Koshizaka Masaya 越坂理也

… Alternative Names

Masaya Koshizaka 越坂理也

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Researcher Number	30466700
Other IDs
Affiliation (Current)	2025: 千葉大学, 予防医学センター, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 千葉大学, 予防医学センター, 准教授 2020 – 2023: 千葉大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 63030:Chemical substance influence on environment-related / Basic Section 59040:Nutrition science and health science-related Except Principal Investigator Basic Section 52010:General internal medicine-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 化学物質への複合曝露 / 胎児期環境 / 早期血管老化 / 病態解明 / 遅い夕食 / 特定健康診査 / リアルワールド / 慢性腎臓病 / 早期生体マーカー / リスクシミュレーター … More / 予測モデル / 腎機能障害 / 歩行習慣 / HbA1c / BMI / 特定健診 / 予測危険因子 / 早期腎機能障害 … More Except Principal Investigator サルコペニア / R3hdml / 糖尿病性腎症 / 筋腎連関 / 臨床試験 / 老化抑制 / ニコチンアミドアデニンジヌクレオチド / 難治性皮膚潰瘍 / 動脈硬化性疾患 / 悪性腫瘍 / Nicotinamide riboside / NAD前駆体 / 早老症 / 二重盲検無作為化プラセボ対照クロスオーバー試験 / CAVI / 下肢潰瘍 / 動脈硬化 / ニコチンアミドリボシド / NAD / 遺伝的早老症 / ウェルナー症候群 / Werner症候群 / Pericyte / 尿細管細胞 / ポドサイト / 線維芽細胞 / 老化 / 線維化 / 細胞老化 Less

胎児期環境での化学物質への複合曝露が及ぼす早期血管老化への影響の解明Principal Investigator
- Principal Investigator
  
  越坂理也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  Chiba University
R3hdmlが切り開く筋腎連関の機序解明およびCKD・サルコペニアの新規治療戦略
- Principal Investigator
  
  石川崇広
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Chiba University
Innovative treatment and and study of aging suppression mechanism with NAD precursors for aging model disease
- Principal Investigator
  
  Yokote Koutaro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Chiba University
The role of Pericyte Senescence in Diabetic Complications
- Principal Investigator
  
  Maezawa Yoshiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Chiba University
Comprehensive study of risk factors and biomarkers that contribute to elucidation of the pathology of renal disorders due to aging and lifestylePrincipal Investigator
- Principal Investigator
  
  Masaya Koshizaka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Chiba University

All 2023 2022 2021 2020 Other

All Journal Article Presentation Other

[Journal Article] Case of Werner syndrome with significant improvement of refractory skin ulcer despite fibroblast cellular senescence2023
- Author(s)
  Kinoshita Daisuke、Kato Hisaya、Kaneko Hiyori、Ishikawa Takahiro、Teramoto Naoya、Tsukagoshi Ayano、Maeda Yukari、Minamizuka Takuya、Hayashi Aiko、Shoji Mayumi、Sawada Daisuke、Funayama Shinichiro、Koshizaka Masaya、Ogata Hideyuki、Kubota Yoshitaka、Mitsukawa Nobuyuki、Takemoto Minoru、Yokote Koutaro、Maezawa Yoshiro
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 23 Issue: 3 Pages: 239-241
- DOI
  10.1111/ggi.14546
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15682, KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-20K07810
[Journal Article] Quality of life in Werner syndrome and associated subjective foot/ankle symptoms: A cross-sectional survey2022
- Author(s)
  Kitagawa, Y., Amemiya, A., Ogata, H., Koshizaka, M., Shoji, M., Maezawa, Y., Akita, S., Mitsukawa, N., Yokote, K.
- Journal Title
  
  Geriatrics & Gerontology International
  
  Volume: 23(3) Issue: 3 Pages: 188-193
- DOI
  10.1111/ggi.14541
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K19086, KAKENHI-PROJECT-20H03572
[Journal Article] Predictive model and risk engine web application for surgical site infection risk in perioperative patients with type 2 diabetes2022
- Author(s)
  Koshizaka Masaya、Ishibashi Ryoichi、Maeda Yukari、Ishikawa Takahiro、Maezawa Yoshiro、Takemoto Minoru、Yokote Koutaro
- Journal Title
  
  Diabetology International
  
  Volume: 13 Issue: 4 Pages: 657-664
- DOI
  10.1007/s13340-022-00587-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03572
[Journal Article] Lifetime extension and the recent cause of death in Werner syndrome: a retrospective study from 2011 to 20202022
- Author(s)
  Kato Hisaya、Koshizaka Masaya、Kaneko Hiyori、Maezawa Yoshiro、Yokote Koutaro
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 17 Issue: 1 Pages: 226-226
- DOI
  10.1186/s13023-022-02383-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15682, KAKENHI-PROJECT-20H03572
[Journal Article] Homozygous familial lipoprotein lipase deficiency without obvious coronary artery stenosis2022
- Author(s)
  Minamizuka Takuya、Kobayashi Junji、Tada Hayato、Koshizaka Masaya、Maezawa Yoshiro、Yokote Koutaro
- Journal Title
  
  Clinical Biochemistry
  
  Volume: 108 Pages: 42-45
- DOI
  10.1016/j.clinbiochem.2022.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03572
[Journal Article] Correction of Hypercortisolemia with an Improved Cognitive Function and Muscle Mass after Transsphenoidal Surgery in an Older Patient with Cushing's Disease2022
- Author(s)
  Terayama Ryo、Ishikawa Takahiro、Ishiwata Kazuki、Sato Ai、Minamizuka Takuya、Ohno Tomohiro、Kono Satomi、Yamamoto Masashi、Yokoh Hidetaka、Nagano Hidekazu、Koshizaka Masaya、Suzuki Sawako、Koide Hisashi、Maezawa Yoshiro、Yokote Koutaro
- Journal Title
  
  Intern. Med.
  
  Volume: 61 Issue: 22 Pages: 3391-3399
- DOI
  10.2169/internalmedicine.8326-21
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2022-11-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08325, KAKENHI-PROJECT-22H04922, KAKENHI-PROJECT-20H03572
[Journal Article] Rothmund‐Thomson syndrome investigated by two nationwide surveys in Japan2022
- Author(s)
  Kaneko Hideo、Takemoto Minoru、Murakami Hiroaki、Ihara Kenji、Kosaki Rika、Motegi Sei‐ichiro、Taniguchi Akira、Matsuo Muneaki、Yamazaki Naoya、Nishigori Chikako、Takita Junko、Koshizaka Masaya、Maezawa Yoshiro、Yokote Koutaro
- Journal Title
  
  Pediatrics International
  
  Volume: 64 Issue: 1
- DOI
  10.1111/ped.15120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-20K07810
[Journal Article] Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome2021
- Author(s)
  Kato H, Maezawa Y, Takayama N, Ouchi Y, Kaneko H, Kinoshita D, Takada-Watanabe A, Oshima M, Koshizaka M, Ogata H, Kubota Y, Mitsukawa N, Eto K, Iwama A, Yokote K.
- Journal Title
  
  Aging (Albany NY)
  
  Volume: 13 Issue: 4 Pages: 4946-4961
- DOI
  10.18632/aging.202696
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07651, KAKENHI-PROJECT-20H00524, KAKENHI-PROJECT-20H03572, KAKENHI-PROJECT-19K23939, KAKENHI-PROJECT-17KK0189, KAKENHI-PROJECT-20K16542, KAKENHI-PROJECT-18H04164
[Journal Article] Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan2020
- Author(s)
  Koshizaka M, Maezawa Y, Maeda Y, Shoji M, Kato H, Kaneko H, Ishikawa T, Kinoshita D, Kobayashi K, Kawashima J, Sekiguchi A, Motegi SI, Nakagami H, Yamada Y, Tsukamoto S, Taniguchi A, Sugimoto K, Shoda Y, Hashimoto K, Yoshimura T, Suzuki D, Kuzuya M, Takemoto M, Yokote K.
- Journal Title
  
  Aging
  
  Volume: 12 Issue: 24 Pages: 24940-24956
- DOI
  10.18632/aging.202441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K11599, KAKENHI-PROJECT-20H00524, KAKENHI-PROJECT-20H03572
[Journal Article] Effects of ipragliflozin versus metformin in combination with sitagliptin on bone and muscle in Japanese patients with type?2 diabetes mellitus: Subanalysis of a prospective, randomized, controlled study (PRIME‐V study)2020
- Author(s)
  Koshizaka M, Ishikawa K, Ishibashi R, Maezawa Y, Sakamoto K, Uchida D et al.
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 2 Pages: 200-206
- DOI
  10.1111/jdi.13340
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K11599, KAKENHI-PROJECT-20H00524
[Journal Article] Comparison of Visceral Fat Reduction by Ipragliflozin and Metformin in Elderly Type 2 Diabetes Patients: Sub-Analysis of a Randomized-Controlled Study2020
- Author(s)
  Koshizaka Masaya、Ishikawa Ko、Ishibashi Ryoichi、Takahashi Sho、Sakamoto Kenichi、Yokoh Hidetaka、Baba Yusuke、Ide Shintaro、Ide Kana、Ishikawa Takahiro、Onishi Shunichiro、Kobayashi Kazuki、Takemoto Minoru、Horikoshi Takuro、Shimofusa Ryota、Maezawa Yoshiro、Yokote Koutaro
- Journal Title
  
  Diabetes Therapy
  
  Volume: 12 Issue: 1 Pages: 183-196
- DOI
  10.1007/s13300-020-00949-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07810, KAKENHI-PROJECT-20K11599, KAKENHI-PROJECT-20H00524, KAKENHI-PROJECT-20H03572
[Presentation] Role of Cellular Senescence and Epigenetic Drift in Interstitial Fibrosis of Diabetic Kidney Disease.2022
- Author(s)
  Ayano Tsukagoshi, Yoshiro Maezawa, Shintaro Ide, Hiyori Kaneko, Kana Ide, Masaya Koshizaka, Koutaro Yokote.
- Organizer
  American Society of Nephrology kidney week 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03572
[Presentation] 早老症ウェルナー症候群に関する臨床研究の歩み，そして希望-　ウェルナー症候群レジストリからEMPOWER試験まで-2021
- Author(s)
  越坂理也
- Organizer
  第63回日本老年医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K19437
[Presentation] 新しい肥満治療の可能性を探る　肥満治療における薬物療法の現状と展望2021
- Author(s)
  越坂理也
- Organizer
  第41回日本肥満学会・第38回日本肥満症治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K11599
[Presentation] Glucagon-like peptide-1 receptor agonists decrease cancer incidences in type 2 diabetes: a cohort study using the National Database of Health Insurance Claims of Japan2020
- Author(s)
  Ryoichi Ishibashi, Masaya Koshizaka, Tomoki Ishikawa, Naohiro Mitsutake, Jumpei Sato, Kazuo Goda, Masaru Kitsuregawa, Koutaro Yokote
- Organizer
  56th Annual Meeting of the European Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11599
[Presentation] Glucagon-like peptide-1 receptor agonists reduce cerebral and cardiovascular events: real world analysis using the National Database of Japan2020
- Author(s)
  Masaya Koshizaka, Ryoichi Ishibashi, Tomoki Ishikawa, Kazuo Goda, Jumpei Sato, Masaru Kitsuregawa, Koutaro Yokote, Naohiro Mitsutake
- Organizer
  56th Annual Meeting of the European Association for the Study of Diabetes
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11599
[Presentation] メディカルスタッフカンファレンス「労作時の息切れを主訴に来院した38歳男性」2020
- Author(s)
  越坂理也, 丸山篤芳, 安楽香奈子, 五十嵐大輔
- Organizer
  第52回日本動脈硬化学会総会・学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K11599
[Presentation] シンポジウム９　DNA損傷応答と老化の表現型「早老症に見る細胞老化と個体老化」2020
- Author(s)
  前澤善朗、加藤尚也、越坂理也、横手幸太郎
- Organizer
  第20回抗加齢医学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03572
[Presentation] Predictive Risk Factors for Renal Dysfunction and Cardiovascular Disease: An Analysis Using Medical Checkup Data2020
- Author(s)
  Ryo Terayama, Masaya Koshizaka, Takahisa Shibata, Toshiaki Ban, Yoshiro Maezawa, Koutaro Yokote
- Organizer
  American Diabetes Association (ADA) 80th Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K11599
[Presentation] 特定健康診査データを用いたリアルワールドにおける心血管イベント・腎機能低下リスク因子の検討2020
- Author(s)
  寺山諒, 越坂理也, 柴田貴久, 伴俊明, 前澤善朗, 横手幸太郎
- Organizer
  第63回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-20K11599
[Presentation] Role of Transcription Factor TCF21 in Adipocyte Progenitor Cells of Visceral Fat2020
- Author(s)
  Takuya Minamizuka, Yoshiro Maezawa, Haruhide Udagawa, Yusuke Baba, Masaya Koshizaka, Yusuke Endo, Kazuki Yasuda, Koutaro Yokote
- Organizer
  American Diabetes Association's 80th Scientific Sessions
- Data Source
  KAKENHI-PROJECT-20H03572
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1. Maezawa Yoshiro (80436443)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
2. 竹本稔 (60447307)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
3. Yokote Koutaro (20312944)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 加藤尚也 (90841974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 石川崇広 (00749426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小倉正恒 (30532486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 江口哲史 (70595826)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 櫻井健一 (80323434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 森千里 (90174375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. OUCHI Yasuo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 雨宮歩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koshizaka Masaya 越坂 理也

Masaya Koshizaka 越坂 理也

Research Projects

Research Products

Co-Researchers

胎児期環境での化学物質への複合曝露が及ぼす早期血管老化への影響の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

R3hdmlが切り開く筋腎連関の機序解明およびCKD・サルコペニアの新規治療戦略

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innovative treatment and and study of aging suppression mechanism with NAD precursors for aging model disease

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of Pericyte Senescence in Diabetic Complications

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive study of risk factors and biomarkers that contribute to elucidation of the pathology of renal disorders due to aging and lifestylePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Case of Werner syndrome with significant improvement of refractory skin ulcer despite fibroblast cellular senescence2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quality of life in Werner syndrome and associated subjective foot/ankle symptoms: A cross-sectional survey2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Predictive model and risk engine web application for surgical site infection risk in perioperative patients with type 2 diabetes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lifetime extension and the recent cause of death in Werner syndrome: a retrospective study from 2011 to 20202022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Homozygous familial lipoprotein lipase deficiency without obvious coronary artery stenosis2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Correction of Hypercortisolemia with an Improved Cognitive Function and Muscle Mass after Transsphenoidal Surgery in an Older Patient with Cushing&apos;s Disease2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Rothmund‐Thomson syndrome investigated by two nationwide surveys in Japan2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fibroblasts from different body parts exhibit distinct phenotypes in adult progeria Werner syndrome2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Time gap between the onset and diagnosis in Werner syndrome: a nationwide survey and the 2020 registry in Japan2020

Author(s)

Koshizaka Masaya 越坂理也

Masaya Koshizaka 越坂理也

[Journal Article] Correction of Hypercortisolemia with an Improved Cognitive Function and Muscle Mass after Transsphenoidal Surgery in an Older Patient with Cushing's Disease2022

[Presentation] 早老症ウェルナー症候群に関する臨床研究の歩み，そして希望-　ウェルナー症候群レジストリからEMPOWER試験まで-2021

[Presentation] 新しい肥満治療の可能性を探る　肥満治療における薬物療法の現状と展望2021

[Presentation] シンポジウム９　DNA損傷応答と老化の表現型「早老症に見る細胞老化と個体老化」2020