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Yoda Masaki  依田 昌樹

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YODA MASAKI  依田 昌樹

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Researcher Number 30464994
Other IDs
Affiliation (Current) 2025: 東京慈恵会医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2024: 東京慈恵会医科大学, 医学部, 講師
2021 – 2023: 慶應義塾大学, 医学部(信濃町), 特任助教
2018 – 2019: 慶應義塾大学, 医学部(信濃町), 特任助教
2016 – 2017: 慶應義塾大学, 医学部(信濃町), 助教
2014 – 2015: 慶應義塾大学, 医学部, 助教
2011 – 2015: 慶應義塾大学, 医学部, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery / General physiology
Except Principal Investigator
Basic Section 56020:Orthopedics-related / Orthopaedic surgery
Keywords
Principal Investigator
加齢 / 筋再生 / 筋線維化 / 間葉系前駆細胞 / 筋損傷 / 発生・分化 / シグナル伝達 / シェディング / Notch / ADAM10 … More / 筋衛星細胞 / 筋拘縮 / FAPs / 遺伝子発現解析 / 筋萎縮 / 形態形成因子 / 三次元イメージング / 軟骨原基 / 軟骨分化 / 間葉系細胞 / 軟骨発生 / 3次元解析 / 組織透明化 / 軟骨形成 / 骨形成 / 細胞間相互作用 / 形態形成 / 三次元解析 / 骨・軟骨代謝学 / 細胞分化 / 破骨細胞分化 / Notchシグナル / 骨・軟骨代謝 / 免疫学 / 造血 / shedding / 骨代謝 … More
Except Principal Investigator
間葉系前駆細胞 / 骨格筋変性 / IL-33 / サルコペニア / 骨格筋萎縮 / 網羅的遺伝子解析 / 筋肥大 / 不動性筋萎縮 / 筋萎縮回復 / 筋再生 / MRI / 腱板損傷 / 筋変性 / 造血制御 / TACE/ADAM10 / 小胞体ストレス応答 / ADAM17 / ADAM10 / 骨代謝 / 小胞体ストレス / ADAM遺伝子 / 筋代謝 / 骨軟骨代謝 Less
  • Research Projects

    (9 results)
  • Research Products

    (30 results)
  • Co-Researchers

    (9 People)
  •  不動性筋萎縮回復過程における間葉系前駆細胞の機能解析および回復促進因子の探索

    • Principal Investigator
      辻 収彦
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Keio University
  •  Elucidation of the mechanism of muscle injury repair processes mediated by muscle mesenchymal progenitor cellsPrincipal Investigator

    • Principal Investigator
      依田 昌樹
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Jikei University School of Medicine
  •  骨格筋萎縮・変性における間葉系前駆細胞の機能解析

    • Principal Investigator
      堀内 圭輔
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      National Defense Medical College
  •  Elucidation of the mechanism of muscle degeneration using a mouse model and search for biomarkers of muscle regeneration using MRI

    • Principal Investigator
      Tsuji Osahiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Keio University
  •  Elucidation of the mechanism of skeletal muscle fibrosis associated with muscle injury and agingPrincipal Investigator

    • Principal Investigator
      Yoda Masaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Keio University
  •  Three-dimensional analysis of morphogenetic factors forming cartilage primordiaPrincipal Investigator

    • Principal Investigator
      YODA Masaki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General physiology
    • Research Institution
      Keio University
  •  Regulation of bone and cartilage formation by ADAM10Principal Investigator

    • Principal Investigator
      Yoda Masaki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Keio University
  •  Functional analysis of ADAMs in the musculoskeletal and hematopoietic system

    • Principal Investigator
      Horiuchi Keisuke
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Keio University
  •  Involvement in bone metabolism of Notch signaling regulated by ADAM10Principal Investigator

    • Principal Investigator
      YODA MASAKI
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Keio University

All 2024 2023 2022 2020 2019 2018 2017 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

  • [Journal Article] IL-33-ST2 signaling in fibro-adipogenic progenitors alleviates immobilization-induced muscle atrophy in mice2024

    • Author(s)
      Yoshiyuki Takahashi, Masaki Yoda, Osahiko Tsuji, Keisuke Horiuchi, Kota Watanabe, Masaya Nakamura
    • Journal Title

      Skeletal Muscle

      Volume: 14 Issue: 1 Pages: 1-11

    • DOI

      10.1186/s13395-024-00338-2

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09309
  • [Journal Article] Aging Aggravates the Progression of Muscle Degeneration After Rotator Cuff Tears in Mice2022

    • Author(s)
      Takada Yuhei、Matsumura Noboru、Shirasawa Hideyuki、Yoda Masaki、Matsumoto Morio、Nakamura Masaya、Horiuchi Keisuke
    • Journal Title

      Arthroscopy: The Journal of Arthroscopic & Related Surgery

      Volume: 38 Issue: 3 Pages: 752-760

    • DOI

      10.1016/j.arthro.2021.09.014

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09636, KAKENHI-PROJECT-20K09488, KAKENHI-PROJECT-21K09309
  • [Journal Article] ADAM10 is indispensable for longitudinal bone growth in mice2020

    • Author(s)
      Mizuno S, Yoda M, Kimura T, Shimoda M, Akiyama H, Chiba K, Nakamura M, Horiuchi K
    • Journal Title

      Bone

      Volume: 134 Pages: 115273-115273

    • DOI

      10.1016/j.bone.2020.115273

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K08548, KAKENHI-PROJECT-19K09613
  • [Journal Article] Trans-pairing between osteoclasts and osteoblasts shapes the cranial base during development.2019

    • Author(s)
      Edamoto M, Kuroda Y, Yoda M, Kawaai K, Matsuo K.
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 297-297

    • DOI

      10.1038/s41598-018-38471-w

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04015, KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-16K08506, KAKENHI-PROJECT-17K08548
  • [Journal Article] Bone2019

    • Author(s)
      Matsuo K, Ji S, Miya A, Yoda M, Hamada Y, Tanaka T, Takao-Kawabata R, Kawaai K, Kuroda Y, Shibata S.
    • Journal Title

      Innervation of the tibial epiphysis through the intercondylar foramen.

      Volume: 120 Pages: 297-304

    • DOI

      10.1016/j.bone.2018.11.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04015, KAKENHI-PROJECT-16K07075, KAKENHI-PROJECT-16K08506, KAKENHI-PROJECT-17K08548
  • [Journal Article] IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis2015

    • Author(s)
      Tohmonda T, Yoda M, Iwawaki T, Matsumoto M, Nakamura M, Mikoshiba K, Toyama Y, Horiuchi K.
    • Journal Title

      J Clin Investigation

      Volume: 125(8) Issue: 8 Pages: 3269-79

    • DOI

      10.1172/jci76765

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25221002, KAKENHI-PROJECT-24390358
  • [Journal Article] Generation and characterization of a novel shoulder contracture mouse model2015

    • Author(s)
      Oki S, Shirasawa H, Yoda M, Matsumura N, Tohmonda T, Yuasa K, Nakamura M, Matsumoto M, Horiuchi K
    • Journal Title

      Journal of Orthopeadic Research

      Volume: 33 Issue: 11 Pages: 1732-8

    • DOI

      10.1002/jor.22943

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390358
  • [Journal Article] A Disintegrin and Metalloprotease 10 (ADAM10) Is Indispensable for Maintenance of the Muscle Satellite Cell Pool2015

    • Author(s)
      Mizuno S, Yoda M, Shimoda M, Tohmonda T, Okada Y, Toyama Y, Takeda S, Nakamura M, Matsumoto M, Horiuchi K.
    • Journal Title

      Journal of Biological chemistry

      Volume: 290 Issue: 47 Pages: 28456-64

    • DOI

      10.1074/jbc.m115.653477

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390358, KAKENHI-PROJECT-25282202
  • [Journal Article] ADAM17 regulates IL-1 signaling by selectively releasing IL-1 receptor type 2 from the cell surface.2014

    • Author(s)
      Uchikawa S, Yoda M, Tohmonda T, Kanaji A, Matsumoto M, Toyama Y, Horiuchi K
    • Journal Title

      Cytokine

      Volume: 71 Issue: 2 Pages: 238-245

    • DOI

      10.1016/j.cyto.2014.10.032

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390358, KAKENHI-PROJECT-24791566
  • [Journal Article] Conditional inactivation of TNFα-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones2013

    • Author(s)
      Saito K, Horiuchi K, Kimura T, Mizuno S, Yoda M, Morioka H, Akiyama H, Threadgill D, Okada Y, Toyama Y, Sato K
    • Journal Title

      PLoS One

      Volume: 8(1) Issue: 1 Pages: e54853-e54853

    • DOI

      10.1371/journal.pone.0054853

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592230, KAKENHI-PROJECT-24249022, KAKENHI-PROJECT-24390358
  • [Journal Article] Systemic overexpression of TNFα-converting enzyme does not lead to enhanced shedding activity in vivo2013

    • Author(s)
      Yoda M, Kimura T, Tohmonda T, Morioka H, Matsumoto M, Okada Y, Toyama Y, Horiuchi K
    • Journal Title

      PLoS One

      Volume: 8(1) Issue: 1 Pages: e54412-e54412

    • DOI

      10.1371/journal.pone.0054412

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592230, KAKENHI-PROJECT-24249022, KAKENHI-PROJECT-24390358
  • [Journal Article] Dual functions of cell-autonomous and non-cell-autonomous ADAM10 activity in granulopoiesis2011

    • Author(s)
      Yoda M, Kimura T, Tohmonda T, Uchikawa S, Koba T, Takito J, Morioka H, Matsumoto M, Link DC, Chiba K, Okada Y, Toyama Y, Horiuchi K
    • Journal Title

      Blood

      Volume: 118(26) Issue: 26 Pages: 6939-42

    • DOI

      10.1182/blood-2011-06-357210

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592230
  • [Presentation] The IL-33-ST2 Signaling in Fibro-adipogenic Progenitors Attenuates Immobilization-induced Muscle Atrophy2024

    • Author(s)
      Yoshiyuki Takahashi, Masaki Yoda, Osahiko Tsuji, Keisuke Horiuchi, Kota Watanabe, Masaya Nakamura
    • Organizer
      Orthopaedic Research Society Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K09309
  • [Presentation] 廃用性筋萎縮における骨格筋間葉系前駆細胞の機能解析2023

    • Author(s)
      高橋慶行、依田昌樹、辻収彦、堀内圭輔、渡辺航太、中村雅也
    • Organizer
      第9回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09213
  • [Presentation] 廃用性筋萎縮における骨格筋間葉系前駆細胞の機能解析2023

    • Author(s)
      高橋慶行,依田昌樹,辻収彦,堀内圭輔,渡辺航太,中村雅也
    • Organizer
      日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09309
  • [Presentation] 筋損傷後の筋再生における間葉系前駆細胞の役割2023

    • Author(s)
      依田昌樹,高橋慶行,東門田誠一,今村美佳,辻収彦,中村雅也
    • Organizer
      日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09309
  • [Presentation] 廃用性筋萎縮における骨格筋間葉系前駆細胞の機能解析2022

    • Author(s)
      高橋慶行、依田昌樹、辻収彦、堀内圭輔、渡辺航太、中村雅也
    • Organizer
      第8回日本筋学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K09213
  • [Presentation] 廃用性筋萎縮における骨格筋間葉系前駆細胞の機能解析2022

    • Author(s)
      高橋慶行、依田昌樹、辻収彦、堀内圭輔、渡辺航太、中村雅也
    • Organizer
      第37回日本整形外科学科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-21K09213
  • [Presentation] 腱板断裂における腱板構成筋変性機序の評価2022

    • Author(s)
      瀬戸貴之、辻収彦、松村昇、中村匠、前田康介、高橋慶行、依田昌樹、堀内圭輔、中村雅也
    • Organizer
      第37回日本整形外科学科基礎学術集会
    • Data Source
      KAKENHI-PROJECT-21K09213
  • [Presentation] マウス腓骨における骨形成部位は成長に伴い変化する2018

    • Author(s)
      依田昌樹・黒田有希子・松尾光一
    • Organizer
      第36回日本骨代謝学会学術集会
    • Data Source
      KAKENHI-PROJECT-17K08548
  • [Presentation] Bone Renovation of the Mouse Neonatal Fibula into the Adult Skeleton2017

    • Author(s)
      Masaki Yoda, Yukiko Kuroda, Koichi Matsuo
    • Organizer
      The American Society for Bone and Mineral Research, Denver, CO, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08548
  • [Presentation] マウス腓骨における内軟骨性骨化後の断面形状の改変2017

    • Author(s)
      依田昌樹、黒田有希子、松尾光一
    • Organizer
      第35回日本骨代謝学会学術集会(福岡県福岡市)
    • Data Source
      KAKENHI-PROJECT-17K08548
  • [Presentation] ADAM10-Notchシグナル伝達を介した骨髄系細胞分化はG-CSF依存的および非依存的な経路によって制御されている2012

    • Author(s)
      依田昌樹,戸山芳昭,堀内圭輔
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Data Source
      KAKENHI-PROJECT-23592230
  • [Presentation] ADAM10-Notchシグナル伝達を介した骨髄系細胞分化はG-CSF依存的および非依存的な経路によって制御されている2012

    • Author(s)
      依田昌樹
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡
    • Year and Date
      2012-12-14
    • Data Source
      KAKENHI-PROJECT-24390358
  • [Presentation] ADAM10-Notch signaling regulates granulopoiesis via G-CSF-dependent and -independent manners2012

    • Author(s)
      Masaki Yoda, Yoshiaki Toyama, Keisuke Horiuchi
    • Organizer
      第35回 日本分子生物学会
    • Place of Presentation
      福岡国際会議場、マリンメッセ福岡
    • Data Source
      KAKENHI-PROJECT-23592230
  • [Presentation] 破骨細胞分化におけるIRE1α-XBP1経路の機能解析

    • Author(s)
      東門田 誠一, 依田 昌樹, 松本 守雄, 戸山 芳昭, 堀内 圭輔
    • Organizer
      第32回日本骨代謝学会学
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-24 – 2014-07-26
    • Data Source
      KAKENHI-PROJECT-24390358
  • [Presentation] 軟骨特異的なADAM10-Notchシグナルの抑制は顕著な成長障害を来たす

    • Author(s)
      依田昌樹,水野早希子,秋山治彦,松本守雄,戸山芳昭,堀内圭輔
    • Organizer
      第32回日本骨代謝学会学術集会
    • Place of Presentation
      大阪
    • Year and Date
      2014-07-24 – 2014-07-26
    • Data Source
      KAKENHI-PROJECT-26462318
  • [Presentation] 軟骨細胞におけるADAM10-Notchシグナルの抑制は顕著な成長障害を来たす

    • Author(s)
      依田昌樹,水野早希子,秋山治彦,戸山芳昭,松本守雄,堀内圭輔
    • Organizer
      第28回日本軟骨代謝学会
    • Place of Presentation
      東京
    • Year and Date
      2015-03-06 – 2015-03-07
    • Data Source
      KAKENHI-PROJECT-26462318
  • [Presentation] 不良タンパク質応答に機能するIRE1α-XBP1経路は新規の破骨細胞分化誘導因子である

    • Author(s)
      堀内 圭輔, 東門田 誠一, 依田 昌樹, 松本 守雄, 戸山 芳昭
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09 – 2014-10-10
    • Invited
    • Data Source
      KAKENHI-PROJECT-24390358
  • [Presentation] マウスを利用した新規肩関節拘縮モデルの作成およびその分子生物学的評価

    • Author(s)
      大木 聡, 依田 昌樹, 木場 健, 東門田 誠一, 松村 昇, 戸山 芳昭, 堀内 圭輔
    • Organizer
      第29回日本整形外科学会基礎学術集会
    • Place of Presentation
      鹿児島
    • Year and Date
      2014-10-09 – 2014-10-10
    • Data Source
      KAKENHI-PROJECT-24390358
  • 1.  HORIUCHI Keisuke (30327564)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 14 results
  • 2.  Tsuji Osahiko (70424166)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 3.  TOHMONDA Takahide (40415237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 4.  TOYAMA Yoshiaki (40129549)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  畑 純一 (00568868)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  藤吉 兼浩 (80365303)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  KURODA Yukiko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 8.  松尾 光一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 9.  御子柴 克彦
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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