Koibuchi Nobutaka 鯉渕信孝

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KOIBUCHI Nobutaka 鯉渕信孝

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Researcher Number	30456131
Other IDs
Affiliation (Current)	2025: 大阪大学, 大学院医学系研究科, 招へい准教授 2025: ぺリオセラピア株式会社, その他部局等, 部長
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院医学系研究科, 招へい准教授 2019: 大阪大学, 医学系研究科, 招へい准教授 2015 – 2018: 熊本大学, 大学院生命科学研究部(医), 助教 2012: 熊本大学, 医学系大学院, 助教 2010: 熊本大学, 生命科学研究部, 助教 … More 2009: The University of Tokyo, 医学部・附属病院, 特任助教 2008 – 2009: The University of Tokyo, 医学部附属病院, 特任助教 2008: 東京大学, 医学部附属病院, 助教 2007: 東京大学, 医学附属病院, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / General anatomy (including histology/embryology) / General anatomy (including Histology/Embryology) Except Principal Investigator Neurosurgery / Circulatory organs internal medicine / Medical systems
Keywords	Principal Investigator 心臓 / 選択的スプライシング / アイソフォーム / ぺリオスチン / 発生・分化 / 分化 / 発生 / 細胞分化 / 心室筋 / 転写因子 … More / 心室 / 中枢神経系 / 神経突起作用 / 保護作用 / 脳梗塞 / ペリオスチン … More Except Principal Investigator ラット / クモ膜下出血 / 視床下部 / 早期脳損傷 / 視床下部室傍核 / 腎除神経術 / 脳血管攣縮 / くも膜下出血 / 翻訳後修飾 / 心筋 / 転写因子 / ANP / Ku80 / Ku70 / DNA-PKcs / リン酸化 / Tbx5 / 分子心臓病学 / 遺伝子治療 / 肝細胞増殖因子 / 遺伝子導入 / 超音波 / 核酸 / 生物物理 / 生物・生体工学 Less

線維化におけるペリオスチンのスプライスシングアイソフォームの機能的差異Principal Investigator
- Principal Investigator
  
  鯉渕信孝
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  Osaka University
Analysis of the mechanism of maturation and differentiation of the heart cells during developmentPrincipal Investigator
- Principal Investigator
  
  Koibuchi Nobutaka
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Osaka University
  Kumamoto University
The beneficial role of renal denervation in the prognosis of subarachnoid hemorrhage
- Principal Investigator
  
  Hasegawa Yu
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Kumamoto University
Posttranscriptional modification of cardiac transcriptional factors and its role in cardiac development
- Principal Investigator
  
  HIROI Yukio
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  The University of Tokyo
Analysis of role of periostin in cerebral functionPrincipal Investigator
- Principal Investigator
  
  KOIBUCHI Nobutaka
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  General anatomy (including Histology/Embryology)
- Research Institution
  The University of Tokyo
Development of Gene Therapy with Ultrasound
- Principal Investigator
  
  TANIYAMA Yoshiaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical systems
- Research Institution
  Osaka University

All 2017 2016 2009 2008

All Journal Article Presentation

[Journal Article] Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome.2017
- Author(s)
  Kusaka H, Koibuchi N, Hasegawa Y, Ogawa H, Kim-Mitsuyama S.
- Journal Title
  
  Cardiovasc Diabetol.
  
  Volume: 15 Pages: 157-157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08469
[Journal Article] Local Production of Activated Factor X in Atherosclerotic Plaque Induced Vascular Smooth Muscle Cell Senescence.2017
- Author(s)
  Sanada F, Muratsu J, Otsu R, Shimizu H, Koibuchi N, Uchida K, Taniyama Y, Yoshimura S, Rakugi H, Morishita R.
- Journal Title
  
  Sci Rep.
  
  Volume: 7 Issue: 1 Pages: 17172-17172
- DOI
  10.1038/s41598-017-17508-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08469
[Journal Article] Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure.2017
- Author(s)
  Takane K, Hasegawa Y, Lin B, Koibuchi N, Cao C, Yokoo T, Kim-Mitsuyama S.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 6 Issue: 4
- DOI
  10.1161/jaha.116.004897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08469
[Journal Article] High-Fat-Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders.2016
- Author(s)
  Lin B, Hasegawa Y, Takane K, Koibuchi N, Cao C, Kim-Mitsuyama S.
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 5 Issue: 6
- DOI
  10.1161/jaha.115.003154
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08469
[Journal Article] Hepatocyte growth factor, but not vascular endothelial growth factor, attenuated angiotensin II-induced EPC senescence2009
- Author(s)
  Sanada F, Taniyama Y, Azuma J, Iekushi K, Dosaka N, Yokoi T, Koibuchi N, Kusunoki H, Aizawa Y, Morishita R.
- Journal Title
  
  Hypertension 53
  
  Pages: 77-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] Hepatocyte growth factor, but not vascular endothelial growth factor, attenuated angiotensin II-induced EPC senescence.2009
- Author(s)
  Sanada F, Taniyama Y, Azuma J, Iekushi K, Dosaka N, Yokoi T, Koibuchi N, Kusunoki H, Aizawa Y, Morishita R.
- Journal Title
  
  Hypertension 53
  
  Pages: 77-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis2009
- Author(s)
  Mori M, Nakagami H, Koibuchi N, Miura K, Takami Y, Koriyama H, Hayashi H, Sabe H, Mochizuki N, Morishita R, Kaneda Y.
- Journal Title
  
  Mol. Biol. Cell 20
  
  Pages: 3115-3124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.2009
- Author(s)
  Mori M, Nakagami H, Koibuchi N, Miura K, Takami Y, Koriyama H, Hayashi H, Sabe H, Mochizuki N, Morishita R, Kaneda Y.
- Journal Title
  
  Mol.Biol.Cell. 20
  
  Pages: 3115-3124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] Negative Action of Hepatocyte Growth Factor/c-Met System on Angiotensin II Signaling via Ligand-Dependent Epithelial Growth Factor Receptor Degradation Mechanism in Vascular Smooth Muscle Cells.2009
- Author(s)
  Sanada F, Taniyama Y, Iekushi K, Azuma J, Okayama K, Kusunoki H, Koibuchi N, Doi T, Aizawa Y, Morishita R.
- Journal Title
  
  Circ.Res. 105
  
  Pages: 667-675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] Negative Action of Hepatocyte Growth Factor/c-Met System on Angiotensin II Signaling via Ligand-Dependent Epithelial Growth Factor Receptor Degradation Mechanism in Vascular Smooth Muscle Cells2009
- Author(s)
  Sanada F, Taniyama Y, Iekushi K, Azuma J, Okayama K, Kusunoki H, Koibuchi N, Doi T, Aizawa Y, Morishita R.
- Journal Title
  
  Circ. Res 105
  
  Pages: 667-675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] A Model of Cerebrovasucular Injury in Rats2008
- Author(s)
  Wakayama K, Shimamura M, Sata M, Koibuchi N, Sato N, Ogihara T, Morishita R.
- Journal Title
  
  J. Neuroscience Methods 175
  
  Pages: 187-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Journal Article] A Model of Cerebrovasucular Injury in Rats.2008
- Author(s)
  Wakayama K, Shimamura M, Sata M, Koibuchi N. Sato N, Ogihara T, Morishita R.
- Journal Title
  
  J. Neuroscience Methods. 175
  
  Pages: 187-195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890046
[Presentation] Hepatocyte growth factor (HGF), but not vascular endothelial growth factor (VEGF), attenuated angiotensin II-induced EC senescence by inhibiting PIP3/raclactivity.2009
- Author(s)
  Sanada F, Taniyama Y, Iekushi K, Dosaka N, Azuma J, Kusunoki H, Koibuchi N, Aizawa Y, Morishita R.
- Organizer
  日本循環器学会
- Place of Presentation
  大阪
- Year and Date
  2009-03-22
- Data Source
  KAKENHI-PROJECT-20890046

1. TANIYAMA Yoshiaki (60372611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. HIROI Yukio (30311624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. Hasegawa Yu (40599114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 河野隆幸 (50448536)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山口雅裕 (00360660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Koibuchi Nobutaka 鯉渕 信孝

KOIBUCHI Nobutaka 鯉渕 信孝

Research Projects

Research Products

Co-Researchers

線維化におけるペリオスチンのスプライスシングアイソフォームの機能的差異Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the mechanism of maturation and differentiation of the heart cells during developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The beneficial role of renal denervation in the prognosis of subarachnoid hemorrhage

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Posttranscriptional modification of cardiac transcriptional factors and its role in cardiac development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of role of periostin in cerebral functionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of Gene Therapy with Ultrasound

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Empagliflozin lessened cardiac injury and reduced visceral adipocyte hypertrophy in prediabetic rats with metabolic syndrome.2017

Author(s)

Journal Title

Data Source

[Journal Article] Local Production of Activated Factor X in Atherosclerotic Plaque Induced Vascular Smooth Muscle Cell Senescence.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detrimental Effects of Centrally Administered Angiotensin II are Enhanced in a Mouse Model of Alzheimer Disease Independently of Blood Pressure.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-Fat-Diet Intake Enhances Cerebral Amyloid Angiopathy and Cognitive Impairment in a Mouse Model of Alzheimer's Disease, Independently of Metabolic Disorders.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hepatocyte growth factor, but not vascular endothelial growth factor, attenuated angiotensin II-induced EPC senescence2009

Author(s)

Journal Title

Data Source

[Journal Article] Hepatocyte growth factor, but not vascular endothelial growth factor, attenuated angiotensin II-induced EPC senescence.2009

Author(s)

Journal Title

Data Source

[Journal Article] Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis2009

Author(s)

Journal Title

Data Source

[Journal Article] Zyxin mediates actin fiber reorganization in epithelial-mesenchymal transition and contributes to endocardial morphogenesis.2009

Author(s)

Journal Title

Data Source

[Journal Article] Negative Action of Hepatocyte Growth Factor/c-Met System on Angiotensin II Signaling via Ligand-Dependent Epithelial Growth Factor Receptor Degradation Mechanism in Vascular Smooth Muscle Cells.2009

Author(s)

Journal Title

Data Source

Koibuchi Nobutaka 鯉渕信孝

KOIBUCHI Nobutaka 鯉渕信孝