浸潤リンパ球 / 固形がん / がんペプチド療法 / 癌局所微小環境 / 負の免疫応答 / 免疫チェックポイント / ペプチドワクチン / バイオマーカー / 免疫チェックポイント阻害剤 / ペプチドワクチン療法 Less

Can Anti-EGFR Antibodies Turn Colorectal Cancer into Hot Tumors?Principal Investigator
- Principal Investigator
  
  Tomochika Shinobu
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Development of an in vitro diagnosis of adverse effects of FOLFOXIRI therapy for colorectal cancer
- Principal Investigator
  
  Suzuki Nobuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Analysis of CD4+FOXP3+ cells infiltrating colorectal tumors using CyTOF and their relationship to prognosis
- Principal Investigator
  
  YOSHIDA Shin
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University
Identification for biomarkers in cancer peptide vaccine therapy with immune checkpoint inhibitors
- Principal Investigator
  
  Suzuki Nobuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55020:Digestive surgery-related
- Research Institution
  Yamaguchi University

All 2024 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Effect of Paxillin Expression and Phosphorylation on Colorectal Cancer Prognosis and Metastasis2024
- Author(s)
  ZHENG HUANYU、TSUNEDOMI RYOUICHI、XU MING、ZHANG YING、KISHI HIROKO、KOBAYASHI SEI、TOMOCHIKA SHINOBU、NAKAJIMA MASAO、MATSUI HIROTO、TOKUMITSU YUKIO、SHINDO YOSHITARO、IIDA MICHIHISA、IOKA TATSUYA、NAGANO HIROAKI
- Journal Title
  
  Anticancer Research
  
  Volume: 44 Issue: 2 Pages: 511-520
- DOI
  10.21873/anticanres.16839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08850, KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756
[Journal Article] High serum proteinase-3 levels predict poor progression-free survival and lower efficacy of bevacizumab in metastatic colorectal cancer2024
- Author(s)
  Furuya Kei、Nakajima Masao、Tsunedomi Ryouichi、Nakagami Yuki、Xu Ming、Matsui Hiroto、Tokumitsu Yukio、Shindo Yoshitaro、Watanabe Yusaku、Tomochika Shinobu、Maeda Noriko、Iida Michihisa、Suzuki Nobuaki、Takeda Shigeru、Hazama Shoichi、Ioka Tatsuya、Hoshii Yoshinobu、Ueno Tomio、Nagano Hiroaki
- Journal Title
  
  BMC Cancer
  
  Volume: 24 Issue: 1 Pages: 165-165
- DOI
  10.1186/s12885-024-11924-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08874, KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-21K16448
[Journal Article] IL-6 Levels Correlate with Prognosis and Immunosuppressive Stromal Cells in Patients with Colorectal Cancer2023
- Author(s)
  Yamamoto Tsunenori、Tsunedomi Ryouichi、Nakajima Masao、Suzuki Nobuaki、Yoshida Shin、Tomochika Shinobu、Xu Ming、Nakagami Yuki、Matsui Hiroto、Tokumitsu Yukio、Shindo Yoshitaro、Watanabe Yusaku、Iida Michihisa、Takeda Shigeru、Hazama Shoichi、Tanabe Tsuyoshi、Ioka Tatsuya、Hoshii Yoshinobu、Kiyota Akifumi、et al.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: 30 Issue: 8 Pages: 5267-5277
- DOI
  10.1245/s10434-023-13527-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08850, KAKENHI-PROJECT-22K08874, KAKENHI-PROJECT-21K08711, KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-21K16448
[Journal Article] Anti-VEGF and Anti-EGFR Antibody Therapy on T-Cell Infiltration and TCR Variation in Metastatic Colorectal Cancer2023
- Author(s)
  XU MING、TSUNEDOMI RYOUICHI、KIYOTANI KAZUMA、TOMOCHIKA SHINOBU、FURUYA KEI、NAKAJIMA MASAO、MATSUI HIROTO、TOKUMITSU YUKIO、SHINDO YOSHITARO、YOSHIDA SHIN、IIDA MICHIHISA、SUZUKI NOBUAKI、TAKEDA SHIGERU、IOKA TATSUYA、HAZAMA SHOICHI、NAGANO HIROAKI
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 2 Pages: 613-620
- DOI
  10.21873/anticanres.16197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756
[Journal Article] IL-6 levels correlate with prognosis and immunosuppressive stromal cells in patients with colorectal cancer2023
- Author(s)
  Yamamoto Tsunenori, Tunedomi Ryouichi, Nakajima Masao, Suzuki Nobuaki, Yoshida Shin, Tomochika Shinobu, Nakagami Yuki, Xu Ming, Hazama Shoichi, Tanabe Tsuyoshi, Ioka Tatsuya, Hoshii Yoshinobu, Kiyota Akifumi, Takizawa Hitoshi, Kawakami Yutaka, Ueno Tomio, Nagano Hiroaki, et. al.
- Journal Title
  
  Annals of Surgical Oncology
  
  Volume: -
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09079
[Journal Article] Serum CCL7 Is a Novel Prognostic Biomarker of Metastatic Colorectal Cancer2022
- Author(s)
  CHIDIMATSU HIKARI、TSUNEDOMI RYOUICHI、NAKAGAMI YUKI、XU MING、NAKAJIMA MASAO、NAKASHIMA-NAKASUGA CHIYO、TOMOCHIKA SHINOBU、et al
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 1 Pages: 105-114
- DOI
  10.21873/anticanres.16139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-22K08874
[Journal Article] CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule2022
- Author(s)
  Nakagami Yuki、Hazama Shoichi、Suzuki Nobuaki、Yoshida Shin、Tomochika Shinobu、et al
- Journal Title
  
  BMC Cancer
  
  Volume: 22 Issue: 1 Pages: 1071-1071
- DOI
  10.1186/s12885-022-10181-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08755, KAKENHI-PROJECT-22K08874, KAKENHI-PROJECT-20H03534
[Journal Article] Identification of a Promiscuous Epitope Peptide Derived From HSP70.2019
- Author(s)
  Matsui H, Hazama S, Tamada K, Udaka K, Irie A, Nishimura Y, Miyakawa T, Doi S, Nakajima M, Kanekiyo S, Tokumitsu Y, Shindo Y, Tomochika S, Yoshida S, Iida M, Suzuki N, Takeda S, Yamamoto S, Yoshino S, Ueno T, Nagano H
- Journal Title
  
  J Immunother
  
  Volume: 42 Issue: 7 Pages: 244-250
- DOI
  10.1097/cji.0000000000000274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08008, KAKENHI-PROJECT-18K08646, KAKENHI-PROJECT-18K08681, KAKENHI-PROJECT-15H05791, KAKENHI-PROJECT-16H02474, KAKENHI-PROJECT-19K07775
[Presentation] ASSOCIATION BETWEEN SINGLE NUCLEOTIDE POLYMORPHISMS AND NEUTROPENIA CAUSED BY TRIPLET CHEMOTHERAPY IN PATIENTS WITH PANCREATIC CANCER2023
- Author(s)
  Tsunedomi Ryouichi, Kanesada Gen, Yamamoto Tsunenori, Kimura Yuta, Nakajima Masao, Shindo Yoshitaro, Matsui Hiroto, Tokumitsu Yukio, Watanabe Yusaku, Tomochika Sinobu, Iida Michihisa, Suzuki Nobuaki, Takeda Sigeru, Ioka Tatsuya, Nagano Hiroaki
- Organizer
  UEG Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08799
[Presentation] 大腸癌切除例における IL-6 と予後および腫瘍浸潤免疫細胞の関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第35回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 大腸癌患者における血中 IL-6 濃度と腫瘍微小環境における免疫抑制状態、予後との関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 大腸癌患者における腫瘍内サイトカイン発現と血中サイトカイン濃度の関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第43回癌免疫外科研究会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 転移性大腸癌における T 細胞浸潤および TCR 変動に対する抗 VEGF2022
- Author(s)
  徐明、恒富亮一、清谷一馬、友近忍、中島正夫、松井洋人、徳光幸生、新藤芳太郎、吉田晋、飯田通久、鈴木伸明、武田茂、井岡達也、硲彰一、永野浩昭
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21K08755
[Presentation] 大腸癌術前血中サイトカイン濃度と腫瘍内サイトカイン発現の関係2022
- Author(s)
  山本常則、吉田晋、徐明、友近忍、中上裕有樹、鈴木伸明、硲彰一、永野浩昭
- Organizer
  第31回日本癌病態治療研究会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 進行・再発大腸癌の予後バイオマーカーとしての血清 Proteinase-3 の検討2021
- Author(s)
  古谷圭、硲彰一、鈴木伸明、吉田晋、友近忍、松隈聰、松井洋人、徳光幸生、新藤芳太郎、渡邊裕策、飯田通久、武田茂、井岡達也、永野浩昭
- Organizer
  第34回日本バイオセラピィ学会学術集会総会
- Data Source
  KAKENHI-PROJECT-20K09079
[Presentation] 大腸癌切除例における腫瘍浸潤リンパ球と血中炎症関連マーカーの関係の検討2020
- Author(s)
  山本常則、硲彰一、新藤芳太郎、徳光幸生、友近忍、吉田晋、飯田通久、鈴木伸明、武田茂、永野浩昭
- Organizer
  日本消化器外科学会
- Data Source
  KAKENHI-PROJECT-20K09079

1. Suzuki Nobuaki (50526910)

# of Collaborated Projects: 4 results

# of Collaborated Products: 11 results
2. 硲彰一 (50253159)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
3. 恒富亮一 (10420514)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
4. YOSHIDA Shin (60554805)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. 徐明 (40645503)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
6. 中上裕有樹 (30843304)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 渡邊裕策 (80799437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. TANABE Tuyoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 新藤芳太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
10. 永野浩昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 入江厚

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tomochika Shinobu 友近 忍

Research Projects

Research Products

Co-Researchers

Can Anti-EGFR Antibodies Turn Colorectal Cancer into Hot Tumors?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of an in vitro diagnosis of adverse effects of FOLFOXIRI therapy for colorectal cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of CD4+FOXP3+ cells infiltrating colorectal tumors using CyTOF and their relationship to prognosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification for biomarkers in cancer peptide vaccine therapy with immune checkpoint inhibitors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Effect of Paxillin Expression and Phosphorylation on Colorectal Cancer Prognosis and Metastasis2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High serum proteinase-3 levels predict poor progression-free survival and lower efficacy of bevacizumab in metastatic colorectal cancer2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-6 Levels Correlate with Prognosis and Immunosuppressive Stromal Cells in Patients with Colorectal Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-VEGF and Anti-EGFR Antibody Therapy on T-Cell Infiltration and TCR Variation in Metastatic Colorectal Cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] IL-6 levels correlate with prognosis and immunosuppressive stromal cells in patients with colorectal cancer2023

Author(s)

Journal Title

Data Source

[Journal Article] Serum CCL7 Is a Novel Prognostic Biomarker of Metastatic Colorectal Cancer2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of a Promiscuous Epitope Peptide Derived From HSP70.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] ASSOCIATION BETWEEN SINGLE NUCLEOTIDE POLYMORPHISMS AND NEUTROPENIA CAUSED BY TRIPLET CHEMOTHERAPY IN PATIENTS WITH PANCREATIC CANCER2023

Author(s)

Organizer

Data Source

[Presentation] 大腸癌切除例における IL-6 と予後および腫瘍浸潤免疫細胞の関係2022

Author(s)

Organizer

Data Source

[Presentation] 大腸癌患者における血中 IL-6 濃度と腫瘍微小環境における免疫抑制状態、予後との関係2022

Author(s)

Organizer

Data Source

[Presentation] 大腸癌患者における腫瘍内サイトカイン発現と血中サイトカイン濃度の関係2022

Tomochika Shinobu 友近忍

[Presentation] 大腸癌切除例における腫瘍浸潤リンパ球と血中炎症関連マーカーの関係の検討2020