Horie Masanori 堀江祐範

Researcher Number	30514591
Other IDs
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長
Affiliation (based on the past Project Information) *help	2020 – 2024: 国立研究開発法人産業技術総合研究所, 生命工学領域, 研究グループ長 2021 – 2022: 国立研究開発法人産業技術総合研究所, 生命工学領域, 上級主任研究員 2017 – 2019: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2017: 国立研究開発法人産業技術総合研究所, 健康工学研究部門, 研究員 2016: 国立研究開発法人産業技術総合研究所, その他部局等, 研究員 … More 2015 – 2016: 国立研究開発法人産業技術総合研究所, 健康工学研究部門, 主任研究員 2015: 国立研究開発法人産業技術総合研究所, 健康工学研究門, 研究員 2014: 独立行政法人産業技術総合研究所, 健康工学研究部門, 主任研究員 2011 – 2013: 産業医科大学, 産業生態科学研究所, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 63030:Chemical substance influence on environment-related / Nanomaterials chemistry Except Principal Investigator Basic Section 64020:Environmental load reduction and remediation-related / Basic Section 08030:Family and consumer sciences, and culture and living-related / Applied health science / Eating habits / Biomolecular chemistry / Respiratory organ internal medicine
Keywords	Principal Investigator 粒子計測 / ケモカイン / オートファジー / 貪食 / 炎症応答 / 細胞影響 / マクロファージ / ポリ乳酸 / ポリウレタン / サイトカイン … More / 細胞毒性 / 培養細胞 / マイクロプラスチック / ナノオブジェクト / 吸入 / 酸化ストレス / ナノ粒子 / IgE / アレルギー / カーボンナノチューブ … More Except Principal Investigator 浄水 / 光触媒 / 水浄化 / 光触媒酸化チタン / ナノニードル / アラゴナイト / メカノ殺菌 / 結晶成長 / ナノ構造作製 / 遺伝毒性・生態毒性 / 環境配慮設計 / 水資源・水システム / 更年期症状 / エストロゲン受容体 / フィトエストロゲン / エストロゲン / カシス / 眼疾患 / 合併症 / 生活習慣病 / 細胞試験 / 動物試験 / 酸化ストレス / 発症メカニズム解析 / 機能性因子 / バイオマーカー / 早期診断 / 糖尿病 / 一重項酸素 / 酸化ストレスマーカー / ヒト試験 / 細胞モデル / 動物モデル / 非アルコール性肝障害 / 機能性成分 / 食品科学 / パン / 2'-ヒドロキシゲニステイン / アグリコン / 調理加工 / イソフラボン / アピオス / ストレスマーカー / 炎症マーカー / surface activity / amphibian skin / antimicrobial peptide / nanodisc / NMR / 泡 / 立体構造解析 / 抗菌 / 両生類 / ナノディスク / 溶血 / ミセル / 表面張力 / ペプチド / 好中球 / 肺 / CINC / 気管内注入 / レゴリス Less

Synthesis of Photocatalytic Materials with Mechano-Bactericidal Effects and Elucidation of Their Bacteria Treatment Mechanisms in Water
- Principal Investigator
  
  根岸信彰
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 64020:Environmental load reduction and remediation-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Search for novel plant-derived estrogens and evaluation of their effect on alleviation menopausal symptoms
- Principal Investigator
  
  Nanashima Naoki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Aomori University of Health and Welfare
  Hirosaki University
Examination of cellular effects caused by microplastics and their mechanismsPrincipal Investigator
- Principal Investigator
  
  Horie Masanori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63030:Chemical substance influence on environment-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
非アルコール性肝障害の発症機序解明および早期診断法の確立と予防法の提案
- Principal Investigator
  
  吉田康一
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Applied health science
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Utilization and potential of functionality in Apios.
- Principal Investigator
  
  Nara Kazuhiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Eating habits
- Research Institution
  Jissen Women's University
Possibility of skin care material using Pxt peptides from amphibian (Xenopus tropicalis) skin
- Principal Investigator
  
  Shigeri Yasushi
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomolecular chemistry
- Research Institution
  Wakayama Medical University
  National Institute of Advanced Industrial Science and Technology
Evaluation of allergy aggravation effect caused by inhalation of carbonb nanotubePrincipal Investigator
- Principal Investigator
  
  Horie Masanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Nanomaterials chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
  University of Occupational and Environmental Health, Japan
Development of estimamation system of harmful effect under the space environment
- Principal Investigator
  
  MORIMOTO Yasuo
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  University of Occupational and Environmental Health, Japan

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 2011 Other

All Journal Article Presentation Other

[Journal Article] Microorganisms involved in the preparation of “<i>Sushiko</i>,” a fermented food produced in Tsugaru, Aomori, Japan2023
- Author(s)
  堀江祐範，七島直樹
- Journal Title
  
  Journal of the Japanese Society of Taste Technology
  
  Volume: 22 Issue: 1 Pages: 6-13
- DOI
  10.11274/bimi.22.1_6
- ISSN
  2186-7224, 2186-7232
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K02038, KAKENHI-PROJECT-20K02402
[Journal Article] Exosomal MicroRNA as Biomarkers for Diagnosing or Monitoring the Progression of Ovarian Clear Cell Carcinoma: A Pilot Study2022
- Author(s)
  Horie Kayo、Nanashima Naoki、Yokoyama Yoshihito、Yoshioka Haruhiko、Watanabe Jun
- Journal Title
  
  Molecules
  
  Volume: 27 Issue: 12 Pages: 3953-3953
- DOI
  10.3390/molecules27123953
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07748, KAKENHI-PROJECT-20K02402, KAKENHI-PROJECT-20K09589
[Journal Article] Hypocholesterolemic Effect of Blackcurrant ( Ribes nigrum) Extract in Healthy Female Subjects: A Pilot Study2021
- Author(s)
  Naoki Nanashima, Kayo Horie, Maiko Kitajima, Shizuka Takamagi, Kasumi Mikami, Naoya In, Toshiko Tomisawa
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 13 Pages: 4085-4085
- DOI
  10.3390/molecules26134085
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K02402
[Journal Article] Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.2021
- Author(s)
  Horie K, Nanashima N, Maeda H, Tomisawa T, Oey I.
- Journal Title
  
  Nutrients
  
  Volume: 13 Issue: 2 Pages: 560-560
- DOI
  10.3390/nu13020560
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K02402
[Journal Article] Potential Vasculoprotective Effects of Blackcurrant ( Ribes nigrum) Extract in Diabetic KK-A y Mice2021
- Author(s)
  Kayo Horie, Hayato Maeda, Naoki Nanashima, Indrawati Oey
- Journal Title
  
  Molecules
  
  Volume: 26 Issue: 21 Pages: 6459-6459
- DOI
  10.3390/molecules26216459
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K02402
[Journal Article] Blackcurrant (Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats2020
- Author(s)
  Naoki Nanashima, Kayo Horie, Kanako Yamanouchi, Toshiko Tomisawa, Maiko Kitajima, Indrawati Oey, Hayato Maeda
- Journal Title
  
  Nutrients
  
  Volume: 12 Issue: 5 Pages: 1541-1541
- DOI
  10.3390/nu12051541
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K02402
[Journal Article] Comprehensive measurements of hydroxylinoleate and hydroxyarachidonate isomers in blood samples from primary open-angle glaucoma patients and controls2019
- Author(s)
  Umeno Aya、Tanito Masaki、Kaidzu Sachiko、Takai Yasuyuki、Horie Masanori、Yoshida Yasukazu
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 2171-2171
- DOI
  10.1038/s41598-018-36952-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K17951, KAKENHI-PROJECT-17H00881
[Journal Article] Early diagnosis of type 2 diabetes based on multiple biomarkers and non-invasive indices2018
- Author(s)
  Aya Umeno, Toshiki Fukui, Yoshiko Hashimoto, Masatoshi Kataoka, Yoshihisa Hagihara, Hidenori Nagai, Masanori Horie, Mototada Shichiri, Kohzoh Yoshino, Yasukazu Yoshida
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 62 Issue: 2 Pages: 187-194
- DOI
  10.3164/jcbn.17-81
- NAID
  130006407483
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K16538, KAKENHI-PROJECT-17H00881
[Journal Article] Effects of Different Bread-making Methods on the Isoflavone Composition of Groundnut Bread2017
- Author(s)
  奈良一寛、堀江祐範、髙城彩湖、山﨑薫
- Journal Title
  
  Nippon Shokuhin Kagaku Kogaku Kaishi
  
  Volume: 64 Issue: 11 Pages: 542-548
- DOI
  10.3136/nskkk.64.542
- NAID
  130006224082
- ISSN
  1341-027X, 1881-6681
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00825
[Journal Article] Metal ion release of manufactured metal ox-ide nanoparticles is involved in the allergic response to inhaled ovalbumin in mice2016
- Author(s)
  Horie M, Stowe M, Tabei M, Kuroda E.
- Journal Title
  
  Occupational Diseases and Environmental Medicine
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25871005
[Journal Article] Pharyngeal aspiration of single-wall carbon nanotubes aggravates allergic reaction to inhaled ovalbumin in mice2016
- Author(s)
  Horie M, Endoh S, Maru J, Kato H, Fujita K.
- Journal Title
  
  Toxicological & Environmental Chemistry
  
  Volume: 印刷中 Issue: 1 Pages: 134-147
- DOI
  10.1080/02772248.2016.1147042
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25871005
[Journal Article] Physicochemical and biological characterizations of Pxt peptides from amphibian (Xenopus tropicalis) skin2016
- Author(s)
  Yasushi Shigeri, Masanori Horie, Tsuyoshi Yoshida, Yoshihisa Hagihara, Tomohiro Imura, Hidetoshi Inagaki, Yoshikazu Haramoto, Yuzuru Ito, and Makoto Asashima
- Journal Title
  
  Journal of Biochemistry
  
  Volume: -
- NAID
  40020869436
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01814
[Journal Article] Pharyngeal aspiration of metal oxide nanoparticles showed potential of allergy aggravation effect to inhaled ovalbumin.2015
- Author(s)
  Horie M, Stowe M, Tabei M, Kuroda E.
- Journal Title
  
  Inhalation Toxicology
  
  Volume: 27 Issue: 3 Pages: 181-190
- DOI
  10.3109/08958378.2015.1026618
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25871005
[Journal Article] 月面ダストの生体影響2011
- Author(s)
  神原辰徳、堀江祐範、森本泰夫、青木滋、三木猛生
- Journal Title
  
  空気清浄
  
  Volume: 49(4) Pages: 54-59
- NAID
  10030261173
- Data Source
  KAKENHI-PROJECT-23591172
[Presentation] カシスに含まれる新規フィトエストロゲンの探索および活性評価2023
- Author(s)
  七島直樹、堀江香代、前多隼人、加藤陽治
- Organizer
  2023年度青森県保健医療福祉研究発表会日本ヒューマンケア科学学会第16回学術集会合同集会
- Data Source
  KAKENHI-PROJECT-20K02402
[Presentation] ヒト皮膚線維芽細胞におけるEstrogen-related receptorαの機能解析2023
- Author(s)
  七島直樹、乗鞍敏夫、中野学、堀江香代
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20K02402
[Presentation] カシス抽出物は骨芽細胞様細胞の分化を誘導する2023
- Author(s)
  七島直樹、堀江香代、Indrawati Oey
- Organizer
  第77回日本栄養・食料学会
- Data Source
  KAKENHI-PROJECT-20K02402
[Presentation] カシス抽出物は更年期モデルラットにおける脂質異常症を軽減する2022
- Author(s)
  七島直樹、堀江香代、前多隼人、Indrawati Oey
- Organizer
  2022年度青森県保健医療福祉研究発表会・日本ヒューマンケア科学学会第15回学術集会合同集会
- Data Source
  KAKENHI-PROJECT-20K02402
[Presentation] Alleviating effects of blackcurrant extract against dyslipidemia in menopausal and diabetic animal models2022
- Author(s)
  七島直樹、堀江香代、前多隼人
- Organizer
  第45回日本分子生物学会年会日本生物物理学会共催
- Data Source
  KAKENHI-PROJECT-20K02402
[Presentation] 更年期モデルラットにおけるカシス抽出物の脂質異常症に対する軽減効果2020
- Author(s)
  Naoki Nanashima, Kayo Horie, Indrawati Oey, Hayato Maeda
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20K02402
[Presentation] 製パン法の違いによるアピオスイソフラボンの差異2016
- Author(s)
  奈良一寛・堀江祐範・山﨑薫・石神優紀子・髙城彩湖・小俣沙織
- Organizer
  日本調理科学会
- Place of Presentation
  名古屋学芸大学
- Year and Date
  2016-08-28
- Data Source
  KAKENHI-PROJECT-16K00825
[Presentation] 気管内注入による月レゴリスの有害性評価2013
- Author(s)
  神原辰徳、堀江祐範、李秉雨、大藪貴子、明星敏彦、本間善之、森本泰夫
- Organizer
  第85回　日本産業衛生学会
- Place of Presentation
  名古屋国際会議場（松山）
- Data Source
  KAKENHI-PROJECT-23591172
[Presentation] 気管内注入による月レゴリスの有害性評価2013
- Author(s)
  神原辰徳、堀江祐範、李秉雨、大藪貴子、明星敏彦、本間善之、森本泰夫
- Organizer
  第85回日本産業衛生学会
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-23591172
[Presentation] 月粉じんの気管内注入による有害性評価2011
- Author(s)
  神原辰徳、堀江祐範、森本泰夫、青木滋、三木猛生
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢エクセルホテル東急（金沢）
- Data Source
  KAKENHI-PROJECT-23591172
[Presentation] 月粉じんの気管内注入による有害性評価2011
- Author(s)
  神原辰徳、堀江祐範、森本泰夫、三木猛生、本間善之、青木滋
- Organizer
  第57回日本宇宙航空環境医学会大会
- Place of Presentation
  つくば
- Data Source
  KAKENHI-PROJECT-23591172
[Presentation] 月粉じんの気管内注入による有害性評価2011
- Author(s)
  神原辰徳、堀江祐範、森本泰夫、青木滋、三木猛生
- Organizer
  フォーラム2011衛生薬学・環境トキシコロジー
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-23591172
[]

1. KURODA Etsushi (10299604)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. MORIMOTO Yasuo (30258628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. IZUMI Hiroto (50289576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Shigeri Yasushi (90357187)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. Nara Kazuhiro (60540903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. Nanashima Naoki (80333730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
7. 神原辰徳 (50596450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. 井村知弘 (10371022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. 吉田康一 (90358333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 常山幸一 (10293341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 七里元督 (20434780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 谷戸正樹 (30284037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中村強 (30581912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 室冨和俊 (40635281)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 太田雅規 (70341526)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 堀江香代 (30626825)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
17. 前多隼人 (80507731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
18. 加藤晴久 (10462839)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 小川道永 (80361624)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 田部井陽介 (40555083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 根岸信彰 (90270694)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 王正明 (10356610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 楊英男 (50561007)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 黒崎直子 (60337706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 根本直樹 (60633386)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 灘浩樹 (90357682)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 梅野彩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 渡辺純

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Horie Masanori 堀江 祐範

Research Projects

Research Products

Co-Researchers

Synthesis of Photocatalytic Materials with Mechano-Bactericidal Effects and Elucidation of Their Bacteria Treatment Mechanisms in Water

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for novel plant-derived estrogens and evaluation of their effect on alleviation menopausal symptoms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of cellular effects caused by microplastics and their mechanismsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

非アルコール性肝障害の発症機序解明および早期診断法の確立と予防法の提案

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Utilization and potential of functionality in Apios.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Possibility of skin care material using Pxt peptides from amphibian (Xenopus tropicalis) skin

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of allergy aggravation effect caused by inhalation of carbonb nanotubePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of estimamation system of harmful effect under the space environment

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Microorganisms involved in the preparation of “<i>Sushiko</i>,” a fermented food produced in Tsugaru, Aomori, Japan2023

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Exosomal MicroRNA as Biomarkers for Diagnosing or Monitoring the Progression of Ovarian Clear Cell Carcinoma: A Pilot Study2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hypocholesterolemic Effect of Blackcurrant ( Ribes nigrum) Extract in Healthy Female Subjects: A Pilot Study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Potential Vasculoprotective Effects of Blackcurrant ( Ribes nigrum) Extract in Diabetic KK-A y Mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Blackcurrant (Ribes nigrum) Extract Prevents Dyslipidemia and Hepatic Steatosis in Ovariectomized Rats2020

Horie Masanori 堀江祐範