Tadagaki Kenjiro 忠垣憲次郎

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TADAGAKI KENJIRO 忠垣憲次郎

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Researcher Number	30416268
Other IDs
Affiliation (Current)	2025: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Affiliation (based on the past Project Information) *help	2024: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2016 – 2021: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2014: 京都府立医科大学, 医学(系)研究科(研究院), 助教 2013: 大阪大学, 医学(系)研究科(研究院), 特任助教(常勤)
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related / Basic Section 54010:Hematology and medical oncology-related / Hematology / General pharmacology
Keywords	Principal Investigator RUNX1 / 転写因子 / 遺伝子発現 / プロモーター / Runx1 / 造血幹細胞 / 遺伝子発現制御 / 標的遺伝子 / トランスポーター / アミノ酸トランスポーター / シグナル伝達 / 薬理学

Elucidation of regulation of expression of hematopoietic transcription factor RUNX1 and application to development of new treatmentsPrincipal Investigator
- Principal Investigator
  
  忠垣憲次郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kyoto Prefectural University of Medicine
Elucidation of cell differentiation by hematopoietic transcription factor RUNX1 and translation to a novel molecular target strategyPrincipal Investigator
- Principal Investigator
  
  TADAGAKI Kenjiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Kyoto Prefectural University of Medicine
Regulation mechanisms of hematopoietic transcription factor RUNX1 through the transcription network analysesPrincipal Investigator
- Principal Investigator
  
  TADAGAKI KENJIRO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kyoto Prefectural University of Medicine
mTOR signaling mechanisms dependent on amino acid transporterPrincipal Investigator
- Principal Investigator
  
  TADAGAKI KENJIRO
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kyoto Prefectural University of Medicine
  Osaka University

All 2022 2021 2020 2019 2018 2017 2016 2014

All Journal Article Presentation

[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022
- Author(s)
  Matsumoto Akifumi、Yoshida Tatsushi、Shima Takahiro、Yamasaki Kenta、Tadagaki Kenjiro、Kondo Noriko、Kuwahara Yasumichi、Zhang Dong-Er、Okuda Tsukasa
- Journal Title
  
  BBA Advances
  
  Volume: 2 Pages: 100047-100047
- DOI
  10.1016/j.bbadva.2022.100047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846
[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 12022
- Author(s)
  Yoshida Tatsushi、Yamasaki Kenta、Tadagaki Kenjiro、Kuwahara Yasumichi、Matsumoto Akifumi、Sofovic Adem、Kondo Noriko、Sakai Toshiyuki、Okuda Tsukasa
- Journal Title
  
  International Journal of Oncology
  
  Volume: 60 Issue: 1 Pages: 1-1
- DOI
  10.3892/ijo.2021.5296
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08845, KAKENHI-PROJECT-19K08846, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079
[Journal Article] The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development.2018
- Author(s)
  Wojciech S, Ahmad R, Belaid-Choucair Z, Journe AS, Gallet S, Dam J, Daulat A, Ndiaye-Lobry D, Lahuna O, Karamitri A, Guillaume JL, Do Cruzeiro M, Guillonneau F, Saade A, Clement N, Courivaud T, Kaabi N, Tadagaki K, Delagrange P, Prevot V, Hermine O, Prunier C, Jockers R.
- Journal Title
  
  Nature Communications
  
  Volume: 9 (1) Issue: 1 Pages: 1216-1216
- DOI
  10.1038/s41467-018-03609-x
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09857
[Journal Article] Systematic protein-protein interaction mapping for clinically relevant human GPCRs.2017
- Author(s)
  Sokolina K, Kittanakom S, Snider J, Kotlyar M, Maurice P, Gandia J, Benleulmi-Chaachoua A, Tadagaki K, Oishi A, Wong V, Malty RH, Deineko V, Aoki H, Amin S, Yao Z, Morato X, Otasek D, Kobayashi H, Menendez J, Auerbach D, Angers S, Przulj N, Bouvier M, Babu M, Ciruela F, Jockers R, Jurisica I, Stagljar I.
- Journal Title
  
  Molecular Systems Biology
  
  Volume: 13(3) Issue: 3
- DOI
  10.15252/msb.20167430
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09857
[Journal Article] Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50.2017
- Author(s)
  Clement N, Renault N, Guillaume JL, Cecon E, Journe AS, Laurent X, Tadagaki K, Coge F, Gohier A, Delagrange P, Chavatte P, Jockers R.
- Journal Title
  
  British Journal of Pharmacology
  
  Volume: - Issue: 16 Pages: 3281-3297
- DOI
  10.1111/bph.14029
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.2021
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第８０回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] 造血制御転写因子 RUNX1 標的遺伝子の解析2021
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康通、近藤則子、松本晃典、酒井敏行、奥田司
- Organizer
  第１１回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] DNAメチル化プロファイルを用いたラブロイド腫瘍患者の同時多発病変より樹立した新規２細胞株の解析2020
- Author(s)
  桒原康通、家原知子、勝見良樹、土屋邦彦、宮地充、田尻達郎、忠垣憲次郎、吉田達士、奥田司、細井創
- Organizer
  第７９回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] クロマチンリモデリング因子研究におけるラブドイド腫瘍細胞株の有用性2020
- Author(s)
  桒原康道、近藤則子、忠垣憲次郎、山崎健太、吉田達士、奥田司
- Organizer
  第２４回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019
- Author(s)
  山崎健太、忠垣憲次郎、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第４２回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] 転写因子RUNX1/AML1の新規候補標的遺伝子群の探索2019
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第９２回日本生化学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO.2019
- Author(s)
  Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Donger Zhang, Tsukasa Okuda
- Organizer
  第８１回日本血液学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] Analysis of a novel transcriptional target gene of RUNX1.2019
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Yasumichi Kuwahara, Toshiyuki Sakai, Tsukasa Okuda.
- Organizer
  第７８回日本癌学会
- Data Source
  KAKENHI-PROJECT-19K08845
[Presentation] SWI/SNFクロマチンリモデリング因子と造血系転写因子の機能調節2019
- Author(s)
  桒原康道、近藤則子、忠垣憲次郎、山崎健太、吉田達士、奥田司
- Organizer
  第２３回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Analysis of a novel candidate target gene of the hematopoietic transcription factor RUNX1 (AML1).2018
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Noriko Kondo, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第８０回日本血液学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] クロマチンリモデリング因子SNF5と細胞の腫瘍化2018
- Author(s)
  桒原康道、近藤則子、忠垣憲次郎、山崎健太、吉田達士、奥田司
- Organizer
  第２２回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A novel transcription factor RUNX1.2018
- Author(s)
  Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Yasumichi Kuwahara, Noriko Kondo,　Akifumi Matsumoto, Toshiyuki Sakai, Tsukasa Okuda.
- Organizer
  第９１回日本生化学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] 急性骨髄性白血病におけるRUNX1新規標的遺伝子の同定2018
- Author(s)
  松本晃典、吉田達士、山崎健太、忠垣憲次郎、桒原康道、近藤則子、奥田司
- Organizer
  平成３０年度第８回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Functional interaction between SWI/SNF complex and a hematopoietic transcription factor in malignant rhabdoid tumor.2018
- Author(s)
  Yasumichi Kuwahara, Tatsushi Yoshida, Kenjiro Tadagaki, Tsukasa Okuda.
- Organizer
  第７７回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] 造血関連転写因子RUNX1(AML1)の新規転写標的候補遺伝子の探索2018
- Author(s)
  忠垣憲次郎、山崎健太、近藤則子、桒原康通、吉田達士、奥田司
- Organizer
  第４１回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] 白血病由来RUNX1遺伝子変異体における機能的異常の解析2017
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、近藤則子、奥田司
- Organizer
  平成２９年度第７回４大学連携研究フォーラム
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Mechanism of recruitment of SWI/SNF complex via interaction between SNF5 and transcription factor.2017
- Author(s)
  Yasumichi Kuwahara, Kenta Yamasaki, Kenjiro Tadagaki, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Candidate target genes of hematopoietic transcription factor RUNX1 (AML1).2017
- Author(s)
  Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第７９回日本血液学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1/AML1転写因子の新規候補標的遺伝子の解析2017
- Author(s)
  忠垣憲次郎、山崎健太、桒原康道、吉田達士、奥田司
- Organizer
  第６４回日本生化学会近畿支部例会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1によるTRAIL遺伝子の転写制御機構2017
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、酒井敏行、奥田司
- Organizer
  第21回造血器腫瘍研究会
- Place of Presentation
  熊本大学（熊本市）
- Year and Date
  2017-02-17
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] An array-based approach for novel RUNX1(AML1)-target genes.2017
- Author(s)
  Kenjiro Tadagaki, Yasumichi Kuwahara, Tatsushi Yoshida, Tsukasa Okuda.
- Organizer
  第７６回日本癌学会
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A natural inhibitor of Runt-related Transcription Factor 1 / Acute Myeloid Leukemia 1 (RUNX1/AML1).2016
- Author(s)
  Tatsushi Yoshida, Kenta Yamasaki, Kenjiro Tadagaki, Yasumichi Kuwahara, Tsukasa Okuda.
- Organizer
  第89回日本生化学会
- Place of Presentation
  東北大学（仙台市）
- Year and Date
  2016-09-26
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] 白血病関連転写因子の制御法の開発と白血病治療に向けた応用2016
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康道、奥田司
- Organizer
  平成28年度第6回4大学連携研究フォーラム
- Place of Presentation
  京都薬科大学（京都市）
- Year and Date
  2016-12-07
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] RUNX1/AML1はTRAILの転写制御に関与する2016
- Author(s)
  吉田達士、山崎健太、忠垣憲次郎、桒原康通、酒井敏行、奥田司
- Organizer
  第39回日本分子生物学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] A candidate target gene of RUNX1/AML1 transcription factor.2016
- Author(s)
  Tatsushi Yoshida, Kenjiro Tadagaki, Kenta Yamasaki, Yasumichi Kuwahara, Toshiyuki Sakai, Tsukasa Okuda.
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（横浜市）
- Year and Date
  2016-10-14
- Data Source
  KAKENHI-PROJECT-16K09857
[Presentation] Inhibition of cancer-type amino acid transporter LAT1 affects multiple cellular events in pancreatic cancer cells.2014
- Author(s)
  Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
- Organizer
  The 126th Meeting of Japanese Pharmacological Society Kinki Branch
- Place of Presentation
  和歌山県JAビル（和歌山市）
- Year and Date
  2014-10-24
- Data Source
  KAKENHI-PROJECT-25860189
[Presentation] Transport mechanisms of 4-borono-phenylalanine as a 10B carrier of boron neutron capture therapy for cancers.2014
- Author(s)
  Printip Wongthai, Kohei Hagiwara, Yurika Miyoshi, Pattama Wiriyasermkul, Pornparn Kongpracha, Isozumi Noriyoshi1, Ryuichi Ohgaki, Kenjiro Tadagaki, Kenji Hamase, Shushi Nagamori, Yoshikatsu Kanai
- Organizer
  The 61th Japanese Biochemical Society Kinki Branch
- Place of Presentation
  京都産業大学（京都市北区）
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25860189
[Presentation] Study of a cellular signaling network stimulated with leucine transported by a cancer-type amino acid transporter LAT1.2014
- Author(s)
  Pornparn Kongprach, Pattama Wiriyasermkul, Noriyoshi Isozumi, Printip Wongthai, Suguru Okuda, Kenjiro Tadagaki, Ryuichi Ohgaki, Shushi Nagamori, Yoshikatsu Kanai
- Organizer
  The 61th Japanese Biochemical Society Kinki Branch
- Place of Presentation
  京都産業大学（京都市北区）
- Year and Date
  2014-05-17
- Data Source
  KAKENHI-PROJECT-25860189

1. 奥田司 (30291587)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results

Tadagaki Kenjiro 忠垣 憲次郎

TADAGAKI KENJIRO 忠垣 憲次郎

Research Projects

Research Products

Co-Researchers

Elucidation of regulation of expression of hematopoietic transcription factor RUNX1 and application to development of new treatmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of cell differentiation by hematopoietic transcription factor RUNX1 and translation to a novel molecular target strategyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation mechanisms of hematopoietic transcription factor RUNX1 through the transcription network analysesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

mTOR signaling mechanisms dependent on amino acid transporterPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tumor necrosis factor-related apoptosis-inducing ligand is a novel transcriptional target of runt-related transcription factor 12022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The orphan GPR50 receptor promotes constitutive TGFβ receptor signaling and protects against cancer development.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Systematic protein-protein interaction mapping for clinically relevant human GPCRs.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Importance of the second extracellular loop for melatonin MT1 receptor function and absence of melatonin binding in GPR50.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] A seaweed-derived compound that inhibits growth of acute myeloid leukemia cells.2021

Author(s)

Organizer

Data Source

[Presentation] 造血制御転写因子 RUNX1 標的遺伝子の解析2021

Author(s)

Organizer

Data Source

[Presentation] DNAメチル化プロファイルを用いたラブロイド腫瘍患者の同時多発病変より樹立した新規２細胞株の解析2020

Author(s)

Organizer

Data Source

[Presentation] クロマチンリモデリング因子研究におけるラブドイド腫瘍細胞株の有用性2020

Author(s)

Organizer

Data Source

[Presentation] 造血関連転写因子 RUNX1による制御遺伝子の探索2019

Author(s)

Organizer

Data Source

[Presentation] 転写因子RUNX1/AML1の新規候補標的遺伝子群の探索2019

Author(s)

Organizer

Data Source

[Presentation] Identification of a novel RUNX1 target by public data re-analysis that is suppressed by RUNX1-ETO.2019

Author(s)

Tadagaki Kenjiro 忠垣憲次郎

TADAGAKI KENJIRO 忠垣憲次郎