TOGAWA Hiroko 戸川寛子

Researcher Number	30445093
Affiliation (based on the past Project Information) *help	2014: 和歌山県立医科大学, 医学部, 博士研究員 2013 – 2014: 和歌山県立医科大学, 医学部, 助教 2011 – 2012: 和歌山県立医科大学, 医学部, 博士研究員 2010: Wakayama Medical University, 医学部, 助教 2009: Wakayama Medical University, 和歌山県立医科大学・医学部, 助教 2008: Wakayama Medical University, 医学部, 学内助教
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics
Keywords	Principal Investigator 上皮間葉移行 / 遺伝性腎疾患 / 多発性嚢胞腎 / 上皮間葉移行(EMT) / TGF-β/Smad3 / 疾患特異的治療 / Smad3 / TGF-β / CPKマウス / Na^<+->K^<+->ATPase … More / Na^+-K^+-ATPase / 細胞極性 / エンドサイトーシス / βカテニン / E-カドヘリン / 間葉系マーカー / PCKラット … More Except Principal Investigator 開発 / 新治療法 / IL-18 / IL-1β / caspase 1 / NLRP3 / インフラマソーム / IgA腎症 Less

Role of imflammasome in IgA nephropathy
- Principal Investigator
  
  YOSHIKAWA Norishige
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Pediatrics
- Research Institution
  Wakayama Medical University
Disease specific therapy for polycystic kidney disease based on EMTPrincipal Investigator
- Principal Investigator
  
  TOGAWA Hiroko
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Wakayama Medical University
Abnormalities in cell polarity in polycystic kidney diseasePrincipal Investigator
- Principal Investigator
  
  TOGAWA Hiroko
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Wakayama Medical University

All 2015 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Book

[Book] 腎臓症候群(第2版) -その他の腎臓疾患を含めて- 別冊日本臨床新領域別症候群シリーズ172012
- Author(s)
  戸川寛子,中西浩一,吉川徳茂
- Total Pages
  859
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-24390265
[Journal Article] Renal biopsy criterion in idiopathic nephrotic syndrome with microscopic hematuria at onset2015
- Author(s)
  Hama T, Nakanishi K, Shima Y, Sato M, Mukaiyama H, Togawa H, Hamahira K, Tanaka R, Kaito H, Nozu K, Iijima K, Yoshikawa N
- Journal Title
  
  Pediatr Nephrol
  
  Volume: 30 Issue: 3 Pages: 445-450
- DOI
  10.1007/s00467-014-2946-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390265, KAKENHI-PROJECT-24791082, KAKENHI-PROJECT-26461618, KAKENHI-PROJECT-15K09694, KAKENHI-PROJECT-15K09695
[Journal Article] First Japanese case of Pierson syndrome with mutations in LAMB22013
- Author(s)
  Togawa H, Yoshikawa N, et al
- Journal Title
  
  Pediatr Int
  
  Volume: 55 Issue: 2 Pages: 229-231
- DOI
  10.1111/j.1442-200x.2012.03629.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390265, KAKENHI-PROJECT-24791082
[Journal Article] 髄質嚢胞腎.腎臓症候群(第2版)-その他の腎臓疾患を含めて-2012
- Author(s)
  戸川寛子,中西浩一,吉川徳茂
- Journal Title
  
  別冊日本臨床新領域別症候群シリーズ
  
  Volume: 17 Pages: 600-602
- Data Source
  KAKENHI-PROJECT-23791190
[Journal Article] Epithelial-to-mesenchymal transition in cyst-lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease.2011
- Author(s)
  Togawa H
- Journal Title
  
  Am J Physiol Renal Physiol
  
  Volume: 300
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790739
[Journal Article] Epithelial-to-mesenchymal transition in cyst-lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease.2011
- Author(s)
  Togawa H, Nakanishi K, Mukaiyama H, Hama T, Shima Y, Sako M, Miyajima M, Nozu K, Nishii K, Nagao S, Takahashi H, Iijima K, Yoshikawa N.
- Journal Title
  
  Am J Physiol Renal Physiol. 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790739
[Journal Article] Increased chymase-positive mast cells in children with crescentic glomerulonephritis.2009
- Author(s)
  Togawa H
- Journal Title
  
  Pediatric Nephrology 24
  
  Pages: 1071-1075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790739
[Journal Article] Increased chymase-positive mast cells in children with crescentic glomerulonephritis2009
- Author(s)
  Togawa H
- Journal Title
  
  Pediatr Nephrol 24
  
  Pages: 1071-1075
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] 常染色体劣性多発性嚢胞腎の鑑別を要した3例2013
- Author(s)
  浜武継,中西浩一,佐藤匡,向山弘展,戸川寛子,島友子,辻本弘,神波信次,吉川徳茂
- Organizer
  第35回日本小児腎不全学会学術集会
- Place of Presentation
  郡山
- Year and Date
  2013-10-24
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスにおける病的Smad3リン酸化2013
- Author(s)
  浜武継,中西浩一,向山弘展,戸川寛子,佐藤匡,島友子,宮嶋正康,野津寛大,高橋久英,長尾枝澄香,飯島一誠,吉川徳茂
- Organizer
  第22回発達腎研究会
- Place of Presentation
  高槻
- Year and Date
  2013-09-14
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスARPKDモデルにおける病的Smad3リン酸化2013
- Author(s)
  浜武継,中西浩一,向山弘展,戸川寛子,佐藤匡,島友子,宮嶋正康,野津寛大,高橋久英,長尾枝澄香,飯島一誠,吉川徳茂
- Organizer
  第21回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2013-09-21
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions in Cyst-Lining Epithelia in cpk Mouse, a Model of ARPKD2013
- Author(s)
  Hama T, Nakanishi K, Mukaiyama H, Togawa H, Sato M, Shima Y, Miyajima M, Nozu K, Nagao S, Takahashi H, Iijima K, Yoshikawa N
- Organizer
  46^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions in Cyst-Lining Epithelia in cpk Mouse, a Model of ARPKD.2013
- Author(s)
  Hama T, Nakanishi K, Mukaiyama H, Togawa H, Sato M, Shima Y, Miyajima M, Nozu K, Nagao S, Takahashi H, Iijima K, Yoshikawa N.
- Organizer
  The 46th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Atlanta, USA
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Possible contribution of fibrocytes to renal fibrosis in cpk mouse, a model of ARPKD2013
- Author(s)
  Hama T, Nakanishi K, Mukaiyama H, Sato M, Togawa H, Shima Y, Miyajima M, Takahashi H, Nagao S, Iijima K, Yoshikawa N
- Organizer
  15th Congress of the International Pediatric Nephrology Association
- Place of Presentation
  Shanghai, China
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウス多発性嚢胞腎モデル腎線維化におけるfibrocyteの関与2013
- Author(s)
  浜武継,中西浩一,向山弘展,佐藤匡,戸川寛子,島友子,宮嶋正康,高橋久英,長尾静子,飯島一誠,吉川徳茂
- Organizer
  第48回日本小児腎臓病学会学術集会
- Place of Presentation
  徳島
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Possible Contribution of Fibrocytes to Renal Fibrosis in Cpk Mouse, a Model of ARPKD2012
- Author(s)
  1) Taketsugu Hama, Koichi Nakanishi, Hironobu Mukaiyama, Hiroko Togawa, Yuko Shima, Masayasu Miyajima, Hisahide Takahashi, Shizuko Nagao, Kazumoto Iijima, Norishige Yoshikawa
- Organizer
  45th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Possible Contribution of Fibrocytes to Renal Fibrosis in Cpk Mouse, a Model of ARPKD2012
- Author(s)
  Hama T, Nakanishi K, Mukaiyama H, Togawa H, Shima Y, Miyajima M, Takahashi H, Nagao S, Iijima K, Yoshikawa N
- Organizer
  45^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスにおける部位特定的リン酸化Smad3の発現2012
- Author(s)
  向山弘展,中西浩一,浜武継,戸川寛子,島友子,宮嶋正康,高橋久英,長尾枝澄香,飯島一誠,吉川徳茂
- Organizer
  第47回日本小児腎臓病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスARPKDモデルにおける上皮間葉移行(EMT)2011
- Author(s)
  向山弘展,中西浩一,戸川寛子,濵武継,島友子,宮嶋正康,吉原大輔,長尾枝澄香,高橋久英,飯島一誠,吉川徳茂
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスにおける部位特定的リン酸化Smad3の発現2011
- Author(s)
  浜武継,中西浩一,向山弘展,戸川寛子,島友子,宮嶋正康,高橋久英,長尾枝澄香,飯島一誠,吉川徳茂
- Organizer
  第19回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Year and Date
  2011-09-11
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Acceleration of Smad3 phosphorylation at linker regions via c-Jun NH2-terminal kinase (JNK) in cyst-lining epithelial cells in cpk mouse, a model of ARPKD2011
- Author(s)
  Mukaiyama H, Nakanishi K, Hama T, Togawa H, Shima Y, Miyajima M, Takahashi H, Nagao S, Iijima K, Yoshikawa N
- Organizer
  The 44th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Acceleration of Smad3 phosphorylation at linker regions via c-Jun NH2-terminal kinase (JNK) in cyst-lining epithelial cells in cpk mouse, a model of ARPKD2011
- Author(s)
  Mukaiyama H, Nakanishi K, Hama T, Togawa H, Shima Y, Miyajima M, Takahashi H, Nagao S, Iijima K, Yoshikawa N
- Organizer
  44^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスARPKDモデルにおける上皮間葉移行(EMT)2011
- Author(s)
  向山弘展,中西浩一,戸川寛子,濵武継,島友子,宮嶋正康,吉原大輔,長尾枝澄香,高橋久英,飯島一誠,吉川徳茂
- Organizer
  第54回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] 常染色体劣性多発性嚢胞腎(ARPKD)モデルcpkマウスの尿細管上皮細胞における上皮間葉移行(EMT)2010
- Author(s)
  戸川寛子, 中西浩一, 島友子, 佐古まゆみ, 向山弘展, 宮嶋正康, 野津寛大, 吉原大輔, 長尾枝澄香, 飯島一誠, 吉川徳茂
- Organizer
  第44回日本小児腎臓病学会学術集会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] Epithelial-to-Mesenchymal Transition (EMT) in cpk Mouse, a Model of ARPKD.2010
- Author(s)
  Togawa H, Nakanishi K, Mukaiyama H, Hama T, Shima Y, Miyajima M, Nozu K, Takahashi H, Nagao S, Iijima K, Yoshikawa N.
- Organizer
  43^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Denver, USA
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] ヒトARPKDと相同遺伝子変異を有するPCK ratにおける上皮間葉移行2010
- Author(s)
  戸川寛子, 中西浩一, 島友子, 佐古まゆみ, 向山弘展, 宮嶋正康, 野津寛大, 吉原大輔, 長尾枝澄香, 飯島一誠, 吉川徳茂
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] ARPKD相同遺伝子ラットモデルの尿細管上皮細胞における上皮間葉移行(EMT)2009
- Author(s)
  戸川寛子, 中西浩一, 島友子, 佐古まゆみ. 宮嶋正康, 野津寛大, 飯島一誠, 吉原大輔, 長尾枝澄香, 吉川徳茂
- Organizer
  第44回日本小児腎臓病学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] Snaill Is Involved in Epithelial-to-Mesenchymal Transition (EMT) in Cyst-Lining Epithelial.2009
- Author(s)
  Togawa H, Nakanishi K, Shima Y, Sako M, Miyajima M, Nozu K, Iijima K, Yoshihara D, Nagao S, Yoshikawa N
- Organizer
  42^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] ヒトARPKD相同遺伝子ラットモデルにおける尿細管部位特異的嚢胞形成2009
- Author(s)
  戸川寛子, 中西浩一, 島友子, 佐古まゆみ, 宮嶋正康, 西井一宏, 長尾枝澄香, 高橋久英, 吉川徳茂
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] ヒトARPKD相同遺伝子ラットモデルにおける尿細管部位特異的嚢胞形成.2009
- Author(s)
  戸川寛子
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  パシイフイコ横浜(神奈川県)
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] Snail1 Is Involved in Epithelial-to-Mesenchymal Transition (EMT) in Cyst-Lining Epithelial Cells in PCK Rat.2009
- Author(s)
  Togawa H
- Organizer
  42^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] ARPKD相同遺伝子ラットモデルの尿細管上皮細胞における上皮間葉移行(EMT).2009
- Author(s)
  戸川寛子
- Organizer
  第44回日本小児腎臓病学会学術集会
- Place of Presentation
  一橋記念講堂・学術センター(東京都)
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] Epithelial-to-mesenchymal transition (EMT) in cyst-lining epithelial cells in PCK rat2008
- Author(s)
  Hiroko Togawa
- Organizer
  The 41th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2008-11-07
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] Epithelial-to-Mesenchymal Transition in Cyst-Lining Epithelial Cells in PCK Rat. J Am Soc Nephrol 19 : 362A2008
- Author(s)
  Togawa H, Nakanishi K, Obana M, Shima Y, Miyajima M, Nozu K, Iijima K, Nishi K, Nagao S, Takahashi H, Yoshikawa N
- Organizer
  2008 41^<th> Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] 多発性嚢胞腎(PKD)の嚢胞形成にはE-cadherin/β-cateninの破綻が関与する2008
- Author(s)
  戸川寛子, 中西浩一, 佐古まゆみ, 尾鼻美奈, 島友子, 宮嶋正康, 西井一宏, 長尾枝澄香, 高橋久英, 吉川徳茂
- Organizer
  第43回日本小児腎臓病学会学術集会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20790739
[Presentation] cpkマウスARPKDモデルにおける病的Smad3リン酸化
- Author(s)
  浜武継, 中西浩一, 向山弘展, 戸川寛子, 佐藤匡, 島友子, 宮嶋正康, 野津寛大, 高橋久英, 長尾枝澄香, 飯島一誠, 吉川徳茂
- Organizer
  第21回嚢胞性腎疾患研究会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] cpkマウスにおける病的Smad3リン酸化
- Author(s)
  浜武継, 中西浩一, 向山弘展, 戸川寛子, 佐藤匡, 島友子, 宮嶋正康, 野津寛大, 高橋久英, 長尾枝澄香, 飯島一誠, 吉川徳茂
- Organizer
  第22回発達腎研究会
- Place of Presentation
  高槻
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] 常染色体劣性多発性嚢胞腎の鑑別を要した3例
- Author(s)
  浜武継, 中西浩一, 佐藤匡, 向山弘展, 戸川寛子, 島友子, 辻本弘, 神波信次, 吉川徳茂
- Organizer
  第35回日本小児腎不全学会学術集会
- Place of Presentation
  郡山
- Data Source
  KAKENHI-PROJECT-23791190
[Presentation] Smad3 gene deletion ameliorates cyst formation and interstitial fibrosis in cpk mouse, a model of ARPKD
- Author(s)
  Hama T, Nakanishi K, Mukaiyama H, Togawa H, Sato M, Shima Y, Miyajima M, Nozu K, Nagao S, Takahashi H, Iijima K, Yoshikawa N
- Organizer
  47th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24390265
[Presentation] IgA nephropathy with nephrotic syndrome in children
- Author(s)
  Shima Y, Nakanishi K, Hama T, Sato M, Mukaiyama H, Togawa H, Kaito H, Nozu K, Tanaka R, Iijima K, Yoshikawa N
- Organizer
  47th Annual Meeting of the American Society of Nephrology
- Place of Presentation
  Philadelphia, USA
- Year and Date
  2014-11-11 – 2014-11-16
- Data Source
  KAKENHI-PROJECT-24390265

1. YOSHIKAWA Norishige (10158412)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. NAKANISHI Koichi (50336880)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. SHIMA Yuko (60433364)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. MUKAIYAMA Hironobu (70549740)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. HAMA Taketsugu (00508020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

TOGAWA Hiroko 戸川 寛子

Research Projects

Research Products

Co-Researchers

Role of imflammasome in IgA nephropathy

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Disease specific therapy for polycystic kidney disease based on EMTPrincipal Investigator

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Abnormalities in cell polarity in polycystic kidney diseasePrincipal Investigator

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[Book] 腎臓症候群(第2版) -その他の腎臓疾患を含めて- 別冊日本臨床 新領域別症候群シリーズ172012

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[Journal Article] Renal biopsy criterion in idiopathic nephrotic syndrome with microscopic hematuria at onset2015

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[Journal Article] First Japanese case of Pierson syndrome with mutations in LAMB22013

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[Journal Article] 髄質嚢胞腎.腎臓症候群(第2版)-その他の腎臓疾患を含めて-2012

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[Journal Article] Epithelial-to-mesenchymal transition in cyst-lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease.2011

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[Journal Article] Epithelial-to-mesenchymal transition in cyst-lining epithelial cells in an orthologous PCK rat model of autosomal-recessive polycystic kidney disease.2011

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[Journal Article] Increased chymase-positive mast cells in children with crescentic glomerulonephritis.2009

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[Journal Article] Increased chymase-positive mast cells in children with crescentic glomerulonephritis2009

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[Presentation] 常染色体劣性多発性嚢胞腎の鑑別を要した3例2013

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[Presentation] cpkマウスにおける病的Smad3リン酸化2013

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[Presentation] cpkマウスARPKDモデルにおける病的Smad3リン酸化2013

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[Presentation] Smad3 Phosphorylated at Both Linker and COOH-Terminal Regions in Cyst-Lining Epithelia in cpk Mouse, a Model of ARPKD2013

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TOGAWA Hiroko 戸川寛子

[Book] 腎臓症候群(第2版) -その他の腎臓疾患を含めて- 別冊日本臨床新領域別症候群シリーズ172012