KANO Arihiro 狩野有宏

… Alternative Names

Researcher Number	30403950
Affiliation (Current)	2020: 九州大学, 先導物質化学研究所, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2018: 九州大学, 先導物質化学研究所, 准教授 2010 – 2014: Kyushu University, 先導物質化学研究所, 准教授 2007 – 2009: 九州大学, 先導物質化学研究所, 助教 2006: 九州大学, 先導物質化学研究所, 助手
Review Section/Research Field	Principal Investigator Biomedical engineering/Biological material science / Living organism molecular science / Tumor therapeutics Except Principal Investigator Biomedical engineering/Biological material science / Science and Engineering
Keywords	Principal Investigator がん / 腫瘍 / 免疫抑制 / IFN-γ / 薬物伝達システム / 核酸医薬 / カチオン性高分子 / 腫瘍集積性 / 高分子構造・物性 / 生体材料 … More Except Principal Investigator 免疫寛容 / 肝類洞内皮細胞 / ヒアルロン酸 / バイオコンジュゲート / 抗原提示 / カチオン性高分子 / ＤＮＡ / 核酸酵素 / ペプチド / 脂質膜 / グラフト共重合体 / 高分子電解質複合体 / 核酸検出 / グラフト共重合体」 / DNA / 酵素 / ターンオーバー / カチオン性共重合体 / リポソーム / 生体膜 / ベシクル-シート転移 / 薬物送達 / デオキシリボザイム / 遺伝子解析 / カチオン性くし型共重合体 / ハイブリダイゼーション / 核酸シャペロン / 細胞内デリバリー / DDS / DNA鎖交換 / くし型共重合体 / 両親媒性ペプチド Less

がん細胞分泌性免疫抑制因子の同定による腫瘍悪性化機構の解明Principal InvestigatorOngoing
- Principal Investigator
  
  狩野有宏
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyushu University
Search for immunoregulatory factors derived from LSECs and Cancer cellsPrincipal Investigator
- Principal Investigator
  
  KANO Arihiro
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Living organism molecular science
- Research Institution
  Kyushu University
Evaluation of cellular functions by imaging cellular nucleic acids
- Principal Investigator
  
  Maruyama Atsushi
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Tokyo Institute of Technology
  Kyushu University
PEG-grafted linear cationic polymer for tumor accumulation and cell penetrationPrincipal Investigator
- Principal Investigator
  
  KANO Arihiro
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kyushu University
免疫疾患治療を目指した効率的寛容誘導法としてのネオグリコ抗原開発
- Principal Investigator
  
  MARUYAMA Atsushi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kyushu University

All 2019 2018 2017 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] がん細胞分泌性免疫抑制因子の同定による腫瘍悪性化機構の解明2019
- Author(s)
  狩野有宏
- Journal Title
  
  メディカル・サイエンス・ダイジェスト
  
  Volume: 45 Pages: 16-19
- Data Source
  KAKENHI-PROJECT-17K07219
[Journal Article] Macrophage Colony-Stimulating Factor mediates its Immunosuppressive Activity through the Emerging Myeloid Cells during Tumor Progression2017
- Author(s)
  Moses Kamita, Mitsuru Shindo, Arihiro Kano
- Journal Title
  
  EVERGREEN
  
  Volume: 4 Pages: 18-22
- NAID
  120006466408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K07219
[Journal Article] Tumor cell secretion of soluble factor(s) for specific immunosuppression2015
- Author(s)
  Arihiro Kano
- Journal Title
  
  Scientific Reports
  
  Volume: 5
- DOI
  10.1038/srep08913
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24510300
[Journal Article] Drastic stabilization of parallel DNA hybridizations by a polylysine comb-type copolymer with hydrophilic graft chain2014
- Author(s)
  D. Miyoshi, Y. M. Ueda, N. Shimada, S. I. Nakano, N. Sugimoto, A. Maruyama
- Journal Title
  
  ChemMedChem
  
  Volume: 9 Pages: 2156-2163
- DOI
  10.1002/cmdc.201402157
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23107007, KAKENHI-PROJECT-24245033, KAKENHI-PROJECT-24350089, KAKENHI-PUBLICLY-26107720
[Journal Article] Reversibly Cross-linked Polymeric Micelles Formed by Autonomously Exchangeable Dynamic Covalent Bonds2013
- Author(s)
  M. Nishihara, K. Imato, A. Irie, T. Kanehara, A. Kano, A. Maruyama, A. Takahara, H. Otsuka
- Journal Title
  
  Chem. Lett.
  
  Volume: 42 Pages: 377-379
- NAID
  10031162179
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23107007
[Journal Article] Polyelectrolyte-Assisted Transconformation of Stem-loop DNA2013
- Author(s)
  J. Du, L. Wu, N. Shimada, A. Kano, A. Maruyama
- Journal Title
  
  Chem. Commun.
  
  Volume: 49 Pages: 475-477
- DOI
  10.1039/c2cc37139a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23240074, KAKENHI-PLANNED-23107007
[Journal Article] Dual crosslinked hydrogel nanoparticles by nanogel bottom-up method for sustained-recles delivery.2012
- Author(s)
  Asako Shimoda, et al
- Journal Title
  
  Col. Surf., B: Biointerfaces,
  
  Volume: (in press) Pages: 38-44
- DOI
  10.1016/j.colsurfb.2011.09.025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-10J03768, KAKENHI-PROJECT-20240047, KAKENHI-PLANNED-22114009, KAKENHI-PLANNED-23107007
[Journal Article] Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA2011
- Author(s)
  Kano, A., Moriyama, K., Yamano, T., Nakamura, I., Shimada, N., Maruyama, A.
- Journal Title
  
  Journal of Control Release
  
  Volume: 149 Pages: 2-7
- NAID
  120004951559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500410
[Journal Article] Grafting of poly (ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA.2011
- Author(s)
  Kano, A., Moriyama, K., Yamano, T., Nakamura, I., Shimada, N., Maruyama, A.
- Journal Title
  
  J Control Release 149(1)
  
  Pages: 2-7
- NAID
  120004951559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500410
[Journal Article] Grafting of poly(ethylene glycol)to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA2010
- Author(s)
  Kano, A., Moriyama, K., Yamano, T., Nakamura, I., Shimada, N., Maruyama, A.
- Journal Title
  
  J Control Release (in press)
- NAID
  120004951559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500410
[Journal Article] Polymer brush-Stabilized polyplex for a siRNA carrier with long blood circulatory half-life. Adv. Mater. Res.2008
- Author(s)
  Kano, A., Yamano, T., Choi, S.W., Maruyama, A.
- Journal Title
  
  Adv. Mater. Res. (Zuerich, Switz.) FIELD Full Journal Title : Advanced Materials Research (Zuerich, Switzerland)(Pt.1, Multi-Functional Materials and Structures)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] 4T1移植担がんマウスの免疫抑制2018
- Author(s)
  狩野有宏、山下聖人、公せい、Moses K Kamita、新藤充
- Organizer
  日本分子生物学会第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17K07219
[Presentation] Role of M-CSF expressed from 4T1 tumor cells in immune activation2018
- Author(s)
  Jing Gong, Moses Kamita, Mitsuru Shindo, Arihiro Kano
- Organizer
  2018 IMCE International Symposium
- Data Source
  KAKENHI-PROJECT-17K07219
[Presentation] M-CSF suppresses IFN-γ secretion in splenocytes of tumor-bearing mice2017
- Author(s)
  公せい, Kamita Moses, 新藤充, 狩野有宏
- Organizer
  2017年生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-17K07219
[Presentation] ポリ(L-リシン)-グラフト-ポリエチレングリコール共重合体(PLL-g-PEG)の光線力学療法剤ポルフィマーナトリウムとの相互作用と腫瘍デリバリー2010
- Author(s)
  狩野有宏、中村いずみ、森山健司、嶋田直彦、丸山厚
- Organizer
  第59回高分子討論会
- Place of Presentation
  札幌
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] PLL-g-PEG共重合体と光線力学療法剤の複合化と腫瘍集積性2010
- Author(s)
  谷脇勇輝、森山健司、中村いずみ、嶋田直彦、狩野有宏、丸山厚
- Organizer
  第32回日本バイオマテリアル学会大会
- Place of Presentation
  広島
- Year and Date
  2010-11-30
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] 水溶性グラフト高分子の腫瘍集積性とドラッグデリバリー2010
- Author(s)
  狩野有宏
- Organizer
  九州地区高分子若手研究会・夏の講演会
- Place of Presentation
  北九州
- Year and Date
  2010-07-09
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] Complex Formation and Tumor Accumulation of Porfimer Sodium with PLL-g-PEG Copolymer for Photodynamic Therapy2010
- Author(s)
  Arihiro Kano, Yuuki Taniwaki, Takeshi Yamano, Izumi Nakamura, Naohiko Shimada, Atsushi Maruyama
- Organizer
  2010 International Symposium of Materials on Regenerative Medicine
- Place of Presentation
  Zhunan, Taiwan
- Year and Date
  2010-11-05
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] siRNAとの相互作用に及ぼすポリリシン側鎖にグラフトしたPEG鎖の影響2009
- Author(s)
  狩野有宏, 中村いずみ, 山野剛, 嶋田直彦, 丸山厚
- Organizer
  遺伝子・デリバリー研究会第9回シンポジウム
- Place of Presentation
  大阪
- Year and Date
  2009-07-11
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] ドラッグデリバリー担体としてのポリエチレングリコールグラフト共重合体の評価2009
- Author(s)
  森山健司, 中村いずみ, 狩野有宏, 丸山厚
- Organizer
  第24回生体機能関連化学シンポジウム若手フォーラム
- Place of Presentation
  福岡
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] PLL-g-PEG共重合体の腫瘍集積性の解析とsiRNAデリバリーへの応用2008
- Author(s)
  狩野有宏、山野剛、丸山厚
- Organizer
  第24回日本DDS学会
- Place of Presentation
  東京
- Year and Date
  2008-06-29
- Data Source
  KAKENHI-PROJECT-20500410
[Presentation] Hyaluronan bioconjugates for targeted delivery to sinusoidal endothelial cells in liver2007
- Author(s)
  A. Kano, et. al.
- Organizer
  IMRAM-England-IMCE 1st Joint Workshop
- Place of Presentation
  Fukuoka
- Year and Date
  2007-10-30
- Data Source
  KAKENHI-PROJECT-18650131
[Presentation] マウス乳がん細胞4T1が分泌する免疫抑制因子の解析
- Author(s)
  狩野有宏
- Organizer
  日本生化学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-24510300
[Presentation] IFN-γ産生を指標にした乳がん細胞4T1担持マウスの免疫抑制性の解析
- Author(s)
  狩野有宏
- Organizer
  日本インターフェロン・サイトカイン学会
- Place of Presentation
  東京工業大学大岡山キャンパス蔵前会館
- Year and Date
  2015-07-17 – 2015-07-18
- Data Source
  KAKENHI-PROJECT-24510300

1. MARUYAMA Atsushi (40190566)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. SHIMADA NAOHIKO (10423972)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 山吉麻子 (70380532)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MIYOSHI Daisuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 杉本直己

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 澤田晋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 秋吉一成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KANO Arihiro 狩野 有宏

狩野 有宏 カノウ アリヒロ

Research Projects

Research Products

Co-Researchers

がん細胞分泌性免疫抑制因子の同定による腫瘍悪性化機構の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for immunoregulatory factors derived from LSECs and Cancer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of cellular functions by imaging cellular nucleic acids

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

PEG-grafted linear cationic polymer for tumor accumulation and cell penetrationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

免疫疾患治療を目指した効率的寛容誘導法としてのネオグリコ抗原開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] がん細胞分泌性免疫抑制因子の同定による腫瘍悪性化機構の解明2019

Author(s)

Journal Title

Data Source

[Journal Article] Macrophage Colony-Stimulating Factor mediates its Immunosuppressive Activity through the Emerging Myeloid Cells during Tumor Progression2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Tumor cell secretion of soluble factor(s) for specific immunosuppression2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Drastic stabilization of parallel DNA hybridizations by a polylysine comb-type copolymer with hydrophilic graft chain2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reversibly Cross-linked Polymeric Micelles Formed by Autonomously Exchangeable Dynamic Covalent Bonds2013

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Polyelectrolyte-Assisted Transconformation of Stem-loop DNA2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dual crosslinked hydrogel nanoparticles by nanogel bottom-up method for sustained-recles delivery.2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Grafting of poly (ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA.2011

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Grafting of poly(ethylene glycol)to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA2010

KANO Arihiro 狩野有宏

狩野有宏カノウアリヒロ