sunagawa youichi 砂川陽一

… Alternative Names

Sunagawa Yoichi 砂川陽一

SUNAGAWA YOICHI 砂川陽一

SUNAGAWA Yoichi 砂川陽一

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Researcher Number	30466297
Other IDs
Affiliation (Current)	2025: 静岡県立大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 静岡県立大学, 薬学部, 講師 2019 – 2020: 静岡県立大学, 薬学部, 助教 2015 – 2017: 静岡県立大学, 薬学部, 助教 2013: 静岡県立大学, 薬学部, その他 2013: 静岡県立大学, 薬学部, 客員研究員 2012: 静岡県立大学, 薬学部, 研究支援員
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 47050:Environmental and natural pharmaceutical resources-related / Cardiovascular medicine / Biological pharmacy Except Principal Investigator Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator p300 / GATA4 / 心肥大 / アセチル化 / 転写因子 / p300 binding proteins / heart failure / fibrosis / cardiac hypertrophy / 心筋肥大 … More / アセチル化活性 / 心不全 / ノビレチン / NBP1 / 二量体 / 結晶構造解析 / 二量体化 / 二量体形成 / 心肥大反応 / RbAp46 / RbAp48 / 翻訳後修飾 … More Except Principal Investigator 心筋細胞肥大 / 心不全 / 治療薬 / 多量体形成 / 心肥大 / ノックインマウス / ホモ多量体化 / GATA4 / ヒストンアセチル化 / プロテオミクス / ｐ３００ / 心臓特異的ノックアウトマウス / 心臓リモデリング / 結合タンパク / 心臓線維化 / 病態プロオミクス / ヒストンアセチルトランスフェラーゼ / エピジェネティクス / p300 Less

The studyon of p300 complex on cardiac hypertrophy and fibrosis during the development of heart failurePrincipal Investigator
- Principal Investigator
  
  砂川陽一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  University of Shizuoka
ノックインマウスを用いた心不全によるGATA4多量体形成の変化並びに治療薬の探索研究
- Principal Investigator
  
  森本達也
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  University of Shizuoka
Identification and functional analysis of p300 regulatory factors involved in the development of heart failure using medical proteomics
- Principal Investigator
  
  Morimoto Tatsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  University of Shizuoka
The study of functional mechanism of Nobiletin, which possess the therapeutic potency for development of heart failure.Principal Investigator
- Principal Investigator
  
  Sunagawa Yoichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  University of Shizuoka
Analysis of GATA4 dimarization during hypertrophic responsesPrincipal Investigator
- Principal Investigator
  
  SUNAGAWA YOICHI
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  University of Shizuoka
Analysis of novel p300/GATA4 binding complex druing cardiomyocyte hypertrophy by proteomics approachPrincipal Investigator
- Principal Investigator
  
  SUNAGAWA Yoichi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  University of Shizuoka

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation Book

[Book] 細胞内シグナル伝達異常と心不全、臨床心不全の基礎知識2014
- Author(s)
  砂川陽一、刀坂泰史、森本達也、長谷川浩二
- Data Source
  KAKENHI-PROJECT-24890191
[Book] 心臓の老化とクルクミン治療、Heart View2013
- Author(s)
  森本達也、砂川陽一、刀坂泰史、鈴木秀敏、和田啓道、長谷川浩二、;
- Data Source
  KAKENHI-PROJECT-24890191
[Book] 心不全薬物療法:現状と今後、J-ISCP会誌心血管薬物療法2013
- Author(s)
  森本達也、鈴木秀敏、砂川陽一、刀坂泰史、和田啓道、長谷川浩二
- Data Source
  KAKENHI-PROJECT-24890191
[Book] 甲状腺ホルモン/心不全を中心とした循環器への影響、日本甲状腺学会雑誌2012
- Author(s)
  森本達也、鈴木秀敏、砂川陽一、刀坂泰史、和田啓道、長谷川浩二
- Data Source
  KAKENHI-PROJECT-24890191
[Journal Article] Anserine, a Histidine-Containing Dipeptide, Suppresses Pressure Overload-Induced Systolic Dysfunction by Inhibiting Histone Acetyltransferase Activity of p300 in Mice2024
- Author(s)
  Sunagawa Yoichi、Tsukabe Ryosuke、Irokawa Yudai、Funamoto Masafumi、Suzuki Yuto、Yamada Miho、Shimizu Satoshi、Katanasaka Yasufumi、Hamabe-Horiike Toshihide、Kawase Yuto、Naruta Ryuya、Shimizu Kana、Mori Kiyoshi、Hosomi Ryota、Komiyama Maki、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 4 Pages: 2344-2344
- DOI
  10.3390/ijms25042344
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16106, KAKENHI-PROJECT-23K06098, KAKENHI-PROJECT-21K08069
[Journal Article] Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice2024
- Author(s)
  Katanasaka Yasufumi、Yabe Harumi、Murata Noriyuki、Sobukawa Minori、Sugiyama Yuga、Sato Hikaru、Honda Hiroki、Sunagawa Yoichi、Funamoto Masafumi、Shimizu Satoshi、Shimizu Kana、Hamabe-Horiike Toshihide、Hawke Philip、Komiyama Maki、Mori Kiyoshi、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nature Communications
  
  Volume: 15 Issue: 1 Pages: 2344-2344
- DOI
  10.1038/s41467-024-46711-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16106, KAKENHI-PROJECT-23K06098
[Journal Article] 6-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure2023
- Author(s)
  Kawase Yuto、Sunagawa Yoichi、Shimizu Kana、Funamoto Masafumi、Hamabe-Horiike Toshihide、Katanasaka Yasufumi、Shimizu Satoshi、Hawke Philip、Mori Kiyoshi、Komiyama Maki、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nutrients
  
  Volume: 15 Issue: 9 Pages: 2232-2232
- DOI
  10.3390/nu15092232
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16106, KAKENHI-PROJECT-23K06098, KAKENHI-PROJECT-21K08069
[Journal Article] Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response2022
- Author(s)
  Shimizu Satoshi、Sunagawa Yoichi、Hajika Naruto、Yorimitsu Natsumi、Katanasaka Yasufumi、Funamoto Masafumi、Miyazaki Yusuke、Sari Nurmila、Shimizu Kana、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  International Journal of Biological Sciences
  
  Volume: 18 Issue: 3 Pages: 1079-1095
- DOI
  10.7150/ijbs.65664
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396, KAKENHI-PROJECT-21K08069
[Journal Article] The Polyunsaturated Fatty Acids, EPA and DHA, Ameliorate Myocardial Infarction-induced Heart Failure by Inhibiting p300-HAT Activity in Rats2022
- Author(s)
  Sunagawa Yoichi、Katayama Ayumi、Funamoto Masafumi、Shimizu Kana、Shimizu Satoshi、Nurmila Sari、Katanasaka Yasufumi、Miyazaki Yusuke、Hosomi Ryota、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  The Journal of Nutritional Biochemistry
  
  Volume: 106 Pages: 109031-109031
- DOI
  10.1016/j.jnutbio.2022.109031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396, KAKENHI-PROJECT-21K08069
[Journal Article] Ecklonia stolonifera Okamura Extract Suppresses Myocardial Infarction-Induced Left Ventricular Systolic Dysfunction by Inhibiting p300-HAT Activity2022
- Author(s)
  Katagiri Takahiro、Sunagawa Yoichi、Maekawa Tatsuya、Funamoto Masafumi、Shimizu Satoshi、Shimizu Kana、Katanasaka Yasufumi、Komiyama Maki、Hawke Philip、Hara Hideo、Mori Kiyoshi、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 3 Pages: 580-580
- DOI
  10.3390/nu14030580
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396, KAKENHI-PROJECT-21K08069
[Journal Article] Chrysanthemum morifolium Extract Ameliorates Doxorubicin-Induced Cardiotoxicity by Decreasing Apoptosis2022
- Author(s)
  Ono Masaya、Sunagawa Yoichi、Mochizuki Saho、Katagiri Takahiro、Takai Hidemichi、Iwashimizu Sonoka、Inai Kyoko、Funamoto Masafumi、Shimizu Kana、Shimizu Satoshi、Katanasaka Yasufumi、Komiyama Maki、Hawke Philip、Hara Hideo、Arakawa Yoshiki、Mori Kiyoshi、Asai Akira、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 3 Pages: 683-683
- DOI
  10.3390/cancers14030683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396
[Journal Article] Curcumin, an Inhibitor of p300-HAT Activity, Suppresses the Development of Hypertension-Induced Left Ventricular Hypertrophy with Preserved Ejection Fraction in Dahl Rats2021
- Author(s)
  Sunagawa Yoichi、Funamoto Masafumi、Shimizu Kana、Shimizu Satoshi、Sari Nurmila、Katanasaka Yasufumi、Miyazaki Yusuke、Kakeya Hideaki、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 8 Pages: 2608-2608
- DOI
  10.3390/nu13082608
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396, KAKENHI-PLANNED-17H06401, KAKENHI-PROJECT-21K08069
[Journal Article] The Selective Serotonin 2A Receptor Antagonist Sarpogrelate Prevents Cardiac Hypertrophy and Systolic Dysfunction via Inhibition of the ERK1/2?GATA4 Signaling Pathway2021
- Author(s)
  Shimizu Kana、Sunagawa Yoichi、Funamoto Masafumi、Honda Hiroki、Katanasaka Yasufumi、Murai Noriyuki、Kawase Yuto、Hirako Yuta、Katagiri Takahiro、Yabe Harumi、Shimizu Satoshi、Sari Nurmila、Wada Hiromichi、Hasegawa Koji、Morimoto Tatsuya
- Journal Title
  
  Pharmaceuticals
  
  Volume: 14 Issue: 12 Pages: 1268-1268
- DOI
  10.3390/ph14121268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16396
[Journal Article]2013
- Author(s)
  Morimoto T, Sunagawa Y, Katanasaka Y, Hirano S, Namiki M, Watanabe Y, Suzuki H, Doi O, Suzuki K, Yamauchi M, Yokoji T, Miyoshi-Morimoto E, Otsuka Y, Hamada T, Imaizumi A, Nonaka Y, Fuwa T, Teramoto T, Kakeya H, Wada H, Hasegawa K
- Journal Title
  
  Biol Pharm Bull
  
  Volume: 96 Pages: 1708-1714
- Data Source
  KAKENHI-PROJECT-24890191
[Journal Article] Application of Curcumin to Heart Failure Therapy by Targeting Transcriptional Pathway in Cardiomyocytes2013
- Author(s)
  Yoichi Sunagawa
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 36 Issue: 1 Pages: 13-17
- DOI
  10.1248/bpb.b212022
- NAID
  130003361361
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] A Novel p300 Binding Protein 1 is Required for Pressure-overload Induced Cardiac Hypertrophy and Dysfunction in Mice2024
- Author(s)
  Sunagawa Y, Ishima A, Suzuki Y, Hamabe-Horiike H, Katanasaka Y, Hasegawa K, Morimoto T
- Organizer
  第88回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06098
[Presentation] A novel p300 binding protein 1 is required for hypertrophic and fibrotic responses in cardiomyocytes and cardiofibroblasts2023
- Author(s)
  Yoichi Sunagawa
- Organizer
  第87回日本循環器学会学術集会（
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 転写因子GATA4の多量体形成阻害は心筋細胞肥大を抑制した2023
- Author(s)
  須藤優、塚部凌輔、川瀬裕斗、清水聡史、浜辺俊秀、砂川陽一、船本雅文、清水果奈、刀坂泰史、長谷川浩二、森本達也
- Organizer
  第148回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] Multimerization of GATA4 is required for hypertrophic responses in cultured cardiomyocytes2023
- Author(s)
  Ryosuke Tsukabe, Satoshi Shimizu, Yoichi Sunagawa, Yasufumi Katanasaka, Toshihide Hamabe-Horiike, Masafumi Funamoto, Kana Shimizu, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 34th Great Wall International Congress of Cardiology (GW-ICC) & Asian Heart Society Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] 転写因子GATA4の多量体形成阻害はフェニレフリン誘導性の心筋細胞肥大を抑制した2023
- Author(s)
  須藤優、塚部凌輔、川瀬裕斗、清水聡史、浜辺俊秀、砂川陽一、船本雅文、清水果奈、刀坂泰史、長谷川浩二、森本達也
- Organizer
  第27回日本統合医療学会学術大会
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] Multimerization of GATA4 is required for hypertrophic responses in cultured cardiomyocytes2023
- Author(s)
  Ryosuke Tsukabe, Satoshi Shimizu, Yoishi Sunagawa, Yasufumi Katanasaka, Toshihide Hamabe, Masafumi Funamoto, Kana Shimizu, Maki Komiyama, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第27回日本心不全学会
- Data Source
  KAKENHI-PROJECT-23K06153
[Presentation] Identification Of Novel p300 Binding Proteins, Which are Involved In Cardiomyocyte Hypertrophy2022
- Author(s)
  Yoichi Sunagawa
- Organizer
  第85回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] Nobiletin Binding Protein 1 is Required to Exhibit Therapeutic Potency of Nobiletin for Heart Failure through inhibition of p300 activity2021
- Author(s)
  砂川陽一
- Organizer
  第85回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] カンキツ由来化合物ノビレチンはp300-HAT活性制御を介して心不全進展を抑制する2021
- Author(s)
  砂川陽一
- Organizer
  第21回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] Identification of Novel p300 Binding Proteins, which Are Involved in Cardiomyocyte Hypertrophy2020
- Author(s)
  Yoichi Sunagawa, Yusaku, Matsushita, Mizuki Unno, Sho Uehara, Masafumi Funamoto, Kana Shimizu, Satoshi Shimizu, Sari Nurmila, Yusuke Miyazaki, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第85回日本循環器学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 新規p300結合タンパク質であるp300-binding protein 1は培養心筋細胞において肥大反応を促進した2020
- Author(s)
  海野瑞紀、砂川陽一、松下優作、船本雅文、清水果奈、清水聡史、刀坂泰史、宮崎雄輔、長谷川浩二、森本達也
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] BPK1, a novel p300-binding protein, regulated p300-mediated hypertrophic response in cultured cardiomyocytes2020
- Author(s)
  Mizuki Unno, Yusaku Matsushita, Yoichi Sunagawa , Masafumi Funamoto , Kana Shimizu , Satoshi Shimizu , Nurmila Sari , Yasufumi Katanasaka , Yusuke Miyazaki , Hiromichi Wada , Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第25回静岡健康・長寿学術フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] p300結合タンパク質であるSTK39のノックダウンは心筋細胞の肥大を誘発する2020
- Author(s)
  海野瑞紀、松下優作、砂川陽一、船本雅文、清水果奈、Nurmila Sari、清水聡史、宮﨑雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] Analysis of a novel p300 binding protein in the regulation of cardiomyocyte hypertrophy2020
- Author(s)
  Yusaku Matsushita, Yoichi Sunagawa, Mizuki Unno, Masafumi Funamoto, Kana Smizu, Satoshi Shimizu, Nurmila Sari, Yasufumi Kataka, Yusuke Miyazaki, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第4回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] A novel p300 binding protein regulates cardiomyocyte hypertrophy2020
- Author(s)
  Yusaku Matsushita, Yoichi Sunagawa, Mizuki Unno, Masafumi Funamoto, Kana Smizu, Satoshi Shimizu, Nurmila Sari, Yasufumi Kataka, Yusuke Miyazaki, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第25回静岡健康・長寿学術フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 新規Nobiletin標的因子 (NBP1) はp300/GATA4経路を介して心筋細胞肥大を抑制する2020
- Author(s)
  江部綾香、砂川陽一、内藤汐美、長谷川浩二、森本達也
- Organizer
  日本薬学会第139回年会
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] 遺伝子改変マウスを用いた心臓特異的なp300結合タンパク質の同定及び機能解析2020
- Author(s)
  松下優作、砂川陽一、海野瑞紀、船本雅文、清水果奈、清水聡史、サリヌーミラ、刀坂泰史、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2020
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] p300結合因子のSTK39はノックダウンにより培養心筋細胞の肥大反応を誘発した2020
- Author(s)
  海野瑞紀、松下優作、砂川陽一、船本雅文、清水果奈、Nurmila Sari、清水聡史、宮﨑雄輔、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  第143回　日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 新規p300結合タンパク質であるBP1は心筋細胞肥大を促進した2020
- Author(s)
  松下優作、砂川陽一、海野瑞紀、船本雅文、清水果奈、清水聡史、サリヌーミラ、刀坂泰史、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  第143回　日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] 新規Nobiletin標的因子であるNBP1はp300の翻訳後修飾を介して心筋細胞肥大を抑制した2020
- Author(s)
  高井秀通、砂川陽一、内藤汐美、長谷川浩二、森本達也
- Organizer
  第143回　日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] 心不全発症に関与する新規p300結合タンパク質の同定及び機能解析2020
- Author(s)
  松下優作、砂川陽一、海野瑞紀、船本雅文、清水果奈、清水聡史、サリヌーミラ、刀坂泰史、宮崎雄輔、和田啓道、長谷川浩二、森本達也
- Organizer
  第20回抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-20K07070
[Presentation] ノビレチン結合因子であるNBP1はノビレチンの心不全進展抑制作用の発揮に必要である2020
- Author(s)
  高井秀通、砂川陽一、内藤汐美、長谷川浩二、森本達也
- Organizer
  第4回ノビレチン研究会
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] 柑橘系果皮由来ポリメトキシフラボノイドであるノビレチンの心不全進行抑制効果及びその作用機序の解明2019
- Author(s)
  砂川陽一
- Organizer
  第19回日本抗加齢医学会総会
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] ポリメトキシフラボノイドであるノビレチンの心不全進行抑制及びその作用機序の解明2019
- Author(s)
  砂川陽一
- Organizer
  第3回ノビレチン研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16396
[Presentation] 心肥大応答を司る転写因子GATA4の二量体形成・DNA結合部位の同定と結晶化2018
- Author(s)
  清水聡史, 原幸大, 砂川陽一, 菱木麻美, 宮崎雄輔, 刀坂泰史, 船本雅文, Nurmila Sari, 清水果奈, 和田啓道, 長谷川浩二, 橋本博, 森本達也
- Organizer
  日本薬学会第138年会,
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Dimerization domain of GATA4, a hypertrophy-responsive transcription factor is the therapeutic targets2018
- Author(s)
  Shimizu S., Hara K, Sunagawa Y, Hishiki A, Funamoto M, Miyazaki Y, Katanasaka Y, Wada H, Hasegawa K, Hashimoto H, Morimoto T
- Organizer
  第1回日本循環器学会基礎研究フォーラム
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] The dimerization domain of the hypertrophy-responsive transcription factor GATA4 is a therapeutic target for heart failure2018
- Author(s)
  Shimizu S., Hara K, Sunagawa Y, Hishiki A, Funamoto M, Miyazaki Y, Katanasaka Y, Wada H, Hasegawa K, Hashimoto H, Morimoto T
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Determination and crystallization of GATA4 dimerization domain spectrometry.2018
- Author(s)
  Shimizu S, Hara K, Sunagawa Y, Hishiki A, Miyazaki Y, Katanasaka Y, Funamoto M, Sari N, Shimizu K, Wada H, Hasegawa K, Hashimoto H, Morimoto T.
- Organizer
  IUBMB Focused Meeting on GATA Transcription Factors,
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] The Dimerization of GATA4 is Involved in Hypertrophic Responses in Cardiomyocytes2018
- Author(s)
  ○Shimizu S, Yorimitsu N, Sunagawa Y, Katanasaka Y, Miyazaki Y, Funamoto M, Wada H, Hasegawa K, Morimoto T
- Organizer
  Asian Pacific Society of Cardiology Congress 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] 心肥大反応に関わるGATA4のZF部位のX線結晶構造解析2017
- Author(s)
  清水聡史、原幸大、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、森本達也
- Organizer
  日本薬学会第137回年会
- Place of Presentation
  東北大学他
- Year and Date
  2017-03-24
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] The dimerization domain of GATA4 is involved in the activation of hypertrophic response2017
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第81回日本循環器学会学術集会
- Place of Presentation
  石川県立音楽堂他
- Year and Date
  2017-03-17
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] 心不全に関わる転写因子GATA4の結晶構造解析2017
- Author(s)
  清水聡史、原幸大、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、橋本博、森本達也
- Organizer
  量子ビームサイエンスフェスタ
- Place of Presentation
  つくば国際会議場
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Acetylated form of GATA4 is required for GATA4 homo-dimerization2016
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第21回静岡健康長寿学術フォーラム
- Place of Presentation
  グランシップ静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Homo-dimerization of GATA4 is formed through C-terminal zinc finger domain2016
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  International Society of Cardiomyopathies and Heart Failure 2016
- Place of Presentation
  京都国際会館
- Year and Date
  2016-12-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] 心筋細胞肥大に関与する転写因子GATA4はZincフィンガードメインで直接結合し、ホモ二量体を形成する2016
- Author(s)
  清水聡史、依光奈津美、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、橋本博、森本達也
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2017
- Place of Presentation
  阿波観光ホテル
- Year and Date
  2016-06-25
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] 心肥大反応を司る転写因子GATA4の二量体はC末のZFドメインで形成される2016
- Author(s)
  依光奈津美、清水聡史、砂川陽一、刀坂泰史、和田啓道、長谷川浩二、橋本博、森本達也
- Organizer
  日本病院薬剤師会東海ブロック日本薬学会東海支部合同学術大会2017
- Place of Presentation
  長良川国際会議場
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Homo-dimarization domain of GATA4 involved in p300/GATA4-dependent hypertrophic gene activations2016
- Author(s)
  Natsumi Yorimitsu, Satoshi Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  第21回静岡健康長寿学術フォーラム
- Place of Presentation
  グランシップ静岡
- Year and Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Overexpression of GATA4 dimerization domain inhibited p300/GATA4-dependent hypertrophic genes transcription2016
- Author(s)
  Natsumi Yorimitsu, Satoshi Shimizu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 3rd International Conference on Pharma-Food (ICPF 2016)
- Place of Presentation
  日本平ホテル
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] Acetylation of GATA4 is required for the formation of GATA4 Homo-dimerization2016
- Author(s)
  Satoshi Shimizu, Natsumi Yorimitsu, Yoichi Sunagawa, Masafumi Funamoto, Yasufumi Katanasaka, Hiromichi Wada, Koji Hasegawa, Tatsuya Morimoto
- Organizer
  The 3rd International Conference on Pharma-Food (ICPF 2016)
- Place of Presentation
  日本平ホテル
- Year and Date
  2016-11-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] 心臓特異的転写因子GATA4の二量体化部位の同定とアセチル化の意義の解明2015
- Author(s)
  依光奈津美、砂川陽一、羽鹿成人、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  日本病院薬剤師会東海ブロック・日本薬学会東海支部合同学術大会2015
- Place of Presentation
  愛知
- Year and Date
  2015-11-01
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] 心臓特異的転写因子GATA4の二量体化部位の同定とアセチル化の意義について2015
- Author(s)
  依光奈津美、砂川陽一、羽鹿成人、刀坂泰史、和田啓道、島津章、長谷川浩二、森本達也
- Organizer
  第1回J-ISCP学術集会
- Place of Presentation
  京都
- Year and Date
  2015-06-20
- Data Source
  KAKENHI-PROJECT-15K21279
[Presentation] MEK-1-dependent phosphorylation of GATA4 Relieves Repressor Function of Novel GATA4 Binding Proteins, RbAp48/46, during Cardiomyocyte Hypertrophy2014
- Author(s)
  Yoichi Sunagawa
- Organizer
  第78回日本循環器学会学術集会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] MEK-1-dependent phosphorylation of GATA4 Relieves Repressor Function of Novel GATA4 Binding Proteins, RbAp48/46, during Cardiomyocyte Hypertrophy2014
- Author(s)
  Sunagawa Y
- Organizer
  第78回日本循環器学会学術集会
- Year and Date
  2014-03-23
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] RbAp48/46 Inhibit GATA 4-Dependent Hypertrophic Gene Transcription By Forming A Co-repressor Complex With HDAC/2 In Cardiomyocytes2013
- Author(s)
  Sunagawa Y
- Organizer
  Asian Pacific Society of Cardiology 2013
- Place of Presentation
  Pattaya, Thai
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] 新規セラクルミン配合飲料は既存のクルクミン飲料よりも高い吸収効率を示した2013
- Author(s)
  砂川陽一
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台・東北大学キャンパス
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] Auraptene, a Citrus Flavonoid, Prevents the Worsening of Systolic Function Following Myocardial Infarction in Rats2013
- Author(s)
  Yoichi Sunagawa
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  アメリカ、ダラス
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] Novel GATA4 Binding Proteins, RbAp48/46 Involved in Modulating Post-Translational Modification Crosstalk during Hypertrophic Responses in Cardiomyocytes2013
- Author(s)
  Yoichi Sunagawa
- Organizer
  American Heart Association Scientific Sessions 2013
- Place of Presentation
  アメリカ、ダラス
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] RbAp48/46 Inhibit GATA4-Dependent Hypertrophic Gene Transcription By Forming A Co-repressor Complex With HDAC/2 In Cardiomyocytes2013
- Author(s)
  Yoichi Sunagawa
- Organizer
  Asian Pacific Society of Cardiology 2013 Congress
- Place of Presentation
  タイ・パタヤ
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] RbAp48/46 form a Co-repressor Complex with HDAC1/2 and inhibit p300/GATA4-dependet Hypertrophic Responses in Cardiomyocytes2013
- Author(s)
  Sunagawa Y
- Organizer
  第77回日本循環器学会学術集会
- Year and Date
  2013-03-17
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] Proteomics Analysis identifies Novel Binding Targets of a Citrus Flavonoid, Nobiletin, a Potent Therapeutic Agent against Heart Failure2013
- Author(s)
  Yoichi Sunagawa
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] A Citrus Flavonoids, Nobiletin, Improves The Deterioration Of Systolic Function After Myocardial Infarction In Rats2013
- Author(s)
  Yoichi Sunagawa
- Organizer
  Asian Pacific Society of Cardiology 2013 Congress
- Place of Presentation
  タイ・パタヤ
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] Novel GATA4 Binding Proteins, RbAp48/46 Involved in Modulating Post-Translational Modification Crosstalk during Hypertrophic Responses in Cardiomyocytes2013
- Author(s)
  Sunagawa Y
- Organizer
  American Heart Association Scientific Sessions2013
- Place of Presentation
  Dallas, USA
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] RbAp48/46 form a Co-repressor Complex with HDAC1/2 and inhibit p300/GATA4-dependet Hypertrophic Responses in Cardiomyocytes2013
- Author(s)
  Yoichi Sunagawa
- Organizer
  第77回日本循環器学会学術集会
- Place of Presentation
  横浜・パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] 高吸収性クルクミンであるセラクルミン配合飲料は既存クルクミン飲料よりも高い吸収効率を示した2013
- Author(s)
  砂川陽一
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] 心不全治療薬候補である天然物Nobiletinの標的分子の同定2013
- Author(s)
  砂川陽一
- Organizer
  第13回日本抗加齢医学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] リプレッサー複合体RbAp48/46によるp300/GATA4転写複合体の翻訳後調節機構の解析2013
- Author(s)
  砂川陽一
- Organizer
  第13回京滋ハートセミナー
- Year and Date
  2013-05-09
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] Retinoblastoma Protein (Rb)-associated Protein 48 and 46, Novel p300/GATA4-binding Partners, Inhibits Hypertrophic Responses in Cardiomyocytes.2012
- Author(s)
  Yoichi Sunagawa
- Organizer
  American Heart Association Scientific Sessions 2012
- Place of Presentation
  Los Angeles, USA
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] G-CSF and erythropoietin additionally improve left ventricular systolic function in heart failure after myocardial infarction in rats.2012
- Author(s)
  Yoichi Sunagawa
- Organizer
  The 1st International Conference on Pharma-Food
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] Retinoblastoma protein (Rb)-associated protein 48 and 46 are novel components of p300/GATA4 complex and repress hypertrophic responses in cardiomyocytes2012
- Author(s)
  Sunagawa Y
- Organizer
  World Congress of Cardiology Scientific Sessions 2012
- Place of Presentation
  Dubai, UAE
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] RbAp48 and 46 Disassociate GATA4 from p300 and Inhibit Hypertrophy responsive Gene Transcription in Cardiomyocytes2012
- Author(s)
  Yoichi Sunagawa
- Organizer
  第16回日本心不全学会学術集会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24890191
[Presentation] RbAp48 and 46 disassociate GATA4 from p300 and inhibit hypertrophy-responsive gene transcription in cardiomyocytes2012
- Author(s)
  Sunagawa Y
- Organizer
  第13回日本心不全学会
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-24890191

1. Morimoto Tatsuya (50390779)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
2. 浜辺俊秀 (90963314)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 宮崎雄輔 (40803466)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
4. 船本雅文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

sunagawa youichi 砂川 陽一

Sunagawa Yoichi 砂川 陽一

SUNAGAWA YOICHI 砂川 陽一

SUNAGAWA Yoichi 砂川 陽一

Research Projects

Research Products

Co-Researchers

The studyon of p300 complex on cardiac hypertrophy and fibrosis during the development of heart failurePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ノックインマウスを用いた心不全によるGATA4多量体形成の変化並びに治療薬の探索研究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analysis of p300 regulatory factors involved in the development of heart failure using medical proteomics

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of functional mechanism of Nobiletin, which possess the therapeutic potency for development of heart failure.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of GATA4 dimarization during hypertrophic responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of novel p300/GATA4 binding complex druing cardiomyocyte hypertrophy by proteomics approachPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 細胞内シグナル伝達異常と心不全、臨床心不全の基礎知識2014

Author(s)

Data Source

[Book] 心臓の老化とクルクミン治療、Heart View2013

Author(s)

Data Source

[Book] 心不全薬物療法:現状と今後、J-ISCP会誌心血管薬物療法2013

Author(s)

Data Source

[Book] 甲状腺ホルモン/心不全を中心とした循環器への影響、日本甲状腺学会雑誌2012

Author(s)

Data Source

[Journal Article] Anserine, a Histidine-Containing Dipeptide, Suppresses Pressure Overload-Induced Systolic Dysfunction by Inhibiting Histone Acetyltransferase Activity of p300 in Mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibroblast-specific PRMT5 deficiency suppresses cardiac fibrosis and left ventricular dysfunction in male mice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 6-Shogaol, an Active Component of Ginger, Inhibits p300 Histone Acetyltransferase Activity and Attenuates the Development of Pressure-Overload-Induced Heart Failure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multimerization of the GATA4 transcription factor regulates transcriptional activity and cardiomyocyte hypertrophic response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Polyunsaturated Fatty Acids, EPA and DHA, Ameliorate Myocardial Infarction-induced Heart Failure by Inhibiting p300-HAT Activity in Rats2022

Author(s)

Journal Title

DOI

Data Source

sunagawa youichi 砂川陽一

Sunagawa Yoichi 砂川陽一

SUNAGAWA YOICHI 砂川陽一

SUNAGAWA Yoichi 砂川陽一