KITA KANAKO 喜多加納子

… Alternative Names

Kanako Niimori-Kita 新森加納子

NIIMORI Kanako 新森加納子

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Researcher Number	30457600
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 助教
Affiliation (based on the past Project Information) *help	2021 – 2025: 熊本大学, 大学院生命科学研究部(医), 助教 2019: 熊本大学, 大学院生命科学研究部(医), 助教 2016: 熊本大学, 大学院生命科学研究部(医), 助教 2015: 熊本大学, その他の研究科, 助教 2015: 熊本大学, 生命科学研究部, 助教 … More 2015: 熊本大学, 大学院生命科学研究部, 助教 2014: 熊本大学, 大学院生命科学研究部(医), 助教 2013: 熊本大学, その他の研究科, 助教 2013: 熊本大学, 大学院生命科学研究部, 助教 2013: 熊本大学, 生命科学研究部, 助教 2009 – 2010: 熊本大学, 大学院・生命科学研究部, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 53030:Respiratory medicine-related / Respiratory organ internal medicine / Structural biochemistry Except Principal Investigator Basic Section 49020:Human pathology-related / Human pathology
Keywords	Principal Investigator 肺小細胞癌 / リン酸化 / 神経幹細胞 / 翻訳後修飾 / プロテオミクス / 新規モダリティー / 抗癌剤開発 / 癌治療法 / 神経幹細胞未分化性維持因子 / モダリティー … More / 中分子IT創薬 / 高悪性度癌 / 抗癌剤 / 悪性度 / 質量分析 / 転写調節因子 / 分化制御 / 2D-DIGE / 癌 / 肺小細胞癌治療法 … More Except Principal Investigator プロテオミクス / 個別化医療 / 患者由来 / がんオルガノイド / 抗癌剤 / 薬剤感受性 / 癌オルガノイド / ヒストンアセチル化 / エピジェネティックス / INSM-1 / histone修飾 / epigenetics / 細胞接着 / 神経内分泌分化 / Notch1 / 肺小細胞癌 / ヒストン修飾 / DNAメチル化 / エピジェネティクス / Notchシグナル / 混合型 / 小細胞肺癌 Less

肺小細胞癌の悪性度を司る神経幹細胞未分化性維持因子を標的とした核酸抗癌剤の創出Principal Investigator
- Principal Investigator
  
  喜多加納子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kumamoto University
神経幹細胞未分化性維持因子を標的とした肺小細胞癌新規モダリティーの創出Principal Investigator
- Principal Investigator
  
  喜多加納子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kumamoto University
Screening of biomarkers and targets for cancer therapy by nuclear phosphoproteomics
- Principal Investigator
  
  塚本善之
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Oita University
Development of small cell lung cancer therapy targeting neural stem cell undifferentiation maintenance factorsPrincipal Investigator
- Principal Investigator
  
  KITA KANAKO
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Kumamoto University
Development of a small cell lung cancer treatment method being applied the disruption of its molecular basis of the neural stem cell undifferentiated maintenance factorPrincipal Investigator
- Principal Investigator
  
  Kanako Niimori-Kita
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
Mechanisms on genesis of combined type small cell carcinoma; a study focusing on Notch signaling
- Principal Investigator
  
  Ito Takaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kumamoto University
Elucidation of malignancy and immaturity in lung small cell carcinoma using a neural stem cell novel factor detected by posttranslational modification proteomicsPrincipal Investigator
- Principal Investigator
  
  Niimori Kanako
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
The molecular regulation of differentiation, proliferation and highly malignancy character of small cell lung cancer by proteomic analysis of post-translational modification.Principal Investigator
- Principal Investigator
  
  Niimori Kanako
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Kumamoto University
Identification of post-translational modification in nuclear proteins during neural stem cell fate specification by proteomic analysisPrincipal Investigator
- Principal Investigator
  
  NIIMORI Kanako
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kumamoto University

All 2016 2015 2014 2013 2010 2009

All Journal Article Presentation Patent

[Journal Article] Notch1 controls cell chemo-resistance in small cell lung carcinoma cells.2016
- Author(s)
  Hassan WA, Yoshida R, Kudoh S, Kameyama H, Hasegawa K, Niimori-Kita K, Ito T
- Journal Title
  
  Thoracic Cancer
  
  Volume: 7 Issue: 1 Pages: 123-128
- DOI
  10.1111/1759-7714.12297
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25460439, KAKENHI-PROJECT-26460453
[Journal Article] NEPA21 is usuful for elucidating malignancy and undifferentiation of cancer cells2016
- Author(s)
  平川一憲, 早川靖彦, 新森加納子
- Journal Title
  
  別冊BIO Clinica（バイオクリニカ）慢性炎症と疾患
  
  Volume: Vol.5 No.1 Pages: 118-123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670400
[Journal Article] Insulinoma-Associated protein 1 is a crucial regulator of neuroendocrine differentiation in lung cancer2015
- Author(s)
  Fujino, Kosuke; Motooka, Yamato; Wael, Hassan; Ali Abdalla, Mohamed; Sato, Yonosuke; Kudoh, Shinji; Hasegawa, Koki; Niimori-Kita, Kanako; Kobayashi, Hironori; Kubota, Ichiro; Wakimoto, Joeji; Suzuki, Makoto; Takaaki, Ito
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 185 Issue: 12 Pages: 3164-3177
- DOI
  10.1016/j.ajpath.2015.08.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460453, KAKENHI-PROJECT-25670400, KAKENHI-PROJECT-25460439
[Journal Article] Phosphoproteomics illuminates a new molecule in stem cell maintenance.2015
- Author(s)
  Kanako Niimori-Kita
- Journal Title
  
  Proceedings of Japan and the Netherland on Soft Tribology
  
  Volume: Voi.1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670400
[Journal Article] Sex differences in shotgun proteome analyses for chronic oral intake of cadmium in mice2015
- Author(s)
  Yamanobe Y, Nagahara N, Matsukawa T, Ito T, Niimori-Kita K, Chiba M, Yokoyama K, Takizawa T
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 3 Pages: 1-20
- DOI
  10.1371/journal.pone.0121819
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590392, KAKENHI-PROJECT-15K08322, KAKENHI-PROJECT-25670400
[Journal Article] Overexpression of nucleostemin contributes to an advanced malignant phenotype and a poor prognosis in oral squamous cell carcinoma.2014
- Author(s)
  Yoshida R, Nakayama H, Nagata Y, Hirosue A, Tanaka T, Kawahara K, Nakagawa Y, Matsuoka Y, Sakata J, Akita H, Hiraki A, Shinohara M, and Ito T
- Journal Title
  
  Brit J Cancer
  
  Volume: 111 Issue: 12 Pages: 2308-2315
- DOI
  10.1038/bjc.2014.539
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460439, KAKENHI-PROJECT-25461918, KAKENHI-PROJECT-26861736
[Journal Article] Notch1 controls cell invasion and metastasis in small cell lung carcinoma cell lines.2014
- Author(s)
  Hassan WA, Yoshida R, Kudoh S, Hasegawa K, Niimori-Kita K, and Ito T
- Journal Title
  
  Lung Cancer
  
  Volume: 86 Pages: 304-310
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460439
[Journal Article] Notch1 Signaling Controls Cell Proliferation, Apoptosis and Differentiation in Lung Carcinoma2014
- Author(s)
  Hassan W, Yoshida R, Kudoh S, Hasegawa K, Niimori-Kita K, and Ito T
- Journal Title
  
  Lung Cancer
  
  Volume: 84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460439
[Journal Article] Notch1 signaling controls cell proliferation, apoptosis and differentiation in lung carcinoma.2014
- Author(s)
  Wael H, Yoshida R, Kudoh S, Hasegawa K, Kita-Niimori K, and Ito T
- Journal Title
  
  Lung Cancer
  
  Volume: 85 Pages: 131-140
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460439
[Patent] 癌治療薬剤ならびに治療方法2015
- Inventor(s)
  新森加納子
- Industrial Property Rights Holder
  新森加納子
- Industrial Property Rights Type
  特許
- Filing Date
  2015-06-25
- Overseas
- Data Source
  KAKENHI-PROJECT-25670400
[Patent] 二次元電気泳動による蛋白質の分離方法2013
- Inventor(s)
  新森加納子、伊藤隆明、田賀哲也
- Industrial Property Rights Holder
  新森加納子、伊藤隆明、田賀哲也
- Industrial Property Rights Type
  特許
- Filing Date
  2013-04-04
- Acquisition Date
  2016-02-02
- Data Source
  KAKENHI-PROJECT-25670400
[Presentation] 腫瘍マーカーの発見から再生医療にまで役立つ蛋白質スクリーニング技術を熊本の企業に還元する。2015
- Author(s)
  新森加納子
- Organizer
  第19 回熊本市役所複数企業産学相談会
- Place of Presentation
  熊本市役所
- Year and Date
  2015-04-23
- Invited
- Data Source
  KAKENHI-PROJECT-25670400
[Presentation] 神経幹細胞に係る新規因子を用いて肺癌の悪性度・未熟性を解明する。2015
- Author(s)
  新森加納子
- Organizer
  第33回日本ヒト細胞学会
- Place of Presentation
  宮崎県・ホテルスカイタワー
- Year and Date
  2015-08-22
- Invited
- Data Source
  KAKENHI-PROJECT-25670400
[Presentation] 幹細胞制御因子欠損法による癌治療～そして翻訳後修飾プロテオミクス解析は癌治療に2015
- Author(s)
  新森加納子
- Organizer
  バイオジャパン2015
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670400
[Presentation] 神経幹細胞に係る新規因子を用いて肺癌の悪性度・未熟性を解明する。2015
- Author(s)
  新森加納子
- Organizer
  第47回日本臨床分子形態学会
- Place of Presentation
  長崎大学医学部
- Year and Date
  2015-09-18
- Invited
- Data Source
  KAKENHI-PROJECT-25670400
[Presentation] Phosphoproteomics illuminates a new molecule in stem cell maintenance.2015
- Author(s)
  Kanako Niimori-Kita
- Organizer
  Japan-the Netherlands Symposium on Soft-Tribology
- Place of Presentation
  熊本大学
- Year and Date
  2015-09-12
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25670400
[Presentation] 翻訳後修飾を指標にしたマウス神経幹細胞の分化の運命づけを司る核内分子の探索2010
- Author(s)
  新森加納子
- Organizer
  2010年度・第138回発生医学研究所セミナー
- Place of Presentation
  熊本大学発生医学研究所招待講演
- Year and Date
  2010-03-16
- Data Source
  KAKENHI-PROJECT-21770119
[Presentation] 翻訳後修飾を指標にしたマウス神経幹細胞の分化の運命づけを司る核内分子の探索2009
- Author(s)
  新森加納子, 他
- Organizer
  神経発生討論会
- Place of Presentation
  愛知県岡崎市(ポスター発表)
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-21770119
[Presentation] 翻訳後修飾を指標にしたマウス神経幹細胞の分化の運命づけを司る核内分子の探索2009
- Author(s)
  新森加納子, 他
- Organizer
  日本ヒトプロテオーム学会/日本ヒトプロテオーム機構第7回大会(JHUPO)
- Place of Presentation
  東京白金北里大学(ポスター発表)
- Data Source
  KAKENHI-PROJECT-21770119
[Presentation] 翻訳後修飾を指標にしたマウス神経幹細胞の分化の運命づけを司る核内分子の探索2009
- Author(s)
  新森加納子
- Organizer
  日本ヒトプロテオーム機構第7回大会
- Place of Presentation
  東京白金北里大学
- Data Source
  KAKENHI-PROJECT-21770119

1. Ito Takaaki (70168392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
2. HASEGAWA Koki (50525798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
3. 塚本善之 (00433053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 麓祥一 (00532631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 柴田智隆 (20566905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 泥谷直樹 (80305036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 守山正胤 (90239707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 永原則之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KITA KANAKO 喜多 加納子

Kanako Niimori-Kita 新森 加納子

NIIMORI Kanako 新森 加納子

Research Projects

Research Products

Co-Researchers

肺小細胞癌の悪性度を司る神経幹細胞未分化性維持因子を標的とした核酸抗癌剤の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

神経幹細胞未分化性維持因子を標的とした肺小細胞癌新規モダリティーの創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Screening of biomarkers and targets for cancer therapy by nuclear phosphoproteomics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of small cell lung cancer therapy targeting neural stem cell undifferentiation maintenance factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a small cell lung cancer treatment method being applied the disruption of its molecular basis of the neural stem cell undifferentiated maintenance factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms on genesis of combined type small cell carcinoma; a study focusing on Notch signaling

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of malignancy and immaturity in lung small cell carcinoma using a neural stem cell novel factor detected by posttranslational modification proteomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The molecular regulation of differentiation, proliferation and highly malignancy character of small cell lung cancer by proteomic analysis of post-translational modification.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of post-translational modification in nuclear proteins during neural stem cell fate specification by proteomic analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Notch1 controls cell chemo-resistance in small cell lung carcinoma cells.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] NEPA21 is usuful for elucidating malignancy and undifferentiation of cancer cells2016

Author(s)

Journal Title

Data Source

[Journal Article] Insulinoma-Associated protein 1 is a crucial regulator of neuroendocrine differentiation in lung cancer2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phosphoproteomics illuminates a new molecule in stem cell maintenance.2015

Author(s)

Journal Title

Data Source

[Journal Article] Sex differences in shotgun proteome analyses for chronic oral intake of cadmium in mice2015

Author(s)

KITA KANAKO 喜多加納子

Kanako Niimori-Kita 新森加納子

NIIMORI Kanako 新森加納子