Nagai Yoshinori 長井良憲

… Alternative Names

NAGAI Yoshinori 長井良憲

Less

Researcher Number	30431761
Other IDs
Affiliation (Current)	2025: 富山県立大学, 工学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 富山県立大学, 工学部, 教授 2018 – 2019: 富山県立大学, 工学部, 教授 2017: 富山大学, 大学院医学薬学研究部(医学), 准教授 2016 – 2017: 富山大学, 大学院医学薬学研究部(医学), 客員教授 2012 – 2015: 富山大学, 大学院医学薬学研究部(医学), 客員准教授 … More 2014: 富山大学, 大学院医学薬学研究部(医学), 准教授 2012: 富山大学, 大学院・医学薬学研究部, 客員准教授 2011 – 2012: 富山大学, 大学院医学薬学研究部(医学), 准教授 2009 – 2011: 富山大学, 大学院・医学薬学研究部(医学), 准教授 2006 – 2010: 富山大学, 大学院・医学薬学研究部, 准教授 2009: 富山大学, 医学薬学研究部, 准教授 2008: University of Toyama, 大学院医学薬学研究部, 准教授 Less
Review Section/Research Field	Principal Investigator Immunology / Biological Sciences / Basic Section 49030:Experimental pathology-related / Basic Section 47040:Pharmacology-related Except Principal Investigator Immunology / Biological pharmacy / Metabolomics / Drug development chemistry / Pediatrics / Applied pharmacology / Biological Sciences
Keywords	Principal Investigator 自然免疫 / 免疫学 / 肥満 / 脂質 / Toll-like receptor / 腸内細菌叢 / 線維化 / 腸内細菌 / マクロファージ / 非アルコール性脂肪性肝炎 … More / 低分子化合物 / 全身性エリテマトーデス / レプチン抵抗性 / 摂食異常 / 視床下部炎症 / レプチン / 摂食調節 / TLR / 天然薬物 / 糖尿病 / 自己免疫病 / 造血分化 … More Except Principal Investigator 自然免疫 / IL-5 / 免疫学 / NLRP3 / 腫瘍 / ベツリン / 糖尿病 / 炎症 / TLR / 癌 / IFN-γ / 結核菌 / リンパ球 / 脂肪酸 / 脂肪組織 / 内臓脂肪組織 / IL-1 beta / 脂肪細胞 / 好中球 / PD-L1 / インフラマソーム / 慢性炎症 / NLRP3インフラマソーム / イソリクイリチゲニン / IL-1β / 先天代謝異常 / ABCD1 / 極長鎖脂肪酸 / ミクログリア / ABCタンパク質 / 骨髄移植 / ペルオキシソーム / 神経変性疾患 / 副腎白質ジストロフィー / 好酸球 / 免疫監視・腫瘍免疫 / 粘膜免疫 / サイトカイン / 肥満 / 天然物 / 非感染性慢性炎症 / 免疫関連疾患 / アレルギー / 再生医療 / 骨髄由来多能性前駆細胞 / 組織再生 / 薬物治療学 / Iigp1 / 抗原交叉提示 / トランスジェニックマウス / I-A拘束性 / Th1抗原ペプチド / 細胞障害活性 / CD40-CD40L / アジュバント効果 / IFN--γ / アジュバント活性 / 抗腫瘍免疫増強 / クロスプレゼンテーション / 抗原提示細胞 / Th2 / Th1 / Peptide-25 / Ag85B / APS / Lnk / クラススイッチ組換え / IgA / Bリンパ球 / 造血幹細胞 / クラススイッチ / B-1細胞 / インターロイキン5 / クラススイッチ変換 / アダプター分子 / インターロイキン Less

肝臓マクロファージサブセット解析から迫る新規線維化亢進NASHマウスの病態解明Principal Investigator
- Principal Investigator
  
  長井良憲
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Toyama Prefectural University
Development of novel autoimmune therapeutics that selectively inhibit TLR7 activationPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshinori
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Toyama Prefectural University
Adrenoleukodystrophy: effect of bone marrow transplantation in abcd1-deficient mouse
- Principal Investigator
  
  MORITA MASASHI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  University of Toyama
Free fatty acids-mediated dynamic changes of neutrophils induce adipose tissue inflammation
- Principal Investigator
  
  Watanabe Yasuharu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  University of Toyama
Elucidation of the mechanism of the innate immune signal that induces hypothalamic inflammation and feeding dysfunctionPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshinori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  University of Toyama
Search for the target molecule of the licorice component inhibiting NLRP3 inflammasome and development into drug discovery research
- Principal Investigator
  
  HONDA Hiroe
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toyama Prefectural Institute. for Pharmaceutical Research.
Study on the drug development for tumor immunotherapy based on immune-restoring activity of a plant ingredient betulin.
- Principal Investigator
  
  Ogasaawara Masaru
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Drug development chemistry
- Research Institution
  Toyama Prefectural Institute. for Pharmaceutical Research.
自然免疫シグナル分子による摂食反応・肥満制御機構の解明Principal Investigator
- Principal Investigator
  
  長井良憲
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
脂肪組織炎症を制御するＲＰ１０５／ＭＤ－１の機能解析及び内因性リガンドの探索Principal Investigator
- Principal Investigator
  
  長井良憲
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
Analysis of innate IL-5 producing cells in immune responses and chronic inflammation
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  University of Toyama
A mechanism of action of a plant ingredient betulin on restoring the suppression of antitumor activity of immune cells by TGF-beta or PGE2.
- Principal Investigator
  
  OGASAWARA MASARU
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Toyama Prefectural Institute. for Pharmaceutical Research.
Search for innate immune molecules and compounds that regulate adipose tissue inflammationPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshinori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  University of Toyama
Spatiotemporal control of allergy and non-infectious inflammation and their regulation by natural products
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Immunology
- Research Institution
  Toyama Prefectural Institute. for Pharmaceutical Research.
脂肪組織の自然炎症におけるRP105/MD-1シグナルと可溶型MD-1の機能解析Principal Investigator
- Principal Investigator
  
  長井良憲
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
Elucidation of the source of pluripotent progenitor cells in systemic inflammatory mouse model
- Principal Investigator
  
  YAMAMOTO Seiji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Toyama
Roles of lipid-recognition molecules in autoimmune diseasesPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshinori
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  University of Toyama
Roles of cytokines and TLRs in lymphocyte activation and differentiation
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Immunology
- Research Institution
  University of Toyama
Differentiation and maturation of innate immune cells via TLRPrincipal Investigator
- Principal Investigator
  
  NAGAI Yoshinori
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  University of Toyama
Enhancement of Th1 and antitumor immunity by Ag85B and Peptide-25.
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  University of Toyama
  The University of Tokyo
Investigation of regulatory mechanisms for homeostasis and activation of lymphocyte
- Principal Investigator
  
  TAKATSU Kiyoshi
- Project Period (FY)
  2004 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Immunology
- Research Institution
  The University of Tokyo
  University of Toyama

[Book] Biological activities and action mechanisms of licorice ingredients2017
- Author(s)
  Nagai Y, Watanabe Y, Honda H, Takatsu K
- Total Pages
  172
- Publisher
  InTech
- ISBN
  9789535131205
- Data Source
  KAKENHI-PROJECT-16K19532
[Book] Chapter 8 Isoliquiritigenin: A unique licorice component that attenuates adipose tissue inflammation and fibrosis by targeting the innate immune sensors. In “Biological activities and action mechanisms of licorice ingredients” (ed. H. Sakagami)2017
- Author(s)
  Nagai Y, Watanabe Y, Honda H, Takatsu K
- Total Pages
  14
- Publisher
  InTech
- Data Source
  KAKENHI-PROJECT-15K07960
[Book] Chronic Inflammation: Mechanisms and Regulation2016
- Author(s)
  Nagai Y, Honda H, Watanabe Y, Takatsu K
- Total Pages
  702
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-16K19532
[Book] Chapter 30 Potential therapeutic natural products for the treatment of obesity-associated inflammation by targeting TLRs and inflammasomes. In “Chronic Inflammation-Mechanisms and Regulation-” (M. Miyasaka and K. Takatsu), pp. 379-3972016
- Author(s)
  Nagai Y, Honda H, Watanabe Y, Takatsu K.
- Total Pages
  19
- Publisher
  Springer Japan
- Data Source
  KAKENHI-PROJECT-15K07960
[Book] 第4章 13節 RP105. 「seriesモデル動物利用マニュアル　疾患モデルの作製と利用ー脂質代謝異常と関連疾患<下巻>」. 尾池雄一, 佐々木雄彦, 村上誠, 矢作直也編集.2015
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Total Pages
  10
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-24390119
[Book] 第4章 13節 RP105. 「seriesモデル動物利用マニュアル　疾患モデルの作製と利用ー脂質代謝異常と関連疾患<下巻>」. 尾池雄一, 佐々木雄彦, 村上誠, 矢作直也編集.2015
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Total Pages
  10
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PUBLICLY-25126707
[Book] 第4章 13節 RP105. 「seriesモデル動物利用マニュアル　疾患モデルの作製と利用ー脂質代謝異常と関連疾患<下巻>」. 尾池雄一, 佐々木雄彦, 村上誠, 矢作直也編集.2015
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Total Pages
  10
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PROJECT-24590577
[Book] 第6章 3 植物由来成分によるTLR4/MD-2シグナルの抑制. エンドトキシン・自然免疫研究17. 谷徹, 横地高志編集.2014
- Author(s)
  本田裕恵, 長井良憲, 高津聖志
- Total Pages
  6
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-24590577
[Book] 第6章 3 植物由来成分によるTLR4/MD-2シグナルの抑制. エンドトキシン・自然免疫研究17. 谷徹, 横地高志編集.2014
- Author(s)
  本田裕恵, 長井良憲, 高津聖志
- Total Pages
  6
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PUBLICLY-25126707
[Book] Section2. Part E. 26. Role of the immune system in obesity-associated inflammation and insulin resistance. In "Nutrition in the Prevention and Treatment of Abdominal Obesity" (Ronald R. Watson)2014
- Author(s)
  Yoshinori Nagai, Kiyoshi Takatsu
- Total Pages
  13
- Publisher
  ELSEVIER/Academic Press
- Data Source
  KAKENHI-PUBLICLY-24117708
[Book] Section2. Part E. 26. Role of the immune system in obesity-associated inflammation and insulin resistance. In "Nutrition in the Prevention and Treatment of Abdominal Obesity" (Ronald R. Watson)2014
- Author(s)
  Yoshinori Nagai, Kiyoshi Takatsu
- Total Pages
  13
- Publisher
  ELSEVIER/Academic Press
- Data Source
  KAKENHI-PUBLICLY-25126707
[Book] Section2. Part E. 26. Role of the immune system in obesity-associated inflammation and insulin resistance. In "Nutrition in the Prevention and Treatment of Abdominal Obesity" (Ronald R. Watson)2014
- Author(s)
  Yoshinori Nagai, Kiyoshi Takatsu
- Total Pages
  13
- Publisher
  ELSEVIER/Academic Press
- Data Source
  KAKENHI-PROJECT-24590577
[Book] 第6章 3 植物由来成分によるTLR4/MD-2シグナルの抑制. エンドトキシン・自然免疫研究17. 谷徹, 横地高志編集.2014
- Author(s)
  本田裕恵, 長井良憲, 高津聖志
- Total Pages
  6
- Publisher
  医学図書出版株式会社
- Data Source
  KAKENHI-PROJECT-24390119
[Book] Section2. Part E. 26. Role of the immune system in obesity-associated inflammation and insulin resistance. In "Nutrition in the Prevention and Treatment of Abdominal Obesity" (Ronald R. Watson)2014
- Author(s)
  Yoshinori Nagai, Kiyoshi Takatsu
- Total Pages
  13
- Publisher
  ELSEVIER/Academic Press
- Data Source
  KAKENHI-PROJECT-24390119
[Book] 第4項IL-5.seriesモデル動物利用マニュアル疾患モデルの作製と利用-免疫疾患(岩倉洋一郎編集)2011
- Author(s)
  長井良憲、高津聖志
- Total Pages
  4
- Publisher
  株式会社エル・アイ・シー
- Data Source
  KAKENHI-PUBLICLY-22117509
[Book] インターロイキン、インターロイキン受容体「分子細胞生物学辞典」第2版2009
- Author(s)
  長井良憲, ら
- Publisher
  東京化学同人
- Data Source
  KAKENHI-PROJECT-19790354
[Book] TLRシグナルとクラススイッチ組換え臨床免疫・アレルギー科492008
- Author(s)
  長井良憲, 塚本裕美子, 高津聖志
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-16109004
[Book] 臨床免疫・アレルギー科Vo.49 No.3 TLRシグナルとクラススイッチ組換え2008
- Author(s)
  長井良憲
- Total Pages
  6
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19790354
[Book] 免疫とは「臨床アレルギー学アレルギー専門医研修のために改訂第3版2007
- Author(s)
  長井良憲、高津聖志
- Total Pages
  3
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-16109004
[Book] 免疫とは「臨床アレルギー学アレルギー専門医研修のために」改訂第3版2007
- Author(s)
  長井良憲、高津聖志
- Total Pages
  3
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19790354
[Book] 臨床免疫・アレルギー科 Vo.47 No.5 自然免疫系細胞への分化におけるTLRの役割2007
- Author(s)
  長井良憲
- Total Pages
  9
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-19790354
[Book] 免疫総論「免疫とは」臨床アレルギー学(改訂第3版)2007
- Author(s)
  長井良憲, 高津聖志
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-19790354
[Journal Article] Impact of Vancomycin Treatment and Gut Microbiota on Bile Acid Metabolism and the Development of Non-Alcoholic Steatohepatitis in Mice2023
- Author(s)
  Kasai Kaichi、Igarashi Naoya、Tada Yuki、Kani Koudai、Takano Shun、Yanagibashi Tsutomu、Usui-Kawanishi Fumitake、Fujisaka Shiho、Watanabe Shiro、Ichimura-Shimizu Mayuko、Takatsu Kiyoshi、Tobe Kazuyuki、Tsuneyama Koichi、Furusawa Yukihiro、Nagai Yoshinori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 4050-4050
- DOI
  10.3390/ijms24044050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05466, KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-20K19676
[Journal Article] Effect of Oral Administration of Polyethylene Glycol 400 on Gut Microbiota Composition and Diet-Induced Obesity in Mice2023
- Author(s)
  Ishibashi Riko、Matsuhisa Rio、Nomoto Mio、Chudan Seita、Nishikawa Miyu、Tabuchi Yoshiaki、Ikushiro Shinichi、Nagai Yoshinori、Furusawa Yukihiro
- Journal Title
  
  Microorganisms
  
  Volume: 11 Issue: 8 Pages: 1882-1882
- DOI
  10.3390/microorganisms11081882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07005
[Journal Article] The innate immune receptor RP105 promotes metabolic syndrome by altering gut microbiota composition and intestinal barrier function2023
- Author(s)
  Kani Koudai、Kasai Kaichi、Tada Yuki、Ishibashi Riko、Takano Shun、Igarashi Naoya、Ichimura-Shimizu Mayuko、Tsuneyama Koichi、Furusawa Yukihiro、Nagai Yoshinori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 664 Pages: 77-85
- DOI
  10.1016/j.bbrc.2023.04.068
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-22K07024
[Journal Article] Isoxanthohumol improves obesity and glucose metabolism via inhibiting intestinal lipid absorption with a bloom of Akkermansia muciniphila in mice2023
- Author(s)
  Watanabe Yoshiyuki、Fujisaka Shiho、Morinaga Yoshitomo、Watanabe Shiro、Nawaz Allah、Hatta Hideki、Kado Tomonobu、Nishimura Ayumi、Bilal Muhammad、Aslam Muhammad Rahil、Honda Keiko、Nakagawa Yoshimi、Softic Samir、Hirabayashi Kenichi、Nakagawa Takashi、Nagai Yoshinori、Tobe Kazuyuki
- Journal Title
  
  Molecular Metabolism
  
  Volume: 77 Pages: 101797-101797
- DOI
  10.1016/j.molmet.2023.101797
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16424, KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-23K24762
[Journal Article] Dynamics of Liver Macrophage Subsets in a Novel Mouse Model of Non-Alcoholic Steatohepatitis Using C57BL/6 Mice2023
- Author(s)
  Makiuchi Nana、Takano Shun、Tada Yuki、Kasai Kaichi、Igarashi Naoya、Kani Koudai、Kato Miyuna、Goto Kana、Matsuura Yudai、Ichimura-Shimizu Mayuko、Furusawa Yukihiro、Tsuneyama Koichi、Nagai Yoshinori
- Journal Title
  
  Biomedicines
  
  Volume: 11 Issue: 10 Pages: 2659-2659
- DOI
  10.3390/biomedicines11102659
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-22K07024
[Journal Article] High‐Density Lipoprotein Engineering for Eye‐Drop Treatment of Age‐Related Macular Degeneration2023
- Author(s)
  Fukuda Ryosuke、Mahmuda Nargis、Kasirawat Sawangrat、Kawakami Ryo、Shima Rumina、Mizukami Yu、Shibukawa Shiori、Tada Yuki、Kawanishi Fumitake、Ogura Masatsune、Matsuki Kota、Nagai Yoshinori、Nakano Eri、Suda Kenji、Tsujikawa Akitaka、Murakami Tatsuya
- Journal Title
  
  Advanced Therapeutics
  
  Volume: 6 Issue: 11 Pages: 2300186-2300186
- DOI
  10.1002/adtp.202300186
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07005, KAKENHI-PLANNED-20H05842
[Journal Article] The Impact of Low‐Viscosity Soluble Dietary Fibers on Intestinal Microenvironment and Experimental Colitis: A Possible Preventive Application of Alpha‐Cyclodextrin in Intestinal Inflammation2022
- Author(s)
  Yamanouchi Yuka、Chudan Seita、Ishibashi Riko、Ohue‐Kitano Ryuji、Nishikawa Miyu、Tabuchi Yoshiaki、Kimura Ikuo、Nagai Yoshinori、Ikushiro Shinichi、Furusawa Yukihiro
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: 66 Issue: 22 Pages: 2200063-2200063
- DOI
  10.1002/mnfr.202200063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-20K05929, KAKENHI-PROJECT-20K11600
[Journal Article] Roles of Macrophages in Advanced Liver Fibrosis, Identified Using a Newly Established Mouse Model of Diet-Induced Non-Alcoholic Steatohepatitis2022
- Author(s)
  Tada Yuki、Kasai Kaichi、Makiuchi Nana、Igarashi Naoya、Kani Koudai、Takano Shun、Honda Hiroe、Yanagibashi Tsutomu、Watanabe Yasuharu、Usui-Kawanishi Fumitake、Furusawa Yukihiro、Ichimura-Shimizu Mayuko、Tabuchi Yoshiaki、Takatsu Kiyoshi、Tsuneyama Koichi、Nagai Yoshinori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Issue: 21 Pages: 13251-13251
- DOI
  10.3390/ijms232113251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05466, KAKENHI-PROJECT-22K06627, KAKENHI-PROJECT-22K07005, KAKENHI-PROJECT-22K08685
[Journal Article] Isoliquiritigenin Attenuates Adipose Tissue Inflammation and Metabolic Syndrome by Modifying Gut Bacteria Composition in Mice2022
- Author(s)
  Ishibashi Riko、Furusawa Yukihiro、Honda Hiroe、Watanabe Yasuharu、Fujisaka Shiho、Nishikawa Miyu、Ikushiro Shinichi、Kurihara Shin、Tabuchi Yoshiaki、Tobe Kazuyuki、Takatsu Kiyoshi、Nagai Yoshinori
- Journal Title
  
  Molecular Nutrition & Food Research
  
  Volume: - Issue: 10 Pages: 2101119-2101119
- DOI
  10.1002/mnfr.202101119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07076, KAKENHI-PROJECT-19K09019, KAKENHI-PROJECT-20H03730, KAKENHI-PROJECT-20K08882, KAKENHI-PROJECT-22K07005
[Journal Article] 肥満に伴う内臓脂肪組織炎症とメタボリック症候群における好中球の役割2018
- Author(s)
  渡邉康春、長井良憲、髙津聖志
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: ６９ Pages: 434-441
- Data Source
  KAKENHI-PROJECT-16K19532
[Journal Article] Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex2017
- Author(s)
  Okamoto N, Mizote K, Honda H, Saeki A, Watanabe Y, Yamaguchi-Miyamoto T, Fukui R, Tanimura N, Motoi Y, Akashi-Takamura S, Kato T, Fujishita S, Kimura T, Ohto U, Shimizu T, Hirokawa T, Miyake K, Fukase K, Fujimoto Y, Nagai Y, Takatsu K
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 292 Issue: 37 Pages: 15378-15394
- DOI
  10.1074/jbc.m117.791780
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19532, KAKENHI-PLANNED-15H05836, KAKENHI-PUBLICLY-17H05991, KAKENHI-PROJECT-16H01885, KAKENHI-PROJECT-17H02207, KAKENHI-PROJECT-15K07960, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-16K19596, KAKENHI-PROJECT-15K09491
[Journal Article] Eplerenone prevented obesity-induced inflammasome activation and glucose intolerance2017
- Author(s)
  Wada T, Ishikawa A, Watanabe E, Nakamura Y, Aruga Y, Hasegawa H, Onogi Y, Honda H, Nagai Y, Takatsu K, Ishii Y, Sasahara M, Koya D, Tsuneki H, Sasaoka T
- Journal Title
  
  J Endocrinol.
  
  Volume: 235 Issue: 3 Pages: 179-191
- DOI
  10.1530/joe-17-0351
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15472, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K07960, KAKENHI-PROJECT-15K08527
[Journal Article] A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS.2017
- Author(s)
  S. Yamamoto, M. Muramatsu, E. Azuma, M. Ikutani, Y. Nagai, H. Sagara, B.N. Koo, S. Kita, E. O’Donnell, T. Osawa, H. Takahashi, K.I. Takano, M. Dohmoto, M. Sugimori, I. Usui, Y. Watanabe, N. Hatakeyama, T. Iwamoto, I. Komuro, K. Takatsu, K. Tobe, S. Niida, N. Matsuda, M. Shibuya, M. Sasahara
- Journal Title
  
  Sci Rep
  
  Volume: 7：3855 Issue: 1 Pages: 1-16
- DOI
  10.1038/s41598-017-03994-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08565, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K15622, KAKENHI-PROJECT-26710005, KAKENHI-PUBLICLY-16H01567, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-16K14605
[Journal Article] CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors2017
- Author(s)
  Nawaz Allah, , Usui Isao, , et al
- Journal Title
  
  Nature Communications
  
  Volume: 8 Issue: 1 Pages: 286-301
- DOI
  10.1038/s41467-017-00231-1
- NAID
  120006535075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-17K09821, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K08527
[Journal Article] Allergic diseases: From bench to clinic - Contribution of the discovery of interleukin-52017
- Author(s)
  Yanagibashi T、Satoh M、Nagai Y、Koike M、Takatsu K
- Journal Title
  
  Cytokine
  
  Volume: 98 Pages: 59-70
- DOI
  10.1016/j.cyto.2016.11.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-15K18706
[Journal Article] Glycyrrhetinic acid inhibits contact hypersensitivity induced by trichophytin via dectin-12016
- Author(s)
  Tomoya Nakamura, Akiko Nishibu, Naoki Yoshida, Mitsue Yasoshima, Kazushi Anzawa, Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu, Kazuo Ogawa, Takashi Mochizuki
- Journal Title
  
  Experimental Dermatology
  
  Volume: 25 Issue: 4 Pages: 299-304
- DOI
  10.1111/exd.12931
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-25870257
[Journal Article] Fetal lymphoid progenitors become restricted to B-1 fates coincident with IL-7Rα expression2016
- Author(s)
  Iida R, Shinoda K, Hattori Y, Nagai Y, Takatsu K, Kouro T
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 10 Pages: e0165676-e0165676
- DOI
  10.1371/journal.pone.0165676
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08527
[Journal Article] Potential therapeutic natural products for the treatment of obesity-associated inflammation by targeting TLRs and inflammasomes2016
- Author(s)
  Nagai Y, Honda H, Watanabe Y, Takatsu K
- Journal Title
  
  Chronic Inflammation -Mechanisms and Regulation-
  
  Volume: なし Pages: 379-397
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08527
[Journal Article] Deletion of SIRT1 in myeloid cells impairs glucose metabolism with enhancing inflammatory response to adipose tissue hypoxia2016
- Author(s)
  Akiko Takikawa, Isao Usui , Shiho Fujisaka, Masashi Ikutani, Satoko Senda, Shinpei Hattori, Koichi Tsuneyama, Yukiko Koshimizu, Ran Inoue, Ayumi Tanaka-Hayashi, Takashi Nakagawa, Yoshinori Nagai, Kiyoshi Takatsu, Toshiyasu Sasaoka, Hisashi Mori, Kazuyuki Tobe
- Journal Title
  
  Diabetology International
  
  Volume: 7 Issue: 1 Pages: 59-68
- DOI
  10.1007/s13340-015-0213-3
- NAID
  40020774323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-25461333, KAKENHI-PROJECT-24689019, KAKENHI-PROJECT-26461327
[Journal Article] Inflammatory responses increase secretion of MD-1 protein2016
- Author(s)
  Thomas Jennings R, Odkhuu E, Nakashima A, Morita N, Kobayashi T, Yamai I, Tanaka M, Suganami T, Haga S, Ozaki M, Watanabe Y, Nagai Y, Takatsu K, Kikuchi-Ueda T, Ichimonji I, Ogawa Y, Takagi H, Yamazaki T, Miyake K, Akashi-Takamura S
- Journal Title
  
  International Immunology
  
  Volume: 28 Issue: 10 Pages: 503-512
- DOI
  10.1093/intimm/dxw031
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-15K09423, KAKENHI-PROJECT-15K09491, KAKENHI-PROJECT-16K19532
[Journal Article] Isoliquiritigenin attenuates adipose tissue inflammation in vitro and adipose tissue fibrosis through inhibition of innate immune responses in mice.2016
- Author(s)
  Watanabe Y, Nagai Y, Honda H, Okamoto N, Yamamoto S, Hamashima T, Ishii Y, Tanaka M, Suganami T, Sasahara M, Miyake, K, Takatsu K.
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 23097-23097
- DOI
  10.1038/srep23097
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07960, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-15K09423, KAKENHI-PUBLICLY-15H01371, KAKENHI-PROJECT-25870257, KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-26460360
[Journal Article] HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.2016
- Author(s)
  Takikawa A, Mahmood A, Nawaz A, Kado T, Okabe K, Yamamoto S, Arif A, Senda S, Tsuneyama K, Ikutani M, Watanabe Y, Igarashi Y, Nagai Y, Takatsu K, Koizumi K, Imura J, Goda N, Sasahara M, Matsumoto M, Saeki K, Nakagawa T, Fujisaka S, Usui I, Tobe K.
- Journal Title
  
  Diabetes
  
  Volume: 65(12) Issue: 12 Pages: 3649-3659
- DOI
  10.2337/db16-0012
- NAID
  40021380120
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293093, KAKENHI-PROJECT-26460360, KAKENHI-PROJECT-26461327, KAKENHI-PROJECT-15K08527, KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-16K19532
[Journal Article] 自然免疫系センサーによる慢性炎症制御とメタボリック症候群2015
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Journal Title
  
  別冊BIO Clinica 慢性炎症と疾患「慢性炎症制御による加齢関係疾患治療の展望」
  
  Volume: 4 Pages: 67-72
- Data Source
  KAKENHI-PROJECT-15K08527
[Journal Article] Increased production of intestinal immunoglobulins in Syntenin-1-deficient mice.2015
- Author(s)
  Tamura K., Ikutani M., Yoshida T., Tanaka-Hayashi A., Yanagibashi T., Inoue R., Nagai Y., Adachi Y., Miyawaki T., Takatsu K., Mori H.
- Journal Title
  
  Immunobiology
  
  Volume: 220 Issue: 5 Pages: 597-604
- DOI
  10.1016/j.imbio.2014.12.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-221S0003
[Journal Article] Differential requirements of MyD88 And TRIF pathways in TLR4-mediated immune responses in murine B cells.2015
- Author(s)
  Yanagibashi T., Nagai Y., Watanabe Y., Ikutani M., Hirai Y., Takatsu K.
- Journal Title
  
  Immunology Letters
  
  Volume: 163 Issue: 1 Pages: 22-31
- DOI
  10.1016/j.imlet.2014.11.012
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25870257
[Journal Article] Inflammation-induced endothelial cell-derived extracellukar vesicles modulate the cellular status of pericytes.2015
- Author(s)
  Yamamoto S., Niida S., Azuma E., Yanagibashi T., Muramatsu M., Huang TT., Sagara H., Higaki S., Ikutani M., Nagai Y., Takatsu K., Miyazaki K., Hamashima T., Mori H., Matsuda N., Ishii Y., Sasahara M.
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 8505-8505
- DOI
  10.1038/srep08505
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25293365, KAKENHI-PROJECT-15K08396, KAKENHI-PROJECT-26460360, KAKENHI-PROJECT-25293093
[Journal Article] Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation.2014
- Author(s)
  Honda H., Nagai Y., Matsunaga T., Okamoto N., Watanabe Y., Tsuneyama K., Hayashi H., Fujii I., Ikutani M., Hirai Y., Muraguchi A., Takatsu K.
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 96 Issue: 6 Pages: 1087-1100
- DOI
  10.1189/jlb.3a0114-005rr
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25670175, KAKENHI-PROJECT-25870257
[Journal Article] Deficiency of nicotinamide mononucleotide adenylyltransferase 3 (nmnat3) causes Hemolytic anemia by altering the glycolytic flow in mature erythrocytes.2014
- Author(s)
  Hikosaka K., Ikutani M., Shito M., Kazuma K., Gulshan M., Nagai Y., Takatsu K., Konno K., Tobe K., Kanno H., Nakagawa T.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Issue: 21 Pages: 14796-14811
- DOI
  10.1074/jbc.m114.554378
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25461609, KAKENHI-PROJECT-26461327
[Journal Article] 自然免疫系受容体RP105/MD-1によるメタボリック症候群の制御2013
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 37 Pages: 611-616
- Data Source
  KAKENHI-PUBLICLY-25126707
[Journal Article] The TLR family protein RP105/MD-1 complex: a new player in obesity and adipose tissue inflammation2013
- Author(s)
  Yoshinori Nagai, Yasuharu Watanabe, Kiyoshi Takatsu
- Journal Title
  
  Adipocyte
  
  Volume: 2 Issue: 2 Pages: 61-66
- DOI
  10.4161/adip.22929
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117708, KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25870257
[Journal Article] Screening of natural compounds for the restorative activity against immunosuppression by tumor cells (2)2013
- Author(s)
  Ogasawara M, Yamasaki S, Miyamoto T, Masashi I，Nagai Y, Matsunaga T
- Journal Title
  
  Annual Report of Toyama Pref. Inst. for Pharm. Res.
  
  Volume: 40 Pages: 22-46
- Data Source
  KAKENHI-PROJECT-24590109
[Journal Article] 自然免疫系受容体RP105/MD-1によるメタボリック症候群の制御2013
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 37 Pages: 611-616
- Data Source
  KAKENHI-PROJECT-24390119
[Journal Article] 自然免疫系受容体RP105/MD-1によるメタボリック症候群の制御2013
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 37 Pages: 611-616
- Data Source
  KAKENHI-PUBLICLY-24117708
[Journal Article] Adipose Tissue Hypoxia Induces Inflammatory M1 Polarity of Macrophages in HIF-1a-Dependent and HIF-1a-Independent Manners in Obese Mice.2013
- Author(s)
  Fujisaka S, Usui I, Ikutani M, Aminuddin A, Takikawa A, Tsuneyama K, Mahmood A, Goda N, Nagai Y, Takatsu K, Tobe K..
- Journal Title
  
  Diabetologia
  
  Volume: 56(6) Issue: 6 Pages: 1403-1412
- DOI
  10.1007/s00125-013-2885-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590370, KAKENHI-PUBLICLY-24117708, KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24390181, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25461333
[Journal Article] Activation and regulation of the pattern recognition receptors in obesity-induced adipose tissue inflammation and insulin resistance2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Journal Title
  
  Nutrients
  
  Volume: 5 Issue: 9 Pages: 3757-3778
- DOI
  10.3390/nu5093757
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-24117708, KAKENHI-PROJECT-24390119, KAKENHI-PROJECT-24590577, KAKENHI-PUBLICLY-25126707, KAKENHI-PROJECT-25870257
[Journal Article] 自然免疫系受容体RP105/MD-1によるメタボリック症候群の制御2013
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 37 Pages: 611-616
- Data Source
  KAKENHI-PROJECT-24590577
[Journal Article] The RP105/MD-1 complex is indispensable for TLR4/MD-2-dependent proliferation and IgM-secreting plasma cell differentiation of marginal zone B cells2012
- Author(s)
  Yoshinori Nagai
- Journal Title
  
  International Immunology
  
  Volume: (in press) Issue: 6 Pages: 389-400
- DOI
  10.1093/intimm/dxs040
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591283, KAKENHI-PUBLICLY-22117509, KAKENHI-PROJECT-24590577, KAKENHI-PROJECT-24591466, KAKENHI-PLANNED-21117002
[Journal Article] Screening of natural compounds for the restorative activity against immunosuppression by tumor cells.2012
- Author(s)
  Ogasawara M, Yamasaki S, Miyamoto T, Nagai Y, Matsunaga T
- Journal Title
  
  Annual Report of Toyama Pref. Inst. for Pharm. Res.
  
  Volume: 39 Pages: 21-25
- Data Source
  KAKENHI-PROJECT-24590109
[Journal Article] The Radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation2012
- Author(s)
  Y. Watanabe, T. Nakamura, S. Ishikawa, S. Fujisaka, I. Usui, K. Tsuneyama, Y. Ichihara, T. Wada, Y. Hirata, T. Suganami, H. Izaki, S. Akira, K. Miyake, H. Kanayama, M. Shimabukuro, M. Sata, T. Sasaoka, Y. Ogawa, K. Tobe, K. Takatsu, Y. Nagai
- Journal Title
  
  Diabetes
  
  Volume: 61 Issue: 5 Pages: 1199-1209
- DOI
  10.2337/db11-1182
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-21117007, KAKENHI-PUBLICLY-22117509, KAKENHI-PROJECT-22390159, KAKENHI-PROJECT-22590971, KAKENHI-PROJECT-23591314, KAKENHI-PROJECT-23659247, KAKENHI-PROJECT-23659420, KAKENHI-PROJECT-24659392, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117708
[Journal Article] Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRL(lpr/lpr) mice2012
- Author(s)
  Sasaki S.
- Journal Title
  
  Mol Immunol
  
  Volume: 49(4) Issue: 4 Pages: 611-620
- DOI
  10.1016/j.molimm.2011.10.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590433, KAKENHI-PROJECT-21790463, KAKENHI-PROJECT-23659247, KAKENHI-PROJECT-24390181
[Journal Article] Glycyrrhizin and isoliquiritigenin suppress the LPS sensor Toll-like receptor 4/MD-2 complex signaling in a different manner2012
- Author(s)
  Honda, H., et al
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: (in press) Issue: 6 Pages: 967-976
- DOI
  10.1189/jlb.0112038
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22117509, KAKENHI-PROJECT-23390264, KAKENHI-PROJECT-23590564, KAKENHI-PROJECT-23659247, KAKENHI-PLANNED-21117002, KAKENHI-PUBLICLY-24117706
[Journal Article] Analysis of Trichophyton antigen-induced contact hypersensitivity in mouse2012
- Author(s)
  Nakamura, T., Nagai, Y
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 66-2 Pages: 144-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790463
[Journal Article] Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRLlpr/lpr mice2012
- Author(s)
  Sasaki, S., Nagai, Y
- Journal Title
  
  Molecular Immunology
  
  Volume: 49 Pages: 611-620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790463
[Journal Article] Identification of innate IL-5-producing cells and their role in lung eosinophil regulation and antitumor immunity2012
- Author(s)
  Ikutani M.
- Journal Title
  
  J Immunol
  
  Volume: 188(2) Issue: 2 Pages: 703-713
- DOI
  10.4049/jimmunol.1101270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590433, KAKENHI-PUBLICLY-22117509, KAKENHI-PROJECT-22590446, KAKENHI-PROJECT-22590447, KAKENHI-PROJECT-23659247, KAKENHI-PUBLICLY-23122506
[Journal Article] Identification of FOXP3-negative regulatory T-like(CD4+CD25+CD127low) cells on patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome2011
- Author(s)
  Otsubo, K., Nagai, Y
- Journal Title
  
  Clinical Immunology
  
  Volume: 141 Pages: 111-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790463
[Journal Article] アジュバントと自然免疫制御新たな展開と疾患の制御2010
- Author(s)
  長井良憲
- Journal Title
  
  ファルマシア 46
  
  Pages: 61-65
- NAID
  110009867587
- Data Source
  KAKENHI-PROJECT-17013024
[Journal Article] IL-5と好酸球で誘導されるアレルギー性炎症2009
- Author(s)
  長井良憲、高津聖志
- Journal Title
  
  実験医学増刊号「アレルギー疾患の免疫制御」 Vol.27
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-20390141
[Journal Article] Regulatory mechanism for adipose tissue M1 and M2 macrophages in diet-induced obese mice.2009
- Author(s)
  Fujisaka S., Ikutani M., Nagai Y., Takatsu K.
- Journal Title
  
  Diabetes Vol.58
  
  Pages: 2574-2682
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390141
[Journal Article] Interleukin 5 in the link between the innate and acquired immune response2009
- Author(s)
  Takatsu K, Kouro T, Nagai Y
- Journal Title
  
  Advances in Immunology 101
  
  Pages: 191-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013024
[Journal Article] Toll-like receptor 7 cooperates with antigen receptors and CD38 for induction of class switch recombination and terminal B cell maturation.2009
- Author(s)
  Tsukamoto Y., Nagai Y., Kaisho T., Takatsu K.
- Journal Title
  
  Mol.Immunol. Vol.46
  
  Pages: 1276-1288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390141
[Journal Article] Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production2009
- Author(s)
  Tsukamoto Y, Nagai Y, Kariyone A, Shibata T, Kaisho T, Akira S, Miyake K, Takatsu K
- Journal Title
  
  Mol. Immunol 46
  
  Pages: 1278-1288
- Data Source
  KAKENHI-PROJECT-16109004
[Journal Article] Role of IL-5 in the Immune response to inflammation2009
- Author(s)
  Takatsu K, Kouro T, Nagai Y
- Journal Title
  
  Adv. Immunol 101
  
  Pages: 191-236
- Data Source
  KAKENHI-PROJECT-16109004
[Journal Article] Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production2009
- Author(s)
  Tsukamoto, Y., Nagai, Y
- Journal Title
  
  Molecular Immunology
  
  Volume: 46 Pages: 1278-1288
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790463
[Journal Article] IL-5と好酸球で誘導されるアレルギー性炎症2009
- Author(s)
  長井良憲、高津聖志
- Journal Title
  
  実験医学増刊「アレルギー疾患の免疫機構」 27
  
  Pages: 107-113
- Data Source
  KAKENHI-PROJECT-20390141
[Journal Article] Tonic B cell activation by Radioprotective 105/MD-1 promotes disease progression in MRL/lpr mice. Int2008
- Author(s)
  Kobayashi, T., K. Takahashi, Y. Nagai, T. Shibata, M. Otani, S. Izui, S. Akira, Y. Gotoh, H. Kiyono, K. Miyake.
- Journal Title
  
  Immunol. 20(7)
  
  Pages: 881-891
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790354
[Journal Article] TLRシグナルとクラススイッチ組換え2008
- Author(s)
  長井良憲, 塚本裕美子, 高津聖志
- Journal Title
  
  臨床免疫・アレルギー科 49(3)
  
  Pages: 246-251
- Data Source
  KAKENHI-PROJECT-19790354
[Journal Article] Lymphoid precursors are directed to produce dendritic cells as a result of TLR9 ligation during herpes infection2008
- Author(s)
  Welner, R.S., R. Pelayo, Y. Nagai, K.P. Garrett, T.R. Wuest, D.J. Carr, L.A. Borghesi, M.A. Farrar, P.W. Kincade
- Journal Title
  
  Blood 112(9)
  
  Pages: 3753-3761
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790354
[Journal Article] A protein associated with Toll-like receptor 4 (PRAT4A) is required for TLR-dependent immune responses2007
- Author(s)
  Takahashi, K., T. Shibata, S. Akashi-Takamura, T. Kiyokawa, Y. Wakabayashi, N. Tanimura, T. Kobayashi, F. Matsumoto, R. Fukui, T. Kouro, Y. Nagai, K. Takatsu, S. S-I. Saitoh, K. Miyake.
- Journal Title
  
  J. Exp. Med. 204(12)
  
  Pages: 2963-2976
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790354
[Journal Article] 自然免疫系細胞への分化におけるTLRの役割2007
- Author(s)
  長井良憲
- Journal Title
  
  臨床免疫・アレルギー科 47(5)
  
  Pages: 610-618
- NAID
  40015525631
- Data Source
  KAKENHI-PROJECT-19790354
[Journal Article] Toll-like receptors on Heamtopoietic progenitor cells stimulate innate immune system replenishment2006
- Author(s)
  Nagai Y, Garrett KP, Ohta S, Bahrun U, Kouro T, Akira S, Takatsu K, Kincade PW
- Journal Title
  
  Immunity 24
  
  Pages: 801-812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17013024
[Journal Article] Toll-like receptors on hematopoietic ptogenitor cells stimulate innate immune system replenishment2006
- Author(s)
  Nagai Y, et. al.
- Journal Title
  
  Immunity 24
  
  Pages: 801-812
- Data Source
  KAKENHI-PROJECT-17013024
[Journal Article] The radioprotective 105/MD-1 complex links TLR2 and TLR4/MD-2 in antibody response to microbial membranes.2005
- Author(s)
  Nagai Y et al.
- Journal Title
  
  Journal of Immunology 174・11
  
  Pages: 7043-7049
- Data Source
  KAKENHI-PROJECT-17013024
[Journal Article] Radioprotectiv 105-MD-1 links toll-like receptors 2 (TLR2) and TLR4-MD2 with antibody production to microbial membrane.2005
- Author(s)
  Nagai Y
- Journal Title
  
  J.Immunol. 174
  
  Pages: 7043-7049
- Data Source
  KAKENHI-PROJECT-16109004
[Patent] IL-1及びTNF活性阻害剤2014
- Inventor(s)
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Holder
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Type
  特許
- Filing Date
  2014-12-24
- Overseas
- Data Source
  KAKENHI-PUBLICLY-25126707
[Patent] IL-1及びTNF活性阻害剤2014
- Inventor(s)
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Holder
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Type
  特許
- Filing Date
  2014-12-24
- Overseas
- Data Source
  KAKENHI-PROJECT-24390119
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2014
- Inventor(s)
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-201593
- Filing Date
  2014-09-30
- Data Source
  KAKENHI-PROJECT-24390119
[Patent] IL-1及びTNF活性阻害剤2014
- Inventor(s)
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Holder
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Type
  特許
- Filing Date
  2014-12-24
- Overseas
- Data Source
  KAKENHI-PROJECT-24590577
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2014
- Inventor(s)
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-201593
- Filing Date
  2014-09-30
- Data Source
  KAKENHI-PUBLICLY-25126707
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2014
- Inventor(s)
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-201593
- Filing Date
  2014-09-30
- Data Source
  KAKENHI-PROJECT-24590577
[Patent] IL-1及びTNF活性阻害剤2013
- Inventor(s)
  高津聖志、平井嘉勝、長井良憲、松永孝之
- Industrial Property Rights Holder
  高津聖志、平井嘉勝、長井良憲、松永孝之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-271897
- Filing Date
  2013-12-27
- Data Source
  KAKENHI-PROJECT-24590577
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2013
- Inventor(s)
  藤本ゆかり、深瀬浩一、高津聖志、長井良憲、岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり、深瀬浩一、高津聖志、長井良憲、岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-203801
- Filing Date
  2013-09-30
- Data Source
  KAKENHI-PROJECT-24590577
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2013
- Inventor(s)
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-203801
- Filing Date
  2013-09-30
- Data Source
  KAKENHI-PROJECT-24390119
[Patent] IL-1及びTNF活性阻害剤2013
- Inventor(s)
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Holder
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-271897
- Filing Date
  2013-12-27
- Data Source
  KAKENHI-PROJECT-24390119
[Patent] IL-1及びTNF活性阻害剤2013
- Inventor(s)
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Holder
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-271897
- Filing Date
  2013-12-27
- Data Source
  KAKENHI-PUBLICLY-24117708
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2013
- Inventor(s)
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-203801
- Filing Date
  2013-09-30
- Data Source
  KAKENHI-PUBLICLY-25126707
[Patent] IL-1及びTNF活性阻害剤2013
- Inventor(s)
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Holder
  髙津聖志，平井嘉勝，長井良憲，松永孝之
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-271897
- Filing Date
  2013-12-27
- Data Source
  KAKENHI-PUBLICLY-25126707
[Patent] トール様受容体4活性化作用を有するフニクロシン誘導体及びその用途2013
- Inventor(s)
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Holder
  藤本ゆかり，深瀬浩一，髙津聖志，長井良憲，岡本直樹
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-203801
- Filing Date
  2013-09-30
- Data Source
  KAKENHI-PUBLICLY-24117708
[Patent] インフラマソーム活性制御剤2012
- Inventor(s)
  高津聖志、平井嘉勝、長井良憲、松永孝之、本田裕恵
- Industrial Property Rights Holder
  富山大学、富山県薬事研究所
- Industrial Property Number
  2012-247766
- Filing Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-23659247
[Patent] インフラマソーム活性制御剤2012
- Inventor(s)
  高津聖志, 平井嘉勝, 長井良憲, 松永孝之, 本田裕恵
- Industrial Property Rights Holder
  富山大学富山県薬事研究所
- Industrial Property Number
  2012-247766
- Filing Date
  2012-11-09
- Data Source
  KAKENHI-PROJECT-24390119
[Patent] リガンド探索用細胞、リガンド探索方法、抗肥満薬または抗メタボリックシンドローム薬探索用細胞2010
- Inventor(s)
  高津聖志, 長井良憲
- Industrial Property Rights Holder
  富山大学
- Industrial Property Number
  2010-147034
- Filing Date
  2010-06-24
- Data Source
  KAKENHI-PUBLICLY-22117509
[Presentation] The innate immune receptor RP105 induces metabolic syndrome by intestinal barrier dysfunction and alteration of gut microbial composition2024
- Author(s)
  Kani K, Furusawa Y, Tsuneyama K, Nagai Y
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Impact of the gut microbiota and their metabolites on the development of non-alcoholic steatohepatitis in type 2 diabetic TSOD mice and their control TSNO mice2024
- Author(s)
  Igarashi N, Furusawa Y, Tsuneyama K, Nagai Y
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Modulation of gut microbiota by antibiotics treatment affect the development of liver inflammation and fibrosis in a novel dietary mouse model of NASH2024
- Author(s)
  Takano S, Furusawa Y, Tsuneyama K, Nagai Y
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 肝臓構成細胞に着目した非アルコール性脂肪性肝炎進展の差異に関する研究2023
- Author(s)
  五十嵐直哉、市村-清水真祐子、常山幸一、長井良憲
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] メタボリックシンドロームにおいて、自然免疫受容体RP105は腸内細菌叢の構成を変化させ、腸管バリア機能の破綻を誘導する2023
- Author(s)
  可児晃大、古澤之裕、市村-清水真祐子、常山幸一、長井良憲
- Organizer
  日本生化学会北陸支部第41回大会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] The innate immune receptor RP105 altered the composition of the gut microbiota and induced the development of metabolic syndrome2023
- Author(s)
  Kani K, Furusawa Y, Nagai Y
- Organizer
  The 7th Toyama-Basel Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 抗生剤投与による腸内細菌叢変化がNASHの発症・病態に与える影響の解析2023
- Author(s)
  髙野峻、市村-清水真祐子、常山幸一、長井良憲
- Organizer
  第59回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 自然免疫受容体RP105は腸内細菌叢の変容及び腸管バリア機能の破綻を誘導し、メタボリックシンドロームの発症に関わる2023
- Author(s)
  可児晃大、古澤之裕、常山幸一、長井良憲
- Organizer
  第44回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 肝臓免疫細胞に着目した非アルコール性脂肪性肝炎進展の差異に関する研究2023
- Author(s)
  五十嵐直哉、市村-清水真祐子、常山幸一、長井良憲
- Organizer
  日本生化学会北陸支部第41回大会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 抗生剤投与による腸内細菌叢変化がNASHの発症・病態に与える影響の解析2023
- Author(s)
  髙野峻、葛西海智、市村-清水真祐子、常山幸一、古澤之裕、長井良憲
- Organizer
  日本生化学会北陸支部第41回大会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Roles of macrophage subsets and gut microbiota in the pathogenesis of non-alcoholic steatohepatitis2023
- Author(s)
  Igarashi N, Furusawa Y, Nagai Y
- Organizer
  The 7th Toyama-Basel Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 新規NASHモデルマウス“3-Fマウス”における肝臓中自然免疫系細胞サブセットの解析2022
- Author(s)
  多田有希, 葛西海智, 市村-清水真祐子, 常山幸一, 長井良憲
- Organizer
  第43回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Differential pathogenesis of non-alcoholic steatohepatitis in type 2 diabetic TSOD mice and their control TSNO mice.2022
- Author(s)
  Igarashi N, Kasai K, Tada Y, Tsuneyama K, Nagai Y
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 非アルコール性脂肪性肝炎の新規モデルマウス“3-Fマウス”における腸内細菌叢及び胆汁酸組成の解析2022
- Author(s)
  葛西海智, 古澤之裕, 多田有希, 五十嵐直哉, 渡辺志朗, 藤坂志帆, 戸邉一之, 市村-清水真祐子, 常山幸一, 長井良憲
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Impact of changes of the gut microbiota on the development of liver inflammation and fibrosis in a novel dietary mouse model of non-alcoholic steatohepatitis, “3-F mice”.2022
- Author(s)
  Kasai K, Furusawa Y, Tada Y, Igarashi N, Tsuneyama K, Nagai Y
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 新規NASHモデルマウス“3-Fマウス”の炎症・線維性変化に与える抗生剤投与の影響2022
- Author(s)
  葛西海智, 多田有希, 五十嵐直哉, 渡辺志朗, 市村-清水真祐子, 常山幸一, 古澤之裕, 長井良憲
- Organizer
  第43回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Analysis of liver macrophage subsets in a novel dietary mouse model of non-alcoholic steatohepatitis, “3-F mice”.2022
- Author(s)
  Tada Y, Kasai K, Makiuchi N, Tsuneyama K, Nagai Y
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] Roles of the innate immune receptor RP105 in the development of nonalcoholic steatohepatitis.2022
- Author(s)
  Takano S, Tada Y, Kasai K, Tsuneyama K, Nagai Y
- Organizer
  第51回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] NASH線維化亢進モデルマウス"3-Fマウス"における腸内細菌叢及び胆汁酸組成の変化2022
- Author(s)
  葛西海智, 市村-清水真祐子, 常山幸一, 長井良憲
- Organizer
  第58回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-22K07005
[Presentation] 糖尿病モデルマウスの内臓脂肪組織に対するイソリクイリチゲニンの抗炎症・抗線維化作用の解析2018
- Author(s)
  本田裕恵, 渡邉康春, 長井良憲, 松永孝之, 岡本直樹, 平井嘉勝, 高津聖志
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] 遊離脂肪酸を起点とした好中球と脂肪細胞との相互作用は、IL-1β産生とマクロファージの内臓脂肪組織浸潤に関与する2018
- Author(s)
  渡邉康春, 長井良憲, 高津聖志
- Organizer
  第39回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] 糖尿病モデルマウスの内臓脂肪組織に対するイソリクイリチゲニンの抗炎症・抗線維化作用の解析2018
- Author(s)
  本田裕恵, 渡邉康春, 長井良憲, 松永孝之, 岡本直樹, 平井嘉勝, 高津聖志
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 糖尿病モデルマウスの内臓脂肪組織に対するイソリクイリチゲニンの抗炎症・抗線維化作用の解析2018
- Author(s)
  本田裕恵, 渡邉康春, 長井良憲, 松永孝之, 岡本直樹, 平井嘉勝, 高津聖志
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-15K07960
[Presentation] Crosstalk between neutrophils and adipocytes exacerbates adipose tissue inflammation in progression of type 2 diabetes2018
- Author(s)
  渡邉康春, 長井良憲, 高津聖志
- Organizer
  第5回富山・バーゼル医薬品研究開発シンポジウム
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] The interaction of neutrophils with adipocytes plays a key role in the infiltration of macrophage into the adipose tissue2017
- Author(s)
  Watanabe Yasuharu, Nagai Yoshinori, Takatsu Kiyoshi
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] The interaction of neutrophils with adipocytes plays a key role in the infiltration of macrophage into the adipose tissue2017
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] IL-5-producing ILC2s in the large intestine contribute to T cell-independent IgA production through the regulation of eosinophil homeostasis2017
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 骨髄移植による副腎白質ジストロフィー発症抑制機構：移植マウス中枢神経系の生化学的解析2017
- Author(s)
  守田雅志，大山拓郎，冨田勇, 螺澤太郎, 松本隼，渡辺志朗, 渡邉康春，長井良憲，高津聖志，山本誠士，石井陽子，笹原正清，今中常雄
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-26
- Data Source
  KAKENHI-PROJECT-16K09961
[Presentation] Funiculosin variants and their synthetic derivatives are novel agonists for murine and human TLR4/MD-2 complex: Potential reagents for developing vaccine adjuvants2017
- Author(s)
  Yoshinori Nagai, Naoki Okamoto, Kiyoshi Takatsu
- Organizer
  Innovation Forums Basel Life 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] Adipose tissue neutrophils are primed by the interaction with adipocytes2016
- Author(s)
  Watanabe Yasuharu, Nagai Yoshinori, Takatsu Kiyoshi
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター・ラグナガーデンホテル(沖縄県宜野湾市)
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] 天然薬物イソリクイリチゲニンは自然免疫系に作用し、内臓脂肪組織の線維化を抑制する2016
- Author(s)
  渡邉康春, 長井良憲, 本田裕恵, 高津聖志
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン(東京都・江東区）
- Data Source
  KAKENHI-PROJECT-15K07960
[Presentation] 甘草成分イソリクイリチゲニンは内臓脂肪組織の炎症・線維化を抑制する2016
- Author(s)
  本田裕恵, 渡邉康春, 長井良憲, 松永孝之, 岡本直樹, 平井嘉勝, 高津聖志
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Data Source
  KAKENHI-PROJECT-15K07960
[Presentation] 甘草成分イソリクイリチゲニンはNLRP3インフラマソーム活性化を阻害し、2型糖尿病の慢性炎症を改善する2016
- Author(s)
  本田裕恵, 長井良憲, 松永孝之, 岡本直樹, 渡邉康春, 常山幸一, 林宏明, 藤井勲, 平井嘉勝, 高津聖志
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K07960
[Presentation] Agonistic effects of synthetic derivatives of funiculosin on mouse/human TLR4/MD-22016
- Author(s)
  Naoki Okamoto, Hiroe Honda, Sachiko Akashi-Takamura, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] Adipose tissue neutrophils are primed by the interaction with adipocytes2016
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] TLRのアダプター分子TRIFを介した視床下部炎症と摂食制御異常の解析2016
- Author(s)
  渡邉康春、長井良憲、高津聖志
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都市勧業館　みやこめっせ(京都府京都市)
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] 甘草成分イソリクイリチゲニンは内臓脂肪組織の炎症・線維化を抑制する2016
- Author(s)
  本田裕恵、渡邉康春、長井良憲、松永孝之、岡本直樹、平井嘉勝、高津聖志
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場(富山県富山市)
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] 骨髄移植による副腎白質ジストロフィー発症抑制機構の解明：レシピエントマウスの生化学的解析2016
- Author(s)
  大山拓郎，冨田　勇, 螺澤太郎, 松本隼，守田雅志，渡辺志朗, 渡邉康春，長井良憲，高津聖志，山本誠士，石井陽子，笹原正清，今中常雄
- Organizer
  日本薬学会北陸支部第128回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-16K09961
[Presentation] TLRのアダプター分子TRIFを介した視床下部炎症と摂食制御異常の解析2016
- Author(s)
  渡邉康春, 長井良憲, 高津聖志
- Organizer
  第37回日本炎症・再生医学会
- Place of Presentation
  京都市勧業館みやこめっせ
- Year and Date
  2016-06-16
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] Agonistic effects of synthetic derivatives of funiculosin on mouse/human TLR4/MD-22016
- Author(s)
  Okamoto N, Honda H, Akashi-Takamura S, Nagai Y, Takatsu K
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄コンベンションセンター（沖縄県・宜野湾市）
- Data Source
  KAKENHI-PROJECT-15K07960
[Presentation] 天然薬物イソリクイリチゲニンは自然免疫系に作用し、内臓脂肪組織の線維化を抑制する2016
- Author(s)
  渡邉康春、長井良憲、本田裕恵、高津聖志
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン(東京都江東区）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] Abcd1欠損マウスへの骨髄移植：レシピエントマウス各組織の生化学的解析2016
- Author(s)
  守田雅志，大山拓郎，冨田　勇，渡邉靖春，長井良憲、渡辺志朗，小林博司，大橋十也，高津聖志，今中常雄
- Organizer
  第58回日本先天代謝異常学会総会
- Place of Presentation
  東京
- Year and Date
  2016-10-27
- Data Source
  KAKENHI-PROJECT-16K09961
[Presentation] 骨髄移植による副腎白質ジストロフィー発症抑制機構の解明：レシピエントマウスの生化学的解析2016
- Author(s)
  大山拓郎、冨田勇、螺澤太郎、松本隼、守田雅志、渡辺志朗、渡邉康春、長井良憲、高津聖志、山本誠二、石井陽子、笹原正清、今中常雄
- Organizer
  第128回薬学会北陸支部会
- Place of Presentation
  北陸大学(石川県金沢市）
- Data Source
  KAKENHI-PROJECT-16K19532
[Presentation] 甘草成分イソリクイリチゲニンは内臓脂肪組織の炎症・線維化を抑制する2016
- Author(s)
  本田裕恵, 渡邉康春, 長井良憲, 松永孝之, 岡本直樹, 平井嘉勝, 高津聖志
- Organizer
  日本生薬学会第63回年会
- Place of Presentation
  富山国際会議場
- Year and Date
  2016-09-24
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 天然薬物イソリクイリチゲニンは自然免疫系に作用し、内臓脂肪組織の線維化を抑制する2016
- Author(s)
  渡邉康春, 長井良憲, 本田裕恵, 高津聖志
- Organizer
  第37回日本肥満学会
- Place of Presentation
  東京ファッションタウン
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 甘草成分イソリクイリチゲニンはNLRP3インフラマソーム活性化を阻害し、2型糖尿病の慢性炎症を改善する2016
- Author(s)
  本田裕恵, 長井良憲, 松永孝之, 岡本直樹, 渡邉康春, 常山幸一, 林宏明, 藤井勲, 平井嘉勝, 高津聖志
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-03-26
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 遊離脂肪酸誘発性の内臓脂肪組織炎症モデルにおける好中球とIL-1βの機能解析2015
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Organizer
  第36回日本炎症・再生医学会
- Place of Presentation
  虎ノ門ヒルズフォーラム
- Year and Date
  2015-07-21
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 遊離脂肪酸誘発性の内臓脂肪組織炎症における好中球の機能解析2015
- Author(s)
  渡邉康春, 長井良憲, 高津聖志
- Organizer
  第36回日本肥満学会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2015-10-02
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] Role of IL-5-producing ILC2s in T cell independent-IgA production in the large intestine2015
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu K
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] Accumulation of and increased IL-1β production by neutrophils in adipose tissue: roles of free fatty acid and leukotriene B42015
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai Y, Kiyoshi Takatsu
- Organizer
  第44回日本免疫学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K08527
[Presentation] 副腎白質ジストロフィーモデルマウスへの骨髄移植とその効果2014
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 山本誠士, 石井陽子, 笹原正清, 高津聖志, 今中常雄
- Organizer
  日本薬学会北陸支部第126回例会
- Place of Presentation
  金沢大学角間キャンパス（金沢）
- Year and Date
  2014-11-16
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 副腎白質ジストロフィー: レンチウイルスベクターを用いたABCD1遺伝子発現と骨髄移植2013
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  平成25年度日本薬学会北陸支部第125回例会
- Place of Presentation
  北陸大学薬学部アネックスファーム（石川）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] The roles of IL-5 producing ILC2 in the intestinal immunity2013
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 甘草成分はTLR4及びNLRP3インフラマソーム活性化を阻害する2013
- Author(s)
  本田裕恵, 長井良憲, 高村（赤司）祥子, 齋藤伸一郎, 三宅健介, 高津聖志
- Organizer
  第19回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  ロイヤルオークホテルスパ＆ガーガーデンズ（滋賀）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] 甘草成分はTLR4及びNLRP3インフラマソーム活性化を阻害する2013
- Author(s)
  本田裕恵, 長井良憲, 高村（赤司）祥子, 齋藤伸一郎, 三宅健介, 高津聖志
- Organizer
  第19回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  ロイヤルオークホテル　スパ＆ガーデンズ（滋賀）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] Isoliquiritigenin and glycyrrhizin inhibit the inflammasome activation in a different manner2013
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  The 100th Annual Meeting of The American Association of Immunologists(第100回アメリカ免疫学会)
- Place of Presentation
  Hawaii Convention Center(アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 腸管免疫におけるIL-5産生ILC2の役割の解明2013
- Author(s)
  生谷尚士, 柳橋努, 長井良憲, 高津聖志
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] 自然免疫受容体TLR4/MD-2複合体の新規リガンド創製を目指したイソプレノイド脂質の構造解析と合成研究2013
- Author(s)
  溝手啓介, 佐伯昭典, 本田裕恵, 岡本直樹, 木村隆仁, 長井良憲, 高津聖志, 藤本ゆかり, 深瀬浩一
- Organizer
  日本化学会秋季事業第3回CSJ化学フェスタ2013
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 腸管免疫におけるIL-5産生ILC2の役割の解明2013
- Author(s)
  生谷尚士, 柳橋努, 長井良憲, 高津聖志
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] 自然免疫受容体TLR4/MD-2複合体の新規リガンド創製を目指したイソプレノイド脂質の構造解析と合成研究2013
- Author(s)
  溝手啓介, 佐伯昭典, 本田裕恵, 岡本直樹, 木村隆仁, 長井良憲, 高津聖志, 藤本ゆかり, 深瀬浩一手啓介, 佐伯昭典, 本田裕恵, 岡本直樹, 木村隆仁, 長井良憲, 高津聖志, 藤本ゆかり, 深瀬浩一
- Organizer
  日本化学会秋季事業第3回CSJ化学フェスタ2013
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] 副腎白質ジストロフィー: レンチウイルスベクターを用いたABCD1遺伝子発現と骨髄移植2013
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  平成25年度日本薬学会北陸支部第125回例会
- Place of Presentation
  北陸大学薬学部アネックスファーム（石川）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] β3-adrenergic receptor-mediated lipolysis of adipocytes induces accumulation of large number of neutrophils and pro-inflammatory responses in mouse adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] β3-adrenergic receptor-mediated lipolysis of adipocytes induces accumulation of large number of neutrophils and pro-inflammatory responses in mouse adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] Isoliquiritigenin and glycyrrhizin inhibit the inflammasome activation in a different manner2013
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  The 100th Annual Meeting of The American Association of Immunologists(第100回アメリカ免疫学会)
- Place of Presentation
  Hawaii Convention Center（アメリカ合衆国）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] β3-adrenergic receptor-mediated lipolysis of adipocytes induces accumulation of large number of neutrophils and pro-inflammatory responses in mouse adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] 自然免疫受容体TLR4/MD-2複合体の新規リガンド創製を目指したイソプレノイド脂質の構造解析と合成研究2013
- Author(s)
  溝手啓介, 佐伯昭典, 本田裕恵, 岡本直樹, 木村隆仁, 長井良憲, 高津聖志, 藤本ゆかり, 深瀬浩一
- Organizer
  日本化学会秋季事業第3回CSJ化学フェスタ2013
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] 甘草成分はTLR4及びNLRP3インフラマソーム活性化を阻害する2013
- Author(s)
  本田裕恵, 長井良憲, 高村（赤司）祥子, 齋藤伸一郎, 三宅健介, 高津聖志
- Organizer
  第19回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  ロイヤルオークホテルスパ＆ガーデンズ（滋賀）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] 副腎白質ジストロフィー: レンチウイルスベクターを用いたABCD1遺伝子発現と骨髄移植2013
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  平成25年度日本薬学会北陸支部第125回例会
- Place of Presentation
  北陸大学薬学部アネックスファーム（石川）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] メタボリック症候群における慢性炎症を制御する自然免疫シグナルの解析2013
- Author(s)
  長井良憲, 渡邉康春, 本田裕恵, 戸邉一之, 高津聖志
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] Regulatory mechanisms of Radioprotective 105/MD-1 expression in inflammatory macrophages in the adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第78回日本インターフェロン・サイトカイン学会, 第21回マクロファージ分子細胞生物学国際シンポジウム合同学術集会
- Place of Presentation
  都市センターホテル（東京）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] Isoliquiritigenin and glycyrrhizin inhibit the inflammasome activation in a different manner2013
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  The 100th Annual Meeting of The American Association of Immunologists(第100回アメリカ免疫学会)
- Place of Presentation
  Hawaii Convention Center（アメリカ合衆国）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] The roles of IL-5 producing ILC2 in the intestinal immunity2013
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] β3-adrenergic receptor-mediated lipolysis of adipocytes induces accumulation of large number of neutrophils and pro-inflammatory responses in mouse adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] Isoliquiritigenin and glycyrrhizin inhibit the inflammasome activation in a different manner2013
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  The 100th Annual Meeting of The American Association of Immunologists(第100回アメリカ免疫学会)
- Place of Presentation
  Hawaii Convention Center（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] The roles of IL-5 producing ILC2 in the intestinal immunity2013
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] Regulatory mechanisms of Radioprotective 105/MD-1 expression in inflammatory macrophages in the adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第78回日本インターフェロン・サイトカイン学会, 第21回マクロファージ分子細胞生物学国際シンポジウム合同学術集会
- Place of Presentation
  都市センターホテル（東京）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] The roles of IL-5 producing ILC2 in the intestinal immunity2013
- Author(s)
  Tsutomu Yanagibashi, Masashi Ikutani, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] メタボリック症候群における慢性炎症を制御する自然免疫シグナルの解析2013
- Author(s)
  長井良憲, 渡邉康春, 本田裕恵, 戸邉一之, 高津聖志
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 腸管免疫におけるIL-5産生ILC2の役割の解明2013
- Author(s)
  生谷尚士, 柳橋努, 長井良憲, 高津聖志
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] 自然免疫受容体TLR4/MD-2複合体の新規リガンド創製を目指したイソプレノイド脂質の構造解析と合成研究2013
- Author(s)
  溝手啓介, 佐伯昭典, 本田裕恵, 岡本直樹, 木村隆仁, 長井良憲, 高津聖志, 藤本ゆかり, 深瀬浩一
- Organizer
  日本化学会秋季事業第3回CSJ化学フェスタ2013
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] 腸管免疫におけるIL-5産生ILC2の役割の解明2013
- Author(s)
  生谷尚士, 柳橋努, 長井良憲, 高津聖志
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  国立京都国際会館（京都）
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] Regulatory mechanisms of Radioprotective 105/MD-1 expression in inflammatory macrophages in the adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第78回日本インターフェロン・サイトカイン学会, 第21回マクロファージ分子細胞生物学国際シンポジウム合同学術集会
- Place of Presentation
  都市センターホテル（東京）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Regulatory mechanisms of Radioprotective 105/MD-1 expression in inflammatory macrophages in the adipose tissue2013
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第78回日本インターフェロン・サイトカイン学会, 第21回マクロファージ分子細胞生物学国際シンポジウム合同学術集会
- Place of Presentation
  都市センターホテル（東京）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] 副腎白質ジストロフィー: レンチウイルスベクターを用いたABCD1遺伝子発現と骨髄移植2013
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  平成25年度日本薬学会北陸支部第125回例会
- Place of Presentation
  北陸大学薬学部アネックスファーム（石川）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] メタボリック症候群における慢性炎症を制御する自然免疫シグナルの解析2013
- Author(s)
  長井良憲, 渡邉康春, 本田裕恵, 戸邉一之, 高津聖志
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] 甘草成分はTLR4及びNLRP3インフラマソーム活性化を阻害する2013
- Author(s)
  本田裕恵, 長井良憲, 高村（赤司）祥子, 齋藤伸一郎, 三宅健介, 高津聖志
- Organizer
  第19回日本エンドトキシン・自然免疫研究会
- Place of Presentation
  ロイヤルオークホテルスパ＆ガーデンズ（滋賀）
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] メタボリック症候群における慢性炎症を制御する自然免疫シグナルの解析2013
- Author(s)
  長井良憲, 渡邉康春, 本田裕恵, 戸邉一之, 高津聖志
- Organizer
  第34回日本肥満学会
- Place of Presentation
  東京国際フォーラム（東京）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] TLRファミリー分子RP105/MD-1は高脂肪食誘発性の肥満、脂肪組織炎症、インスリン抵抗性を制御する2012
- Author(s)
  長井良憲
- Organizer
  第33回日本炎症・再生医学会
- Place of Presentation
  ホテル日航福岡（福岡県）
- Year and Date
  2012-07-05
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] Potential roles for soluble MD-1 in disease progression of autoimmune prone MRLlpr/lpr mice2012
- Author(s)
  Yoshinori Nagai
- Organizer
  The 99th Annual Meeting of The American Association of Immunologists（第99回アメリカ免疫学会）
- Place of Presentation
  Hynes Convention Center（アメリカ合衆国）
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Regulation of adipose tissue inflammation by TLR family protein RP105/MD-12012
- Author(s)
  Yoshinori Nagai
- Organizer
  The 12th Biennial International Endotoxin Innate Immunity Society Meeting
- Place of Presentation
  学術総合センター（東京都）
- Year and Date
  2012-10-23
- Invited
- Data Source
  KAKENHI-PUBLICLY-24117708
[Presentation] EMPs behave as the bioactive carrier in inflammatory condition2011
- Author(s)
  Yamamoto S, Azuma E, Muramatsu M, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Matsuda N, Niida S, Hattori Y
- Organizer
  The Second Pacific Symposium on Vascular Biology
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 脳血管内皮細胞由来EMPのin vitro産生系の確立と疾患biomarkerおよびbioactive carrierとしての検討2011
- Author(s)
  山本誠士, 東英梨月, 村松昌, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 新飯田俊平, 服部裕一
- Organizer
  第52回日本脈管学会総会
- Place of Presentation
  岐阜
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] Endothelial microparticles (EMP)の生物活性の解析2011
- Author(s)
  山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
- Organizer
  第21回日本循環薬理学会
- Place of Presentation
  岡山
- Year and Date
  2011-12-02
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] The RP105/MD-1 complex plays critical roles in diet-induced obesity and adipose tissue inflammation independent of palmitate-TLR4 signaling2011
- Author(s)
  長井良憲
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉市)
- Year and Date
  2011-11-28
- Data Source
  KAKENHI-PROJECT-23659247
[Presentation] EMPのbioactive carrierという側面からの解析2011
- Author(s)
  山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
- Organizer
  第62回日本薬理学会北部会
- Place of Presentation
  仙台
- Year and Date
  2011-09-29
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] Endothelial microparticlesの疾患バイオマーカーとしての可能性の検討2011
- Author(s)
  山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
- Organizer
  第32回日本循環制御学会総会
- Place of Presentation
  富山
- Year and Date
  2011-06-10
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 天然物によるTh1依存性交叉提示増強の探索 Various phorbol esters promote Th1-dependent antigen cross-presentation by APCs.2011
- Author(s)
  Kariyone A.、 Ikutani M.、 Nagai Y. and Takatsu K.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-23659247
[Presentation] The major IL-5-producing cells in the intestine and lung are c-kit+ CD3ε- cells.2011
- Author(s)
  Yanagibashi T.、 Ikutani M.、 Kouro T.、 Itakura A.、 Nagai Y.、 Takaki S. and Takatsu K.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-23659247
[Presentation] Endothelial microparticles (EMP)のin vitro産生系の確立と炎症biomarkerおよびbioactive carrierとしての検討2011
- Author(s)
  山本誠士, 東英梨月, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 宮崎賢治, 堂本光子, 村松昌, 新飯田俊平, 服部裕一
- Organizer
  第53回日本平滑筋学会総会
- Place of Presentation
  東京
- Year and Date
  2011-08-03
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] The RP105/MD-1 complex plays critical roles in diet-induced obesity and adipose tissue inflammation independent of palmitate-TLR4 signaling2011
- Author(s)
  長井良憲
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉市)
- Year and Date
  2011-11-29
- Data Source
  KAKENHI-PUBLICLY-22117509
[Presentation] Elucidation of the nature of the endothelial microparticles2011
- Author(s)
  Yamamoto S, Azuma E, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Muramatsu M, Niida S, Hattori Y
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] メタボリック症候群における自然免疫制御機構2011
- Author(s)
  長井良憲
- Organizer
  第32回富山大学和漢医薬学総合研究所特別セミナー
- Place of Presentation
  富山県民会館(富山市)(招待講演)
- Year and Date
  2011-12-10
- Data Source
  KAKENHI-PUBLICLY-22117509
[Presentation] The RP105/MD-1 complex plays critical roles in diet-induced obesity and adipose tissue inflammation independent of palmitate-TLR4 signaling.2011
- Author(s)
  Nagai Y.、 Watanabe Y.、 Nakamura T.、 Ikutani M.、 Kariyone A.、 Akira S.、 Miyake K. and Takatsu K.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-23659247
[Presentation] 甘草及びその成分はTLR4を介した免疫応答を直接制御する Glycyrrhizae Radix and its components directly regulate TLR4-mediated immune responses.2011
- Author(s)
  Honda H.、 Nagai Y.、 Miyake K. and Takatsu K.
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-23659247
[Presentation] 抗肥満・抗糖尿病薬シーズ探索のための新評価系・モデルマウスの開発2011
- Author(s)
  長井良憲
- Organizer
  第10回国際バイオEXPOバイオアカデミックフォーラム
- Place of Presentation
  東京ビックサイト(東京都)
- Year and Date
  2011-07-01
- Data Source
  KAKENHI-PUBLICLY-22117509
[Presentation] Endothelial microparticles behave as a bioactive carrier in the cellular interaction2011
- Author(s)
  Yamamoto S, Azuma E, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Muramatsu M, Niida S, Hattori Y
- Organizer
  The 19th Annual Meeting of the Japanese Vascular Biology and Medicine Organization/The 1st Asia-Pacific Vascular Biology Meeting
- Place of Presentation
  Tokyo, Japan
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] EMPs behave as the bioactive carrier in inflammatory condition. The Second Pacific Symposium on Vascular Biology2011
- Author(s)
  Yamamoto S, Azuma E, Muramatsu M, Yanagibashi T, Ikutani M, Nagai Y, Takatsu K, Miyazaki K, Dohmoto M, Matsuda N, Niida S, Hattori Y
- Organizer
  The Second Pacific Symposium on Vascular Biology
- Place of Presentation
  Jeju, Korea
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 自然炎症:免疫制御との接点2011
- Author(s)
  高津聖志、長井良憲
- Organizer
  第12回Pharmaco-Hematologyシンポジウム
- Place of Presentation
  富山国際会議場(富山市)(招待講演)
- Year and Date
  2011-06-18
- Data Source
  KAKENHI-PROJECT-21790463
[Presentation] NG2 positive cerebral microvascular pericytes are potentially derived from circulating myeloid progenitors.2010
- Author(s)
  Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Koo BN, Mukouyama Y, Osawa T, Takahashi H, Takano KI, Watanabe Y, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
- Organizer
  The 16th International Vascular Biology Meeting
- Place of Presentation
  UCLA, Los Angeles, California
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] マウス脳血管内皮細胞株を用いたEndothelial microparticles(EMP)のin vitro産生系の確立および疾患バイオマーカーとしての可能性の検討2010
- Author(s)
  山本誠士, 東英梨月, 村松昌, 宮崎賢治, 佐竹美芽, 堂本光子, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 新飯田俊平, 服部裕一
- Organizer
  第33回日本分子生物学会(BMB2010)
- Place of Presentation
  神戸
- Year and Date
  2010-12-10
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] Cerebrovascular pericytes are potentially derived from the circulating myeloid progenitors2010
- Author(s)
  Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Osawa T, Takahashi H, Takano KI, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
- Organizer
  Keystone Symposia, Angiogenesis in Health and Disease
- Place of Presentation
  Keystone, Colorado
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 自然免疫システムによる慢性炎症の制御2010
- Author(s)
  長井良憲, ら
- Organizer
  第1回富山・バーゼル医薬品研究開発シンポジウム
- Place of Presentation
  富山
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PUBLICLY-22117509
[Presentation] Cerebrovascular pericytes are potentially derived from the circulating myeloid progenitors.2010
- Author(s)
  Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Osawa T, Takahashi H, Takano KI, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
- Organizer
  Keystone Symposia, Angiogenesis in Health and Disease
- Place of Presentation
  Keystone, Colorado
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 血管内皮細胞株を用いたEndothelial microparticles(EMP)の効率的な産生系の確立および疾患バイオマーカーとしての可能性の検討2010
- Author(s)
  山本誠士, 東英梨月, 村松昌, 宮崎賢治, 佐竹美芽, 堂本光子, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 新飯田俊平, 服部裕一
- Organizer
  第20回日本循環薬理学会
- Place of Presentation
  札幌
- Year and Date
  2010-11-11
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 脳血管内皮細胞株を用いたendothelial microparticles(EMP)のin vitro産生系の確立およびin vivo病態モデルでの解析2010
- Author(s)
  山本誠士, 東英梨月, 村松昌, 柳橋努, 生谷尚士, 長井良憲, 高津聖志, 渡邉淳, 堂本光子, 新飯田俊平, 服部裕一
- Organizer
  第18回日本血管生物医学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] NG2 positive cerebral microvascular pericytes are potentially derived from circulating myeloid progenitors2010
- Author(s)
  Yamamoto S, Muramatsu M, Azuma E, Dohmoto M, Koo BN, Mukouyama Y, Osawa T, Takahashi H, Takano KI, Watanabe Y, Ikutani M, Nagai Y, Takatsu K, Usui I, Tobe K, Niida S, Shibuya M, Matsuda N, Hattori Y
- Organizer
  The 16th International Vascular Biology Meeting
- Place of Presentation
  UCLA, Los Angeles, California
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] The RP105/MD-1 complex is required for TLR4/MD-2-degendent plasma cell differentiation and robust IgM production in marginal zone B cells2010
- Author(s)
  Nagai, Y., et al.
- Organizer
  The 14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Year and Date
  2010-08-22
- Data Source
  KAKENHI-PUBLICLY-22117509
[Presentation] TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells2009
- Author(s)
  Nagai, Y
- Organizer
  The 9th World Congress on Inflammation
- Place of Presentation
  東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-21790463
[Presentation] ペリサイト前駆細胞は中枢神経発生期に脳微小血管ヘリクルートされる2009
- Author(s)
  山本誠士, 村松昌, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
- Organizer
  第51回日本平滑筋学会総会
- Place of Presentation
  名古屋
- Year and Date
  2009-07-22
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] 中枢神経発生期におけるペリサイト前駆細胞の脳微小血管網へのリクルートメント2009
- Author(s)
  山本誠士, 村松昌, 大澤毅, 高橋宏行, 東英梨月, 堂本光子, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
- Organizer
  第19回日本循環薬理学会
- Place of Presentation
  京都
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] TLR4/MD-2 and RP 105/MD-1 differentially regulate LPS responsiveness in B cells.2009
- Author(s)
  Nagai, Y., et al.
- Organizer
  The 96^<th> Annual Meeting of The American Association of Immunologists
- Place of Presentation
  Seattle, Washington
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21790463
[Presentation] Macrophage形成不全マウスおよびtime lapse imagingを用いたペリサイト前駆細胞の発生学的検討2009
- Author(s)
  山本誠士, 村松昌, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
- Organizer
  第17回日本血管生物医学会
- Place of Presentation
  東京
- Year and Date
  2009-10-09
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] TLR4/MD-2 and RP 105/MD-1 differentially regulate LPS responsiveness in B cells.2009
- Author(s)
  Nagai, Y., et al.
- Organizer
  The 9^<th> World Congress on Inflammation
- Place of Presentation
  東京
- Year and Date
  2009-07-08
- Data Source
  KAKENHI-PROJECT-21790463
[Presentation] Myeloid系細胞形成不全マウスを用いたペリサイト前駆細胞の発生学的検討および発現遺伝子解析2009
- Author(s)
  山本誠士?, 村松昌, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之、服部裕一
- Organizer
  第60回日本薬理学会北部会
- Place of Presentation
  富山
- Year and Date
  2009-09-26
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells2009
- Author(s)
  Nagai, Y
- Organizer
  The 96th Annual Meeting of The American Association of Immunologists
- Place of Presentation
  Seattle, Washington
- Year and Date
  2009-05-11
- Data Source
  KAKENHI-PROJECT-21790463
[Presentation] 脳微小血管網を構成するペリサイトは造血系細胞由来である2009
- Author(s)
  山本誠士, 村松昌, Bon-nyeo Koo, 向山洋介, 喜多紗斗美, 岩本隆宏, 東英梨月, 堂本光子, 渡邊泰秀, 小室一成, 大澤毅, 高橋宏行, 高野健一, 生谷尚士, 長井良憲, 高津聖志, 薄井勲, 戸邉一之, 新飯田俊平, 澁谷正史, 松田直之, 服部裕一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-21590589
[Presentation] Identification of soluble MD-1 and its role in autoimmune diseases2008
- Author(s)
  Sasaki, S., Y. Nagai and K. Takatsu.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-19790354
[Presentation] TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells2008
- Author(s)
  Nagai, Y., et al.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20390141
[Presentation] TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells2008
- Author(s)
  Nagai, Y., M. Ikutani, A. Kariyone, S. Ohta, K. Miyake and K. Takatsu
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19790354
[Presentation] TLR4/MD-2 and RP105/MD-1 differentially regulate LPS responsiveness in B cells.2008
- Author(s)
  Nagai, Y.
- Organizer
  第38回日本免疫学会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-20390141
[Presentation] PDCA-1 and mouse plasmacytoid DC precursor cells2008
- Author(s)
  Nakamura, T., Y. Nagai and K. Takatsu.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19790354
[Presentation] Natural plant products modulate innate immunity via TLRs2008
- Author(s)
  Honda, H., Y. Nagai, K. Miyake and K. Takatsu.
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19790354
[Presentation] B-1 cell-restricted differentiation of IL-7R+ lymphoid progenitors from fetal liver2008
- Author(s)
  Kouro, T., M. Ikutani, A. Teratani, Y. Nagai and K. Takatsu
- Organizer
  第38回日本免疫学会総会・学術集会
- Place of Presentation
  京都
- Year and Date
  2008-12-02
- Data Source
  KAKENHI-PROJECT-19790354
[Presentation] Microbial flora-independent signaling via Toll-like receptor 2/4 and RP105 induces IgG3 and predisposes to lupus nephritis2007
- Author(s)
  Kobayashi, T., K. Takahashi, Y. Nagai, T. Shibata, Y. Gotoh, H. Kiyono, S. Akira and K. Miyake.
- Organizer
  第37回日本免疫学会総会・学術集会
- Place of Presentation
  東京
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790354
[Presentation] Hematopoietic stem/progenitor cells express functional Toll-like receptors that potentially stimulate replenishment of the innate immune system.2006
- Author(s)
  Nagai, Y.
- Organizer
  The American Association of Immunologists Annual Meeting
- Place of Presentation
  Boston, MA
- Year and Date
  2006-05-15
- Data Source
  KAKENHI-PROJECT-16109004
[Presentation] Toll-like receptors on hematopoietic ptogenitor cells stimulate innate immune system replenishment.2006
- Author(s)
  Nagai, Y.
- Organizer
  Joint Meeting of the Society for Leukocyte Biology and the International Endotoxin and Innate Immunity Society
- Place of Presentation
  San Antonio, TX
- Year and Date
  2006-11-10
- Data Source
  KAKENHI-PROJECT-16109004
[Presentation] Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment2006
- Author(s)
  Nagai Y, Garrett KP, Ohta S, Bahrun U, Kouro T, Akira S, Takatsu K, Kincade PW
- Organizer
  第36回日本免疫学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-16109004
[Presentation] Toll-like receptors on hematopoietic progenitor cells stimulate innate immune system replenishment2006
- Author(s)
  Nagai Y, Garrett KP, Ohta S, Bahrun U, Kouro T, Akira S, Takastu K, Kincade PW
- Organizer
  A Joint Meeting of the Society of Leukocyte Biology and the International Endotoxin and Innate Immunity Society
- Place of Presentation
  San Antonio, TX
- Data Source
  KAKENHI-PROJECT-16109004
[Presentation] 遊離脂肪酸誘発性の内臓脂肪組織炎症における好中球とIL-1シグナルの機能解析
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Organizer
  第35回日本肥満学会
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター（宮崎）
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] Structural determination and synthesis of isoprenoids as immune activators via TLR4/MD-2
- Author(s)
  Mizote Keisuke, Saeki Akinori, Honda Hiroe, Okamoto Naoki, Kimura Takahito, Nagai Yoshinori, Takatsu Kiyoshi, Fujimoto Yukari, Fukase Koichi
- Organizer
  2014 SLB IEIIS Meeting
- Place of Presentation
  Salt Lake City Sheraton（アメリカ合衆国）
- Year and Date
  2014-10-23 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] モデルマウスを用いた副腎白質ジストロフィーに対する骨髄移植の検討
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  日本薬学会第13回次世代を担う若手ファーマ・バイオフォーラム2014
- Place of Presentation
  富山国際会議場（富山）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation.
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] Adipocyte-derived free fatty acids trigger IL-1β production by neutrophils in mouse adipose tissue
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] An antibiotics funiculosin derivative is a novel agonist of Toll-like receptor 4
- Author(s)
  Naoki Okamoto, Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 遊離脂肪酸誘発性の内臓脂肪組織炎症における好中球とIL-1シグナルの機能解析
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Organizer
  第35回日本肥満学会
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター（宮崎）
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] モデルマウスを用いた副腎白質ジストロフィーに対する骨髄移植の検討マウスを用いた副腎白質ジストロフィーに対する骨髄移植の検討
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  日本薬学会第13回次世代を担う若手ファーマ・バイオフォーラム2014
- Place of Presentation
  富山国際会議場（富山）
- Year and Date
  2014-09-20 – 2014-09-21
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] An antibiotics funiculosin derivative is a novel agonist of Toll-like receptor 4
- Author(s)
  Naoki Okamoto, Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] 遊離脂肪酸誘発性の内臓脂肪組織炎症における好中球とIL-1シグナルの機能解析脂肪酸誘発性の内臓脂肪組織炎症における好中球とIL-1シグナルの機能解析
- Author(s)
  長井良憲, 渡邉康春, 高津聖志
- Organizer
  第35回日本肥満学会
- Place of Presentation
  フェニックスシーガイアリゾートコンベンションセンター（宮崎）
- Year and Date
  2014-10-24 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] 副腎白質ジストロフィー：レンチウイルスベクターによるABCD1タンパク質の発現と骨髄移植
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  第56回日本先天代謝異常学会総会
- Place of Presentation
  江陽グランドホテル（仙台）
- Year and Date
  2014-11-13 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Roles of IL-5-producing ILC2 in vascular pathogenesis
- Author(s)
  Ikutani Masashi, Tsuneyama Koichi, Nagai Yoshinori, Takatsu Kiyoshi
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] IL-33に誘導される血管壁肥厚とIL-5産生ILC2
- Author(s)
  生谷尚士, 常山幸一, 長井良憲, 高津聖志
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館（沖縄）
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] IL-33に誘導される血管壁肥厚とIL-5産生ILC2
- Author(s)
  生谷尚士, 常山幸一, 長井良憲, 高津聖志
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館（沖縄）
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Roles of IL-5-producing ILC2 in vascular pathogenesis
- Author(s)
  Masashi Ikutani, Koichi Tsuneyama, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Adipocyte-derived free fatty acids trigger IL-1β production by neutrophils in mouse adipose tissue
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Isoliquiritigenin is a potent inhibitor of NLRP3 inflammasome activation and diet-induced adipose tissue inflammation
- Author(s)
  Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] Structural determination and synthesis of isoprenoids as immune activators via TLR4/MD-2
- Author(s)
  Mizote Keisuke, Saeki Akinori, Honda Hiroe, Okamoto Naoki, Kimura Takahito, Nagai Yoshinori, Takatsu Kiyoshi, Fujimoto Yukari, Fukase Koichi
- Organizer
  2014 SLB IEIIS Meeting
- Place of Presentation
  Salt Lake City Sheraton（アメリカ合衆国）
- Year and Date
  2014-10-23 – 2014-10-25
- Data Source
  KAKENHI-PROJECT-24590577
[Presentation] 副腎白質ジストロフィー：レンチウイルスベクターによるABCD1タンパク質の発現と骨髄移植
- Author(s)
  松本隼, 守田雅志, 渡邉康春, 長井良憲, 小林博司, 高津聖志, 今中常雄
- Organizer
  第56回日本先天代謝異常学会総会
- Place of Presentation
  江陽グランドホテル（仙台）
- Year and Date
  2014-11-13 – 2014-11-15
- Data Source
  KAKENHI-PROJECT-24390119
[Presentation] Adipocyte-derived free fatty acids trigger IL-1β production by neutrophils in mouse adipose tissue.
- Author(s)
  Yasuharu Watanabe, Yoshinori Nagai, Koichi Tsuneyama, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25126707
[Presentation] An antibiotics funiculosin derivative is a novel agonist of Toll-like receptor 4.
- Author(s)
  Naoki Okamoto, Hiroe Honda, Yoshinori Nagai, Kiyoshi Takatsu
- Organizer
  第43回日本免疫学会学術集会
- Place of Presentation
  国立京都国際会館（京都）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PUBLICLY-25126707

1. TAKATSU Kiyoshi (10107055)

# of Collaborated Projects: 5 results

# of Collaborated Products: 43 results
2. OGASAWARA MASARU (30443427)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
3. KARIYONE Ai (50114450)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. IKUTANI Masashi (40513718)

# of Collaborated Projects: 3 results

# of Collaborated Products: 10 results
5. TAMURA Toshiki (40291306)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. HONDA Hiroe (10463134)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
7. WATANABE Yasuharu (80646307)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
8. TAKAKI Satoshi (10242116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. KOURO Taku (90372424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. YAMAMOTO Seiji (10456361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
11. HATTORI Yuichi (50156361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
12. MATSUNAGA Takayuki (30121289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. MIYAMOTO Tomomi (20443426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. YAMASAKI Shimno (50602182)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. MORITA MASASHI (20191033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
16. 多喜博文 (10240780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 篠田晃一郎 (40377312)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 常山幸一 (10293341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
19. USUI Isao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. GODA Nobuhito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 柳橋努

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 小川佳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 佐田政隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 渡邊善之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 古家大祐

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 喜多紗斗美

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 笹原正清

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nagai Yoshinori 長井 良憲

NAGAI Yoshinori 長井 良憲

Research Projects

Research Products

Co-Researchers

肝臓マクロファージサブセット解析から迫る新規線維化亢進NASHマウスの病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel autoimmune therapeutics that selectively inhibit TLR7 activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of the innate immune signal that induces hypothalamic inflammation and feeding dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

自然免疫シグナル分子による摂食反応・肥満制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脂肪組織炎症を制御するＲＰ１０５／ＭＤ－１の機能解析及び内因性リガンドの探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for innate immune molecules and compounds that regulate adipose tissue inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

脂肪組織の自然炎症におけるRP105/MD-1シグナルと可溶型MD-1の機能解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Nagai Yoshinori 長井良憲

NAGAI Yoshinori 長井良憲

[Book] 第4章 13節 RP105. 「seriesモデル動物利用マニュアル　疾患モデルの作製と利用ー脂質代謝異常と関連疾患<下巻>」. 尾池雄一, 佐々木雄彦, 村上誠, 矢作直也編集.2015