Ito Masaaki 伊藤政明

… Alternative Names

ito masaaki 伊藤政明

伊藤政明イトウマサアキ

ITOU Masaaki 伊藤政明

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Researcher Number	30438759
Other IDs
Affiliation (Current)	2025: 高崎健康福祉大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 高崎健康福祉大学, 薬学部, 准教授 2023: 高崎健康福祉大学, 薬学部, 准教授 2019 – 2022: 高崎健康福祉大学, 薬学部, 講師 2015 – 2016: 高崎健康福祉大学, 薬学部, 助教 2009: Takasaki University of Health and Welfare, 薬学部, 助教 2008: Takasaki University of Health and Welfare, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Biological pharmacy Except Principal Investigator Basic Section 48030:Pharmacology-related / Applied health science
Keywords	Principal Investigator マクロファージ / サイトカイン放出症候群 / 気道上皮細胞 / Toll様受容体（TLR）3 / インターフェロン（IFN）-γ / interleukin-6（IL-6） / 機械的刺激 / P2Y6受容体 / MCP-1 / プリン作動性シグナル … More / 機械的進展刺激 / 炎症反応 / 細胞内情報伝達 / プロスタグランジン / プリン受容体 / 細胞外ヌクレオチド … More Except Principal Investigator ATP / IgE / ヒトiPS細胞 / アレルギー疾患 / イオンチャネル / アレルギー反応 / EP3受容体 / プロスタグランジンE2 / P2X4受容体 / 炎症性サイトカイン / 脱顆粒反応 / プリン作動性シグナル / マスト細胞 / 細胞外ATP分解酵素 / P2Y2受容体 / TBC1D1 / Ｒａｂ / Ａｋｔ / ＡＭＰキナーゼ / 細胞外ＡＴＰ分解酵素 / Ｐ２Ｙ２受容体 / ＡＴＰ / グルコース輸送体４ / 糖取り込み / 骨格筋 / 運動トレーニング Less

Analysis of the priming mechanism of IFN-gamma in response to RNA recognition receptor stimulation in airway epithelial cellsPrincipal Investigator
- Principal Investigator
  
  伊藤政明
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Takasaki University of Health and Welfare
Role of purinergic signaling on macrophage function induced by stretch-mediated mechanical stimulation.Principal Investigator
- Principal Investigator
  
  ito masaaki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Takasaki University of Health and Welfare
Establishment of therapeutic basis for allergic diseases targeting P2X4 receptor of mast cells
- Principal Investigator
  
  Matsuoka Isao
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Takasaki University of Health and Welfare
Relationship between enhanced purinergic signalling in skeletal muscle and health promoting effects of exercise training
- Principal Investigator
  
  Matsuoka Isao
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied health science
- Research Institution
  Takasaki University of Health and Welfare
Novel mechanism for regulation of inflammatory response.Principal Investigator
- Principal Investigator
  
  ITOU Masaaki
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Takasaki University of Health and Welfare

All 2024 2023 2022 2021 2020 2019 2017 2016 2015 2010 2009 2008

All Journal Article Presentation Patent

[Journal Article] Enhancement of mast cells activation by ATP via P2X4 receptor2024
- Author(s)
  Kazuki Yoshida , Masa-Aki Ito, Isao Matsuoka
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 159 Issue: 1 Pages: 39-43
- DOI
  10.1254/fpj.23083
- ISSN
  0015-5691, 1347-8397
- Year and Date
  2024-01-01
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06169, KAKENHI-PROJECT-20K16010
[Journal Article] Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A102024
- Author(s)
  Nakamura Yoshinobu、Ito Masa-aki、Hoshino Yukino、Matsuoka Isao、Okada Toshiaki、Okada Yasunobu、Nakanishi Takeo
- Journal Title
  
  American Journal of Physiology-Cell Physiology
  
  Volume: 326 Issue: 4 Pages: C1042-C1053
- DOI
  10.1152/ajpcell.00701.2023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15295, KAKENHI-PROJECT-20K07018, KAKENHI-PROJECT-20K16010
[Journal Article] Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ2023
- Author(s)
  Okuma Norikazu、Ito Masa-aki、Shimizu Tomoyoshi、Hasegawa Atsuya、Ohmori Shin’ya、Yoshida Kazuki、Matsuoka Isao
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 21067-21067
- DOI
  10.1038/s41598-023-48422-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15282, KAKENHI-PROJECT-23K06169, KAKENHI-PROJECT-20K16010
[Journal Article] Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity2022
- Author(s)
  Yamagiwa Noriyuki、Komine Mika、Hanaoka Fumi、Nobuta Tomoya、Yoshida Kazuki、Ito Masaaki、Matsuoka Isao
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 77 Pages: 129035-129035
- DOI
  10.1016/j.bmcl.2022.129035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16010, KAKENHI-PROJECT-22K15282
[Journal Article] Synergistic Cytokine Production by ATP and PGE2 via P2X4 and EP3 Receptors in Mouse Bone-Marrow-Derived Mast Cells2022
- Author(s)
  Obayashi Kosuke、Yoshida Kazuki、Ito Masa-aki、Mori Tetsuya、Yamamoto Kimiko、Imai Toshiyashu、Matsuoka Isao
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 4 Pages: 616-616
- DOI
  10.3390/cells11040616
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07328, KAKENHI-PROJECT-18K14925, KAKENHI-PROJECT-21H03791, KAKENHI-PROJECT-20K16010
[Journal Article] P-Glycoprotein?Mediated Pharmacokinetic Interactions Increase Pimozide hERG Channel Inhibition2022
- Author(s)
  Morishita Hiroki、Perera Liyanage Manosika Buddhini、Zhang Xieyi、Mizoi Kenta、Ito Masa-aki、Yano Kentaro、Ogihara Takuo
- Journal Title
  
  Journal of Pharmaceutical Sciences
  
  Volume: 111 Issue: 12 Pages: 3411-3416
- DOI
  10.1016/j.xphs.2022.09.025
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06782, KAKENHI-PROJECT-20K16010, KAKENHI-PROJECT-21K20729
[Journal Article] P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice2022
- Author(s)
  Yoshida Kazuki、Tanihara Shota、Miyashita Yuki、Obayashi Kosuke、Ito Masa-aki、Yamamoto Kimiko、Imai Toshiyashu、Matsuoka Isao
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 18613-18613
- DOI
  10.1038/s41598-022-21667-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16010, KAKENHI-PROJECT-22K15282, KAKENHI-PROJECT-21H03791
[Journal Article] Differential Effects of Gq Protein-Coupled Uridine Receptor Stimulation on IL-8 Production in 1321N1 Human Astrocytoma Cells2022
- Author(s)
  Ito Masa-aki、Kojima Erika、Yanagihara Yu、Yoshida Kazuki、Matsuoka Isao
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 6 Pages: 691-697
- DOI
  10.1248/bpb.b21-01020
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-06-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16010, KAKENHI-PROJECT-22K15282
[Journal Article] G蛋白質共役型受容体を介するホスホリパーゼCシグナル伝達系の調節機構,2021
- Author(s)
  伊藤政明, 松岡功
- Journal Title
  
  脳神経内科
  
  Volume: 94 Pages: 507-514
- Data Source
  KAKENHI-PROJECT-19K07328
[Journal Article] ATP/P2X4受容体枢軸によるIgE依存性マスト細胞脱顆粒の増強反応2021
- Author(s)
  松岡　功、吉田一貴、伊藤正明
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 75 Pages: 369-376
- NAID
  40022504137
- Data Source
  KAKENHI-PROJECT-19K07328
[Journal Article] マスト細胞のP2X4受容体を介したアレルギー反応の増強2021
- Author(s)
  松岡　功、吉田一貴、伊藤正明
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41 Pages: 176-180
- Data Source
  KAKENHI-PROJECT-19K07328
[Journal Article] ATP/P2X4受容体枢軸によるIgE 依存性マスト細胞脱顆粒の増強反応2021
- Author(s)
  松岡功, 吉田一貴、伊藤政明
- Journal Title
  
  臨床免疫・アレルギー科
  
  Volume: 75 Pages: 369-376
- NAID
  40022504137
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16010
[Journal Article] G蛋白質共役型受容体を介するホスホリパーゼCシグナル伝達系の調節機構2021
- Author(s)
  伊藤政明, 松岡功
- Journal Title
  
  脳神経内科
  
  Volume: 94 Pages: 507-514
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16010
[Journal Article] マスト細胞のP2X4受容体活性化を介したアレルギー反応の増強.2021
- Author(s)
  松岡功, 吉田一貴、伊藤政明
- Journal Title
  
  アレルギーの臨床
  
  Volume: 41 Pages: 171-175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16010
[Journal Article] Gastrointestinal absorption of pimozide is enhanced by inhibition of P-glycoprotein2020
- Author(s)
  Morishita Hiroki、Okawa Kozue、Ishii Misaki、Mizoi Kenta、Ito Masa-aki、Arakawa Hiroshi、Yano Kentaro、Ogihara Takuo
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Issue: 10 Pages: e0232438-e0232438
- DOI
  10.1371/journal.pone.0232438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16010
[Journal Article] Extracellular ATP Augments Antigen-Induced Murine Mast Cell Degranulation and Allergic Responses via P2X4 Receptor Activation2020
- Author(s)
  Yoshida Kazuki、Ito Masa-aki、Sato Naoko、Obayashi Kosuke、Yamamoto Kimiko、Koizumi Schuichi、Tanaka Satoshi、Furuta Kazuyuki、Matsuoka Isao
- Journal Title
  
  The Journal of Immunology
  
  Volume: 204 Issue: 12 Pages: 3077-3085
- DOI
  10.4049/jimmunol.1900954
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07328, KAKENHI-PROJECT-20K07040, KAKENHI-PROJECT-18K14925, KAKENHI-PROJECT-20K16010, KAKENHI-PUBLICLY-19H04746, KAKENHI-PUBLICLY-20H05060, KAKENHI-PROJECT-18H03510, KAKENHI-PROJECT-17K08273, KAKENHI-PROJECT-19K22952, KAKENHI-PROJECT-16H06276
[Journal Article] Co-Stimulation of Purinergic P2X4 and Prostanoid EP3 Receptors Triggers Synergistic Degranulation in Murine Mast Cells2019
- Author(s)
  Yoshida、Tajima、Nagano、Obayashi、Ito、Yamamoto、Matsuoka
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 20 Pages: 5157-5157
- DOI
  10.3390/ijms20205157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07328, KAKENHI-PROJECT-18K14925
[Journal Article] Divergent regulatory roles of extracellular ATP in the degranulation response of mouse bone marrow-derived mast cells2017
- Author(s)
  Yoshida K, Ito M, Matsuoka I
- Journal Title
  
  Int 　Immunopharmacol
  
  Volume: 43 Pages: 99-107
- DOI
  10.1016/j.intimp.2016.12.014
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12707
[Journal Article] P2X7 antagonist activity of the anti-allergic agent oxatomide2015
- Author(s)
  Kazuki Yoshida, Masaaki Ito, Isao Matsuoka
- Journal Title
  
  Europian Journal of Pharmacology
  
  Volume: 767 Pages: 41-51
- DOI
  10.1016/j.ejphar.2015.10.002
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K12707
[Journal Article] Mechanism and role of high density lipoprotein-induced activation of AMP-activated protein kinase in endothelial cells.2010
- Author(s)
  Kimura T, Tomura H, Sato K, Masaaki Ito, Isao Matsuoka, Im DS, Kuwabara A, Mogi C, Itoh H, Kurose H, Murakami M, Okajima F.
- Journal Title
  
  he Journal of Biological Chemistry Vol.285
  
  Pages: 4387-4397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790074
[Journal Article] Mechanism and role of high density hpoprotein-induced activation of AMP-activated protein kinase in endothelial cells.2010
- Author(s)
  Kimura T, Tomura H, Sato K, Masaaki Ito, Isao Matsuoka, et.al.
- Journal Title
  
  The Journal of Biological Chemistry 285
  
  Pages: 4387-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790074
[Journal Article] Gタンパク質共役型受容体を介したホスホリパーゼCシグナル伝達系に対する抑制性調節機構2009
- Author(s)
  松岡功、伊藤政明
- Journal Title
  
  日本薬理学雑誌 134
  
  Pages: 254-258
- NAID
  10025741914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790074
[Journal Article] Gタンパク質共役型受容体を介したホスホリパーゼCシグナル伝達系に対する抑制性調節機構2009
- Author(s)
  松岡功、伊藤政明
- Journal Title
  
  日本薬理学雑誌 Vol.134
  
  Pages: 254-258
- NAID
  10025741914
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790074
[Journal Article] Regulation of Purinergic Signaling by Prostaglandin E2 in Murine Macrophages2008
- Author(s)
  Masaaki Ito, Isao Matsuoka
- Journal Title
  
  Journal of Pharmacological Sciences 107
  
  Pages: 443-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790074
[Journal Article] Regulation of Purinergic Signaling by Prostaglandin E2 in Murine Macrophages.2008
- Author(s)
  Masaaki Ito, Isao Matsuoka
- Journal Title
  
  Journal of Pharmacological Sciences Vol.107
  
  Pages: 443-450
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790074
[Patent] アレルギー反応に伴う症状の予防もしくは抑制または治療用の医薬品組成物2021
- Inventor(s)
  吉田一貴，伊藤政明，松岡功
- Industrial Property Rights Holder
  吉田一貴，伊藤政明，松岡功
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Annexin A2およびS100A10がSLCO2A1のプロスタグランジンE2輸送活性に及ぼす影響2024
- Author(s)
  中村吉伸、伊藤政明、星野雪乃、松岡功、岡田俊昭、岡田泰伸、中西猛夫
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] ヒト培養気管支上皮細胞のpoly(I:C)誘発IL-6産生におけるIFN-γのプライミング効果2024
- Author(s)
  伊藤政明、大熊範和、清水千義、長谷川敦也、大森慎也、吉田一貴、松岡功
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] マウスの大腸上皮細胞の遺伝子発現に対するP2X4受容体欠損の影響2024
- Author(s)
  吉田一貴、青木亮、萩原武蔵、伊藤政明、松岡功
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] 機械的進展刺激によるマクロファージ活性化における細胞外ヌクレオチドの影響2023
- Author(s)
  伊藤政明、長谷川敦也、大熊範和、吉田一貴、松岡功
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Effects of novel P2Y6 receptor inhibitor on LPS-induced acute lung injury model in mice2023
- Author(s)
  Masa-aki Ito，Tomoyoshi Shimizu, Atsuya Hasegawa, Norikazu Okuma, Kazuki Yoshida, Tomoko Mineno, Isao Matsuoka
- Organizer
  日本薬理学会97年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] ヒト気道上皮NCl-H292細胞のにおけるインターフェロン-γとPoly(I:C)共刺激で誘導される相乗的なIL-６産生機序の解析2023
- Author(s)
  大熊範和，伊藤政明，吉田一貴，松岡功
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Altered gene expression in colon in P2X4 receptor deficient mice2023
- Author(s)
  Kazuki Yoshida，Ryo Aoki，Natsuki Asahina，Yoshiki Morihashi，Masa-aki Ito，Isao Matsuoka
- Organizer
  日本薬理学会97年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Priming effects of IFN-γ on poly(I:C)induced IL 6 production in human bronchial epithelial cells.2023
- Author(s)
  Norikazu Okuma, Masa-aki Ito, Tomoyoshi Shimizu, Atsuya Hasegawa, Shin’ya Omori, Kazuki Yoshida, Isao Matsuoka
- Organizer
  日本薬理学会97年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] マウス骨髄由来マスト細胞におけるインターロイキン６産生に及ぼすＧｉ共役型受容体であるプロスタノイドEP3とアデノシンA3受容体の作用の違い2023
- Author(s)
  大林昂右、朝比奈愛理、伊藤政明、吉田一貴、松岡功
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] マクロファージの機能に対する機械的伸展刺激の影響2023
- Author(s)
  長谷川敦也，伊藤政明，吉田一貴，松岡功
- Organizer
  147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Do hypotonicity and accessory proteins required for Maxi-Cl channel affect SLCO2A1-mediated prostaglandin E2 transport activity?2023
- Author(s)
  Yoshinobu Nakamura, Masa-aki Ito, Yukino Hoshino, Isao Matsuoka, Takeo Nakanishi,
- Organizer
  日本薬物動態学会第38年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] LPS誘発急性肺障害モデルマウスにおける新規P2Y6受容体阻害剤の薬効解析2023
- Author(s)
  清水千義、伊藤政明、峯野知子、吉田一貴、松岡功
- Organizer
  147回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] P-gp-mediated drug-drug interaction promotes gastrointestinal absorption of pimozide and the risk of QT prolongation due to hERG channel inhibition-Fundamental studies and validation in clinical practice.2023
- Author(s)
  Liyanage Manosika Buddhini Perera, Hiroki Morishita, Masa-aki Ito, Hiroki Sunakawa, Takuo Ogihara.
- Organizer
  日本医療薬学会第33年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Effects of extracellular nucleotides on macrophage activation induced by stretch-mediated mechanical stimulation.2022
- Author(s)
  Masa-aki Ito，Atsuya Hasegawa，Norikazu Okuma，Kazuki Yoshida，Isao Matsuoka
- Organizer
  日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] P2X4受容体は偽アレルギー反応を増強する2022
- Author(s)
  吉田一貴，谷原祥太, 宮下友希, 大林晃右, 伊藤政明, 松岡功
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] Effects of hypotonic stress on prostaglandin E2 transport and Maxi-Cl channel activities of SLCO2A12022
- Author(s)
  Yoshinobu Nakamura, Masa-aki Ito, Toshiaki Okada, Yasunobu Okada, Isao Matsuoka, Takeo Nakanishi
- Organizer
  日本生理学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] P2X4受容体は偽アレルギー反応を増強する2022
- Author(s)
  吉田一貴，谷原祥太, 宮下友希, 大林晃右, 伊藤政明, 松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] マスト細胞におけるATPとPGE2の共刺激による相乗的サイトカイン産生2022
- Author(s)
  大林昂右，吉田一貴，伊藤政明，松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] P2X4 receptor signaling potentiate Mas-relate G protein-coupled receptor B2-induced mast cell degranulation2022
- Author(s)
  Kazuki Yoshida，Kousuke Obayashi，Syouta Tanihara，Yuuki Miyashita，Masa-aki Ito，Isao Matsuoka,
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] ヒト気道上皮NCl-H292細胞のサイトカイン産生における IFN-γとPoly(I:C)の相乗効果2022
- Author(s)
  大熊範和, 伊藤政明, 吉田一貴, 松岡功
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] 炎症病態モデルマウスにおける腸間膜動脈の血管機能解2022
- Author(s)
  秋吉玲未乃，伊藤政明，吉田一貴，松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] ヒト神経膠芽腫A172細胞におけるATPによるインターロイキン６産生亢進作用の解析2022
- Author(s)
  青木楓佳, 伊藤政明, 吉田一貴, 松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Effects of stretch-induced mechanical stimulation on macrophage function.2022
- Author(s)
  Masa-aki Ito，Kazuki Yoshida，Isao Matsuoka
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] ヒト気道上皮NCl-H292細胞のサイトカイン産生における IFN-γとPoly(I:C)の相乗効果2022
- Author(s)
  大熊範和, 伊藤政明, 吉田一貴, 松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] 低張性刺激がSLCO2A1のプロスタグランジンE2輸送能に及ぼす影響2022
- Author(s)
  中村吉伸, 伊藤政明, 岡田俊昭, 岡田泰伸, 松岡功, 中西猛夫
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] ヒト神経膠芽腫A172細胞におけるATPによるインターロイキン６産生亢進作用の解析2022
- Author(s)
  青木楓佳, 伊藤政明, 吉田一貴, 松岡功
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] マスト細胞におけるATPとPGE2の共刺激による相乗的サイトカイン産生2022
- Author(s)
  大林昂右，吉田一貴，伊藤政明，松岡功
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] Effect of pimozide accumulation by P-glycoprotein (P-gp) inhibition on hERG channel on cardiomyocytes2022
- Author(s)
  高橋佳佑, 石井美咲, 森下宙輝, 伊藤政明, 張協義, 上岡宏規, 溝井健太, 矢野健太郎, 荻原琢男
- Organizer
  日本薬剤学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] P2X4 receptor signaling potentiate Mas-relate G protein-coupled receptor B2-induced mast cell degranulation2022
- Author(s)
  Kazuki Yoshida，Kousuke Obayashi，Syouta Tanihara，Yuuki Miyashita，Masa-aki Ito，Isao Matsuoka,
- Organizer
  第95回日本薬理学会年会,
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] IL-33 affects the expression of　purinergic receptors in bone marrow-derived mast cells.2021
- Author(s)
  Kazuki Yoshida，Yuu Ishida，Masaaki Ito，Isao Matsuoka
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] Regulation by purinergic signal of glucose-induced insulin secretion from iGL insulinoma cells.2021
- Author(s)
  Masa-aki Ito，Chinatsu Machida，Kazuki Yoshida，Isao Matsuoka
- Organizer
  第９４回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] Regulation by purinergic signal of glucose-induced insulin secretion from iGL insulinoma cells.2021
- Author(s)
  Masa-aki Ito，Chinatsu Machida，Kazuki Yoshida，Isao Matsuoka
- Organizer
  日本薬理学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] マスト細胞のサイトカイン産出に及ぼす細胞外ATPの作用2021
- Author(s)
  大林昂右，吉田一貴，伊藤政明，松岡功，
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] IL-33 affects the expression of　purinergic receptors in bone marrow-derived mast cells.2021
- Author(s)
  Kazuki Yoshida，Yuu Ishida，Masaaki Ito，Isao Matsuoka
- Organizer
  第９４回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] マウス胸部大動脈器官培養による生理活性物質の血管機能に及ぼす影響の解析，2021
- Author(s)
  伊藤政明，中山睦子，吉田一貴，松岡功
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] マウス胸部大動脈器官培養による生理活性物質の血管機能に及ぼす影響の解析2021
- Author(s)
  伊藤政明，中山睦子，吉田一貴，松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] The effect of P-gp mediated pharmacokinetic interactions on pimozide hERG channel inhibition2021
- Author(s)
  Hiroki Morishita, Keisuke Takahashi, Misaki Ishii, Masa-aki Ito,　Xieyi Zhang, Kenta Mizoi, Kentaro Yano, Takuo Ogihara
- Organizer
  日本薬物動態学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] P2X4受容体が結合組織型マスト細胞の脱顆粒反応に及ぼす影響2021
- Author(s)
  吉田一貴，伊藤政明，松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] マスト細胞のサイトカイン産出に及ぼす細胞外ATPの作用2021
- Author(s)
  大林昂右，吉田一貴，伊藤政明，松岡功
- Organizer
  日本薬学会
- Data Source
  KAKENHI-PROJECT-20K16010
[Presentation] クロメン（ベンゾピラン）骨格を有するP2Y6受容体阻害作用化合物の合成研究2020
- Author(s)
  堤麻香、伊藤政明、松岡功、峯野知子
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] オキサトミド誘導体のヒトP2X7受容体阻害作用2020
- Author(s)
  花岡芙美、宮本美希、福田康進、小峯美香、丹羽綾音、山際教之、吉田一貴、伊藤政明、松岡功
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] Effect of compound48/80 on antigen-dependent degranulation in BMMC2020
- Author(s)
  Yoshida　K，Takao　T，Ito　M， Matsuoka　I
- Organizer
  第93回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] 骨髄由来マスト細胞のプリン受容体発現に対するIL-33の効果2020
- Author(s)
  吉田一貴、石田悠、伊藤政明、松岡功
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] P2Y1受容体を介するIL-8産生に対するスタチンの抑制作用2020
- Author(s)
  伊藤政明、新井祥太、吉田一貴、松岡功
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] Changes of thoracic and mesenteric arterial vascular function in angiotensin II-induced hypertensive mice2020
- Author(s)
  Ito　M, Hayashi　T, Koyama　T,　Yoshida　K, Matsuoka I
- Organizer
  第93回　日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K07328
[Presentation] L6筋芽細胞のP2受容体を介した糖取り込み促進作用.2017
- Author(s)
  深澤翔平，吉田一貴，伊藤政明，松岡功
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] 運動負荷によるマウス耐糖能と腸間膜動脈血管機能の改善，2017
- Author(s)
  伊藤政明，小島卓也，篠原康誉，松岡功
- Organizer
  日本薬学会第137年会
- Place of Presentation
  仙台
- Year and Date
  2017-03-27
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] Effectof dexamethazone on P2X7 receptor expression in mouse mast cells2017
- Author(s)
  Yoshida K, Hoshino Y, Ito M, Matsuoka I
- Organizer
  第90回日本薬理学会年会
- Place of Presentation
  長崎
- Year and Date
  2017-03-15
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] マウスの耐糖能及び腸間膜動脈血管機能に及ぼす運動トレーニングの効果2016
- Author(s)
  伊藤政明，小島卓也，松岡功
- Organizer
  第135回　日本薬理学会関東部会
- Place of Presentation
  浜松
- Year and Date
  2016-10-08
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] Involvement of P2Y2 receptors in ATP-induced glucose uptake in L6 myoblast cells2016
- Author(s)
  Fukasawa K, Yoshida K, Ito M,　Matsuoka I
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] 運動負荷によるマウス耐糖能改善における骨格筋プリン作動性シグナルの関与2016
- Author(s)
  伊藤政明、山田沙織、内津潤紀、木村麻莉子、李周炫、内久根夢希、篠原康誉、吉田一貴、松岡功
- Organizer
  日本薬学会第136年会
- Place of Presentation
  横浜
- Year and Date
  2016-03-29
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] 骨格筋の細胞外ATP分解酵素発現におよぼす運動負荷の影響2015
- Author(s)
  中島千里、染谷理恵、伊藤政明、松岡功
- Organizer
  第133回日本薬理学会関東部会
- Place of Presentation
  千葉
- Year and Date
  2015-10-10
- Data Source
  KAKENHI-PROJECT-15K12707
[Presentation] 血管内皮細胞の細胞外ヌクレオチド分解酵素活性に及ぼすHMG-CoA還元酵素阻害剤の影響2010
- Author(s)
  松岡功、伊藤政明、蓬田伸一
- Organizer
  日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] P2Y_6受容体発現1321N1ヒトアストロサイトーマ細胞におけるUDPによるCa^<2+>シグナルに対するプロスタグランジンE_2の作用2010
- Author(s)
  伊藤政明、松岡功
- Organizer
  日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] P2Y6受容体発現1321N1ヒトアストロサイトーマ細胞におけるUDPによるCa2+シグナルに対するプロスタグランジンE2の作用2010
- Author(s)
  伊藤政明、松岡功
- Organizer
  日本薬理学会年会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] Inhibition of P2Y_6 receptor-induced Ca^<2+> signaling by prostaglandin E_2 in murine J774 macrophages2009
- Author(s)
  伊藤政明、松岡功
- Organizer
  Fukuoka Purine 2009(IUPS 2009サテライト)
- Place of Presentation
  ホテルルイガンズ(福岡)
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] マクロファージのGq-ホスホリパーゼC情報伝達に対するプロスタグランジンE2による抑制性制御2009
- Author(s)
  松岡功、伊藤政明
- Organizer
  日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] マウスマクロファージJ774細胞におけるUDPによるストア作動性Ca2+流入のプロスタグランジンE2による抑制2009
- Author(s)
  伊藤政明松岡功
- Organizer
  日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-03-16
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] Inhibition of P2Y6 receptor-induced Ca2+ signaling by prostaglandin E2 in murine J774 macrophages.2009
- Author(s)
  伊藤政明、松岡功
- Organizer
  Fukuoka Purine 2009(IUPS 2009サテライト)
- Place of Presentation
  ホテルルイガンズ(福岡)
- Year and Date
  2009-07-24
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] マクロファージのGq-ボスホリパーゼC情報伝達に対するプロスタグランジンE_2による抑制性制御2008
- Author(s)
  松岡功、伊藤政明
- Organizer
  日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-18
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] マウスマクロファージJ774細胞におけるUDPによるストア作動性Ca_<2+>流入のプロスタグランジンE2による抑制2008
- Author(s)
  伊藤政明, 松岡功
- Organizer
  日本薬理学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2008-03-16
- Data Source
  KAKENHI-PROJECT-20790074
[Presentation] ホスホリパーゼCの抑制と共役する7回膜貫通型受容体のシグナル伝達機構の解析2008
- Author(s)
  伊藤政明松岡功
- Organizer
  特定領域研究班会議(G蛋白質シグナル)
- Place of Presentation
  NASPAニューオータニ
- Year and Date
  2008-09-19
- Data Source
  KAKENHI-PROJECT-20790074

1. MATSUOKA Isao (10145633)

# of Collaborated Projects: 3 results

# of Collaborated Products: 46 results
2. 吉田一貴 (70803154)

# of Collaborated Projects: 2 results

# of Collaborated Products: 23 results
3. 張協義

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 矢野健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中村吉伸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Masaaki 伊藤 政明

ito masaaki 伊藤 政明

伊藤 政明 イトウ マサアキ

ITOU Masaaki 伊藤 政明

Research Projects

Research Products

Co-Researchers

Analysis of the priming mechanism of IFN-gamma in response to RNA recognition receptor stimulation in airway epithelial cellsPrincipal Investigator

Principal Investigator

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Role of purinergic signaling on macrophage function induced by stretch-mediated mechanical stimulation.Principal Investigator

Principal Investigator

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Review Section

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Establishment of therapeutic basis for allergic diseases targeting P2X4 receptor of mast cells

Principal Investigator

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Review Section

Research Institution

Relationship between enhanced purinergic signalling in skeletal muscle and health promoting effects of exercise training

Principal Investigator

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Research Institution

Novel mechanism for regulation of inflammatory response.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Enhancement of mast cells activation by ATP via P2X4 receptor2024

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[Journal Article] Modulation of prostaglandin transport activity of SLCO2A1 by annexin A2 and S100A102024

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[Journal Article] Amplification of poly(I:C)-induced interleukin-6 production in human bronchial epithelial cells by priming with interferon-γ2023

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[Journal Article] Exploratory study of oxatomide derivatives with high P2X7 receptor inhibitory activity2022

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[Journal Article] Synergistic Cytokine Production by ATP and PGE2 via P2X4 and EP3 Receptors in Mouse Bone-Marrow-Derived Mast Cells2022

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[Journal Article] P-Glycoprotein?Mediated Pharmacokinetic Interactions Increase Pimozide hERG Channel Inhibition2022

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[Journal Article] P2X4 receptor stimulation enhances MrgprB2-mediated mast cell activation and pseudoallergic reactions in mice2022

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[Journal Article] Differential Effects of Gq Protein-Coupled Uridine Receptor Stimulation on IL-8 Production in 1321N1 Human Astrocytoma Cells2022

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Ito Masaaki 伊藤政明

ito masaaki 伊藤政明

伊藤政明イトウマサアキ

ITOU Masaaki 伊藤政明