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Hirohashi Yoshihiko  廣橋 良彦

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HIROHASHI Yoshihiko  廣橋 良彦

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Researcher Number 30516901
External Links
Affiliation (Current) 2025: 札幌医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2016 – 2024: 札幌医科大学, 医学部, 准教授
2014 – 2015: 札幌医科大学, 医学部, 講師
2009 – 2014: 札幌医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Experimental pathology / Human pathology
Except Principal Investigator
Human pathology / Basic Section 55010:General surgery and pediatric surgery-related / Basic Section 55020:Digestive surgery-related / Basic Section 27040:Biofunction and bioprocess engineering-related / Basic Section 56030:Urology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 49020:Human pathology-related / Urology / General surgery
Keywords
Principal Investigator
腫瘍抗原 / T細胞受容体 / 腫瘍浸潤リンパ球 / 1細胞解析 / 腫瘍微小環境 / OR7C1 / がん精巣抗原 / 免疫療法 / がん幹細胞 / 1細胞遺伝子発現解析 … More / 空間遺伝子発現解析 / バイオマーカー / TCR / 悪性黒色腫 / 単細胞解析 / 細胞傷害性T細胞 / CTL / BORIS / 細胞障害性T細胞 / 班精巣抗原 / 抗原分子 / 大腸がん / DNAJB8 / がん抗原 … More
Except Principal Investigator
がん抗原 / がん幹細胞 / 乳癌 / 腫瘍免疫 / 免疫 / 幹細胞 / がん免疫療法 / Cancer stem cell / CTL / 分子病理 / 抗腫瘍免疫 / 癌細胞の浸潤・増殖 / 細胞外マトリックス / がん関連線維芽細胞 / 薬剤耐性 / GPR77 / Versican / I型コラーゲン / CAF / 線維性癌間質反応 / がん抑制性CAF / がん促進性CAF / がん関連線維芽細胞(CAF) / 線維性 / 大腸癌 / 内因性リガンド / 大腸がん幹細胞 / RTP1 / 細胞膜輸送 / 嗅覚受容体 / 膀胱がん / 抗体薬物複合体 / 抗体医薬 / イムノヒストグラム / 抗腫瘍免疫応答 / 術前治療 / 直腸癌 / がん免疫 / 細胞接着 / CD155 / がん悪性化 / マルチオミクス解析 / 癌悪性化 / 発現欠損株 / 扁平上皮癌 / 頭頸部がん / PVR / cytotoxic T-cell / リンパ球 / 免疫関与う / cytotoxic T cell / 免疫寛容 / cytotoxic T lymphocyte / リンパ節転移 / breast cancer / anti-PD-L1抗体 / ERO1-Lα / 免疫複合療法 / トリプルネガティブ乳癌 / 細胞・組織 / 分子生物学 / 免疫学 / 腫瘍学 / 病理学 / Tumor antigen / 免疫病理診断 / Immunohistochemistry / Immune response / Tumor immune escape / Single cell analysis / Tumor microenvironment / 免疫病理バイオマーカー / 単細胞遺伝子発現解析 / がん免疫応答 / がん組織微小環境 / 腫瘍組織微小環境 / 免疫チェックポイント阻害剤 / シングルセル遺伝子解析 / 単細胞遺伝子解析 / がん最適化治療 / バイオマーカー / 免疫組織染色 / T細胞抗原受容体 / 腫瘍微小環境 / フローサイトメトリー / 免疫療法 / 骨髄由来抑制細胞 / 化学療法 / 尿路上皮癌 / side population / 膵 / 癌 / T細胞 / 抗原 / がん / CTLエピトープ / 細胞障害性T細胞 / ペプチド / Survivin / OR7C1 / DNAJB8 / CEP55 / がんワクチン / CIC / CSC / CSC/CIC / SP法 / 分子標的 / 癌免疫 / 腫瘍抗原 / 癌幹細胞 Less
  • Research Projects

    (16 results)
  • Research Products

    (183 results)
  • Co-Researchers

    (49 People)
  •  A novel immunotherapy targeting cisplatin resistance-associated molecular pathways in bladder cancer

    • Principal Investigator
      水江 由佳
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Sapporo Medical University
  •  Elucidation of the selective expression mechanism and significance of olfactory receptors in cancer stem cells.

    • Principal Investigator
      福谷 洋介
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 27040:Biofunction and bioprocess engineering-related
    • Research Institution
      Tokyo University of Agriculture and Technology
  •  Next-generation tumor microenvironment analysis through integration of pathological and immunological analysesPrincipal Investigator

    • Principal Investigator
      廣橋 良彦
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Sapporo Medical University
  •  高悪性度大腸癌に対するがん促進性CAFを標的とした新規治療法開発の基盤研究

    • Principal Investigator
      上野 秀樹
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      National Defense Medical College
  •  イムノヒストグラムを用いた直腸癌に対する術前化学療法の新規治療効果予測法の開発

    • Principal Investigator
      奥谷 浩一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Sapporo Medical University
  •  Integrated understanding of cell adhesion and cancer immune evasion of PVR

    • Principal Investigator
      Murata Masaki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Sapporo Medical University
  •  development of combined immunotherapy targeting ero1 in triple negative breast cancer

    • Principal Investigator
      Kutomi Goro
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Sapporo Medical University
  •  乳癌の転移巣を伴うリンパ節内のT-cellにおける免疫応答

    • Principal Investigator
      島 宏彰
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Sapporo Medical University
  •  Single cell analysis of tumor-microenvironment based on TIL functionsPrincipal Investigator

    • Principal Investigator
      HIROHASHI Yoshihiko
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Sapporo Medical University
  •  Basic research on the immunohistological categorization of tumor microenvironment

    • Principal Investigator
      TORIGOE Toshihiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Establishment of novel chemoimmunotherapy for urothelial cancer

    • Principal Investigator
      Kitamura Hiroshi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      University of Toyama
  •  Immunological aspects of cancer stem cell and spermatogenesisPrincipal Investigator

    • Principal Investigator
      HIROHASHI Yoshihiko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Experimental pathology
    • Research Institution
      Sapporo Medical University
  •  Immunological analysis of treatment resistant cancer stem cellsPrincipal Investigator

    • Principal Investigator
      HIROHASHI Yoshihiko
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Developing a novel vaccine therapy targeting cancer stem cells

    • Principal Investigator
      HIRATA Koichi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      Sapporo Medical University
  •  Molecular immunopathology of human cancer stem cell

    • Principal Investigator
      SATO Noriyuki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University
  •  Basic studies for the immune responses against cancer stem cells of sold tumors

    • Principal Investigator
      TORIGOE Toshihiko
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Human pathology
    • Research Institution
      Sapporo Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Book Patent

  • [Book] Cancer, Immunology and Photonics Science. Optical Devices and Systems, Biomedical and Green Technologies2010

    • Author(s)
      Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Shingo Ichimiya, Yasuaki Tamura and Toshihiko Torigoe
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Book] Cancer, Immunology and Photonics S cience. Optical Devices and Systems, Biomedical and Green Technologies.2010

    • Author(s)
      Noriyuki Sato, Yoshihiko Hirohashi, Tomohide Tsukahara, Shingo Ichimiya, Yasuaki Tamura and Toshihiko Torigoe
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Book] がん免疫療法の標的抗原、がん免疫療法-実用化へのチャレンジ-2010

    • Author(s)
      守田玲菜、廣橋良彦、鳥越俊彦、佐藤昇志
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Book] バイオ医薬の開発技術とシーズ.第30章がんペプチド免疫治療2009

    • Author(s)
      佐藤昇志、廣橋良彦、塚原智英、田村保明、一宮慎吾、鳥越俊彦
    • Publisher
      シーエムシー出版
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] CD8-positive T Cell Infiltration With Human Leukocyte Antigen Class 1 Expression Predicts Patients With Stage IV Colorectal Cancer Survival.2024

    • Author(s)
      Satoyoshi T, Hirohashi Y, Okuya K, Miyo M, Akizuki E, Ishii M, Miura R, Kubo T, Murata K, Kanaseki T, Tsukahara T, Takemasa I, Torigoe T
    • Journal Title

      Anticancer Res

      Volume: 44 Issue: 4 Pages: 1603-1610

    • DOI

      10.21873/anticanres.16958

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27387
  • [Journal Article] Aldehyde Dehydrogenese-1 High Cancer Stem-like Cells/Cancer-initiating Cells Escape from Cytotoxic T Lymphocytes due to Lower Expression of Human Leukocyte Antigen Class 12024

    • Author(s)
      Tomohide Shirosaki, Noriko Kawai, Yuma Ebihara, Aiko Murai, Terufumi Kubo, Rena Morita, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Toshiaki Shichinohe, Yoshihiko Hirohashi, Satoshi Hirano, Toshihiko Torigoe
    • Journal Title

      Anticancer Res

      Volume: 44 Issue: 5 Pages: 1877-1883

    • DOI

      10.21873/anticanres.16989

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27387
  • [Journal Article] Assessment of cancer cell-expressed HLA class I molecules and their immunopathological implications2024

    • Author(s)
      Terufumi Kubo, Shiori Asano, Kenta Sasaki, Kenji Murata, Takayuki Kanaseki, Tomohide Tsukahara, Yoshihiko Hirohashi, Toshihiko Torigoe
    • Journal Title

      HLA

      Volume: 103 Issue: 5

    • DOI

      10.1111/tan.15472

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K27387
  • [Journal Article] Prognostic significance of immunohistochemical classification utilizing biopsy specimens in patients with extensive-disease small-cell lung cancer treated with first-line chemotherapy and immune checkpoint inhibitors2024

    • Author(s)
      Shijubou N, Sumi T, Kubo T, Sasaki K, Tsukahara T, Kanaseki T, Murata K, Keira Y, Terai K, Ikeda T, Yamada Y, Chiba H, Hirohashi Y, Torigoe T
    • Journal Title

      J Cancer Res Clin Oncol

      Volume: 150 Issue: 3 Pages: 125-125

    • DOI

      10.1007/s00432-024-05652-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27387
  • [Journal Article] Cisplatin resistance driver claspin is a target for immunotherapy in urothelial carcinoma2023

    • Author(s)
      Yamada S, Miyata H, Isono M, Hori K, Yanagawa J, Murai A, Minowa T, Mizue Y, Sasaki K, Murata K, Tokita S, Nakatsugawa M, Iwabuchi S, Hashimoto S, Kubo T, Kanaseki T, Tsukahara T, Abe T, Shinohara N, Hirohashi Y, Torigoe T.
    • Journal Title

      Cancer Immunology Immunotherapy

      Volume: Online ahead of print. Issue: 7 Pages: 2057-2065

    • DOI

      10.1007/s00262-023-03388-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-23K14555
  • [Journal Article] Fusion with type 2 macrophages induces melanoma cell heterogeneity that potentiates immunological escape from cytotoxic T lymphocytes2023

    • Author(s)
      Minowa T, Hirohashi Y, Murata K, Sasaki K, Handa T, Nakatsugawa M, Mizue Y, Murai A, Kubo T, Kanaseki T, Tsukahara T, Iwabuchi S, Hashimoto S, Ishida-Yamamoto A, Uhara H, Torigoe T.
    • Journal Title

      J Pathol

      Volume: Online ahead of print. Issue: 3 Pages: 304-316

    • DOI

      10.1002/path.6083

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03460
  • [Journal Article] Eribulin is an immune potentiator in breast cancer that upregulates human leukocyte antigen class I expression via the induction of NOD-like receptor family CARD domain-containing 52023

    • Author(s)
      Wada A, Hirohashi Y, Kutomi G, Murata K, Iwabuchi S, Mizue Y, Murai A, Kyuno D, Shima H, Minowa T, Sasaki K, Kubo T, Kanaseki T, Tsukahara T, Nakatsugawa M, Hashimoto S, Osanai M, Torigoe T, Takemasa I
    • Journal Title

      Cancer Sci.

      Volume: 114 Issue: 12 Pages: 4511-4520

    • DOI

      10.1111/cas.15986

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K27387
  • [Journal Article] Cisplatin-induced HSF1-HSP90 axis enhances the expression of functional PD-L1 in oral squamous cell carcinoma2023

    • Author(s)
      Sasaya T, Kubo T, Murata K, Mizue Y, Sasaki K, Yanagawa J, Imagawa M, Kato H, Tsukahara T, Kanaseki T, Tamura Y, Miyazaki A, Hirohashi Y, Torigoe T.
    • Journal Title

      Cancer Med

      Volume: 12 Issue: 4 Pages: 4605-4615

    • DOI

      10.1002/cam4.5310

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-19K10292, KAKENHI-PROJECT-21K18257
  • [Journal Article] SOX10 Inhibits T Cell Recognition by Inducing Expression of the Immune Checkpoint Molecule PD-L1 in A375 Melanoma Cells2023

    • Author(s)
      Sasaki K, Hirohashi Y, Murata K, Minowa T, Nakatsugawa M, Murai A, Mizue Y, Kubo T, Kanaseki T, Tsukahara T, Iwabuchi S, Hashimoto S, Uhara H, Ishida-Yamamoto A, Torigoe T.
    • Journal Title

      Anticancer Res

      Volume: 43 Issue: 4 Pages: 1477-1484

    • DOI

      10.21873/anticanres.16296

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03460
  • [Journal Article] GRIK2 is a target for bladder cancer stem-like cell-targeting immunotherapy2022

    • Author(s)
      Miyata H, Hirohashi Y, Yamada S, Yanagawa J, Murai A, Hashimoto S, Tokita S, Hori K, Abe T, Kubo T, Tsukahara T, Kanaseki T, Shinohara N, Torigoe T.
    • Journal Title

      Cancer Immunology Immunotherapy

      Volume: 71 Issue: 4 Pages: 795-806

    • DOI

      10.1007/s00262-021-03025-z

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-21K18257
  • [Journal Article] Tumor-infiltrating CD8 + T cells recognize a heterogeneously expressed functional neoantigen in clear cell renal cell carcinoma2022

    • Author(s)
      Matsuki M, Hirohashi Y, Nakatsugawa M, Murai A, Kubo T, Hashimoto S, Tokita S, Murata K, Kanaseki T, Tsukahara T, Nishida S, Tanaka T, Kitamura H, Masumori N, Torigoe T.
    • Journal Title

      Cancer Immunology Immunotherapy

      Volume: 71 Issue: 4 Pages: 905-918

    • DOI

      10.1007/s00262-021-03048-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-21K18257
  • [Journal Article] Identification of characteristic subepithelial surface granulomatosis in immune‐related adverse event‐associated enterocolitis2021

    • Author(s)
      Kubo Terufumi、Hirohashi Yoshihiko、Keira Yoshiko、Akimoto Mayuko、Ikeda Tatsuru、Kikuchi Noriaki、Iwaki Hiroyuki、Kikuchi Tomoki、Obata Masahiko、Morita Rena、Kasai Kiyoshi、Segawa Keiko、Tsukahara Tomohide、Kanaseki Takayuki、Murata Kenji、Kikuchi Yasuhiro、Shinkawa Tomoyo、Hasegawa Tadashi、Torigoe Toshihiko
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 3 Pages: 1320-1325

    • DOI

      10.1111/cas.14773

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K19458, KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-20H03807, KAKENHI-PROJECT-21K18257
  • [Journal Article] Epithelioid granulomatous lesions express abundant programmed death ligand-1 (PD-L1): a discussion of adverse events in anti-PD-1 antibody-based cancer immunotherapy.2021

    • Author(s)
      Kubo T, Hirohashi Y, Tsukahara T, Kanaseki T, Murata K, Hasegawa T, Torigoe T.
    • Journal Title

      Hum Vaccin Immunother.

      Volume: 18 Issue: 7 Pages: 1-3

    • DOI

      10.1080/21645515.2020.1870364

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19458, KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-20H03807, KAKENHI-PROJECT-21K18257
  • [Journal Article] Neuregulin-1-β1 and γ-secretase play a critical role in sphere-formation and cell survival of urothelial carcinoma cancer stem-like cells2021

    • Author(s)
      Matsuki M, Inoue R, Murai A, Kubo T, Hashimoto S, Murata K, Kanaseki T, Tsukahara T, Nishida S, Tanaka T, Kitamura H, Masumori N, Hirohashi Y, Torigoe T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 552 Pages: 128-135

    • DOI

      10.1016/j.bbrc.2021.03.038

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03460, KAKENHI-PROJECT-20H03807, KAKENHI-PROJECT-21K18257
  • [Journal Article] Peptide vaccinations elicited strong immune responses that were reboosted by anti-PD1 therapy in a patient with myxofibrosarcoma2020

    • Author(s)
      Tsukahara, T. Watanabe, K. Murata, K. Takahashi, A. Mizushima, E. Shibayama, Y. Kameshima, H. Hatae, R. Ohno, Y. Kawahara, R. Murai, A. Nakatsugawa, M. Kubo, T. Kanaseki, T. Hirohashi, Y. Terui, T. Asanuma, H. Hasegawa, T. Sato, N. Torigoe, T.
    • Journal Title

      Cancer immunology immunotherapy

      Volume: 69 Issue: 2 Pages: 189-197

    • DOI

      10.1007/s00262-019-02455-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540, KAKENHI-PROJECT-20H03807, KAKENHI-PROJECT-18K19458
  • [Journal Article] Upstream Position of Proline Defines Peptide-HLA Class I Repertoire Formation and CD8(+) T Cell Responses2019

    • Author(s)
      Hongo, A. Kanaseki, T. Tokita, S. Kochin, V. Miyamoto, S. Hashino, Y. Codd, A. Kawai, N. Nakatsugawa, M. Hirohashi, Y. Sato, N. Torigoe, T.
    • Journal Title

      Journal of immunology

      Volume: 202 Issue: 10 Pages: 2849-2855

    • DOI

      10.4049/jimmunol.1900029

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K19458, KAKENHI-PROJECT-17H01540
  • [Journal Article] Osteosarcoma‐initiating cells show high aerobic glycolysis and attenuation of oxidative phosphorylation mediated by LIN28B2019

    • Author(s)
      Mizushima Emi、Tsukahara Tomohide、Emori Makoto、Murata Kenji、Akamatsu Asuka、Shibayama Yuji、Hamada Shuto、Watanabe Yuto、Kaya Mitsunori、Hirohashi Yoshihiko、Kanaseki Takayuki、Nakatsugawa Munehide、Kubo Terufumi、Yamashita Toshihiko、Sato Noriyuki、Torigoe Toshihiko
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 1 Pages: 36-46

    • DOI

      10.1111/cas.14229

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10974, KAKENHI-PROJECT-17H01540, KAKENHI-PROJECT-20H03807
  • [Journal Article] Clonal analysis revealed functional heterogeneity in cancer stem-like cell phenotypes in uterine endometrioid adenocarcinoma.2019

    • Author(s)
      Tabuchi Y, Hirohashi Y, Hashimoto S, Mariya T, Asano T, Ikeo K, Kuroda T, Mizuuchi M, Murai A, Uno S, Kawai N, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Saito T, Torigoe T.
    • Journal Title

      Exp Mol Pathol

      Volume: 106 Pages: 78-88

    • DOI

      10.1016/j.yexmp.2018.11.013

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11285, KAKENHI-PLANNED-17H06399, KAKENHI-PROJECT-16H05451, KAKENHI-ORGANIZER-17H06391, KAKENHI-PROJECT-17H01540
  • [Journal Article] Severe cytokine release syndrome resulting in purpura fulminans despite successful response to nivolumab therapy in a patient with pleomorphic carcinoma of the lung: a case report2019

    • Author(s)
      Honjo, O. Kubo, T. Sugaya, F. Nishizaka, T. Kato, K. Hirohashi, Y. Takahashi, H. Torigoe, T.
    • Journal Title

      J Immunother Cancer

      Volume: 7 Issue: 1 Pages: 97-97

    • DOI

      10.1186/s40425-019-0582-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Immunohistological analysis of pancreatic carcinoma after vaccination with survivin 2B peptide: Analysis of an autopsy series.2019

    • Author(s)
      Kubo T, Tsurita G, Hirohashi Y, Yasui H, Ota Y, Watanabe K, Murai A, Matsuo K, Asanuma H, Shima H, Wada S, Nakatsugawa M, Kanaseki T, Tsukahara T, Mizuguchi T, Hirata K, Takemasa I, Imai K, Sato N, Torigoe T.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 8 Pages: 2386-2395

    • DOI

      10.1111/cas.14099

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10672, KAKENHI-PROJECT-17H01540
  • [Journal Article] Randomized phase II trial of survivin 2B peptide vaccination for patients with HLA-A24-positive pancreatic adenocarcinoma.2019

    • Author(s)
      Shima H, Tsurita G, Wada S, Hirohashi Y, Yasui H, Hayashi H, Miyakoshi T, Watanabe K, Murai A, Asanuma H, Tokita S, Kubo T, Nakatsugawa M, Kanaseki T, Tsukahara T, Nakae Y, Sugita O, Ito YM, Ota Y, Kimura Y, Kutomi G, Hirata K, Mizuguchi T, Imai K, Takemasa I, Sato N, Torigoe T.
    • Journal Title

      Cancer Sci.

      Volume: 110 Issue: 8 Pages: 2378-2385

    • DOI

      10.1111/cas.14106

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10672, KAKENHI-PROJECT-17H01540
  • [Journal Article] ABCG2 expression is related to low 5-ALA photodynamic diagnosis (PDD) efficacy and cancer stem cell phenotype, and suppression of ABCG2 improves the efficacy of PDD2019

    • Author(s)
      Kawai Noriko、Hirohashi Yoshihiko、Ebihara Yuma、Saito Takuma、Murai Aiko、Saito Takahiro、Shirosaki Tomohide、Kubo Terufumi、Nakatsugawa Munehide、Kanaseki Takayuki、Tsukahara Tomohide、Shichinohe Toshiaki、Li Liming、Hirano Satoshi、Torigoe Toshihiko
    • Journal Title

      PLOS ONE

      Volume: 14 Issue: 5 Pages: 0216503-0216503

    • DOI

      10.1371/journal.pone.0216503

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K11285, KAKENHI-PROJECT-19K16822, KAKENHI-PROJECT-17H01540
  • [Journal Article] The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy of Colorectal Cancer2018

    • Author(s)
      Miyamoto Sho、Kochin Vitaly、Kanaseki Takayuki、Hongo Ayumi、Tokita Serina、Kikuchi Yasuhiro、Takaya Akari、Hirohashi Yoshihiko、Tsukahara Tomohide、Terui Takeshi、Ishitani Kunihiko、Hata Fumitake、Takemasa Ichiro、Miyazaki Akihiro、Hiratsuka Hiroyoshi、Sato Noriyuki、Torigoe Toshihiko
    • Journal Title

      Cancer Immunology Research

      Volume: 6 Issue: 3 Pages: 358-369

    • DOI

      10.1158/2326-6066.cir-17-0518

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K11729, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
  • [Journal Article] Development of a T-cell receptor multimer with high avidity for detecting a naturally presented tumor-associated antigen on osteosarcoma cells2018

    • Author(s)
      Watanabe Kazue、Tsukahara Tomohide、Toji Shingo、Saitoh Shogo、Hirohashi Yoshihiko、Nakatsugawa Munehide、Kubo Terufumi、Kanaseki Takayuki、Kameshima Hidekazu、Terui Takeshi、Sato Noriyuki、Torigoe Toshihiko
    • Journal Title

      Cancer Science

      Volume: 110 Issue: 1 Pages: 40-51

    • DOI

      10.1111/cas.13854

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
  • [Journal Article] Long-term survival of a pancreatic cancer patient immunized with an SVN-2B peptide vaccine.2018

    • Author(s)
      Shima H, Kutomi G, Satomi F, Imamura M, Kimura Y, Mizuguchi T, Watanabe K, Takahashi A, Murai A, Tsukahara T, Kanaseki T, Hirohashi Y, Iwayama Y, Tsuruma T, Kameshima H, Sato N, Torigoe T, Takemasa I.
    • Journal Title

      Cancer Immunol Immunother.

      Volume: 67 Issue: 10 Pages: 1603-1609

    • DOI

      10.1007/s00262-018-2217-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K10672, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
  • [Journal Article] Influence of PD-L1 expression in immune cells on the response to radiation therapy in patients with oropharyngeal squamous cell carcinoma2018

    • Author(s)
      Fukushima Yuki、Someya Masanori、Nakata Kensei、Hori Masakazu、Kitagawa Mio、Hasegawa Tomokazu、Tsuchiya Takaaki、Gocho Toshio、Ikeda Hikaru、Hirohashi Yoshihiko、Torigoe Toshihiko、Sugita Shintaro、Hasegawa Tadashi、Himi Tetsuo、Sakata Koh-ichi
    • Journal Title

      Radiotherapy and Oncology

      Volume: 129 Issue: 2 Pages: 409-414

    • DOI

      10.1016/j.radonc.2018.08.023

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K07760, KAKENHI-PROJECT-18K15555, KAKENHI-PROJECT-17K16466, KAKENHI-PROJECT-17H01540
  • [Journal Article] Cellular stress induces cancer stem-like cells through expression of DNAJB8 by activation of heat shock factor 12018

    • Author(s)
      Kusumoto Hiroki、Hirohashi Yoshihiko、Nishizawa Satoshi、Yamashita Masamichi、Yasuda Kazuyo、Murai Aiko、Takaya Akari、Mori Takashi、Kubo Terufumi、Nakatsugawa Munehide、Kanaseki Takayuki、Tsukahara Tomohide、Kondo Toru、Sato Noriyuki、Hara Isao、Torigoe Toshihiko
    • Journal Title

      Cancer Science

      Volume: 109 Issue: 3 Pages: 741-750

    • DOI

      10.1111/cas.13501

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-15K10606, KAKENHI-PROJECT-17H01540
  • [Journal Article] Differential bronchial epithelial response regulated by ΔNp63: a functional understanding of the epithelial shedding found in asthma2018

    • Author(s)
      Kubo Terufumi、Tsujiwaki Mitsuhiro、Hirohashi Yoshihiko、Tsukahara Tomohide、Kanaseki Takayuki、Nakatsugawa Munehide、Hasegawa Tadashi、Torigoe Toshihiko
    • Journal Title

      Laboratory Investigation

      Volume: 99 Issue: 2 Pages: 158-168

    • DOI

      10.1038/s41374-018-0132-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-16K21249, KAKENHI-PROJECT-17H01540
  • [Journal Article] Comprehensive single-cell transcriptome analysis reveals heterogeneity in endometrioid adenocarcinoma tissues.2017

    • Author(s)
      Hashimoto S, Tabuchi Y, Yurino H, Hirohashi Y, Deshimaru S, Asano T, Mariya T, Oshima K, Takamura Y, Ukita Y, Ametani A, Kondo N, Monma N, Takeda T, Misu S, Okayama T, Ikeo K, Saito T, Kaneko S, Suzuki Y, Hattori M, Matsushima K, et al.
    • Journal Title

      Sci Rep

      Volume: 7 Issue: 1 Pages: 14225-14225

    • DOI

      10.1038/s41598-017-14676-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K19546, KAKENHI-PLANNED-17H06392, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05203, KAKENHI-PROJECT-17H01540
  • [Journal Article] Phosphorylation of HSF1 at serine 326 residue is related to the maintenance of gynecologic cancer stem cells through expression of HSP272017

    • Author(s)
      Yasuda, K. Hirohashi, Y. Mariya, T. Murai, A. Tabuchi, Y. Kuroda, T. Kusumoto, H. Takaya, A. Yamamoto, E. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Tamura, Y. Hirano, H. Hasegawa, T. Saito, T. Sato, N. Torigoe, T.
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 19 Pages: 31540-31553

    • DOI

      10.18632/oncotarget.16361

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Induction and Analysis of Cytotoxic T-Lymphocytes that Recognize Autologous Oral Squamous Cell Carcinoma2017

    • Author(s)
      Okamoto, J. Y. Miyazaki, A. Kobayashi, J. I. Miyamoto, S. Sasaki, T. Kanaseki, T. Hirohashi, Y. Torigoe, T. Hiratsuka, H.
    • Journal Title

      Anticancer Res

      Volume: 37 Issue: 9 Pages: 4889-4897

    • DOI

      10.21873/anticanres.11898

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Identification of cancer-stem cell antigens and development of CTL-mediated cancer immunotherapy2017

    • Author(s)
      Miyamoto, S. Kanaseki, T. Hirohashi, Y. Tsukahara, T. Kikuchi, Y. Sato, N. Torigoe, T.
    • Journal Title

      Japanese Journal of Clinical Immunology

      Volume: 40 Issue: 1 Pages: 40-47

    • DOI

      10.2177/jsci.40.40

    • NAID

      130005665568

    • ISSN
      0911-4300, 1349-7413
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Implication of chemo-resistant memory T cells for immune surveillance in patients with sarcoma receiving chemotherapy.2017

    • Author(s)
      Shibayama Y, Tsukahara T, Emori M, Murata K, Mizushima E, Hirohashi Y, Kanaseki T, Nakatsugawa M, Kubo T, Yamashita T, Sato N, Torigoe T
    • Journal Title

      Cancer Science

      Volume: 108 Issue: 9 Pages: 1739-1745

    • DOI

      10.1111/cas.13319

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10974, KAKENHI-PROJECT-17H01540
  • [Journal Article] Mismatch Repair Protein Deficiency Is a Risk Factor for Aberrant Expression of HLA Class I Molecules: A Putative "Adaptive Immune Escape" Phenomenon2017

    • Author(s)
      Kubo, T. Hirohashi, Y. Matsuo, K. Sonoda, T. Sakamoto, H. Furumura, K. Tsukahara, T. Kanaseki, T. Nakatsugawa, M. Hirano, H. Furuhata, T. Takemasa, I. Hasegawa, T. Torigoe, T.
    • Journal Title

      Anticancer Res

      Volume: 37 Issue: 3 Pages: 1289-1295

    • DOI

      10.21873/anticanres.11446

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] HLA-A24 ligandome analysis of colon and lung cancer cells identifies a novel cancer-testis antigen and a neoantigen that elicits specific and strong CTL responses.2017

    • Author(s)
      Kochin V, Kanaseki T, Tokita S, Miyamoto S, Shionoya Yo, Kikuchi Y, Morooka D, Hirohashi Y, Tsukahara T, Watanabe K, Toji S, Kokai Y, Sato N, Torigoe T.
    • Journal Title

      Oncoimmunology

      Volume: 6 Issue: 4 Pages: 1-12

    • DOI

      10.1080/2162402x.2017.1293214

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08743, KAKENHI-PROJECT-17H01540
  • [Journal Article] Identification of antigenic peptides from novel renal cancer stem-like cell antigen, DNAJB82017

    • Author(s)
      Nishizawa S, Hirohashi Y, Kusumoto H, Wakamiya T, Iguchi T, Yamashita S, Iba A, Kikkawa K, Kohjimoto Y, Torigoe T, Hara I
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 494 Issue: 3-4 Pages: 693-699

    • DOI

      10.1016/j.bbrc.2017.10.146

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10606, KAKENHI-PROJECT-17K16811, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-17H01540
  • [Journal Article] Cancer-associated oxidoreductase ERO1-α promotes immune escape through up-regulation of PD-L1 in human breast cancer.2017

    • Author(s)
      Tanaka T, Kutomi G, Kajiwara T, Kukita K, Kochin V, Kanaseki T, Tsukahara T, Hirohashi Y, Torigoe T, Okamoto Y, Hirata K, Sato N, Tamura Y.
    • Journal Title

      Oncotarget

      Volume: 2016 Issue: 15 Pages: 24706-24718

    • DOI

      10.18632/oncotarget.14960

    • NAID

      120006219870

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-17H01540
  • [Journal Article] ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.2017

    • Author(s)
      Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y, Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T.
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 68 Pages: 112550-112564

    • DOI

      10.18632/oncotarget.22545

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10672, KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-15K08413, KAKENHI-PROJECT-26462013
  • [Journal Article] Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is a novel target of lung cancer stem-like cell immunotherapy2017

    • Author(s)
      Horibe, R. Hirohashi, Y. Asano, T. Mariya, T. Suzuki, T. Takaya, A. Saijo, H. Shionoya, Y. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Watanabe, K. Atsuyama, E. Toji, S. Hirano, H. Hasegawa, T. Takahashi, H. Sato, N. Torigoe, T.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 3 Pages: 0171460-0171460

    • DOI

      10.1371/journal.pone.0171460

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Identification and functional analysis of variants of a cancer/testis antigen LEMD1 in colorectal cancer stem-like cells2017

    • Author(s)
      Takeda, R. Hirohashi, Y. Shen, M. Wang, L. Ogawa, T. Murai, A. Yamamoto, E. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Nishidate, T. Okita, K. Kutomi, G. Sato, N. Takemasa, I. Torigoe, T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 485 Issue: 3 Pages: 651-657

    • DOI

      10.1016/j.bbrc.2017.02.081

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] Loss of tapasin in human lung and colon cancer cells and escape from tumor-associated antigen- specific CTL recognition2017

    • Author(s)
      Yosuke Shionoya, Takayuki Kanaseki, Sho Miyamoto, et al.
    • Journal Title

      Oncoimmunology

      Volume: 6 Issue: 2 Pages: 1274476-1274476

    • DOI

      10.1080/2162402x.2016.1274476

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26460581, KAKENHI-PROJECT-17H01540
  • [Journal Article] LY6/PLAUR domain containing 3 has a role in the maintenance of colorectal cancer stem-like cells2017

    • Author(s)
      Wang, L. Hirohashi, Y. Ogawa, T. Shen, M. Takeda, R. Murai, A. Yamamoto, E. Kubo, T. Nakatsugawa, M. Kanaseki, T. Tsukahara, T. Nishidate, T. Okita, K. Kutomi, G. Sato, N. Takemasa, I. Torigoe, T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 486 Issue: 2 Pages: 232-238

    • DOI

      10.1016/j.bbrc.2017.02.112

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Journal Article] GRIK2 has a role in the maintenance of urothelial carcinoma stem-like cells, and its expression is associated with poorer prognosis2017

    • Author(s)
      Inoue Ryuta、Hirohashi Yoshihiko、Kitamura Hiroshi、Nishida Sachiyo、Murai Aiko、Takaya Akari、Yamamoto Eri、Matsuki Masahiro、Tanaka Toshiaki、Kubo Terufumi、Nakatsugawa Munehide、Kanaseki Takayuki、Tsukahara Tomohide、Sato Noriyuki、Masumori Naoya、Torigoe Toshihiko
    • Journal Title

      Oncotarget

      Volume: 8 Issue: 17 Pages: 28826-28839

    • DOI

      10.18632/oncotarget.16259

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K10599, KAKENHI-PROJECT-17H01540
  • [Journal Article] Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is involved in cervical cancer stemness and can be a target of immunotherapy.2016

    • Author(s)
      Asano T, Hirohashi Y, Torigoe T, Mariya T, Horibe R, Kuroda T, Tabuchi Y, Saijo H, Yasuda K, Mizuuchi M, Takahashi A, Asanuma H, Hasegawa T, Saito T, Sato N.
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 10 Pages: 11223-11237

    • DOI

      10.18632/oncotarget.7165

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-25462599
  • [Journal Article] Immune responses to human cancer stem-like cells/cancer-initiating cells.2016

    • Author(s)
      Hirohashi Y, Torigoe T, Tsukahara T, Kanaseki T, Kochin V, Sato N
    • Journal Title

      Cancer Sci

      Volume: 107 Issue: 1 Pages: 12-17

    • DOI

      10.1111/cas.12830

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Journal Article] Plasticity of lung cancer stem-like cells is regulated by the transcription factor HOXA5 that is induced by oxidative stress2016

    • Author(s)
      Hiroshi Saijo, Yoshihiko Hirohashi, et al.
    • Journal Title

      Oncotarget

      Volume: 2;7(31) Issue: 31 Pages: 50043-50056

    • DOI

      10.18632/oncotarget.10571

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-16K07122, KAKENHI-PROJECT-26460944
  • [Journal Article] MAPK13 is preferentially expressed in gynecological cancer stem cells and has a role in the tumor-initiation.2016

    • Author(s)
      Yasuda K, Hirohashi Y, Kuroda T, Takaya A, Kubo T, Kanaseki T, Tsukahara T, Hasegawa T, Saito T, Sato N, Torigoe T.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 472 Issue: 4 Pages: 643-647

    • DOI

      10.1016/j.bbrc.2016.03.004

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Journal Article] Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer-Initiating Cells and Is a Potent Target of Immunotherapy2016

    • Author(s)
      Rena Morita, Yoshihiko Hirohashi, et al.
    • Journal Title

      Clinical Cancer Research

      Volume: 1;22(13) Issue: 13 Pages: 3298-308

    • DOI

      10.1158/1078-0432.ccr-15-1709

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-26461921, KAKENHI-PROJECT-26860239
  • [Journal Article] Establishment and analysis of cancer stem-like and non-cancer stem-like cells from the human colon cancer cell line SW4802016

    • Author(s)
      Akari Takaya, Yoshihiko Hirohashi, et al.
    • Journal Title

      PLOS One

      Volume: 14;11(7) Issue: 7 Pages: e0158903-e0158903

    • DOI

      10.1371/journal.pone.0158903

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04722, KAKENHI-PROJECT-16H05451, KAKENHI-PROJECT-26860239
  • [Journal Article] Matrix metalloproteinase-10 regulates stemness of ovarian cancer stem-like cells by activation of canonical Wnt signaling and can be a target of chemotherapy-resistant ovarian cancer.2016

    • Author(s)
      Mariya T, Hirohashi Y, Torigoe T, Tabuchi Y, Asano T, Saijo H, Kuroda T, Yasuda K, Mizuuchi M, Saito T, Sato N
    • Journal Title

      Oncotarget

      Volume: in press Issue: 18 Pages: 1-17

    • DOI

      10.18632/oncotarget.8645

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Journal Article] Olfactory receptor family receptor, family 7, subfamily C, member 1 is a novel marker of colon cancer-initiating cells and is a potent target of immunotherapy.2016

    • Author(s)
      Morita R, Hirohashi Y, Torigoe T, Inoda S, Takahashi A, Mariya T, Asanuma H, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Kutomi G, Mizuguchi T, Terui T, Ishitani K, Hashino S, Kondo T, Minagawa N, Takahashi N, Taketomi A, Todo S, Asaka M, Sato N.
    • Journal Title

      Clin Cancer Res

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Journal Article] Phase I Clinical Study of Survivin-Derived Peptide Vaccine for Patients with Advanced Gastrointestinal Cancers.2015

    • Author(s)
      Satomi F, Shima H, Mizuguchi T, Torigoe T, Kutomi G, Kimura Y, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Takahashi A, Asanuma H, Ito Y, Hayashi H, Sugita O, Sato N and Hirata K.
    • Journal Title

      Int J Cancer Clin Res

      Volume: 2

    • NAID

      40020774852

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Trials of vaccines for pancreatic ductal adenocarcinoma: Is there any hope of an improved prognosis?2015

    • Author(s)
      Mizuguchi T, Torigoe T, Satomi F, Shima H, Kutomi G, Ota S, Ishii M, Hayashi H, Asakura S, Hirohashi Y, Meguro M, Kimura Y, Nishidate T, Okita K, Ishino M, Miyamoto A, Hatakenaka M, Sato N, Hirata K.
    • Journal Title

      Surg Today

      Volume: in press Issue: 2 Pages: 139-148

    • DOI

      10.1007/s00595-015-1120-8

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Expression of hepatocyte growth factor in prostate cancer may indicate a biochemical recurrence after radical prostatectomy.2015

    • Author(s)
      Nishida S, Hirohashi Y, Torigoe T, Nojima M, Inoue R, Kitamura H, Tanaka T, Asanuma H, Sato N, Masumori N.
    • Journal Title

      Anticancer Res

      Volume: 35 Pages: 413-8

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Journal Article] Expression of hepatocyte growth factor in prostate cancer may indicate a biochemical recurrence after radical prostatectomy.2015

    • Author(s)
      Nishida S, Hirohashi Y, Torigoe T., Nojima M, Inoue R, Kitamura H, Tanaka T, Asanuma H, Sato N, Masumori N.
    • Journal Title

      Anticancer Res

      Volume: 35 Pages: 413-418

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity.2014

    • Author(s)
      Yasuda K, Torigoe T, Mariya T, Asano T, Kuroda T, Matsuzaki J, Ikeda K, Yamauchi M, Emori M, Asanuma H, Hasegawa T, Saito T, Hirohashi Y, Sato N.
    • Journal Title

      Lab Invest

      Volume: 94 Issue: 12 Pages: 1355-69

    • DOI

      10.1038/labinvest.2014.122

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
  • [Journal Article] Prognostic impact of human leukocyte antigen class I expression and association of platinum resistance with immunologic profiles in epithelial ovarian cancer.2014

    • Author(s)
      Mariya T, Hirohashi Y, Torigoe T, Asano T, Kuroda T, Yasuda K, Mizuuchi M, Sonoda T, Saito T, Sato N.
    • Journal Title

      Cancer Immunol Res

      Volume: 2 Issue: 12 Pages: 1220-9

    • DOI

      10.1158/2326-6066.cir-14-0101

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165
  • [Journal Article] Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.2014

    • Author(s)
      Morita R, Nishizawa S, Torigoe T, Takahashi A, Tamura Y, Tsukahara T, Kanaseki T, Sokolovskaya A, Kochin V, Kondo T, Hashino S, Asaka M, Hara I, Hirohashi Y, Sato N.
    • Journal Title

      Cancer Sci

      Volume: 105 Issue: 4 Pages: 389-395

    • DOI

      10.1111/cas.12362

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
  • [Journal Article] Production of multiple CTL epitopes from multiple tumor-associated antigens.2014

    • Author(s)
      Morita R, Hirohashi Y, Nakatsugawa M, Kanaseki T, Torigoe T, Sato N.
    • Journal Title

      Methods Mol Biol

      Volume: 1139 Pages: 345-55

    • DOI

      10.1007/978-1-4939-0345-0_28

    • ISBN
      9781493903443, 9781493903450
    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165
  • [Journal Article] Prognostic impact of human leukocyte antigen class I expression and association of platinum resistance with immunologic profiles in epithelial ovarian cancer.2014

    • Author(s)
      Mariya T, Hirohashi Y, Torigoe T., Asano T, Kuroda T, Yasuda K, Mizuuchi M, Sonoda T, Saito T, Sato N
    • Journal Title

      Cancer Immunol Res

      Volume: 2 Pages: 1220-1229

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Expression and function of FERMT genes in colon carcinoma cells.2013

    • Author(s)
      Kiriyama K, Hirohashi Y, Torigoe T, Kubo T, Tamura Y, Kanaseki T, Takahashi A, Nakazawa E, Saka E, Ragnarsson C, Nakatsugawa M, Inoda S, Asanuma H, Takasu H, Hasegawa T, Yasoshima T, Hirata K, Sato N
    • Journal Title

      Anticancer Res

      Volume: 33 Pages: 167-73

    • Data Source
      KAKENHI-PROJECT-24659592
  • [Journal Article] Expression and function of FERMT genes in colon carcinoma cells2013

    • Author(s)
      Kiriyama K, Hirohashi Y, Torigoe T, et al.
    • Journal Title

      Anticancer Res

      Volume: 33 Pages: 167-73

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Journal Article] Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.2013

    • Author(s)
      Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.
    • Journal Title

      Biochem Biophys Res Commun

      Volume: 439 Issue: 1 Pages: 96-102

    • DOI

      10.1016/j.bbrc.2013.08.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659901, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-24792005, KAKENHI-PROJECT-25462344, KAKENHI-PROJECT-25463115
  • [Journal Article] Immunotherapeutic benefit ofα-interferon (IFNα) in survivin2B-derived peptide vaccination for advanced pancreatic cancer patients2013

    • Author(s)
      Kameshima H, Tsuruma T, Kutomi G, Shima H, Iwayama Y, Kimura Y, Imamura M, Torigoe T, Takahashi A, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Sato N, Hirata K
    • Journal Title

      Cancer Sci.

      Volume: 104 Issue: 1 Pages: 124-129

    • DOI

      10.1111/cas.12046

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592
  • [Journal Article] Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.2013

    • Author(s)
      Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J, Kochin V, Asanuma H, Hasegawa T, Saito T, Hirohashi Y, Sato N.
    • Journal Title

      PLoS One

      Volume: 8(8) Issue: 8 Pages: e68187-e68187

    • DOI

      10.1371/journal.pone.0068187

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
  • [Journal Article] Preferential expression of cancer/testis genes in cancer stem-like cells : proposal of a novel sub-category, cancer/testis/stem gene.2013

    • Author(s)
      Yamada R, Takahashi A, Torigoe T, Morita R, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Watarai K, Kondo T, Hirohashi Y, Sato N.
    • Journal Title

      Tissue Antigens.

      Volume: 81(6) Issue: 6 Pages: 428-34

    • DOI

      10.1111/tan.12113

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
  • [Journal Article] Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor.2013

    • Author(s)
      Nishida S, Hirohashi Y, Torigoe T, Inoue R, Kitamura H, Tanaka T, Takahashi A, Asanuma H, Masumori N, Tsukamoto T, Sato N.
    • Journal Title

      Cancer Sci

      Volume: 104 Issue: 4 Pages: 431-6

    • DOI

      10.1111/cas.12104

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24592399, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-221S0001
  • [Journal Article] DNA methyltransferase 1 is essential for initiation of the colon cancers2013

    • Author(s)
      Morita R,Hirohashi Y,Suzuki H, et al
    • Journal Title

      Experimental and Molecular Pathology

      Volume: 94 Issue: 2 Pages: 322-329

    • DOI

      10.1016/j.yexmp.2012.10.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115
  • [Journal Article] Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells.2013

    • Author(s)
      Takahashi A, Hirohashi Y, Torigoe T, Tamura Y, Tsukahara T, Kanaseki T, Kochin V, Saijo H, Kubo T, Nakatsugawa M, Asanuma H, Hasegawa T, Kondo T, Sato N.
    • Journal Title

      PLoS One

      Volume: 8 Issue: 11 Pages: e69095-e69095

    • DOI

      10.1371/journal.pone.0069095

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
  • [Journal Article] Novel oligomannose liposome-DNA complex DNA vaccination efficiently evokes anti-HPV E6 and E7 CTL responses2012

    • Author(s)
      Mizuuchi M, Hirohashi Y, Torigoe T, Takafumi K, Yasuda K, Saito T, Sato N
    • Journal Title

      Exp Mol Pathol.

      Volume: 92 Issue: 1 Pages: 185-190

    • DOI

      10.1016/j.yexmp.2011.10.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-21592141
  • [Journal Article] Novel oligomannose liposome-DNA complex DNA vaccination efficiently evokes anti-HPV E6 and E7 CTL responses2012

    • Author(s)
      Mizuuchi M, Hirohashi Y, Torigoe T, Takafumi K, Yasuda K, Saito T, Sato N.
    • Journal Title

      Exp Mol Pathol

      Volume: 92 Pages: 185-190

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2011.10.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] ECRG4 is a negative regulator of caspase-8-mediated apoptosis in human T-leukemia cells2012

    • Author(s)
      Matsuzaki J,Torigoe T,Hirohashi Y, Kamiguchi K,Tamura Y, Tsukahara T,Kubo T, Takahashi A, Nakazawa E,Saka E, Yasuda K,Takahashi S,Sato N.
    • Journal Title

      Carcinogenesis

      Volume: 33 Issue: 5 Pages: 996-1003

    • DOI

      10.1093/carcin/bgs118

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J06539, KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22689041, KAKENHI-PROJECT-23590427
  • [Journal Article] Heat shock protein 40 family, DNAJB8 is expressed in renal cancer stem-like cell, controls the tumor-initiating ability and can be a potent target of immunotherapy.2012

    • Author(s)
      Nishizawa, S., Mori, T., Hirohashi, Y., Torigoe, T., Tamura, Y., Kamiguchi, K., Takahashi, A., Kanaseki, T., Nakazawa, E., Asanuma, H., Sokolovskaya, A., Morita, R., Yamada, R., Fujii, R., Kondo, T., Hasegawa, T., Hara, I. and Sato, N.
    • Journal Title

      Cancer Res

      Volume: (in press) Issue: 11 Pages: 2844-54

    • DOI

      10.1158/0008-5472.can-11-3062

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659165
  • [Journal Article] Depletion of Tregs in vivo: a promising approach to enhance antitumor immunity without autoimmunity2012

    • Author(s)
      Morita R,Hirohashi Y,Sato N.
    • Journal Title

      Immunotherapy

      Volume: 4 Issue: 11 Pages: 1103-1105

    • DOI

      10.2217/imt.12.116

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24590449
  • [Journal Article] Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes2012

    • Author(s)
      Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, Kameshima H, Tsuruma T, Hirata K, Tokino T, Hirohashi Y, Sato N
    • Journal Title

      Cell Stress Chaperones

      Volume: 17 Issue: 6 Pages: 757-763

    • DOI

      10.1007/s12192-012-0348-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467
  • [Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012

    • Author(s)
      Mori T, Nishizawa S, Hirohashi Y, Torigoe T, Tamura Y, Takahashi A, Kochin V, Fujii R, Toru K, Greene MI, Hara I, Sato N.
    • Journal Title

      Exp Mol Pathol

      Volume: 92 Pages: 27-32

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2011.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Establishment of a monoclonal anti-pan HLA class I antibody suitable for immunostaining of formalin-fixed tissue : Unusually high frequency of down-regulation in breast cancer tissues2012

    • Author(s)
      Torigoe, T., Asanuma, H., Nakazawa. E., Tamura, Y., Hirohashi, Y., Yamamoto, E., Kanaseki, T., Hasegawa, T., Sato, N.
    • Journal Title

      Pathol Int

      Volume: 62 Issue: 5 Pages: 303-8

    • DOI

      10.1111/j.1440-1827.2012.02789.x

    • NAID

      10031185205

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659592
  • [Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012

    • Author(s)
      Mori T, Nishizawa S, Hirohashi Y, Torigoe T, Tamura Y, Takahashi A, Kochin V, Fujii R, Toru K, Greene MI, Hara I, Sato N
    • Journal Title

      Exp Mol Pathol

      Volume: 92 Pages: 27-32

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2011.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Efficiency of G2/M-related tumor-associated antigen-targeting cancer immunotherapy depends on antigen expression in the cancer stem-like population2012

    • Author(s)
      Takashi Mori, Satoshi Nishizawa, Yoshihiko Hirohashi, Toshihiko Torigoe, Yasuaki Tamura, Akari Takahashi, Vitaly Kochin, Reona Fujii, Kondo Toru, Mark I. Greene, Isao Hara, Noriyuki Sato
    • Journal Title

      Experimental and Molecular Pathology

      Volume: 92 Issue: 1 Pages: 27-32

    • DOI

      10.1016/j.yexmp.2011.09.016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-10F00121, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24659592
  • [Journal Article] The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma2011

    • Author(s)
      Inoda S, Morita R, Hirohashi Y, Torigoe T, Asanuma H, Nakazawa E, Nakatsugawa M, Tamura Y, Kamiguchi K, Tsuruma T, Terui T, Ishitani K, Hashino S, Wang Q, Greene MI, Hasegawa T, Hirata K, Asaka M, Sato N.
    • Journal Title

      Exp. Mol. Pathol

      Volume: 90 Pages: 55-60

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2010.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Phase I clinical trial of survivin-derived peptide vaccine therapy for patients with advanced or recurrent oral cancer2011

    • Author(s)
      Miyazaki A, Kobayashi J, Torigoe T, Hirohashi Y, Yamamoto T, Yamaguchi A, Asanuma H, Takahashi A, Michifuri Y, Nakamori K, Nagai I, Sato N, Hiratsuka H.
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 2 Pages: 324-329

    • DOI

      10.1111/j.1349-7006.2010.01789.x

    • NAID

      10029289826

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22390388, KAKENHI-PROJECT-22592242, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235
  • [Journal Article] Tumor-Produced Secreted Form of Binding of Immunoglobulin Protein Elicits Antigen-Specific Tumor Immunity.2011

    • Author(s)
      Tamura Y, Hirohashi Y, Kutomi G, Nakanishi K, Kamiguchi K, Torigoe T, Sato N.
    • Journal Title

      J. Immunol

      Volume: 186 Issue: 7 Pages: 4325-4330

    • DOI

      10.4049/jimmunol.1004048

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590400, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
  • [Journal Article] Cytotixic T lymphocytes efficiently recognize human colon cancer stem-like cells2011

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Morita, R., Nakatsugawa, M., Nishizawa, S., Tamura, Y., Tsuruma, T., Terui, T., Ishitani, K., Hirata, K. and Sato, N.
    • Journal Title

      Am. J. Pathol

      Volume: 178 Pages: 1805-1813

    • URL

      http://dx.doi.org/10.1016/j.ajpath.2011.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Immunogenic enhancement and clinical effect by type-I interferon of anti-apoptotic protein, survivin-derived peptide vaccine, in advanced colorectal cancer patients2011

    • Author(s)
      Kameshima, H., Tsuruma, T., Torigoe, T., Takahashi, A., Hirohashi, Y., Tamura, Y., Tsukahara, T., Ichimiya, S., Kanaseki, T., Iwayama, Y., Sato, N., Hirata, K.
    • Journal Title

      Cancer Sci

      Volume: 102 Issue: 6 Pages: 1181-1187

    • DOI

      10.1111/j.1349-7006.2011.01918.x

    • NAID

      10029294487

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-22689041, KAKENHI-PROJECT-23590405, KAKENHI-PROJECT-23590427
  • [Journal Article] Autoantibody against hypoxia-inducible factor prolyl hydroxylase-3 is a potential serological marker for renal cell carcinoma2011

    • Author(s)
      Tanaka, T., Kitamura, H., Torigoe, T., Hirohashi, Y., Masumori, N., Sato, N. and Tsukamoto, T.
    • Journal Title

      J. Cancer Res. Clin. Oncol

      Volume: 137 Issue: 5 Pages: 789-794

    • DOI

      10.1007/s00432-010-0940-6

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-22791477
  • [Journal Article] SOX2 is expressed in stem-like cells of human lung adenocarcinoma and augments the tumor-initiating potential2011

    • Author(s)
      Nakatsugawa, M., Takahashi, A., Hirohashi, Y., Torigoe, T., Inoda, S., Asanuma, H., Tamura, Y., Hasegawa, T., Takahashi, H., and Sato, N.
    • Journal Title

      Lab Invest.

      Volume: 91 Issue: 12 Pages: 1796-1804

    • DOI

      10.1038/labinvest.2011.140

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
  • [Journal Article] Tumor associated dendritic cells : molecular mechanisms to suppress anti-tumor immunity2011

    • Author(s)
      Hirohashi, Y. and Sato, N.
    • Journal Title

      Immunotherapy

      Volume: 3 Issue: 8 Pages: 945-947

    • DOI

      10.2217/imt.11.94

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235
  • [Journal Article] Cytotixic T lymphocytes efficiently recognize human colon cancer stem-like cells2011

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Takahashi, A., Morita, R., Nakatsugawa, M., Nishizawa, S., Tamura, Y., Tsuruma, T., Terui, T., Ishitani, K., Hirata, K. and Sato, N.
    • Journal Title

      Am. J. Pathol.

      Volume: 178 Issue: 4 Pages: 1805-1813

    • DOI

      10.1016/j.ajpath.2011.01.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22390278, KAKENHI-PROJECT-23590427
  • [Journal Article] Comparison of speedy PCR-ssp method and serological typing of hla-a24 for Japanese cancer patients.2011

    • Author(s)
      Nakatsugawa M, Hirohashi Y, Torigoe T, Inoda S, Kiriyama K, Tamura Y, Sato E, Takahashi H, Sato N.
    • Journal Title

      J Immunoassay Immunochem

      Volume: 32 Issue: 2 Pages: 93-102

    • DOI

      10.1080/15321819.2010.543219

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659075, KAKENHI-PROJECT-22659235, KAKENHI-PROJECT-23590427
  • [Journal Article] The feasibility of Cep55/c10orf3 derived peptide vaccine therapy for colorectal carcinoma2011

    • Author(s)
      Inoda S, Morita R, Hirohashi Y, Torigoe T, Asanuma H, Nakazawa E, Nakatsugawa M, Tamura Y, Kamiguchi K, Tsuruma T, Terui T, Ishitani K, Hashino S, Wang Q, Greene MI, Hasegawa T, Hirata K, Asaka M, Sato N.
    • Journal Title

      Exp. Mol. Pathol.

      Volume: 90 Issue: 1 Pages: 55-60

    • DOI

      10.1016/j.yexmp.2010.10.001

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401, KAKENHI-PROJECT-22659235
  • [Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells.2010

    • Author(s)
      Hirohashi, Y., Sato, N., et al.
    • Journal Title

      Immunotherapy

      Volume: 2 Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010

    • Author(s)
      Hirohashi, Y., Torigoe, T., Inoda, S., Takahashi, A., Morita, R., Nishizawa, S., Tamura, Y., Suzuki, H., Yoyota, M. Sato, N.
    • Journal Title

      Immunotherapy

      Volume: 2 Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells2010

    • Author(s)
      廣橋良彦, et al
    • Journal Title

      Exp Mol Pathol. 88

      Pages: 128-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010

    • Author(s)
      Hirohashi, Y., Torigoe, T., Inoda, S., Takahashi, A., Morita, R., Nishizawa, S., Tamura, Y., Suzuki, H., Yoyota, M. Sato, N.
    • Journal Title

      Immunotherapy

      Volume: 2 Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Establishment of shared antigen reactive cytotoxic T lymphocyte using co-stimulatory molecule introduced autologous cancer cells. Exp Mol Pathol.2010

    • Author(s)
      Hirohashi, Y., Torigoe, T., et al.
    • Journal Title

      Exp Mol Pathol.

      Volume: 88 Pages: 128-132

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Immune response against tumor antigens expressed on human cancer-stem cells/tumor-initiating cells.2010

    • Author(s)
      Hirohashi Y., Torigoe T., et al.
    • Journal Title

      Immunotherapy

      Volume: 2 Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Immune response against tumor antigens expressed on human cancer-stem cells/tumor-initiating cells2010

    • Author(s)
      廣橋良彦, et al
    • Journal Title

      Immunotherapy 2

      Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Immune response against tumor antigens expressed on human cancer stem-like cells/tumor-initiating cells2010

    • Author(s)
      Hirohashi, Y., et al
    • Journal Title

      Immunotherapy 2

      Pages: 201-211

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Human leukocyte antigen class I down-regulation in muscle-invasive bladder cancer : Its association with clinical characteristics and survival after cystectomy2009

    • Author(s)
      Homma, I., Kitamura, H., Torigoe, T., Tanaka, T., Sato, E., Hirohashi, Y., Masumori, N., Sato, N. and Tsukamoto, T.
    • Journal Title

      Cancer Sci

      Volume: 100 Issue: 12 Pages: 2331-2334

    • DOI

      10.1111/j.1349-7006.2009.01329.x

    • NAID

      10027198144

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer2009

    • Author(s)
      Honma, I., Torigoe, T., Hirohashi, Y., Kitamura, H., Sato, E., Masumori, N., Tamura, Y., Tsukamoto, T., Sato, N.
    • Journal Title

      J. Transl. Med

      Volume: 7 Issue: 1 Pages: 103-110

    • DOI

      10.1186/1479-5876-7-103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Comparative study on the immunogenicity between an HLA-A24-restricted cytotoxic T-cell epitope derived from surviving and that from its splice variant surviving-2B in oral cancer patients2009

    • Author(s)
      Kobayashi, J., Torigoe, T., Hirohashi, Y., Idenoue, S., Miyazaki, A., Yamaguchi, A., Hiratsuka, H. and Sato, N.
    • Journal Title

      J. Transl. Med

      Volume: 7 Issue: 1 Pages: 1-11

    • DOI

      10.1186/1479-5876-7-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] The functioning antigens ; beyond just as the immunologic targets2009

    • Author(s)
      Hirohashi, Y., et al
    • Journal Title

      Cancer Sci 100

      Pages: 798-806

    • NAID

      10025145179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] A novel spliced form of a lens protein as a novel lung cancer antigen2009

    • Author(s)
      Nakatsugawa, M. Hirohashi, Y., Torigoe, T., Asanuma, H., Takahashi, A., Inosa, S., Kiriyama, K., Nakazawa, E., Harada, K., Takasi, H., Tamura, Y., Kamiguchi, K., Shijubo, N., Honda, R., Nomura, N., Hasegawa, T., Takahashi, H. and Sato, N.
    • Journal Title

      Cancer Sci

      Volume: 100 Issue: 8 Pages: 1485-1493

    • DOI

      10.1111/j.1349-7006.2009.01187.x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma2009

    • Author(s)
      Kobayashi, J., Torigoe, T., Hirohashi, Y., Tamura, Y., Kamiguchi, K., Miyazaki, A., Yamaguchi, A., Yamamoto, T., Hariu, H., Hiratsuka, H. and Sato, N.
    • Journal Title

      Hum Immunol

      Volume: 70 Pages: 89-95

    • URL

      http://dx.doi.org/10.1016/j.humimm.2008.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] The functioning antigens ; beyond just as the immunologic targets2009

    • Author(s)
      廣橋良彦, et al
    • Journal Title

      Cancer Sci. 100

      Pages: 798-806

    • NAID

      10025145179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Establishment of shared antigen reactive cytotixic T lymphocytes using co-stimulatory molecule introduced autologous cancer cells2009

    • Author(s)
      Hirohashi, Y., Torigoe, T., Hirai, I., Tamura, Y., Nakatsugawa, M., Inoue, Y., Kanaseki, T., Kamiguchi, K., Ikeda, H., Sasaki, A., Yamanaka, N. and Sato, N.
    • Journal Title

      Exp. Mol. Pathol.

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2009.09.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma2009

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Nakatsugawa, M., Kiriyama, K., Harada, K., Takasu, H., Tamura, Y., Kamiguchi, K., Asanuma, H., Tsuruma, T., Terui, T., Ishitani, K., Ohmura, T., Hasegawa, T., Hirata, K. and Sato, N.
    • Journal Title

      J. Immunother

      Volume: 32 Pages: 474-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] がん幹細胞抗原の検索とがんワクチンへの応用2009

    • Author(s)
      廣橋良彦, 他
    • Journal Title

      最新医学 64

      Pages: 27-36

    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Establishment of shared antigen reactive cytotixic T lymphocytes using co-stimulatory molecule introduced autologous cancer cells2009

    • Author(s)
      Hirohashi, Y., Torigoe, T., Hirai, I., Tamura, Y., Nakatsugawa, M., Inoue, Y., Kanaseki, T., Kamiguchi, K., Ikeda, H., Sasaki, A., Yamanaka, N. and Sato, N.
    • Journal Title

      Exp. Mol. Pathol

    • URL

      http://dx.doi.org/10.1016/j.yexmp.2009.09.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Journal Article] Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen regulated protein 150(ORP150)-peptide complexes2009

    • Author(s)
      Kutomi, G., Tamura, Y., Okuya, K., Hirohashi, Y., Kamiguchi, K., Saito, K., Torigoe, T., Ogawa, S., Hirata, K. and Sato, N.
    • Journal Title

      J. Immunol

      Volume: 183 Issue: 9 Pages: 5861-5869

    • DOI

      10.4049/jimmunol.0803768

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] The functioning antigens ; beyond just as the immunologic targets2009

    • Author(s)
      Hirohashi, Y., Torigoe, T., Inoda, S., Kobayashi, J., Nakatsugawa, M., Mori, T., Hara, I. and Sato, N.
    • Journal Title

      Cancer Sci

      Volume: 100 Issue: 5 Pages: 798-806

    • DOI

      10.1111/j.1349-7006.2009.01137.x

    • NAID

      10025145179

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Cep55/c10orf3, a tumor antigen derived from a centrosome residing protein in breast carcinoma2009

    • Author(s)
      Inoda, S., Hirohashi, Y., Torigoe, T., Nakatsugawa, M., Kiriyama, K., Harada, K., Takasu, H., Tamura, Y., Kamiguchi, K., Asanuma, H., Tsuruma, T., Terui, T., Ishitani, K., Ohmura, T., Hasegawa, T., Hirata, K. and Sato, N.
    • Journal Title

      J. Immunother.

      Volume: 32 Pages: 474-485

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Clonal diversity of cytotoxic T lymphocytes that recognize autologous oral squamous cell carcinoma2009

    • Author(s)
      Kobayashi, J., Torigoe, T., Hirohashi, Y., Tamura, Y., Kamiguchi, K., Miyazaki, A., Yamaguchi, A., Yamamoto, T., Hariu, H., Hiratsuka, H. and Sato, N.
    • Journal Title

      Hum Immunol.

      Volume: 70 Pages: 89-95

    • URL

      http://dx.doi.org/10.1016/j.humimm.2008.11.004

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] Molecular pathologic approaches to human tumor immunology2009

    • Author(s)
      Sato, N., Hirohashi, Y., Tsukahara, T., Kikuchi, T., Sahara, H., Kamiguchi, K., Ichimiya, S., Tamura, H. and Torigoe, T.
    • Journal Title

      Pathol. Int

      Volume: 59 Issue: 4 Pages: 205-217

    • DOI

      10.1111/j.1440-1827.2009.02353.x

    • NAID

      10027379604

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] Phase I clinical study of anti-apoptosis protein survivin-derived peptide vaccination for patients with advanced or recurrent urothelial cancer2009

    • Author(s)
      Honma, I., Kitamura, H., Torigoe, A. Takahashi, T., Tanaka, T., Sato, E., Hirohashi, Y., Masumori, N., Tsukamoto, T., Sato, N.
    • Journal Title

      Cancer Immunol. Immunother

      Volume: 58 Issue: 11 Pages: 1801-1807

    • DOI

      10.1007/s00262-009-0691-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025, KAKENHI-PROJECT-21590401
  • [Journal Article] DNA methyltransferase 1 is essential for maintenance of human colon cancer stem-like cells

    • Author(s)
      Morita, R., Hirohashi, Y., Torigoe, T., Takahashi, A., Saka, E., Asanuma, H., Suzuki, H., Tamura, H., Nakazawa, E., Ito-Inoda, S., Hashino, S., Hasegawa, T., Tokino, T., Toyota, M., Asaka, M. and Sato, N.
    • Journal Title

      Am J. Pathol.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Journal Article] DNA methyltransferase 1 is essential for maintenance of human colon cancer stem-like cells

    • Author(s)
      Morita, R., Hirohashi, Y., Torigoe, T., Takahashi, A., Saka, E., Asanuma, H., Suzuki, H., Tamura, H., Nakazawa, E., Ito-Inoda, S., Hashino, S., Hasegawa, T., Tokino, T., Toyota, M., Asaka, M. and Sato, N.
    • Journal Title

      Am J. Pathol.

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Patent] 抗原特異的T細胞誘導脳測定法2010

    • Inventor(s)
      鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
    • Industrial Property Rights Holder
      鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
    • Filing Date
      2010-08-30
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Patent] SOX2由来のHLA-A24結合性癌抗原ペプチド2010

    • Inventor(s)
      鳥越俊彦、廣橋良彦、中津川宗秀、佐藤昇志、高橋あかり
    • Industrial Property Rights Holder
      北海道公立大学法人札幌医科大学、JST
    • Filing Date
      2010-03-19
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Patent] 抗原特異的T細胞誘導脳測定法2010

    • Inventor(s)
      鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
    • Industrial Property Rights Holder
      鳥越俊彦、廣橋良彦、水内将人、佐藤昇志、鈴木哲、清水佳隆、佐藤雄一郎
    • Filing Date
      2010-08-30
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Patent] サバイビン由来のHLA-A24結合性癌抗原ペプチド2010

    • Inventor(s)
      佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
    • Industrial Property Rights Holder
      佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
    • Industrial Property Number
      2004-191478
    • Filing Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Patent] サバイビン由来のHLA-A 24結合性癌抗原ペプチド2010

    • Inventor(s)
      佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
    • Industrial Property Rights Holder
      佐藤昇志、鳥越俊彦、廣橋良彦、井手之上里美、小林淳一
    • Industrial Property Number
      2004-191478
    • Filing Date
      2010-10-08
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Patent] がん幹細胞分子マーカー2009

    • Inventor(s)
      鳥越俊彦、廣橋良彦、佐藤昇志、上口権二郎、守田玲菜、西澤哲、高橋あかり
    • Industrial Property Rights Holder
      北海道公立大学法人札幌医科大学、大日本住友製薬株式会社
    • Filing Date
      2009-10-27
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Patent] がん幹細胞分子マーカー2009

    • Inventor(s)
      鳥越俊彦, 廣橋良彦, 佐藤昇志, 上口権二郎, 守田玲菜, 西澤哲, 高橋あかり
    • Industrial Property Rights Holder
      鳥越俊彦, 廣橋良彦, 佐藤昇志, 上口権二郎, 守田玲菜, 西澤哲, 高橋あかり
    • Filing Date
      2009-10-27
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Patent] がん幹細胞分子マーカー2009

    • Inventor(s)
      鳥越俊彦、廣橋良彦、佐藤昇志(他4名)
    • Industrial Property Rights Holder
      鳥越俊彦、廣橋良彦、佐藤昇志(他4名)
    • Filing Date
      2009-10-27
    • Overseas
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] 大腸癌の癌関連線維芽細胞とがん幹細胞性の関連におけるPeriostinの役割; 抗Periostin抗体 OC-20を用いたDesmoplastic Reaction分類別の検討2023

    • Author(s)
      安部紘生、梶原由規、望月早月、神藤英二、岡本耕一、阿尾理一、永田健、廣橋良彦、鳥越俊彦、岸庸二、上野秀樹
    • Organizer
      第123回 日本外科学会定期学術集会
    • Data Source
      KAKENHI-PROJECT-23K27678
  • [Presentation] 大腸がん幹細胞における嗅覚受容体OR7C1の機能解析2023

    • Author(s)
      橋本薫、神津凉奈、越澤知世、武井則雄、廣橋良彦、養王田正文、福谷洋介
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-23K26462
  • [Presentation] 癌免疫療法と腫瘍をとりまく免疫微小環境2022

    • Author(s)
      廣橋 良彦
    • Organizer
      第26回日本がん免疫学会
    • Data Source
      KAKENHI-PROJECT-20H03460
  • [Presentation] 免疫応答をコントロールするがんの多様性2021

    • Author(s)
      廣橋 良彦
    • Organizer
      第25回日本がん免疫学会総会
    • Data Source
      KAKENHI-PROJECT-20H03460
  • [Presentation] 腫瘍浸潤リンパ球の機能とその認識する抗原2021

    • Author(s)
      廣橋 良彦
    • Organizer
      和歌山悪性腫瘍研究会
    • Data Source
      KAKENHI-PROJECT-20H03460
  • [Presentation] 乳癌転移巣を伴うリンパ節内のT-cellの分化・成熟について2021

    • Author(s)
      島 宏彰、九冨五郎、佐藤公則、和田朝香、里見蕗乃、廣橋良彦、鳥越俊彦、竹政伊知朗
    • Organizer
      第29回日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08962
  • [Presentation] 乳癌原発巣と転移リンパ節間のリンパ球の分化程度の違い2021

    • Author(s)
      島 宏彰、九冨五郎、空閑陽子、和田朝香、里見蕗乃、廣橋良彦、鳥越俊彦、竹政伊知朗
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08962
  • [Presentation] 乳癌転移巣を伴うリンパ節内のT-cellの分化・成熟について2021

    • Author(s)
      島 宏彰、九冨五郎、佐藤公則、和田朝香、里見蕗乃、廣橋良彦、鳥越俊彦、竹政伊知朗
    • Organizer
      第29回日本乳癌学会
    • Data Source
      KAKENHI-PROJECT-20K08962
  • [Presentation] Proteogenomic approach for natural HLA class I ligand peptides of cancer cells.2019

    • Author(s)
      Torigoe T, Kanaseki T, Hirohashi Y, Tsukahara T, Nakatsugawa M, Kubo T, Shinkawa T.
    • Organizer
      EMBL Conference: Cancer Genomics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Immunopathological properties of fibroblastic niche for cancer stem cells.2019

    • Author(s)
      Torigoe T, Hirohashi Y
    • Organizer
      SITC 34th Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Analysis of the molecular mechanism for cancer cell hormesis.2019

    • Author(s)
      Torigoe T, Hirohashi Y
    • Organizer
      9th International Congress on Stress Responses in Biology and Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] 組織レベルにおけるがん免疫応答解析2018

    • Author(s)
      廣橋 良彦
    • Organizer
      第59回日本組織細胞化学会総会・学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Immunoreaction to cancer stem cells2017

    • Author(s)
      廣橋良彦
    • Organizer
      第63回日本病理学会秋期特別総会
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] がん幹細胞に注目したがん免疫療法2017

    • Author(s)
      廣橋良彦、塚原智英、金関貴幸、中津川宗秀、久保輝文、鳥越俊彦
    • Organizer
      第76回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] 癌精巣抗原BORISは婦人科癌幹細胞性に関与し、免疫療法のターゲットになりうる2017

    • Author(s)
      廣橋良彦、浅野拓也、鳥越俊彦
    • Organizer
      第56回日本臨床細胞学会秋期大会
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] Immunothrapeutic strategy targeting cancer-stem cells2017

    • Author(s)
      Yoshihiko Hirohashi
    • Organizer
      The 36th Sapporo International Cancer Symposium
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Phosphorylation of HSF1 at Ser326 residue is associated with the maintenance of gynecologic cancer stem cells.2017

    • Author(s)
      Toshihiko Torigoe, Yoshihiko Hirohashi, Kazuyo Yasuda, Aiko Murai, Tsuyoshi Saito, Noriyuki Sato
    • Organizer
      The Eighth International Congress on Stress Proteins in Biology and Medicine
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] Molecular Mechanism of Cancer Cell Hormesis2017

    • Author(s)
      鳥越俊彦、廣橋良彦
    • Organizer
      2017年度生命科学系学会合同年次大会
    • Data Source
      KAKENHI-PROJECT-17H01540
  • [Presentation] 癌精巣抗原BORISの肺癌幹細胞様細胞における発現とBORIS抗原を標的とした免疫療法の検討2016

    • Author(s)
      堀部 亮多、廣橋 良彦
    • Organizer
      第20回日本がん免疫学会総会
    • Place of Presentation
      大阪国際交流センター(大阪市)
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] がん精巣抗原は、がん幹細胞標的免疫療法の有力な候補になる2016

    • Author(s)
      廣橋 良彦
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター(仙台市)
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] がん幹細胞標的免疫療法の開発2016

    • Author(s)
      廣橋 良彦
    • Organizer
      第14回日本臨床腫瘍学会学術集会
    • Place of Presentation
      神戸国際展示場・神戸国際会議場(神戸市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] 免疫療法でがんは治せるのか?  ~次世代のがん免疫療法~2015

    • Author(s)
      廣橋良彦
    • Organizer
      日本耳鼻咽喉科学会第98回和歌山地方部会総会
    • Place of Presentation
      和歌山県民文化会館(和歌山市)
    • Year and Date
      2015-07-05
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] がん幹細胞を標的とした免疫療法2015

    • Author(s)
      廣橋良彦
    • Organizer
      第5回北海道探索病理学研究シンポジウム
    • Place of Presentation
      ニューオータニイン札幌(札幌市)
    • Year and Date
      2015-10-24
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] Establishment of cancer stem cell-targeting immunotherapy2015

    • Author(s)
      廣橋良彦
    • Organizer
      第13回日本臨床腫瘍学会学術集会
    • Place of Presentation
      ロイトン札幌(札幌市)
    • Year and Date
      2015-07-16
    • Invited
    • Data Source
      KAKENHI-PROJECT-15H04722
  • [Presentation] SVN-2Bペプチドがんワクチン療法:第Ⅰ相臨床試験”SUCCESS"から得た最新の知見2014

    • Author(s)
      島 宏彰、水口 徹、里見 蕗乃、九冨 五郎、信岡 隆幸、木村 康利、古畑 智久、亀嶋 秀和、高橋あかり、塚原 智英、金関 貴幸、廣橋 良彦、鶴間 哲弘、岩山 祐司、田村 保明、鳥越 俊彦、佐藤 昇志、平田 公一
    • Organizer
      第18回日本がん免疫学会総会
    • Place of Presentation
      ひめぎんホール(松山市)
    • Year and Date
      2014-07-31
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Presentation] The latest finding from SUCCESS : A phase I study of SVN-2B vaccination for metastatic gastrointestinal cancer patients2014

    • Author(s)
      島 宏彰、水口 徹、里見 蕗乃、九冨 五郎、信岡 隆幸、木村 康利、古畑 智久、廣橋 良彦、鳥越 俊彦、佐藤 昇志、平田 公一
    • Organizer
      第73回日本癌学会学術総会
    • Place of Presentation
      パシフィコ横浜(横浜市)
    • Year and Date
      2014-09-26
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Presentation] A novel cancer-initiating cell marker, OR7C1 can be a target of immunotherapy2013

    • Author(s)
      Yoshihiko Hirohashi, Toshihiko Torigoe, Rena Morita, Satoshi Nishizawa, Satoko Inoda, Akari Takahashi and Noriyuki Sato
    • Organizer
      第72回日本がん学会総会
    • Place of Presentation
      横浜市
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] 新規HSP40ファミリーDNAJB8はがん幹細胞の維持に関わり、免疫療法の標的となりうる2013

    • Author(s)
      廣橋良彦、鳥越俊彦、西澤 哲、原 勲、佐藤昇志
    • Organizer
      日本ハイパーサーミア学会第30回大会
    • Place of Presentation
      横浜市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] 腎臓癌の幹細胞と治療戦略2013

    • Author(s)
      廣橋良彦
    • Organizer
      第6回 Tokyo Metropolitan Kidney Cancer Meeting
    • Place of Presentation
      東京
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] がん幹細胞におけるストレス応答遺伝子の活性化とその意義2013

    • Author(s)
      廣橋良彦
    • Organizer
      第102回日本病理学会総会
    • Place of Presentation
      札幌市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] がん幹細胞を標的とする免疫療法の基礎的検討2013

    • Author(s)
      廣橋良彦、鳥越俊彦、守田玲菜、西澤 哲、井野田智子、髙橋あかり、佐藤昇志
    • Organizer
      第17回日本がん免疫学会総会
    • Place of Presentation
      宇部市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] 熱ショックによりがん抗原特異的細胞傷害活性T細胞機能が亢進する2013

    • Author(s)
      廣橋良彦、鳥越俊彦、髙橋あかり、佐藤昇志
    • Organizer
      第29回日本ストレス学会総会
    • Place of Presentation
      徳島市
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] がん幹細胞標的ペプチドワクチン2012

    • Author(s)
      廣橋良彦
    • Organizer
      第10回日本臨床腫瘍学会学術総会
    • Place of Presentation
      大阪
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Presentation] Cancer Immunotherapy targeting to cancer stem cell/cancer initiating cell2012

    • Author(s)
      廣橋良彦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌市
    • Data Source
      KAKENHI-PROJECT-24659592
  • [Presentation] Stress Response Genes Expressed in Cancer Stem Cells-potent molecular targets for cancer therapy-2011

    • Author(s)
      Toshihiko Torigoe, Hirohashi Yoshihiko, Yasuaki Tamura, Noriyuki Sato
    • Organizer
      The 5^<th> International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Quebec City, Canada.
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] がん幹細胞の免疫病理学的特性の解析:がん幹細胞標的治療へ向けて2011

    • Author(s)
      鳥越俊彦、廣橋良彦、佐藤昇志
    • Organizer
      バイオセラピィ学会シンポジウム
    • Place of Presentation
      和歌山
    • Year and Date
      2011-12-01
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] がん幹細胞の免疫学的特性とワクチン開発2011

    • Author(s)
      鳥越俊彦、廣橋良彦、田村保明、佐藤昇志
    • Organizer
      がん免疫学会シンポジウム
    • Place of Presentation
      大阪
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] 次世代がんワクチン:がん幹細胞標的ペプチドワクチンの実用化研究2011

    • Author(s)
      鳥越俊彦、廣橋良彦、守田玲菜、田村保明、平田公一、佐藤昇志
    • Organizer
      日本癌治療学会シンポジウム
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] Stress Response Genes Expressed in Cancer Stem Cells-potent molecular targets for cancer therapy2011

    • Author(s)
      Toshihiko Torigoe, Hirohashi Yoshihiko, Yasuaki Tamura, Noriyuki Sato
    • Organizer
      The 5^<th> International Congress on Stress Responses in Biology and Medicine
    • Place of Presentation
      Quebec City, Canada
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] がん幹細胞の免疫学的特性とワクチン開発2011

    • Author(s)
      鳥越俊彦、廣橋良彦、佐藤昇志
    • Organizer
      第13回癌治療増感研究シンポジウム
    • Place of Presentation
      奈良
    • Year and Date
      2011-02-11
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] がん幹細胞を標的とする免疫療法2011

    • Author(s)
      廣橋良彦、佐藤昇志, 他
    • Organizer
      第70回日本癌学会学術総会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] がん幹細胞を標的とする免疫療法2011

    • Author(s)
      廣橋良彦、鳥越俊彦、井野田智子、守田玲菜、高橋あかり、中津川宗秀、道振義貴、佐藤昇志
    • Organizer
      第70回日本癌学会学術総会、シンポジウム
    • Place of Presentation
      名古屋
    • Year and Date
      2011-10-03
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] Immune responses against cancer stem cells2010

    • Author(s)
      Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Sato
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] Immune responses against cancer stem cells2010

    • Author(s)
      Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Sato
    • Organizer
      第69回日本癌学会学術総会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-22
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] Cancer initiating cellを標的とした免疫療法の基礎的研究2010

    • Author(s)
      鳥越俊彦、廣橋良彦、佐藤昇志
    • Organizer
      日本がん免疫学会、シンポジウム
    • Place of Presentation
      熊本
    • Year and Date
      2010-07-22
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] A novel DNAJ family protein is a cancer initiating cell antigen.-A potent molecular target for cancer immunotherapy-2010

    • Author(s)
      Toshihiko Torigoe, Yoshihiko Hirohashi, Satoshi Nishizawa, Akari Takahashi, Hiroko Asanuma, Munehide Nakatsugawa, Kenjiro Kamiguchi, Alisa A. Sokolovskaya, Noriyuki Sato.
    • Organizer
      The 8^<th> International Workshop on the Molecular Biology of Stress Responses
    • Place of Presentation
      Seorak Mt., Korea
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] A novel DNAJ family protein is a cancer initiating cell antigen.-A potent molecular target for cancer immunotherapy2010

    • Author(s)
      Toshihiko Torigoe, Yoshihiko Hirohashi, Satoshi Nishizawa, Akari Takahashi, Hiroko Asanuma, Munehide Nakatsugawa, Kenjiro Kamiguchi, Alisa A. Sokolovskaya, Noriyuki Sato
    • Organizer
      The 8th International Workshop on the Molecular Biology of Stress Responses
    • Place of Presentation
      Seorak Mt., Korea
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] ヒト癌幹細胞に対する免疫応答2009

    • Author(s)
      廣橋良彦、鳥越俊彦、佐藤昇志
    • Organizer
      免疫アジュバント研究会
    • Place of Presentation
      洞爺
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] Identification of cancer stem cell antigens revealed unique characteristics of triple negative breast cancer2009

    • Author(s)
      Torigoe, T., Hirohashi, Y., Takahashi, A., Asanuma, H., Nakatsugawa, M., Inoda, S., Sato, N.
    • Organizer
      14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine
    • Place of Presentation
      Loutraki, Greece
    • Data Source
      KAKENHI-PROJECT-21590401
  • [Presentation] Identification of cancer stem cell antigens revealed unique characteristics of triple negative breast cancer2009

    • Author(s)
      Torigoe, T., Hirohashi, Y., Takahashi, A., Asanuma, H., Nakatsugawa, M., Inoda, S., Sato, N.
    • Organizer
      14th World Congress on Advances in Oncology and 12th International Symposium on Molecular Medicine
    • Place of Presentation
      Loutraki, Greece
    • Data Source
      KAKENHI-PROJECT-21249025
  • [Presentation] ヒトがん幹細胞免疫制御の分子病理学的基盤

    • Author(s)
      廣橋良彦
    • Organizer
      第60回日本病理学会秋季特別総会
    • Place of Presentation
      国立劇場おきなわ(沖縄県・浦添市)
    • Year and Date
      2014-11-19 – 2014-11-20
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] がん幹細胞標的ペプチドワクチン

    • Author(s)
      廣橋良彦
    • Organizer
      第10回日本臨床腫瘍学会学術総会
    • Place of Presentation
      大阪
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] Cancer Immunotherapy targeting to cancer stem cell/cancer initiating cell

    • Author(s)
      廣橋良彦
    • Organizer
      第71回日本癌学会学術総会
    • Place of Presentation
      札幌
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • [Presentation] 6.Cytotoxic T lymphocytes play a key role in immunological responses to human cancer stem-like cells

    • Author(s)
      廣橋良彦
    • Organizer
      第33回 札幌がんセミナー国際シンポジウム
    • Place of Presentation
      ロイトン札幌(北海道・札幌市)
    • Year and Date
      2014-06-28 – 2014-06-29
    • Invited
    • Data Source
      KAKENHI-PROJECT-24590449
  • 1.  TORIGOE Toshihiko (20301400)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 84 results
  • 2.  KUTOMI Goro (10404625)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 3.  竹政 伊知朗 (50379252)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 3 results
  • 4.  SATO Noriyuki (50158937)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 40 results
  • 5.  TAMURA Yasuaki (80322329)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 29 results
  • 6.  島 宏彰 (00404616)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 7.  和田 朝香 (10830151)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 8.  ICHIMIYA Shingo (30305221)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 9.  KIKUCHI Tomoki (50404588)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  HIRATA Koichi (50136959)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 11.  MIZUGUCHI Toru (30347174)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 12.  KIMURA Yasutoshi (80311893)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 13.  OGAWA Tadashi (70516658)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  KOUNO Tsuyoshi (50516664)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  Kitamura Hiroshi (00404674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 16.  Murata Masaki (10404592)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  舛森 直哉 (20295356)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  前田 俊浩 (40438015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  橋本 真一 (00313099)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 20.  塚原 智英 (20404634)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 12 results
  • 21.  金関 貴幸 (50531266)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 9 results
  • 22.  久保 輝文 (90580019)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 23.  中津川 宗秀 (70448596)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 24.  里見 蕗乃 (90563487)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 25.  高澤 啓 (00593021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  奥谷 浩一 (70457703)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  秋月 恵美 (20404626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  佐藤 雄 (50583556)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  石井 雅之 (50643201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  浜部 敦史 (60621034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  沖田 憲司 (70517911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  福谷 洋介 (50747136)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 35.  上野 秀樹 (90597535)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 36.  梶原 由規 (20753023)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 37.  望月 早月 (80365428)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 38.  岡本 耕一 (20783517)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 39.  田中 利明 (40263446)
    # of Collaborated Projects: 1 results
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  • 40.  宮崎 晃亘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 41.  宮本 昇
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 42.  江森 誠人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 43.  松島 綱治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 44.  斉藤 豪
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 45.  小海 康夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 46.  原 勲
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 47.  染谷 正則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 48.  後町 俊夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 49.  VITALY Kochin
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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