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Eitsuka Takahiro  永塚 貴弘

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EITSUKA Takahiro  永塚 貴弘

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Researcher Number 30445895
Other IDs
Affiliation (Current) 2025: 東北大学, 農学研究科, 准教授
Affiliation (based on the past Project Information) *help 2017 – 2025: 東北大学, 農学研究科, 准教授
2014 – 2015: 新潟薬科大学, 応用生物科学部, 助教
2013: 新潟薬科大学, 応用生命科学部, 助教
2010 – 2011: 新潟薬科大学, 応用生命科学部, 助教
2007 – 2008: Nigata University of Phermacy and Applied Life Sciences, 応用生命科学部, 助教
Review Section/Research Field
Principal Investigator
Food science / Basic Section 38050:Food sciences-related
Except Principal Investigator
Basic Section 38050:Food sciences-related / Food science / Medium-sized Section 38:Agricultural chemistry and related fields
Keywords
Principal Investigator
テロメラーゼ / 癌 / 過酸化脂質 / 相乗効果 / 脂質 / 抗癌 / シグナル伝達 / トコトリエノール / テロメア / 細胞老化 … More / 食品機能性成分 / 食品 / 相乗作用 / 癌抑制 / フェルラ酸 / 米ぬか / 糖化脂質 / 糖尿病 / ビタミンE / カロテノイド / 長鎖不飽和脂肪酸 … More
Except Principal Investigator
LC-MS/MS / 過酸化脂質 / 脂質酸化 / フェロトーシス / 酸化機構 / 抗酸化 / 質量分析 / 食品科学 / 健康社会 / 食品 / Peroxide-omics / 酸化ストレス / 酸化メカニズム / 抗酸化食品 / 疾患 / 食品酸化 / 生体酸化 / 酸化制御 / スクアレン / 体臭 / 酸化 / テルペノイド / 食品脂質 / 食品機能 / 疾病 / 抗肥満 / アマドリ-PE / 細胞実験 / 動物実験 / メイラード / ナノ粒子 / メイラード産物 / Amadori-PE / 糖化脂質 Less
  • Research Projects

    (12 results)
  • Research Products

    (83 results)
  • Co-Researchers

    (20 People)
  •  Peroxide-omicsの体系化で脂質酸化の全貌の先(食品の未来品質・ヒトの健康社会)へ迫る

    • Principal Investigator
      仲川 清隆
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tohoku University
  •  Induction of cellular senescence by lipid hydroperoxides and its regulation by food componentsPrincipal Investigator

    • Principal Investigator
      永塚 貴弘
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tohoku University
  •  脂質酸化全貌情報の精緻化から創造する食品の未来品質・ヒトの健康社会

    • Principal Investigator
      仲川 清隆
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tohoku University
  •  Effect of lipid hydroperoxide on cancer progression and its mechanism of actionPrincipal Investigator

    • Principal Investigator
      Eitsuka Takahiro
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tohoku University
  •  Challenges into the definite control of human odor by regulating the oxidation of a newly conceptualized terpenoid "squalene"

    • Principal Investigator
      Nakagawa Kiyotaka
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 38:Agricultural chemistry and related fields
    • Research Institution
      Tohoku University
  •  Elucidation of the lipid oxidation mechanisms and their optimal control leading to a healthy- and food-based society of the future through the analysis of lipid hydroperoxides isomers

    • Principal Investigator
      Nakagawa Kiyotaka
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 38050:Food sciences-related
    • Research Institution
      Tohoku University
  •  Synergistic anti-cancer effects of rice bran components and their mechanisms of actionPrincipal Investigator

    • Principal Investigator
      Eitsuka Takahiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Tohoku University
  •  Elucidation of the mechanism for lipid hydroperoxide generation, its involvement in diseases, and its suppression by dietary components

    • Principal Investigator
      Kiyotaka Nakagawa
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Food science
    • Research Institution
      Tohoku University
  •  Up-regulation of cellular telomerase activity by Amadori-glycated phosphatidylethanolamine: a link between diabetes and cancerPrincipal Investigator

    • Principal Investigator
      Eitsuka Takahiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Food science
    • Research Institution
      Nigata University of Phermacy and Applied Life Sciences
  •  Elucidation of new physiological functions such as anti-obesity and anti-inflammation of food Maillard reaction products

    • Principal Investigator
      Miyazawa Teruo
    • Project Period (FY)
      2013 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Food science
    • Research Institution
      Tohoku University
  •  Telomerase inhibition by carotenoid and its synergistic effect of other constituents in food stuffs.Principal Investigator

    • Principal Investigator
      EITSUKA Takahiro
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Food science
    • Research Institution
      Nigata University of Phermacy and Applied Life Sciences
  •  Anti-tumor effect of functional foods via telomerase inhibition.Principal Investigator

    • Principal Investigator
      EITSUKA Takahiro
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Food science
    • Research Institution
      Nigata University of Phermacy and Applied Life Sciences

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

  • [Book] 食品機能性成分の吸収・代謝・作用機序2018

    • Author(s)
      永塚 貴弘
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Book] 食品機能性成分の吸収・代謝機構2013

    • Author(s)
      永塚貴弘
    • Total Pages
      8
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Book] Tocotrienols : Vitamin E Beyond Tocopherols, Second Edition2012

    • Author(s)
      Takahiro Eitsuka
    • Publisher
      CRC Press
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Book] Tocotrienols : Vitamin E Beyond Tocopherols, Second Edition, Antiangiogenic effects of tocotrienol2012

    • Author(s)
      T. Eitsuka, K. Nakagawa, T. Miyazawa
    • Publisher
      CRC Press
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Book] 機能性食品の作用と安全性百科,ビタミンE循環系に作用する成分-血中、血中脂質、血流などとの関係2012

    • Author(s)
      永塚貴弘
    • Publisher
      丸善出版
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Book] 機能性食品の作用と安全性百科2011

    • Author(s)
      永塚貴弘
    • Publisher
      丸善出版(印刷中)
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Book] Telomerase inhibition(R.R. Watsonand V.R. Preedy ed. Tocotrienols : Vitamin E Beyond Tocopherols,)2009

    • Author(s)
      T. Eitsuka, K. Nakagawa and T. Miyazawa
    • Publisher
      Taylor & Francis Group
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Book] Vitamin E Beyond Tocopherols2008

    • Author(s)
      T. Eitsuka
    • Publisher
      Taylor & Francis Group
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Journal Article] The difference in the cellular uptake of tocopherol and tocotrienol is influenced by their affinities to albumin2023

    • Author(s)
      Nakatomi Takashi、Itaya-Takahashi Mayuko、Horikoshi Yosuke、Shimizu Naoki、Parida Isabella Supardi、Jutanom Mirinthorn、Eitsuka Takahiro、Tanaka Yoshikazu、Zingg Jean-Marc、Matsura Tatsuya、Nakagawa Kiyotaka
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 7392-7392

    • DOI

      10.1038/s41598-023-34584-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K05126, KAKENHI-PLANNED-21H05260
  • [Journal Article] Sheep-derived cell immortalization through the expression of cell cycle regulators and biological characterization using transcriptomes2023

    • Author(s)
      Kikuchi N, Matsusaka H, Bai L, Sano H, Eitsuka T, Nakagawa K, Sugano E, Ozaki T, Tomita H, Kiyono T, Fukuda T.
    • Journal Title

      Cell Biol Int.

      Volume: 47(9) Issue: 9 Pages: 1491-501

    • DOI

      10.1002/cbin.12034

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K09760, KAKENHI-PROJECT-23K05126, KAKENHI-PROJECT-20H03845
  • [Journal Article] Immortalization of primary cells derived from the endangered Ryukyu long-furred rat2023

    • Author(s)
      Bai Lanlan、Kikuchi Noe、Eitsuka Takahiro、Matsusaka Himari、Nakagawa Kiyotaka、Katayama Masafumi、Ito Keiko、Inoue-Murayama Miho、Kiyono Tohru、Fukuda Tomokazu
    • Journal Title

      In Vitro Cellular & Developmental Biology - Animal

      Volume: 59 Issue: 3 Pages: 224-233

    • DOI

      10.1007/s11626-023-00757-3

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K05126, KAKENHI-PROJECT-20H00420
  • [Journal Article] Immortalization of common marmoset-derived fibroblasts via expression of cell cycle regulators using the piggyBac transposon2022

    • Author(s)
      Orimoto Ai、Shinohara Haruka、Eitsuka Takahiro、Nakagawa Kiyotaka、Sasaki Erika、Kiyono Tohru、Fukuda Tomokazu
    • Journal Title

      Tissue and Cell

      Volume: 77 Pages: 101848-101848

    • DOI

      10.1016/j.tice.2022.101848

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09910, KAKENHI-PROJECT-20K05934
  • [Journal Article] Ethanolamine Plasmalogen Suppresses Apoptosis in Human Intestinal Tract Cells in Vitro by Attenuating Induced Inflammatory Stress2021

    • Author(s)
      Nguma Ephantus、Yamashita Shinji、Kumagai Kei、Otoki Yurika、Yamamoto Ayaka、Eitsuka Takahiro、Nakagawa Kiyotaka、Miyazawa Teruo、Kinoshita Mikio
    • Journal Title

      ACS Omega

      Volume: 6 Issue: 4 Pages: 3140-3148

    • DOI

      10.1021/acsomega.0c05545

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K05892, KAKENHI-PROJECT-20K05934
  • [Journal Article] Analysis of oxidation products of α-tocopherol in extra virgin olive oil using liquid chromatography?tandem mass spectrometry2020

    • Author(s)
      Tanno Rena、Kato Shunji、Shimizu Naoki、Ito Junya、Sato Shuntaro、Ogura Yusuke、Sakaino Masayoshi、Sano Takashi、Eitsuka Takahiro、Kuwahara Shigefumi、Miyazawa Teruo、Nakagawa Kiyotaka
    • Journal Title

      Food Chemistry

      Volume: 306 Pages: 125582-125582

    • DOI

      10.1016/j.foodchem.2019.125582

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19H02901, KAKENHI-PROJECT-18J12565, KAKENHI-PROJECT-17K07803
  • [Journal Article] Primary and immortalized cell lines derived from the Amami rabbit (Pentalagus furnessi) and evolutionally conserved cell cycle control with CDK4 and Cyclin D1.2020

    • Author(s)
      Orimoto A, Katayama M, Tani T, Ito K, Eitsuka T, Nakagawa K, Inoue-Murayama M, Onuma M, Kiyono T, Fukuda T
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 525 Issue: 4 Pages: 1046-1053

    • DOI

      10.1016/j.bbrc.2020.03.036

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K19426, KAKENHI-PROJECT-17K17588, KAKENHI-PROJECT-17H03624, KAKENHI-PROJECT-16H05801, KAKENHI-PROJECT-20K05934, KAKENHI-PUBLICLY-19H04904, KAKENHI-PROJECT-19K22670, KAKENHI-PROJECT-20H00420
  • [Journal Article] Correction: Establishment of immortalized primary cell from the critically endangered Bonin flying fox (Pteropus pselaphon)2020

    • Author(s)
      Tani Tetsuya、Eitsuka Takahiro、Katayama Masafumi、Nagamine Takashi、Nakaya Yumiko、Suzuki Hajime、Kiyono Tohru、Nakagawa Kiyotaka、Inoue-Murayama Miho、Onuma Manabu、Fukuda Tomokazu
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 5 Pages: e0234054-e0234054

    • DOI

      10.1371/journal.pone.0234054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K05934
  • [Journal Article] Efficient immortalization of human dental pulp stem cells with expression of cell cycle regulators with the intact chromosomal condition2020

    • Author(s)
      Orimoto Ai、Kyakumoto Seiko、Eitsuka Takahiro、Nakagawa Kiyotaka、Kiyono Tohru、Fukuda Tomokazu
    • Journal Title

      PLOS ONE

      Volume: 15 Issue: 3 Pages: e0229996-e0229996

    • DOI

      10.1371/journal.pone.0229996

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K17588, KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-19K22670
  • [Journal Article] Establishment of immortalized primary cell from the critically endangered Bonin flying fox (Pteropus pselaphon)2019

    • Author(s)
      Tani T, Eitsuka T, Katayama M, Nagamine T, Nakaya Y, Suzuki H, Kiyono T, Nakagawa K, Inoue-Murayama M, Onuma M, Fukuda T
    • Journal Title

      PLoS One

      Volume: 14 Issue: 8 Pages: e0221364-e0221364

    • DOI

      10.1371/journal.pone.0221364

    • NAID

      120006863529

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H03624, KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-16H05801, KAKENHI-PUBLICLY-19H04904, KAKENHI-PROJECT-19K22670
  • [Journal Article] Expression of mutant Cyclin-dependent-kinase, CyclinD, and TERT extends the proliferation period until senescence in chicken and Okinawa rail derived fibroblasts2019

    • Author(s)
      Katayama M, Kiyono T, Ohmaki H, Eitsuka T, Endo D, Inoue-Murayama M, Nakajima N, Onuma M, Fukuda T
    • Journal Title

      Journal of Cellular Physiology

      Volume: 234 Issue: 5 Pages: 6709-6720

    • DOI

      10.1002/jcp.27417

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03624, KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-16H05801, KAKENHI-PUBLICLY-19H04904
  • [Journal Article] Efficient immortalization of cells derived from critically endangered Tsushima leopard cat (Prionailurus bengalensis euptilurus) with expression of mutant CDK4, Cyclin D1, and telomerase reverse transcriptase.2018

    • Author(s)
      Gouko R, Onuma M, Eitsuka T, Katayama M, Takahashi K, Nakagawa K, Inoue-Murayama M, Kiyono T, Fukuda T.
    • Journal Title

      Cytotechnology

      Volume: 70 Issue: 6 Pages: 1619-1630

    • DOI

      10.1007/s10616-018-0254-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-17K19426, KAKENHI-PROJECT-17H03624, KAKENHI-PROJECT-16H05801
  • [Journal Article] Expression of human mutant cyclin dependent kinase 4, Cyclin D and telomerase extends the life span but does not immortalize fibroblasts derived from loggerhead sea turtle (Caretta caretta).2018

    • Author(s)
      Fukuda T, Eitsuka T, Donai K, Kurita M, Saito T, Okamoto H, Kinoshita K, Katayama M, Nitto H, Uchida T, Onuma M, Sone H, Inoue-Murayama M, Kiyono T.
    • Journal Title

      Sci Rep

      Volume: 8 Issue: 1 Pages: 9229-9229

    • DOI

      10.1038/s41598-018-27271-x

    • NAID

      120006979734

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07803, KAKENHI-PROJECT-17K19426, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-15H01749, KAKENHI-PROJECT-17H03624, KAKENHI-PLANNED-25118005, KAKENHI-PROJECT-26252064, KAKENHI-PROJECT-16H05801
  • [Journal Article] Determination of triacylglycerol oxidation mechanisms in canola oil using liquid chromatography-tandem mass spectrometry.2018

    • Author(s)
      Kato S, Shimizu N, Hanzawa Y, Otoki Y, Ito J, Kimura F, Takekoshi S, Sakaino M, Sano T, Eitsuka T, Miyazawa T, Nakagawa K.
    • Journal Title

      Science of Food

      Volume: - Issue: 1 Pages: 1-11

    • DOI

      10.1038/s41538-017-0009-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08721, KAKENHI-PROJECT-15H04497
  • [Journal Article] Modulation of Telomerase Activity in Cancer Cells by Dietary Compounds: A Review2018

    • Author(s)
      Eitsuka, T., Nakagawa, K., Kato, S., Ito, J., Otoki, Y., Takasu, S., Shimizu, N., Takahashi, T., Miyazawa, T.
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 19 Issue: 2 Pages: 478-478

    • DOI

      10.3390/ijms19020478

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Journal Article] Mass Spectrometric Discrimination of Squalene Monohydroperoxide Isomers2017

    • Author(s)
      Shimizu, N., Bersabe, H., Ito, J., Kato, S., Towada, R., Eitsuka, T., Kuwahara, S., Miyazawa, T., Nakagawa, K.
    • Journal Title

      J. Oleo Sci.

      Volume: 66 Issue: 3 Pages: 227-234

    • DOI

      10.5650/jos.ess16159

    • NAID

      130005397217

    • ISSN
      1345-8957, 1347-3352
    • Language
      English
    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15H04497, KAKENHI-PROJECT-16H06637
  • [Journal Article] こめ油成分を活用した相乗的ながん抑制効果2017

    • Author(s)
      永塚 貴弘, 西田 浩志, 仲川 清隆, 宮澤 陽夫
    • Journal Title

      オレオサイエンス

      Volume: 17 Pages: 261-268

    • NAID

      130007687673

    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Journal Article] 脂溶性栄養成分によるがん抑制に関する食品学的研究2017

    • Author(s)
      永塚貴弘
    • Journal Title

      日本栄養食糧学会誌

      Volume: 70 Pages: 263-269

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Journal Article] Squalene inhibits ATM-dependent signaling in γIR-induced DNA damage response through induction of Wip1 phosphatase.2016

    • Author(s)
      N. Tatewaki, T. Konishi, Y. Nakajima, M. Nishida, M. Saito, T. Eitsuka, T. Sakamaki, N. Ikekawa, H. Nishida
    • Journal Title

      PLoS One

      Volume: 11 Issue: 1 Pages: e0147570-e0147570

    • DOI

      10.1371/journal.pone.0147570

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Journal Article] A combination of δ-tocotrienol and ferulic acid synergistically inhibits telomerase activity in DLD-1 human colorectal adenocarcinoma cells.2016

    • Author(s)
      T. Eitsuka, N. Tatewaki, H. Nishida, K. Nakagawa, T. Miyazawa
    • Journal Title

      J. Nutr. Sci. Vitaminol.

      Volume: 印刷中

    • NAID

      130005179347

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Journal Article] Establishment of an immortalized cell line derived from the prairie vole via lentivirus-mediated transduction of mutant cyclin-dependent kinase 4, cyclin D, and telomerase reverse transcriptase2016

    • Author(s)
      Katayama M, Kiyono T, Horie K, Hirayama T, Eitsuka T, Kuroda K, Donai K, Hidema S, Nishimori K and Fukuda T
    • Journal Title

      Exp. Anim.

      Volume: 65 Issue: 1 Pages: 87-96

    • DOI

      10.1538/expanim.15-0061

    • NAID

      130005125854

    • ISSN
      0007-5124, 1341-1357, 1881-7122
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02442, KAKENHI-PROJECT-13J04781, KAKENHI-PROJECT-14J05415, KAKENHI-PROJECT-25450185
  • [Journal Article] Bovine and porcine fibroblasts can be immortalized with intact karyotype by the expression of mutant cyclin dependent kinase 4, cyclin D, and telomerase.2014

    • Author(s)
      Donai K, Kiyono T, Eitsuka T, Guo Y, Kuroda K, Sone H, Isogai E, Fukuda T.
    • Journal Title

      J. Biotechnol.

      Volume: 176 Pages: 50-57

    • DOI

      10.1016/j.jbiotec.2014.02.017

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Journal Article] Synergistic inhibition of cancer cell proliferation with a combination of δ-tocotrienol and ferulic acid.2014

    • Author(s)
      Eitsuka T, Tatewaki N, Nishida H, Kurata T, Nakagawa K, Miyazawa T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 453 Issue: 3 Pages: 606-611

    • DOI

      10.1016/j.bbrc.2014.09.126

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24580203, KAKENHI-PROJECT-25293029, KAKENHI-PROJECT-25450185
  • [Journal Article] Amadori-glycated phosphatidylethanolamine up-regulates telomerase activity in PANC-1 human pancreatic carcinoma cells2012

    • Author(s)
      T. Eitsuka, K. Nakagawa, Y. Ono, N. Tatewaki, H. Nishida, T. Kurata, N. Shoji, T. Miyazawa
    • Journal Title

      FEBS Letters

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Journal Article] Efficient establishment of pig embryonic fibroblast cell lines with conditional expression of simian vacuolating virus 40 large T fragment2012

    • Author(s)
      T. Fukuda, M. Katayama, T. Yoshizawa, T. Eitsuka, H. Mizukami, K. Nakagawa, H. Ito, H. Komagata, S. Song, S. Roh, Y. Hoshino, E. Sato, H. Hanada, K. Nishimori, T. Miyazawa, T. Uchida
    • Journal Title

      Biosci. Biotech. Biochem

      Volume: (in press)

    • NAID

      10030982228

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Journal Article] Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol). (review)2009

    • Author(s)
      Miyazawa T, Shibata A, Sookwong P, Kawakami Y, Eitsuka T, et.al.
    • Journal Title

      The Journal of Nutritional Biochemistry 20

      Pages: 79-86

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Journal Article] Antiangiogenic and anticancer potential of unsaturated vitamin E (tocotrienol)2009

    • Author(s)
      T. Miyazawa, A. Shibata, P. Sookwong, Y. Kawakami, T. Eitsuka, A. Asai, S. Oikawa and K. Nakagawa
    • Journal Title

      J. Nutr. Biochem 20

      Pages: 79-86

    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] Exposure of squalene hydroperoxides to photons causes the formation of unique squalene cyclic peroxides via a chain reaction mechanism detected on the human skin and causing harm to skin cells (HaCaT)2021

    • Author(s)
      Saoussane Khalifa, Shunji Kato, Masaru Enomoto, Yurika Otoki, Takahiro Eitsuka, Kiyotaka Nakagawa
    • Organizer
      2021 AOCS Annual Meeting & Expo
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] LC-MS/MSおよびGC-MSによるサメ肝油中のスクアレンの酸化評価2021

    • Author(s)
      清水直紀, 伊藤隼哉, 加藤俊治, 永塚貴弘, 西田浩志, 仲川清隆
    • Organizer
      日本農芸化学会東北支部 第156回大会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] グルコシルセラミドの酸化修飾とCaco-2培養細胞系における抗炎症作用2021

    • Author(s)
      Mirinthorn Jutanom, 加藤俊治, 乙木百合香, 伊藤隼哉, 山下慎司, 木下幹朗, 永塚貴弘, 仲川清隆
    • Organizer
      第75回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] Squalene oxidation products and their effect on the human keratinocyte cell line HaCaT2020

    • Author(s)
      Khalifa Saoussane, Naoki Shimizu, Shunji Kato, Junya Ito, Takahiro Eitsuka, Kiyotaka Nakagawa
    • Organizer
      日本農芸化学会2020年度大会
    • Data Source
      KAKENHI-PROJECT-19K22265
  • [Presentation] スクアレン酸化物の合成・構造解析とヒト表皮角化細胞HaCaTに与える影響の評価2020

    • Author(s)
      Khalifa Saoussane, 加藤俊治, 清水直紀, 伊藤隼哉, 永塚貴弘, 仲川清隆
    • Organizer
      第74回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-19K22265
  • [Presentation] トコトリエノールのがん抑制作用とその高機能化に関する研究2020

    • Author(s)
      永塚貴弘
    • Organizer
      ビタミン学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K05934
  • [Presentation] Determination of triacylglycerol oxidation mechanisms using liquid chromatography-tandem mass spectrometry2019

    • Author(s)
      Shunji Kato, Naoki, Shimizu, Yurika Otoki, Junya Ito, Masayoshi Sakaino, Takashi Sano, Takahiro Eitsuka, Teruo Miyazawa, Kiyotaka Nakagawa
    • Organizer
      American Oil Chemists’ Society (AOCS) Annual Meeting and Expo 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] Squalene oxidation and its effect on human keratinocyte cell line HaCaT2019

    • Author(s)
      Saoussane Khalifa, Naoki Shimizu, Junya Ito, Takahiro Eitsuka, Kiyotaka Nakagawa
    • Organizer
      The 7th International Conference on Food Factors (ICoFF 2019) and The 12th International Conference and Exhibition on Nutraceuticals and Functional Foods (ISNFF 2019)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K22265
  • [Presentation] LC-MS/MSを用いたオリーブ油の酸化メカニズム推定2019

    • Author(s)
      高橋隼登, 加藤俊治, 伊藤隼哉, 境野眞喜, 佐野貴士, 永塚貴弘, 宮澤陽夫, 仲川清隆
    • Organizer
      日本農芸化学会2019年度大会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] ヒト皮脂中のスクアレンの酸化機構解析2019

    • Author(s)
      清水直紀, 伊藤隼哉, 加藤俊治, 永塚貴弘, 仲川清隆
    • Organizer
      日本農芸化学会東北支部第154大会
    • Data Source
      KAKENHI-PROJECT-19K22265
  • [Presentation] サメ肝油中スクアレンの酸化評価とα-トコフェロールによる酸化抑制2019

    • Author(s)
      清水直紀, 伊藤隼哉, 加藤俊治, 永塚貴弘, 齋藤哲男, 西田浩志, 仲川清隆
    • Organizer
      日本ビタミン学会
    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Presentation] リノール酸由来の6種のヒドロペルオキシド異性体とグリシンのメイラード反応2019

    • Author(s)
      仲川清隆, 伊藤隼哉, 加藤俊治, 永塚貴弘
    • Organizer
      第29回日本メイラード学会年会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] 質量分析を用いた油脂初期酸化の新規評価法2019

    • Author(s)
      加藤俊治, 伊藤隼哉, 境野眞善, 佐野貴士, 永塚貴弘, 宮澤陽夫, 仲川清隆
    • Organizer
      日本農芸化学会2019年度大会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] カチオン-π電子相互作用に基づく脂質ヒドロペルオキシドの異性体解析2019

    • Author(s)
      加藤俊治, 乙木百合香, 伊藤隼哉, 永塚貴弘, 仲川清隆
    • Organizer
      日本油化学会第58回年会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] 主要リポタンパクに含まれるコレステロールエステルおよびホスファチジルコリンのヒドロペルオキシド異性体解析2019

    • Author(s)
      大須賀佑輔, 加藤俊治, 伊藤隼哉, 永塚貴弘, 仲川清隆
    • Organizer
      第61回 日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-19H02901
  • [Presentation] トコトリエノールとフェルラ酸による相乗的な癌抑制作用2018

    • Author(s)
      永塚貴弘、仲川清隆、宮澤陽夫
    • Organizer
      第29回ビタミンE研究会
    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Presentation] こめ油成分による相乗的な癌細胞増殖阻害2018

    • Author(s)
      永塚 貴弘, 仲川 清隆, 宮澤 陽夫
    • Organizer
      日本油化学会第57回年会
    • Data Source
      KAKENHI-PROJECT-17K07803
  • [Presentation] 質量分析を用いたオリーブ油の酸化評価と酸化メカニズム推定2017

    • Author(s)
      高橋 隼登, 加藤 俊治, 伊藤 隼哉, 境野 眞善, 佐野 貴士, 永塚貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      日本食品科学工学会平成29年度東北支部大会および市民フォーラム
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] 粉乳に含まれる脂質糖化産物の分析法の構築と腸管吸収の評価2017

    • Author(s)
      伊藤 隼哉, 小舘 愛, 梅津 直生, 乙木 百合香, 加藤 俊治, 池田 郁男, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      第27回日本メイラード学会年会
    • Data Source
      KAKENHI-PROJECT-25252025
  • [Presentation] 過酸化リン脂質(PCOOH)が誘導する細胞死メカニズムの検証2017

    • Author(s)
      伊藤 隼哉, 三上 優依, 勝野 真美, 加藤 俊治, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      第59回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] LC-MS/MSを用いたヒト皮脂中のスクアレン酸化機構の解析2017

    • Author(s)
      清水 直紀, 伊藤 隼哉, 加藤 俊治, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      日本過酸化脂質・抗酸化物質学会第25回年会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] 過酸化脂質の異性体解析を通じた皮脂の酸化機構の解明2017

    • Author(s)
      清水 直紀, 伊藤 隼哉, 加藤 俊治, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      第59回日本脂質生化学会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] ホスファチジルコリンヒドロペルオキシドの細胞毒性に及ぼす抗酸化物質の影響2017

    • Author(s)
      内野 正, 仲川 清隆, 勝野 真美, 伊藤 隼哉, 永塚 貴弘, 宮澤 陽夫, 秋山 卓美, 五十嵐 良明
    • Organizer
      日本過酸化脂質・抗酸化物質学会第25回年会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] アルカリ金属を使用した脂質過酸化物の解析2017

    • Author(s)
      加藤 俊治, 清水 直紀, 乙木 百合香, 伊藤 隼哉, 北谷 佳那恵, 永塚 貴弘, 宮澤 陽夫, 竹越 進, 仲川 清隆
    • Organizer
      日本過酸化脂質・抗酸化物質学会第25回年会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] リノール酸ヒドロペルオキシドとフェロトーシスの関係解明:異性体の違いに着目して2017

    • Author(s)
      伊藤 隼哉, 三上 優依, 勝野 真美, 加藤 俊治, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      第71回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] ビタミン E が過酸化脂質により誘導されるフェロトーシスに与える影響2017

    • Author(s)
      伊藤 隼哉, 三上 優依, 勝野 真美, 加藤 俊治, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      日本ビタミン学会第69回大会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] リノール酸過酸化物を指標とした食品の酸化機構の評価2017

    • Author(s)
      伊藤 隼哉、塩見 大樹、加藤 俊治、永塚 貴弘、宮澤 陽夫、仲川清隆
    • Organizer
      第51回日本栄養・食糧学会東北支部大会(50 周年記念)および市民公開講座
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] ヒト皮脂中のスクアレンヒドロペルオキシド異性体の分析2017

    • Author(s)
      清水 直紀, 伊藤 隼哉, 加藤 俊治, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      第71回日本栄養・食糧学会大会
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] スクアレンヒドロペルオキシド異性体の高選択的な分析法の構築2016

    • Author(s)
      清水 直紀, Hannah Bersabe, 伊藤 隼哉, 加藤 俊治, 十和田 諒, 桑原 重文, 永塚 貴弘, 宮澤 陽夫, 仲川 清隆
    • Organizer
      第50回日本栄養食糧学会東北支部大会
    • Place of Presentation
      岩手大学農学部(岩手県盛岡市)
    • Data Source
      KAKENHI-PROJECT-15H04497
  • [Presentation] Synergistic inhibition of cancer cell growth by a combination of delta-tocotrienol and ferulic acid.2015

    • Author(s)
      T. Eitsuka, N. Tatewaki, H. Nishida, K. Nakagawa, T. Miyazawa
    • Organizer
      12th Asian Congress of Nutrition
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2015-05-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Presentation] Amadori-glycated phosphatidylethanolamine induces cellular telomerase activity.2015

    • Author(s)
      T. Eitsuka, K. Nakagawa, N. Tatewaki, H. Nishida, T. Miyazawa
    • Organizer
      International Symposium on the Maillard Reaction
    • Place of Presentation
      東京大学
    • Year and Date
      2015-09-01
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Presentation] Up-regulation of cellular telomerase activity by Amadori-glycated phosphatidylethanolamine: A link between diabetes and cancer2013

    • Author(s)
      Takahiro Eitsuka, Kiyotaka Nakagawa, Hiroshi Nishida and Teruo Miyazawa
    • Organizer
      Diet and Optimum Health
    • Place of Presentation
      Corvallis, OR, USA
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Presentation] 糖化リン脂質によるテロメラーゼの活性化2013

    • Author(s)
      永塚 貴弘, 仲川 清隆, 西田 浩志, 倉田 忠男, 宮澤 陽夫
    • Organizer
      日本油化学会第52回年会
    • Place of Presentation
      仙台市
    • Data Source
      KAKENHI-PROJECT-25252025
  • [Presentation] トコトリエノールによる細胞分裂寿命の延長2012

    • Author(s)
      永塚貴弘
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2012-03-23
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Presentation] トコトリエノールによるテロメア短縮抑制と分裂寿命の延長2011

    • Author(s)
      永塚貴弘
    • Organizer
      日本ビタミン学会
    • Place of Presentation
      安田女子大学(広島)
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Presentation] トコトリエノールによる細胞分裂寿命の延長~酸化ストレスとテロメアの関わり~2011

    • Author(s)
      永塚貴弘
    • Organizer
      東北大学先端農学シンポジウム
    • Place of Presentation
      東北大学(仙台)(招待講演)
    • Year and Date
      2011-11-24
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Presentation] トコトリエノールによる細胞分裂寿命の延長~酸化ストレスとテロメアの関わり~2011

    • Author(s)
      永塚貴弘
    • Organizer
      東北大学先端農学シンポジウム
    • Place of Presentation
      東北大学(仙台)
    • Year and Date
      2011-11-24
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Presentation] トコトリエノールによるテロメア短縮抑制2011

    • Author(s)
      永塚貴弘
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都女子大学(京都)
    • Year and Date
      2011-03-27
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Presentation] トコトリエノールによるテロメア短縮の抑制効果2010

    • Author(s)
      永塚貴弘
    • Organizer
      日本栄養・食糧学会
    • Place of Presentation
      アスティとくしま(徳島)
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-22780126
  • [Presentation] 長鎖不飽和脂肪酸によるPPARγを介したテロメラーゼ阻害作用2009

    • Author(s)
      永塚貴弘、仲川清隆、三宅紀子、倉田忠男、宮澤陽夫
    • Organizer
      日本農芸化学会
    • Place of Presentation
      福岡(マリンメッセ福岡)
    • Year and Date
      2009-03-29
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] トコトリエノールによるテロメラーゼ阻害とその作用機序2008

    • Author(s)
      永塚貴弘、仲川清隆、三宅紀子、倉田忠男、宮澤陽夫
    • Organizer
      日本農芸化学会
    • Place of Presentation
      名古屋(名城大学天白キャンパス)
    • Year and Date
      2008-03-27
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] Tocotrienol down-regulates cellular telomerase activity in DLD-1 human adenocarcinoma cells2008

    • Author(s)
      Eitsuka, T.
    • Organizer
      4th International Niigata Symposium on Diet and Health
    • Place of Presentation
      新潟(朱鷺メッセ)
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] トコトリエノールによるテロメラーゼ活性の抑制機構2008

    • Author(s)
      永塚貴弘、仲川清隆、三宅紀子、倉田忠男、宮澤陽夫
    • Organizer
      日本ビタミン学会
    • Place of Presentation
      仙台(仙台国際センター)
    • Year and Date
      2008-06-14
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] Tocotrienol down regulates cellular telomerase activity in DLD-1 human adenocarcinoma cells2008

    • Author(s)
      T. Eitsuka, K. Nakagawa, N. Miyake, T. Kurata and T. Miyazawa
    • Organizer
      4th International Niigata Symposium on Diet and Health
    • Place of Presentation
      Niigata(Toki Messe)
    • Year and Date
      2008-11-29
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] トコトリエノールによるテロメラーゼ活性の阻害機構2007

    • Author(s)
      永塚貴弘、仲川清隆、三宅紀子、倉田忠男、宮澤陽夫
    • Organizer
      日本ビタミン学会
    • Place of Presentation
      長崎(ハウステンボス)
    • Year and Date
      2007-05-25
    • Data Source
      KAKENHI-PROJECT-19780105
  • [Presentation] トコトリエノールの抗癌作用に対するフェルラ酸の相乗効果

    • Author(s)
      永塚貴弘、舘脇直人、西田浩志、仲川清隆、宮澤陽夫
    • Organizer
      農芸化学会
    • Place of Presentation
      岡山大学
    • Year and Date
      2015-03-27 – 2015-03-29
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Presentation] 糖化リン脂質による癌細胞テロメラーゼの活性化

    • Author(s)
      永塚貴弘、仲川清隆、西田浩志、倉田忠男、宮澤陽夫
    • Organizer
      日本メイラード学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25450185
  • [Presentation] ビタミンEによるテロメア短縮抑制作用

    • Author(s)
      永塚貴弘、舘脇直人、西田浩志、仲川清隆、宮澤陽夫
    • Organizer
      ビタミンE研究会
    • Place of Presentation
      北里大学
    • Year and Date
      2015-01-09 – 2015-01-10
    • Data Source
      KAKENHI-PROJECT-25450185
  • 1.  Kiyotaka Nakagawa (80361145)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 30 results
  • 2.  伊藤 隼哉 (50781647)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 14 results
  • 3.  加藤 俊治 (60766385)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 11 results
  • 4.  Miyazawa Teruo (20157639)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 13 results
  • 5.  木村 ふみ子 (50321980)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  乙木 百合香 (90812834)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  井上 奈穂 (90510529)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  都築 毅 (00404848)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  内野 正 (40232863)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  FUKUDA Tomokazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 11.  山下 慎司
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  折本 愛
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 13.  村山 美穂
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 14.  大沼 学
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 3 results
  • 15.  西田 浩志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 16.  中嶋 信美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 17.  富田 浩史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 18.  菅野 江里子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 19.  竹腰 進
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  伊藤 英之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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