Sugimoto Koichi 杉本浩一

… Alternative Names

杉本浩一スギモトコウイチ

SUGIMOTO Koichi 杉本浩一

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Researcher Number	30404867
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2017 – 2023: 福島県立医科大学, 医学部, 准教授 2008 – 2011: Fukushima Medical University, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Circulatory organs internal medicine Except Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine
Keywords	Principal Investigator マトリックスメタロプロテアーゼ / 肺高血圧 / 動脈硬化 / シグナル伝達 / 血管内皮細胞 / TGF-β / 内皮間葉移行 / DNA損傷 / 脂質代謝異常症 / 血管リモデリング … More / 右室肥大 / Smad / 一酸化窒素 / matrix metalloprotease / matrix metalloproteinase / 脂質異常症 / 肺高血圧症 / マトリックスメタロブロテアーゼ / 血管炎症 / RAGE / HMGB-1 / 酸化LDL受容体 / 血管内皮機能不全 / 分子血管病態学 … More Except Principal Investigator 肺高血圧症 / 遺伝子 / 遺伝子変異 / 治療反応性 / 重症度 / 循環器 / 心臓超音波検査 / 右心機能評価 / 画像診断 / 臨床診断 / 生理検査 / バイオマーカー / 予後予測 / 治療効果判定 Less

肺動脈性肺高血圧症の内皮間葉分化転換におけるDNA損傷応答とTGF-βの役割Principal Investigator
- Principal Investigator
  
  杉本浩一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Fukushima Medical University
Study on the difference of severity and treatment response of pulmonary hypertension
- Principal Investigator
  
  Nakazato Kazuhiko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Fukushima Medical University
Effects of high-fat diet on pulmonary hypertension and role of MT1-MMP as a biomarkerPrincipal Investigator
- Principal Investigator
  
  Sugimoto Koichi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Fukushima Medical University
Study on diagnosis and treatment effect evaluation of pulmonary hypertension by biomarker and imaging modality
- Principal Investigator
  
  Nakazato Kazuhiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Fukushima Medical University
The novel molecular mechanism of membrane type1 matrix metallo proteinase(MT1-MMP) in vascular inflammationPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Koichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukushima Medical University
Role of LOX-1-MT1-MMP axis in oxidized LDL-triggered endothelial dysfunctionPrincipal Investigator
- Principal Investigator
  
  SUGIMOTO Koichi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Fukushima Medical University

All 2021 2020 2019 2018 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils2021
- Author(s)
  Kimishima Yusuke、Misaka Tomofumi、Yokokawa Tetsuro、Wada Kento、Ueda Koki、Sugimoto Koichi、Minakawa Keiji、Nakazato Kazuhiko、Ishida Takafumi、Oshima Motohiko、Koide Shuhei、Shide Kotaro、Shimoda Kazuya、Iwama Atsushi、Ikeda Kazuhiko、Takeishi Yasuchika
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 6177-6177
- DOI
  10.1038/s41467-021-26435-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08365, KAKENHI-PROJECT-19K08523, KAKENHI-PROJECT-19K08819, KAKENHI-PROJECT-19K17572, KAKENHI-PROJECT-20K17088, KAKENHI-PROJECT-20H03713, KAKENHI-PROJECT-20K08428, KAKENHI-PROJECT-20K08494, KAKENHI-PROJECT-21K08112, KAKENHI-PROJECT-21K08399
[Journal Article] Pulmonary Hypertension and Hereditary Hemorrhagic Telangiectasia Related to an <i>ACVRL1</i> Mutation2020
- Author(s)
  Yokokawa T, Sugimoto K, Kimishima Y, Misaka T, Yoshihisa A, Morisaki H, Yamada O, Nakazato K, Ishida T, Takeishi Y.
- Journal Title
  
  Intern. Med.
  
  Volume: 59 Issue: 2 Pages: 221-227
- DOI
  10.2169/internalmedicine.3625-19
- NAID
  130007785091
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2020-01-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17532, KAKENHI-PROJECT-20K08428
[Journal Article] Significance of Pulmonary Vascular Resistance and Diastolic Pressure Gradient on the New Definition of Combined Post-Capillary Pulmonary Hypertension2020
- Author(s)
  Sugimoto K, Yoshihisa A, Nakazato K, Yokokawa T, Misaka T, Oikawa M, Kobayashi A, Yamaki T, Kunii H, Ishida T, Takeishi Y.
- Journal Title
  
  Int. Heart J.
  
  Volume: 61 Issue: 2 Pages: 301-307
- DOI
  10.1536/ihj.19-476
- NAID
  130007821526
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2020-03-28
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17532, KAKENHI-PROJECT-20K08428
[Journal Article] Senescence Marker Protein 30 Deficiency Exacerbates Pulmonary Hypertension in Hypoxia-Exposed Mice2019
- Author(s)
  Sugimoto Koichi、Yokokawa Tetsuro、Misaka Tomofumi、Nakazato Kazuhiko、Ishida Takafumi、Takeishi Yasuchika
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 6 Pages: 1430-1434
- DOI
  10.1536/ihj.19-190
- NAID
  130007753858
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-11-30
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17572, KAKENHI-PROJECT-17K09516
[Journal Article] Soluble neprilysin does not correlate with prognosis in pulmonary hypertension2019
- Author(s)
  Yoshihisa Akiomi、Yokokawa Tetsuro、Misaka Tomofumi、Oikawa Masayoshi、Kobayashi Atsushi、Yamaki Takayoshi、Sugimoto Koichi、Kunii Hiroyuki、Nakazato Kazuhiko、Takeishi Yasuchika
- Journal Title
  
  ESC Heart Failure
  
  Volume: 6 Issue: 2 Pages: 291-296
- DOI
  10.1002/ehf2.12404
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09447, KAKENHI-PROJECT-17K16018, KAKENHI-PROJECT-19K17572, KAKENHI-PROJECT-17K09516
[Journal Article] Electrocardiographic Criteria of Right Ventricular Hypertrophy in Patients with Chronic Thromboembolic Pulmonary Hypertension after Balloon Pulmonary Angioplasty2019
- Author(s)
  Yokokawa Tetsuro、Sugimoto Koichi、Nakazato Kazuhiko、Misaka Tomofumi、Oikawa Masayoshi、Kobayashi Atsushi、Yoshihisa Akiomi、Yamaki Takayoshi、Kunii Hiroyuki、Ishida Takafumi、Takeishi Yasuchika
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 15 Pages: 2139-2144
- DOI
  10.2169/internalmedicine.2320-18
- NAID
  130007686856
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-08-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09447, KAKENHI-PROJECT-17K09516
[Journal Article] The Fibrosis-4 Index Is Useful for Predicting Mortality in Patients with Pulmonary Hypertension due to Left Heart Disease2019
- Author(s)
  Tetsuro Yokokawa, Koichi Sugimoto, Akiomi Yoshihisa, Takuya Goto, Tomofumi Misaka, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi
- Journal Title
  
  Int. Heart J.
  
  Volume: 60 Issue: 5 Pages: 1147-1153
- DOI
  10.1536/ihj.19-034
- NAID
  130007719002
- ISSN
  1349-2365, 1349-3299
- Year and Date
  2019-09-27
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09516
[Journal Article] Liver fibrosis marker, 7S domain of collagen type IV, in patients with pre-capillary pulmonary hypertension2018
- Author(s)
  8.Yoshihisa A, Kimishima Y, Kiko T, Sato Y, Watanabe S, Kanno Y, Abe S, Miyata-Tatsumi M, Sato T, Suzuki S, Oikawa M, Kobayashi A, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Ishida T, Takeishi Y
- Journal Title
  
  Int J Cardiol
  
  Volume: 258 Pages: 269-274
- DOI
  10.1016/j.ijcard.2018.01.138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09516, KAKENHI-PROJECT-17K10449, KAKENHI-PROJECT-16K09447
[Journal Article] Involvement of membrane type 1-matrix metalloproteinase(MT1-MMP) in RAGE activation signaling pathways2011
- Author(s)
  Kamioka M, Ishibashi T, Ohkawara H, Nagai R, Sugimoto K, Uekita H, Matsui T, Yamagishi S, Ando K, Sakamoto T, Takuwa Y, Wada I, Shiomi M, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Cell Physiol
  
  Volume: 226 Pages: 1554-1563
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Adaptive servo ventilation improves cardiac dysfunction and prognosis in chronic heart failure patients with Cheyne-Stokes respiration2011
- Author(s)
  Yoshihisa A, Shimizu T, Owada T, Nakamura Y, Iwaya S, Yamauchi H, Miyata M, Hoshino Y, Sato T, Suzuki S, Sugimoto K, Yamaki T, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y.
- Journal Title
  
  Int Heart J
  
  Volume: 52 Pages: 218-223
- NAID
  130000971165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Crucial role of membrane type 1 matrix metalloproteinase(MT1-MMP) in RhoA/Rac1-dependent signaling pathways in thrombin-stimulated endothelial cells2011
- Author(s)
  Ando K, Ishibashi T, Ohkawara H, Inoue N, Sugimoto K, Uekita H, Hu C, Okamoto Y, Takuwa Y, Takeishi Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 18 Pages: 762-773
- NAID
  130004845389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Flow-mediated dilatation identifies impaired endothelial function in patients with sleep apnea syndrome2010
- Author(s)
  Yoshihisa A, Owada T, Hoshino Y, Miyata M, Misaka T, Sato T, Suzuki S, Sakamoto N, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Ishibashi T, Takeishi Y.
- Journal Title
  
  Fukushima J Med Sci
  
  Volume: 56 Pages: 115-120
- NAID
  130000419018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Advanced glycation end product-mediated matrix metallo-proteinase-9 and apoptosis via renin-angiotensin system in type 2 diabetes2010
- Author(s)
  Ishibashi T, Sugimoto K, et al
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 17 Pages: 578-589
- NAID
  130004845318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Preventive effects of pravastatin on thrombin-triggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo2010
- Author(s)
  Ohkawara H, Ishibashi T, Saitoh S, Inoue N, Sugimoto K, Kamioka M, Uekita H, Kaneshiro T, Ando K, Takuwa Y, Maruyama Y, Takeishi Y.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 88 Pages: 492-501
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Flow-mediated dilatation identifies impaired endothelial function in patients with sleep apnea syndrome2010
- Author(s)
  Yoshihisa A, Sugimoto K, et al
- Journal Title
  
  Fukushima Journal of Medical Science
  
  Volume: 56 Pages: 115-120
- NAID
  130000419018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Blockade of renin-angiotensin system attenuates advanced glycation end products-mediated signaling pathways2010
- Author(s)
  Kamioka M, Sugimoto K, et al
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 17 Pages: 590-600
- NAID
  130004845319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Preventive effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by repeated epicardial coronary artery endothelial denudation in pigs2010
- Author(s)
  Osugi T, Saitoh S, Matsumoto K, Muto M, Aikawa K, Ohkawara H, Sugimoto K, Kamioka M, Ishibashi T, Maruyama Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 17 Pages: 54-63
- NAID
  130004444372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Blockade of renin-angiotensin system attenuates advanced glycation end products-mediated signaling pathways2010
- Author(s)
  Kamioka M, Ishibashi T, Sugimoto K, Uekita H, Nagai R, Sakamoto N, Ando K, Ohkawara H, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 17 Pages: 590-600
- NAID
  130004845319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Advanced glycation end product-mediated matrix metallo-proteinase-9 and apoptosis via renin-angiotensin system in type 2 diabetes2010
- Author(s)
  Ishibashi T, Kawaguchi M, Sugimoto K, Uekita H, Sakamoto N, Yokoyama K, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 17 Pages: 578-589
- NAID
  130004845318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca^<2+> signaling pathways in endothelial cells2009
- Author(s)
  Sakamoto N, Ishibashi T, Sugimoto K, Sawamura T, Sakamoto T, Inoue N, Saitoh S, Kamioka M, Uekita H, Ohkawara H, Suzuki K, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Cell Physiol
  
  Volume: 220 Pages: 706-715
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Inoue N, Kamioka M, Uekita H, Ohkawara H, Sakamoto T, Sakamoto N, Okamoto Y, Takuwa Y, Kakino A, Fujita Y, Tanaka T, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  Cardiovasc Res
  
  Volume: 84 Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] RhoA and Rac1 changes in the atherosclerotic lesions of WHHLMI rabbits2009
- Author(s)
  Ohkawara H, Ishibashi T, Shiomi M, Sugimoto K, Uekita H, Kamioka M, Takuwa Y, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  J Atheroscler Thromb
  
  Volume: 16 Pages: 846-856
- NAID
  10026144512
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790718
[Journal Article] LOX-1-MT1-MMP Axis is Crucial for RhoA and Rac1 Activation Induced by Oxidized Low-Density Lipoprotein in Endothelial Cells.2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Inoue N, Kamioka M, Uekita H, Ohkawara H, Sakamoto T, Sakamoto N, Okamoto Y, Takuwa Y, Kakino A, Fujita Y, Tanaka T, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  Cardiovascular Research 84
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790538
[Journal Article] LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells.2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Inoue N, Kamioka M, Uekita H, Ohkawara H, Sakamoto T, Sakamoto N, Okamoto Y, Takuwa Y, Kakino A, Fujita Y, Tanaka T, Teramoto T, Maruyama Y, Takeishi Y.
- Journal Title
  
  Cardiovasc Res. 84(1)
  
  Pages: 127-136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Serum level of membrane type 1-matrix metalloproteinase inversely co-relates with right ventricular systolic pressure and mean pulmonary artery pressure in pulmonary hypertension2021
- Author(s)
  Sugimoto Koichi
- Organizer
  American Heart Association Scientific Sessions 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08428
[Presentation] High-fat diet delays pulmonary artery reverse remodeling in mice with hypoxia-induced pulmonary hypertension.2020
- Author(s)
  杉本　浩一
- Organizer
  第84回　日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08080
[Presentation] Relationship between treatment effect of riociguat and methemoglobin in patients with pulmonary hypertension2019
- Author(s)
  Koichi Sugimoto, Akiomi Yoshihisa, Kazuhiko Nakazato, Masayoshi Oikawa, Atsushi Kobayashi, Takayoshi Yamaki, Hiroyuki Kunii, Takafumi Ishida, Yasuchika Takeishi
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] Endothelin-1 upregulates activin receptor-like kinase-1 (ALK-1) expression through Gi-RhoA dependent pathway in human pulmonary arterial endothelial cells2019
- Author(s)
  Koichi Sugimoto, Tetsuro Yokokawa, Tomofumi Misaka, Kazuhiko Nakazato, Takafumi Ishida, Yasuchika Takeishi
- Organizer
  第83回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] 治療に難渋しているcombined post- and pre-capillary PHの一例2019
- Author(s)
  中里和彦, 天海一明, 喜古崇豊, 菅野優紀, 山田慎哉, 及川雅啓, 杉本浩一, 竹石恭知
- Organizer
  第4回日本肺高血圧・肺循環学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] JAK2 V617F mutation promotes hypoxia-induced pulmonary hypertension in mice2019
- Author(s)
  Yusuke Kimishima, Tomofumi Misaka, Tetsuro Yokokawa, Keiji Minakawa, Koichi Sugimoto, Takafumi Ishida, Kazuhiko Ikeda, Yasuchika Takeishi
- Organizer
  XXIII ISHR World Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] Balloon pulmonary angioplasty improves electrocardiographic remodeling of the right ventricle in patients with chronic thromboembolic pulmonary hypertension2018
- Author(s)
  Yokokawa T, Sugimoto K, Nakazato K, Oikawa M, Kobayashi A, Yoshihisa A, Yamaki T, Kunii H, Ishida T, Takeishi Y
- Organizer
  Scientific Sessions of American Heart Association 2018, Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] Senescence marker protein 30 affects phosphorylation of endothelial nitric oxide synthase in hypoxia-induced pulmonary hypertension in mice2018
- Author(s)
  Sugimoto K, Sato A, Suzuki S, Yokokawa T, Misaka T, Nakazato K, Ishida T, Takeishi Y
- Organizer
  Scientific Sessions of American Heart Association 2018, Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] Impact of combined post capillary pulmonary hypertension based on upcoming diagnostic criteria on the prognosis of pulmonary hypertension due to left-sided heart disease2018
- Author(s)
  Sugimoto K, Yoshihisa A, Yokokawa T, Misaka T, Oikawa M, Kobayashi A, Yamaki T, Kunii H, Nakazato K, Ishida T, Takeishi Y
- Organizer
  Scientific Sessions of American Heart Association 2018, Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] Effect of endothelin-1 stimulation in the expression of activin receptor-like kinase-1 (ALK-1) in human pulmonary arterial endothelial cells2018
- Author(s)
  Sugimoto K, Kimishima Y, Misaka T, Nakazato K, Ishida T, Takeishi Y
- Organizer
  International Society for Heart Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] The fibrosis-4 index predicts the mortality of patients with pulmonary hypertension due to left sided-heart disease2018
- Author(s)
  Sugimoto K, Yoshihisa A, Goto T, Yokokawa T, Oikawa M, Kobayashi A, Nakazato K, Ishida T, Takeishi Y
- Organizer
  Scientific Sessions of American Heart Association 2018, Chicago, USA
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09516
[Presentation] Tenascin-C level is related to coronary plaque rupture in patients with acute coronary syndrome2011
- Author(s)
  Sakamoto N, Nakazato K, Mizukami H, Suzuki S, Sugimoto K, Yamaki T, Kunii H, Suzuki H, Saitoh S, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Acute benefical impact of adaptive servo ventilation on hemodynamic data in heart failure patients with Cheyne-Stokes respiration2011
- Author(s)
  Miyata M, Yoshihisa A, Sato T, Suzuki S, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improves cardiac function and prognosis in chronic heart failure patients with Cheyne-Stokes respiration after cardiac resynchronization therapy2011
- Author(s)
  Miyata M, Yoshihisa A, Suzuki S, Yamada S, Kamioka M, Kamiyama Y, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Orlando, Florida USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Overnight use of adaptive servo ventilation reduces cardiac overload and improves renal function in patients with chronic heart failure and Cheyne-Stokes respiration2011
- Author(s)
  Yoshihisa A, Suzuki S, Miyata M, Sato T, Yamaki T, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitho S, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Orlando, Florida USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Non-invasive detection of vascular dysfunction in sleep apnea syndrome by cardio-ankle vascular index and flow-mediated dilatation2011
- Author(s)
  Yoshihisa A, Miyata M, Sato T, Suzuki S, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improves cardiac function and long term prognosis in heart failure patients with Cheyne-Stokes respiration2011
- Author(s)
  Yoshihisa A, Miyata M, Sato T, Suzuki S, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Paris, France
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Elevated soluble lectin-like oxidized LDL receptor-1(LOX-1) in coronary circulation of patients with acute coronary syndrome2010
- Author(s)
  Kunii H, Hoshino Y, Misaka T, Mizukami H, Sakamoto N, Sugimoto K, Nakazato K, Fujita Y, Sawamura T, Ishibashi T, Takeishi Y.
- Organizer
  American College of Cardiology, 59th Annual Scientific Session
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] MT1-MMP forms a complex with Gi and regulates eNOS expression at posttranscriptional mechanism in oxidized LDL stimulated-endothelial cells2010
- Author(s)
  Sugimoto K, et al
- Organizer
  Scientific Sessions of American Heart Association 2010
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 高度石灰化を有する冠動脈病変における3D-SPECTICTCA fusion imagingの有用性2010
- Author(s)
  待井宏文, 杉本浩一, 他
- Organizer
  第20回日本心臓核医学会総会・学術大会
- Place of Presentation
  東京
- Year and Date
  2010-06-25
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 3D負荷心エコー法におけるArea Trackingはアデノシン誘発性心筋虚血診断に有用である2010
- Author(s)
  小林淳, 杉本浩一, 他
- Organizer
  第21回日本心エコー図学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] LOX-1 cooperates with renin-angiotensin system in monocyte adhesion-induced redox-sensitive and Ca^<2+> signaling pathways in endothelial cells2010
- Author(s)
  Sakamoto N, Sugimoto K, et al
- Organizer
  Congress of the European Society of Cardiology 2010
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] MT1-MMP forms a complex with L OX-1 and plays a crucial role in oxi dized LDL-induced endothelial dysfun ction via RhoA/Rac1 activation.2010
- Author(s)
  K. Sugimoto, T. Ishibashi, T. Sawamura, H. Uekita, H. Ohkawara, N. Inoue, Y. Takuwa, M. Shiomi, T. Teramoto, Y. Takeishi.
- Organizer
  第74回日本循環器学会学術集会
- Place of Presentation
  京都
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Pivotal role of receptor for advanced glycation end products(RAGE) in hyperlipidemia-dependent atherosclerosis and molecular regulation2010
- Author(s)
  Uekita H, Ishibashi T, Shiomi M, Sugimoto K, Ohkawara H, Kamioka M, Yamagishi S, Teramoto T, Koyama H, Ohtsuka S, Itabe H, Takeishi Y.
- Organizer
  20th World Congress of the International Society for Heart Research(ISHR)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Membrane Type I Matrix Metalloproteinase(MT1-MMP) mediates thrombin-induced RhoA/Rac1 activation and their downstream signaling in endothelial cells2010
- Author(s)
  Ando K, Ishibashi T, Ohkawara H, Sugimoto K, Sakamoto N, Okamoto Y, Takuwa Y, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] MT1-MMP controls Akt-dependent Fox01 activation in TNF-α-induced signaling pathways of endothelial cell apoptosis and haemostasis2010
- Author(s)
  Ohkawara H, Ishibashi T, Ando K, Sugimoto K, Sakamoto N, Uekita H, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 睡眠時無呼吸症候群(SAS)合併心疾患患者における心血管機能低下に関する検討:k-CAVI及び%FMDの有用性2010
- Author(s)
  義久精臣, 杉本浩一, 他
- Organizer
  第58回日本心臓病学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] β遮断薬や心臓再同期療法にてCheyne-stokes呼吸の加療は不要となるか?2010
- Author(s)
  義久精臣, 杉本浩一, 他
- Organizer
  第58回日本心臓病学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Soluble lectin-like oxidized LDL receptor-1 (LOX-1) and LOX index are useful biomarkers for vulnerable plaques2010
- Author(s)
  Misaka T, Sugimoto K, et al
- Organizer
  Scientific Sessions of American Heart Association 2010
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 心不全に合併するチェーンストーク呼吸の重症度: 123I-MIBG心筋シンチによる心臓交感神経機能の検討2010
- Author(s)
  義久精臣, 杉本浩一, 他
- Organizer
  第58回日本心臓病学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improves cardiac function and prognosis in heart failure patients with Cheyne-Stokes respiration2010
- Author(s)
  Yoshihisa A, Sato T, Suzuki S, Sugimoto K, Kunii H, Nakazato K, Suzuki H, Saitoh S, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 3D負荷心エコーによる心筋虚血診断:いずれのStrain Rate指標が虚血診断に最も有用か2010
- Author(s)
  高野真澄, 杉本浩一, 他
- Organizer
  日本超音波医学会第83回学術集会
- Place of Presentation
  京都
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improves cardiac function and prognosis in heart failure patients with Cheyne-Stokes respiration2010
- Author(s)
  義久精臣, 杉本浩一, 他
- Organizer
  第14回日本心不全学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] High circulating levels of tenascin-c were associated with coronary arterial calcification in patients with stable effort angina pectoris2010
- Author(s)
  Sakamoto N, Nakazato K, Kunii H, Misaka T, Mizukami H, Sugimoto K, Saitoh S, Ishibashi T, Takeishi Y.
- Organizer
  American College of Cardiology, 59th Annual Scientific Session
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Pivotal role of receptor for advanced glycation end products (RAGE) inhyperlipidemia- dependent atherosclerosis and molecular regulation2010
- Author(s)
  Uekita H, Sugimoto K, et al
- Organizer
  20th World Congress of the International Society for Heart Research (ISHR)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Membrane Type I Matrix Metalloproteinase (MT1-MMP) mediates thrombin-induced RhoA/Rac1 activation and their downstream signaling in endothelial cells2010
- Author(s)
  Ando K, Sugimoto K, et al
- Organizer
  Congress of the European Society of Cardiology 2010
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] MT1-MMP controls Akt-dependent Fox01 activation in TNF-α-induced signaling pathways of endothelial cell apoptosis and haemostasis2010
- Author(s)
  Ohkawara H, Sugimoto K, et al
- Organizer
  Scientific Sessions of American Heart Association 2010
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Nicorandil was effective for a patient with heart failure by aortic stenosis2010
- Author(s)
  清水竹史, 杉本浩一, 他
- Organizer
  第14回日本心不全学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improves cardiac pre and after load in heart failure patients with Cheyne-Stokes respiration2010
- Author(s)
  大和田卓史, 杉本浩一, 他
- Organizer
  第14回日本心不全学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] MT1-MMP forms a complex with LOX-1 and plays a crucial role in oxidized LDL-induced endothelial dysfunction via RhoA/Rac1 activation2010
- Author(s)
  K.Sugimoto, T.Ishibashi, T.Sawamura, H.Uekita, H.Ohkawara, N.Inoue, Y.Takuwa, M.Shiomi, T.Teramoto, Y.Takeishi
- Organizer
  第74回日本循環器学会学術集会
- Place of Presentation
  京都
- Year and Date
  2010-03-07
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] LOX-1 cooperates with renin-angiotensin system (RAS) in monocyteadhesion-induced redox-sensitive and Ca^<2+> signaling pathways in endothelial cells (ECs)2010
- Author(s)
  Sakamoto N, Sugimoto K, et al
- Organizer
  20th World Congress of the International Society for Heart Research (ISHR)
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] PGI2持続投与中にACTH単独欠損を合併したIPAHの1症例2010
- Author(s)
  杉本浩一, 中里和彦, 他
- Organizer
  第11回肺高血圧症治療研究会
- Place of Presentation
  東京
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] RhoA・Rac1活性化を介する酸化LD Lによる血管内皮細胞機能不全の新しい分子機序:MT1-MMPの関与2010
- Author(s)
  杉本浩一、石橋敏幸、沢村達也、上北洋徳、上岡正志、井上信孝、坂本信雄、大河原浩、多久和陽、寺本民夫、塩見雅志、竹石恭知
- Organizer
  日本心脈管作動物質学会
- Place of Presentation
  名古屋
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] RhoA-Rac1活性化を介する酸化LDLによる血管内皮細胞機能不全の新しい分子機序:MT1-MMPの関与2010
- Author(s)
  杉本浩一、石橋敏幸、沢村逹也、上北洋徳、上岡正志、井上信孝、坂本信雄、大河原浩、多久和陽、寺本民夫、塩見雅志、竹石恭知
- Organizer
  日本心脈管作動物質学会
- Place of Presentation
  名古屋
- Year and Date
  2010-02-05
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Membrane Type I Matrix Metalloproteinase(MT1-MMP)mediates thrombin-induced RhoA/Rac1 activation and their downstream events in endothelial cells2010
- Author(s)
  安藤勝也, 杉本浩一, 他
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 虚血性心疾患患者におけるArea Strain Rateを用いた誘発性局所拡張不全の同定2010
- Author(s)
  高野真澄, 杉本浩一, 他
- Organizer
  第21回日本心エコー図学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Crucial role of MT1-MMP in haemostasis and endothelial apoptosis in TNF-α-stimulated ECs2010
- Author(s)
  大河原浩, 杉本浩一, 他
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  横浜
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] LOX-1 cooperates with renin-angiotensin system in monocyte adhesion-induced redox-sensitive and Ca^<2+> signaling pathways in endothelial cells2010
- Author(s)
  Sakamoto N, Ishibashi T, Sugimoto K, Ohkawara H, Inoue N, Sawamura T, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Stockholm, Sweden
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] MT1-MMP forms a complex with Gi and regulates eNOS expression at posttranscriptional mechanism in oxidized LDL stimulated-endothelial cells2010
- Author(s)
  Sugimoto K, Ishibashi T, Ohkawara H, Uekita H, Takuwa Y, Kurabayashi M, Teramoto T, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Stretched foramen ovaleを介し短絡血流増大を来したEbstein奇形の一例2010
- Author(s)
  佐久間信子, 杉本浩一, 他
- Organizer
  第21回日本心エコー図学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2010-05-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Preventive effects of pravastatin on thrombin triggered vascular responses mediated via Akt/eNOS and RhoA/Rac1 signaling pathways in vivo in rats2010
- Author(s)
  大河原浩, 杉本浩一, 他
- Organizer
  第42回日本動脈硬化学会総会・学術集会
- Place of Presentation
  名古屋
- Year and Date
  2010-07-15
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improved Cheyne-Stokes respiration in heart failure patients after CRTD implanta2010
- Author(s)
  益田淳朗, 杉本浩一, 他
- Organizer
  第14回日本心不全学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-10-07
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] LOX-1 cooperates with renin-angiotensin system(RAS) in monocyte adhesion-induced redox-sensitive and Ca^<2+> signaling pathways in endothelial cells(ECs)2010
- Author(s)
  Sakamoto N, Ishibashi T, Sugimoto K, Ohkawara H, Sakamoto T, Inoue N, Sawamura T, Takeishi Y.
- Organizer
  20th World Congress of the International Society for Heart Research(ISHR)
- Place of Presentation
  Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] チェーン・ストーク呼吸(CSR)合併心不全患者におけるadaptive servo ventilation及び酸素療法の交感神経活性に対する効果の検討2010
- Author(s)
  義久精臣, 杉本浩一, 他
- Organizer
  第58回日本心臓病学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-09-17
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 睡眠時無呼吸症候群(SAS)患者における肝機能及び内皮機能障害に関する検討2010
- Author(s)
  義久精臣, 杉本浩一, 他
- Organizer
  第18回日本消化器関連学会週間Japan Digestive Disease Week(JDDW)2010
- Place of Presentation
  横浜
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Adaptive servo ventilation improves cardiac function and prognosis in heartfailure patients with Cheyne-Stokes respiration2010
- Author(s)
  Yoshihisa A, Sugimoto K, et al
- Organizer
  Scientific Sessions of American Heart Association 2010
- Place of Presentation
  Chicago, Illinois, USA
- Year and Date
  2010-11-13
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Soluble lectin-like oxidized LDL receptor-1(LOX-1) and LOX index are useful biomarkers for vulnerable plaques2010
- Author(s)
  Misaka T, Kunii H, Nakazato K, Mizukami H, Sakamoto N, Sugimoto K, Saitoh S, Sawamura T, Uchida K, Ishibashi T, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Chicago, Illinois, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Cooperation of MT1-MMP and LOX-1 for RhoA- and Rac1-dependent signaling pathways in oxidized LDL-mediated endothelial dysfunction2009
- Author(s)
  K.sugimoto, T.Ishibashi, T.Sawamura, H.Uekita, M.Kamioka, N.Inoue, M.Shiomi, Y.Takuwa, T.Teramoto, Y.Takeishi
- Organizer
  Scientific Sessions of American Heart Association 2009
- Place of Presentation
  オーランド(アメリカ合衆国)
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Silencing of MT1-MMP Blocks Ox-LDL-Induced Rac1/NADPH Oxidas e Activity and Reactive Oxygen Specie s (ROS) Generation.2009
- Author(s)
  K. Sugimoto, T. Ishibashi, N. Inoue, Y. Takuwa, T. Teramoto, Y. Takeishi.
- Organizer
  第41回日本動脈硬化学会学術総会
- Place of Presentation
  下関
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Cooperation of MT1-MMP and LOX-1 for RhoAand Rac1-dependent signaling pathways in oxidized LDL-mediated endothelial dysfunction.2009
- Author(s)
  K. Sugimoto, T. Ishibashi, T. Sawamura, H. Uekita, M. Kamioka, N. Inoue, M. Shiomi, Y. Takuwa, T. Teramoto, Y. Takeishi.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  オーランド
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Akt cooperates with membrane type 1-matrix metalloproteinase(MT1-MMP) in TNF-α-induced signaling pathways of endothelial dysfunction and haemostasis2009
- Author(s)
  Ohkawara H, Ishibashi T, Ando K, Sugimoto K, Uekita H, Sakamoto N, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Membrane type matrix metalloprotainase-1 (MT1-MMP) is a cell surface modifier of RhoA/Rac1 -mediated signaling pathways and forms a complex with LOX-1 in oxidized LDL-induced endothelial dysfunction.2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Kamioka M, Uekita H, Ohkawara H, Inoue N, Takuwa Y, Teramoto T, Takeishi Y.
- Organizer
  Europian Society of Carciology Cogress 2009
- Place of Presentation
  バルセロナ
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] New insights of LOX-1-MT1-MMP Axis into RhoA and Rac1 Activation Induced by Oxidized Low-Density Lipoprotein in Endothelial Cells2009
- Author(s)
  K.Sugimoto, T.Ishibashi, T.Sawamura, H.Uekita, Y.Takuwa, T.Teramoto, M.Shiomi, Y.Takeishi
- Organizer
  Basic Cardiovascular Sciences Conference 2009, American Heart Association
- Place of Presentation
  ヘンダーソン(アメリカ合衆国)
- Year and Date
  2009-07-20
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Membrane type matrix metalloproteinase-1(MT1-MMP) is a cell surface modifier of RhoA/Rac1-mediated signaling pathways and forms a complex with LOX-1 in oxidized LDL-induced endothelial dysfunction2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Kamioka M, Uekita H, Ohkawara H, Inoue N, Takuwa Y, Teramoto T, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 酸化LDLによる血管内皮と機能不全におけるLOX-1/MT1-MMP系の役割2009
- Author(s)
  杉本浩一、石橋敏幸、竹石恭知
- Organizer
  第1回 Advance研究会
- Place of Presentation
  名古屋
- Year and Date
  2009-12-26
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Silencing of MT1-MMP Blocks Ox-LDL-Induced Rac1/NADPH Oxidase activity and Reactive Oxygen Species (ROS) Generation2009
- Author(s)
  K.Sugimoto, T.Ishibashi, N.Inoue, Y.Takuwa, T.Teramoto, Y.Takeishi
- Organizer
  第41回日本動脈硬化学会学術総会
- Place of Presentation
  下関
- Year and Date
  2009-07-17
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Integral role of receptor for advanced glycation end products(RAGE) in nondiabetic atherosclerosis2009
- Author(s)
  Uekita H, Ishibashi T, Sugimoto K, Shiomi M, Yamagishi S, Koyama H, Takeishi Y.
- Organizer
  Basic Cardiovascular Sciences Conference 2009-Molecular Mechanisms of Cardiovascular Disease
- Place of Presentation
  Lake Las Vegas, Nevada, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] New insights of LOX-1-MT1-MMP axis into RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Uekita H, Takuwa Y, Teramoto T, Shiomi M, Takeishi Y.
- Organizer
  Basic Cardiovascular Sciences Conference 2009-Molecular Mechanisms of Cardiovascular Disease
- Place of Presentation
  Lake Las Vegas, Nevada, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Crucial role of LOX-1 in monocyte adhesion-triggered NADPH oxidase-dependent, Akt/eNOS and Ca^<2+> signaling pathways in endothelial cells2009
- Author(s)
  Sakamoto N, Ishibashi T, Sugimoto K, Sawamura T, Sakamoto T, Ohkawara H, Saitoh S, Inoue N, Teramoto T, Takeishi Y.
- Organizer
  Congress of the European Society of Cardiology
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] New insights of LOX-1-MT1-MMP Axis into RhoA and Rac1 Activation Induced by Oxidized Low-Density Lipoprotein in Endothelial Cells.2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Uekita H, Takuwa Y, Teramoto T, Shiomi M, Takeishi Y.
- Organizer
  Basic Cardiovascular Sciences Conference 2009
- Place of Presentation
  ヘンダーソン
- Year and Date
  2009-07-20
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] LOX-1 mediates renin-angiotensin system(RAS)-dependent redox-sensitive and Ca^<2+> signaling pathways induced in endothelial cells by monocyte adhesion2009
- Author(s)
  Sakamoto N, Ishibashi T, Sugimoto K, Sakamoto T, Ohkawara H, Sawamura T, Inoue N, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] 酸化LDLによる血管内皮機能不全におけるLOX-1/MT1-MMP系の役割2009
- Author(s)
  杉本浩一、石橋敏幸、竹石恭知
- Organizer
  第1回Advance研究会
- Place of Presentation
  名古屋
- Year and Date
  2009-12-26
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Cooperation of MT1-MMP and LOX-1 for RhoA-and Rac1-dependent signaling pathways in oxidized LDL-mediated endothelial dysfunction and atherosclerosis2009
- Author(s)
  Sugimoto K, Ishibashi T, Sawamura T, Uekita H, Kamioka M, Inoue N, Shiomi M, Takuwa Y, Teramoto T, Takeishi Y.
- Organizer
  Scientific Sessions of American Heart Association
- Place of Presentation
  Orlando, Florida, USA
- Data Source
  KAKENHI-PROJECT-22790718
[Presentation] Membrane type matrix metalloprotainase-1 (MT1-MMP) is a cell surface modifier of RhoA/Rac1-mediated signaling pathways and forms a complex with LOX-1 in oxidized LDL-induced endothelial dysfunction.2009
- Author(s)
  K.Sugimoto, T.Ishibashi, T.Sawamura, M.Kamioka, H.Uekita, H.Ohkawara, N.Inoue, Y.Takuwa, T.Teramoto, Y.Takeishi
- Organizer
  Congress of the European Society of Cardiology 2009
- Place of Presentation
  バルセロナ(スペイン)
- Year and Date
  2009-08-29
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] LOX-1-MT1-MMP Axis in RhoA and Racl activation through Gi induced by oxidizes low-density lipoprotein in endothelial cells2008
- Author(s)
  杉本浩一
- Organizer
  第16回日本血管生物医学会学術集会
- Place of Presentation
  金沢
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20790538
[Presentation] Lox-1-MT1-MMP系は酸化LDL刺激血管内皮細胞においてGiを介するRhoA, Raclの活性化に重要である2008
- Author(s)
  杉本浩一
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  筑波
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-20790538

1. Nakazato Kazuhiko (90363762)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. 三阪智史 (50793080)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 小林淳 (20448640)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 鈴木聡 (60536944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 横川哲朗 (80748773)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 石田隆史 (40346482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YOSHIHISA Akiomi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 池田和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sugimoto Koichi 杉本 浩一

杉本 浩一 スギモト コウイチ

SUGIMOTO Koichi 杉本 浩一

Research Projects

Research Products

Co-Researchers

肺動脈性肺高血圧症の内皮間葉分化転換におけるDNA損傷応答とTGF-βの役割Principal Investigator

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Study on the difference of severity and treatment response of pulmonary hypertension

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Effects of high-fat diet on pulmonary hypertension and role of MT1-MMP as a biomarkerPrincipal Investigator

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Study on diagnosis and treatment effect evaluation of pulmonary hypertension by biomarker and imaging modality

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The novel molecular mechanism of membrane type1 matrix metallo proteinase(MT1-MMP) in vascular inflammationPrincipal Investigator

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Role of LOX-1-MT1-MMP axis in oxidized LDL-triggered endothelial dysfunctionPrincipal Investigator

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[Journal Article] Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils2021

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[Journal Article] Pulmonary Hypertension and Hereditary Hemorrhagic Telangiectasia Related to an <i>ACVRL1</i> Mutation2020

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[Journal Article] Significance of Pulmonary Vascular Resistance and Diastolic Pressure Gradient on the New Definition of Combined Post-Capillary Pulmonary Hypertension2020

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[Journal Article] Senescence Marker Protein 30 Deficiency Exacerbates Pulmonary Hypertension in Hypoxia-Exposed Mice2019

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[Journal Article] Soluble neprilysin does not correlate with prognosis in pulmonary hypertension2019

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[Journal Article] Electrocardiographic Criteria of Right Ventricular Hypertrophy in Patients with Chronic Thromboembolic Pulmonary Hypertension after Balloon Pulmonary Angioplasty2019

Sugimoto Koichi 杉本浩一

杉本浩一スギモトコウイチ

SUGIMOTO Koichi 杉本浩一