SHINOZUKA Keiji 篠塚啓二

… Alternative Names

篠塚啓二シノヅカケイジ

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Researcher Number	30431745
Other IDs
Affiliation (Current)	2025: 日本大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 日本大学, 歯学部, 講師 2016 – 2021: 日本大学, 歯学部, 助教 2015: 帝京大学, 医学部, 助手 2012: 筑波大学, 医学医療系, 助教
Review Section/Research Field	Principal Investigator Surgical dentistry / Basic Section 57060:Surgical dentistry-related Except Principal Investigator Basic Section 57040:Regenerative dentistry and dental engineering-related / Basic Section 57020:Oral pathobiological science-related / Basic Section 57060:Surgical dentistry-related
Keywords	Principal Investigator 口腔癌 / ネットワーク解析 / microRNA / 癌関連遺伝子 / 口腔がん / マイクロアレイ解析 / エクソソーム / microRNAアレイ解析 / 遺伝子 / バイオマーカー … More / 遺伝子ネットワーク / マイクロRNA / スーパーエンハンサー / 遺伝子ネットワーク解析 / パスウェイ解析 / バイオインフォマティクス / がん関連遺伝子 / microRNA アレイ解析 … More Except Principal Investigator 軟組織細胞 / アルカリフォスファターゼ / ポリリン酸 / 硬組織 / 三次元培養体 / 自己免疫疾患 / 炎症 / 歯肉 / 活性酸素種 / オートファジー / 歯肉培養系モデル / 歯肉オルガノイド / 白血球 / 血管 / HDAC阻害 / 三次元培養系 / DAMPs / 歯肉上皮細胞 / 歯周組織 / オルガノイド / マクロファージ / 細胞死 / 歯肉上皮 / 短鎖脂肪酸 / 顎変形症 / 気道流体解析 / 閉塞性睡眠時無呼吸障害 / 気道変化 / 数値流体力学シミュレーション / 上下顎前方移動術 / 閉塞性睡眠時無呼吸症 / 数値流体力学 Less

Development of a three-dimensional hard tissue culture system using inorganic polyphosphate and soft-tissue cells.
- Principal Investigator
  
  津田啓方
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57040:Regenerative dentistry and dental engineering-related
- Research Institution
  Nihon University
スーパーエンハンサーを標的とする遺伝子発現制御による口腔癌発癌機構の解明Principal Investigator
- Principal Investigator
  
  篠塚啓二
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Development of human gingival organoid systems and investigation for the induction mechanisms of gingival inflammation and autoimmune diseases.
- Principal Investigator
  
  TSUDA Hiromasa
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Nihon University
Development of highly sensitive diagnostic and therapeutic methods using exosomes as a new biomarker for oral cancerPrincipal Investigator
- Principal Investigator
  
  SHINOZUKA Keiji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
A study of efficient jaw movement in obstructive sleep apena
- Principal Investigator
  
  TONOGI Morio
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Development of novel diagnosis and therapy based on exosome for oral carcinomaPrincipal Investigator
- Principal Investigator
  
  SHINOZUKA Keiji
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
Identification of network related tumor suppressor miRNA in oral cancerPrincipal Investigator
- Principal Investigator
  
  SHINOZUKA Keiji
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Surgical dentistry
- Research Institution
  Nihon University
  Teikyo University
ＭｉｃｒｏＲＮＡと標的遺伝子による口腔癌の網羅的ネットワークの解明と治療法の開発Principal Investigator
- Principal Investigator
  
  篠塚啓二
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Surgical dentistry
- Research Institution
  University of Tsukuba

All 2024 2023 2022 2021 2020 2019 2017 2016 2013 Other

All Journal Article Presentation Other

[Journal Article] Reactive oxygen species generation required for autophagy induction during butyrate- or propionate-induced release of damage-associated molecular patterns from dying gingival epithelial Ca9-22 cells2024
- Author(s)
  Miyake Kiwa、Mikami Yoshikazu、Asayama Takayuki、Toriumi Taku、Shinozuka Keiji、Tonogi Morio、Yonehara Yoshiyuki、Tsuda Hiromasa
- Journal Title
  
  Journal of Oral Science
  
  Volume: 66 Issue: 2 Pages: 125-129
- DOI
  10.2334/josnusd.23-0421
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09913
[Journal Article] Butyrate-treatment induces gingival epithelial cell death in a three-dimensional gingival-connective tissue hybrid co-culture system2023
- Author(s)
  Kurosawa Yusuke、Yamaguchi Hirofumi、Uemichi Kazuki、Shinozuka Keiji、Kirihara Yuki、Tsuda Hiromasa
- Journal Title
  
  Journal of Dental Sciences
  
  Volume: 18 Issue: 2 Pages: 893-897
- DOI
  10.1016/j.jds.2022.08.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09913
[Journal Article] Histone-deacetylase-inhibitory effects of periodontopathic-bacterial metabolites induce human gingival epithelial Ca9-22 cell death2022
- Author(s)
  Uemichi Kazuki、Mikami Yoshikazu、Watanabe Takayasu、Shinozuka Keiji、Tonogi Morio、Tsuda Hiromasa
- Journal Title
  
  Odontology
  
  Volume: - Issue: 3 Pages: 658-667
- DOI
  10.1007/s10266-022-00775-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09913
[Journal Article] Bioinformatics analysis of dysregulated exosomal microRNAs derived from oral squamous cell carcinoma cells2021
- Author(s)
  Masaoka Tadashi、Shinozuka Keiji、Ohara Kenshin、Tsuda Hiromasa、Imai Kenichi、Tonogi Morio
- Journal Title
  
  Journal of Oral Science
  
  Volume: 63 Issue: 2 Pages: 174-178
- DOI
  10.2334/josnusd.20-0662
- NAID
  130008009559
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09913, KAKENHI-PROJECT-20K10126
[Journal Article] Rapid detection of Candida albicans in oral exfoliative cytology samples by loop-mediated isothermal amplification.2017
- Author(s)
  Noguchi H, Iwase T, Omagari D, Asano M, Nakamura R, Ueki K, Shinozuka K, Kaneko T, Tonogi M, Ohki H
- Journal Title
  
  J Oral Sci
  
  Volume: 印刷中
- NAID
  130006286530
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06626
[Journal Article] Hemiatrophy of the tongue and hypoglossal nerve palsy presenting with hypoglossal schwannoma: A rare case report.2017
- Author(s)
  Shinozuka K, Ichinokawa Y, Hanaue N, Ohara K, Shimizu O, Kaneko T, Tonogi M, Ohki H
- Journal Title
  
  J Oral Maxillofac Surg Med Pathol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06626
[Journal Article] Impact of polymorphic variations of gemcitabine metabolism, DNA damage repair, and drug resistance genes on the effect of high-dose chemotherapy for relapsed or refractory lymphoid malignancies.2016
- Author(s)
  Shinozuka K, Tang H, Jones RB, Li D, Nieto Y
- Journal Title
  
  Biol Blood Marrow Transplan
  
  Volume: 22 Pages: 843-849
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06626
[Journal Article] MicroRNA-125b regulates proliferation and radioresistance of oral squamous cell carcinoma.2013
- Author(s)
  椎葉正史、篠塚啓二
- Journal Title
  
  British Journal of Cancer
  
  Volume: 未定 Issue: 9 Pages: 1817-1821
- DOI
  10.1038/bjc.2013.175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24792173
[Presentation] バイオインフォマティクス解析によるがんバイオマーカーの探索～口腔癌におけるエクソソーム由来マイクロRNAを起点とした機能性ネットワークの解析．2022
- Author(s)
  篠塚啓二
- Organizer
  QIAGEN Ingenuity Pathway Analysis User Group Meeting
- Invited
- Data Source
  KAKENHI-PROJECT-20K10126
[Presentation] 歯肉上皮細胞の短鎖脂肪酸誘導細胞死には活性酸素によるオートファジー誘導が必要である2022
- Author(s)
  三宅希和，津田啓方，篠塚啓二，鈴木直人，外木守雄
- Organizer
  第74回日本大学歯学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-20K09913
[Presentation] Bioinformatics analysis of dysregulated exosomal microRNAs derived from cancer cells.2022
- Author(s)
  Keiji Shinozuka
- Organizer
  Scientific Program: Vebleo Webinar on Genetics and Molecular Biology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10126
[Presentation] 数値流体力学の鼻咽腔気流解析への応用2021
- Author(s)
  田沼唯士，山縣加夏子，篠塚啓二，荻澤翔平，外木守雄
- Organizer
  日本睡眠学会第46回定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 数値流体力学解析による上下顎前方移動術が上気道故宮導体に与える影響について．2021
- Author(s)
  山縣加夏子，篠塚啓二，青木淳也，荻澤翔平，西久保周一，佐藤貴子，鈴木雅明，田沼唯士，外木守雄
- Organizer
  日本睡眠学会第46回定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 数値流体シミュレーションを用いた上下顎前方移動および舌骨上筋群牽引術前後における上気道呼吸動態の変化について．2021
- Author(s)
  山縣加夏子, 篠塚啓二, 草野明美, 荻澤翔平, 阿崎宏昭, 西久保周一，佐藤貴子，山田剛也, 田沼唯士, 外木守雄
- Organizer
  第75回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 流体力学的手法を用いた上気道の呼吸動態の評価2021
- Author(s)
  山縣加夏子，篠塚啓二，荻澤翔平，田沼唯士，外木守雄
- Organizer
  日本睡眠学会第46回定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 睡眠時無呼吸症患者における数値流体解析を用いたシミュレーションによる手術前後の気道変化について2020
- Author(s)
  山縣加夏子, 篠塚啓二, 草野明美, 荻澤翔平, 佐藤貴子, 西久保周一, 山田剛也, 大木秀郎, 田沼唯士, 外木守雄
- Organizer
  第74回日本口腔科学会学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 閉塞性睡眠時無呼吸に対する上下顎前方移動術後の口腔容積に占める舌の比較検討2020
- Author(s)
  荻澤翔平, 西久保周一, 阿崎宏昭, 山縣加夏子, 植木皓介, 草野明美, 篠塚啓二, 佐藤貴子, 外木守雄
- Organizer
  第19回日本睡眠歯科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 顎矯正手術による顎骨移動と顎顔面形態が上気道抵抗に及ぼす影響について2020
- Author(s)
  阿崎宏昭, 篠塚啓二, 山縣加夏子, 草野明美, 荻澤翔平, 青木淳也, 座間学, 大谷紗織, 山田剛也, 西久保周一, 佐藤貴子, 磯野史朗, 外木守雄
- Organizer
  第19回日本睡眠歯科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 手術による顎骨移動が上気道抵抗に及ぼす生理学的な検討2019
- Author(s)
  阿崎宏昭, 篠塚啓二, 山縣加夏子, 草野明美, 中村亮太, 青木淳也, 西久保周一, 佐藤貴子, 磯野史朗, 外木守雄
- Organizer
  第18回日本睡眠歯科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 顎矯正手術の術前後における気道形態の変化について2019
- Author(s)
  青木淳也, 篠塚啓二, 山縣加夏子, 中村亮太, 草野明美, 阿崎宏昭, 西久保周一, 佐藤貴子, 清水治, 外木守雄
- Organizer
  第29回日本顎変形症学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] OSA数値流体力学解析up-todate　上下顎前方移動術における気道動態の変化(第1報)　流体力学を用いたシミュレーション2019
- Author(s)
  山縣加夏子, 篠塚啓二, 荻澤翔平, 田沼唯士, 外木守雄
- Organizer
  第44回日本睡眠学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 顎骨の移動が上気道の生理学的抵抗の変化に及ぼす影響について2019
- Author(s)
  阿崎宏昭, 篠塚啓二, 山縣加夏子, 草野明美, 中村亮太, 青木淳也, 柳川圭一, 西久保周一, 佐藤貴子, 清水治, 磯野史朗, 外木守雄
- Organizer
  第44回日本睡眠学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 上下顎前方移動術・オトガイ舌筋舌骨筋前方移動術が上気道形態および睡眠におよぼす影響2019
- Author(s)
  中村亮太, 佐藤貴子, 姫嶋皓大, 荻澤翔平, 篠塚啓二, 山田剛也, 外木守雄
- Organizer
  第29回日本顎変形症学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 流体解析を用いたシミュレーションによる顎変形症患者の手術前後の気道動態の変化2019
- Author(s)
  山縣加夏子, 篠塚啓二, 外木守雄
- Organizer
  第７１回日本大学歯学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] OSA数値流体力学解析up-todate　上下顎前方移動術における気道動態の変化(第2報)　CFDによる術前効果予測の検討2019
- Author(s)
  荻澤翔平, 篠塚啓二, 山縣加夏子, 田沼唯士, 外木守雄
- Organizer
  第44回日本睡眠学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 流体解析を用いたシミュレーションによる睡眠時無呼吸症患者の手術前後の気道変化について2019
- Author(s)
  山縣加夏子, 篠塚啓二, 荻澤翔平, 中村亮太, 西久保周一, 佐藤貴子, 鈴木雅明, 田沼唯士, 外木守雄
- Organizer
  第44回日本睡眠学会定期学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[Presentation] 顎矯正手術の上顎移動量・移動方向が上気道形態におよぼす影響について2019
- Author(s)
  青木淳也, 篠塚啓二, 山縣加夏子, 柳川圭一, 中村亮太, 佐藤貴子, 姫嶋皓大, 西久保周一, 山田剛也, 外木守雄
- Organizer
  第18回日本睡眠歯科学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-19K10294
[]

1. TSUDA Hiromasa (60325470)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
2. TONOGI Morio (50217519)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. 三上剛和 (80434075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 鳥海拓 (40610308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 佐藤貴子 (40398863)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. 西久保周一 (40408357)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. 市ノ川義美 (20203101)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 花上伸明 (40385232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小原研心 (70598507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 白土博司 (50710844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 平田亮介 (00808735)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 兼古晃輔 (40459342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 関谷秀樹 (70267540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHINOZUKA Keiji 篠塚 啓二

篠塚 啓二 シノヅカ ケイジ

Research Projects

Research Products

Co-Researchers

Development of a three-dimensional hard tissue culture system using inorganic polyphosphate and soft-tissue cells.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

スーパーエンハンサーを標的とする遺伝子発現制御による口腔癌発癌機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of human gingival organoid systems and investigation for the induction mechanisms of gingival inflammation and autoimmune diseases.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of highly sensitive diagnostic and therapeutic methods using exosomes as a new biomarker for oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study of efficient jaw movement in obstructive sleep apena

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel diagnosis and therapy based on exosome for oral carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of network related tumor suppressor miRNA in oral cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ＭｉｃｒｏＲＮＡと標的遺伝子による口腔癌の網羅的ネットワークの解明と治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Reactive oxygen species generation required for autophagy induction during butyrate- or propionate-induced release of damage-associated molecular patterns from dying gingival epithelial Ca9-22 cells2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Butyrate-treatment induces gingival epithelial cell death in a three-dimensional gingival-connective tissue hybrid co-culture system2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Histone-deacetylase-inhibitory effects of periodontopathic-bacterial metabolites induce human gingival epithelial Ca9-22 cell death2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bioinformatics analysis of dysregulated exosomal microRNAs derived from oral squamous cell carcinoma cells2021

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Rapid detection of Candida albicans in oral exfoliative cytology samples by loop-mediated isothermal amplification.2017

Author(s)

SHINOZUKA Keiji 篠塚啓二

篠塚啓二シノヅカケイジ

[Presentation] OSA数値流体力学解析up-todate　上下顎前方移動術における気道動態の変化(第1報)　流体力学を用いたシミュレーション2019