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Kanno Keishi  菅野 啓司

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KANNO Keishi  菅野 啓司

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Researcher Number 30448237
Other IDs
Affiliation (Current) 2025: 広島大学, 病院(医), 准教授
Affiliation (based on the past Project Information) *help 2017 – 2022: 広島大学, 病院(医), 准教授
2013: 広島大学, 大学病院, 講師
2013: 広島大学, 病院, 助教
2012: 広島大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 53010:Gastroenterology-related
Except Principal Investigator
Gastroenterology / Studies on the Super-Aging Society
Keywords
Principal Investigator
核酸医療 / 肝脂質代謝 / アポトーシス / 細胞外マトリックス蛋白 / 肝脂肪化 / 肝星細胞 / 非アルコール性脂肪性肝炎 / ペリオスチン / 脂肪肝 / 肝線維化 / 非アルコール性脂肪肝炎 / 非アルコール性脂肪性肝疾患 / アンチセンス核酸 … More
Except Principal Investigator
… More 外耳道センサ / 極泉・壇中・翳風センサ / 情動と痛みのデジタル化 / IoTウエアラブルデバイス / ブレインセンシング / 認知症 / ブレインセンシング技術 / 多職種協働 / プライマリ・ケア / 地域包括ケアシステム / ICT / 地域医療 / Society 5.0 / IoTデバイス / 在宅看取り / オンライン診療 / ビッグデータ / IoHウエアラブルデバイス / 看取り / ウェルビーイング / 胆道がん / 硬化性胆管炎 / 腫瘍性コランギオパチー / 劣化脂質 / 胆管 / コランギオパチー / アポトーシス / EMT / ペリオスチン / EMT / 変性脂質 / モノクロナル抗体 / 筋線維芽細胞 / 阻害抗体 / 肺線維化 / 肝線維化 / 肝硬変 / 抗体医薬 / TGF-β / 星細胞 / 線維症 / インテグリン Less
  • Research Projects

    (4 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (19 People)
  •  Study of emotion and the pain to be able to put to nurse you at home using the brain sensing technology.

    • Principal Investigator
      中村 浩士
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Studies on the Super-Aging Society
    • Research Institution
      Department of Clinical Research, National Hospital Organization Kure Medical Center
  •  Pharmaceutical applications of periostin antisenseoligo for non-alcoholic fatty liver diseasePrincipal Investigator

    • Principal Investigator
      Kanno Keishi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Hiroshima University
  •  Pathogenesis and management of carcinogenic cholangiopathy induce by deteriorated lipids

    • Principal Investigator
      Tazuma Susumu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Hiroshima University
  •  Activated hepatic stellate cell specific antibody that attenuates liver fibrosis: mechanism of action and therapeutic use

    • Principal Investigator
      YOKOSAKI Yasuyuki
    • Project Period (FY)
      2012 – 2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Gastroenterology
    • Research Institution
      Hiroshima University

All 2020 2019 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation Other

  • [Journal Article] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in a mouse model of nonalcoholic steatohepatitis2020

    • Author(s)
      Kobayashi T, Kanno K, Nguyen PT, Sugiyama A, Kawahara A, Otani Y, Kishikawa N, Ito M, Tazuma S
    • Journal Title

      J Gastroenterol Hepatol

      Volume: 35 Issue: 12 Pages: 2140-2150

    • DOI

      10.1111/jgh.15088

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07940
  • [Journal Article] Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma2017

    • Author(s)
      Mino M, Kanno K, Okimoto K, Sugiyama A, Kishikawa N, Kobayashi T, Ono J, Izuhara K, Kobayashi T, Ohigashi T, Ohdan H, Tazuma S
    • Journal Title

      Hepatol Commun

      Volume: 1 Issue: 10 Pages: 1099-1109

    • DOI

      10.1002/hep4.1114

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05343, KAKENHI-PROJECT-15K10166, KAKENHI-PROJECT-15K15372, KAKENHI-PROJECT-16K09396
  • [Journal Article] Ursodeoxycholic acid after bile duct stone removal and risk factors2016

    • Author(s)
      Yamamoto R, Tazuma S, Kanno K, Igarashi Y, Inui K, Ohara H, Tsuyuguchi T,
    • Journal Title

      J Hepatobiliary Pancreat Sci.

      Volume: 23 Issue: 2 Pages: 132-136

    • DOI

      10.1002/jhbp.316

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Journal Article] Enhancing hepatic fibrosis in spontaneously hypertensive rats fed a choline-deficient diet: a follow-up report on long-term effects of oxidative2016

    • Author(s)
      Yamamoto H, Kanno K, Ikuta T, Arihiro K, Sugiyama A, Kishikawa N, Tazuma S.
    • Journal Title

      J Hepatobiliary Pancreat Sci.

      Volume: 23 Issue: 5 Pages: 260-269

    • DOI

      10.1002/jhbp.333

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Journal Article] Periostin promotes hepatic fibrosis in mice by modulating2016

    • Author(s)
      Sugiyama A, Kanno K, Nishimichi N, Ohta S, Ono J, Conway SJ, Izuhara K,
    • Journal Title

      J Gastroenterol.

      Volume: 51 Pages: 1161-1174

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Journal Article] Long-term administration of a Niemann-Pick C1-like 1 inhibitor, ezetimibe, does2016

    • Author(s)
      Kishikawa N, Kanno K, Sugiyama A, Yokobayashi K, Mizooka M, Tazuma S.
    • Journal Title

      J Hepatobiliary Pancreat Sci.

      Volume: 23 Issue: 2 Pages: 125-131

    • DOI

      10.1002/jhbp.313

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Presentation] 肝線維化に対する新たな治療戦略-ペリオスチンに対するアンチセンス核酸製剤の有用性2019

    • Author(s)
      小林知貴、菅野啓司、田妻進
    • Organizer
      第105回日本消化器病学会総会
    • Data Source
      KAKENHI-PROJECT-18K07940
  • [Presentation] dca species decreased largely in hepatic bile acid composi­tions of NAFLD animal model with hyperten­sion2018

    • Author(s)
      Kodama M, Tazuma S, Kanno K
    • Organizer
      69th Annual Meeting, American Associa­tion for the Study of Liver Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Presentation] Periostin antisense oligonucleotide prevents hepatic ste­atosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment2018

    • Author(s)
      Kobayashi M, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S
    • Organizer
      9th Annual Meeting, American Association for the Study of Liver Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Presentation] Periostin antisense oligonucleotide prevents hepatic steatosis and fibrosis in mice: A novel strategy for nonalcoholic steatohepatitis treatment.2018

    • Author(s)
      Kobayashi T, Kanno K, Sugiyama A, Nguyen PT, Kishikawa N, Otani Y, Tazuma S
    • Organizer
      69th Annual Meeting, American Association for the Study of Liver Disease
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07940
  • [Presentation] Altered Bile Acid Synthesis Pathway in Hypertentionassociated Non-Alcoholic Steatohepatitis Animal Model.2017

    • Author(s)
      Kodama M, Kanno K, Tazuma S.
    • Organizer
      The 118th AGA meeting (May 6-9, 2017, Chicago, Illinois)
    • Place of Presentation
      Chicago, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Presentation] Periostin promotes malignant potential by induction of epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma.2017

    • Author(s)
      Sugiyama A, Mino M, Kanno K, Ono J, Kishikawa N, Kobayashi T, Kobayashi T, Ohdan H, Tazuma S.
    • Organizer
      The 118th AGA meeting (May 6-9, 2017, Chicago, Illinois)
    • Place of Presentation
      Chicago, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Presentation] An essential role of hepatic cholesterol and bile acid metabolism mediated by nuclear receptors in the development of hypertension-associated non-alcoholic steatohepatitis.2016

    • Author(s)
      Kodama M, Tazuma S, Kanno K.
    • Organizer
      Asian Pacific Digestive Week 2016
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2016-11-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09396
  • [Presentation] Inhibition Of Pulmonary Fibrosis By Integrin α8β1 Blocking Antibody and TGFβ-Independent Myofibroblast Differentiation By α8β1 Mediated Signal2014

    • Author(s)
      Y. Yokosaki, N. Nishimichi, K. Kanno, K. Sentani
    • Organizer
      American Thoracic Society 2014 International Meeting
    • Place of Presentation
      San Diego, CA, USA
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] Myofibroblast Differentiation Mediated By Integrin α8β1.2014

    • Author(s)
      Norihisa Nishimichi, Keishi Kanno, Akiko Sugiyama, Yasuyuki Yokosaki
    • Organizer
      Keystone Symposia
    • Place of Presentation
      Keystone, CO, USA
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] 新しい肺線維化抑制薬シーズインテグリンα8β1阻害抗体2014

    • Author(s)
      横崎恭之、西道教尚、仙谷和弘、菅野啓司、安井弥
    • Organizer
      第54日本呼吸器学会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] A possible therapeutic agent for pulmonary fibrosis: antibody against integrin α8β1.2013

    • Author(s)
      Yokosaki Y, Nishimichi N, Kanno K, Senatani K, Yasui W.
    • Organizer
      European Respiratory Society
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] A possible therapeutic agent for pulmonary fibrosis : antibody against integrinα8β12013

    • Author(s)
      Yokosaki Y, Nishimichi N, Kanno K, Senatani K, Yasui W.
    • Organizer
      European Respiratory Society
    • Place of Presentation
      Barcelona, Spain
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] Integrinα8β1 as a new therapeutic target for tissue fibrosis. American Thoracic Society2012

    • Author(s)
      Norihisa Nishimichi, Keishi Kanno, Neil C. Henderson, Dean Sheppard, Yasuyuki Yokosaki
    • Organizer
      2012 International Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] インテグリンα8β1 は活性化肝星細胞に発現し肝線維化を促進する2012

    • Author(s)
      西道教尚、菅野啓司、仙谷和弘、安井弥、横崎恭之
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] Integrin α8β1 As A New Therapeutic Target For Tissue Fibrosis2012

    • Author(s)
      Norihisa Nishimichi, Keishi Kanno, Neil C. Henderson, Dean Sheppard, Yasuyuki Yokosaki
    • Organizer
      American Thoracic Society, 2012 International Meeting
    • Place of Presentation
      San Francisco, CA, USA
    • Data Source
      KAKENHI-PROJECT-24659367
  • [Presentation] インテグリンα8β1は活性化肝星細胞に発現し肝線維化を促進する2012

    • Author(s)
      西道教尚、菅野啓司、仙谷和弘、安井弥、横崎恭之
    • Organizer
      第35回日本分子生物学会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-24659367
  • []

  • 1.  Tazuma Susumu (80201614)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 2.  小林 知貴 (00817075)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  岸川 暢介 (50711347)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  YOKOSAKI Yasuyuki (80210607)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 5.  SENTANI Kazuhiro (30508164)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 6.  NISHIMICHI Norihisa (00583486)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 7.  大谷 裕一郎 (00817091)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  杉山 晶子 (30788469)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  中村 浩士 (00380006)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  梅本 誠治 (90263772)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  池田 栄二 (30232177)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  中島 翔太 (20580963)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  平野 旭 (60594778)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  加澤 佳奈 (10740102)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  神田 隆 (40204797)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  川井 元晴 (60294641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  松田 守弘 (00362591)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  越久 仁敬 (20252512)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  出原 賢治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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