Noguchi Ryuichi 野口隆一

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NOGUCHI Ryuuichi 野口隆一

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Researcher Number	30423908
Affiliation (Current)	2025: 奈良県立医科大学, 医学部附属病院, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2019: 奈良県立医科大学, 医学部附属病院, 研究員 2015: 奈良県立医科大学, 医学部, 講師 2012 – 2015: 奈良県立医科大学, 医学部, 助教 2011: 奈良県立医科大学, 医学部附属病院, 研究員 2010: 奈良県立医科大学, 医学部, 特任助教 2008 – 2009: 奈良県立医科大学, 医学部, 博士研究員
Review Section/Research Field	Principal Investigator Gastroenterology Except Principal Investigator Gastroenterology / Medical pharmacy
Keywords	Principal Investigator 肝線維化 / NASH / 腸肝相関 / equal / 腸内細菌 / equol / エクオール / 血管新生 / DPPⅣ阻害剤 / DPPIV阻害剤 … More / 非アルコール性脂肪肝炎 / PAI-1 / DPP4阻害剤 / PAI-1阻害剤 / SGLT-2阻害剤 / DPP-Ⅳ阻害剤 / ARB / 生活習慣病 … More Except Principal Investigator 肝癌 / 肝線維化 / 血管新生 / ウルソデオキシコール酸 / farnesoid X receptor / FXR / OCT1 / 胆汁酸 / カクテル療法 / 慢性肝疾患 / 肝硬変 / レニンアンジオテンシン系 / インスリン抵抗性 / アンジオテンシン / 肝発癌 / VEGF / 肝臓学 Less

Therapeutic effect of Equol on gut microbiome - mediated NASH progressionPrincipal Investigator
- Principal Investigator
  
  NOGUCHI RYUICHI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Identification of novel treatment and biomarkers based on pharmacokinetics in patients with hepatocellular carcinoma
- Principal Investigator
  
  Namisaki Tadashi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Nara Medical University
Establishment of new treatment targeting lifestyle diseases and coagulation fibrinolytic system related to the development of NASHPrincipal Investigator
- Principal Investigator
  
  Noguchi Ryuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Establishment of new therapy for chronic liver diseases progression
- Principal Investigator
  
  YOSHIJI Hitoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University
Crosstalk of renin-angiotensin system in the chronic liver diseases and therapeutic applications
- Principal Investigator
  
  YOSHIJI Hitoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Nara Medical University

All 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008

All Journal Article Presentation Book

[Book] The Liver Cancer Journal2016
- Author(s)
  野口隆一
- Publisher
  メディカルレビュー
- Data Source
  KAKENHI-PROJECT-26461018
[Book] Annual Review 2016 消化器2016
- Author(s)
  野口隆一、吉治仁志
- Total Pages
  7
- Publisher
  中外医学
- Data Source
  KAKENHI-PROJECT-26461018
[Book] 消化器病学の進歩-原点から未来への情報発信-(血管新生因子VEGFを標的とした肝癌再発抑制:ACE阻害剤、ビタミンK併用療法の臨床的検討)2009
- Author(s)
  吉治仁志、野口隆一、福井博
- Total Pages
  206
- Publisher
  日本消化器病学会
- Data Source
  KAKENHI-PROJECT-20590792
[Book] 消化器疾患におけるエピゲノミクスとゲノミクス(血管新生因子VEGFに対する既存薬剤を用いた分子標的治療の試み:インスリン抵抗性条件下での肝発癌に対するBCAAの効果)2009
- Author(s)
  吉治仁志、鍛治孝祐、北出光輝、池中康英、野口隆一、吉井純一、簗瀬公嗣、山崎正晴、浪崎正、福井博
- Total Pages
  135
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-20590792
[Book] 肝胆膵(レニン・アンジオテンシン系阻害薬)2009
- Author(s)
  吉治仁志、野口隆一、福井博
- Total Pages
  313
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-20590792
[Book] 慢性肝疾患日本臨床2009
- Author(s)
  吉治仁志、野口隆一、福井博
- Total Pages
  799
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-20590792
[Book] 肝胆膵(血管新生阻害剤の新しい展開「肝癌」)2009
- Author(s)
  吉治仁志、野口隆一、福井博
- Total Pages
  307
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Effect of combined farnesoid X receptor agonist and angiotensin Ⅱtipe 1 receptor blocker on hepatic fibrosis.2017
- Author(s)
  Namisaki T. Moriya K, Kitade M, Takeda K, Kaji K, Okura Y, Shimozato N. Sato S, Nishimura N, Seki K, Kawaratani H, Takaya H, Sawada Y, Akahane T, Saikawa S, Nakanishi K, Kubo T, Furukawa M, Noguchi R, Asada K, Kitagawa K, Ozutsumi T, Tsuji Y, Kaya H Yoshiji
- Journal Title
  
  Hepatol commun.
  
  Volume: 1 Issue: 9 Pages: 928945-928945
- DOI
  10.1002/hep4.1104
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09438, KAKENHI-PROJECT-15K08077
[Journal Article] Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis.2016
- Author(s)
  Okura Y,Yoshiji H.
- Journal Title
  
  Hepatol Res
  
  Volume: Dec28 Issue: 12 Pages: 1317-1328
- DOI
  10.1111/hepr.12860
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461017, KAKENHI-PROJECT-26461018, KAKENHI-PROJECT-15K08077
[Journal Article] DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis.2016
- Author(s)
  Asada K, Aihara Y, Takaya H, Noguchi R, Namisaki T, Moriya K, Uejima M, Kitade M, Mashitani T, Takeda K, Kawaratani H, Okura Y, Kaji K, Douhara A, Sawada Y, Nishimura N, Seki K, Mitoro A, Yamao J, Yoshiji H.
- Journal Title
  
  World J Hepatol.
  
  Volume: 8 Issue: 28 Pages: 1194-1194
- DOI
  10.4254/wjh.v8.i28.1194
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis.2016
- Author(s)
  Namisaki T, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Nishimura N, Takeda K, Okura Y, Kawaratani H, Takaya H, Seki K, Yoshiji H.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 51 Pages: 162-172
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Efficacy of alogliptin in preventing non-alcoholic fatty liver disease progression in patients with type 2 diabetes.2016
- Author(s)
  Mashitani T, Noguchi R, Okura Y, Namisaki T, Mitoro A, Ishii H, Nakatani T, Kikuchi E, Moriyasu H, Matsumoto M, Sato S, An T, Morita H, Aizawa S, Tokuoka Y, Ishikawa M, Matsumura Y, Ohira H, Kogure A, Noguchi K, Yoshiji H.
- Journal Title
  
  Biomed Rep.
  
  Volume: 4 Pages: 183-187
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Beneficial effects of combined ursodeoxycholic acid and angiotensin-II type 1 receptor blocker on hepatic fibrogenesis in a rat model of nonalcoholic steatohepatitis.2016
- Author(s)
  Namisaki T, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Nishimura N, Takeda K, Okura Y, Kawaratani H, Takaya H, Seki K, Yoshiji H
- Journal Title
  
  Ｊｏｕｎａｌ　ｏｆ　Ｇａｓｔｒｏｅｎｔｅｒｏｌｏｇｙ
  
  Volume: ５１ Issue: 2 Pages: 162-72
- DOI
  10.1007/s00535-015-1104-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08077, KAKENHI-PROJECT-26461017
[Journal Article] Ipragliflozin, a sodium-glucose cotransporter 2 inhibitor, ameliorates the development of liver fibrosis in diabetic Otsuka Long-Evans Tokushima fatty rats.2016
- Author(s)
  Nishimura N, Kitade M, Noguchi R, Namisaki T, Moriya K, Takeda K, Okura Y, Aihara Y, Douhara A, Kawaratani H, Asada K, Yoshiji H.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Reduction of endotoxin attenuates liver fibrosis through suppression of hepatic stellate cell activation and remission of intestinal permeability in a rat non-alcoholic steatohepatitis model.2015
- Author(s)
  Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Kaji K, Aihara Y, Nishimura N, Takeda K, Okura Y, Kawaratani H, Fukui H.
- Journal Title
  
  Mol Med Rep.
  
  Volume: 11 Pages: 1693-1700
- NAID
  40020982272
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461018
[Journal Article] Direct renin inhibitor, aliskiren, attenuates the progression of non-alcoholic steatohepatitis in the rat model.2013
- Author(s)
  Aihara Y, Yoshiji H et al
- Journal Title
  
  Hepatol Res.
  
  Volume: 43 Issue: 11 Pages: 1241-1250
- DOI
  10.1111/hepr.12081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Dual blockade of angiotensin-IIand aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis2013
- Author(s)
  Noguchi R, Yoshiji H, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Namisaki T, Kitade M, Douhara A, Moriya K, Fukui H
- Journal Title
  
  Hepatology Research
  
  Volume: 43(7) Pages: 765-774
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Dual blockade of angiotensin-IIand aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis2013
- Author(s)
  Noguchi R, Yoshiji H et al
- Journal Title
  
  Hepatology Research
  
  Volume: 43 Issue: 7 Pages: 765-774
- DOI
  10.1111/hepr.12008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Branched-chain amino acids suppress the cumulative recurrence of hepatocellular carcinoma under conditions of insulin-resistance2013
- Author(s)
  Yoshiji H, Noguchi R, Namisaki T, Moriya K, Kitade M, Aihara Y, Douhara A, Yamao J, Fujimoto M, Toyohara M, Mitoro A, Sawai M, Yoshida M, Morioka C, Uejima M, Uemura M, Fukui H
- Journal Title
  
  Oncology Reports
  
  Volume: 30 Pages: 545-552
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Cross talk between toll-like receptor-4 signaling and angiotensin-IIin liver fibrosis development in the rat model of non-alcoholic steatohepatitis2013
- Author(s)
  Shirai Y, Yoshiji H, Noguchi R, Kaji K, Aihara Y, Douhara A, Moriya K, Namisaki T, Kawaratani H, Fukui H
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 28(4) Pages: 723-30
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Dual blockade of angiotensin-II and aldosterone suppresses the progression of a non-diabetic rat model of steatohepatitis.2012
- Author(s)
  Noguchi R, Yoshiji H, et al.
- Journal Title
  
  Hepatol Res.
  
  Volume: Nov 20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Possible involvement of angiogenesis in chronic liver diseases : Interaction among renin-angiotensin-aldosterone system, Insulin resistance and oxidative stress2012
- Author(s)
  Yoshiji H, Ikenaka Y, Noguchi R, Aihara Y, Shirai Y, Douhara A, Fukui H, Kaji K
- Journal Title
  
  Current Medicinal Chemistry
  
  Volume: 19(12) Pages: 1889-1898
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor improves liver fibrosis progression in patients with cirrhosis2012
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Douhara A, Yamao J, Toyohara M, Mitoro A, Sawai M, Yoshida M, Morioka C, Fujimoto M, Uemura M, Fukui H
- Journal Title
  
  Molecular Medicine Reports
  
  Volume: 5 Pages: 539-544
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Impact of Renin-angiotensin system in hepatocellular carcinoma2011
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Fukui H
- Journal Title
  
  Current Cancer Drug Targets
  
  Volume: 11(4) Pages: 431-441
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Combination treatment of angiotensinIItypeIreceptor blocker and new oral iron chelator attenuates progression of nonalcoholic steatohepatitis in rats2011
- Author(s)
  Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Shirai Y, Aihara Y, Namisaki T, Yoshii J, Yanase K, Tsujimoto T, Kawaratani H, Fukui H
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol
  
  Volume: 300 Pages: 1094-1104
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Cocktail therapy with a combination of interferon, ribavirin and angiotensin-II type 1 receptor blocker attenuates murine liver fibrosis development.2011
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Yoshii J, Yanase K, Fukui H.
- Journal Title
  
  Int J Mol Med.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Soluble VEGF receptor-2 may be a predictive marker of anti-angiogenic therapy with clinically available safe agents2011
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Shirai Y, Aihara Y, Yamao J, Toyohara M, Mitoro A, Sawai M, Yoshida M, Morioka C, Fujimoto M, Uemura M, Kawaratani H, Tsujimoto T, Fukui H
- Journal Title
  
  Oncology Letters
  
  Volume: 2 Pages: 69-73
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Cocktail therapy with a combination of interferon, ribavirin and angiotensin-IItype 1 receptor blocker attenuates murine liver fibrosis development2011
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Yoshiji H, Yanase K, Fukui H
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: 28 Pages: 81-88
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Combination Treatment of Angiotensin-II Type I Receptor Blocker and New Oral Iron Chelator Attenuates Progression of Non-alcoholic Steatohepatitis in Rats.2011
- Author(s)
  Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Shirai Y, Aihara Y, Namisaki T, Yoshii J, Yanase K, Tsujimoto T, Kawaratani H, Fukui H.
- Journal Title
  
  Am J Physiol Gastrointest Liver Physiol.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Impact of Renin-Angiotensin System in Hepatocellular Carcinoma.2011
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Fukui H.
- Journal Title
  
  Curr Cancer Drug Targets.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Combination of branched-chain amino acids and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma : A randomized control trial2011
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Aihara Y, Shirai Y, Yoshiji H, Yanase K, Fukui H
- Journal Title
  
  Oncology Reports
  
  Volume: 26 Pages: 1547-1553
- Data Source
  KAKENHI-PROJECT-23590986
[Journal Article] Attenuation of insulin-resistance-based hepatocarcinogenesis and angiogenesis by combined treatment with branched-chain amino acids and angiotensin-converting enzyme inhibitor in obese diabetic rats.2010
- Author(s)
  Yoshiji H, Noguchi R, Kaji K, Ikenaka Y, Shirai Y, Namisaki T, Kitade M, Tsujimoto T, Kawaratani H, Fukui H.
- Journal Title
  
  J Gastroenterol. 45(4)
  
  Pages: 443-450
- NAID
  10027215751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] J Angiogenes Res.2010
- Author(s)
  Namisaki T, Yoshiji H, Noguchi R, Ikenaka Y, Kitade M, Kaji K, Shirai Y, Aihara Y, Yoshii J, Yanase K, Tsujimoto T, Kawaratani H, Fukui H.
- Journal Title
  
  2 16
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Selective aldosterone blocker ameliorates the progression of non-alcoholic steatohepatitis in rats.2010
- Author(s)
  Noguchi R, Yoshiji H, Ikenaka Y, Kaji K, Shirai Y, Aihara Y, Yamazaki M, Namisaki T, Kitade M, Yoshii J, Yanase K, Kawaratani H, Tsujimoto T, Fukui H.
- Journal Title
  
  Int J Mol Med. 26(3)
  
  Pages: 407-413
- NAID
  120006669562
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Selective aldosterone blocker, eplerenone, attenuates hepatocellular carcinoma growth and angiogenesis in mice.2010
- Author(s)
  Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Shirai Y, Yoshii J, Yanase K, Namisaki T, Yamazaki M, Tsujimoto T, Kawaratani H, Fukui H.
- Journal Title
  
  Hepatol Res. 40(5)
  
  Pages: 540-549
- NAID
  10026392261
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma.2009
- Author(s)
  Yoshiji H, Noguchi R, Toyohara M, Ikenaka Y, Kitade M, Kaji K, Yamazaki M, Yamao J, Mitoro A, Sawai M, Yoshida M, Fujimoto M, Tsujimoto T, Kawaratani H, Uemura M, Fukui H.
- Journal Title
  
  J Hepatol. 51(2)
  
  Pages: 315-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Crosstalk between angiogenesis, cytokeratin-18, and insulin resistance in the progression of non-alcoholic steatohepatitis.2009
- Author(s)
  Kitade M, Yoshiji H, Noguchi R, Ikenaka Y, Kaji K, Shirai Y, Yamazaki M, Uemura M, Yamao J, Fujimoto M, Mitoro A, Toyohara M, Sawai M, Yoshida M, Morioka C, Tsujimoto T, Kawaratani H, Fukui H.
- Journal Title
  
  World J Gastroenterol. 15(41)
  
  Pages: 5193-5199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Branched-chain amino acids suppress insulin-resistance-based hepatocarcinogenesis in obese diabetic rats.2009
- Author(s)
  Yoshiji H, Noguchi R, Kitade M, Kaji K, Ikenaka Y, Namisaki T, Yoshii J, Yanase K, Yamazaki M, Tsujimoto T, Akahane T, Kawaratani H, Uemura M, Fukui H.
- Journal Title
  
  J Gastroenterol. 44(5)
  
  Pages: 483-491
- NAID
  10025175098
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Losartan, an angiotensin-II type 1 receptor blocker, attenuates the liver fibrosis development of non-alcoholic steatohepatitis in the rat.2009
- Author(s)
  Yoshiji H, Noguchi R, Ikenaka Y, Namisaki T, Kitade M, Kaji K, Shirai Y, Yoshii J, Yanase K, Yamazaki M, Tsujimoto T, Kawaratani H, Akahane T, Aihara Y, Fukui H.
- Journal Title
  
  BMC Res Notes. 2
  
  Pages: 70-70
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Synergistic inhibitory effect of gemcitabine and angiotensin type-1 receptor blocker, losartan, on murine pancreatic tumor growth via anti-angiogenic activities.2009
- Author(s)
  Noguchi R, Yoshiji H, Ikenaka Y, Namisaki T, Kitade M, Kaji K, Yoshii J, Yanase K, Yamazaki M, Tsujimoto T, Kawaratani H, Fukui H.
- Journal Title
  
  Oncol Rep. 22(2)
  
  Pages: 355-360
- NAID
  120006669561
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Journal Article] Impact of insulin resistance on the progression of chronic liver diseases.2008
- Author(s)
  Kaji K, Yoshiji H, Kitade M, Ikenaka Y, Noguchi R, Yoshii J, Yanase K, Namisaki T, Yamazaki M, Moriya K, Tsujimoto T, Kawaratani H, Akahane T, Uemura M, Fukui H.
- Journal Title
  
  Int J Mol Med. (6)
  
  Pages: 801-808
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] DPP4阻害薬及びアンギオテンシンII受容体拮抗薬併用による肝病態進展抑制効2016
- Author(s)
  大倉康志、浪崎正、野口隆一、守屋圭、北出光輝、竹田幸祐、瓦谷英人、相原洋祐、西村典久、佐藤慎哉、澤田保彦、関建一郎、増谷剛、鍛冶孝佑、吉治仁志
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル
- Year and Date
  2016-04-22
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] Antifibrotic effects of combined treatment with Farnesoid X receptor agonist and angiotensin-II type1 receptor blocker on hepatic fibrogenesis in the rat model of nonalcoholic steatohepatitis2016
- Author(s)
  Tadashi Namisaki, Yasushi Okura, Shinya Sato, Ryuichi Noguchi, Kei Moriya, Mitsuteru Kitade, Kosuke Takeda, Yosuke Aihara, Norihisa Nishimura, Yasuhiko Sawada, Kenichiro Seki, Hideto Kawaratani, Kosuke Kaji, Hitoshi Yoshiji.
- Organizer
  ヨーロッパ肝臓学会
- Place of Presentation
  バルセロナ　スペイン
- Year and Date
  2016-04-13
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] ウイルス性肝炎における肝線維化診断バイオマーカーの確立2016
- Author(s)
  野口　隆一
- Organizer
  日本肝臓学会大会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2016-11-03
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] Combination treatment of dipeptidyl peptidase IV inhibitor and angiotensin-II type 1 receptor blocker attenuates progression of nonalcoholic steatohepatitis in rats2016
- Author(s)
  Shinya Sato, Tadashi Namisaki, Kosuke Kaji, Norihisa Nishimura, Yasushi Okura, Ryuichi Noguchi, Kosuke Takeda, Kei Moriya, Mitsuteru Kitade, Kenichiro Seki, Hiroaki Takaya, Hideto Kawaratani, Yasuhiko Sawada, Naotaka Shimozato, Keisuke Nakanishi, Hitoshi Yoshiji
- Organizer
  アメリカ肝臓学会
- Place of Presentation
  ボストン　US
- Year and Date
  2016-11-11
- Data Source
  KAKENHI-PROJECT-15K08077
[Presentation] 糖尿病発症ラットにおける非環式レチノイドとアンギオテンシンII受容体拮抗薬の併用による肝発癌抑制効果2015
- Author(s)
  西村典久、北出光輝、野口隆一、吉治仁志
- Organizer
  第24回日本がん転移学会学術集会総会
- Place of Presentation
  シティプラザ大阪
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] アンギオテンシンII・アルドステロンを標的とする肝癌治療：血管新生の観点から2015
- Author(s)
  野口隆一、堂原彰敏、西村典久、吉治仁志
- Organizer
  第24回日本がん転移学会学術集会総会
- Place of Presentation
  シティプラザ大阪
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] 非アルコール性脂肪性肝疾患(NAFLD)合併2型糖尿病患者に対するDPP-IV阻害薬による肝線維化抑制の試み2015
- Author(s)
  増谷剛、野口隆一、吉治仁志
- Organizer
  第2回肝臓と糖尿病・代謝研究会
- Place of Presentation
  シーモールパレス
- Year and Date
  2015-05-23
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] インスリン抵抗性条件下における DPP4阻害薬とARB併用による新規肝線維化治療の試み2014
- Author(s)
  野口隆一、吉治仁志、福井　博
- Organizer
  第50回日本肝臓学会総会
- Place of Presentation
  ホテルニューオータニ
- Year and Date
  2014-05-29
- Data Source
  KAKENHI-PROJECT-26461018
[Presentation] Beneficial effects of combined treatment with ursodoxycholic acid (UDCA) and Angiotensin-IItype1 receptor blocker(ARB) on liver fibrosis development in the rat model of nonalcoholic steatohepatitis2013
- Author(s)
  Namisaki T, Yoshiji H, Noguchi R, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
- Organizer
  Annual Meeting of the Japanese Society for the Research of Hepatic Cells
- Place of Presentation
  Osaka
- Year and Date
  2013-09-26
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Direct renin inhibitor attenuates rat hepatocarcinogenesisi via anti-angiogenic activity2013
- Author(s)
  Aihara Y, Yoshiji H, Noguchi R, Kaji K, Namisaki T, Moriya K, Kitade M, Fukui H
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington, DC.
- Year and Date
  2013-04-10
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Combined treatment of sorafenib and angiotensin-IIreceptor blocker attenuates preneoplastic lesion development of non-alcoholic steatohepatitis in rats2013
- Author(s)
  Yoshiji H, Noguchi,R, Namisaki T. Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
- Organizer
  International Society for Hepatic Sinusoidal Research
- Place of Presentation
  Osaka
- Year and Date
  2013-09-24
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Response-guided anti-angiogenic therapy for hepatocellular carcinoma recurrence with clinically available safety agent2013
- Author(s)
  Yoshiji H, Noguchi R, Kaji K, Aihara Y, Namisaki T, Moriya K, Douhara A, Kitade M, Fukui H
- Organizer
  AACR Annual Meeting 2013
- Place of Presentation
  Washington, DC.
- Year and Date
  2013-04-10
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Inhibition of endotoxin cascade with antibiotics attenuates the liver fibrosis development in rat model of nonalcoholic steatohepatitis2013
- Author(s)
  Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kitade M, Aihara Y, Kawaratani H, Nishimura N, Fukui H
- Organizer
  International Society for Hepatic Sinusoidal Research
- Place of Presentation
  Osaka
- Year and Date
  2013-09-24
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Combination of angiotensin-converting enzyme inhibitor and selective aldosterone blocker, suppresses the liver fibrosis carcinogenesis of nonalcoholic steatohepatitis in the rat2013
- Author(s)
  Noguchi R, Yoshiji H, Namisaki T, Moriya K, Kitade M, Aihara Y, Douhara A, Kawaratani H, Nishimura N, Fukui H
- Organizer
  International Society for Hepatic Sinusoidal Research
- Place of Presentation
  Osaka
- Year and Date
  2013-09-24
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Effect of sorafenib on HCV-related hepatocellular carcinoma (HCC)2012
- Author(s)
  Douhara A, Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kaji K, Aihara Y, Yamao J, Mitoro A, Fukui H
- Organizer
  JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Crosstalk between glucose intolerance and liver fibrosis development in patients with chronic hepatitis C2012
- Author(s)
  Aihara Y, Yoshiji H, Noguchi R, Namisaki T, Moriya K, Kaji K, Douhara A, Fukui H
- Organizer
  JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Douhara A, Aihara Y, Yamao J, Mitoro A, Fukui H. Efficacy of combination therapy with peg-interferon alpha and ribavirin in elderly chronic hepatitis C2012
- Author(s)
  Moriya K, Yoshiji H, Noguchi R, Namisaki T, Kaji K
- Organizer
  JSH Single Topic Conference
- Place of Presentation
  Tokyo
- Year and Date
  2012-11-21
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Inhibitory effect of selective aldosterone blocker on hepatocellular carcinoma development via angiogenesis suppression2011
- Author(s)
  Kaji K, Yoshiji H, Ikenaka Y, Noguchi R, Fukui H
- Organizer
  ILCA
- Place of Presentation
  Hong-Kong
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Combination of branched-chain amino acid and angiotensin-converting enzyme inhibitor suppresses the cumulative recurrence of hepatocellular carcinoma under the condition of insulin resistance2011
- Author(s)
  Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Aihara Y, Fukui H
- Organizer
  ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
- Place of Presentation
  Osaka
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Combination of branched-amino acids and angiotensin-converting enzyme inhibitor attenuates the insulin resintance-based hepatocarcinogenesis via angiogenesis suppression2011
- Author(s)
  Aihara Y, Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Fukui H
- Organizer
  ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
- Place of Presentation
  Osaka
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Combination of branched-amino acids and angiotensin-converting enzyme inhibitor attenuates the insulin resistance -based hepatocarcinogenesis via angiogenesis suppression2011
- Author(s)
  Aihara Y, Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Fukui H
- Organizer
  ILCA
- Place of Presentation
  Hong-Kong
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Clinically available selective aldosterone blocker attenuates hepatocarcinogenesis via angiogenesis inhibition in rats2011
- Author(s)
  Noguchi R, Yoshiji H, Ikenaka Y, Aihara Y, Fukui H
- Organizer
  ILCA
- Place of Presentation
  Hong-Kong
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Soluble VEGF receptor-2 may be a predictive marker of anti-angiogenic chemopreventive therapy with clinically available safe agents2011
- Author(s)
  Yoshiji H, Ikenaka Y, Noguchi R, Kaji K, Aihara Y, Fukui H
- Organizer
  ILCA
- Place of Presentation
  Hong-Kong
- Year and Date
  2011-09-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Clinically available selective aldosterone blocker attenuates hepatocarcinogenesis via angiogenesis inhibition in rats2011
- Author(s)
  Noguchi R, Yoshiji H, Ikenaka Y, Kaji K, Shirai Y, Fukui H
- Organizer
  ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
- Place of Presentation
  Osaka
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Inhibitory effect of selective aldosterone blocker on hepatocellular carcinoma development via angiogenesis suppression2011
- Author(s)
  Kaji K, Yoshiji H, Ikenaka Y, Noguchi R, Aihara Y, Fukui H
- Organizer
  ASIA-PACIFIC PRIMARY LIVER CANCER EXPERT MEETING
- Place of Presentation
  Osaka
- Year and Date
  2011-07-03
- Data Source
  KAKENHI-PROJECT-23590986
[Presentation] Clinically used selective aldosterone blocker attenuates hepatocarcinogenesis via angiogenesis inhibition in rats.2010
- Author(s)
  野口隆一, 吉治仁志, 池中康英, 鍛治孝祐, 白井勇作, 福井博
- Organizer
  AACR.
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] An alternative VEGF-targeted therapy and possible prediction against hepatocellular carcinoma(HCC) using combination of clinically available agents.2010
- Author(s)
  吉治仁志, 池中康英, 野口隆一, 鍛治孝祐, 白井勇作, 福井博
- Organizer
  AACR.
- Year and Date
  2010-04-20
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 選択的アルドステロン阻害薬による抗血管新生に基づく肝発癌抑制効果2010
- Author(s)
  野口隆一、吉治仁志、池中康英、鍛治孝祐、白井勇作、相原洋祐、福井博
- Organizer
  日本癌学会学術総会
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] Renin-angiotensin system in hepatic fibrogenesis.2010
- Author(s)
  吉治仁志, 池中康英, 野口隆一, 鍛治孝祐, 白井勇作, 相原洋祐, 福井博
- Organizer
  JSH Single Topic Conference.
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] インスリン抵抗性条件下肝癌再発に対する安全な既存薬剤を用いたVEGFを分子標的とした新規治療法2010
- Author(s)
  吉治仁志、野口隆一、北出光輝、鍛治孝祐、池中康英、白井勇作、相原洋祐、福井博
- Organizer
  日本癌学会学術総会
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] アンジオテンシンIIとアルドステロンdual blockによるNASH肝線維化進展抑制の試み2010
- Author(s)
  野口隆一、吉治仁志、福井博
- Organizer
  日本消化器病学会大会
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] NASH進展過程におけるアルドステロンの役割と選択的アルドステロン阻害薬による治療の試み2010
- Author(s)
  野口隆一、吉治仁志、福井博
- Organizer
  日本肝臓学会総会
- Year and Date
  2010-05-28
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 肝炎ウイルスによる肝癌に対する分子標的治療2010
- Author(s)
  吉治仁志、野口隆一、福井博
- Organizer
  日本感染症学会総会
- Year and Date
  2010-04-05
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] Amelioration of the Non-alcoholic steatohepatitis by clinically available selective aldosterone blocker in rats.2010
- Author(s)
  野口隆一, 吉治仁志, 鍛治孝祐, 相原洋祐, 福井博
- Organizer
  JSH Single Topic Conference.
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 血管新生阻害に基づくBCAAとACE阻害薬併用によるインシュリン抵抗性条件下肝発癌抑制効果2009
- Author(s)
  吉治仁志、野口隆一、北出光輝、加治幸祐、池中康英、白井勇作、浪崎正、山崎正晴、福井博
- Organizer
  日本癌学会学術総会
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 選択的アルドステロンブロッカーによる肝線維化抑制効果の検討2009
- Author(s)
  野口隆一、吉治仁志、池中康英、北出光輝、鍛治孝祐、浪崎正、吉井純一、簗瀬公嗣、福井博
- Organizer
  日本消化器病学会総会
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 肝線維化進展におけるアルドステロンの役割と作用機序2009
- Author(s)
  野口隆一、吉治仁志、福井博
- Organizer
  日本肝臓学会大会
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 選択的アルドステロン阻害剤による血管新生阻害と肝癌発育抑制2009
- Author(s)
  野口隆一、吉治仁志、北出光輝、鍛治孝祐、池中康英、白井勇作、浪崎正、山崎正晴、福井博
- Organizer
  日本癌学会学術総会
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] Suppressive effect on the cumulative recurrence of hepatocellular carcinoma with combination treatment of clinically available vitamin K2 and angiotensin-converting enzyme inhibitor.2009
- Author(s)
  野口隆一, 吉治仁志, 池中康英, 北出光輝, 鍛治孝祐, 浪崎正, 相原洋祐, 福井博
- Organizer
  APASL
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] ACE阻害剤、ビタミンK杯用による肝癌の分子標的治療:VEGFの変動からみた肝癌再発抑制効果の予測2009
- Author(s)
  吉治仁志、野口隆一、福井博
- Organizer
  日本肝臓学会大会
- Year and Date
  2009-10-15
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] インスリン抵抗性条件下の肝癌発生における血管新生の関与:分枝鎖アミノ酸(BCAA)とACE阻害薬併用による予防の試み2009
- Author(s)
  吉治仁志、池中康英、野口隆一、北出光輝、鍛治孝祐、白井勇作、浪崎正、吉井純一、簗瀬公嗣、山崎正晴、福井博
- Organizer
  日本肝臓学会総会
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] VEGF-targeted therapy against insulin -resistance-based rat hepatocarcinogenesis with clinically available agent : branched-chain amino acid (BCAA) granules.2009
- Author(s)
  吉治仁志, 野口隆一, 北出光輝, 鍛治孝祐, 池中康英, 浪崎正, 相原洋祐, 福井博
- Organizer
  APASL
- Year and Date
  2009-02-14
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 血管新生とインスリン抵抗性の肝線維化進展における役割:慢性C型肝炎患者における検討2009
- Author(s)
  野口隆一、吉治仁志、池中康英、浪崎正、北出光輝、鍛治孝祐、白井勇作、福井博
- Organizer
  日本肝臓学会西部会
- Year and Date
  2009-12-05
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 非アルコール性脂肪性肝炎における自然免疫:クッパー細胞機能と新しい診断と治療への応用2009
- Author(s)
  野口隆一、吉治仁志、池中康英、鍛治孝祐、浪崎正、吉井純一、簗瀬公嗣、福井博
- Organizer
  日本肝臓学会総会
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] 膵癌発育におけるGemcitabineとLosartan併用による相乗的抗腫瘍効果:血管新生の関与2008
- Author(s)
  野口隆一、吉治仁志、池中康英、北出光輝、鍛治孝祐、浪崎正、吉井純一、簗瀬公嗣、山崎正晴、福井博
- Organizer
  日本癌学会学術総会
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] インスリン抵抗性条件下におけるVEGFを標的としたBCAA製剤による肝発癌抑制効果2008
- Author(s)
  吉治仁志、北出光輝、鍛治孝祐、池中康英、野口隆一、浪崎正、吉井純一、簗瀬公嗣、山崎正晴、福井博
- Organizer
  日本癌学会学術総会
- Year and Date
  2008-10-29
- Data Source
  KAKENHI-PROJECT-20590792
[Presentation] Gemcitabin無効例に対するARB併用による膵癌発育抑制効果とその機序:血管新生因子VEGFの関与2008
- Author(s)
  野口隆一、吉治仁志、鍛治孝祐、北出光輝、池中康英、山崎正晴、福井博
- Organizer
  日本消化器病学会大会
- Year and Date
  2008-10-03
- Data Source
  KAKENHI-PROJECT-20590792

1. YOSHIJI Hitoshi (40336855)

# of Collaborated Projects: 5 results

# of Collaborated Products: 86 results
2. NAMISAKI TADASHI (20526850)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. MORIYA KEI (40526852)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. KITADE MITSUTERU (40526795)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. NISHIMURA NORIHISA

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
6. MATSUMOTO MASANORI (60316081)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. MASHITANI TSUYOSHI (20401929)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
8. 鍛治孝祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Noguchi Ryuichi 野口 隆一

NOGUCHI Ryuuichi 野口 隆一

Research Projects

Research Products

Co-Researchers

Therapeutic effect of Equol on gut microbiome - mediated NASH progressionPrincipal Investigator

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Identification of novel treatment and biomarkers based on pharmacokinetics in patients with hepatocellular carcinoma

Principal Investigator

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Establishment of new treatment targeting lifestyle diseases and coagulation fibrinolytic system related to the development of NASHPrincipal Investigator

Principal Investigator

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Research Institution

Establishment of new therapy for chronic liver diseases progression

Principal Investigator

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Crosstalk of renin-angiotensin system in the chronic liver diseases and therapeutic applications

Principal Investigator

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[Book] The Liver Cancer Journal2016

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[Book] Annual Review 2016 消化器2016

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[Book] 消化器病学の進歩-原点から未来への情報発信-(血管新生因子VEGFを標的とした肝癌再発抑制:ACE阻害剤、ビタミンK併用療法の臨床的検討)2009

Author(s)

Total Pages

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Data Source

[Book] 消化器疾患におけるエピゲノミクスとゲノミクス(血管新生因子VEGFに対する既存薬剤を用いた分子標的治療の試み:インスリン抵抗性条件下での肝発癌に対するBCAAの効果)2009

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[Book] 肝胆膵(レニン・アンジオテンシン系阻害薬)2009

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[Book] 慢性肝疾患 日本臨床2009

Author(s)

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[Book] 肝胆膵(血管新生阻害剤の新しい展開「肝癌」)2009

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[Journal Article] Effect of combined farnesoid X receptor agonist and angiotensin Ⅱtipe 1 receptor blocker on hepatic fibrosis.2017

Author(s)

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[Journal Article] Combined treatment with dipeptidyl peptidase-4 inhibitor (sitagliptin) and angiotensin-II type 1 receptor blocker (losartan) suppresses progression in a non-diabetic rat model of steatohepatitis.2016

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Journal Title

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Data Source

[Journal Article] DNA methylation of angiotensin II receptor gene in nonalcoholic steatohepatitis-related liver fibrosis.2016

Noguchi Ryuichi 野口隆一

NOGUCHI Ryuuichi 野口隆一

[Book] 慢性肝疾患日本臨床2009