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Yoshida Koki  吉田 光希

ORCIDConnect your ORCID iD *help
Researcher Number 30453260
Other IDs
Affiliation (Current) 2025: 北海道医療大学, 歯学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 北海道医療大学, 歯学部, 講師
2015 – 2020: 北海道医療大学, 歯学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 57040:Regenerative dentistry and dental engineering-related / Pathobiological dentistry/Dental radiology
Except Principal Investigator
Basic Section 57060:Surgical dentistry-related / Basic Section 57070:Developmental dentistry-related
Keywords
Principal Investigator
エピジェネティクス / エクソソーム / 歯根膜 / 歯髄 / 口腔外歯周組織再生ユニット / 歯周組織再生 / 口腔上皮
Except Principal Investigator
マイクロバイオーム / 加齢 / ストレス … More / reminelarization / エナメル質再石灰化 / amelogenin / DNAメチル化剤 / DNA脱メチル化剤 / エピゲノム / 口腔がん / エナメル質転写因子 / 器官培養 / エナメル質形成不全 / アメロジェニン / CTIP2 / MSX2 Less
  • Research Projects

    (7 results)
  • Research Products

    (18 results)
  • Co-Researchers

    (14 People)
  •  加齢における慢性ストレスでの口腔環境の網羅的解析

    • Principal Investigator
      安彦 善裕
    • Project Period (FY)
      2024 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  歯髄細胞の歯根膜細胞への分化誘導に関わるエクソソームの網羅的解析Principal Investigator

    • Principal Investigator
      吉田 光希
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Construction of enamel self-healing system by amelogenin

    • Principal Investigator
      倉重 圭史
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Comprehensive analysis of epigenomic aberrant genes in oral cancer and verification of tumor suppressive effect by epigenomic drugs.

    • Principal Investigator
      NAGAYASU Hiroki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57060:Surgical dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Control of amelogenesis imperfecta by CTIP2

    • Principal Investigator
      KURASHIGE Yoshihito
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 57070:Developmental dentistry-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Development of extraoral periodontal tissue regeneration unit applying epigenetics to cell sheet engineeringPrincipal Investigator

    • Principal Investigator
      YOSHIDA Koki
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 57040:Regenerative dentistry and dental engineering-related
    • Research Institution
      Health Sciences University of Hokkaido
  •  Identification of the target genes involved in epigenetics with the infection of the oral epitheliumPrincipal Investigator

    • Principal Investigator
      Yoshida Koki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathobiological dentistry/Dental radiology
    • Research Institution
      Health Sciences University of Hokkaido

All 2023 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Direct reprogramming of epithelial cell rests of malassez into mesenchymal-like cells by epigenetic agents2021

    • Author(s)
      Yoshida Koki、Uehara Osamu、Kurashige Yoshihito、Paudel Durga、Onishi Aya、Neopane Puja、Hiraki Daichi、Morikawa Tetsuro、Harada Fumiya、Takai Rie、Sato Jun、Saitoh Masato、Abiko Yoshihiro
    • Journal Title

      Scientific Reports

      Volume: 11 Issue: 1 Pages: 33473142-33473142

    • DOI

      10.1038/s41598-020-79426-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09863, KAKENHI-PROJECT-17K17216, KAKENHI-PROJECT-18K17091
  • [Journal Article] Involvement of RNase 7 in the malignant potential of oral squamous cell carcinoma cells2020

    • Author(s)
      Neopane Puja、Kurashige Yoshihito、Yoshida Koki、Uehara Osamu、Paudel Durga、Morikawa Tetsuro、Sato Jun、Saitoh Masato、Abiko Yoshihiro
    • Journal Title

      Oncology Reports

      Volume: 44 Issue: 3 Pages: 1216-1223

    • DOI

      10.3892/or.2020.7678

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K10213, KAKENHI-PROJECT-18K09863
  • [Presentation] RNA-seqによる歯髄細胞と歯根膜細胞での遺伝子発現解析2023

    • Author(s)
      吉田光希,原田文也,安彦善裕
    • Organizer
      4学会合同学術大会(第43回日本歯科薬物療法学会・第36回日本口腔診断学会・第33回日本口腔内科学会・第32回日本口腔感染症学会)
    • Data Source
      KAKENHI-PROJECT-23K09220
  • [Presentation] Demethylation effect of 5-Azacytidine on oral squamous cell carcinoma2021

    • Author(s)
      Koki Yoshida, Shuhei Takahashi, Fumiya Harada, Dedy Ariwansa, Ariuntsetseg Khurelchuluun, Durga Paudel, Daichi Hiraki, Tetsuro Morikawa, Osamu Uehara, Jun Sato, Yoshihiro Abiko, Hiroki Nagayasu
    • Organizer
      第34回日本口腔診断学会、31回日本口腔内科学会合同開催学会
    • Data Source
      KAKENHI-PROJECT-21K10121
  • [Presentation] 口腔扁平上皮癌におけるエピゲノム薬の腫瘍抑制効果の検討2021

    • Author(s)
      高橋 周平、吉田 光希、原田 文也、Ariwansa Dedy、Khurelchuluun Ariuntsetseg、Paudel Durga、平木 大地、森川 哲郎、植原 治、佐藤 惇、永易 裕樹、安彦 善裕
    • Organizer
      第53回日本臨床分子形態学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-21K10121
  • [Presentation] エピジェネティクスを応用した歯髄細胞の歯根膜様細胞への誘導2020

    • Author(s)
      大西 綾、吉田 光希、高橋 周平、Ariuntsetseg Khurelchuluun、Durga Paudel、平木 大地、森川 哲郎、原田 文也、植原 治、佐藤 惇、永易 裕樹、安彦 善裕
    • Organizer
      第33回日本口腔診断学会・第30回日本口腔内科学会・第13回日本口腔検査学会合同学術大会
    • Data Source
      KAKENHI-PROJECT-18K17091
  • [Presentation] エピジェネティクスを応用したマラッセ上皮-間葉共培養システムの歯根膜特異的遺伝子の解析2019

    • Author(s)
      吉田光希、大西 綾、平木大地、Neopane Puja、Durga Paudel、Ariuntsetseg Khurelchuluun、森川哲郎、佐藤 惇、永易裕樹、安彦善裕
    • Organizer
      第12回日本口腔検査学会・第30回日本臨床口腔病理学会・第29回日本口腔内科学会・第32回日本口腔診断学会 合同学術大会
    • Data Source
      KAKENHI-PROJECT-18K17091
  • [Presentation] エピジェネティクス修飾を応用したマラッセ上皮細胞の脱分化と骨分化誘導能の検討2018

    • Author(s)
      吉田光希、大西 綾、Paudel D、Neopane P、 平木大地、Adhikari BR、 森川哲郎、植原 治、佐藤 惇、西村学子、安彦善裕
    • Organizer
      第29回日本臨床口腔病理学会総会・第11回日本口腔検査学会総会共催学術大会
    • Data Source
      KAKENHI-PROJECT-18K17091
  • [Presentation] LPS長期刺激によるヒト歯肉上皮細胞での老化およびオートファジー遺伝子の発現解析2017

    • Author(s)
      高井理衣、虎谷斉子、植原 治、大西 綾、吉田光希、佐藤 惇、西村学子、安彦善裕、太田 亨
    • Organizer
      第59回歯科基礎医学会学術大会
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] Expression of stem cell markers in ERM by epigenetic agents.2016

    • Author(s)
      Koki Yoshida, Tetsuro Morikawa, Bhoj Raj Adhikari, Fumiya Harada, Masafumi Utsunomiya, Takatoshi Chujo, Rie Takai, Jun Sato, Michiko Nishimura, Yoshihiro Abiko
    • Organizer
      The 93st General Session & Exhibition of the IADR
    • Place of Presentation
      韓国、ソウル
    • Year and Date
      2016-06-22
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] Dedifferentiation of Epithelial rests of Malassez by epigenetic agents.2016

    • Author(s)
      Koki Yoshida, Tetsuro Morikawa, Bhoj Raj Adhikari, Fumiya Harada, Masafumi Utsunomiya, Takatoshi Chujo, Rie Takai, Jun Sato, Michiko Nishimura, Yoshihiro Abiko
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター(宮城県、仙台市)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] タモギタケ由来エルゴチオネインの長期作用による歯肉上皮細胞における遺伝子発現変化のバイオインフォマティクス解析2016

    • Author(s)
      佐藤 惇、森川哲郎、原田文也、Bhoj Raj Adhikari、伊藤-小原 純、中條貴俊、宇津宮雅史、高井理衣、植原 治、吉田光希、西村学子、冨山隆広、安彦善裕
    • Organizer
      第16回日本抗加齢医学会総会
    • Place of Presentation
      パシフィコ横浜会議センター(神奈川県、横浜市)
    • Year and Date
      2016-06-10
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] Upregulated expressions of stem cell markers in Epithelial cell rests of Malassez stimulated with epigenetic agents.2016

    • Author(s)
      Koki Yoshida, Tetsuro Morikawa, Bhoj Raj Adhikari, Fumiya Harada, Takatoshi Chujo, Osamu Uehara, Jun Sato, Michiko Nishimura, Masato Saitoh, Yoshihiro Abiko
    • Organizer
      第58回歯科基礎医学会学術大会
    • Place of Presentation
      札幌コンベンションセンター(北海道、札幌市)
    • Year and Date
      2016-08-24
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] Upregulated expression of SOX2 in ERM cells by epigenetic agents2015

    • Author(s)
      K. YOSHIDA, T. MORIKAWA, B. ADHIKARI, J. ITOH-OBARA, F. HARADA, M. UTSUNOMIYA, T. CHUJO, J. SATO, M. NISHIMURA and Y. ABIKO
    • Organizer
      JADR2015
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] LPS長期刺激による細胞外マトリックス関連遺伝子のDNAメチル化解析2015

    • Author(s)
      高井理衣、植原 治、原田文也、宇津宮雅史、中條貴俊、吉田光希、佐藤 惇、西村学子、千葉逸朗、安彦善裕
    • Organizer
      第57回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Year and Date
      2015-09-11
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] 口腔扁平苔癬における上皮接着関連遺伝子、p16およびMGMTのDNAメチル化解析2015

    • Author(s)
      中條貴俊、Bhoj Raj Adhikari、原田文也、宇津宮雅史、高井理衣、吉田光希、佐藤 惇、西村学子、橋本和彦、松坂賢一、井上 孝、安彦善裕
    • Organizer
      第25回日本口腔内科学会学術大会
    • Place of Presentation
      大阪
    • Year and Date
      2015-09-18
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] 口腔扁平苔癬におけるDNAメチル化解析2015

    • Author(s)
      中條貴俊、Bhoj Raj Adhikari、原田文也、宇津宮雅史、高井理衣、吉田光希、西村学子、橋本和彦、井上 孝、安彦善裕
    • Organizer
      第26回日本臨床口腔病理学会総会・学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2015-07-29
    • Data Source
      KAKENHI-PROJECT-15K20389
  • [Presentation] P. gingivalis由来LPS長期刺激による歯根膜線維芽細胞における細胞外基質タンパク関連遺伝子の高メチル化2015

    • Author(s)
      高井理衣、原田文也、宇津宮雅史、中條貴俊、植原 治、吉田光希、佐藤 惇、西村学子、千葉逸朗、安彦善裕
    • Organizer
      第26回日本臨床口腔病理学会総会・学術大会
    • Place of Presentation
      札幌
    • Year and Date
      2015-07-29
    • Data Source
      KAKENHI-PROJECT-15K20389
  • 1.  植原 治 (00709248)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 2.  安彦 善裕 (90260819)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 3.  KURASHIGE Yoshihito (30453278)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  原田 文也 (30824205)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  NAGAYASU Hiroki (90265075)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  齊藤 正人 (50337036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  村田 佳織 (70781053)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  伊藤 修一 (50382495)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  中尾 友也 (90733048)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  豊福 明 (10258551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  PAUDEL Durga (20910590)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  道川 誠 (40270912)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  藏滿 保宏 (50281811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  長澤 敏行 (90262203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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