Harusato Akihito 春里暁人

Researcher Number	30434509
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 特任講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 京都府立医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 49030:Experimental pathology-related / Gastroenterology
Keywords	Principal Investigator IL-36 / サイトカイン / 腸内細菌 / マイクロプラスチック / 食物アレルギー / 抗原提示細胞 / 腸炎 / 腸管 / 食品乳化剤 / ナノ/マイクロプラスチック … More / 腸管樹状細胞 / 腸管バリア / 炎症性腸疾患 / Erdr-1 / MDSC / 大腸 / ２型サイトカイン / 2型サイトカイン / 大腸がん / 大腸癌 / 免疫 / 腸管免疫 / 腸管炎症 Less

Intestinal homeostasis and the mechanism of food allergyPrincipal Investigator
- Principal Investigator
  
  春里暁人
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kyoto Prefectural University of Medicine
Antigen presenting cell mediated regulation of intestinal inflammationPrincipal Investigator
- Principal Investigator
  
  Harusato Akihito
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Kyoto Prefectural University of Medicine
IL-36 mediated regulation of intestinal inflammationPrincipal Investigator
- Principal Investigator
  
  春里暁人
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto Prefectural University of Medicine

All 2024 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota.2023
- Author(s)
  Abo H, Muraki A, Harusato A, Imura T, Suzuki M, Takahashi K, Denning TL, Kawashima H.
- Journal Title
  
  JCI Insight
  
  Volume: 8 Issue: 16 Pages: 165944-165944
- DOI
  10.1172/jci.insight.165944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K18173, KAKENHI-PROJECT-22K11731, KAKENHI-PROJECT-23K14342
[Journal Article] Protocol for acquiring samples to assess the impact of microplastics on immune microenvironments in the mouse intestine2023
- Author(s)
  Harusato Akihito、Seo Wooseok、Abo Hirohito、Nakanishi Yoshitaka、Nishikawa Hiroyoshi、Itoh Yoshito
- Journal Title
  
  STAR Protocols
  
  Volume: 4 Issue: 4 Pages: 102648-102648
- DOI
  10.1016/j.xpro.2023.102648
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0096, KAKENHI-PROJECT-22K11731, KAKENHI-PROJECT-22H00455
[Journal Article] Impact of particulate microplastics generated from polyethylene terephthalate on gut pathology and immune microenvironments2023
- Author(s)
  Harusato Akihito、Seo Wooseok、Abo Hirohito、Nakanishi Yoshitaka、Nishikawa Hiroyoshi、Itoh Yoshito
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 4 Pages: 106474-106474
- DOI
  10.1016/j.isci.2023.106474
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11731, KAKENHI-PROJECT-18K15128, KAKENHI-PROJECT-19KK0096, KAKENHI-PROJECT-22H00455
[Journal Article] Dietary Emulsifiers Exacerbate Food Allergy and Colonic Type 2 Immune Response through Microbiota Modulation2022
- Author(s)
  Harusato Akihito、Chassaing Benoit、Dauriat Charl?ne J. G.、Ushiroda Chihiro、Seo Wooseok、Itoh Yoshito
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 23 Pages: 4983-4983
- DOI
  10.3390/nu14234983
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11731, KAKENHI-PROJECT-20K19672, KAKENHI-PROJECT-18K15128
[Journal Article] 腸管免疫細胞のクロストーク2021
- Author(s)
  春里暁人、伊藤義人
- Journal Title
  
  京府医大誌.
  
  Volume: 130 (4) Pages: 287-295
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15128
[Journal Article] Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration2020
- Author(s)
  Abo Hirohito、Chassaing Benoit、Harusato Akihito、Quiros Miguel、Brazil Jennifer C.、Ngo Vu L.、Viennois Emilie、Merlin Didier、Gewirtz Andrew T.、Nusrat Asma、Denning Timothy L.
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 513-513
- DOI
  10.1038/s41467-019-14258-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15128
[Journal Article] Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3+ Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis2019
- Author(s)
  Abo Hirohito、Flannigan Kyle L.、Geem Duke、Ngo Vu L.、Harusato Akihito、Denning Timothy L.
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10
- DOI
  10.3389/fimmu.2019.00459
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15128
[Journal Article] Early-Life Microbiota Exposure Restricts Myeloid-Derived Suppressor Cell Driven Colonic Tumorigenesis2019
- Author(s)
  Harusato Akihito、Viennois Emilie、Etienne-Mesmin Lucie、Matsuyama Shingo、Abo Hirohito、Osuka Satoru、Lukacs Nicholas W.、Naito Yuji、Itoh Yoshito、Li Jian-Dong、Merlin Didier、Gewirtz Andrew T.、Denning Timothy L.
- Journal Title
  
  Cancer Immunology Research
  
  Volume: 7 Issue: 4 Pages: 544-551
- DOI
  10.1158/2326-6066.cir-18-0444
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15128
[Journal Article] A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage2018
- Author(s)
  Ngo Vu L.、Abo Hirohito、Maxim Estera、Harusato Akihito、Geem Duke、Medina-Contreras Oscar、Merlin Didier、Gewirtz Andrew T.、Nusrat Asma、Denning Timothy L.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 22
- DOI
  10.1073/pnas.1718902115
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15128
[Journal Article] Heme oxygenase-1 prevents murine intestinal inflammation2018
- Author(s)
  Takagi Tomohisa、Naito Yuji、Mizushima Katsura、Hirai Yasuko、Harusato Akihito、Okayama Tetsuya、Katada Kazhuhiro、Kamada Kazuhiro、Uchiyama Kazuhiko、Handa Osamu、Ishikawa Takeshi、Itoh Yoshito
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 63 Issue: 3 Pages: 169-174
- DOI
  10.3164/jcbn.17-133
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15128, KAKENHI-PROJECT-16K09322
[Journal Article] IL-36γ signaling controls the induced regulatory T cell-Th9 cell balance via NFkB activation and STAT transcription factors2017
- Author(s)
  Harusato A、Abo H、Ngo V L、Yi S W、Mitsutake K、Osuka S、Kohlmeier J E、Li J D、Gewirtz A T、Nusrat A、Denning T L
- Journal Title
  
  Mucosal Immunology
  
  Volume: 10 Issue: 6 Pages: 1455-1467
- DOI
  10.1038/mi.2017.21
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07013
[Journal Article] Insights on the impact of diet-mediated microbiota alterations on immunity and diseases2017
- Author(s)
  Harusato Akihito、Chassaing Benoit
- Journal Title
  
  American Journal of Transplantation
  
  Volume: 18 Issue: 3 Pages: 550-555
- DOI
  10.1111/ajt.14477
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07013
[Presentation] Impact of PET-derived microplastics on gut immune microenvironments2024
- Author(s)
  Akihito Harusato, Wooseok Seo, Hirohito Abo, Yoshitaka Nakanishi, Hiroyoshi Nishikawa, Yoshito Itoh
- Organizer
  第52回日本免疫学会学術総会
- Data Source
  KAKENHI-PROJECT-22K11731
[Presentation] ポリエチレンテレフタラート由来微細粒子状マイクロプラスチックが腸管免疫微小環境に及ぼす影響2023
- Author(s)
  春里　暁人
- Organizer
  第60回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-22K11731
[Presentation] Do PET microplastics in a real-world environment affect the host and microbiota?2023
- Author(s)
  Akihito Harusato
- Organizer
  Biotribology Fukuoka 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11731
[Presentation] Dietary Emulsifier Polysorbate-80 Exacerbates Experimental Food Allergy and Colonic Type 2 Immune Response Through Microbiota Modulation.2023
- Author(s)
  Akihito Harusato, Benoit Chassaing
- Organizer
  Cell Symposia: Infection biology in the age of microbiome
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K11731
[Presentation] Early life microbiota controls CXCR2 mediated myeloid derived suppressor cell driven colitis-associated tumorigenesis2019
- Author(s)
  Akihito Harusato
- Organizer
  International Congress of Mucosal Immunology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15128
[Presentation] 新生仔期腸内細菌叢が大腸発癌に及ぼす影響に関する検討2019
- Author(s)
  春里暁人
- Organizer
  第57回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-18K15128
[Presentation] Dietary Emulsifier Polysorbate-80 Exacerbates Experimental Food Allergy with Increased Expressions of Colonic Th2 Cytokines2019
- Author(s)
  Akihito Harusato, Benoit Chassaing
- Organizer
  第48回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15128
[Presentation] Interleukin-36γによる腸管バリア維持機構に関する検討2018
- Author(s)
  春里暁人
- Organizer
  第55回日本消化器免疫学会
- Data Source
  KAKENHI-PROJECT-18K15128
[Presentation] Early life microbiota exposure attenuates colonic tumorigenesis2018
- Author(s)
  Akihito Harusato
- Organizer
  Cleveland International Digestive Education and Science Symposium 2018
- Data Source
  KAKENHI-PROJECT-18K15128
[Presentation] IL-36R Signaling in Notch2-Dependent DCs Induces IL-23-Dependent Rsolution of Acute Colonic Damage2017
- Author(s)
  Vu L. Ngo, Hirohito Abo, Akihito Harusato, Asma Nusrat, Timothy Denning and Estera Maxim.
- Organizer
  International Congress of Mucosal Immunology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07013
[Presentation] IL-36 signaling controls the induced regulatory T cell-Th9 Cell balance via NFkB activation and STAT transcription factors2017
- Author(s)
  春里暁人
- Organizer
  International Congress of Mucosal Immunology 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07013
[Presentation] 新規IL-1 family IL-36による腸管免疫制御2017
- Author(s)
  春里暁人
- Organizer
  第181回京都消化器病研究会
- Data Source
  KAKENHI-PROJECT-17H07013
[Presentation] 腸管炎症におけるInterleukin-36の役割2017
- Author(s)
  春里暁人,内藤裕二,高木智久,内山和彦,東村泰希,水島かつら,平井泰子,Vu Ngo,安保博仁 ,岡浩平,石破博,稲田裕,福居顕文,堅田和弘,Tim Denning,伊藤義人
- Organizer
  第54回日本消化器免疫学会
- Data Source
  KAKENHI-PROJECT-17H07013

1. SEO WOOSEOK (40574116)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 川島博人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 中西義孝

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Harusato Akihito 春里 暁人

Research Projects

Research Products

Co-Researchers

Intestinal homeostasis and the mechanism of food allergyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Antigen presenting cell mediated regulation of intestinal inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

IL-36 mediated regulation of intestinal inflammationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] N-acetylglucosamine-6-O-sulfation on intestinal mucins prevents obesity and intestinal inflammation by regulating gut microbiota.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protocol for acquiring samples to assess the impact of microplastics on immune microenvironments in the mouse intestine2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of particulate microplastics generated from polyethylene terephthalate on gut pathology and immune microenvironments2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dietary Emulsifiers Exacerbate Food Allergy and Colonic Type 2 Immune Response through Microbiota Modulation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 腸管免疫細胞のクロストーク2021

Author(s)

Journal Title

Data Source

[Journal Article] Erythroid differentiation regulator-1 induced by microbiota in early life drives intestinal stem cell proliferation and regeneration2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Combined IL-2 Immunocomplex and Anti-IL-5 mAb Treatment Expands Foxp3+ Treg Cells in the Absence of Eosinophilia and Ameliorates Experimental Colitis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Early-Life Microbiota Exposure Restricts Myeloid-Derived Suppressor Cell Driven Colonic Tumorigenesis2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heme oxygenase-1 prevents murine intestinal inflammation2018

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] IL-36γ signaling controls the induced regulatory T cell-Th9 cell balance via NFkB activation and STAT transcription factors2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insights on the impact of diet-mediated microbiota alterations on immunity and diseases2017

Author(s)

Harusato Akihito 春里暁人